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https://www.readbyqxmd.com/read/28332241/toll-like-receptor-2-arg753gln-and-arg677trp-polymorphisms-and-susceptibility-to-pulmonary-and-peritoneal-tuberculosis
#1
Mohammed A Saleh, Mahmoud M Ramadan, Eman O Arram
Recent evidence suggests that toll-like receptor-2 (TLR2) is important for host defense against Mycobacterium tuberculosis (MTB). TLR2 polymorphisms have shown significant impact on susceptibility or resistance to tuberculosis (TB). This case-control study aims to determine the influence of TLR2 (Arg753Gln and Arg677Trp) polymorphisms on the susceptibility to develop pulmonary or peritoneal TB. Genotyping of TLR2 (Arg753Gln and Arg677Trp) polymorphisms was carried out on 52 patients with pulmonary TB, 44 patients with peritoneal TB, and 50 healthy controls using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP)...
March 23, 2017: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
https://www.readbyqxmd.com/read/28330661/association-between-high-sensitivity-cardiac-troponin-levels-and-myocardial-ischemia-during-mental-stress-and-conventional-stress
#2
Muhammad Hammadah, Ibhar Al Mheid, Kobina Wilmot, Ronnie Ramadan, Ayman Alkhoder, Malik Obideen, Naser Abdelhadi, Shuyang Fang, Ijeoma Ibeanu, Pratik Pimple, Heval Mohamed Kelli, Amit J Shah, Brad Pearce, Yan Sun, Ernest V Garcia, Michael Kutner, Qi Long, Laura Ward, J Douglas Bremner, Fabio Esteves, Paolo Raggi, David Sheps, Viola Vaccarino, Arshed A Quyyumi
OBJECTIVES: This study sought to investigate whether patients with mental stress-induced myocardial ischemia will have high resting and post-mental stress high-sensitivity cardiac troponin I (hs-cTnI). BACKGROUND: Hs-cTnI is a marker of myocardial necrosis, and its elevated levels are associated with adverse outcomes. Hs-cTnI levels may increase with exercise in patients with coronary artery disease. Mental stress-induced myocardial ischemia is also linked to adverse outcomes...
March 10, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28322488/surgical-glue-in-laparoscopic-sleeve-gastrectomy-an-initial-experience-and-cost-effectiveness-analysis
#3
Gregoire Mercier, Marcelo Loureiro, Vera Georgescu, El Mehdi Skalli, Marius Nedelcu, Mohamed Ramadan, Jean Michel Fabre, Patrick Lefebvre, David Nocca
RATIONALE, AIMS, AND OBJECTIVES: Laparoscopic sleeve gastrectomy (LSG) is one of the most common bariatric procedures. Gastric leaks and bleeding are the most frequent complications, associated with a high clinical and economic burden. The best method of staple line reinforcement in LSG is debated. Surgical glue is one of the options available. The aim of this study was to assess the safety, efficiency, and relative cost-effectiveness of surgical glue used to perform LSG in morbid obese adults as compared with standard stapling...
March 21, 2017: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/28314924/leptin-induces-osteoblast-differentiation-of-human-valvular-interstitial-cells-via-the-akt-and-erk-pathways
#4
Mickael Rosa, Camille Paris, Yoann Sottejeau, Delphine Corseaux, Emmanuel Robin, Madjid Tagzirt, Francis Juthier, Ramadan Jashari, Antoine Rauch, André Vincentelli, Bart Staels, Eric Van Belle, Sophie Susen, Annabelle Dupont
AIMS: Calcific aortic valve disease (CAVD) affects 2-6% of the population over 65 years, and age, gender, smoking, overweight, dyslipidemia, diabetes contribute to the development of this disease. CAVD results, in part, from the osteoblast differentiation of human valvular interstitial cells (VICs). This study aims to elucidate the effects of leptin on osteoblast phenotype of VICs and the signalling pathways involved. METHODS: Patients who underwent aortic valve replacement for CAVD (n = 43) were included in this study...
March 18, 2017: Acta Diabetologica
https://www.readbyqxmd.com/read/28306390/study-of-cases-of-child-sexual-abuse-referred-for-medico-legal-examination-in-cairo-and-giza-egypt-2007-2011
#5
Amany E Abd El Rahman, Sonya M S Azab, Mohamed Ramadan
Child sexual abuse is a complex problem that results in detrimental effects on its victims. This study aimed to investigate the pattern of child sexual abuse in cases referred for medico-legal examination in Cairo and Giza governorates in the period between 2007-2011. The study included 813 cases of child sexual abuse. Female gender was more predominant than male gender (52.8%, 4.29 cases), and adolescents were the most frequent age group identified as victims of sexual abuse (43.8%, 356 cases). All perpetrators were male and most of them were persons outside the victims' families (89...
March 17, 2017: Journal of Child Sexual Abuse
https://www.readbyqxmd.com/read/28302157/reliability-of-medical-records-in-diagnosing-inflammatory-breast-cancer-in-egypt
#6
Lynne Le, Catherine Schairer, Ahmed Hablas, Jane Meza, Shinobu Watanabe-Galloway, Mohamed Ramadan, Sofia D Merajver, Ibrahim A Seifeldin, Amr S Soliman
BACKGROUND: Inflammatory breast cancer (IBC) is a rare, aggressive breast cancer diagnosed clinically by the presence of diffuse erythema, peau d'orange, and edema that arise quickly in the affected breast. This study evaluated the validity of medical records in Gharbiah, Egypt in identifying clinical signs/symptoms of IBC. For 34 IBC cases enrolled in a case-control study at the Gharbiah Cancer Society and Tanta Cancer Center, Egypt (2009-2010), we compared signs/symptoms of IBC noted in medical records to those recorded on a standardized form at the time of IBC diagnosis by clinicians participating in the case-control study...
March 16, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28296573/the-adverse-effects-and-treatment-results-of-smoking-cessation-pharmacotherapy-during-fasting-non-fasting-state
#7
Sinem Iliaz, Seda Tural Onur, Mehmet Atilla Uysal, Efsun Gonca Uğur Chousein, Elif Tanriverdi, Belma Akbaba Bagci, Ayse Bahadir, Didem Gorgun Hattatoglu, Mediha Gonenc Ortakoylu, Sibel Yurt
BACKGROUND: Cigarette smoking is one of the most common addictions worldwide. Muslim smokers reduce the number of cigarettes they smoke during Ramadan due to the long fasting hours. OBJECTIVES: We aimed to share our experience in a smoking cessation clinic during Ramadan by analyzing the efficacy and adverse effects of once-daily dosing of bupropion or varenicline in a fasting group compared with conventional dosing in a non-fasting group. METHODS: We analyzed 57 patients who attended our smoking cessation clinic during Ramadan of 2014 and 2015, and at least one follow-up visit...
March 15, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28296467/comparison-of-insulin-pump-therapy-and-multiple-daily-injections-insulin-regimen-in-patients-with-type-1-diabetes-during-ramadan-fasting
#8
Reem Alamoudi, Maram Alsubaiee, Ali Alqarni, Yousef Saleh, Saleh Aljaser, Abdul Salam, Mohsen Eledrisi
INTRODUCTION: Fasting Ramadan carries a high risk for patients with type 1 diabetes (T1DM). Data on the optimum insulin regimen in these patients are limited. OBJECTIVES: To compare glucose profiles in patients with T1DM who use continuous subcutaneous insulin infusion (CSII) compared with those who use multiple daily injections (MDI) insulin regimen during Ramadan fast. The primary outcome was rates of hypoglycemia. Other outcomes included glycemic control, number of days needed to break fasting, and acute glycemic complications...
March 15, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28295294/catching-up-with-wonderful-women-the-women-are-wonderful-effect-is-smaller-in-more-gender-egalitarian-societies
#9
Kuba Krys, Colin A Capaldi, Wijnand van Tilburg, Ottmar V Lipp, Michael Harris Bond, C-Melanie Vauclair, L Sam S Manickam, Alejandra Domínguez-Espinosa, Claudio Torres, Vivian Miu-Chi Lun, Julien Teyssier, Lynden K Miles, Karolina Hansen, Joonha Park, Wolfgang Wagner, Angela Arriola Yu, Cai Xing, Ryan Wise, Chien-Ru Sun, Razi Sultan Siddiqui, Radwa Salem, Muhammad Rizwan, Vassilis Pavlopoulos, Martin Nader, Fridanna Maricchiolo, María Malbran, Gwatirera Javangwe, İdil Işık, David O Igbokwe, Taekyun Hur, Arif Hassan, Ana Gonzalez, Márta Fülöp, Patrick Denoux, Enila Cenko, Ana Chkhaidze, Eleonora Shmeleva, Radka Antalíková, Ramadan A Ahmed
Inequalities between men and women are common and well-documented. Objective indexes show that men are better positioned than women in societal hierarchies-there is no single country in the world without a gender gap. In contrast, researchers have found that the women-are-wonderful effect-that women are evaluated more positively than men overall-is also common. Cross-cultural studies on gender equality reveal that the more gender egalitarian the society is, the less prevalent explicit gender stereotypes are...
March 14, 2017: International Journal of Psychology: Journal International de Psychologie
https://www.readbyqxmd.com/read/28293966/anatomic-reconstruction-of-the-anterior-cruciate-ligament-of-the-knee-with-or-without-reconstruction-of-the-anterolateral-ligament
#10
Samir Abdulrazik Ibrahim, Emad Mureed Shohdy, Yousef Marwan, Sami Abdulghaffar Ramadan, Abdulrahman Khalid Almisfer, Mohammad Wagdy Mohammad, Wael Shoabe Abdulsattar, Shiref Khirat
BACKGROUND: Rotational instability of the knee remains an issue after anterior cruciate ligament (ACL) reconstruction. Hypothesis/Purpose: The purpose was to evaluate the subjective and objective outcomes of combined reconstruction of the ACL and anterolateral ligament (ALL) of the knee. The hypothesis was that favorable outcomes can be achieved with this surgical procedure compared with isolated anatomic reconstruction of the ACL. STUDY DESIGN: Randomized controlled trial; Level of evidence, 2...
February 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28291719/immunization-with-outer-membrane-proteins-oprf-and-opri-and-flagellin-b%C3%A2-protects-mice-from-pulmonary-infection-with-mucoid-and-nonmucoid-pseudomonas-aeruginosa
#11
Ramadan Hassan, Wael El-Naggar, Abeer M Abd El-Aziz, Mona Shaaban, Hany I Kenawy, Youssif M Ali
BACKGROUND: Pseudomonas aeruginosa is a Gram-negative opportunistic bacterium, which considered as a common cause of nosocomial infection and life-threatening complications in immunocompromized and cystic fibrosis patients. Here, we evaluate the protective effect of recombinant vaccines composed of outer membrane proteins OprF and OprI alone or in combination with flagellin B against mucoid and nonmucoid pseudomonas infection. METHODS: BALB/C mice were immunized subcutaneous using OprF and OprI with or without flagellin B and antibody titers were determined...
February 20, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28288870/tia-model-is-attainable-in-wistar-rats-by-intraluminal-occlusion-of-the-mca-for-10-min-or-shorter
#12
A Durukan Tolvanen, E Tatlisumak, E Pedrono, U Abo-Ramadan, T Tatlisumak
Transient ischemic attack (TIA) has received only little attention in the experimental research field. Recently, we introduced a TIA model for mice, and here we set similar principles for simulating this human condition in Wistar rats. In the model: 1) transient nature of the event is ensured, and 2) 24 h after the event animals are free from any sensorimotor deficit and from any detectable lesion by magnetic resonance imaging (MRI). Animals experienced varying durations of ischemia (5, 10, 12.5, 15, 25, and-30 min, n=6-8 per group) by intraluminal middle cerebral artery occlusion (MCAO)...
March 10, 2017: Brain Research
https://www.readbyqxmd.com/read/28287277/inhibitory-potential-of-strepthonium-a-against-shiga-toxin-production-in-enterohemorrhagic-escherichia-coli-ehec-strain-edl933
#13
Cheng Cheng, Srikkanth Balasubramanian, Agnes Fekete, Markus Krischke, Martin J Mueller, Ute Hentschel, Tobias A Oelschlaeger, Usama Ramadan Abdelmohsen
The production of shiga toxin (Stx) is a critical step in the establishment and progress of enterohemorrhagic Escherichia coli (EHEC) infections. The possible release of Stx from dead and dying bacteria, and the risk of resistance development have restricted the usage of antibiotics against EHEC. The chlorinated quaternary ammonium compound, strepthonium A, was isolated from the culture of Streptomyces sp. SBT345 that was cultivated from the Mediterranean sponge Agelas oroides. The structure was elucidated and confirmed by spectroscopic analyses including 1D and 2D NMR, ESI-HRMS, as well as ESI-HRMS(2)...
March 13, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28270713/empowerment-based-diabetes-self-management-education-to-maintain-glycemic-targets-during-ramadan-fasting-in-people-with-diabetes-who-are-on-conventional-insulin-a-feasibility-study
#14
Yara M Eid, Sahar I Sahmoud, Mona M Abdelsalam, Barbara Eichorst
OBJECTIVE: This study aims to assess the feasibility of promoting safe Ramadan fasting through diabetes self-management education (DSME) and to determine the effect of such education on hypoglycemic episodes. DESIGN AND METHODS: This prospective study included subjects attending Ramadan reinforcement sessions for participants in the Educational Program for People with Diabetes (EPPWD) at the Ain-Shams University Diabetes Center in Cairo, Egypt. The DSME sessions started 2-3 weeks before Ramadan and included one experimental fasting day during the first week and one during the second week...
February 2017: Diabetes Spectrum: a Publication of the American Diabetes Association
https://www.readbyqxmd.com/read/28270651/re-clinical-and-biochemical-parameters-of-hemodialysis-patients-before-and-during-the-islamic-ramadan-month
#15
Behzad Einollahi, Shima Shahyad, Aidin Lotfiazar
No abstract text is available yet for this article.
March 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/28255839/impact-of-dehydration-and-fasting-on-intraocular-pressure-and-corneal-biomechanics-measured-by-the-ocular-response-analyzer
#16
Betul Seher Uysal, Necati Duru, Umut Ozen, Mucella Arikan Yorgun, Emine Akcay, Mehtap Caglayan, Nurullah Cagil
PURPOSE: To investigate the effects of dehydration and fasting on the intraocular pressure (IOP) and corneal biomechanics during Ramadan in healthy subjects. METHODS: A total of 36 healthy fasting male volunteers with a mean age of 32.7 ± 5.1 years (range 28-38 years) were enrolled in the study. A Reichert Ocular Response Analyzer (ORA) was used to measure the corneal resistance factor (CRF), corneal hysteresis (CH), Goldman-correlated IOP (IOPg), and corneal-compensated IOP (IOPcc), additionally IOP with Goldmann applanation tonometer (IOP-GAT) was taken...
March 2, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28251084/the-vitreomacular-interface-in-different-types-of-age-related-macular-degeneration
#17
Mohamed Abd ElMonaem El-Hifnawy, Hisham Ali Ibrahim, Amir Ramadan Gomaa, Mohamed A Elmasry
AIM: To evaluate the vitreomacular interface in cases with wet age-related macular degeneration (AMD) and to compare them to eyes with dry AMD and normal eyes. METHODS: This was a cross-sectional comparative study that included 87 eyes with wet AMD, 42 eyes with dry AMD and 40 eyes without AMD as a control group. Optical coherence tomography (OCT) examination was performed for all patients to assess the vitreomacular interface. RESULTS: In the wet AMD group, 34...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28245815/fast-magnetic-resonance-spectroscopic-imaging-techniques-in-human-brain-applications-in-multiple-sclerosis
#18
REVIEW
Oun Al-Iedani, Jeannette Lechner-Scott, Karen Ribbons, Saadallah Ramadan
Multi voxel magnetic resonance spectroscopic imaging (MRSI) is an important imaging tool that combines imaging and spectroscopic techniques. MRSI of the human brain has been beneficially applied to different clinical applications in neurology, particularly in neurooncology but also in multiple sclerosis, stroke and epilepsy. However, a major challenge in conventional MRSI is the longer acquisition time required for adequate signal to be collected. Fast MRSI of the brain in vivo is an alternative approach to reduce scanning time and make MRSI more clinically suitable...
February 28, 2017: Journal of Biomedical Science
https://www.readbyqxmd.com/read/28239763/correlation-between-pre-ramadan-glycemic-control-and-subsequent-glucose-fluctuation-during-fasting-in-adolescents-with-type-1-diabetes
#19
B Afandi, W Kaplan, N Al Hassani, S Hadi, A Mohamed
BACKGROUND: Even though patients with type 1 diabetes mellitus (T1DM) are exempted from fasting, the vast majority elect to fast against the advice of their healthcare providers. We have previously reported the incidence of wide fluctuations in blood glucose (BG) along with "unrecognized" severe hypoglycemia during Ramadan fasting in adolescents with T1DM. This report compares the continuous glucose monitoring (CGM) data during fasting in adolescents with T1DM according to their Pre-Ramadan diabetes control...
February 26, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28236664/review-of-insulin-associated-hypoglycemia-and-its-impact-on-the-management-of-diabetes-in-south-east-asian-countries
#20
REVIEW
Su-Yen Goh, Zanariah Hussein, Achmad Rudijanto
Although the incidence of diabetes is rising in South East Asia, there is limited information regarding the incidence and manifestation of insulin-associated hypoglycemia. The aim of this review is to discuss what is currently known regarding insulin-associated hypoglycemia in South East Asia, including its known incidence and impact in the region, and how the South East Asian population with diabetes differs from other populations. We found a paucity of data regarding the incidence of hypoglycemia in South East Asia that has contributed to the adoption of Western guidelines...
February 25, 2017: Journal of Diabetes Investigation
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