keyword
MENU ▼
Read by QxMD icon Read
search

Digital Pathology

keyword
https://www.readbyqxmd.com/read/29684514/an-analysis-of-radiation-effects-in-digital-subtraction-angiography-of-intracranial-artery-stenosis
#1
Chaoqun Guo, Xiaolei Shi, Xianhui Ding, Zhiming Zhou
BACKGROUND: Intracranial artery stenosis (IAS) is the most common cause for acute cerebral accidents. Digital subtraction angiography (DSA) is the gold standard to detect IAS, and usually brings excess radiation exposure to examinees and examiners. The artery pathology might influence the interventional procedure, causing a prolonged radiation effects. However, no studies are available on the association between IAS pathology and operational parameters. METHODS: A retrospective analysis was conducted on 93 patients with first-ever stroke/transient ischemic attack (TIA), who received DSA examination within 3 months from onset in this single center...
April 20, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29684099/comparative-analysis-of-tissue-reconstruction-algorithms-for-3d-histology
#2
Kimmo Kartasalo, Leena Latonen, Jorma Vihinen, Tapio Visakorpi, Matti Nykter, Pekka Ruusuvuori
Motivation: Digital pathology enables new approaches that expand beyond storage, visualization or analysis of histological samples in digital format. One novel opportunity is 3D histology, where a three-dimensional reconstruction of the sample is formed computationally based on serial tissue sections. This allows examining tissue architecture in 3D, for example, for diagnostic purposes. Importantly, 3D histology enables joint mapping of cellular morphology with spatially resolved omics data in the true 3D context of the tissue at microscopic resolution...
April 19, 2018: Bioinformatics
https://www.readbyqxmd.com/read/29682069/ruptured-distal-anterior-choroidal-artery-aneurysm-presenting-as-isolated-intraventricular-hemorrhage-case-report-and-comprehensive-review-of-the-literature
#3
Chi Hau Tan, Leon T Lai, Ronil V Chandra
Distal anterior choroidal artery (AChA) aneurysms are infrequent. We discuss the case of a 59-year-old patient who presented with an isolated intraventricular hemorrhage (IVH) secondary to a ruptured distal AChA aneurysm. Initial noninvasive cerebral computed tomography angiography revealed no evidence of an underlying vascular pathology. The patient underwent further digital subtraction cerebral angiography, which revealed an aneurysm arising from the distal AChA segment. The aneurysm was successfully treated with surgical clip ligation...
April 2018: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29675359/three-dimensional-speckle-tracking-echocardiography-detects-different-patterns-of-right-atrial-dysfunction-in-selected-disorders-a-short-summary-from-the-magyar-path-study
#4
Attila Nemes, Péter Domsik, Anita Kalapos, Árpád Kormányos, Nóra Ambrus, Tamás Forster
The right atrium (RA) is the most under-evaluated heart chamber in the clinical practice. Three-dimensional (3D) speckle-tracking echocardiography (STE) merges the benefits of 3D echocardiography and STE: volumetric and strain assessment of the RA can be performed at the same time from the same digitally acquired 3D echocardiographic dataset with a special equipment using a virtual 3D model of the RA. A diagnostic focused study is under way at the Second Department of Medicine and Cardiology Center, University of Szeged, Hungary to assess 3D-STE-derived RA variables in different patient populations, which serves as a substudy of Motion Analysis of the heart and Great vessels bY three-dimensionAl speckle-tRacking echocardiography in Pathological cases (MAGYAR-Path) Study...
March 2018: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/29673113/evaluation-of-photoshop-based-image-analysis-in-cytologic-diagnosis-of-pleural-fluid-in-comparison-with-conventional-modalities
#5
Amir Hossein Jafarian, Aida Tasbandi, Nema Mohamadian Roshan
BACKGROUND: The aim of this study is to investigate and compare the results of digital image analysis in pleural effusion cytology samples with conventional modalities. MATERIALS AND METHODS: In this cross-sectional study, 53 pleural fluid cytology smears from Qaem hospital pathology department, located in Mashhad, Iran were investigated. Prior to digital analysis, all specimens were evaluated by two pathologists and categorized into three groups as: benign, suspicious, and malignant...
April 19, 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29672311/inverse-association-of-prostatic-chronic-inflammation-among-prostate-cancer-tumor-grade-groups-retrospective-study-of-738-consecutive-cases-elected-to-a-first-random-biopsy-set
#6
Antonio Benito Porcaro, Alessandro Tafuri, Giovanni Novella, Marco Sebben, Arianna Mariotto, Davide Inverardi, Paolo Corsi, Tania Processali, Marco Pirozzi, Nelia Amigoni, Riccardo Rizzetto, Matteo Brunelli, Matteo Balzarro, Salvatore Siracusano, Walter Artibani
OBJECTIVES: The study aimed to evaluate associations of prostatic chronic inflammation (PCI) with prostate cancer (PCA) grade groups by the International Society of Urological Pathology (ISUP). METHODS: The study evaluated retrospectively 738 cases. The patient population was sampled into 3 groups collecting cases without and with PCA including subjects with lSUP grade group 1 and grade groups 2-5. RESULTS: PCI was assessed in 185 patients (25...
April 19, 2018: Urologia Internationalis
https://www.readbyqxmd.com/read/29670857/radiomics-evaluation-of-histological-heterogeneity-using-multiscale-textures-derived-from-3d-wavelet-transformation-of-multispectral-images
#7
Ahmad Chaddad, Paul Daniel, Tamim Niazi
Purpose: Colorectal cancer (CRC) is markedly heterogeneous and develops progressively toward malignancy through several stages which include stroma (ST), benign hyperplasia (BH), intraepithelial neoplasia (IN) or precursor cancerous lesion, and carcinoma (CA). Identification of the malignancy stage of CRC pathology tissues (PT) allows the most appropriate therapeutic intervention. Methods: This study investigates multiscale texture features extracted from CRC pathology sections using 3D wavelet transform (3D-WT) filter...
2018: Frontiers in Oncology
https://www.readbyqxmd.com/read/29669609/neuropsychological-test-performance-in-parkinsonism-without-dopaminergic-deficiency-on-123i-fp-cit-spect-imaging
#8
Kathryn A Wyman-Chick, Phillip K Martin, Michal Minár, Manuel Menéndez-González, Lauren O Erickson, Tania Álvarez-Avellón, Ryan W Schroeder
OBJECTIVES: To examine neuropsychological test performance among individuals clinically diagnosed with Parkinson's disease (PD) without evidence of dopaminergic deficiency on [123]I-CIT single photon emission computed tomography imaging. METHODS: Data were obtained from the Parkinson's Progression Marker Initiative. The sample included 59 participants with scans without evidence of dopaminergic deficiency (SWEDD), 412 with PD, and 114 healthy controls (HC). Tests included Judgment of Line Orientation, Letter-Number Sequencing, Symbol Digit Modalities, Hopkins Verbal Learning Test-Revised, and Letter and Category Fluency...
April 19, 2018: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/29667148/sublingual-nodules-diagnostic-markers-of-metastatic-breast-cancer
#9
Xue Yang, Cui-Hong Zhu, Rui Cao, Jian Hao, Xiong-Zhi Wu
OBJECTIVE: To evaluate the diagnostic significance of sublingual nodules for metastasis of patients with breast cancer and further to explore the mechanisms of sublingual nodules. METHODS: The image data of 117 in-patients with breast cancer in stage I-IV in Tianjin Medical University Cancer Institute and Hospital from December 2009 to September 2011 were assessed retrospectively. All photos of patients' tongue were recorded by the digital camera of uniform type within 1 month after serological examination and regular re-examined by computed tomography (CT), magnetic resonance imaging and positron emission tomography CT...
April 17, 2018: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29666814/digital-chest-tomosynthesis-the-2017-updated-review-of-an-emerging-application
#10
REVIEW
Arianna Ferrari, Luca Bertolaccini, Piergiorgio Solli, Paola Oriana Di Salvia, David Scaradozzi
Lung cancer is the leading cause of cancer death and second most common cancer among both men and women, but most of them are detected when patients become symptomatic and in late-stage. Chest radiography (CR) is a basic technique for the investigation of lung cancer and has the benefit of convenience and low radiation dose, but detection of malignancy is often difficult. The introduction of computed tomography (CT) for screening has increased the proportion of lung cancer detected but with higher exposure dose and higher costs...
March 2018: Annals of Translational Medicine
https://www.readbyqxmd.com/read/29665178/digital-cytology-a-short-review-of-technical-and-methodological-approaches-and-applications
#11
REVIEW
Arrigo Capitanio, Roberto E Dina, Darren Treanor
By the last decade of the 20th Century digital imaging rapidly replaced film-based imaging in many medical fields. Radiology is certainly the most significant example of this technological change, but also in microscopy at the beginning of the current century it became difficult to find a conventional film camera in a Department of Pathology. Thanks to the constant increase of the power and speed of microcomputers, the year-by-year reduction in costs and their ease of use, digital cameras took their place on the head of the microscope replacing the conventional film camera...
April 17, 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29663843/persistent-hematospermia-seminal-vesicle-bleed
#12
Yih Chyn Phan, Wasim Mahmalji
A 65-year-old gentleman, with no past medical problems and not on any anticoagulation was seen in the urology clinic with persistent hematospermia for the last few years. A thorough history and examination including a digital examination of the prostate was unremarkable. Bleeding from his female partner was also ruled out. Investigations such as prostate specific antigen (PSA) blood test, urine culture, semen culture, and flexible cystoscopy were performed, and these investigations were also within normal limits...
April 17, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29660164/high-grade-panin-presenting-with-localized-stricture-of-the-main-pancreatic-duct-a-clinicopathological-and-molecular-study-of-10-cases-suggests-a-clue-for-the-early-detection-of-pancreatic-cancer
#13
Masataka Yokode, Masayuki Akita, Kohei Fujikura, Mi-Ju Kim, Yukiko Morinaga, Seiichi Yoshikawa, Takuro Terada, Hiroshi Matsukiyo, Takuma Tajiri, Shiho Abe-Suzuki, Tomoo Itoh, Seung-Mo Hong, Yoh Zen
AIMS: This study aimed to identify the pathological features of high-grade PanIN that presents with imaging-detectable abnormalities. METHODS AND RESULTS: Ten cases of isolated, main-duct, high-grade PanIN as the primary clinical presentation were identified. All patients presented with stenosis of the main pancreatic duct, with 2 being associated with extensive upstream duct dilatation (>5 mm in diameter). Pancreatic juice cytology suggested adenocarcinoma in all 7 cases examined...
April 16, 2018: Histopathology
https://www.readbyqxmd.com/read/29658053/flow-and-air-conditioning-simulations-of-computer-turbinectomized-nose-models
#14
J Pérez-Mota, F Solorio-Ordaz, J Cervantes-de Gortari
Air conditioning for the human respiratory system is the most important function of the nose. When obstruction occurs in the nasal airway, turbinectomy is used to correct such pathology. However, mucosal atrophy may occur sometime after this surgery when it is overdone. There is not enough information about long-term recovery of nasal air conditioning performance after partial or total surgery. The purpose of this research was to assess if, based on the flow and temperature/humidity characteristics of the air intake to the choana, partial resection of turbinates is better than total resection...
April 16, 2018: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29652651/prediction-of-organ-involvement-in-systemic-sclerosis-by-serum-biomarkers-and-peripheral-endothelial-function
#15
Shin-Ya Kawashiri, Ayako Nishino, Takashi Igawa, Ayuko Takatani, Toshimasa Shimizu, Masataka Umeda, Shoichi Fukui, Akitomo Okada, Takahisa Suzuki, Tomohiro Koga, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Munetoshi Nakashima, Akinari Mizokami, Naoki Matsuoka, Kiyoshi Migita, Fumihide Ogawa, Satoshi Ikeda, Koji Maemura, Hideki Nakamura, Tomoki Origuchi, Takahiro Maeda, Atsushi Kawakami
OBJECTIVES: To identify prognostic factors among serum biomarkers and endothelial vasodilator function findings in patients with systemic sclerosis (SSc). METHODS: This is a clinical observational study. We assessed 60 consecutive SSc patients (44 limited cutaneous-type, 16 diffuse cutaneous-type). Circulating growth differentiation factor-15 (GDF-15), placenta growth factor (PlGF), endostatin, vascular endothelial growth factor (VEGF), and pentraxin 3 (PTX3) were measured by ELISA...
April 12, 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29651638/improvement-in-diagnostic-performance-of-breast-cancer-comparison-between-conventional-digital-mammography-alone-and-conventional-mammography-plus-digital-breast-tomosynthesis
#16
Ryoko Ohashi, Michinobu Nagao, Izumi Nakamura, Takahiro Okamoto, Shuji Sakai
BACKGROUND: The aim of this study was to determine if the diagnostic performance of breast lesion examinations could be improved using both digital breast tomosynthesis (DBT) and conventional digital mammography (CDM). METHODS: Our institutional review board approved the protocol, and patients were provided the opportunity to opt out of the study. A total of 628 patients aged 22-91 years with abnormal screening results or clinical symptoms were consecutively enrolled between June 2015 and March 2016...
April 12, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/29650781/anatomic-and-angiographic-analyses-of-ophthalmic-artery-collaterals-in-moyamoya-disease
#17
T Robert, G Cicciò, P Sylvestre, A Chiappini, A G Weil, S Smajda, C Chaalala, R Blanc, M Reinert, M Piotin, M W Bojanowski
BACKGROUND AND PURPOSE: Moyamoya disease is a progressive neurovascular pathology defined by steno-occlusive disease of the distal internal carotid artery and associated with the development of compensatory vascular collaterals. The etiology and exact anatomy of vascular collaterals have not been extensively studied. The aim of this study was to describe the anatomy of collaterals developed between the ophthalmic artery and the anterior cerebral artery in a Moyamoya population. MATERIALS AND METHODS: All patients treated for Moyamoya disease from 2004 to 2016 in 4 neurosurgical centers with available cerebral digital subtraction angiography were included...
April 12, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29630047/simple-and-rapid-method-to-obtain-high-quality-tumor-dna-from-clinical-pathological-specimens-using-touch-imprint-cytology
#18
Kenji Amemiya, Yosuke Hirotsu, Toshio Oyama, Masao Omata
It is critical to determine the mutational status in cancer before administration and treatment of specific molecular targeted drugs for cancer patients. In the clinical setting, formalin-fixed paraffin-embedded (FFPE) tissues are widely used for genetic testing. However, FFPE DNA is generally damaged and fragmented during the fixation process with formalin. Therefore, FFPE DNA is sometimes not adequate for genetic testing because of low quality and quantity of DNA. Here we present a method of touch imprint cytology (TIC) to obtain genomic DNA from cancer cells, which can be observed under a microscope...
March 21, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29630046/multimodal-hierarchical-imaging-of-serial-sections-for-finding-specific-cellular-targets-within-large-volumes
#19
Irene U Wacker, Lisa Veith, Waldemar Spomer, Andreas Hofmann, Marlene Thaler, Stefan Hillmer, Ulrich Gengenbach, Rasmus R Schröder
Targeting specific cells at ultrastructural resolution within a mixed cell population or a tissue can be achieved by hierarchical imaging using a combination of light and electron microscopy. Samples embedded in resin are sectioned into arrays consisting of ribbons of hundreds of ultrathin sections and deposited on pieces of silicon wafer or conductively coated coverslips. Arrays are imaged at low resolution using a digital consumer like smartphone camera or light microscope (LM) for a rapid large area overview, or a wide field fluorescence microscope (fluorescence light microscopy (FLM)) after labeling with fluorophores...
March 20, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29628427/external-apical-root-resorption-diagnosis-by-using-fii-human-dentine-fraction-and-salivary-igg
#20
Tânia Maris Pedrini Soares Da-Costa, Mirian Marubayashi Hidalgo, Alberto Consolaro, Carlos Eduardo de Oliveira Lima, Evelise Ono Tanaka, Eiko Nakagawa Itano
BACKGROUND: External apical root resorption as a consequence of orthodontic treatment is an inflammatory pathological process that results in permanent loss of tooth structure from the root apex. OBJECTIVES: This study aimed to investigate the diagnostic potential of human dentine fractions and salivary IgG in external apical root resorption. PATIENTS AND METHODS: Saliva samples were collected from 10 patients before (T0) and after 3 (T3), 6 (T6) and 12 (T12) months of orthodontic treatment...
April 5, 2018: International Orthodontics
keyword
keyword
43377
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"