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https://www.readbyqxmd.com/read/27899105/non-invasive-mechanical-ventilation-after-heart-surgery-in-children
#1
Sarah Fernández Lafever, Blanca Toledo, Miguel Leiva, Maite Padrón, Marina Balseiro, Angel Carrillo, Jesús López-Herce
BACKGROUND: The purpose of the study was to analyze the characteristics and evolution of non-invasive mechanical ventilation (NIV) in the postoperative period of heart surgery in children. METHODS: Retrospective observational study including all children requiring NIV after heart surgery in a single center pediatric intensive care unit (PICU) between 2001 and 2012. Demographic characteristics, ventilation parameters and outcomes were registered, comparing the first 6 years of the study with the last 6 years...
November 29, 2016: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/27893388/sparse-representation-based-multiple-frame-video-super-resolution
#2
Qiqin Dai, Seunghwan Yoo, Armin Kappeler, Aggelos K Katsaggelos
In this paper, we propose two multiple-frame superresolution (SR) algorithms based on dictionary learning and motion estimation. First, we adopt the use of video bilevel dictionary learning which has been used for single-frame SR. It is extended to multiple frames by using motion estimation with subpixel accuracy. We propose a batch and a temporally recursive multi-frame SR algorithm, which improve over single frame SR. Finally, we propose a novel dictionary learning algorithm utilizing consecutive video frames, rather than still images or individual video frames, which further improves the performance of the video SR algorithms...
November 22, 2016: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/27835720/a-novel-therapy-for-chronic-sleep-onset-insomnia-a-retrospective-nonrandomized-controlled-study-of-auto-adjusting-dual-level-positive-airway-pressure-technology
#3
Barry Krakow, Victor A Ulibarri, Natalia D McIver, Michael R Nadorff
Objective: Evidence indicates that behavioral or drug therapy may not target underlying pathophysiologic mechanisms for chronic insomnia, possibly due to previously unrecognized high rates (30%-90%) of sleep apnea in chronic insomnia patients. Although treatment studies with positive airway pressure (PAP) demonstrate decreased severity of chronic sleep maintenance insomnia in patients with co-occurring sleep apnea, sleep-onset insomnia has not shown similar results. We hypothesized advanced PAP technology would be associated with decreased sleep-onset insomnia severity in a sample of predominantly psychiatric patients with comorbid sleep apnea...
September 29, 2016: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/27831875/bilevel-model-based-discriminative-dictionary-learning-for-recognition
#4
Pan Zhou, Chao Zhang, Zhouchen Lin
Most supervised dictionary learning methods optimize the combinations of reconstruction error, sparsity prior, and discriminative terms. Thus the learnt dictionaries may not be optimal for recognition tasks. Also, the sparse codes learning models in the training and the testing phases are inconsistent. Besides, without utilizing the intrinsic data structure, many dictionary learning methods only employ the `0 or `1 norm to encode each datum independently, limiting the performance of the learnt dictionaries...
October 31, 2016: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/27825693/use-of-nitroglycerin-by-bolus-prevents-intensive-care-unit-admission-in-patients-with-acute-hypertensive-heart-failure
#5
Suprat Saely Wilson, Gregory M Kwiatkowski, Scott R Millis, John D Purakal, Arushi P Mahajan, Phillip D Levy
OBJECTIVES: The purpose of this study was to compare health care resource utilization among patients who were given intravenous nitroglycerin for acute heart failure (AHF) in the emergency department (ED) by intermittent bolus, continuous infusion, or a combination of both. METHODS: We retrospectively identified 395 patients that received nitroglycerin therapy in the ED for the treatment of AHF over a 5-year period. Patients that received intermittent bolus (n=124) were compared with continuous infusion therapy (n=182) and combination therapy of bolus and infusion (n=89)...
October 18, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27819480/an-enhanced-memetic-algorithm-for-single-objective-bilevel-optimization-problems
#6
Md Monjurul Islam, Hemant Kumar Singh, Tapabrata Ray, Ankur Sinha
Bilevel optimization, as the name reflects, deals with optimization at two interconnected hierarchical levels. The aim is to identify the optimum of an upper level leader problem, subject to the optimality of a lower level follower problem. Several problems from the domain of engineering, logistics, economics and transportation have inherent nested structure which requires them to be modeled as bilevel optimization problems. Increasing size and complexity of such problems has prompted active theoretical and practical interest in the design of efficient algorithms for bilevel optimization...
November 7, 2016: Evolutionary Computation
https://www.readbyqxmd.com/read/27810835/bi-level-and-bi-objective-p-median-type-problems-for-integrative-clustering-application-to-analysis-of-cancer-gene-expression-and-drug-response-data
#7
Anton V Ushakov, Xenia Klimentova, Igor Vasilyev
Recent advances in high-throughput technologies have given rise to collecting large amounts of multidimensional heterogeneous data that provide diverse information on the same biological samples. Integrative analysis of such multisource datasets may reveal new biological insights into complex biological mechanisms and therefore remains an important research field in systems biology. Most of the modern integrative clustering approaches rely on independent analysis of each dataset and consensus clustering, probabilistic or statistical modeling, while flexible distance-based integrative clustering techniques are sparsely covered...
October 27, 2016: IEEE/ACM Transactions on Computational Biology and Bioinformatics
https://www.readbyqxmd.com/read/27720457/positive-airway-pressure-therapy-for-obstructive-sleep-apnea
#8
REVIEW
Pnina Weiss, Meir Kryger
Positive airway pressure (PAP) is considered first-line therapy for moderate to severe obstructive sleep apnea and may also be considered for mild obstructive sleep apnea, particularly if it is symptomatic or there are concomitant cardiovascular disorders. Continuous PAP is most commonly used. Other modes, such as bilevel airway pressure, autotitrating positive airway pressure, average volume assured pressure support, and adaptive support ventilation, play important roles in the management of sleep-related breathing disorders...
December 2016: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/27707439/factors-associated-with-changes-in-invasive-and-noninvasive-positive-airway-pressure-therapy-settings-during-pediatric-polysomnograms
#9
Gyambo Sithey, Li Ming Wen, Patrick Kelly, Mu Li
STUDY OBJECTIVES: Our aim was to identify clinical predictors associated with changes in settings for pediatric invasive and noninvasive positive airway pressure therapy, which could help inform the allocation of limited polysomnogram (PSG) resources. METHODS: A retrospective review was conducted in children who underwent one or more PSGs for technology titration. Children were included if they were using continuous positive airway pressure (CPAP) therapy, bilevel positive airway pressure (BPAP) therapy, or invasive positive pressure ventilation (IPPV) the night of the PSG...
September 29, 2016: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/27591801/objective-adherence-to-positive-airway-pressure-therapy-in-an-australian-paediatric-cohort
#10
Rita Machaalani, Carla A Evans, Karen A Waters
PURPOSE: This study aimed to objectively measure adherence (compliance) and effectiveness of CPAP and BiLevel pressure support in an Australian paediatric population and determine factors associated with adherence outcomes. METHODS: Data was collected as part of routine clinical care from 2011 to 2013. Adherence was recorded by downloads from the PAP device. "Adequate" adherence was defined as ≥4 h/night for 70 % of days used. Effectiveness of therapy was measured by polysomnography (PSG) pre- and post-PAP initiation...
September 3, 2016: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/27555802/clinical-predictors-of-central-sleep-apnea-evoked-by-positive-airway-pressure-titration
#11
Marilyn Moro, Karen Gannon, Kathy Lovell, Margaret Merlino, James Mojica, Matt T Bianchi
PURPOSE: Treatment-emergent central sleep apnea (TECSA), also called complex apnea, occurs in 5%-15% of sleep apnea patients during positive airway pressure (PAP) therapy, but the clinical predictors are not well understood. The goal of this study was to explore possible predictors in a clinical sleep laboratory cohort, which may highlight those at risk during clinical management. METHODS: We retrospectively analyzed 728 patients who underwent PAP titration (n=422 split-night; n=306 two-night)...
2016: Nature and Science of Sleep
https://www.readbyqxmd.com/read/27552766/a-neurodynamic-optimization-approach-to-bilevel-quadratic-programming
#12
Sitian Qin, Xinyi Le, Jun Wang
This paper presents a neurodynamic optimization approach to bilevel quadratic programming (BQP). Based on the Karush-Kuhn-Tucker (KKT) theorem, the BQP problem is reduced to a one-level mathematical program subject to complementarity constraints (MPCC). It is proved that the global solution of the MPCC is the minimal one of the optimal solutions to multiple convex optimization subproblems. A recurrent neural network is developed for solving these convex optimization subproblems. From any initial state, the state of the proposed neural network is convergent to an equilibrium point of the neural network, which is just the optimal solution of the convex optimization subproblem...
August 19, 2016: IEEE Transactions on Neural Networks and Learning Systems
https://www.readbyqxmd.com/read/27532363/heated-humidified-high-flow-nasal-cannula-vs-nasal-continuous-positive-airway-pressure-for-respiratory-distress-syndrome-of-prematurity-a-randomized-clinical-noninferiority-trial
#13
Anna Lavizzari, Mariarosa Colnaghi, Francesca Ciuffini, Chiara Veneroni, Stefano Musumeci, Ivan Cortinovis, Fabio Mosca
Importance: Heated, humidified high-flow nasal cannula (HHHFNC) has gained increasing popularity as respiratory support for newborn infants thanks to ease of use and improved patient comfort. However, its role as primary therapy for respiratory distress syndrome (RDS) of prematurity needs to be further elucidated by large, randomized clinical trials. Objective: To determine whether HHHFNC provides respiratory support noninferior to nasal continuous positive airway pressure (nCPAP) or bilevel nCPAP (BiPAP) as a primary approach to RDS in infants older than 28 weeks' gestational age (GA)...
August 8, 2016: JAMA Pediatrics
https://www.readbyqxmd.com/read/27427880/a-more-rapid-rapid-response
#14
Justin Robison, Nicholas B Slamon
OBJECTIVES: Critical care physicians' standard for arrival to a rapid response team activation is 10 minutes or less at this institution. This study proposes that a FaceTime (Apple, Cupertino, CA) video call between the staff at the bedside and the critical care physician will allow the implementation of potentially life-saving therapies earlier than the current average response (4.5 min). DESIGN: Prospective cohort study. SETTING: Freestanding, tertiary-care children's hospital...
September 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27378721/logistic-regression-analysis-of-pierre-robin-sequence-patients-requiring-surgical-intervention
#15
Steven Goudy, Pawina Jiramongolchai, Sivakumar Chinnadurai
OBJECTIVES/HYPOTHESIS: Determine predictive patient characteristics that guide the decision to proceed with surgical management of tongue-based airway obstruction (TBAO) in Pierre Robin sequence (PRS) patients. STUDY DESIGN: Retrospective review of PRS patients between 2005 and 2014 requiring observation in the neonatal intensive care unit (NICU). METHODS: Patient charts were reviewed for prenatal diagnoses, clinical course, and need for surgical intervention (tracheotomy or mandibular distraction osteogenesis), and the nonsurgical and surgical group were compared with a logistic regression model...
July 5, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27366506/comparison-and-evaluation-of-the-effects-of-administration-of-postoperative-non-invasive-mechanical-ventilation-methods-cpap-and-bipap-on-respiratory-mechanics-and-gas-exchange-in-patients-undergoing-abdominal-surgery
#16
Hatice Yağlıoğlu, Güniz Meyancı Köksal, Emre Erbabacan, Birsel Ekici
OBJECTIVE: The aim of our study is to investigate the effect of two different methods of continuous positive airway pressure (CPAP) and bilevel positive airway pressure (BIPAP) and oxygen support under spontaneous ventilation on respiration mechanics, gas exchange, dry mouth and face mask lesion during an early postoperative period in patients undergoing upper abdominal surgery. METHODS: Eighty patients undergoing elective abdominal surgery with laparotomy, between the age of 25 and 75 years and American Society of Anesthesiologists Physical Status score (ASA) II-III with chronic obstructive pulmonary disease (COPD) diagnosis were included to the study...
August 2015: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/27324412/prediction-of-cancer-drug-sensitivity-using-high-dimensional-omic-features
#17
Ting-Huei Chen, Wei Sun
SummaryA large number of cancer drugs have been developed to target particular genes/pathways that are crucial for cancer growth. Drugs that share a molecular target may also have some common predictive omic features, e.g., somatic mutations or gene expression. Therefore, it is desirable to analyze these drugs as a group to identify the associated omic features, which may provide biological insights into the underlying drug response. Furthermore, these omic features may be robust predictors for any drug sharing the same target...
June 20, 2016: Biostatistics
https://www.readbyqxmd.com/read/27310926/in-vitro-comparison-of-a-vibrating-mesh-nebulizer-operating-in-inspiratory-synchronized-and-continuous-nebulization-modes-during-noninvasive-ventilation
#18
Jean-Bernard Michotte, Enrico Staderini, Deborah Le Pennec, Jonathan Dugernier, Rares Rusu, Jean Roeseler, Laurent Vecellio, Giuseppe Liistro, Grégory Reychler
UNLABELLED: Backround: Coupling nebulization with noninvasive ventilation (NIV) has been shown to be effective in patients with respiratory diseases. However, a breath-synchronized nebulization option that could potentially improve drug delivery by limiting drug loss during exhalation is currently not available on bilevel ventilators. The aim of this in vitro study was to compare aerosol delivery of amikacin with a vibrating mesh nebulizer coupled to a single-limb circuit bilevel ventilator, using conventional continuous (Conti-Neb) and experimental inspiratory synchronized (Inspi-Neb) nebulization modes...
August 2016: Journal of Aerosol Medicine and Pulmonary Drug Delivery
https://www.readbyqxmd.com/read/27307723/nasal-highflow-improves-ventilation-in-patients-with-copd
#19
Jens Bräunlich, Marcus Köhler, Hubert Wirtz
BACKGROUND: Nasal highflow (NHF) provides a warmed and humidified air stream up to 60 L/min. Recent data demonstrated a positive effect in patients with acute hypoxemic respiratory failure, especially when caused by pneumonia. Preliminary data show a decrease in hypercapnia in patients with COPD. Therefore, NHF should be evaluated as a new ventilatory support device. This study was conducted to assess the impact of different flow rates on ventilatory parameters in patients with COPD. MATERIALS AND METHODS: This interventional clinical study was performed with patients suffering from severe COPD...
2016: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/27266279/approach-of-pulmonologists-in-turkey-to-noninvasive-mechanical-ventilation-use-at-home-for-chronic-respiratory-failure
#20
Aylin Özsancak Uğurlu, Huriye Berk Takır, Begüm Ergan, Erdal İn, Ezgi Özyilmaz, Özlem Ertan Edipoğlu, Eylem Acartürk, Ege Güleç Balbay, Aslı Görek Dilektaşlı, Tülay Kıvanç, Pervin Korkmaz Ekren, Sevinç Sarınç Ulaşlı, Ilgaz Doğrul, Elif Yılmazel Uçar, Şehnaz Olgun, Özkan Devran, Recai Ergun, Zuhal Karakurt
INTRODUCTION: To define approach of pulmonologists in Turkey to noninvasive mechanical ventilation (NIV) use for chronic respiratory failure (CRF), the most currently applied technique for home mechanical ventilation. PATIENTS AND METHODS: A 38-question survey, developed and tested by the authors, was distributed throughout Turkey to 2205 pulmonologists by e-mail. RESULT: Twenty-seven percent of the pulmonologists responded (n=596). Domiciliary NIV was reported to be prescribed by 340 physicians [57...
December 0: Tüberküloz Ve Toraks
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