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https://www.readbyqxmd.com/read/28222560/depression-following-traumatic-brain-injury-impact-on-post-hospital-residential-rehabilitation-outcomes
#1
Frank D Lewis, Gordon J Horn
BACKGROUND: A need exists to better understand the impact of depression on functional outcomes following TBI. OBJECTIVES: To evaluate the prevalence and severity of depression among a large group of chronic TBI adults; to determine the impact of depression on outcomes of post-hospital residential rehabilitation programs; and to assess effectiveness of post-hospital residential rehabilitation programs in treating depression. METHODS: 820 adults with moderate to severe traumatic brain injury (TBI) were assigned to one of four groups based on MPAI- 4 depression ratings: (1) Not Depressed, (2) Mildly Depressed, (3) Moderately Depressed, and (4) Severely Depressed...
February 8, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28222119/revised-hammersmith-scale-for-spinal-muscular-atrophy-a-sma-specific-clinical-outcome-assessment-tool
#2
Danielle Ramsey, Mariacristina Scoto, Anna Mayhew, Marion Main, Elena S Mazzone, Jacqueline Montes, Roberto de Sanctis, Sally Dunaway Young, Rachel Salazar, Allan M Glanzman, Amy Pasternak, Janet Quigley, Elizabeth Mirek, Tina Duong, Richard Gee, Matthew Civitello, Gihan Tennekoon, Marika Pane, Maria Carmela Pera, Kate Bushby, John Day, Basil T Darras, Darryl De Vivo, Richard Finkel, Eugenio Mercuri, Francesco Muntoni
Recent translational research developments in Spinal Muscular Atrophy (SMA), outcome measure design and demands from regulatory authorities require that clinical outcome assessments are 'fit for purpose'. An international collaboration (SMA REACH UK, Italian SMA Network and PNCRN USA) undertook an iterative process to address discontinuity in the recorded performance of the Hammersmith Functional Motor Scale Expanded and developed a revised functional scale using Rasch analysis, traditional psychometric techniques and the application of clinical sensibility via expert panels...
2017: PloS One
https://www.readbyqxmd.com/read/28220090/adaptation-and-validation-of-a-chinese-version-of-patient-health-engagement-scale-for-patients-with-chronic-disease
#3
Yaying Zhang, Guendalina Graffigna, Andrea Bonanomi, Kai-Chow Choi, Serena Barello, Pan Mao, Hui Feng
The Patient Health Engagement Scale (PHE-s) was designed to assess the emotional and psychological attitudes of patients' engagement along their healthcare management journey. The aim of this study was to validate a culturally adapted Chinese version of the PHE-s (CPHE-s). Three hundred and seventy-seven participants were recruited from eight community health centers in a sample of patients with chronic disease in Hunan Province, China. The original Italian PHE-s was translated into Mandarin Chinese using a standardized forward-backward translation...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28207582/predictors-of-physician-assistant-faculty-intent-to-leave-academia-a-rasch-regression-analysis
#4
Svetlana Beltyukova, Karen Graham
PURPOSE: The purpose of this research was to investigate whether a previously developed and validated measure of intention to stay in academia for physician assistant (PA) faculty could also be used to inform PA faculty intent to leave academia and return to full-time clinical practice. METHODS: A secondary analysis of the national survey data of PA faculty (n = 427) was conducted using a Rasch regression model. The 19 items from the previously validated Supportive Environment Scale were examined as potential predictors of the dichotomous outcome of intent to leave academia...
March 2017: Journal of Physician Assistant Education
https://www.readbyqxmd.com/read/28196503/validation-of-the-generic-medical-interview-satisfaction-scale-the-g-miss-questionnaire
#5
Axel Maurice-Szamburski, Pierre Michel, Anderson Loundou, Pascal Auquier
BACKGROUND: Patients have about seven medical consultations a year. Despite the importance of medical interviews in the healthcare process, there is no generic instrument to assess patients' experiences in general practices, medical specialties, and surgical specialties. The main objective was to validate a questionnaire assessing patients' experiences with medical consultations in various practices. METHOD: The G-MISS study was a prospective multi-center trial that enrolled patients from May to July 2016...
February 14, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28193238/transient-ikk2-activation-in-astrocytes-initiates-selective-non-cell-autonomous-neurodegeneration
#6
Michael Lattke, Stephanie N Reichel, Alexander Magnutzki, Alireza Abaei, Volker Rasche, Paul Walther, Dinis P Calado, Boris Ferger, Thomas Wirth, Bernd Baumann
BACKGROUND: Neuroinflammation is associated with a wide range of neurodegenerative disorders, however the specific contribution to individual disease pathogenesis and selective neuronal cell death is not well understood. Inflammatory cerebellar ataxias are neurodegenerative diseases occurring in various autoimmune/inflammatory conditions, e.g. paraneoplastic syndromes. However, how inflammatory insults can cause selective cerebellar neurodegeneration in the context of these diseases remains open, and appropriate animal models are lacking...
February 13, 2017: Molecular Neurodegeneration
https://www.readbyqxmd.com/read/28192634/can-nursing-students-practice-what-is-preached-factors-impacting-graduating-nurses-abilities-and-achievement-to-apply-evidence-based-practices
#7
Ian R Blackman, Tracey M Giles
BACKGROUND: In order to meet national Australian nursing registration requisites, nurses need to meet competency requirements for evidence-based practices (EBPs). AIMS: A hypothetical model was formulated to explore factors that influenced Australian nursing students' ability and achievement to understand and employ EBPs related to health care provision. METHODS: A nonexperimental, descriptive survey method was used to identify self-reported EBP efficacy estimates of 375 completing undergraduate nursing students...
February 13, 2017: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/28179131/rasch-analysis-of-three-dry-eye-questionnaires-and-correlates-with-objective-clinical-tests
#8
Colm McAlinden, Rongrong Gao, Qinmei Wang, Senmiao Zhu, Jing Yang, Ayong Yu, Anthony J Bron, Jinhai Huang
PURPOSE: To assess the psychometric properties of Chinese versions of the Ocular Comfort Index (OCI), Ocular Surface Disease Index (OSDI) and McMonnies questionnaires. Further, to assess the correlation between questionnaire scores and objective dry eye disease (DED) clinical tests. METHODS: Translated versions of the OCI, OSDI and McMonnies questionnaires were completed in a random order by 238 participants with DED. Objective clinical tests included visual acuity (VA), fluorescein tear film break-up time (TBUT), corneal fluorescein staining, Schirmer I testing and meibomian gland grading...
February 4, 2017: Ocular Surface
https://www.readbyqxmd.com/read/28176419/quality-assessment-of-palliative-home-care-in-italy
#9
Gianlorenzo Scaccabarozzi, Pietro Giorgio Lovaglio, Fabrizio Limonta, Maddalena Floriani, Giacomo Pellegrini
RATIONALE: The complexity of end-of-life care, represented by a large number of units caring for dying patients, of different types of organizations motivates the importance of measure the quality of provided care. Despite the law 38/2010 promulgated to remove the barriers and provide affordable access to palliative care, measurement, and monitoring of processes of home care providers in Italy has not been attempted. AIMS AND OBJECTIVES: Using data drawn by an institutional voluntary observatory established in Italy in 2013, collecting home palliative care units caring for people between January and December 2013, we assess the degree to which Italian home palliative care teams endorse a set of standards required by the 38/2010 law and best practices as emerged from the literature...
February 7, 2017: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/28174467/comparison-of-the-psychometric-properties-of-two-balance-scales-in-children-with-cerebral-palsy
#10
Yong-Jin Jeon, Gyoung-Mo Kim
[Purpose] The purpose of this study was to compare the item difficulty degree between the Pediatric Balance Scale and Fullerton Advanced Balance scale for children with cerebral palsy. [Subjects and Methods] Forty children with cerebral palsy (male=17, female=23) voluntarily participated in the study. Item difficulty was expressed in the Rasch analysis using a logit value, with a higher value indicative of increasing item difficulty. [Results] Among the 24 items of the combined Pediatric Balance Scale and Fullerton Advanced Balance scale, the most difficult item was "Walk with head turns", whereas, the easiest item was "Sitting with back unsupported and feet supported on the floor"...
December 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28168833/childhood-cancer-predisposition-syndromes-a-concise-review-and-recommendations-by-the-cancer-predisposition-working-group-of-the-society-for-pediatric-oncology-and-hematology
#11
Tim Ripperger, Stefan S Bielack, Arndt Borkhardt, Ines B Brecht, Birgit Burkhardt, Gabriele Calaminus, Klaus-Michael Debatin, Hedwig Deubzer, Uta Dirksen, Cornelia Eckert, Angelika Eggert, Miriam Erlacher, Gudrun Fleischhack, Michael C Frühwald, Astrid Gnekow, Gudrun Goehring, Norbert Graf, Helmut Hanenberg, Julia Hauer, Barbara Hero, Simone Hettmer, Katja von Hoff, Martin Horstmann, Juliane Hoyer, Thomas Illig, Peter Kaatsch, Roland Kappler, Kornelius Kerl, Thomas Klingebiel, Udo Kontny, Uwe Kordes, Dieter Körholz, Ewa Koscielniak, Christof M Kramm, Michaela Kuhlen, Andreas E Kulozik, Britta Lamottke, Ivo Leuschner, Dietmar R Lohmann, Andrea Meinhardt, Markus Metzler, Lüder H Meyer, Olga Moser, Michaela Nathrath, Charlotte M Niemeyer, Rainer Nustede, Kristian W Pajtler, Claudia Paret, Mareike Rasche, Dirk Reinhardt, Olaf Rieß, Alexandra Russo, Stefan Rutkowski, Brigitte Schlegelberger, Dominik Schneider, Reinhard Schneppenheim, Martin Schrappe, Christopher Schroeder, Dietrich von Schweinitz, Thorsten Simon, Monika Sparber-Sauer, Claudia Spix, Martin Stanulla, Doris Steinemann, Brigitte Strahm, Petra Temming, Kathrin Thomay, Andre O von Bueren, Peter Vorwerk, Olaf Witt, Marcin Wlodarski, Willy Wössmann, Martin Zenker, Stefanie Zimmermann, Stefan M Pfister, Christian P Kratz
Heritable predisposition is an important cause of cancer in children and adolescents. Although a large number of cancer predisposition genes and their associated syndromes and malignancies have already been described, it appears likely that there are more pediatric cancer patients in whom heritable cancer predisposition syndromes have yet to be recognized. In a consensus meeting in the beginning of 2016, we convened experts in Human Genetics and Pediatric Hematology/Oncology to review the available data, to categorize the large amount of information, and to develop recommendations regarding when a cancer predisposition syndrome should be suspected in a young oncology patient...
February 7, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28164330/quality-of-life-in-patients-with-genetic-neuromuscular-disease-questionnaire-rasch-validation-of-the-french-version-qol-gnmd
#12
Antoine Dany, Amandine Rapin, Brice Lavrard, Virginie Saoût, Christian Réveillère, Guillaume Bassez, Vincent Tiffreau, Yann Péréon, Sabrina Sacconi, Bruno Eymard, Moustapha Dramé, Damien Jolly, Jean-Luc Novella, Jean-Benoit Hardouin, François C Boyer
INTRODUCTION: Slowly-progressive, genetic neuromuscular diseases (gNMDs) often lead to important motor deficiencies and functional limitations. The QoL-gNMD is a new health-related quality of life questionnaire developed for these patients. The purpose of the present study was to validate the French version of the QoL-gNMD and to calibrate its measurement system. METHODS: Both the QoL-gNMD and a validated generic questionnaire (WHOQOL-BREF) were administered to patients...
February 6, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28160102/on-the-validity-of-repeated-assessments-in-the-umat-a-high-stakes-admissions-test
#13
David Andrich, Irene Styles, Annette Mercer, Ian B Puddey
The possibility that the validity of assessment is compromised by repeated sittings of highly competitive and high profile selection tests has been documented and is of concern to stake-holders. An illustrative example is the Undergraduate Medicine and Health Sciences Admission Test (UMAT) used by some medical and dental courses in Australia and New Zealand. The proficiencies of all applicants who sat the UMAT from one to four sittings between 2006 and 2012 were estimated on the same metric using the probabilistic Rasch model...
February 4, 2017: Advances in Health Sciences Education: Theory and Practice
https://www.readbyqxmd.com/read/28155713/t2-prepared-segmented-3d-gradient-echo-for-fast-t2-weighted-high-resolution-three-dimensional-imaging-of-the-carotid-artery-wall-at-3t-a-feasibility-study
#14
Jian Zhu, Axel Bornstedt, Nico Merkle, Naifeng Liu, Wolfgang Rottbauer, Genshan Ma, Volker Rasche
BACKGROUND: The multi-contrast assessment of the carotid artery wall has become an important diagnostic tool for the characterization of atherosclerotic plaque and vessel wall thickening. For providing the required T1-, T2-, and proton density weighted contrast, multi-slice turbo spin echo (TSE) techniques are normally applied. The straightforward extension of the TSE techniques to volumetric imaging of large sections of the carotid arteries is limited by the resulting long acquisition times...
December 28, 2016: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28146443/developing-an-item-bank-to-measure-quality-of-life-in-individuals-with-glaucoma-and-the-results-of-the-interview-with-patients-the-effect-of-visual-function-visual-field-progression-rate-medical-and-surgical-treatments-on-quality-of-life
#15
Masato Matsuura, Kazunori Hirasawa, Hiroyo Hirasawa, Mieko Yanagisawa, Hiroshi Murata, Chihiro Mayama, Ryo Asaoka
PURPOSE: To construct a new item bank to measure quality of life (QOL) in glaucoma patients and to evaluate glaucoma patients' QOL using the item bank. METHODS: An item bank of questions was generated through a literature review of QOL instruments useful for glaucoma patients. Using this item bank, a cognitive survey was performed on 203 patients with glaucoma (112 males and 91 females, 61.9±11.9 y old; mean±SD). The results were then analyzed using the Rasch analysis, and the Rasch-derived disability scores were predicted using linear modelling and the following clinical parameters: age, mean total deviation (mTD) in superior and inferior visual field (mTDsup/mTDinf), mTD progression rate, better visual acuity, worse visual acuity, number of eye drops administered per day, number of trabeculectomy procedures experienced in both eyes...
February 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28143960/targeted-reactivation-during-sleep-differentially-affects-negative-memories-in-socially-anxious-and-healthy-children-and-adolescents
#16
S Groch, A Preiss, D McMakin, B Rasch, S Walitza, R Huber, I Wilhelm
: Cognitive models propose a negative memory bias as one key factor contributing to the emergence and maintenance of social anxiety disorder (SAD). The long-term consolidation of memories relies on memory reactivations during sleep. We investigated in SAD patients and healthy controls the role of memory reactivations during sleep in the long-term consolidation of positive and negative information. Socially anxious and healthy children and adolescents learnt associations between pictures showing ambiguous situations and positive or negative words defining the situations' outcome...
January 31, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28135739/-are-depressed-people-aggressive-people-differences-between-general-population-and-depressive-patients
#17
Stefanie Otte, Fabian U Lang, Nenad Vasic, Riad Shenar, Katharina Rasche, Charlotte Ramb, Manuela Dudeck, Judith Streb
IntroductionThe study aimed to investigate the relationship between depression and aggression. Material and Methods681 depressive and non-depressive subjects of the general population as well as 132 depressive patients completed the Beck Depression Inventory Revised (BDI-II) as well as the Short Questionnaire for Gathering Factors of Aggressiveness (K-FAF). ResultsDepressive patients and depressive subjects of the general population did not merely report the highest levels of self-aggressiveness but also reached the highest scores on the scales of reactive and proactive aggression, indicating a high level of externalizing aggressiveness...
January 2017: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/28135211/clinical-assessment-of-the-impact-of-pelvic-pain-on-women
#18
K Jane Chalmers, Mark J Catley, Susan F Evans, G Lorimer Moseley
We aimed to develop a questionnaire that assesses the impact of pelvic pain on women, regardless of diagnosis, that has high utility, sound psychometric performance, easy scoring, and high reliability. Two studies, with 3 separate cohorts, were undertaken. Both studies were completed online. Studies included women with self-reported pelvic pain. Women were eligible to participate regardless of whether their pelvic pain was undiagnosed, self-diagnosed, or diagnosed by a clinician. Study 1 used a 3-round "patient-as-expert" Delphi technique...
March 2017: Pain
https://www.readbyqxmd.com/read/28130934/response-style-analysis-with-threshold-and-multi-process-irt-models-a-review-and-tutorial
#19
Ulf Böckenholt, Thorsten Meiser
Two different item response theory model frameworks have been proposed for the assessment and control of response styles in rating data. According to one framework, response styles can be assessed by analysing threshold parameters in Rasch models for ordinal data and in mixture-distribution extensions of such models. A different framework is provided by multi-process item response tree models, which can be used to disentangle response processes that are related to the substantive traits and response tendencies elicited by the response scale...
February 2017: British Journal of Mathematical and Statistical Psychology
https://www.readbyqxmd.com/read/28129358/prevalence-risk-factors-and-impact-of-undiagnosed-visually-significant-cataract-the-singapore-epidemiology-of-eye-diseases-study
#20
Jacqueline Chua, Blanche Lim, Eva K Fenwick, Alfred Tau Liang Gan, Ava Grace Tan, Ecosse Lamoureux, Paul Mitchell, Jie Jin Wang, Tien Yin Wong, Ching-Yu Cheng
OBJECTIVE: To determine the prevalence, risk factors, and impact of undiagnosed visually significant cataract in an Asian population. METHODS: The Singapore Epidemiology of Eye Diseases is a population-based study where 8,697 adults of Malay, Indian, and Chinese ethnicities aged > 40 years were invited for an eye examination, including lens photograph, to establish cataract diagnosis. Visually significant cataract was defined by Wisconsin Cataract Grading System and a best-corrected visual acuity <20/40 with cataract as the primary cause of vision impairment...
2017: PloS One
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