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https://www.readbyqxmd.com/read/28644680/exploring-the-factor-structure-of-the-social-cognition-and-object-relations-global-rating-method-support-for-two-and-three-factor-models
#1
Caleb J Siefert, Michelle Stein, Jenelle Slavin-Mulford, Greg Haggerty, Samuel J Sinclair, Danielle Funke, Mark A Blais
The Social Cognition and Object Relations Scales-Global Rating Method (SCORS-G) contains 8 scales for coding narrative content. This study explores the factor structure of this measure using college (n = 171), outpatient (n = 239), and inpatient (n = 78) samples. Participants told stories to the Thematic Apperception Test (TAT; Murray, 1943) cards. Stories were transcribed and coded by blind raters using the SCORS-G. Cases were randomly assigned to an exploratory or validation group. Exploratory factor analysis with the exploratory group suggested 2- and 3-factor models...
June 23, 2017: Journal of Personality Assessment
https://www.readbyqxmd.com/read/28623527/updating-the-evidence-of-the-interaction-between-clopidogrel-and-cyp2c19-inhibiting-selective-serotonin-reuptake-inhibitors-a-cohort-study-and-meta-analysis
#2
Katsiaryna Bykov, Sebastian Schneeweiss, Robert J Glynn, Murray A Mittleman, David W Bates, Joshua J Gagne
INTRODUCTION: We previously found that patients who initiate clopidogrel while treated with a cytochrome P450 (CYP) 2C19-inhibiting selective serotonin reuptake inhibitor (SSRI) have a higher risk of subsequent ischemic events than patients treated with other SSRIs. It is not known whether initiating an inhibiting SSRI while treated with clopidogrel will also increase risk of ischemic events. OBJECTIVE: The aim of this study was to assess clinical outcomes following initiation of a CYP2C19-inhibiting SSRI versus initiation of other SSRIs among patients treated with clopidogrel and to update existing evidence on the clinical impact of clopidogrel-SSRI interaction...
June 16, 2017: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/28622790/early-life-risk-factors-identified-for-owner-reported-feline-overweight-and-obesity-at-around-two-years-of-age
#3
E C Rowe, W J Browne, R A Casey, T J Gruffydd-Jones, J K Murray
Obesity is considered the second most common health problem in pet cats in developed countries. This study used prospective data from a longitudinal study of pet cats ('C.L.A.W.S.', www.bristol.ac.uk/vetscience/claws) to identify early-life risk factors for feline overweight/obesity occurring at around two years of age. Data were collected via five owner-completed questionnaires (for cats aged two-six months, six months, 12 months, 18 months and two years respectively) completed between May 2011 and April 2015...
August 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28618327/long-term-antipsychotic-and-benzodiazepine-use-and-brain-volume-changes-in-schizophrenia-the-northern-finland-birth-cohort-1966-study
#4
Sanna Huhtaniska, Erika Jääskeläinen, Tuomas Heikka, Jani S Moilanen, Heli Lehtiniemi, Jussi Tohka, José V Manjón, Pierrick Coupé, Lassi Björnholm, Hannu Koponen, Juha Veijola, Matti Isohanni, Vesa Kiviniemi, Graham K Murray, Jouko Miettunen
High doses of antipsychotics have been associated with loss in cortical and total gray matter in schizophrenia. However, previous imaging studies have not taken benzodiazepine use into account, in spite of evidence suggesting adverse effects such as cognitive impairment and increased mortality. In this Northern Finland Birth Cohort 1966 study, 69 controls and 38 individuals with schizophrenia underwent brain MRI at the ages of 34 and 43 years. At baseline, the average illness duration was over 10 years. Brain structures were delineated using an automated volumetry system, volBrain, and medication data on cumulative antipsychotic and benzodiazepine doses were collected using medical records and interviews...
May 20, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28617095/association-of-ankle-arthritis-score-with-need-for-revision-surgery
#5
Stephen Croft, Kevin J Wing, Timothy R Daniels, Mark Glazebrook, Peter Dryden, Alastair Younger, Murray J Penner, Jason M Sutherland
BACKGROUND: The Ankle Arthritis Score (AAS) is a new patient-reported outcome derived from the Ankle Osteoarthritis Scale (AOS). This study analyzed longitudinally collected data from a cohort of patients in the Canadian Orthopaedic Foot and Ankle Society (COFAS) Ankle Arthritis Study in order to evaluate whether the postoperative AAS is associated with need for revision surgery. METHODS: A multicenter, prospective, ankle-reconstruction study enrolled 653 ankles undergoing total ankle replacement (TAR) or ankle arthrodesis (AA)...
June 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/28571591/dietary-inflammatory-index-and-risk-of-reflux-oesophagitis-barrett-s-oesophagus-and-oesophageal-adenocarcinoma-a-population-based-case-control-study
#6
Nitin Shivappa, James R Hebert, Lesley A Anderson, Martha J Shrubsole, Liam J Murray, Lauren B Getty, Helen G Coleman
The dietary inflammatory index (DIITM) is a novel composite score based on a range of nutrients and foods known to be associated with inflammation. DII scores have been linked to the risk of a number of cancers, including oesophageal squamous cell cancer and oesophageal adenocarcinoma (OAC). Given that OAC stems from acid reflux and that the oesophageal epithelium undergoes a metaplasia-dysplasia transition from the resulting inflammation, it is plausible that a high DII score (indicating a pro-inflammatory diet) may exacerbate risk of OAC and its precursor conditions...
June 2, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28542740/plasma-micrornas-as-biomarkers-of-pancreatic-cancer-risk-in-a-prospective-cohort-study
#7
Eric J Duell, Leila Lujan-Barroso, Núria Sala, Samantha Deitz McElyea, Kim Overvad, Anne Tjonneland, Anja Olsen, Elisabete Weiderpass, Lill-Tove Busund, Line Moi, David Muller, Paolo Vineis, Dagfinn Aune, Giuseppe Matullo, Alessio Naccarati, Salvatore Panico, Giovanna Tagliabue, Rosario Tumino, Domenico Palli, Rudolf Kaaks, Verena A Katzke, Heiner Boeing, H B As Bueno-de-Mesquita, Petra H Peeters, Antonia Trichopoulou, Pagona Lagiou, Anastasia Kotanidou, Ruth C Travis, Nick Wareham, Kay-Tee Khaw, Jose Ramon Quiros, Miguel Rodríguez-Barranco, Miren Dorronsoro, María-Dolores Chirlaque, Eva Ardanaz, Gianluca Severi, Marie-Christine Boutron-Ruault, Vinciane Rebours, Paul Brennan, Marc Gunter, Ghislaine Scelo, Greg Cote, Stuart Sherman, Murray Korc
Noninvasive biomarkers for early pancreatic ductal adenocarcinoma (PDAC) diagnosis and disease risk stratification are greatly needed. We conducted a nested case-control study within the Prospective Investigation into Cancer and Nutrition (EPIC) cohort to evaluate prediagnostic microRNAs (miRs) as biomarkers of subsequent PDAC risk. A panel of eight miRs (miR-10a, -10b, -21-3p, -21-5p, -30c, -106b, -155 and -212) based on previous evidence from our group was evaluated in 225 microscopically confirmed PDAC cases and 225 controls matched on center, sex, fasting status and age/date/time of blood collection...
May 19, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28542256/maternal-depression-and-anxiety-disorders-mdad-and-child-development-a-manitoba-population-based-study
#8
Brenda Comaskey, Noralou P Roos, Marni Brownell, Murray W Enns, Dan Chateau, Chelsea A Ruth, Okechukwu Ekuma
OBJECTIVE: To examine the association between maternal depression and anxiety disorders (MDAD) and child development assessed during the kindergarten year. METHODS: Administrative data from several health and social databases in Manitoba, Canada, were used to study 18,331 mother-child pairs. MDAD over the period from one year prior to the child's birth to the kindergarten year was defined using physician diagnoses and filled prescriptions. Child development was assessed during the kindergarten year using the Early Development Instrument (EDI) which measures vulnerability across five domains of development...
2017: PloS One
https://www.readbyqxmd.com/read/28535445/correlates-of-muscle-dysmorphia-symptomatology-in-natural-bodybuilders-distinguishing-factors-in-the-pursuit-of-hyper-muscularity
#9
Lachlan Mitchell, Stuart B Murray, Matthew Hoon, Daniel Hackett, Tania Prvan, Helen O'Connor
Muscle dysmorphia (MD) is characterized by the pathological pursuit of muscularity and leanness, which includes eating- and exercise-related practices. The aim of this cross-sectional study was to identify correlations of MD symptomatology in natural bodybuilders. An online survey assessing diet, supplementation and training practices, and MD and eating disorder symptoms was completed by male bodybuilders with recent experience competing in a drug-tested competition. Sixty participants (age 29.6±7.1 years) completed the survey...
May 20, 2017: Body Image
https://www.readbyqxmd.com/read/28535332/interventions-for-treating-anxiety-after-stroke
#10
REVIEW
Peter Knapp, C Alexia Campbell Burton, John Holmes, Jenni Murray, David Gillespie, C Elizabeth Lightbody, Caroline L Watkins, Ho-Yan Y Chun, Sharon R Lewis
BACKGROUND: Approximately 20% of stroke patients experience clinically significant levels of anxiety at some point after stroke. Physicians can treat these patients with antidepressants or other anxiety-reducing drugs, or both, or they can provide psychological therapy. This review looks at available evidence for these interventions. This is an update of the review first published in October 2011. OBJECTIVES: The primary objective was to assess the effectiveness of pharmaceutical, psychological, complementary, or alternative therapeutic interventions in treating stroke patients with anxiety disorders or symptoms...
May 23, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28528126/emotional-intelligence-increases-over-time-a-longitudinal-study-of-australian-pre-registration-nursing-students
#11
Kim Foster, Judith Fethney, Heather McKenzie, Murray Fisher, Emily Harkness, Desirée Kozlowski
BACKGROUND: Emotional intelligence (EI) has been associated with positive outcomes for nursing students. Higher EI is associated with personal wellbeing and stress management, higher academic performance, stronger nursing leadership and practice performance, and greater patient safety. While there is an increasing body of evidence on nursing students' EI, there is minimal evidence on EI over time during pre-registration programs. OBJECTIVES: To measure EI in pre-registration nursing students from program commencement to conclusion to ascertain EI over time and examine the relationship between EI and academic performance...
May 15, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/28523245/impact-of-skeletal-divergence-on-oral-health-related-quality-of-life-and-self-reported-jaw-function
#12
Joseph Safwat Antoun, William Murray Thomson, Tony Raymond Merriman, Roberto Rongo, Mauro Farella
OBJECTIVE: To investigate the differences in oral health-related quality of life (OHRQoL) and self-reported jaw function between patients with hyperdivergent and normodivergent facial types. METHODS: Eighty patients with a distinctively hyperdivergent facial type (mandibular plane angle greater than 2 standard deviations, or 42°) and 80 controls were individually matched according to age, sex, ethnicity, and treatment stage. Data were collected using self-report questionnaires such as the Oral Health Impact Profile (OHIP-14) and Jaw Functional Limitation Scale (JFLS-8)...
May 2017: Korean Journal of Orthodontics
https://www.readbyqxmd.com/read/28516167/standardization-of-the-modified-rodnan-skin-score-for-use-in-clinical-trials-of-systemic-sclerosis
#13
Dinesh Khanna, Daniel E Furst, Philip J Clements, Yannick Allanore, Murray Baron, Lazlo Czirjak, Oliver Distler, Ivan Foeldvari, Masataka Kuwana, Marco Matucci-Cerinic, Maureen Mayes, Thomas Medsger, Peter A Merkel, Janet E Pope, James R Seibold, Virginia Steen, Wendy Stevens, Christopher P Denton
The modified Rodnan skin score (mRSS) is a measure of skin thickness and is used as a primary or secondary outcome measure in clinical trials of systemic sclerosis (scleroderma). This state-of-art review provides a historical perspective of the development of the mRSS, summarizes the performance of mRSS as an outcome measure, provides guidance on assessing mRSS, and makes recommendations for incorporation of the mRSS into clinical trials.
January 2017: Journal of Scleroderma and related Disorders
https://www.readbyqxmd.com/read/28515265/clinical-marker-for-alzheimer-disease-pathology-in-logopenic-primary-progressive-aphasia
#14
Lucia A A Giannini, David J Irwin, Corey T McMillan, Sharon Ash, Katya Rascovsky, David A Wolk, Vivianna M Van Deerlin, Edward B Lee, John Q Trojanowski, Murray Grossman
OBJECTIVE: To determine whether logopenic features of phonologic loop dysfunction reflect Alzheimer disease (AD) neuropathology in primary progressive aphasia (PPA). METHODS: We performed a retrospective case-control study of 34 patients with PPA with available autopsy tissue. We compared baseline and longitudinal clinical features in patients with primary AD neuropathology to those with primary non-AD pathologies. We analyzed regional neuroanatomic disease burden in pathology-defined groups using postmortem neuropathologic data...
May 17, 2017: Neurology
https://www.readbyqxmd.com/read/28506476/adherence-to-lipid-management-guidelines-is-associated-with-lower-mortality-and-major-adverse-limb-events-in-patients-undergoing-revascularization-for-chronic-limb-threatening-ischemia
#15
Thomas F X O'Donnell, Sarah E Deery, Jeremy D Darling, Katie E Shean, Murray A Mittleman, Gabrielle N Yee, Matthew R Dernbach, Marc L Schermerhorn
OBJECTIVE: The 2013 American College of Cardiology/American Heart Association lipid management guidelines recommend high-intensity statins for all patients ≤75 years old with chronic limb-threatening ischemia (CLTI) and moderate-intensity statins for CLTI patients >75 years old without contraindications or on dialysis, but these recommendations are based primarily on coronary and stroke data. We aimed to validate these guidelines in patients with CLTI and to assess current adherence to these recommendations...
May 12, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28490023/cord-blood-il-16-is-associated-with-3-year-neurodevelopmental-outcomes-in-perinatal-asphyxia-and-hypoxic-ischaemic-encephalopathy
#16
Caroline E Ahearne, Ruby Y Chang, Brian H Walsh, Geraldine B Boylan, Deirdre M Murray
Activation of the inflammatory pathway is increasingly recognized as an important mechanism of injury following neonatal asphyxia and encephalopathy. This process may contribute to the poor prognosis seen in some cases, despite therapeutic hypothermia. Our group has previously identified raised interleukin (IL)-6 and IL-16, measured in umbilical cord blood at birth, to be predictive of grade of hypoxic-ischaemic encephalopathy (HIE). Our aim in this study was to examine the ability of these cytokines to predict the 3-year neurodevelopmental outcome in the same cohort...
May 11, 2017: Developmental Neuroscience
https://www.readbyqxmd.com/read/28488913/relationship-between-pre-training-subjective-wellness-measures-player-load-and-rating-of-perceived-exertion-training-load-in-american-college-football
#17
Andrew D Govus, Aaron Coutts, Rob Duffield, Andrew Murray, Hugh Fullagar
PURPOSE: The relationship between pre-training subjective wellness, external and internal training load in American College football is unclear. This study examined the relationship between pre-training subjective wellness (sleep quality, muscle soreness, energy, wellness Z score) on 1) player load and 2) session rating of perceived exertion (s-RPE-TL) in American College footballers. METHODS: Subjective wellness (measured using 5-point, Likert scale questionnaires); external load (derived from global position systems [GPS] and accelerometry) and s-RPE-TL were collected during three typical training sessions per week for the second half of an American collegiate football season (eight weeks)...
May 10, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28482017/evaluation-of-nicotine-pharmacokinetics-and-subjective-effects-following-use-of-a-novel-nicotine-delivery-system
#18
Axel Teichert, Patrick Brossard, Loyse Felber Medlin, Larissa Sandalic, Mikael Franzon, Chris Wynne, Murray Laugesen, Frank Lüdicke
Introduction: Novel nicotine delivery systems represent an evolving part of the tobacco harm reduction strategy. The pharmacokinetic (PK) profile of nicotine delivered by P3L, a pulmonary nicotine delivery system, and its effects on smoking urges and craving relief in relation to Nicorette® inhalator were evaluated. Methods: This open-label, ascending nicotine levels study was conducted in 16 healthy smokers. Three different nicotine delivery levels, 50, 80, and 150 µg/puff delivered by the P3L system were evaluated consecutively on different days, after the use of the Nicorette® inhalator...
May 6, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28459622/respiratory-symptoms-items-from-the-copd-assessment-test-identify-ever-smokers-with-preserved-lung-function-at-higher-risk-for-poor-respiratory-outcomes-an-analysis-of-the-subpopulations-and-intermediate-outcome-measures-in-copd-study-cohort
#19
Carlos H Martinez, Susan Murray, R Graham Barr, Eugene Bleecker, Russell P Bowler, Stephanie A Christenson, Alejandro P Comellas, Christopher B Cooper, David Couper, Gerard J Criner, Jeffrey L Curtis, Mark T Dransfield, Nadia N Hansel, Eric A Hoffman, Richard E Kanner, Eric Kleerup, Jerry A Krishnan, Stephen C Lazarus, Nancy K Leidy, Wanda O'Neal, Fernando J Martinez, Robert Paine, Stephen I Rennard, Donald P Tashkin, Prescott G Woodruff, MeiLan K Han
RATIONALE: Ever-smokers without airflow obstruction scores greater than or equal to 10 on the COPD Assessment Test (CAT) still have frequent acute respiratory disease events (exacerbation-like), impaired exercise capacity, and imaging abnormalities. Identification of these subjects could provide new opportunities for targeted interventions. OBJECTIVES: We hypothesized that the four respiratory-related items of the CAT might be useful for identifying such individuals, with discriminative ability similar to CAT, which is an eight-item questionnaire used to assess chronic obstructive pulmonary disease impact, including nonrespiratory questions, with scores ranging from 0 to 40...
May 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28459401/-value-of-procalcitonin-on-predicting-the-severity-and-prognosis-in-patients-with-early-ards-a-prospective-observation-study
#20
Zhixin Yu, Musen Ji, Xiulan Hu, Jun Yan, Zhaochen Jin
OBJECTIVE: To investigate the value of procalcitonin (PCT) on predicting the severity and prognosis in patients with early acute respiratory distress syndrome (ARDS). METHODS: A prospective observation study was conducted. A total of 113 patients with ARDS undergoing mechanical ventilation admitted to intensive care unit (ICU) of Affiliated People's Hospital of Jiangsu University from October 2012 to April 2016 were enrolled. Based on oxygenation index (PaO2/FiO2), the patients were classified into mild, moderate, and severe groups according to Berlin Definition...
January 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
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