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https://www.readbyqxmd.com/read/28629656/clinical-practice-points-for-diabetes-management-during-ramadan-fast
#1
REVIEW
Shaukat Sadikot, K Jothydev, A H Zargar, Jamal Ahmad, S R Arvind, Banshi Saboo
Diabetes management during Ramadan is very crucial from the patient perspective as it can present significant risk of hypoglycemia and death when proper care is not taken. Moreover, managing diabetes in fasting Ramadan patients require different mechanisms than the routine diabetes management and pose significant challenge to the health care practitioners. Here we set forth to review the available literature of various clinical trials and studies on different antidiabetic agents in the context of Ramadan. On the basis of available evidence, we suggest that gliclazide is effective and it could be safely recommended in type 2 diabetic patients fasting during Ramadan...
June 13, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28628237/wing-phosphorylation-is-a-major-functional-determinant-of-the-lrs14-type-biofilm-and-motility-regulator-abfr1-in-sulfolobus-acidocaldarius
#2
Lingling Li, Ankan Banerjee, Lisa Franziska Bischof, Hassan Ramadan Maklad, Lena Hoffmann, Anna-Lena Henche, Fabian Veliz, Wolfgang Bildl, Uwe Schulte, Alvaro Orell, Lars-Oliver Essen, Eveline Peeters, Sonja-Verena Albers
In response to a variety of environmental cues, prokaryotes can switch between a motile and a sessile, biofilm-forming mode of growth. The regulatory mechanisms and signaling pathways underlying this switch are largely unknown in archaea but involve small winged helix-turn-helix DNA-binding proteins of the archaea-specific Lrs14 family. Here, we study the Lrs14 member AbfR1 of Sulfolobus acidocaldarius. Small-angle X-ray scattering data are presented, which are consistent with a model of dimeric AbfR1 in which dimerization occurs via an antiparallel coiled coil as suggested by homology modeling...
June 19, 2017: Molecular Microbiology
https://www.readbyqxmd.com/read/28625120/the-effects-of-ramadan-fasting-on-the-spirometric-data-of-healthy-adult-males
#3
Imed Latiri, Siwar Sandid, Mohamed Amine Fennani, Mohamed Hadrich, Tasnim Masmoudi, Chiraz Maatoug, Makrem Zammit-Chatti, Karim Chamari, Helmi Ben Saad
The few studies carried out on the effects of Ramadan fasting (RF) on spirometric values present contradictory conclusions. This study aimed at assessing whether RF affects healthy adults' spirometric values. Twenty-nine nonsmoking healthy males ( M ± standard error of mean [ SEM] of age: 27 ± 1 years) who fasted during Ramadan (June 29-July 28, 2014) volunteered to the study. Three periods (before-Ramadan [June 23-25], mid-Ramadan [July 14-16] and after-Ramadan [August 11-14]) were selected for spirometry measurements that were consistently performed 5...
July 2017: American Journal of Men's Health
https://www.readbyqxmd.com/read/28620763/anticancer-efficacy-of-self-nanoemulsifying-drug-delivery-system-of-sunitinib-malate
#4
Saad M Alshahrani, Abdullah S Alshetaili, Ahmed Alalaiwe, Bader B Alsulays, Md Khalid Anwer, Ramadan Al-Shdefat, Faisal Imam, Faiyaz Shakeel
Sunitinib malate (SM) is reported as a weakly soluble drug in water due to its poor dissolution rate and oral bioavailability. Hence, in the current study, various "self-nanoemulsifying drug delivery systems (SNEDDS)" of SM were prepared, characterized and evaluated for the enhancement of its in vitro dissolution rate and anticancer efficacy. On the basis of solubilization potential of SM in various excipients, "Lauroglycol-90 (oil), Triton-X100 (surfactant) and Transcutol-P (cosurfactant)" were selected for the preparation of SM SNEDDS...
June 15, 2017: AAPS PharmSciTech
https://www.readbyqxmd.com/read/28610307/three-new-species-of-phytoseiid-mites-acari-phytoseiidae-from-bahia-state-brazil
#5
Adeilma Nascimento DE Carvalho, Aníbal Ramadan Oliveira, Poliane Sá Argolo, Francisco Ferragut
During a survey of predatory mites on cocoa cropping areas in Bahia State, north-eastern Brazil, three undescribed species of Phytoseiidae were collected on natural vegetation associated with crops. Typhlodromips baculiductus n. sp., Graminaseius bahiensis n. sp. and Typhlodromalus annulatus n. sp. are described and diagnosed. Comments on the boundary between the genera Amblydromalus Chant & McMurtry and Typhlodromalus Muma are also included.
May 26, 2017: Zootaxa
https://www.readbyqxmd.com/read/28609911/phytoseiid-mites-acari-phytoseiidae-associated-with-tropical-ornamental-plants-with-a-checklist-and-a-key-to-the-species-of-bahia-brazil
#6
Poliane Sá Argolo, Renata M Vital Santos, Maria A Leão Bittencourt, Aloyséia C DA Silva Noronha, Gilberto J DE Moraes, Anibal Ramadan Oliveira
Twenty-four papers refer to phytoseiid mites from different plant species in the state of Bahia, northeastern Brazil, but none of those refer to taxonomic surveys on ornamental plants. The aim of this study was to determine phytoseiids from tropical ornamentals in the southern coastal region of Bahia state, as well as to present a checklist and an identification key to the species recorded in that state. Samples were collected at eight localities of five municipalities. A total of seventeen species in nine genera was found on fifteen plant species of the families Costaceae, Heliconiaceae, Musaceae and Zingiberaceae...
May 1, 2017: Zootaxa
https://www.readbyqxmd.com/read/28609171/myocardial-performance-index-in-hypertensive-disorders-of-pregnancy-the-relationship-between-blood-pressures-and-angiogenic-factors
#7
Hadi Ramadan, Sarosh Rana, Ariel Mueller, Surichhya Bajracharya, Dongsheng Zhang, Saira Salahuddin, Rabab Nasim, Joana Lopes Perdigao, Mohammed Minhaj, Avery Tung, Zolt Arany, Sajid Shahul
OBJECTIVE: To study the association between cardiac function measured by myocardial performance index (MPI), blood pressures and angiogenic factors measured at the time of echocardiography in patients with and without hypertensive disorders of pregnancy (HDP). METHODS: We prospectively studied 189 pregnant women and evaluated whether changes in cardiac function observed on echocardiography were correlated with higher blood pressures and whether higher blood pressures were associated with antiangiogenic proteins (soluble fms-like tyrosine kinase, sFlt1; soluble endoglin, sEng)...
May 2017: Hypertension in Pregnancy
https://www.readbyqxmd.com/read/28606526/cross-linked-graphene-oxide-sheets-via-modified-extracted-cellulose-with-high-metal-adsorption
#8
Amr A Yakout, Ramadan H El-Sokkary, Mohamed A Shreadah, Omnia G Abdel Hamid
We have studied the extraction of Cu(II) and Pb(II) ions from different types of aqueous solution by novel cross-linked graphene oxide sheets by modified extracted cellulose. The novel sorbent cellulose was extracted from the mangrove trees (Avicennia marina) and it was then grafted with acrylamide and immobilized by ethylenediamine for cross-linking process. The cross-linked graphene oxide sheets were identified by means of FT-IR, SEM and XRD. The adsorption studies of synthesized sorbent was optimized. Langmuir and Freundlich models were used for establish sorption equilibria...
September 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28605496/validation-of-microbiological-testing-in-cardiovascular-tissue-banks-results-of-a-quality-round-trial
#9
Theo M M H de By, Carl McDonald, Susanne Süßner, Jill Davies, Wee Ling Heng, Ramadan Jashari, Ad J J C Bogers, Pieter Petit
OBJECTIVES: Surgeons needing human cardiovascular tissue for implantation in their patients are confronted with cardiovascular tissue banks that use different methods to identify and decontaminate micro-organisms. To elucidate these differences, we compared the quality of processing methods in 20 tissue banks and 1 reference laboratory. We did this to validate the results for accepting or rejecting tissue. We included the decontamination methods used and the influence of antibiotic cocktails and residues with results and controls...
June 12, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28588426/effects-of-ramadan-fasting-on-platelet-reactivity-in-diabetic-patients-treated-with-clopidogrel
#10
W Bouida, H Baccouche, M Sassi, Z Dridi, T Chakroun, I Hellara, R Boukef, M Hassine, F Added, R Razgallah, I Khochtali, S Nouira
BACKGROUND: The effects of Ramadan fasting (RF) on clopidogrel antiplatelet inhibition were not previously investigated. The present study evaluated the influence of RF on platelet reactivity in patients with high cardiovascular risk (CVR) in particular those with type 2 diabetes mellitus (DM). METHODS: A total of 98 stable patients with ≥2 CVR factors were recruited. All patients observed RF and were taking clopidogrel at a maintenance dose of 75 mg. Clinical findings and serum lipids data were recorded before Ramadan (Pre-R), at the last week of Ramadan (R) and 4 weeks after the end of Ramadan (Post-R)...
2017: Thrombosis Journal
https://www.readbyqxmd.com/read/28588159/ramadan-perspective-epidemiology-and-education-in-diabetes-rapeed-study
#11
N I Siddiqui, M Kamrul-Hasan, M A Hossain, P K Chanda, M A Bakar, M Rahman, M A Kader
Ramadan fasting is one of the five pillars of Islam and is obligatory for all healthy adult and adolescent Muslims. A significant number of patients with diabetes observe fasting during Ramadan. The objectives of this Ramadan Perspective Epidemiology and Education in Diabetes (RAPEED) study were to find out the current knowledge, attitude, and practices about Ramadan fasting among people with diabetes in Bangladesh. This retrospective cross-sectional study recruited 648 subjects with diabetes mellitus attending the Endocrinology outpatient department of a tertiary level hospital of Bangladesh within two months of the end of Ramadan in 2016...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28585345/genetic-screening-of-fecb-fecx-g-and-fecx-i-mutations-and-their-linkage-with-litter-size-in-barki-and-rahmani-sheep-breeds
#12
A S El-Seedy, N M Hashem, K M El-Azrak, Anm Nour El-Din, T A Ramadan, T A Taha, M H Salem
Characterization of fecundity genes offers the opportunity to improve production efficiency, and the consequent increase in litter size in livestock industry, through utilizing them in breeding programs. The main objective of this study was to detect the BMPR-IB, BMP15 and GDF9 gene mutations and to investigate whether these mutations are associated with litter size in Egyptian sheep breeds. To achieve this goal, 73 adult ewes representing Barki (n = 33) and Rahmani (n = 40) breeds were used. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) screening approach was used to detect the presence of FecB, FecX(G) and FecX(I) mutations in the two selected breeds...
June 5, 2017: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/28584599/the-role-of-insulin-therapy-in-correcting-hepcidin-levels-in-patients-with-type-2-diabetes-mellitus
#13
Driton Vela, Jovica Leshoski, Elizabeta S Gjorgievska, Nikola Hadzi-Petrushev, Muharrem Jakupaj, Ramadan B Sopi, Mitko Mladenov
OBJECTIVES: Iron overload can cause or contribute to the pathogenesis of type 2 diabetes mellitus (T2DM), but how the major parameters of iron metabolism change in different settings of diabetes are still unclear. The aim of this study was to determine the relationship between iron, ferritin, and hepcidin levels in diabetic patients and the effect of insulin treatment. METHODS: The study included 80 subjects, 60 with T2DM and 20 without (control group). Serum hepcidin, insulin, ferritin, and iron levels were determined as well as other clinical parameters...
May 2017: Oman Medical Journal
https://www.readbyqxmd.com/read/28579435/graphene-nanoparticles-as-osteoinductive-and-osteoconductive-platform-for-stem-cell-and-bone-regeneration
#14
Hoda Elkhenany, Shawn Bourdo, Silke Hecht, Robert Donnell, David Gerard, Ramadan Abdelwahed, Andersen Lafont, Karrer Alghazali, Fumiya Watanabe, Alexandru S Biris, David Anderson, Madhu Dhar
The potential of graphene-based nanoparticles (GNPs) has recently gained significant attention in biomedicine, especially in tissue engineering. In this study, we investigated the osteoinductive and osteoconductive effects of low oxygen content graphene (LOG) nanoparticles on adult mesenchymal stem cells (MSCs) in vitro and in vivo. We showed that adult goat MSCs were viable in the presence of 0.1 mg/mL LOG and retained their stem cell properties. A 3D scaffold made from agarose was used to encapsulate MSCs and LOG nanoparticles...
June 1, 2017: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/28577886/investigating-physiological-glucose-excursions-before-during-and-after-ramadan-in-adults-without-diabetes-mellitus
#15
Maria Pallayova, Hadeel B Zaghloul, Teresa Arora, Sopna M Choudhury, Omar M Omar, Odette L Chagoury, Shahrad Taheri
AIM: The study aimed to investigate physiological effects of Ramadan fasting on continuously monitored glucose levels in relation to Ramadan in young non-diabetic adults. METHODS: Continuous glucose monitoring was employed to measure interstitial glucose for several days 1-2weeks before Ramadan, in the middle of Ramadan, and 4-6weeks after Ramadan to assess glucose exposure and glucose variability. RESULTS: A total of 34,182 accurate glucose sensor readings and 438 capillary blood glucose values [mean absolute difference median (interquartile range) 8...
May 31, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28571621/hemodynamic-catecholamine-vasomotor-and-vascular-responses-determinants-of-myocardial-ischemia-during-mental-stress
#16
Muhammad Hammadah, Ayman Alkhoder, Ibhar Al Mheid, Kobina Wilmot, Nino Isakadze, Naser Abdulhadi, Danielle Chou, Malik Obideen, Wesley T O'Neal, Samaah Sullivan, Ayman Samman Tahhan, Heval Mohamed Kelli, Ronnie Ramadan, Pratik Pimple, Pratik Sandesara, Amit J Shah, Laura Ward, Yi-An Ko, Yan Sun, Irina Uphoff, Brad Pearce, Ernest V Garcia, Michael Kutner, J Douglas Bremner, Fabio Esteves, David S Sheps, Paolo Raggi, Viola Vaccarino, Arshed A Quyyumi
AIMS: Mental stress-induced myocardial ischemia (MSIMI) in patients with coronary artery disease (CAD) is associated with adverse cardiovascular outcomes. We aim to assess hemodynamic, neuro-hormonal, endothelial, vasomotor and vascular predictors of MSIMI. METHODS AND RESULTS: We subjected 660 patients with stable CAD to 99mTc sestamibi myocardial perfusion imaging at rest, with mental (speech task) and with conventional (exercise/pharmacological) stress. Endothelium-dependent flow-mediated dilation (FMD), microvascular reactivity [reactive hyperemia index (RHI)] and arterial stiffness [pulse wave velocity (PWV)] were measured at rest and 30-min after mental stress...
May 25, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28571516/nsaids-as-potential-treatment-option-for-preventing-amyloid-%C3%AE-toxicity-in-alzheimer-s-disease-an-investigation-by-docking-molecular-dynamics-and-dft-studies
#17
Faizul Azam, Nada Hussin Alabdullah, Hadeel Mohammed Ehmedat, Abdullah Ramadan Abulifa, Ismail Taban, Sreedevi Upadhyayula
Aggregation of amyloid beta (Aβ) protein considered as one of contributors in development of Alzheimer's disease (AD). Several investigations have identified the importance of non-steroidal anti-inflammatory drugs (NSAIDs) as Aβ aggregation inhibitors. Here, we have examined the binding interactions of 24 NSAIDs belonging to eight different classes, with Aβ fibrils by exploiting docking and molecular dynamics studies. Minimum energy conformation of the docked NSAIDs were further optimized by density functional theory (DFT) employing Becke's three-parameter hybrid model, Lee-Yang-Parr (B3LYP) correlation functional method...
June 15, 2017: Journal of Biomolecular Structure & Dynamics
https://www.readbyqxmd.com/read/28571008/microrna-200b-expression-in-the-vitreous-humor-of-patients-with-proliferative-diabetic-retinopathy
#18
Amir Ramadan Gomaa, Eman Tayae Elsayed, Reham Fadl Moftah
BACKGROUND: The role of microRNA (miRNA)-200b in the pathogenesis of proliferative diabetic retinopathy (PDR) has been studied in diabetic animal models. The aim of this study was to assess miRNA-200b expression in the vitreous of patients with PDR and to determine its correlation with vascular endothelial growth factor (VEGF), one of the pathogenic mechanisms in PDR. METHODS: Quantitative reverse transcription polymerase chain reaction was used to measure miRNA-200b expression in the vitreous from 29 eyes with PDR and 30 eyes with idiopathic macular holes (IMH; control group)...
June 2, 2017: Ophthalmic Research
https://www.readbyqxmd.com/read/28566976/health-education-to-diabetic-patients-before-the-start-of-ramadan-experience-from-a-teaching-hospital-in-dammam
#19
Rayyan M Al-Musally, Mais A Al-Sardi, Zainab A Al-Elq, Afnan H Elahi, Rawan K Alduhailan, Muslim A Al-Elq, Fatma A Zainuddin, Noura A Alsafar, Jannat A Altammar, Abdulmohsen H Al-Elq
BACKGROUND AND OBJECTIVE: Studies have shown that pre-Ramadan structured educational program for patients with diabetes mellitus (DM) is beneficial. In this study, our aim was to evaluate the degree of adherence of treating physicians to such programs and their influence on the patient's knowledge and behavior. MATERIALS AND METHODS: This cross-sectional study was carried out on adult patients with DM attending a university hospital, who were observed while fasting during Ramadan 1436/2015...
May 2017: Journal of Family & Community Medicine
https://www.readbyqxmd.com/read/28566972/to-what-extent-are-arab-pilgrims-to-makkah-aware-of-the-middle-east-respiratory-syndrome-coronavirus-and-the-precautions-against-it
#20
Meshaal S Alotaibi, Abdulaziz M Alsubaie, Khaled A Almohaimede, Turki A Alotaibi, Omar A Alharbi, Abdulrahman F Aljadoa, Abdulaziz H Alhamad, Mazin Barry
BACKGROUND: Approximately, 80% of the many cases of the Middle East respiratory syndrome coronavirus (MERS-CoV) confirmed worldwide were diagnosed in the Kingdom of Saudi Arabia (KSA). The risk of the disease spreading internationally is especially worrying given the role of KSA as the home of the most important Islamic pilgrimage sites. This means the need to assess Arab pilgrims' awareness of MERS-CoV is of paramount importance. MATERIALS AND METHODS: A cross-sectional study was carried out during Ramadan 2015 in the Holy Mosque in Makkah, Saudi Arabia...
May 2017: Journal of Family & Community Medicine
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