keyword
MENU ▼
Read by QxMD icon Read
search

unloading

keyword
https://www.readbyqxmd.com/read/28110165/pulling-a-school-trolley-a-good-kinematic-option-for-children
#1
Eva Orantes-Gonzalez, Jose Heredia-Jimenez
This study analyzed the kinematic gait parameters associated with pulling a school trolley with different loads and the effects of the type of packing device user (backpack vs. trolley) and body side (loadedunloaded). Methods Fifty-three elementary subjects walked at a selfselected speed under four experimental conditions: without a trolley and pulling a trolley with 10%, 15% and 20% of the subject́s body weight (BW). Averages and standard deviations of spatiotemporal gait parameters and 3D kinematics of the lower limbs and thorax were obtained for the loaded and unloaded sides of the body...
January 15, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28108661/a-structure-function-analysis-of-the-yeast-elg1-protein-reveals-the-importance-of-pcna-unloading-in-genome-stability-maintenance
#2
Keren Shemesh, Marek Sebesta, Martin Pacesa, Soumitra Sau, Alex Bronstein, Oren Parnas, Batia Liefshitz, Česlovas Venclovas, Lumir Krejci, Martin Kupiec
The sliding clamp, PCNA, plays a central role in DNA replication and repair. In the moving replication fork, PCNA is present at the leading strand and at each of the Okazaki fragments that are formed on the lagging strand. PCNA enhances the processivity of the replicative polymerases and provides a landing platform for other proteins and enzymes. The loading of the clamp onto DNA is performed by the Replication Factor C (RFC) complex, whereas its unloading can be carried out by an RFC-like complex containing Elg1...
January 20, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28107240/an-in-vitro-evaluation-of-fracture-reduction-achieved-by-inflatable-bone-tamps-under-simulated-physiological-load
#3
Michael Gordon, Walter C Peppelman, William Beutler, Damien OʼHalloran, Suresh R Chinthakunta, Brandon Bucklen
STUDY DESIGN: An in vitro biomechanical study. OBJECTIVE: To determine the fracture reduction achieved by a novel inflatable bone tamp under simulated physiological load. SUMMARY OF BACKGROUND DATA: Previous biomechanical studies have showed that kyphoplasty allows near-total restoration of lost vertebral height in unloaded conditions and partial height restoration under simulated physiological loads. Clinically, loss of reduction has been observed after bone tamp deflation, before cement injection...
February 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28103546/quantifying-net-synergy-redundancy-of-spontaneous-variability-regulation-via-predictability-and-transfer-entropy-decomposition-frameworks
#4
Alberto Porta, Vlasta Bari, Beatrice De Maria, Anielle C M Takahashi, Stefano Guzzetti, Riccardo Colombo, Aparecida M Catai, Ferdinando Raimondi, Luca Faes
OBJECTIVE: Indexes assessing the balance between redundancy and synergy were hypothesized to be helpful in characterizing cardiovascular control from spontaneous beat-to-beat variations of heart period (HP), systolic arterial pressure (SAP) and respiration (R). METHODS: Net redundancy/synergy indexes were derived according to predictability and transfer entropy decomposition strategies via a multivariate linear regression approach. Indexes were tested in two protocols inducing modifications of the cardiovascular regulation via baroreflex loading/unloading (i...
January 17, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28102849/berberine-sonodynamic-therapy-induces-autophagy-and-lipid-unloading-in-macrophage
#5
Jiayuan Y Kou, Ying Li, Zhaoyu Y Zhong, Yueqing Q Jiang, Xuesong S Li, Xiaobo B Han, Zhongni N Liu, Ye Tian, Liming M Yang
Impaired autophagy in macrophages accompanies the progression of atherosclerosis and contributes to lipid loading in plaques and ineffective lipid degradation. Therefore, evoking autophagy and its associated cholesterol efflux may provide a therapeutic treatment for atherosclerosis. In the present study, berberine-mediated sonodynamic therapy (BBR-SDT) was used to induce autophagy and cholesterol efflux in THP-1 macrophages and derived foam cells. Following BBR-SDT, autophagy was increased in the macrophages, autophagy resistance in the foam cells was prevented, and cholesterol efflux was induced...
January 19, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/28099194/chronic-resistance-training-does-not-ameliorate-unloading-induced-decrements-in-neuromuscular-function
#6
Michael R Deschenes, Raymond W McCoy, Katherine A Mangis
OBJECTIVE: The aim of this study was to assess the efficacy of long-term resistance training in preventing the detrimental effects of muscle unloading on neuromuscular function. DESIGN: Eleven untrained men and 11 men with extensive backgrounds in resistance training were tested for several parameters of neuromuscular function at various isokinetic contractile velocities before and after 7 days of muscle unloading. Measurements included muscle mass, strength, power, total work, electromyography, and neuromuscular transmission efficiency using superimposed electrical stimulation of maximally contracting muscles...
January 17, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28096431/activation-of-respiratory-muscles-does-not-occur-during-cold-submergence-in-bullfrogs-lithobates-catesbeianus
#7
Joseph M Santin, Lynn K Hartzler
Semiaquatic frogs may not breathe air for several months because they overwinter in ice-covered ponds. In contrast to many vertebrates that experience decreased motor performance after inactivity, respiratory motor function in bullfrogs, Lithobates catesbeianus, remains functional following cold-submergence. Unlike mammalian hibernators with unloaded limb muscles and inactive locomotor systems, respiratory mechanics of frogs counterintuitively allow for ventilatory maneuvers when submerged. Thus we hypothesized that bullfrogs generate respiratory motor patterns during cold-submergence to avoid disuse and preserve motor performance...
January 17, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28095452/influence-of-mechanical-circulatory-support-on-endothelin-receptor-expression-in-human-left-ventricular-myocardium-from-patients-with-dilated-cardiomyopathy-dcm
#8
Florian Gärtner, Getu Abraham, Astrid Kassner, Daniela Baurichter, Hendrik Milting
BACKGROUND: In terminal failing hearts ventricular assist devices (VAD) are implanted as a bridge to transplantation. Endothelin receptor (ETR) antagonists are used for treatment of secondary pulmonary hypertension in VAD patients. However, the cardiac ETR regulation in human heart failure and during VAD support is incompletely understood. METHODS: In paired left ventricular samples of 12 dilated cardiomyopathy patients we investigated the density of endothelin A (ETA) and B (ETB) receptors before VAD implantation and after device removal...
2017: PloS One
https://www.readbyqxmd.com/read/28094912/strong-strain-sensing-performance-of-natural-rubber-nanocomposites
#9
Tamil Selvan Natarajan, Eshwaran Subramani Bhagavatheswaran, Klaus Werner Stöckelhuber, Sven Wiessner, Petra Potschke, Gert Heinrich, Amit Das
A detail study concerning the strain (tensile) dependent electrical conductivity of elastomeric composites is reported in this present paper. Multiwall carbon nanotubes (CNT), conducting carbon black (CB) and their combinations were considered as conducting filler in crosslinked natural rubber matrix. The loadings of the fillers were considered from 3 to 11 phr (filler concentration close to their percolation threshold). Without hindering the elastic nature of the composite (reversible stretchability up to several 100 %), the change of relative resistance, ∆R/R (∆R is the change in the resistance with respect to strain and R is the initial resistance of the sample) of the CB filled composites was found to be as much as ~1300 at around 120 % elongation...
January 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28093429/paediatric-ed-bipap-continuous-quality-improvement-programme-with-patient-analysis-2005-2013
#10
Thomas Abramo, Abby Williams, Samaiya Mushtaq, Mark Meredith, Rawle Sepaule, Kristen Crossman, Cheryl Burney Jones, Suzanne Godbold, Zhuopei Hu, Todd Nick
OBJECTIVE: In paediatric moderate-to-severe asthmatics, there is significant bronchospasm, airway obstruction, air trapping causing severe hyperinflation with more positive intraplural pressure preventing passive air movement. These effects cause an increased respiratory rate (RR), less airflow and shortened inspiratory breath time. In certain asthmatics, aerosols are ineffective due to their inadequate ventilation. Bilevel positive airway pressure (BiPAP) in acute paediatric asthmatics can be an effective treatment...
January 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/28093258/stooping-crouching-and-standing-characterizing-balance-control-strategies-across-postures
#11
Tyler B Weaver, Michal N Glinka, Andrew C Laing
BACKGROUND: While stooping and crouching postures are critical for many activities of daily living, little is known about the balance control mechanisms employed during these postures. Accordingly, the purpose of this study was to characterize the mechanisms driving net center of pressure (COPNet) movement across three postures (standing, stooping, and crouching) and to investigate if control in each posture was influenced by time. METHODS: Ten young adults performed the three postures for 60s each...
January 6, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28092813/walking-mechanics-for-patellofemoral-pain-subjects-with-similar-self-reported-pain-levels-can-differ-based-upon-neuromuscular-activation
#12
Matthew K Seeley, S Jun Son, Hyunsoo Kim, J Ty Hopkins
Patellofemoral pain (PFP) is often studied on subjects who are classified using only self-reported data. Neuromuscular activation influences movement mechanics for PFP subjects, but is not likely to be self-reported. We compared lower-extremity mechanics, during a common movement (walking), between two subdivisions of a group of PFP subjects that were similar, based on common self-report tools, but different, based on a common objective measure of quadriceps activation. Our intent was to highlight the importance of objectively considering neuromuscular activation when researching PFP movement mechanics...
January 9, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28092227/the-reliability-of-the-extra-load-index-as-a-measure-of-relative-load-carriage-economy
#13
Sean Hudson, Carlton Cooke, Ray Lloyd
The aim of this study was to measure the reliability of the Extra Load Index (ELI) as a method for assessing relative load carriage economy. Seventeen volunteers (12 males, 5 females) performed walking trials at 3 km(.)h(-1), 6 km(.)h(-1) and a self-selected speed. Trial conditions were repeated 7 days later to assess test-retest reliability. Trials involved four, four-minute periods of walking, each separated by 5 minutes of rest. The initial stage was performed unloaded followed in a randomised order by a second unloaded period and walking with backpacks of 7kg and 20kg...
January 16, 2017: Ergonomics
https://www.readbyqxmd.com/read/28091528/super-emitters-in-natural-gas-infrastructure-are-caused-by-abnormal-process-conditions
#14
Daniel Zavala-Araiza, Ramón A Alvarez, David R Lyon, David T Allen, Anthony J Marchese, Daniel J Zimmerle, Steven P Hamburg
Effectively mitigating methane emissions from the natural gas supply chain requires addressing the disproportionate influence of high-emitting sources. Here we use a Monte Carlo simulation to aggregate methane emissions from all components on natural gas production sites in the Barnett Shale production region (Texas). Our total emission estimates are two-thirds of those derived from independent site-based measurements. Although some high-emitting operations occur by design (condensate flashing and liquid unloadings), they occur more than an order of magnitude less frequently than required to explain the reported frequency at which high site-based emissions are observed...
January 16, 2017: Nature Communications
https://www.readbyqxmd.com/read/28089938/3d-printed-rf-probeheads-for-low-cost-high-throughput-nmr
#15
R Adam Horch, John C Gore
3D printing has been exploited as a means to fabricate complete NMR probeheads containing arrays of miniature RF circuits for high-throughput solution-state NMR spectroscopy and potentially other purposes. 3D-printed NMR circuits of millimeter scale were constructed consisting of RF coils, variable tuning/matching capacitors, and liquid NMR sample cavities. Channels and cavities capable of being addressed using microfluidics are included in the probehead structure, providing a means for hydraulically-controlled RF tuning/matching and liquid NMR sample loading/unloading...
January 12, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28088578/the-effect-of-long-term-hindlimb-unloading-on-the-expression-of-risk-neurogenes-encoding-elements-of-serotonin-dopaminergic-systems-and-apoptosis-comparison-with-the-effect-of-actual-spaceflight-on-mouse-brain
#16
E A Kulikova, V A Kulikov, N A Sinyakova, A V Kulikov, N K Popova
The study of spaceflight effects on the brain is technically complex concern; complicated by the problem of applying an adequate ground model. The most-widely used experimental model to study the effect of microgravity is the tail-suspension hindlimb unloading model; however, its compliance with the effect of actual spaceflight on the brain is still unclear. We evaluated the effect of one month hindlimb unloading on the expression of genes related to the brain neuroplasticity-brain neutotrophic factors (Gdnf, Cdnf), apoptotic factors (Bcl-xl, Bax), serotonin- and dopaminergic systems (5-HT2A, Maoa, Maob, Th, D1r, Comt), and compared the results with the data obtained on mice that spent one month in spaceflight on Russian biosatellite Bion-M1...
January 12, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28087888/simulated-microgravity-decreases-circulating-iron-in-rats-role-of-inflammation-induced-hepcidin-upregulation
#17
Thibault Cavey, Nicolas Pierre, Kévin Nay, Coralie Allain, Martine Ropert, Olivier Loréal, Frédéric Derbré
During spaceflight, humans exposed to microgravity exhibit an increase of iron storage and a reduction of circulating iron. Such perturbations could promote oxidative stress and anemia in astronauts. The mechanism by which microgravity modulates iron metabolism is still unknown. Herein, we hypothesized that microgravity up-regulates hepcidin, a hormone produced by the liver that is the main controller of iron homeostasis. To test this hypothesis, rats were submitted to hindlimb unloading (HU), the reference model to mimic the effects of microgravity in rodents...
January 13, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28078394/kinematics-of-a-bicruciate-retaining-total-knee-arthroplasty
#18
Thomas J Heyse, Joshua Slane, Geert Peersman, Margo Dirckx, Arne van de Vyver, Philipp Dworschak, Susanne Fuchs-Winkelmann, Lennart Scheys
PURPOSE: The recently reintroduced bicruciate-retaining Total Knee Arthroplasty (BCR TKA) is an interesting approach in the quest for close replication of knee joint biomechanics and kinematics closer to the native knee. Therefore, this study aimed at providing a detailed biomechanical view on the functional resemblance of BCR TKA to the native knee joint. METHODS: Seven fresh-frozen full leg cadaver specimens (76 ± 10 year) were mounted in a 6 degrees-of-freedom kinematic rig that applied a dynamic squatting motion knee flexion...
January 11, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28077761/on-the-autorotation-of-animal-wings
#19
Victor Manuel Ortega-Jimenez, Antonio Martín-Alcántara, Ramon Fernandez-Feria, Robert Dudley
Botanical samaras spin about their centre of mass and create vertical aerodynamic forces which slow their rate of descent. Descending autorotation of animal wings, however, has never been documented. We report here that isolated wings from Anna's hummingbirds, and also from 10 species of insects, can stably autorotate and achieve descent speeds and aerodynamic performance comparable to those of samaras. A hummingbird wing loaded at its base with the equivalent of 50% of the bird's body mass descended only twice as fast as an unloaded wing, and rotated at frequencies similar to those of the wings in flapping flight...
January 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28075496/effect-of-dorsal-laminectomy-and-dorsal-annulectomy-with-partial-lumbosacral-discectomy-on-the-volume-of-the-lateral-intervertebral-neuroforamina-in-dogs-when-the-lumbosacral-junction-is-extended
#20
Andrew J Worth, Angela Hartman, Janis P Bridges, Boyd R Jones, Joe I G Mayhew
OBJECTIVE: To determine the effect of dorsal annulectomy and partial discectomy on the volume of the lumbosacral lateral intervertebral neurovascular foramina (intervertebral foramina) in canine cadavers during extension of the lumbosacral junction. STUDY DESIGN: Ex vivo experiment. SAMPLE POPULATION: Lumbosacral specimens from 10 large breed dogs euthanatized for reasons unrelated to lumbosacral disease. METHODS: The lumbosacral specimens were clamped in a wooden jig and scanned using computed tomography (CT) with the lumbosacral junction in a neutral position and loaded in extension using a tensioning device...
January 11, 2017: Veterinary Surgery: VS
keyword
keyword
43267
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"