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https://www.readbyqxmd.com/read/29770166/free-radical-damage-in-ischemia-reperfusion-injury-an-obstacle-in-acute-ischemic-stroke-after-revascularization-therapy
#1
REVIEW
Ming-Shuo Sun, Hang Jin, Xin Sun, Shuo Huang, Fu-Liang Zhang, Zhen-Ni Guo, Yi Yang
Acute ischemic stroke is a common cause of morbidity and mortality worldwide. Thrombolysis with recombinant tissue plasminogen activator and endovascular thrombectomy are the main revascularization therapies for acute ischemic stroke. However, ischemia-reperfusion injury after revascularization therapy can result in worsening outcomes. Among all possible pathological mechanisms of ischemia-reperfusion injury, free radical damage (mainly oxidative/nitrosative stress injury) has been found to play a key role in the process...
2018: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29765396/acute-in-stent-thrombosis-after-carotid-angioplasty-and-stenting-a-case-report-and-literature-review
#2
Wei Hu, Li Wang, GuoPing Wang
Background: Based on the results of a recent randomized controlled trial, carotid artery stenting (CAS) was regarded as a relatively safe, less invasive treatment of internal carotid artery stenosis. However, cerebral thromboembolic events are the most common complications of CAS. Especially acute stent thrombosis following CAS will be fatal without prompt diagnosis and revascularization. Case Report: We report a case of acute stent thrombosis in whom carotid revascularization was performed successfully via arterial thrombolysis and balloon postdilation...
April 2018: Interventional Neurology
https://www.readbyqxmd.com/read/29762775/combination-superficial-temporal-artery-middle-cerebral-artery-bypass-and-m2-m2-reanastomosis-with-trapping-of-a-stented-distal-middle-cerebral-artery-aneurysm-3-dimensional-operative-video
#3
Jan-Karl Burkhardt, Sonia Yousef, Halima Tabani, Arnau Benet, Roberto Rodriguez Rubio, Michael T Lawton
Distal middle cerebral artery (MCA) aneurysms often have non-saccular morphology and cannot be clipped, requiring revascularization and trapping instead. Combination bypasses are needed when 2 arteries exit the aneurysm, and extracranial-intracranial and intracranial-intracranial bypasses can be used. This video demonstrates a combination bypass used to treat a previously stented distal MCA aneurysm with both a superficial temporal artery (STA)-to-MCA bypass and an M2-to-M2 reanastomosis. This 56-yr-old man presented with distal left-sided MCA aneurysm 2 years earlier and attempted stent-assisted coiling was aborted after the aneurysm was perforated with stenting alone...
May 12, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29747322/-safety-and-efficacy-of-rotational-atherectomy-in-the-interventional-treatment-of-coronary-chronic-total-occlusion-lesions
#4
J Y Ma, J J Guo, L Hou, F Zhang, K Yao, D Huang, H Lu, Y X Dai, C G Li, S F Chang, Q Qin, L Ge, J Y Qian, J B Ge
Objective: To investigate the safety and efficacy of rotational atherectomy in the interventional treatment of coronary chronic total occlusion lesions. Methods: In this retrospective study,a total of 31 consecutive patients with coronary chronic total occlusion(CTO) lesions underwent rotational atherectomy in our hospital from February 2004 to December 2016 were enrolled,and the clinical features were analyzed. Coronary atherectomy was performed if balloon failed to cross the CTO lesions or balloon could not be fully dilated in the CTO lesions after wire crossing...
April 24, 2018: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29743907/circulating-mirna-levels-differ-with-respect-to-carotid-plaque-characteristics-and-symptom-occurrence-in-patients-with-carotid-artery-stenosis-and-provide-information-on-future-cardiovascular-events
#5
Rafal Badacz, Tadeusz Przewłocki, Jacek Gacoń, Ewa Stępień, Francisco J Enguita, Izabela Karch, Krzysztof Żmudka, Anna Kabłak-Ziembicka
Introduction: Circulating microRNAs (miRNAs) levels are potentially important biomarkers and therapeutic targets of cerebral ischemic event (CIE) in patients with internal carotid artery stenosis (ICAS). Aim: This prospective study investigated associations between circulating miRNAs and symptomatic and asymptomatic ICAS, carotid plaque morphology and future cardiovascular events. Material and methods: Circulating miRNAs (miR-1-3p, miR-16-5p, miR-34a-5p, miR-124-3p, miR-133a-3p, miR-133b, miR-134-5p, miR-208b-3p, miR-375 and miR-499-5p) were analyzed in 92 consecutive patients with significant ICAS referred for revascularization...
2018: Postępy W Kardiologii Interwencyjnej, Advances in Interventional Cardiology
https://www.readbyqxmd.com/read/29740385/refocusing-neuroprotection-in-cerebral-reperfusion-era-new-challenges-and-strategies
#6
REVIEW
Xiao-Yi Xiong, Liang Liu, Qing-Wu Yang
Pathophysiological processes of stroke have revealed that the damaged brain should be considered as an integral structure to be protected. However, promising neuroprotective drugs have failed when translated to clinical trials. In this review, we evaluated previous studies of neuroprotection and found that unsound patient selection and evaluation methods, single-target treatments, etc., without cerebral revascularization may be major reasons of failed neuroprotective strategies. Fortunately, this may be reversed by recent advances that provide increased revascularization with increased availability of endovascular procedures...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29731274/development-of-moyamoya-disease-after-non-herpetic-acute-limbic-encephalitis-a-case-report
#7
Yasuhiro Takahashi, Takeshi Mikami, Hime Suzuki, Katsuya Komatsu, Daisuke Yamamoto, Shun Shimohama, Kiyohiro Houkin, Shintaro Sugita, Tadashi Hasegawa, Nobuhiro Mikuni
We report a case of moyamoya disease (MMD), which developed after non-herpetic acute limbic encephalitis (NHALE) associated with anti-leucine-rich glioma-inactivated 1 (LGI1) antibody. The patient's mother had a history of MMD. No vascular lesions were identified at the time of the NHALE. Nine years later, the patient visited our hospital due to memory disturbances and repeated transient ischemic attacks affecting the right limb. Diffusion-weighted magnetic resonance imaging revealed scattered areas of signal hyperintensity, and the patient was ultimately diagnosed with MMD based on angiography...
May 3, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29729474/the-in-situ-side-to-side-bypass-technique-a-comprehensive-review-of-the-technical-characteristics-current-anastomosis-approaches-and-surgical-experience
#8
REVIEW
Long Wang, Li Cai, Hai Qian, Michael T Lawton, Xiang'en Shi
OBJECTIVE: In situ side-to-side (STS) revascularization is an intracranial-intracranial (IC-IC) bypass technique that is increasingly used to treat complex aneurysms and cerebral ischemia. This sophisticated technique involves connecting two proximal parallel vessels to create an artificial conduit for blood flow. This study aims to provide a detailed description of the configuration of the STS bypass technique and extensive information regarding its technical characteristics, current anastomosis approaches and surgical significance...
May 2, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29729468/the-angiography-of-cervical-carotid-plaque-rupture-due-to-percutaneus-transluminal-balloon-arterioplasty
#9
Tomoya Omae, Naomoto Senbokuya, Toshiharu Yanagisawa
The authors describe the rare imaging of plaque rupture at cervical internal carotid artery stenosis after balloon-arterioplasty. The patient was 82 year-old male who was complained of lt. hemiparesis. Magnetic Resonance imaging-diffusion weight imaging revealed multiple high signal intensity at rt. cerebral hemisphere. Magnetic Resonance angiography showed severe stenosis at cervical internal carotid artery. We considered high risk of hyperperfusion syndrome after revascularization. We planned staged angioplasty...
May 2, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29721400/a-direct-aspiration-first-pass-technique-for-mechanical-thrombectomy-in-the-setting-of-a-suspected-cerebral-aneurysm
#10
Ali S Haider, Suraj Sulhan, Dean Leonard, Haris Rana, Umair Khan, Tijani Osumah, Steven Vayalumkal, Richa Thakur, Kennith F Layton
There is little guidance in the literature on which thrombectomy technique is preferred in patients with acute ischemic stroke and concomitant aneurysms. Here, we present the case of a 58-year-old female with an acute ischemic stroke requiring emergent thrombectomy that was complicated by the presence of multiple, nonruptured intracranial aneurysms. Imaging confirmed an occlusion of the right middle cerebral artery and multiple nonruptured intracranial aneurysms. The patient was administered intravenous recombinant tissue plasminogen activator and the thrombus was aspirated via a direct aspiration first pass technique (ADAPT)...
March 1, 2018: Curēus
https://www.readbyqxmd.com/read/29714677/monitoring-cerebral-perfusion-changes-after-revascularization-in-patients-with-moyamoya-disease-by-using-arterial-spin-labeling-mr-imaging
#11
Seunghyun Lee, Tae Jin Yun, Roh-Eul Yoo, Byung-Woo Yoon, Koung Mi Kang, Seung Hong Choi, Ji-Hoon Kim, Jeong Eun Kim, Chul-Ho Sohn, Moon Hee Han
Purpose To determine whether arterial spin-labeling (ASL) magnetic resonance (MR) imaging could be used to identify changes in cerebral blood flow (CBF), collateral blood flow, and anastomosis site patency after revascularization in patients with moyamoya disease. Materials and Methods This retrospective study was conducted in 145 patients with moyamoya disease who underwent middle cerebral artery (MCA)-superficial temporal artery anastomosis. Preoperative, early postoperative, and late postoperative ASL and digital subtraction angiography images were analyzed...
May 1, 2018: Radiology
https://www.readbyqxmd.com/read/29688196/-ultrasonographic-control-of-cerebral-blood-flow-in-patients-with-stenosis-of-brachiocephalic-arteries-before-and-after-carotid-endarterectomy
#12
I L Bukhovets, A S Maksimova, M P Plotnikov, B N Kozlov, I N Vorozhtsova, V Iu Usov
The authors studied the parameters of arterial and venous blood flow in patients presenting with haemodynamically significant atherosclerosis of the carotid arteries before and after carotid endarterectomy, as well as while carrying out functional tests. Comparing the indices of arterial blood flow in the Study Group consisting of 52 patients and the Control Group comprising 15 apparently healthy volunteers at rest prior to the operation revealed statistically significant differences of volumetric parameters of blood flow in the internal carotid artery...
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/29682422/comparison-of-clinical-outcomes-after-drug-eluting-balloon-and-drug-eluting-stent-use-for-in-stent-restenosis-related-acute-myocardial-infarction-a-retrospective-study
#13
Chih-Yuan Fang, Hsiu-Yu Fang, Chien-Jen Chen, Cheng-Hsu Yang, Chiung-Jen Wu, Wei-Chieh Lee
Background: Good results of drug-eluting balloon (DEB) use are achieved in in-stent restenosis (ISR) lesions, small vessel disease, long lesions, and bifurcations. However, few reports exist about DEB use in acute myocardial infarction (AMI) with ISR. This study's aim was to evaluate the efficacy of DEB for AMI with ISR. Methods: Between November 2011 and December 2015, 117 consecutive patients experienced AMI including ST-segment elevation MI, and non-ST-segment elevation MI due to ISR, and received percutaneous coronary intervention (PCI)...
2018: PeerJ
https://www.readbyqxmd.com/read/29682138/successful-retrograde-recanalization-of-acute-right-dominant-vertebral-artery-occlusion-through-the-left-posterior-communicating-artery-in-a-patient-with-acute-vertebrobasilar-ischemic-stroke
#14
Anton A Khilchuk, Maksim V Agarkov, Sergey V Vlasenko, Sergey G Scherbak, Andrey M Sarana, Svetlana V Lebedeva
Advanced endovascular technology and techniques allow interventional radiologists to utilize novel ways of basilar artery recanalization in the setting of acute ischemic stroke, especially when routine approaches are not eligible. Several authors described nonstandard revascularization techniques in acute ischemic strokes due to basilar and middle cerebral arteries occlusions with full technical and clinical success. In this report, we present retrograde right vertebral artery recanalization using left posterior communicating artery for subsequent anterograde balloon angioplasty and stenting of a right vertebral artery ostium followed by full vertebrobasilar blood flow restoration...
April 2018: Radiology Case Reports
https://www.readbyqxmd.com/read/29681886/importance-of-collateralization-in-patients-with-large-artery-intracranial-occlusive-disease-long-term-longitudinal-assessment-of-cerebral-hemodynamic-function
#15
Larissa McKetton, Lakshmikumar Venkatraghavan, Julien Poublanc, Olivia Sobczyk, Adrian P Crawley, Casey Rosen, Frank L Silver, James Duffin, Joseph A Fisher, David J Mikulis
Patients with large artery intracranial occlusive disease (LAICOD) are at risk for both acute ischemia and chronic hypoperfusion. Collateral circulation plays an important role in prognosis, and imaging plays an essential role in diagnosis, treatment planning, and prognosis of patients with LAICOD. In addition to standard structural imaging, assessment of cerebral hemodynamic function is important to determine the adequacy of collateral supply. Among the currently available methods of assessment of cerebral hemodynamic function, measurement of cerebrovascular reactivity (CVR) using blood oxygen level-dependent (BOLD) MRI and precisely controlled CO2 has shown to be a safe, reliable, reproducible, and clinically useful method for long-term assessment of patients...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29679197/neuropsychological-impacts-of-indirect-revascularization-for-pediatric-moyamoya-disease
#16
WooHyun Kim, Eun-Young Lee, Seong-Eun Park, Eun-Kyung Park, Ju-Seong Kim, Dong-Seok Kim, Kyu-Won Shim
PURPOSE: Moyamoya disease (MMD) commonly leads to neurocognitive impairment. This study was carried out to show that temporal encephaloduroarteriosynangiosis (EDAS) has a positive neuropsychological impact on pediatric MMD patients. METHODS: Fifty-five participants diagnosed with MMD from 2008 to 2014 were included in this retrospective study. The mean age at the preoperative evaluation was 9.5 years and the mean age at postoperative evaluation was 10.4. The average interval of initial and follow-up test was 10 months...
April 20, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29665290/timely-visualization-of-the-collaterals-formed-during-acute-ischemic-stroke-with-fe-3-o-4-nanoparticle-based-mr-imaging-probe
#17
Ting Wang, Yi Hou, Bo Bu, Wenxin Wang, Tiancong Ma, Chunyan Liu, Lan Lin, Lin Ma, Xin Lou, Mingyuan Gao
Ischemic stroke is one of the major leading causes for long-term disability and mortality. Collateral vessels provide an alternative pathway to protect the brain against ischemic injury after arterial occlusion. Aiming at visualizing the collaterals occurring during acute ischemic stroke, an integrin αv β3 -specific Fe3 O4 -Arg-Gly-Asp (RGD) nanoprobe is prepared for magnetic resonance imaging (MRI) of the collaterals. Rat models are constructed by occluding the middle cerebral artery for imaging studies of cerebral ischemia and ischemia-reperfusion on 7...
April 17, 2018: Small
https://www.readbyqxmd.com/read/29660547/surgical-treatment-of-large-or-giant-fusiform-middle-cerebral-artery-aneurysms-a-case-series
#18
Feng Xu, Bin Xu, Lei Huang, Ji Xiong, Yuxiang Gu, Michael T Lawton
BACKGROUND: Management of large or giant fusiform middle cerebral artery (MCA) aneurysms represents a significant challenge. OBJECTIVE: To describe the author's experience in the treatment of large or giant fusiform MCA aneurysm by using various surgical techniques. METHODS: We retrospectively reviewed a database of aneurysm treated at our division between 2015 and 2017. RESULTS: Overall, 20 patients (11 males, 9 females) were identified with a mean age of 40...
April 13, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29643261/primary-results-of-the-multicenter-arise-ii-study-analysis-of-revascularization-in-ischemic-stroke-with-embotrap
#19
Osama O Zaidat, Hormozd Bozorgchami, Marc Ribó, Jeffrey L Saver, Heinrich P Mattle, René Chapot, Ana Paula Narata, Olivier Francois, Ashutosh P Jadhav, Jonathan A Grossberg, Christian H Riedel, Alejandro Tomasello, Wayne M Clark, Hannes Nordmeyer, Eugene Lin, Raul G Nogueira, Albert J Yoo, Tudor G Jovin, Adnan H Siddiqui, Thierry Bernard, Mairsíl Claffey, Tommy Andersson
BACKGROUND AND PURPOSE: EmboTrap is a novel stent retriever designed to achieve rapid and substantial flow restoration in acute ischemic stroke secondary to large-vessel occlusions. Here, we evaluated EmboTrap's safety and efficacy compared with established stent retrievers. METHODS: ARISE II (Analysis of Revascularization in Ischemic Stroke With EmboTrap) was a single-arm, prospective, multicenter study, comparing the EmboTrap device to a composite performance goal criterion derived using a Bayesian meta-analysis from the pivotal SWIFT (Solitaire device) and TREVO 2 (Trevo device) trials...
April 11, 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29626135/feasibility-of-multiple-burr-hole-with-erythropoietin-in-acute-moyamoya-patients
#20
Ji Man Hong, Seong-Joon Lee, Jin Soo Lee, Mun Hee Choi, Sung Eun Lee, Jin Wook Choi, Yong Cheol Lim
BACKGROUND AND PURPOSE: In patients with acute symptomatic moyamoya (<2 weeks), the feasibility of a combination therapy of multiple burr hole procedure under local anesthesia and intravenous erythropoietin pretreatment was assessed. We also identified the factors associated with transdural revascularization. METHODS: In this prospective single-arm study, perfusion-impaired patients presenting with transient ischemic attack or acute cerebral infarction were assessed...
April 6, 2018: Stroke; a Journal of Cerebral Circulation
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