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https://www.readbyqxmd.com/read/29331695/depression-and-playfulness-in-fathers-and-young-infants-a-matched-design-comparison-study
#1
Vaheshta Sethna, Lynne Murray, Olivia Edmondson, Jane Iles, Paul G Ramchandani
BACKGROUND: Depression in fathers in the postnatal period is associated with an increased risk of some adverse child developmental outcomes. One possible mechanism for the familial transmission of risk is through the negative effects of depression on parenting and the parent-child relationship. So far, evidence indicates that depressed fathers tend to be more withdrawn in their early interactions. However, the interaction dimensions studied to date may not be able to detect and accurately classify unique features of father-infant play - including physically stimulating and highly rousing episodes of play...
January 3, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29331361/uterine-artery-embolization-an-analysis-of-online-patient-information-quality-and-readability-with-historical-comparison
#2
Timothy E Murray, Tayyaub Mansoor, Dermot J Bowden, Damien C O'Neill, Michael J Lee
RATIONALE AND OBJECTIVES: Investigators aimed to assess online information describing uterine artery embolization (UAE) to examine the quality and readability of websites patients are accessing. MATERIALS AND METHODS: A list of applicable, commonly used searchable terms was generated, including "Uterine Artery Embolization," "Fibroid Embolization," "Uterine Fibroid Embolization," and "Uterine Artery Embolisation." Each possible term was assessed across the five most-used English language search engines to determine the most commonly used term...
January 10, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29316357/cerebrovascular-events-in-systemic-lupus-erythematosus
#3
John G Hanly, Qiuju Li, Li Su, Murray B Urowitz, Caroline Gordon, Sang-Cheol Bae, Juanita Romero-Diaz, Jorge Sanchez-Guerrero, Sasha Bernatsky, Ann E Clarke, Daniel J Wallace, David A Isenberg, Anisur Rahman, Joan T Merrill, Paul Fortin, Dafna D Gladman, Ian N Bruce, Michelle Petri, Ellen M Ginzler, M A Dooley, Kristjan Steinsson, Rosalind Ramsey-Goldman, Asad A Zoma, Susan Manzi, Ola Nived, Andreas Jonsen, Munther A Khamashta, Graciela S Alarcón, Winn Chatham, Ronald F van Vollenhoven, Cynthia Aranow, Meggan Mackay, Guillermo Ruiz-Irastorza, Manuel Ramos-Casals, S Sam Lim, Murat Inanc, Kenneth C Kalunian, Soren Jacobsen, Christine A Peschken, Diane L Kamen, Anca Askanase, Chris Theriault, Vernon Farewell
OBJECTIVE: To determine the frequency, associations and outcomes of cerebrovascular events (CerVEs) in a multi-ethnic/racial, prospective, SLE disease inception cohort. METHODS: Patients were assessed annually for 19 neuropsychiatric (NP) events including 5 types of CerVEs: (i) Stroke; (ii) Transient ischemia; (iii) Chronic multifocal ischemia; (iv) Subarachnoid/intracranial hemorrhage; (v) Sinus thrombosis. Global disease activity (SLEDAI-2K), SLICC/ACR damage index (SDI) and SF-36 scores were collected...
January 5, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29290505/hand-therapists-attitudes-environmental-supports-and-self-efficacy-regarding-intimate-partner-violence-in-their-practice
#4
Marudan Sivagurunathan, Tara Packham, Lindsay Dimopoulos, Robyn Murray, Kim Madden, Joy C MacDermid
STUDY DESIGN: Descriptive, cross-sectional. INTRODUCTION: Intimate partner violence (IPV) may involve physical, psychological, or sexual abuse. Although hand injuries are reported as common sequelae of IPV, there is limited attention to this issue in hand therapy research reports or practice recommendations. PURPOSE OF THE STUDY: The primary aim is to describe the attitudes and beliefs of hand therapists (HTs) about IPV issues. METHODS: A sample of 189 HT completed a standardized survey investigating perceptions regarding issues pertaining to IPV...
December 29, 2017: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
https://www.readbyqxmd.com/read/29284438/randomised-control-trial-of-the-effectiveness-of-an-integrated-psychosocial-health-promotion-intervention-aimed-at-improving-health-and-reducing-substance-use-in-established-psychosis-impact
#5
Fiona Gaughran, Daniel Stahl, Khalida Ismail, Kathryn Greenwood, Zerrin Atakan, Poonam Gardner-Sood, Brendon Stubbs, David Hopkins, Anita Patel, John Lally, Philippa Lowe, Maurice Arbuthnot, Diana Orr, Sarah Corlett, Jonas Eberhard, Anthony S David, Robin Murray, Shubulade Smith
BACKGROUND: People with psychosis have a reduced life expectancy of 10-20 years, largely due to cardiovascular disease. This trial aimed to determine the effectiveness of a modular health promotion intervention (IMPaCT Therapy) in improving health and reducing cardiovascular risk in psychosis. METHODS: A multicentre, two arm, parallel cluster RCT was conducted across five UK mental health NHS trusts. Community care coordinators (CC) were randomly assigned to training and supervision in delivering IMPaCT Therapy or treatment as usual (TAU) to current patients with psychosis (cluster)...
December 28, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29261752/a-comparison-of-health-related-quality-of-life-hrqol-across-four-systemic-autoimmune-rheumatic-diseases-sards
#6
Julia Greenfield, Marie Hudson, Evelyne Vinet, Paul R Fortin, Vivian Bykerk, Christian A Pineau, Mianbo Wang, Sasha Bernatsky, Murray Baron
OBJECTIVES: To compare physical and mental health-related quality of life (HRQoL) across four systemic autoimmune rheumatic diseases (SARD). METHODS: Incident subjects enrolled in four SARD cohorts, namely systemic lupus erythematosus (SLE), systemic sclerosis (SSc), rheumatoid arthritis (RA) and idiopathic inflammatory myopathies (IIM) were studied. The outcomes of interest were baseline Short Form Health Survey physical (PCS) and mental (MCS) component summary scores...
2017: PloS One
https://www.readbyqxmd.com/read/29261691/do-experiences-and-perceptions-about-quality-of-care-differ-among-social-groups-in-nepal-a-study-of-maternal-healthcare-experiences-of-women-with-and-without-disabilities-and-dalit-and-non-dalit-women
#7
Hridaya Raj Devkota, Andrew Clarke, Emily Murray, Nora Groce
BACKGROUND: Suboptimal quality of care and disparities in services by healthcare providers are often reported in Nepal. Experience and perceptions about quality of care may differ according to women's socio-cultural background, individual characteristics, their exposure and expectations. This study aimed to compare perceptions of the quality of maternal healthcare services between two groups that are consistently considered vulnerable, women with disabilities from both the non-Dalit population and Dalit population and their peers without disabilities from both non-Dalit and Dalit communities...
2017: PloS One
https://www.readbyqxmd.com/read/29250574/rna-interference-screening-to-identify-proliferation-determinants-in-breast-cancer-cells
#8
Yong-Wei Zhang, Rochelle E Nasto, Sandra A Jablonski, Ilya G Serebriiskii, Rishi Surana, Joseph Murray, Michael Johnson, Rebecca B Riggins, Robert Clarke, Erica A Golemis, Louis M Weiner
RNAi screening technology has revealed unknown determinants of various biological signaling pathways in biomedical studies. This protocol provided detailed information about how to use RNAi screening to identify proliferation determinants in breast tumor cells. siRNA-based libraries targeting against Estrogen receptor (ER)-network, including 631 genes relevant to estrogen signaling, was constructed for screening in breast cancer cells. Briefly, reverse transfection of siRNA induced transient gene knockdown in MCF7 cells...
2017: Bio-protocol
https://www.readbyqxmd.com/read/29244891/the-effects-of-experimental-temporalis-muscle-pain-on-jaw-muscle-electromyographic-activity-during-jaw-movements-and-relationships-with-some-psychological-variables
#9
Tantry Maulina, Magda Amhamed, Terry Whittle, John Gal, Rahena Akhter, Greg M Murray
AIMS: To determine if the effects of experimental temporalis muscle pain on jaw muscle activity vary with the jaw task performed, jaw displacement magnitude, participant being studied, and with psychological measures. METHODS: Jaw movement was tracked, and electromyographic (EMG) activity was recorded from the masseter and anterior temporalis and digastric muscles in 14 asymptomatic participants during standardized opening/closing jaw movement, free chewing, and standardized chewing tasks...
December 15, 2017: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/29239978/picu-length-of-stay-factors-associated-with-bed-utilization-and-development-of-a-benchmarking-model
#10
Murray M Pollack, Richard Holubkov, Ron Reeder, J Michael Dean, Kathleen L Meert, Robert A Berg, Christopher J L Newth, John T Berger, Rick E Harrison, Joseph Carcillo, Heidi Dalton, David L Wessel, Tammara L Jenkins, Robert Tamburro
OBJECTIVES: ICU length of stay is an important measure of resource use and economic performance. Our primary aims were to characterize the utilization of PICU beds and to develop a new model for PICU length of stay. DESIGN: Prospective cohort. The main outcomes were factors associated with PICU length of stay and the performance of a regression model for length of stay. SETTING: Eight PICUs. PATIENTS: Randomly selected patients (newborn to 18 yr) from eight PICUs were enrolled from December 4, 2011, to April 7, 2013...
December 12, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29238586/international-prospective-observational-study-of-upper-gastrointestinal-haemorrhage-does-weekend-admission-affect-outcome
#11
Iain A Murray, Harry R Dalton, Adrian J Stanley, Jing H Ngu, Brian Maybin, Mahmoud Eid, Kenneth G Madsen, Rozeta Abazi, Hamad Ashraf, Mohamed Abdelrahim, Rebecca Lissmann, Jenny Herrod, Christopher Jl Khor, Hock S Ong, Doreen Sc Koay, Yung K Chin, Stig B Laursen
Introduction: Out of hours admissions have higher mortality for many conditions but upper gastrointestinal haemorrhage studies have produced variable outcomes. Methods: Prospective study of 12 months consecutive admissions of upper gastrointestinal haemorrhage from four international high volume centres. Admission period (weekdays, weeknights or weekends), demographics, haemodynamic parameters, laboratory results, endoscopy findings, further procedures and 30-day mortality were recorded...
December 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29236770/association-between-preoperative-peripheral-blood-mononuclear-cell-gene-expression-profiles-early-postoperative-organ-function-recovery-potential-and-long-term-survival-in-advanced-heart-failure-patients-undergoing-mechanical-circulatory-support
#12
Galyna Bondar, Ryan Togashi, Martin Cadeiras, Joanna Schaenman, Richard K Cheng, Lindsay Masukawa, Josephine Hai, Tra-Mi Bao, Desai Chu, Eleanor Chang, Maral Bakir, Sophie Kupiec-Weglinski, Victoria Groysberg, Tristan Grogan, Joseph Meltzer, Murray Kwon, Maura Rossetti, David Elashoff, Elaine Reed, Pei Pei Ping, Mario C Deng
BACKGROUND: Multiorgan dysfunction syndrome contributes to adverse outcomes in advanced heart failure (AdHF) patients after mechanical circulatory support (MCS) implantation and is associated with aberrant leukocyte activity. We tested the hypothesis that preoperative peripheral blood mononuclear cell (PBMC) gene expression profiles (GEP) can predict early postoperative improvement or non-improvement in patients undergoing MCS implantation. We believe this information may be useful in developing prognostic biomarkers...
2017: PloS One
https://www.readbyqxmd.com/read/29208447/impact-of-advanced-practice-registered-nurses-on-quality-measures-the-missouri-quality-initiative-experience
#13
Marilyn J Rantz, Lori Popejoy, Amy Vogelsmeier, Colleen Galambos, Greg Alexander, Marcia Flesner, Cathy Murray, Charles Crecelius, Bin Ge, Gregory Petroski
PURPOSE: The purpose of this article is to review the impact of advanced practice registered nurses (APRNs) on the quality measure (QM) scores of the 16 participating nursing homes of the Missouri Quality Initiative (MOQI) intervention. The MOQI was one of 7 program sites in the US, with specific interventions unique to each site tested for the Centers for Medicaid and Medicare Services Innovations Center. While the goals of the MOQI for long-stay nursing home residents did not specifically include improvement of the QM scores, it was anticipated that improvement most likely would occur...
December 2, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29201508/how-localized-is-pathologically-localized-prostate-cancer-the-use-of-secondary-circulating-prostate-cells-as-a-marker-of-minimal-residual-disease-and-their-association-with-patient-outcome
#14
Nigel P Murray, Socrates Aedo, Cynthia Fuentealba, Eduardo Reyes, Omar Jacob
Objective: To determine the prognostic value of secondary circulating prostate cells (CPCs) in men with pT2 prostate cancer treated with radical prostatectomy. Material and methods: Prospective observational study was performed in men with pathologically confined prostate cancer who had been treated with radical prostatectomy. CPCs were obtained by differential gel centrifugation from 8 mL venous blood and identified by standard immunocytochemistry using anti-Prostate Specific Antigen (PSA) monoclonal antibody...
December 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/29198994/dietary-quality-and-markers-of-inflammation-no-association-in-youth-with-type-1-diabetes
#15
Angela D Liese, Xiaonan Ma, Xiaoguang Ma, Murray A Mittleman, Natalie S The, Debra A Standiford, Jean M Lawrence, Catherine Pihoker, Santica M Marcovina, Elizabeth J Mayer-Davis, Robin C Puett
BACKGROUND: Systemic inflammation is a key process underlying cardiovascular disease (CVD) development, and CVD risk is significantly elevated in persons with type 1 diabetes (T1D). Youth with T1D exhibit increased levels of inflammation. Studies in persons without diabetes suggest that dietary quality influences inflammation, yet little is known about dietary influences on inflammation in youth with T1D. METHODS: This study evaluated the association of four distinct dietary quality indices (Dietary Approaches to Stop Hypertension (DASH), Healthy Eating Index 2010 (HEI2010), modified KIDMED and Total Antioxidant Capacity (TAC)) with biomarkers of inflammation (C-reactive protein (CRP), fibrinogen and interleukin-6 (IL-6)) in a sample of 2520 youth with T1D participating in the SEARCH for Diabetes in Youth Study...
November 6, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/29194562/a-risk-score-including-microdeletions-improves-relapse-prediction-for-standard-and-medium-risk-precursor-b-cell-acute-lymphoblastic-leukaemia-in-children
#16
Rosemary Sutton, Nicola C Venn, Tamara Law, Judith M Boer, Toby N Trahair, Anthea Ng, Monique L Den Boer, Anuruddhika Dissanayake, Jodie E Giles, Pauline Dalzell, Chelsea Mayoh, Draga Barbaric, Tamas Revesz, Frank Alvaro, Rob Pieters, Michelle Haber, Murray D Norris, Martin Schrappe, Luciano Dalla Pozza, Glenn M Marshall
To prevent relapse, high risk paediatric acute lymphoblastic leukaemia (ALL) is treated very intensively. However, most patients who eventually relapse have standard or medium risk ALL with low minimal residual disease (MRD) levels. We analysed recurrent microdeletions and other clinical prognostic factors in a cohort of 475 uniformly treated non-high risk precursor B-cell ALL patients with the aim of better predicting relapse and refining risk stratification. Lower relapse-free survival at 7 years (RFS) was associated with IKZF1 intragenic deletions (P < 0·0001); P2RY8-CRLF2 gene fusion (P < 0·0004); Day 33 MRD>5 × 10-5 (P < 0·0001) and High National Cancer Institute (NCI) risk (P < 0·0001)...
November 30, 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/29193603/quality-of-life-in-adolescents-with-hepatitis-c-treated-with-sofosbuvir-and-ribavirin
#17
Zobair M Younossi, Maria Stepanova, Kathleen B Schwarz, Stefan Wirth, Philip Rosenthal, Regino Gonzalez-Peralta, Karen Murray, Linda Henry, Sharon Hunt
Chronic HCV infection has been associated with impairment of health-related quality of life (HRQL) in both adults and pediatric patients. Our aim was to assess the HRQL of HCV-positive children treated with SOF+RBV. The data for this post-hoc analysis was collected in a phase 2 open-label multinational study that evaluated safety and efficacy of sofosbuvir (400mg/day) plus ribavirin (weight-based up to 1400mg/day) for 12 or 24 weeks in adolescents with chronic HCV (GS-US-334-1112). Patients and their parents/guardians completed the PedsQL-4...
November 28, 2017: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/29193291/validity-and-reliability-of-a-portuguese-version-of-the-summated-xerostomia-inventory-5
#18
João Pedro de Almeida Rato Amaral, Duarte Nuno da Silva Marques, William Murray Thomson, Alexandra Rosa Rodrigues Vinagre, António Duarte Sola Pereira da Mata
OBJECTIVES: The aim of this study was to validate and determine the reliability of the Portuguese version of the Summated Xerostomia Inventory. BACKGROUND: Many conditions such as head and neck radiation, autoimmune diseases or polypharmacy are characterised by hyposalivation which can affect oral and systemic quality of life. As such, this condition must be assessed, and the English version of the Xerostomia Inventory has been increasingly used to determine the severity of dry mouth perception...
November 27, 2017: Gerodontology
https://www.readbyqxmd.com/read/29180005/leisure-time-physical-activity-across-adulthood-and-biomarkers-of-cardiovascular-disease-at-age-60-64-a-prospective-cohort-study
#19
Ahmed Elhakeem, Emily T Murray, Rachel Cooper, Diana Kuh, Peter Whincup, Rebecca Hardy
BACKGROUND AND AIMS: This study examined associations between leisure-time physical activity (LTPA) across adulthood (from age 36) and cardiovascular disease (CVD) biomarkers at age 60-64. METHODS: LTPA was reported by study participants from the MRC National Survey of Health and Development at ages 36, 43, 53 and 60-64 (n = 1754) and categorised as inactive, moderately active (1-4/month) or most active (5+/month) at each age. Linear regression was used to examine associations between a cumulative adulthood LTPA score (range = 0-8), and change in LTPA between ages 36 and 60-64 (i...
November 20, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29178946/a-putative-causal-relationship-between-genetically-determined-female-body-shape-and-posttraumatic-stress-disorder
#20
Renato Polimanti, Ananda B Amstadter, Murray B Stein, Lynn M Almli, Dewleen G Baker, Laura J Bierut, Bekh Bradley, Lindsay A Farrer, Eric O Johnson, Anthony King, Henry R Kranzler, Adam X Maihofer, John P Rice, Andrea L Roberts, Nancy L Saccone, Hongyu Zhao, Israel Liberzon, Kerry J Ressler, Caroline M Nievergelt, Karestan C Koenen, Joel Gelernter
BACKGROUND: The nature and underlying mechanisms of the observed increased vulnerability to posttraumatic stress disorder (PTSD) in women are unclear. METHODS: We investigated the genetic overlap of PTSD with anthropometric traits and reproductive behaviors and functions in women. The analysis was conducted using female-specific summary statistics from large genome-wide association studies (GWAS) and a cohort of 3577 European American women (966 PTSD cases and 2611 trauma-exposed controls)...
November 27, 2017: Genome Medicine
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