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https://www.readbyqxmd.com/read/29471590/consumer-use-and-response-to-online-third-party-raw-dna-interpretation-services
#1
Catharine Wang, Tiernan J Cahill, Andrew Parlato, Blake Wertz, Qiankun Zhong, Tricia Norkunas Cunningham, James J Cummings
BACKGROUND: With the availability of raw DNA generated from direct-to-consumer (DTC) testing companies, there has been a proliferation of third-party online services that are available to interpret the raw data for both genealogy and/or health purposes. This study examines the current landscape and downstream clinical implications of consumer use of third-party services. METHODS: Study participants were recruited online from social media platforms. A total of 321 survey respondents reported using third-party services for raw DNA interpretation...
January 2018: Molecular Genetics & Genomic Medicine
https://www.readbyqxmd.com/read/29471260/stress-underestimation-and-mental-health-literacy-of-depression-in-japanese-workers-a-cross-sectional-study
#2
Nanako Nakamura-Taira, Shuhei Izawa, Kosuke Chris Yamada
Appropriately estimating stress levels in daily life is important for motivating people to undertake stress-management behaviors or seek out information on stress management and mental health. People who exhibit high stress underestimation might not be interested in information on mental health, and would therefore have less knowledge of it. We investigated the association between stress underestimation tendency and mental health literacy of depression (i.e., knowledge of the recognition, prognosis, and usefulness of resources of depression) in Japanese workers...
January 2, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29471158/road-traffic-injuries-cross-sectional-cluster-randomized-countrywide-population-data-from-4-low-income-countries
#3
Syed Nabeel Zafar, Joseph K Canner, Neeraja Nagarajan, Adam L Kushner
INTRODUCTION: Road traffic injuries (RTI) are a leading cause of morbidity and mortality around the world. The burden is highest in low and middle-income countries (LMICs) and is increasing. We aimed to describe the epidemiology of RTIs in 4 low-income countries using nationally representative survey data. METHODS: The Surgeons Overseas Assessment of Surgical Needs (SOSAS) survey tool was administered in four countries: Sierra Leone, Rwanda, Nepal and Uganda. We performed nationally representative cross-sectional, cluster randomized surveys in each country...
February 19, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29469693/dermatology-on-reddit-elucidating-trends-in-dermatologic-communications-on-the-world-wide-web
#4
Talayesa Buntinx-Krieg, Joseph Caravaglio, Renee Domozych, Robert P Dellavalle
Platforms of social media, including the website Reddit, have become increasingly popular sites for users to communicate medical information. A study investigating dermatology content on Reddit has not been performed in the current literature. The purpose of this study is to enumerate the dermatology subreddits, quantify subscribers, and characterize posts to estimate the presence of dermatology-related content on Reddit. A Reddit search of the fourteen most common skin diseases globally was performed. Additionally, the terms "dermatology", and "skin" were searched in order to identify more subreddits relevant to the field...
July 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/29469551/don%C3%A2-t-try-this-at-home-the-fda%C3%A2-s-restrictive-regulation-of-home-testing-devices
#5
Shelby Baird
Over the past forty years, the Food and Drug Administration (FDA) has successfully restricted consumers' access to home-testing applications based on the notion that it should protect individuals from their own reactions to test results. In the 1970s, the FDA briefly denied women access to home pregnancy tests that were identical to those used in laboratories. In the late 1980s and early 1990s, it relied on concerns about consumer responses to HIV status results to justify a categorical ban on applications for HIV home-testing technology...
November 2017: Duke Law Journal
https://www.readbyqxmd.com/read/29468543/detection-of-retinoblastoma-protein-phosphorylation-by-immunoblot-analysis
#6
Pedro G Santiago-Cardona, Jaileene Pérez-Morales, Jonathan González-Flores
The retinoblastoma tumor suppressor protein (pRb) is a preeminent tumor suppressor that acts as a cell cycle repressor, specifically as an inhibitor of the G1-S transition of the cell cycle . pRb is a phosphoprotein whose function is repressed by extensive phosphorylation in several key residues, and therefore, pRb's phosphorylation status has become a surrogate for pRb activity. In particular, hyperphosphorylation of pRb has been associated with pathological states such as cancer, and therefore, assessing pRb's phosphorylation status is increasingly gaining diagnostic and prognostic value, may be used to inform therapeutic decisions, and is also an important tool for the cancer biologists seeking an understanding of the molecular etiology of cancer...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29467257/product-diffusion-through-on-demand-information-seeking-behaviour
#7
Christoph Riedl, Johannes Bjelland, Geoffrey Canright, Asif Iqbal, Kenth Engø-Monsen, Taimur Qureshi, Pål Roe Sundsøy, David Lazer
Most models of product adoption predict S-shaped adoption curves. Here we report results from two country-scale experiments in which we find linear adoption curves. We show evidence that the observed linear pattern is the result of active information-seeking behaviour: individuals actively pulling information from several central sources facilitated by modern Internet searches. Thus, a constant baseline rate of interest sustains product diffusion, resulting in a linear diffusion process instead of the S-shaped curve of adoption predicted by many diffusion models...
February 2018: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/29467067/a-brief-review-of-caprylidene-axona-and-coconut-oil-as-alternative-fuels-in-the-fight-against-alzheimer-s-disease
#8
Monica Chintapenta, Justin Spence, Hyanggi Irene Kwon, Amie Taggart Blaszczyk
Type 3 diabetes mellitus has been coined to describe an alternative pathologic pathway of Alzheimer's disease (AD). The insulin resistance and impaired insulin signaling seen on positron-emission tomography scans in the brain of those affected by AD support this disease hypothesis. Two products-the medical food caprylidene (Axona) and coconut oil-seek to target the underlying pathology of type 3 diabetes mellitus by providing an alternative fuel source in the brain. Rather than improving glucose utilization, these two products seek to supply ketone bodies in sufficient quantities to pass through the blood-brain barrier and provide an alternative energy source to glucose...
December 1, 2017: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
https://www.readbyqxmd.com/read/29467051/primary-care-medical-practices-are-community-health-care-providers-ready-for-disasters
#9
Rachel M Peters, Thomas J Hipper, Esther D Chernak
OBJECTIVE: This study seeks to determine the capacity of community primary care practices to meet the needs of patients during public health emergencies and to identify the barriers and resources necessary to participate in a coordinated response with public safety agencies. METHODS: The self-administered web-based survey was distributed in January 2014 via e-mail to primary care providers in Pennsylvania using the listservs of several professional societies. RESULTS: A total of 179 primary care providers participated in the survey...
February 22, 2018: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/29467040/knowledge-sharing-between-general-and-pediatric-emergency-departments-connections-barriers-and-opportunities
#10
Leah K Crockett, Carly Leggett, Janet A Curran, Lisa Knisley, Gwenyth Brockman, Shannon D Scott, Lisa Hartling, Mona Jabbour, Terry P Klassen
CLINICIAN'S CAPSULE What is known about this topic? Evidence-based pediatric emergency care is variably applied across general and pediatric emergency departments. What did this study ask? What are the information-seeking patterns of pediatric emergency medicine network members? What did this study find? There remains a need to share successful methods of local dissemination and implementation across the network, and to leverage local professional champions such as clinical nurse liaisons. Why does this study matter to clinicians? Tailoring knowledge mobilization efforts to end-user priorities is essential to ensure impact and spread of outreach efforts...
February 22, 2018: CJEM
https://www.readbyqxmd.com/read/29466062/management-of-diabetes-during-air-travel-a-systematic-literature-review-of-current-recommendations-and-their-supporting-evidence
#11
James Pavela, Rahul Suresh, Rebecca S Blue, Charles H Mathers, L Maria Belalcazar
OBJECTIVE: Individuals with diabetes are increasingly seeking pretravel advice, but updated professional recommendations remain scant. We performed a systematic review on diabetes management during air travel to summarize current recommendations, assess supporting evidence, and identify areas of future research. METHODS: A systematic review of the English literature on diabetes management during air travel was undertaken utilizing PubMed and MEDLINE. Publications regarding general travel advice; adjustment of insulin and noninsulin therapies; and the use of insulin pumps, glucometers and subcutaneous glucose sensors at altitude were included...
February 2018: Endocrine Practice
https://www.readbyqxmd.com/read/29465638/out-of-the-closet-into-the-clinic-opportunities-for-expanding-msm-competent-services-in-china
#12
Julia Watson, Weiming Tang, Stephen Pan, Dan Wu, Peipei Zhao, Bolin Cao, Chuncheng Liu, Cedric Bien, Wenting Huang, Zhenzhou Luo, Joseph D Tucker
BACKGROUND: Despite the high HIV burden among men who have sex with men (MSM), there is little research on health services provided to MSM in China and other low- and middle-income countries. Discrimination and inadequate services may discourage MSM from seeking healthcare services. This study examined essential services provided to MSM and healthcare discrimination among MSM in China. METHODS: A nationwide cross-sectional online survey was conducted among MSM who saw a physician in the last 24 months in China...
February 13, 2018: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29464132/crowd-sourced-ontology-for-photoleukocoria-identifying-common-internet-search-terms-for-a-potentially-important-pediatric-ophthalmic-sign
#13
Sandra E Staffieri, Lisa S Kearns, Paul G Sanfilippo, Jamie E Craig, David A Mackey, Alex W Hewitt
Purpose: Leukocoria is the most common presenting sign for pediatric eye disease including retinoblastoma and cataract, with worse outcomes if diagnosis is delayed. We investigated whether individuals could identify leukocoria in photographs (photoleukocoria) and examined their subsequent Internet search behavior. Methods: Using a web-based questionnaire, in this cross-sectional study we invited adults aged over 18 years to view two photographs of a child with photoleukocoria, and then search the Internet to determine a possible diagnosis and action plan...
February 2018: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/29462305/health-insurance-and-care-seeking-behaviours-of-female-migrants-in-accra-ghana
#14
Samantha R Lattof
People working in Ghana's informal sector have low rates of enrolment in the publicly funded National Health Insurance Scheme. Informal sector workers, including migrant girls and women from northern Ghana working as head porters (kayayei), report challenges obtaining insurance and seeking formal health care. This article analyses how health insurance status affects kayayei migrants' care-seeking behaviours. This mixed-methods study involved surveying 625 migrants using respondent-driven sampling and conducting in-depth interviews with a sub-sample of 48 migrants...
February 15, 2018: Health Policy and Planning
https://www.readbyqxmd.com/read/29461285/gauging-the-effects-of-self-efficacy-social-support-and-coping-style-on-self-management-behaviors-in-chinese-cancer-survivors
#15
Zhaohui Geng, Yolanda Ogbolu, Jichuan Wang, Pamela S Hinds, Huijuan Qian, Changrong Yuan
BACKGROUND: Better self-management control in cancer survivors would benefit their functional status, quality of life, and health service utilization. Factors such as self-efficacy, social support, and coping style are important predictors of self-management behaviors of cancer survivors; however, the impact of these factors on self-management behaviors has not yet been empirically tested in Chinese cancer survivors. OBJECTIVES: The aim of this study was to examine how self-efficacy, social support, and coping style affect specific self-management behaviors...
February 14, 2018: Cancer Nursing
https://www.readbyqxmd.com/read/29461138/enablers-and-barriers-to-the-development-of-interprofessional-collaboration-between-physicians-and-osteopaths-a-mixed-methods-study
#16
Chantal Morin, Johanne Desrosiers, Isabelle Gaboury
Osteopathy is a complementary and alternative medicine (CAM) that is growing in popularity. Increasing numbers of parents are seeking pediatric osteopathic care in addition to conventional medical care. Information about the development of interprofessional collaboration (IPC) between these practitioners is scarce. This explanatory sequential mixed methods study aimed to explore enablers of and barriers to the development of IPC between physicians and osteopaths involved with pediatric patients in primary care in Quebec, Canada...
February 20, 2018: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/29461112/-self-takes-it-all-in-mental-illness-examining-the-dynamic-role-of-health-consciousness-negative-emotions-and-efficacy-in-information-seeking
#17
Jiyoung Lee
Mental illness such as depression, stress, and anxiety disorder is prevalent in our everyday lives. Yet, little is known about how health-related variables operate in the mental illness context. Centering on health consciousness, this study systematically examines how health consciousness affects information seeking and whether negative emotions and efficacy intervene in the relationship in mental illness. The results of the survey (N = 614) suggest that health consciousness relates to fear, anxiety, self-efficacy, and response efficacy but does not relate to information seeking...
February 20, 2018: Health Communication
https://www.readbyqxmd.com/read/29460794/definitions-of-hunger-and-fullness-among-youth-enrolled-in-a-pediatric-weight-management-program
#18
Heather Bernstein, Melissa Santos
The development and maintenance of obesity is multifactorial and involves the interplay of environmental, cultural, social, and biological influences. The purpose of the current paper was to describe hunger and fullness in a sample of pediatric patients seeking treatment for obesity. The goals of this study were to gain information about how youth with obesity describe their experience of being hungry and full and to explore common themes within these descriptions. Twenty-five patients entering a Stage 3 pediatric obesity program responded to the open-ended questions: "how do you know when you are hungry" and "how do you know when you are full?" The results found that the majority of youth used physical cues as a way to identify hunger and fullness cues...
February 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29460769/graphic-pathographies-and-the-ethical-practice-of-person-centered-medicine
#19
Kimberly R Myers, Michael D F Goldenberg
Graphic medicine is a swiftly growing movement that explores, theoretically and practically, the use of comics in medical education and patient care. At the heart of graphic medicine are graphic pathographies, stories of illness conveyed in comic form. These stories are helpful tools for health care professionals who seek new insight into the personal, lived experience of illness and for patients who want to learn more about their disease from others who have actually experienced it. Featuring excerpts from five graphic pathographies, this essay illustrates how the medium can be used to educate patients and enhance empathy in health care professionals, particularly with regard to informed consent and end-of-life issues...
February 1, 2018: AMA Journal of Ethics
https://www.readbyqxmd.com/read/29460275/community-screening-for-visual-impairment-in-older-people
#20
REVIEW
Emily L Clarke, Jennifer R Evans, Liam Smeeth
BACKGROUND: Visual problems in older people are common and frequently under-reported. The effects of poor vision in older people are wide reaching and include falls, confusion and reduced quality of life. Much of the visual impairment in older ages can be treated (e.g. cataract surgery, correction of refractive error). Vision screening may therefore reduce the number of older people living with sight loss. OBJECTIVES: The objective of this review was to assess the effects on vision of community vision screening of older people for visual impairment...
February 20, 2018: Cochrane Database of Systematic Reviews
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