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https://www.readbyqxmd.com/read/28527166/consensus-on-initiation-and-intensification-of-premix-insulin-in-type-2-diabetes-management
#1
Viswanathan Mohan, Sanjay Kalra, Jothydev Kesavadev, Awadhesh Kumar Singh, Ajay Kumar, Ambika Gopalakrishnan Unnikrishnan, Rajeev Chawla, Jagat Jyoti Mukherjee, Rakesh Kumar Sahay, J S Kumar, Anil Bhoraskar, Arthur J Asirvatham, Jayanta Kumar Panda, Abdul Hamid Zargar, Ashok Kumar Das
INTRODUCTION: Premix insulin is the most commonly used insulin preparation in India. The first Indian premix guidelines were developed in 2009 and thereafter were updated in 2013. There is a need to revisit the Indian premix insulin guidelines, in view of emerging evidence and introduction of newer co-formulations. OBJECTIVE: The present consensus has been developed to evaluate available premix formulations, examine existing evidence related to premix formulations, and evolve consensus statement of recommendations on the topic...
April 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28526936/fingerprint-of-long-non-coding-rna-regulated-by-cyclic-mechanical-stretch-in-human-aortic-smooth-muscle-cells-implications-for-hypertension
#2
Laura-Eve Mantella, Krishna K Singh, Paul Sandhu, Crystal Kantores, Azza Ramadan, Nadiya Khyzha, Adrian Quan, Mohammed Al-Omran, Jason E Fish, Robert P Jankov, Subodh Verma
Emerging evidence suggests that long non-coding RNAs (lncRNAs) represent a cellular hub coordinating various cellular processes that are critical in health and disease. Mechanical stress triggers changes in vascular smooth muscle cells (VSMCs) that in turn contribute to pathophysiological changes within the vasculature. We sought to evaluate the role that lncRNAs play in mechanical stretch-induced alterations of human aortic smooth muscle cells (HASMCs). RNA (lncRNA and mRNA) samples isolated from HASMCs that had been subjected to 10 or 20% elongation (1 Hz) for 24 h were profiled with the Arraystar Human LncRNA Microarray V3...
May 19, 2017: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/28525195/-acute-colonic-diverticulitis-outcome-according-to-general-practice-management-prior-to-referral-and-criteria-predictive-of-complications-a-10-year-experience-in-a-university-hospital
#3
P Youatou, W Ngatchou, G Yondou, F Nde, P Mols, A S Ramadan, M Ngassa
INTRODUCTION: Ambulatory treatment of acute uncomplicated diverticulitis has been shown to be safe and effective by several recent studies. The aim of our study was to analyze the outcome of general practice management concerning the complications, the treatment modalities and the hospitalization duration during the first episode of acute diverticulitis. MATERIEL AND METHODS: A total of 176 medical files of patient presenting between January 2000 and December 2010 at the emergency department with a first episode of acute diverticulitis confirmed by an abdominal CT scan were analyzed...
2017: Revue Médicale de Bruxelles
https://www.readbyqxmd.com/read/28520766/transcriptomic-analysis-of-salt-stress-responsive-genes-in-rhazya-stricta
#4
Nahid H Hajrah, Abdullah Y Obaid, Ahmed Atef, Ahmed M Ramadan, Dhivya Arasappan, Charllotte A Nelson, Sherif Edris, Mohammed Z Mutwakil, Alawia Alhebshi, Nour O Gadalla, Rania M Makki, Madgy A Al-Kordy, Fotouh M El-Domyati, Jamal S M Sabir, Mohammad A Khiyami, Neil Hall, Ahmed Bahieldin, Robert K Jansen
Rhazya stricta is an evergreen shrub that is widely distributed across Western and South Asia, and like many other members of the Apocynaceae produces monoterpene indole alkaloids that have anti-cancer properties. This species is adapted to very harsh desert conditions making it an excellent system for studying tolerance to high temperatures and salinity. RNA-Seq analysis was performed on R. stricta exposed to severe salt stress (500 mM NaCl) across four time intervals (0, 2, 12 and 24 h) to examine mechanisms of salt tolerance...
2017: PloS One
https://www.readbyqxmd.com/read/28515228/nk1-1-cells-promote-sustained-tissue-injury-and-inflammation-after-trauma-with-hemorrhagic-shock
#5
Shuhua Chen, Rosemary A Hoffman, Melanie Scott, Joanna Manson, Patricia Loughran, Mostafa Ramadan, Anthony J Demetris, Timothy R Billiar
Various cell populations expressing NK1.1 contribute to innate host defense and systemic inflammatory responses, but their role in hemorrhagic shock and trauma remains uncertain. NK1.1(+) cells were depleted by i.p. administration of anti-NK1.1 (or isotype control) on two consecutive days, followed by hemorrhagic shock with resuscitation and peripheral tissue trauma (HS/T). The plasma levels of IL-6, MCP-1, alanine transaminase (ALT), and aspartate aminotransferase (AST) were measured at 6 and 24 h. Histology in liver and gut were examined at 6 and 24 h...
May 17, 2017: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/28513111/type-2-diabetic-patients-fasting-on-ramadan-in-israel
#6
Zaina Adnan
Fasting during Ramadan is not mandatory for diabetic patients, but the majority of type 2 diabetic patients insist on fasting despite the potential risks. These patients represent a challenge not only for themselves, but also for healthcare practitioners during this period. This review provides, for the first time, healthcare practitioners in Israel with guidelines and recommendations that fit the Muslim population for better management of diabetic patients who fast during Ramadan, taking into consideration recently published recommendations and therapies available in Israel...
May 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28509312/histological-immunohistochemical-and-ultrastructural-study-of-secondary-compressed-spinal-cord-injury-in-a-rat-model
#7
Wafaa S Ramadan, Ghada A Abdel-Hamid, Saleh Al-Karim, Aymn T Abbas
INTRODUCTION: Spinal cord injury (SCI) is a life-disrupting condition in which the first few days are the most critical. Secondary conditions remain the main causes of death for people with SCI. The response of different cell types to SCI and their role at different times in the progression of secondary degeneration are not well understood. The aim of this study was to study the histopathological changes of compressed spinal cord injury (CSCI) in a rat model. MATERIAL AND METHODS: Forty adult male Sprague-Dawley rats were divided into four groups...
2017: Folia Histochemica et Cytobiologica
https://www.readbyqxmd.com/read/28508355/neuroproteomics-studies-challenges-and-updates
#8
Naify Ramadan, Hussein Ghazale, Mohammad El-Sayyad, Mohamad El-Haress, Firas H Kobeissy
The Human Genome Project in 2003 has resulted in the complete sequence of ~99% of the human genome paving the road for the Human Proteome Project (HPP) assessing the full characterization of the translated protein map of the 20,300 protein-coding genes. Consequently, the emerging of the proteomics field has successfully been adopted as the method of choice for the proteome characterization. Proteomics is a term that is used to encompass multidisciplinary approaches combining different technologies that aim to study the entire spectrum of protein changes at a specific physiological condition...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28507649/managing-medications-during-ramadan-fasting
#9
Kelly Grindrod, Wasem Alsabbagh
No abstract text is available yet for this article.
May 2017: Canadian Pharmacists Journal: CPJ, Revue des Pharmaciens du Canada: RPC
https://www.readbyqxmd.com/read/28502133/t-regulatory-cells-response-to-allergen-specific-immunotherapy-in-patients-with-allergic-airway-diseases-a-prospective-study
#10
Raghdaa A Ramadan, Emad A Morad, Mohamed El-Shabrawy
Forkhead box P3 (FoxP3) T regulatory (Treg) cells modulate the immune system by blocking other types of T-cells. They maintain tolerance to self-antigens and help in inducing tolerance to foreign antigens. A deregulation of FoxP3 Tregs seems to play an important role in allergic disorders. The aim of this work was to study the response of FoxP3 Treg cells and their FoxP3 expression in patients, attending the Allergy Unit and the Chest Outpatient Clinic, Faculty of Medicine, Zagazig University, with allergic airway diseases, before and 1 year after receiving subcutaneous allergen specific immunotherapy (SIT)...
June 2016: Egyptian Journal of Immunology
https://www.readbyqxmd.com/read/28500437/an-evaluation-of-the-translation-of-continuing-education-into-diabetes-public-health-care-by-pharmacists
#11
Kerry Wilbur, Sara Shabana, Fatima Maraghi, Alaa ElMubark, Nadir Kheir
Background Pharmacists are assuming greater public health roles and partaking in continuing education to advance knowledge and skills necessary for the provision of this patient care. Objective We sought to determine what conditions in a Middle East context influence how community pharmacists actually incorporate new information into practice. Setting Community pharmacies in Qatar. Methods A continuing professional development (CPD) program regarding the management of fasting diabetes patients during Ramadan was developed and delivered...
May 12, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28492499/bioactive-natural-products-of-marine-sponges-from-the-genus-hyrtios
#12
REVIEW
Nourhan Hisham Shady, Ebaa M El-Hossary, Mostafa A Fouad, Tobias A M Gulder, Mohamed Salah Kamel, Usama Ramadan Abdelmohsen
Marine sponges are known as a rich source for novel bioactive compounds with valuable pharmacological potential. One of the most predominant sponge genera is Hyrtios, reported to have various species such as Hyrtios erectus, Hyrtios reticulatus, Hyrtios gumminae, Hyrtios communis, and Hyrtios tubulatus and a number of undescribed species. Members of the genus Hyrtios are a rich source of natural products with diverse and valuable biological activities, represented by different chemical classes including alkaloids, sesterterpenes and sesquiterpenes...
May 11, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28480773/new-gentle-wing-high-shear-granulator-impact-of-processing-variables-on-granules-and-tablets-characteristics-of-high-drug-loading-formulation-using-design-of-experiment-approach
#13
Mohamed H Fayed, Sayed I Abdel-Rahman, Fars K Alanazi, Mahrous O Ahmed, Hesham M Tawfeek, Ramadan I Al-Shdefat
The aim of this work was to study the application of design of experiment (DoE) approach in defining design space for granulation and tableting processes using a novel gentle-wing high shear granulator. According to quality-by-design (QbD) prospective, critical attributes of granules and tablets should be ensured by manufacturing process design. A face centered central composite design has been employed in order to investigate the effect of water amount (X1), impeller speed (X2), wet massing time (X3) and water addition rate (X4) as independent process variables on granules and tablets characteristics...
May 8, 2017: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/28480767/evaluation-of-tumor-necrosis-factor-alpha-serum-level-in-obese-and-lean-women-with-clomiphene-citrate-resistant-polycystic-ovary-disease
#14
Emaduldin Seyam, Momen Hasan, Eissa M Khalifa, Ahmad Ramadan, Enas Hefzy
OBJECTIVE: The aim of this work was to investigate the level of the serum level of tumor necrosis factor alpha (TNF-α) as an inflammatory biomarker in lean and obese women with polycystic ovary disease (PCOD), who are resistant to clomiphene citrate (CCR-PCOD). PATIENTS AND DESIGN: It is a case-controlled study, where 150 (n = 150) PCOD women (study group), who are resistant to clomiphene citrate (CCR-PCOD) had been recruited, in addition to 100 (n = 100) women with PCOD, who are not resistant to clomiphene citrate (NCCR-PCOD) as the first control group, and another 100 women (n = 100) fertile women with normal reproductive health, as the second control group...
May 8, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28472559/role-of-oxidative-stress-in-epithelial-ovarian-cancer-in-egyptian-patients
#15
Asmaa Ramadan, Reda Hemida, Ahmed Nowara, Laila A Eissa, Amal M El-Gayar
BACKGROUND: Ovarian cancer has the highest mortality rate amongst all gynecologic malignancies. 90% of the cases are epithelial ovarian cancer (EOC). Ovarian cancer associated with reduction in the serum level of antioxidants super oxide dismutase (SOD) and glutathione peroxidase (GPX) and increasing in the serum level of Malondialdehyde (MDA). OBJECTIVE: To find correlation between oxidative stress and epithelial ovarian cancer. METHODS: In this cross-sectional study fifty-six female patients with EOC, twenty four female patients with benign ovarian tumors and ten healthy females were included in the current research study where serum level of SOD, GPX and MDA were measured...
May 2017: Journal of Experimental Therapeutics & Oncology
https://www.readbyqxmd.com/read/28472471/successful-immunosuppressant-free-heterotopic-transplantation-of-tracheal-allografts-in-the-pig
#16
Julien De Wolf, Mathias Brieu, Christophe Zawadzki, Alexandre Ung, Eric Kipnis, Ramadan Jashari, Thomas Hubert, Pierre Fayoux, Christophe Mariette, Marie-Christine Copin, Alain Wurtz
OBJECTIVES: It has been demonstrated that both heterotopic and orthotopic transplants of epithelium-denuded cryopreserved tracheal allografts are feasible in immunosuppressant-free rabbits. Validation of these results in large animals is required before considering clinical applications. We evaluated the viability, immune tolerance and strain properties of such tracheal allografts heterotopically transplanted in a pig model. METHODS: Ten tracheal segments, 5 short (5 rings) and 5 long (10 rings), were obtained from male Landrace pigs...
May 2, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28457505/evaluation-of-the-medial-clavicular-epiphysis-according-to-the-schmeling-and-kellinghaus-method-in-living-individuals-a-retrospective-ct-study
#17
Selma Uysal Ramadan, Murat Serdar Gurses, Nursel Turkmen Inanir, Cigdem Hacifazlioglu, Recep Fedakar, Samil Hizli
The evaluation of the medial clavicular epiphysis via CT plays an important role in the determination of age, particularly the 19th and 22nd ages. Several authors have recommended the use of the Schmeling and Kellinghaus methods in conjunction in the evaluation of the medial clavicular epiphysis. The aim of this retrospective study was to evaluate thin section CT scan images of the medial clavicular epiphysis according to the Schmeling and Kellinghaus method, and to discuss the obtained data in the light of the literature...
March 2017: Legal Medicine
https://www.readbyqxmd.com/read/28452316/predictive-value-of-qt-dispersion-and-isolated-t-wave-inversion-in-lead-avl-for-early-detection-of-left-anterior-descending-coronary-artery-lesions
#18
Ramadan Ghaleb, Hossam Mansour
No abstract text is available yet for this article.
March 2017: Atherosclerosis. Supplements
https://www.readbyqxmd.com/read/28452315/pattern-of-risk-factors-and-management-strategies-in-patients-with-acute-coronary-syndrome-in-different-age-groups-and-sex-categories
#19
Hossam Mansour, Ashraf Reda, Morad Mena, Ramadan Ghaleb, Ahmed Elkersh
No abstract text is available yet for this article.
March 2017: Atherosclerosis. Supplements
https://www.readbyqxmd.com/read/28452313/immediate-effect-of-sublingual-isosorbide-dinitrate-in-patients-with-coronary-slow-flow-phenomenon-csfp
#20
Hossam Mansour, Hassan El Labban, Ramadan Ghaleb
No abstract text is available yet for this article.
March 2017: Atherosclerosis. Supplements
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