keyword
https://read.qxmd.com/read/38496349/cauda-equina-conus-medullaris-and-syndromes-mimicking-sciatic-pain-wfns-spine-committee-recommendations
#1
REVIEW
Sandeep Vaishya, Mirza Pojskic, Manbachan Singh Bedi, Joachim Oertel, Christoph Sippl, Scott Robertson, Corinna Zygourakis
INTRODUCTION: Cauda equina syndrome (CES), conus medullaris syndrome (CMS), and sciatica-like syndromes or "sciatica mimics" (SM) may present as diagnostic and/or therapeutic dilemmas for the practicing spine surgeon. There is considerable controversy regarding the appropriate definition and diagnosis of these entities, as well as indications for and timing of surgery. Our goal is to formulate the most current, evidence-based recommendations for the definition, diagnosis, and management of CES, CMS, and SM syndromes...
April 2024: World neurosurgery: X
https://read.qxmd.com/read/38291726/giant-myxopapillary-ependymoma-with-multi-site-neural-axis-metastases-a-rare-case-with-suboptimal-outcome
#2
JOURNAL ARTICLE
Arturs Balodis, Viktorija Ņeverčika, Marija Zavertjajeva, Raimonds Mikijanskis, Marika Kalniņa, Austra Breikša-Vaivode, Inese Briede
BACKGROUND Myxopapillary ependymoma is a rare type of slow-growing tumor that mainly occurs in the spinal cord, particularly in the region of the conus medullaris and the cauda equina. It originates from the ependymal glial cells found in the filum terminale. CASE REPORT We present a clinical case of a 44-year-old male patient who presented with symptoms of non-specific pain in the lower back persisting for the past 2 years. He did not report any specific neurological deficits or radicular symptoms. Unenhanced MRI of the lumbar spine showed a giant intradural, extramedullary, heterogenous, expansive tumor at the level L1-S4 with erosion of the sacral bone and invasion of presacral tissue...
January 31, 2024: American Journal of Case Reports
https://read.qxmd.com/read/38276067/recurrent-acute-disseminated-encephalomyelitis-presenting-as-conus-medullaris-syndrome-a-case-report
#3
Dae-Wook Lee, Seok Kang, Nackhwan Kim
Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating disorder that typically follows an infection or recent vaccination. Symptoms such as encephalopathy and focal neurological deficits appear weeks after the initial illness, leading to swift and progressive neurological decline. While ADEM in the brain has been well documented, reports of ADEM, specifically in the spinal cord, are relatively limited. A 58-year-old male presented with rapidly progressive bilateral lower extremity tingling, numbness, and mild gait disturbance approximately two days prior to visiting the emergency room...
January 22, 2024: Medicina
https://read.qxmd.com/read/37987342/high-riding-conus-medullaris-syndrome-a-case-report-and-literature-review-its-comparison-with-cauda-equina-syndrome
#4
REVIEW
Ya-Lin Huang, Shin-Tsu Chang
INTRODUCTION: Conus medullaris syndrome (CMS) is a distinctive spinal cord injury (SCI), which presents with varying degrees of upper motor neuron signs (UMNS) and lower motor neuron signs (LMNS). Herein, we present a case with a burst fracture injury at the proximal Conus Medullaris (CM). CASE PRESENTATION: A 48-year-old Taiwanese male presenting with lower back pain and paraparesis was having difficulty standing independently after a traumatic fall. An Imaging survey showed an incomplete D burst fracture of the T12 vertebra...
October 27, 2023: Tomography: a Journal for Imaging Research
https://read.qxmd.com/read/37976712/recurrent-intramedullary-endometriosis-of-the-conus-medullaris-a-case-report-of-diagnostic-pitfalls-and-a-review-of-literature
#5
Deshan Gomez, Gayanga Kottegoda, Thanuka Gunawardana, Pathmanesan Pirakash, Deepal Attanayake
INTRODUCTION: Endometriosis is a common gynaecologcial disorder and is characterized by the presence and implantation of endometrial epithelium and glandular stroma in an extrauterine location Intraspinal endometriosis can involve the intramedullary, subarachnoid, intradural-extramedullary, and extradural compartments, including the vertebral bodies. Symptoms due to intraspinal endometriosis will vary depending on the location and degree of compression of neural structures and will fluctuate with the menstrual cycle...
December 2023: International Journal of Surgery Case Reports
https://read.qxmd.com/read/37941626/resection-of-a-lumbar-intradural-tumor
#6
Joseph Yunga Tigre, Andrew J Kloehn, Ava Scemama, James Boddu, Meredith C Costello, Allan D Levi, S Shelby Burks
BACKGROUND: Myxopapillary ependymomas and schwannomas represent the most common tumors of the conus medullaris and cauda equina. Here, we present the surgical resection of a 64-year-old male with a lumbar intradural tumor. CASE DESCRIPTION: A 64-year-old male presented with several months of the lower extremity weakness, pain, and bowel/bladder dysfunction. Magnetic resonance imaging demonstrated a large L3-5 intradural lesion, and surgical resection using intraoperative neuromonitoring with somatosensory evoked potentials (SSEPs), motor evoked potentials (MEPs), free-running electromygraphy (EMGs), and direct sphincter monitoring was recommended...
2023: Surgical Neurology International
https://read.qxmd.com/read/37899261/neurological-analysis-based-on-the-terminal-end-of-the-spinal-cord-and-the-narrowest-level-of-injured-spine-in-thoracolumbar-spinal-injuries
#7
JOURNAL ARTICLE
Yuji Hatakeyama, Michio Hongo, Tadato Kido, Masakazu Urayama, Yuji Kasukawa, Hiroshi Sasaki, Toshiaki Aizawa, Daisuke Kudo, Ryota Kimura, Yuichi Ono, Fumihito Kasama, Naohisa Miyakoshi
This study aimed to clarify neurological differences among the epiconus, conus medullaris, and cauda equina syndromes. Eighty-seven patients who underwent surgery for acute thoracolumbar spinal injuries were assessed. We defined the epiconus as the region from the terminal end of the spinal cord to the proximal 1.0 to 2.25 vertebral bodies, the conus medullaris as the region proximal to < 1.0 vertebral bodies, and the cauda equina as the distal part of the nerve roots originating from the spinal cord. On the basis of the distance from the terminal end of the spinal cord to the narrowest level of the spinal canal, the narrowest levels were ordered as follows: the epiconus followed by the conus medullaris and cauda equina...
October 2023: Acta Medica Okayama
https://read.qxmd.com/read/37854653/resection-of-a-large-thoracolumbar-intradural-ependymoma-a-2d-operative-video
#8
JOURNAL ARTICLE
Daniel M Aaronson, Brandon Laing, Randall Treffy, Saman Shabani
In this video, the authors present the resection of a large thoracolumbar intradural ependymoma in a 33-year-old female. The patient underwent T9-L3 laminectomies, intradural tumor resection, and posterior instrumented fixation and fusion. The surgical procedure aimed to relieve the mass effect, obtain a diagnosis, prevent further neurological decline, and achieve a potential curative resection. The pathology confirmed a myxopapillary ependymoma, a rare tumor with a preference for the conus medullaris, cauda equina, or filum terminale...
October 2023: Neurosurgical focus: Video
https://read.qxmd.com/read/37795406/stereotactic-body-radiation-therapy-to-the-spine-contouring-the-cauda-equina-instead-of-the-spinal-cord-is-more-practical-as-the-organ-at-risk
#9
JOURNAL ARTICLE
Osamu Tanaka, Takuya Taniguchi, Shuto Nakaya, Kousei Adachi, Takuji Kiryu, Chiyoko Makita, Masayuki Matsuo
BACKGROUND: Stereotactic body radiotherapy (SBRT) is recognized as a curative treatment for oligometastasis. The spinal cord becomes the cauda equina at the lumbar level, and the nerves are located dorsally. Recently, a consensus has been reached that the cauda equina should be contoured as an organ at risk (OAR). Here, we examined the separate contouring benefits for the spinal canal versus the cauda equina only as the OAR. MATERIALS AND METHODS: A medical physicist designed a simulation plan for 10 patients with isolated lumbar metastasis...
2023: Reports of Practical Oncology and Radiotherapy
https://read.qxmd.com/read/37720363/intramedullary-epidermoid-cyst-of-the-conus-medullaris-a-case-report-and-literature-review
#10
Endris Hussen, Samson Aboye, Merhawi Leake, Fadil Nuredin Abrar
BACKGROUND: Central nervous system tumors are usually located in the brain, and spinal cord tumors account for approximately 20% of central nervous system tumors. Epidermoid cysts constitute <1% of all intraspinal tumors. It consists of squamous epithelial-lined cysts containing keratin, cholesterol, and cellular granules. Epidermoid cysts can be classified as congenital, acquired, extradural, extramedullary, or intramedullary according to etiology and location. The intradural intramedullary type is uncommon...
2023: International Medical Case Reports Journal
https://read.qxmd.com/read/37640878/updates-on-intraoperative-neurophysiology-during-surgery-for-spinal-dysraphism
#11
JOURNAL ARTICLE
Claudia Pasquali, Federica Basaldella, Francesco Sala
Spinal dysraphism is a group of disorders resulting from an embryologic failure of spinal cord development which can lead to a radicular-medullary mechanical stretch that generates vascular compromise and hypoxic-ischemic damage to the nervous structures of the conus-cauda region.Thus, the clinical relevance of the different types of spinal dysraphism is related to the possible neurologic deficits resulting from spinal cord tethering. The clinical presentation is heterogenous: from asymptomatic to very compromised patients...
2023: Advances and Technical Standards in Neurosurgery
https://read.qxmd.com/read/37621120/anatomical-considerations-regarding-a-high-flow-arteriovenous-fistula-below-the-conus-medullaris-in-a-patient-with-hereditary-hemorrhagic-telangiectasia-case-report
#12
JOURNAL ARTICLE
Ángela H Schmolling, Vivek Bodani, Tanaporn Jaroenngarmsamer, Hugo Andrade-Barazarte, Ivan Radovanovic, Timo Krings
BACKGROUND AND IMPORTANCE: Cauda equina radicular arteriovenous fistulas are rare "low flow" shunting lesions characterized by direct communication between the radicular artery and vein of a cauda equina nerve root. None have been associated with hereditary hemorrhagic telangiectasia and a high-flow cauda equina radicular arteriovenous fistula has never been reported. We present a unique case of a high-flow cauda equina radicular arteriovenous fistula in a patient with hereditary hemorrhagic telangiectasia...
August 24, 2023: Interventional Neuroradiology
https://read.qxmd.com/read/37575694/pediatric-spinal-neuroschistosomiasis-in-yemen-an-overlooked-dilemma-in-an-endemic-region
#13
JOURNAL ARTICLE
Nabil Aljuma'ai, Saif A Ghabisha, Faisal Ahmed, Taha Al-Mwald, Abdullah Mayas, Bushra Almaghribi, Hamzah Esmail, Mohamed Badheeb
BACKGROUND: Neurological involvement in schistosomiasis presents a significant and serious complication. While the disease is generally considered treatable during the early stages, the rarity of this condition often leads to delays in diagnosis and treatment. This study aims to report the clinical characteristics of pediatric patients with spinal neuroschistosomiasis (NS) in an endemic area to the disease. METHODS: A retrospective cross-sectional review was conducted at Althora General Hospital in Ibb, Yemen, from January 2016 to January 2021...
July 2023: Curēus
https://read.qxmd.com/read/37410596/surgical-outcomes-and-risk-factors-for-recurrence-of-myxopapillary-ependymoma-a-single-center-experience
#14
JOURNAL ARTICLE
Mark C Dougherty, Mani Ratnesh S Sandhu, Nahom Teferi, Jennifer L Noeller, Clayton L Rosinski, Brian J Park, Arnold H Menezes, Kirill V Nourski, Patrick W Hitchon
OBJECTIVE: Myxopapillary ependymomas (MPEs) are low-grade, well-circumscribed tumors that often involve the conus medullaris, cauda equina, or filum terminale. They account for up to 5% of all tumors of the spine and 13% of spinal ependymomas, with a peak incidence between 30 and 50 years of age. Because of the rarity of MPEs, their clinical course and optimal management strategy are not well defined, and long-term outcomes remain difficult to predict. The objective of this study was to review long-term clinical outcomes of spinal MPEs and identify factors that may predict tumor resectability and recurrence...
June 30, 2023: Journal of Neurosurgery. Spine
https://read.qxmd.com/read/37260799/myxopapillary-ependymoma-a-case-report-of-rare-multicentric-subtype-and-literature-review
#15
Faisal R Almatrafi, Abdullah M Aseeri, Mohammad F Alqahtani, Liqa Al Mulla, Saeed Al-Jubran, Majed A AlOmair, Sultan Alsalmi, Rawan Al-Anazi
BACKGROUND: Myxopapillary ependymoma is a rare type of primary spinal tumor, it is distinctly a slow-growing tumor that originates in the conus medullaris, cauda equina, or film terminals and is rarely identified as a multicentric type. Myxopapillary ependymoma has a unique histological characteristic and is associated with a generally better prognosis. OBJECTIVE: We present a case of a rare multicentric myxopapillary ependymoma. CASE PRESENTATION: A 28-year-old male with 1-year history of low back pain and 3 months of radiating pain to left lower limb with perianal anesthesia...
April 2023: Medical Archives
https://read.qxmd.com/read/36698626/parp-inhibition-utilized-in-combination-therapy-with-olaparib-temozolomide-to-achieve-disease-stabilization-in-a-rare-case-of-brca1-mutant-metastatic-myxopapillary-ependymoma
#16
Preethika Mahalingam, Sam Smith, Juanita Lopez, Rajaei K Sharma, Thomas Millard, Khin Thway, Cyril Fisher, David A Reardon, Robin Jones, Andrew G Nicholson, David Cunningham, Liam Welsh, Bhupinder Sharma
Myxopapillary ependymoma (MPE) is a primary tumor of the central nervous system (CNS), characteristically an indolent malignancy involving the spinal conus medullaris, Filum terminale or cauda equina. We present a rare case of MPE, recurrent in the pelvic soft tissue with eventual pleural and intra-pulmonary metastasis. Refractory to repeated gross resection, adjuvant radiotherapy, platinum-based chemotherapy and temozolomide exploitation of mutant somatic BRCA1 status with the addition of a poly (ADP-ribose); polymerase inhibitor (PARPi) in a novel combination regimen with olaparib-temozolomide (OT) has achieved stable radiological disease after 10 cycles...
2023: Rare Tumors
https://read.qxmd.com/read/36683067/ventriculus-terminalis-cyst-in-an-infant-a-case-report
#17
JOURNAL ARTICLE
Arnold H Menezes, Yutaka Sato, Brian J Dlouhy, Karra A Jones, Steven A Moore
BACKGROUND: Filar cysts are frequently found on neonatal ultrasound and are physiologically involuting structures with natural resolution. Hence, there has been no previous histologic correlation. Ventriculus terminalis is a focal central canal dilation in the conus medullaris and usually not clinically significant. Extra-axial cyst at the conus-filum junction connected to ventriculus terminalis is extremely rare, especially when associated with tethered lipomatous filum terminale and with progressive cyst enlargement...
January 23, 2023: Journal of Medical Case Reports
https://read.qxmd.com/read/36324960/lumbar-cistern-candida-intradural-abscess-following-epidural-anesthesia
#18
Gabrielle Santangelo, Jonathan Stone, Mahlon Johnson, Kevin Walter
Background: This report describes a case of an immunocompetent patient with an intradural abscess from Candida dubliniensis . The majority of fungal spine infections, although rare in general, are due to Aspergillus or C. albicans through systemic fungemia. To date, there have only been two reports of spondylodiscitis from C. dubliniensis . Case Description: A 37-year-old immunocompetent female patient presented to the neurosurgical service for worsening headaches with nausea, vomiting, vision changes, and weight loss...
2022: Surgical Neurology International
https://read.qxmd.com/read/36321215/lower-urinary-tract-function-in-patients-with-fracture-in-thoracolumbal-junction-an-observational-study
#19
JOURNAL ARTICLE
Ana Podbregar, Gaj Vidmar, Metka Moharić
A fracture in the thoracolumbal junction may cause complete or incomplete damage to the spinal cord, conus medullaris or cauda equina and result in an isolated or mixed lesion of the upper and lower motor neurons causing leg weakness and urinary/bowel/sexual dysfunction. In this retrospective cross-sectional study, we aimed to describe electrodiagnostic and urodynamic findings after thoracolumbal fractures and determine potential discriminating factors. We identified 74 cases (mean age 42 years, range 16-79 years, 55 men) admitted to our institution between 2008 and 2018 for Th12, L1 or L2 vertebral fractures, and retrieved from their medical records available demographic, clinical, electrodiagnostic and urodynamic data...
December 1, 2022: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://read.qxmd.com/read/36188492/acute-venous-congestive-myelopathy-in-a-patient-with-neurosarcoidosis
#20
Nicola Hazel Guy
There is a range of differential diagnoses for intramedullary lesions of the conus medullaris, both neoplastic and non-neoplastic. There is a limited role for surgery in a large proportion of these diagnoses, and operative risks can outweigh any benefits of surgery. Here a case is presented of a patient referred to a neurosurgical center for a biopsy of a presumed neoplastic conus tumor. However, through the collaboration of a multidisciplinary team, further diagnoses were considered. After thorough investigation, two conditions were diagnosed: venous congestive myelopathy secondary to inferior vena cava agenesis and spinal neurosarcoidosis...
July 2022: Journal of Neurological Surgery Reports
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