Read by QxMD icon Read


Norma Cecilia Serrano-Díaz, Edna Magaly Gamboa-Delgado, Clara Lucía Domínguez-Urrego, Andrea Liliana Vesga-Varela, Sergio Eduardo Serrano-Gómez, Doris Cristina Quintero-Lesmes
Introducción. Cada vez son más los hallazgos sobre la relación entre las concentraciones de vitamina D en el ser humano y diversas condiciones clínicas. Hay una gran cantidad de estudios que informan sobre dicha asociación, especialmente con complicaciones obstétricas, incluidas la preeclampsia y la diabetes mellitus de la gestación, entre otras, pero sus resultados todavía no son definitivos, por lo que se requieren estudios de intervención de calidad que confirmen la relación de la vitamina D con dichos resultados...
May 1, 2018: Biomédica: Revista del Instituto Nacional de Salud
Federico Mecacci, Serena Ottanelli, Felice Petraglia
Hyperglycemia is one of the most common medical conditions that women encounter during pregnancy and it is due to gestational diabetes (GDM) in the majority of cases [1]. GDM is associated with a higher incidence of maternal morbidity in pregnancy in term of hypertensive disorders/preclampsia and higher rate of cesarean delivery but also with long-term risk of type 2 diabetes and cardiovascular disease. Pregnancy can therefore be considered a stress test; diagnosis of HIP can unmask a preexisting susceptibility and consequently a future risk for type 2 diabetes and can be a useful marker of future cardiovascular risk...
May 3, 2018: Diabetes Research and Clinical Practice
J Prakash, V C Ganiger
The incidence of acute kidney injury in pregnancy (P-AKI) has declined significantly over the last three decades in developing countries. However, it is still associated with significant fetomaternal mortality and morbidity. The diagnosis of P-AKI is based on the serum creatinine increase. The usual formulas for estimating glomerular filtration rate (GFR) are not validated in this population. The incidence of P-AKI with respect to total AKI cases has decreased in the last three decades from 25% in 1980s to 9% in 2000s at our centre...
July 2017: Indian Journal of Nephrology
Beatriz Escobar-Padilla, Limberg Darinel Gordillo-Lara, Horacio Martínez-Puon
BACKGROUND: Preterm birth is one of the biggest problems in obstetrics and gynecology, given that it has an incidence of 10-11%. The objective was to identify the risk factors associated with a preterm birth. METHODS: A retrospective, observational, transversal and analytic case-control study was made. All premature birth incidences were determined as study objects and controls were integrated with term deliveries. A sample size of 344 patients with a control per case was calculated...
July 2017: Revista Médica del Instituto Mexicano del Seguro Social
Anning Yang, Huiping Zhang, Yue Sun, Yanhua Wang, Xiaoming Yang, Xiaoling Yang, Hui Zhang, Wei Guo, Guangrong Zhu, Jue Tian, Yuexia Jia, Yideng Jiang
Inflammation and dysregulated lipid metabolism are involved in the pathogenesis of preeclampsia, and fatty acid binding protein 4 (FABP4) is known to regulate both inflammation and lipid metabolism. In the present study, we elucidated the role of FABP4 using in vitro and in vivo models of preclampsia. We found increased expression of FABP4 in the placenta of preeclamptic rats, which was further confirmed in HTR-8 cells, an extravillous trophoblast cell line, treated with L-NAME. Overexpression of FABP4 in HTR-8 cells resulted in upregulated expression of pro-inflammatory cytokines IL-6 and TNF-α, and increased lipid accumulation, suggesting that FABP4 plays a role in preeclampsia...
October 2016: Placenta
Miguel A Saavedra, Antonio Sánchez, Reyna Bustamante, Dafhne Miranda-Hernández, Jimena Soliz-Antezana, Pilar Cruz-Domínguez, Sara Morales, Luis J Jara
OBJECTIVE: To report our experience in maternal-fetal outcome in women with RA in a national medical referral center. METHODS: A retrospective analysis of the records of pregnant women with rheumatoid arthritis attending at a Pregnancy and Autoimmune Rheumatic Diseases Clinic was performed. Maternal-fetal outcomes such as disease activity, preclampsia/eclampsia, rate of live births, abortions, stillbirths, preterm birth, weeks of gestation, birth weight, congenital malformations and use of anti-rheumatic drugs were studied...
2015: Revista Médica del Instituto Mexicano del Seguro Social
Mukhamad Nooryanto
OBJECTIVES: Determine the usefulness and effectiveness of STOX1 in chromosome 10q22 as a biomarker of preeclampsia at an early stage. METHODS: This was a quantitative observational cross-sectional study of blood sample from pregnant women with preeclampsia (study group) and normotensive (control group) in the delivery room of Obstetrics and Gynecology Department Dr. Saiful Anwar Hospital Malang, and Physiology Laboratory Faculty of Medicine Brawijaya University during February to April 2013...
January 2015: Pregnancy Hypertension
B Jodeiry, M Heidarzadeh, S Sahmani-Asl, M Hoseini, H Javaherizadeh, S Eliasi, K Abedini
INTRODUCTION AND AIM: Intra-ventricular hemorrhage (IVH) is an important predictor of adverse neurodevelopmental outcome. IVH risk factor identification may conduct improvement of quality of care in neonatal intensive care units. The aim of the current study was to determine possible risk factors associated with IVH in VLBW neonates admitted in our hospital. PATIENTS AND METHODS: All neonates with birth weight below 1500 gr admitted to NICU. Cranial ultrasonography was done for premature neonates weighed <1000 g in 3 to 5 days and in 1 month again...
January 2012: Nigerian Journal of Medicine: Journal of the National Association of Resident Doctors of Nigeria
Mario Joaquín López-Carbajal, María Esther Manríquez-Moreno, Daniela Gálvez-Camargo, Evelia Ramírez-Jiménez
BACKGROUND: preeclampsia constitutes one of the main causes of maternal and perinatal morbidity and mortality. The aim was to identify the risk factors associated to the developmental of preeclampsia mild-moderate and severe, as well as the force of association of these factors in a hospital of second-level medical care. METHODOLOGY: study of cases and controls, a relation 1:1, in women withdrawn of the Service of Gynecology and Obstetrics during 2004 to 2007. Pregnant women with more than 20 weeks gestation were included...
September 2012: Revista Médica del Instituto Mexicano del Seguro Social
Katherine D Bortoff, Chunfang Qiu, Scott Runyon, Michelle A Williams, Rangan Maitra
BACKGROUND: Preeclampsia is a hypertensive disorder that complicates 3-7% of pregnancies. The development of preeclampsia has not been completely elucidated and current therapies are not broadly efficacious. The apelinergic system appears to be involved in hypertensive disorders and experimental studies indicate a role of this system in preeclampsia. Thus, an epidemiological evaluation of apelin protein concentration in plasma was conducted in case-control study of pregnant women. METHODS: Data and maternal plasma samples were collected from pregnant women with confirmed preeclampsia (n = 76) or normotensive controls (n = 79)...
2012: Hypertension in Pregnancy
Santo Monte
Preeclampsia (PE) is one of the most common diseases worldwide, complicating ~5% of all pregnancies.Although no major progress has been achieved in the treatment of PE, our ability to identify women at highrisk has increased considerably during the past decade.The early identification of patients with an increased risk for preeclampsia is therefore one of the most important goals in obstetrics. Today, several markers may offer the potential to be used, most likely in a combinatory analysis, as predictors or diagnostic tools...
July 2011: Journal of Prenatal Medicine
M C Paasche Roland, B Lorentzen, K Godang, T Henriksen
The aim was to determine plasma levels of sFlt-1 and sEng on the arterial and venous side of the uteroplacental circulation in preeclamptic patients and healthy controls. Preeclamptic patients had higher arterial concentrations than controls of sFlt-1 (17,450 vs. 5055 pg/ml, p = 0.003) and sEng (68.7 vs. 28.7 ng/ml, p = 0.003). In the preclampsia group sFlt-1 was higher in the uterine vein than in the radial artery (22,450 vs. 17,450 pg/ml, p = 0.005). We found no gradient for sEng. Our results support the hypothesis that excess sFlt-1 at least partly originates in placenta, while excess sEng appears to have a different origin...
March 2012: Placenta
D Mihu, N Costin, Carmen Mihaela Mihu, Ligia Daniela Blaga, Raluca Bogdana Pop
AIM: Determination by a high sensitivity technique of serum C-reactive protein (CRP), a sensitive marker of inflammation in women with preeclampsia compared to normal pregnancy and investigation of the relationship between CRP and the severity of the preeclamptic syndrome. MATERIAL AND METHOD: The study included 40 women with preeclampsia and 40 control subjects with normal pregnancies in the last trimester of pregnancy. The serum CRP concentration was determined using the universal high sensitivity immunoturbidimetric assay...
October 2008: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
J Zahumensky
UNLABELLED: The purpose of this study was to summarize the new published data on the Doppler flowmetry in preeclampsia. METHODS: We summarize the new published data on the Doppler flowmetry in uteroplacental, fetoplacental and fetal circulation in preeclampsia. The present review summarized the results of clinical research on the Doppler flowmetry in the screening of risk of preclampsia, in the diagnosis of preclampsia and in the fetal risk in preclampsia (Ref. 19)...
2009: Bratislavské Lekárske Listy
T Bouattar, H Hakim, H Rhou, L Benamar, R Bayahia, N Ouzeddoun
OBJECTIVE: Renal transplantation with a well-functioning graft leads to a rapid restoration of endocrine and sexual functions. The aim of this study was to examine our experience with pregnancies among renal transplant patients, particularly with regard to their impact on graft function. PATIENTS AND METHODS: We analyzed 10 pregnancies in 7 renal transplant recipients for long-term graft outcomes in terms of clinical and biological data. RESULTS: The mean patient age was 28...
June 2009: Transplantation Proceedings
D S Sarsam, M Shamden, R Al Wazan
INTRODUCTION: Our study aims to compare neonatal and maternal outcomes between expectant (or conservative) and aggressive (or immediate) management in cases with severe preclampsia remote from term. METHODS: This is a comparative study conducted at Al-Batool Teaching Hospital in Mosul City, Iraq, from April 2003 to August 2004. A total of 74 singleton pregnancies complicated by severe preeclampsia with gestational age of 24-34 weeks were studied during this period...
September 2008: Singapore Medical Journal
Azza Abo Senna, Magda Zedan, Gamal E Abd el-Salam, Ashraf I el-Mashad
AIM: The aim of this study was to evaluate whether maternal circulating adrenomedullin (AM) values in patients with preeclampsia are different from those in normotensive pregnant women at different gestational ages. SUBJECTS AND METHODS: In a prospective clinical study, 90 women aged 17 to 40 years old, were divided into 4 main groups: group I (45 women): Normotensive pregnant women at first trimester (15 women), second trimester (15 women), and third trimester (15 women) of pregnancies...
February 6, 2008: Medscape Journal of Medicine
Vesna Mandić, Zeljko Miković, Milan Dukić, Mladenko Vasiljević, Dejan Filimonović, Mirjana Bogavac
INTRODUCTION: Systemic vasoconstriction in preeclamptic patients increases vascular resistance, and is manifested by increased arterial blood flow velocity. The aim of the study is to evaluate if there is a change of Doppler indices in maternal medial cerbral artery (MCA) in severe preeclampsia due to: 1) severity of clinical symptoms, 2) the begining of eclamptic attack and 3) the application of anticonvulsive therapy. MATERIAL AND METHODS: A prospective clinical study included 92 pregnant women, gestational age 28-36 weeks...
January 2005: Medicinski Pregled
Alexandros Daponte, Hara Skentou, Konstantinos D Dimopoulos, Athanasios Kallitsaris, Ioannis E Messinis
BACKGROUND: Massive vulvar edema in a woman with preeclampsia preceded the development of massive ascites and impending eclampsia. CASE: A 17-year-old preeclamptic, primiparous woman was admitted with preeclampsia and massive vulvar edema. Other causes were excluded. The vulvar edema increased as the blood pressure and ascites increased, and a severe headache developed. Cesarean section for increasing preclampsia was performed. In the puerperium, the blood pressure improved and vulvar edema resolved...
November 2007: Journal of Reproductive Medicine
Peter W Kaplan, Errol R Norwitz, Elinor Ben-Menachem, Page B Pennell, Maurice Druzin, Julian N Robinson, Jacki C Gordon
Women with epilepsy (WWE) face particular challenges during their pregnancy. Among the several obstetric issues for which there is some concern and the need for further investigation are: the effects of seizures, epilepsy, and antiepileptic drugs on pregnancy outcome and, conversely, the effects of pregnancy and hormonal neurotransmitters on seizure control and antiepileptic drug metabolism. Obstetric concerns include preclampsia/eclampsia, preterm delivery, placental abruption, spontaneous abortion, stillbirth, and small-for-date babies in WWE whether or not they are taking antiepileptic drugs...
November 2007: Epilepsy & Behavior: E&B
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"