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https://www.readbyqxmd.com/read/28318320/regular-use-of-acetaminophen-or-acetaminophen-codeine-combinations-and-prescription-of-rescue-therapy-with-non-steroidal-anti-inflammatory-drugs-a-population-based-study-in-primary-care
#1
Alfredo Vannacci, Niccolò Lombardi, Monica Simonetti, Diego Fornasari, Andrea Fanelli, Iacopo Cricelli, Claudio Cricelli, Pierangelo Lora Aprile, Francesco Lapi
Objective There are contrasting positions concerning the benefit-risk ratio of acetaminophen use for osteoarthritis (OA)-related pain. To clarify the effectiveness of acetaminophen or acetaminophen-codeine combinations according to their regimen of use, we evaluated whether being a regular user (adherent) of these medications decreased the occurrence of rescue therapy with non-steroidal anti-inflammatory drugs (NSAIDs). Methods Using the Health Search IMS Health Longitudinal Patient Database, we formed a cohort of patients aged ≥18 years and newly treated with acetaminophen or acetaminophen-codeine combinations for OA between January 1, 2001 and December 31, 2013...
March 20, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28317259/a-prospective-study-of-the-substance-use-and-mental-health-outcomes-of-young-adult-former-and-current-cannabis-users
#2
Edmund Silins, Wendy Swift, Tim Slade, Barbara Toson, Bryan Rodgers, Delyse M Hutchinson
INTRODUCTION AND AIMS: The extent to which young adult former cannabis users fare better than infrequent users is unclear. We investigated the association between cannabis use status at age 23 and substance use and mental health outcomes at age 27. DESIGN AND METHODS: Data were from the 20+ year cohort of the PATH Through Life Study. Lifetime cannabis users (n = 1410) at age 23 were classified as former/occasional/regular users. Multivariable logistic regression was used to estimate the association between cannabis use status at age 23 and six outcomes assessed at age 27...
March 20, 2017: Drug and Alcohol Review
https://www.readbyqxmd.com/read/28306386/perceived-discrimination-among-racial-and-ethnic-minority-drug-users-and-the-association-with-health-care-utilization
#3
Courtney McKnight, Martha Shumway, Carmen L Masson, Enrique R Pouget, Ashly E Jordan, Don C Des Jarlais, James L Sorensen, David C Perlman
People who use drugs (PWUDs) are at increased risk for several medical conditions, yet they delay seeking medical care and utilize emergency departments (EDs) as their primary source of care. Limited research regarding perceived discrimination and PWUDs' use of health care services exists. This study explores the association between interpersonal and institutional racial/ethnic and drug use discrimination in health care settings and health care utilization among respondents (N = 192) recruited from methadone maintenance treatment programs (36%), HIV primary care clinics (35%), and syringe exchange programs (29%) in New York City (n = 88) and San Francisco (n = 104)...
March 17, 2017: Journal of Ethnicity in Substance Abuse
https://www.readbyqxmd.com/read/28292795/primary-care-management-of-opioid-use-disorders-abstinence-methadone-or-buprenorphine-naloxone
#4
REVIEW
Anita Srivastava, Meldon Kahan, Maya Nader
OBJECTIVE: To advise physicians on which treatment options to recommend for specific patient populations: abstinence-based treatment, buprenorphine-naloxone maintenance, or methadone maintenance. SOURCES OF INFORMATION: PubMed was searched and literature was reviewed on the effectiveness, safety, and side effect profiles of abstinence-based treatment, buprenorphine-naloxone treatment, and methadone treatment. Both observational and interventional studies were included...
March 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28276722/non-steroidal-anti-inflammatory-drugs-and-blood-pressure-control-in-patients-treated-for-hypertension-results-from-the-swedish-primary-care-cardiovascular-database
#5
Charlotta Ljungman, Thomas Kahan, Linus Schiöler, Björn Wettermark, Kristina B Boström, Jan Hasselström, Per Hjerpe, Karin Manhem
PURPOSE: The aim of this observational cohort study was to investigate blood pressure level and the possibility to reach target blood pressure during concomitant use of NSAID in hypertensive patients. MATERIALS AND METHODS: From the Swedish primary care cardiovascular database (SPCCD) a cohort of 5463 patients (2007 to 2008) with at least one prescription of NSAID dispensed 6 months prior to the last blood pressure measurement were included. Clinical data were extracted from computerized medical records and linked to the Prescribed Drug Register...
February 13, 2017: Blood Pressure
https://www.readbyqxmd.com/read/28223891/what-should-we-tell-our-patients-about-marijuana-cannabis-indica-and-cannabis-sativa
#6
EDITORIAL
Joseph Pizzorno
With several states allowing medicinal use of marijuana and a growing number decriminalizing recreational use, many of our patients are using this herbal drug. Approximately 43% of US adults have tried marijuana, with 13% using it regularly. These users are seeking help from integrative medicine practitioners regarding safety. They are looking for advice based on research and clinical experience, not politics or philosophical bias. The major health problems caused by marijuana appear to be bronchial irritation, decreased motivation, learning difficulties, and injuries...
December 2016: Integrative Medicine
https://www.readbyqxmd.com/read/28184070/the-legal-and-moral-perceptions-of-clinical-and-non-clinical-undergraduates-regarding-substance-use-a-pilot-project
#7
J Puryer, A Rowley, J Saimbi, A Waylen
Introduction Heavy alcohol and illicit drug use has been documented amongst medical and dental professionals and educational programs have been developed to attempt to reduce such behaviour in clinical undergraduates. This pilot study aims to investigate the legal and moral perceptions of substance use in clinical and non-clinical undergraduates.Method A cross-sectional self-report questionnaire was administered to 107 clinical and non-clinical undergraduates to investigate their moral and legal perceptions of alcohol and illicit substance use...
February 10, 2017: British Dental Journal
https://www.readbyqxmd.com/read/28161577/motivations-for-new-psychoactive-substance-use-among-regular-psychostimulant-users-in-australia
#8
Rachel Sutherland, Raimondo Bruno, Amy Peacock, Simon Lenton, Allison Matthews, Caroline Salom, Paul Dietze, Kerryn Butler, Lucinda Burns, Monica J Barratt
BACKGROUND: Examine the motivations for new psychoactive substance (NPS) use amongst a sample of regular psychostimulant users (RPU) in Australia, and determine whether motivations differ across substances. METHOD: Data were obtained from 419 RPU interviewed for the 2014 Ecstasy and related Drugs Reporting System who reported lifetime NPS use. Based on the most recent NPS used, motivations for use were rated on an 11-point scale (0 'no influence'-10 'maximum influence')...
February 2, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28133890/characterization-of-new-users-of-cilostazol-in-the-uk-spain-sweden-and-germany
#9
Jordi Castellsague, Susana Perez-Gutthann, Brian Calingaert, Christine Bui, Cristina Varas-Lorenzo, Alejandro Arana, Alexandra Prados-Torres, Beatriz Poblador-Plou, Francisca Gonzalez-Rubio, Maria Giner-Soriano, Albert Roso-Llorach, Marie Linder, Anna Citarella, Oliver Scholle, Tilo Blenk, Edeltraut Garbe
PURPOSE: To describe the characteristics of new users of cilostazol in Europe with the aim to support the evaluation of its benefit/risk as used in regular clinical practice before the implementation of labeling changes recommended by the European Medicines Agency. METHODS: New users of cilostazol were identified in populations enrolled in five European health automated databases in the UK (The Health Improvement Network [THIN]), Spain (EpiChron cohort and Information System for the Improvement of Research in Primary Care [SIDIAP]), Sweden (National Registers), and Germany (German Pharmacoepidemiological Research Database [GePaRD]) between 2002 and 2012...
January 30, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/28120646/prevalence-and-the-associated-risk-factors-of-hiv-stis-and-hbv-among-men-who-have-sex-with-men-in-kunming-china
#10
Xiujie Zhang, Manhong Jia, Min Chen, Hongbing Luo, Huichao Chen, Wei Luo, Wanyue Zhang, Yanling Ma, Chaojun Yang, Yanling Yang, Xiaobin Zhang, Jie Dai, Lijuan Dong, William Cw Wong, Pengfei Zhao, Lin Lu
To investigate the prevalence and the associated risk factors of human immunodeficiency virus (HIV), hepatitis B virus (HBV) and sexually transmitted infections (STIs) among men who have sex with men (MSM) in Kunming, 300 MSM were recruited through community-based organizations between September 2014 and January 2015. The prevalence of HIV, HBsAg, syphilis, Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) were 17.0%, 7.7%, 11.3%, 18.2% and 13.2%, respectively. In the three different anatomic sites (urethra, rectum and pharynx), the prevalence of rectal CT was the highest (15...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28117061/development-of-alcohol-and-drug-use-in-youth-with-manic-symptoms
#11
Sarah McCue Horwitz, Amy Storfer-Isser, Andrea S Young, Eric A Youngstrom, H Gerry Taylor, Thomas W Frazier, L Eugene Arnold, Mary A Fristad, Boris Birmaher, Robert L Findling
OBJECTIVE: This analysis examined alcohol and drug use over a 6-year follow-up of children in the Longitudinal Assessment of Manic Symptoms (LAMS) study. METHOD: LAMS screened 6- to 12.9-year-old children visiting 9 child outpatient mental health (MH) clinics, using the Parent General Behavior Inventory 10-item mania scale. All children with scores ≥12 and a matched group with scores ≤12 were invited to enroll. Children were assessed every 6 months. Assessments included demographics, family, MH history, child diagnoses, child stress, and alcohol and drug use...
February 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28108701/willingness-to-use-and-have-sex-with-men-taking-hiv-pre-exposure-prophylaxis-prep-results-of-online-surveys-of-australian-gay-and-bisexual-men-2011-2015
#12
Martin Holt, Toby Lea, Heather-Marie Schmidt, Johann Kolstee, Jeanne Ellard, Dean Murphy, Hong-Ha Truong, John de Wit
OBJECTIVE: Assess willingness to use HIV pre-exposure prophylaxis (PrEP), support for others using it and willingness to have sex with partners using PrEP among Australian gay and bisexual men (GBM). METHODS: National, online cross-sectional surveys of Australian GBM were conducted in 2011, 2013 and 2015. Scales measuring support for and willingness to have sex with men using PrEP were developed in 2015 using factor analysis. Trends and associations with key measures were analysed using multivariate logistic regression...
January 20, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28088741/prevalence-and-correlates-of-fentanyl-contaminated-heroin-exposure-among-young-adults-who-use-prescription-opioids-non-medically
#13
Alexandria Macmadu, Jennifer J Carroll, Scott E Hadland, Traci C Green, Brandon D L Marshall
BACKGROUND: The rate of overdose deaths caused by fentanyl-contaminated heroin (FCH) use is increasing rapidly in the United States. We examined risk factors for exposure to FCH and experiences with FCH use among young adult non-medical prescription opioids (NMPO) users. METHODS: We analyzed data from the Rhode Island Young Adult Prescription Drug Study (RAPiDS), which enrolled young adults aged 18 to 29 reporting prior 30day NMPO use between January 2015 and February 2016...
May 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28013479/idling-in-mao-s-shadow-heroin-addiction-and-the-contested-therapeutic-value-of-socialist-traditions-of-laboring
#14
Nicholas Bartlett
The Chinese government has come under attack by international critics for forcing drug users to labor in the name of treatment. While joining these activists in criticizing conditions in compulsory labor centers, former detainees who congregated at a drop-in center in southern Yunnan also defended the therapeutic potential of socialist legacies of laboring. Shuttling between laboring in state compulsory centers and idling in a market economy, long-term heroin users saw their difficulties in recovering from addiction as inextricably linked to their inability to find suitable work opportunities...
December 24, 2016: Culture, Medicine and Psychiatry
https://www.readbyqxmd.com/read/28012825/detection-of-the-antipsychotic-drug-quetiapine-in-the-blood-urine-and-hair-samples-of-the-victim-of-a-drug-facilitated-sexual-assault
#15
Sys Stybe Johansen
A drug rape facilitated with the sedative antipsychotic drug quetiapine is presented here. A teenage girl and her girlfriend went to the home of an adult couple they had met at a bar. Here, the teenage girl (victim) felt tired after consuming some alcoholic drinks and fell asleep. While she was asleep, the others left her at the house alone and returned to the bar. Later, the girl woke up to witness the adult male having intercourse with her, but she was not able to resist the attack. She fell asleep again and slept through the next day and a half, after which she left the house...
December 15, 2016: Forensic Science International
https://www.readbyqxmd.com/read/28001962/benzodiazepine-dependence-among-young-adult-participants-in-the-club-scene-who-use-drugs
#16
Steven P Kurtz, Mance E Buttram, Hilary L Surratt
Young adults ages 18-29 report the highest rates of benzodiazepine (BZD) misuse in the United States. The majority of club drug users are also in this age group, and BZD misuse is prevalent among participants in club scenes. This article examines BZD dependence and its correlates among young adult participants in the electronic dance music (EDM) culture in Miami, Florida, who use drugs. Structured interviews were with men and women (N = 356) ages 18 to 29 who reported regular attendance at EDM venues and recent use of both club drugs and BZDs...
January 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28001458/similarity-and-difference-in-drug-addiction-process-between-heroin-and-methamphetamine-dependent-users
#17
Ziyun Wang, Wei-Xiu Li, Liu Zhi-Min
OBJECTIVES: This study aimed to compare the drug addiction process between Chinese heroin- and methamphetamine (MA)-dependent users via a modified 4-stage addiction model (experimentation, occasional use, regular use, and compulsive use). METHODS: A descriptive study was conducted among 683 eligible participants. In the statistical analysis, we selected 340 heroin- and 295 MA-dependent users without illicit drug use prior to onset of heroin or MA use. RESULTS: The addiction process of heroin-dependent users was shorter than that of MA-dependent users, with shorter transitions from the onset of drug-use to the first drug craving (19...
March 21, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/27999646/higher-rate-of-microscopic-hematuria-in-elderly-patients-who-take-regular-doses-of-aspirin-result-from-ahap-study
#18
Emadouddin Moudi, Seyed-Reza Hosseini, Ali Bijani
BACKGROUND: Aspirin is the most widely used drug in medicine for cardiovascular and as recently for its role in cancer prevention. Although the risk of bleeding events increased following regular use of aspirin, little is known about the association of aspirin and hematuria. The present study aimed to evaluate the association of regular aspirin use and microscopic hematuria in elderly. METHODS: In this study, we have extracted the data of elderly people who participated in Amirkola Health and Aging Project (AHAP) and taking regular doses of aspirin...
2016: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/27986878/nonsteroidal-anti-inflammatory-drugs-and-endometrial-carcinoma-mortality-and-recurrence
#19
Theodore M Brasky, Ashley S Felix, David E Cohn, D Scott McMeekin, David G Mutch, William T Creasman, Premal H Thaker, Joan L Walker, Richard G Moore, Shashikant B Lele, Saketh R Guntupalli, Levi S Downs, Christa I Nagel, John F Boggess, Michael L Pearl, Olga B Ioffe, Kay J Park, Shamshad Ali, Louise A Brinton
BACKGROUND: Recent data suggest that the use of nonsteroidal anti-inflammatory drugs (NSAIDs) may be associated with reductions in endometrial cancer risk, yet very few have examined whether their use is related to prognosis among endometrial cancer patients. METHODS: Study subjects comprised 4374 participants of the NRG Oncology/Gynecology Oncology Group 210 Study with endometrial carcinoma who completed a presurgical questionnaire that assessed history of regular prediagnostic NSAID use and endometrial cancer risk factors...
March 2017: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/27955825/possession-of-weapon-and-school-violence-among-adolescents-and-their-association-with-history-of-traumatic-brain-injury-substance-use-and-mental-health-issues
#20
Gabriela Ilie, Robert E Mann, Angela Boak, Hayley A Hamilton, Jürgen Rehm, Michael D Cusimano
PURPOSE: Assessment of the association between illegal possession of weapon and assault on school property among adolescents with and without a history of traumatic brain injury (TBI) while assessing risk factors for these outcomes. METHODS: Data were derived from the Centre for Addiction and Mental Health's 2013 Ontario Student Drug Use and Health Survey completed by students in grades 7-12 (ages 11-20). RESULTS: In this sample of 5478 adolescents, 6...
February 2017: Injury
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