keyword
MENU ▼
Read by QxMD icon Read
search

murray score

keyword
https://www.readbyqxmd.com/read/27932489/psychometric-properties-of-the-irish-management-standards-indicator-tool
#1
S Boyd, R Kerr, P Murray
BACKGROUND: Work Positive is Ireland's national policy initiative to control work-related stress. Since the introduction of the UK Health and Safety Executive's Management Standards (MS) in 2004, a number of studies have been undertaken to assess the potential adaptation of the MS framework within Ireland. AIMS: To investigate the dimensionality, reliability and validity of the Irish version of the MS Indicator Tool (ROI-MSIT). METHODS: Between February 2011 and June 2014, we collected data from a wide range of public and private sector organizations that used the ROI-MSIT...
December 7, 2016: Occupational Medicine
https://www.readbyqxmd.com/read/27923830/a-myc-activity-signature-predicts-poor-clinical-outcomes-in-myc-associated-cancers
#2
MoonSun Jung, Amanda J Russell, Bing Liu, Joshy George, Pei Yan Liu, Tao Liu, Anna DeFazio, David D L Bowtell, Andre Oberthuer, Wendy B London, Jamie I Fletcher, Michelle Haber, Murray D Norris, Michelle J Henderson
Myc transcriptional activity is frequently deregulated in human cancers, but a Myc-driven gene signature with prognostic ability across multiple tumor types remains lacking. Here we selected 18 Myc-regulated genes from published studies of Myc family targets in epithelial ovarian cancer (EOC) and neuroblastoma. A Myc family activity score derived from the 18 genes was correlated to MYC/MYCN/MYCL1 expression in a panel of 35 cancer cell lines. The prognostic ability of this signature was evaluated in neuroblastoma, medulloblastoma, diffuse large B-cell lymphoma (DLBCL), and EOC microarray gene expression datasets using Kaplan-Meier and multivariate Cox-regression analyses, and was further validated in 42 primary neuroblastomas using qPCR...
December 6, 2016: Cancer Research
https://www.readbyqxmd.com/read/27918673/predictive-indicators-of-overuse-injuries-in-adolescent-endurance-athletes
#3
Daniel Martínez-Silván, Jaime Díaz-Ocejo, Andrew Murray
PURPOSE: To analyse the influence of training exposure and the utility of self-report questionnaires on predicting overuse injuries in adolescent endurance athletes. METHODS: 5 adolescent male endurance athletes (15.7 ± 1.4 yr) from a full-time sports academy answered 2 questionnaires (Recovery Cue; RC-q & Oslo Sports Trauma Research questionnaire; OSTRC-q) on a weekly basis for one season (37 wks) in order to detect (1) signs of overtraining and under-recovery (RC-q) and (2) early symptoms of lower limb injuries (OSTRC-q)...
December 5, 2016: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/27916819/the-nutritional-value-and-health-benefits-of-chickpeas-and-hummus
#4
REVIEW
Taylor C Wallace, Robert Murray, Kathleen M Zelman
The 2015-2020 Dietary Guidelines for Americans advocate for increasing vegetable intake and replacing energy-dense foods with those that are nutrient-dense. Most Americans do not eat enough vegetables, and particularly legumes, each day, despite their well-established benefits for health. Traditional hummus is a nutrient-dense dip or spread made from cooked, mashed chickpeas, blended with tahini, olive oil, lemon juice, and spices. Consumers of chickpeas and/or hummus have been shown to have higher nutrient intakes of dietary fiber, polyunsaturated fatty acids, vitamin A, vitamin E, vitamin C, folate, magnesium, potassium, and iron as compared to non-consumers...
November 29, 2016: Nutrients
https://www.readbyqxmd.com/read/27909032/midterm-outcomes-of-polyvinyl-alcohol-hydrogel-hemiarthroplasty-of-the-first-metatarsophalangeal-joint-in-advanced-hallux-rigidus
#5
Timothy R Daniels, Alastair S E Younger, Murray J Penner, Kevin J Wing, Sara Lyn Miniaci-Coxhead, Ellie Pinsker, Mark Glazebrook
BACKGROUND: Hallux rigidus is the most common arthritic condition of the foot. A randomized clinical trial of first metatarsophalangeal (MTP) joint hemiarthroplasty with a polyvinyl alcohol (PVA) hydrogel implant (Cartiva) demonstrated pain relief and functional outcomes equivalent to first MTP arthrodesis at 2 years postoperation, with no cases of implant fragmentation, wear, or bone loss. We prospectively determined 5-year outcomes of first MTP hemiarthroplasty with the PVA hydrogel implant...
November 30, 2016: Foot & Ankle International
https://www.readbyqxmd.com/read/27908689/pcsk9-genetic-variants-and-risk-of-type-2-diabetes-a-mendelian-randomisation-study
#6
Amand F Schmidt, Daniel I Swerdlow, Michael V Holmes, Riyaz S Patel, Zammy Fairhurst-Hunter, Donald M Lyall, Fernando Pires Hartwig, Bernardo Lessa Horta, Elina Hyppönen, Christine Power, Max Moldovan, Erik van Iperen, G Kees Hovingh, Ilja Demuth, Kristina Norman, Elisabeth Steinhagen-Thiessen, Juri Demuth, Lars Bertram, Tian Liu, Stefan Coassin, Johann Willeit, Stefan Kiechl, Karin Willeit, Dan Mason, John Wright, Richard Morris, Goya Wanamethee, Peter Whincup, Yoav Ben-Shlomo, Stela McLachlan, Jackie F Price, Mika Kivimaki, Catherine Welch, Adelaida Sanchez-Galvez, Pedro Marques-Vidal, Andrew Nicolaides, Andrie G Panayiotou, N Charlotte Onland-Moret, Yvonne T van der Schouw, Giuseppe Matullo, Giovanni Fiorito, Simonetta Guarrera, Carlotta Sacerdote, Nicholas J Wareham, Claudia Langenberg, Robert Scott, Jian'an Luan, Martin Bobak, Sofia Malyutina, Andrzej Pająk, Ruzena Kubinova, Abdonas Tamosiunas, Hynek Pikhart, Lise Lotte Nystrup Husemoen, Niels Grarup, Oluf Pedersen, Torben Hansen, Allan Linneberg, Kenneth Starup Simonsen, Jackie Cooper, Steve E Humphries, Murray Brilliant, Terrie Kitchner, Hakon Hakonarson, David S Carrell, Catherine A McCarty, H Lester Kirchner, Eric B Larson, David R Crosslin, Mariza de Andrade, Dan M Roden, Joshua C Denny, Cara Carty, Stephen Hancock, John Attia, Elizabeth Holliday, Martin O' Donnell, Salim Yusuf, Michael Chong, Guillaume Pare, Pim van der Harst, M Abdullah Said, Ruben N Eppinga, Niek Verweij, Harold Snieder, Tim Christen, Dennis O Mook-Kanamori, Stefan Gustafsson, Lars Lind, Erik Ingelsson, Raha Pazoki, Oscar Franco, Albert Hofman, Andre Uitterlinden, Abbas Dehghan, Alexander Teumer, Sebastian Baumeister, Marcus Dörr, Markus M Lerch, Uwe Völker, Henry Völzke, Joey Ward, Jill P Pell, Daniel J Smith, Tom Meade, Anke H Maitland-van der Zee, Ekaterina V Baranova, Robin Young, Ian Ford, Archie Campbell, Sandosh Padmanabhan, Michiel L Bots, Diederick E Grobbee, Philippe Froguel, Dorothée Thuillier, Beverley Balkau, Amélie Bonnefond, Bertrand Cariou, Melissa Smart, Yanchun Bao, Meena Kumari, Anubha Mahajan, Paul M Ridker, Daniel I Chasman, Alex P Reiner, Leslie A Lange, Marylyn D Ritchie, Folkert W Asselbergs, Juan-Pablo Casas, Brendan J Keating, David Preiss, Aroon D Hingorani, Naveed Sattar
BACKGROUND: Statin treatment and variants in the gene encoding HMG-CoA reductase are associated with reductions in both the concentration of LDL cholesterol and the risk of coronary heart disease, but also with modest hyperglycaemia, increased bodyweight, and modestly increased risk of type 2 diabetes, which in no way offsets their substantial benefits. We sought to investigate the associations of LDL cholesterol-lowering PCSK9 variants with type 2 diabetes and related biomarkers to gauge the likely effects of PCSK9 inhibitors on diabetes risk...
November 28, 2016: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/27908296/smoking-in-pregnancy-adolescent-mental-health-and-cognitive-performance-in-young-adult-offspring-results-from-a-matched-sample-within-a-finnish-cohort
#7
Hugh Ramsay, Jennifer H Barnett, Graham K Murray, Pirjo Mäki, Tuula Hurtig, Tanja Nordström, Jouko Miettunen, Vesa Kiviniemi, Solja Niemelä, Zdenka Pausova, Tomas Paus, Juha Veijola
BACKGROUND: The association between prenatal exposure to maternal cigarette smoking (PEMCS) and adult cognition is debated, including if there are differences according to sex. We aimed to determine if there are associations between PEMCS and cognition in early adulthood in men and women and examine if observed associations were mediated by adolescent mental health factors that are associated with cognition, namely psychotic-like experiences (PLEs), inattention and hyperactivity, and other externalizing behaviors...
December 1, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27906919/the-scratch-test-for-identifying-the-lower-liver-edge-is-at-least-as-accurate-as-percussion-and-is-significantly-more-effective-for-young-trainees-a-randomised-comparative-trial
#8
Alexander Huelsen, Jesse Fischer, Justin Hegarty, Anna Ashcroft, Christopher Ma Frampton, Murray L Barclay
BACKGROUND: Clinical examination of the liver requires experience to achieve accuracy. The scratch test is a simple technique to identify the lower liver edge and enhance liver palpation, and may be easier for trainees. AIM: We aimed to evaluate the accuracy of the scratch test compared to percussion at different levels of medical training. METHOD: Eight examiners, from trainee intern to consultant level, were randomised to scratch or percussion testing, followed by liver palpation, on 50 subjects...
December 2, 2016: New Zealand Medical Journal
https://www.readbyqxmd.com/read/27902568/health-utilities-in-people-with-chronic-pain-using-a-population-level-survey-and-linked-healthcare-administrative-data
#9
Mary-Ellen Hogan BScPhm, Anna Taddio BScPhm, Joel Katz, Vibhuti Shah, Murray Krahn
Health utilities are a preference-based measure of health-related quality of life that facilitates comparison of disease burden across conditions. We estimated utilities using a population-based, matched sample of adolescents and adults with and without chronic pain, controlling for comorbidity.Ontarians aged ≥12 years with and without chronic pain were identified from the Canadian Community Health Survey (CCHS) 2000-01 and 2009-10 and linked to their provincial healthcare administrative data. Individuals with chronic pain were matched to those without using age, sex, survey year, and a propensity score for having chronic pain estimated from a rurality index, income quintile and comorbidity...
November 24, 2016: Pain
https://www.readbyqxmd.com/read/27891820/investigating-diagnostic-bias-in-autism-spectrum-conditions-an-item-response-theory-analysis-of-sex-bias-in-the-aq-10
#10
Aja Louise Murray, Carrie Allison, Paula L Smith, Simon Baron-Cohen, Tom Booth, Bonnie Auyeung
Diagnostic bias is a concern in autism spectrum conditions (ASC) where prevalence and presentation differ by sex. To ensure that females with ASC are not under-identified, it is important that ASC screening tools do not systematically underestimate autistic traits in females relative to males. We evaluated whether the AQ-10, a brief screen for ASC recommended by the National Institute of Clinical Excellence in cases of suspected ASC, exhibits such a bias. Using an item response theory approach, we evaluated differential item functioning and differential test functioning...
November 28, 2016: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/27888683/lifetime-antipsychotic-medication-and-cognitive-performance-in-schizophrenia-at-age-43-years-in-a-general-population-birth-cohort
#11
Anja P Husa, Jani Moilanen, Graham K Murray, Riikka Marttila, Marianne Haapea, Irina Rannikko, Jennifer H Barnett, Peter B Jones, Matti Isohanni, Anne M Remes, Hannu Koponen, Jouko Miettunen, Erika Jääskeläinen
This naturalistic study analysed the association between cumulative lifetime antipsychotic dose and cognition in schizophrenia after an average of 16.5 years of illness. Sixty participants with schizophrenia and 191 controls from the Northern Finland Birth Cohort 1966 were assessed at age 43 years with a neurocognitive test battery. Cumulative lifetime antipsychotic dose-years were collected from medical records and interviews. The association between antipsychotic dose-years and a cognitive composite score based on principal component analysis was analysed using linear regression...
November 12, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27871708/treatment-associated-changes-in-malocclusion-and-oral-health-related-quality-of-life-a-4-year-cohort-study
#12
David L Healey, Robin D C Gauld, W Murray Thomson
INTRODUCTION: The impact of orthodontic treatment on oral health-related quality of life (OHRQoL) in adolescents being treated in orthodontic practices has not yet been explored longitudinally. The aim of this cohort study was to describe the changes in both malocclusion and OHRQoL with orthodontic treatment. METHODS: One hundred seventy-four patients (ages, 10-17 years; 64.4% girls; 81.6% European) underwent 2-arch, fixed-appliance treatment in a 4-year prospective study conducted across 19 specialist orthodontic practices throughout New Zealand...
November 2016: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/27864127/no-difference-between-latiglutenase-and-placebo-in-reducing-villous-atrophy-or-improving-symptoms-in-patients-with-symptomatic-celiac-disease
#13
Joseph A Murray, Ciarán P Kelly, Peter H R Green, Annette Marcantonio, Tsung-Teh Wu, Markku Mäki, Daniel C Adelman
BACKGROUND & AIMS: Gluten ingestion leads to symptoms and small intestinal mucosal injury in patients with celiac disease. The only option is the strict lifelong exclusion of dietary gluten, which is difficult to accomplish. Many patients following a gluten-free diet continue to have symptoms and have small intestinal mucosal injury. Non-dietary therapies are needed. We performed a phase 2 study of the ability of latiglutenase, an orally administered mixture of 2 recombinant gluten-targeting proteases, to reduce mucosal morphometric measures in biopsies from patients with celiac disease...
November 15, 2016: Gastroenterology
https://www.readbyqxmd.com/read/27863848/hypermobility-and-musculoskeletal-pain-in-adolescents
#14
Susan L Morris, Peter B O'Sullivan, Kevin J Murray, Natasha Bear, Beth Hands, Anne J Smith
OBJECTIVE: To determine the prevalence of generalized joint hypermobility (GJH) in a large cohort of Australian children and determine the associations between GJH and musculoskeletal pain. STUDY DESIGN: This is a cross-sectional analysis of the Western Australian Pregnancy Cohort (Raine) Study. Hypermobility was measured in 1584 participants at 14 years of age using the Beighton scoring system, along with a range of other factors including musculoskeletal pain status...
November 16, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27862526/systems-genetics-reveals-a-transcriptional-network-associated-with-susceptibility-in-the-maize-gray-leaf-spot-pathosystem
#15
Nanette Christie, Alexander A Myburg, Fourie Joubert, Shane L Murray, Maryke Carstens, Yao-Cheng Lin, Jacqueline Meyer, Bridget G Crampton, Shawn A Christensen, Jean F Ntuli, Sara S Wighard, Yves Van de Peer, Dave K Berger
We used a systems genetics approach to elucidate molecular mechanisms of maize responses to gray leaf spot (GLS) disease, caused by Cercospora zeina, a threat to maize production globally. Expression analysis of earleaf samples in a sub-tropical maize RIL population (CML444 X SC Malawi) subjected in field to C. zeina infection allowed detection of 20,206 expression QTLs (eQTL). Four trans-eQTL hotspots coincided with GLS disease QTLs mapped in the same field experiment. Co-expression network analysis identified three expression modules correlated with GLS disease scores...
November 12, 2016: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/27861859/cardiac-glycosides-and-breast-cancer-risk-a-systematic-review-and-meta-analysis-of-observational-studies
#16
Reema A Karasneh, Liam J Murray, Chris R Cardwell
Cardiac glycosides are phytoestrogens and have been linked to the risk of estrogen sensitive cancers such as uterus cancer. However, the association between use of cardiac glycosides and risk of breast cancer remains unclear. We investigated the association between cardiac glycosides use and the risk of breast cancer by systematically reviewing the published literature and performing meta-analyses. A comprehensive literature search was performed using MEDLINE, EMBASE, Web of Science and SCOPUS to identify all relevant articles published up to November 2015...
November 15, 2016: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/27859412/oesophageal-lichen-planus-the-efficacy-of-topical-steroid-based-therapies
#17
A Podboy, D Sunjaya, T C Smyrk, J A Murray, M Binder, D A Katzka, J A Alexander, M Halland
BACKGROUND: Oesophageal lichen planus is an idiopathic inflammatory disorder characterized by significant oesophageal stricturing. Oesophageal lichen planus is a rare, difficult to diagnose, and likely an under recognized disease. As a result, there is no standardized approach to therapy and treatment strategies vary. AIM: To examine the utility of topical steroid therapy (fluticasone or budesonide) in the management of oesophageal lichen planus. METHODS: A retrospective chart review was conducted of patients diagnosed with oesophageal lichen planus who underwent baseline and follow up endoscopy pre and post topical steroid therapy between 1995 and 2016 at Mayo Clinic, Rochester MN...
January 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27846814/lack-of-direct-evidence-for-natural-selection-at-the-candidate-thrifty-gene-locus-ppargc1a
#18
Murray Cadzow, Tony R Merriman, James Boocock, Nicola Dalbeth, Lisa K Stamp, Michael A Black, Peter M Visscher, Phillip L Wilcox
BACKGROUND: The gene PPARGC1A, in particular the Gly482Ser variant (rs8192678), had been proposed to be subject to natural selection, particularly in recent progenitors of extant Polynesian populations. Reasons include high levels of population differentiation and increased frequencies of the derived type 2 diabetes (T2D) risk 482Ser allele, and association with body mass index (BMI) in a small Tongan population. However, no direct statistical tests for selection have been applied. METHODS: Using a range of Polynesian populations (Tongan, Māori, Samoan) we re-examined evidence for association between Gly482Ser with T2D and BMI as well as gout...
November 15, 2016: BMC Medical Genetics
https://www.readbyqxmd.com/read/27810568/dignity-therapy-and-life-review-for-palliative-care-patients-a-randomized-controlled-trial
#19
Dean Vuksanovic, Heather J Green, Murray Dyck, Shirley A Morrissey
CONTEXT: Dignity therapy (DT) is a psychotherapeutic intervention with increasing evidence of acceptability and utility in palliative care settings. OBJECTIVES: The aim of this study was to evaluate the legacy creation component of DT by comparing this intervention with life review (LR) and waitlist control (WC) groups. METHODS: Seventy adults with advanced terminal disease were randomly allocated to DT, LR, or WC followed by DT, of which 56 completed the study protocol...
November 1, 2016: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/27791239/what-is-the-natural-history-of-asymptomatic-pseudotumours-in-metal-on-metal-hip-resurfacing-patients
#20
Gulraj S Matharu, Simon J Ostlere, Hemant G Pandit, David W Murray
PURPOSE: We assessed the natural history of asymptomatic pseudotumours associated with metal-on-metal hip resurfacings (MoMHRs), and factors associated with future revision. METHODS: In 2007-2008, we identified 25 MoMHRs (21 patients; mean age 59.9 years; 76% female) with asymptomatic pseudotumours. All patients underwent identical initial assessment (ultrasound, blood metal ions, radiographs, Oxford Hip Score [OHS]) and were considered asymptomatic because they denied experiencing hip symptoms, were satisfied with their MoMHR surgery, and had good or excellent OHSs (≥34)...
October 26, 2016: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
keyword
keyword
43296
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"