keyword
https://read.qxmd.com/read/38538674/in-silico-designed-novel-multi-epitope-mrna-vaccines-against-brucella-by-targeting-extracellular-protein-btub-and-lptd
#21
JOURNAL ARTICLE
Juan Shi, Yuejie Zhu, Zhengwei Yin, Yueyue He, Yujiao Li, Gulishati Haimiti, Xinru Xie, Ce Niu, Wenhong Guo, Fengbo Zhang
Brucella, a gram-negative intracellular bacterium, causing Brucellosis, a zoonotic disease with a range of clinical manifestations, from asymptomatic to fever, fatigue, loss of appetite, joint and muscle pain, and back pain, severe patients have developed serious diseases affecting various organs. The mRNA vaccine is an innovative type of vaccine that is anticipated to supplant traditional vaccines. It is widely utilized for preventing viral infections and for tumor immunotherapy. However, research regarding its effectiveness in preventing bacterial infections is limited...
March 27, 2024: Scientific Reports
https://read.qxmd.com/read/38536711/a-magnetic-resonance-conditional-robot-for-lumbar-spinal-injection-development-and-preliminary-validation
#22
JOURNAL ARTICLE
Depeng Liu, Gang Li, Shuyuan Wang, Zixuan Liu, Yanzhou Wang, Laura Connolly, David E Usevitch, Guofeng Shen, Kevin Cleary, Iulian Iordachita
PURPOSE: This work presents the design and preliminary validation of a Magnetic Resonance (MR) conditional robot for lumbar injection for the treatment of lower back pain. METHODS: This is a 4-degree-of-freedom (DOF) robot that is 200 × 230 × 130 mm3 in volume and has a mass of 0.8 kg. Its lightweight and compact features allow it to be directly affixed to patient's back, establishing a rigid connection, thus reducing positional errors caused by patient movements during treatment...
February 2024: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://read.qxmd.com/read/38523940/an-unusual-case-of-non-typhoidal-salmonella-bacteremia-causing-life-threatening-aortitis
#23
Fawwad A Ansari, Stefan Gafoor, Mubashira Aftab, Zola Nlandu
Non-typhoidal Salmonella typically presents with gastroenteritis. However, an invasive Salmonella infection, which may be typically seen in immunocompromised patients, has a propensity for aortic involvement, especially in patients with risk factors for atherosclerosis. Here we present a 60-year-old female with multiple comorbid conditions and currently on immunosuppressants for rheumatoid arthritis, who presented with nausea, vomiting, and fever of three weeks duration and was found to have Salmonella bacteremia...
February 2024: Curēus
https://read.qxmd.com/read/38519304/potential-of-dual-energy-ct-based-collagen-maps-for-the-assessment-of-disk-degeneration-in-the-lumbar-spine
#24
JOURNAL ARTICLE
Scherwin Mahmoudi, Leon D Gruenewald, Vitali Koch, Simon Bernatz, Simon S Martin, Lara Engelskirchen, Ivana Radic, Giuseppe Bucolo, Tommaso D'Angelo, Jennifer Gotta, Christoph Mader, Daniel Pinto Dos Santos, Jan-Erik Scholtz, Tatjana Gruber-Rouh, Katrin Eichler, Thomas J Vogl, Christian Booz, Ibrahim Yel
RATIONALE AND OBJECTIVES: Lumbar disk degeneration is a common condition contributing significantly to back pain. The objective of the study was to evaluate the potential of dual-energy CT (DECT)-derived collagen maps for the assessment of lumbar disk degeneration. PATIENTS AND METHODS: We conducted a retrospective analysis of 127 patients who underwent dual-source DECT and MRI of the lumbar spine between 07/2019 and 10/2022. The level of lumbar disk degeneration was categorized by three radiologists as follows: no/mild (Pfirrmann 1&2), moderate (Pfirrmann 3&4), and severe (Pfirrmann 5)...
March 21, 2024: Academic Radiology
https://read.qxmd.com/read/38512737/mri-compatible-lumbopelvic-movement-measurement-system-to-validate-and-capture-task-performance-during-neuroimaging
#25
JOURNAL ARTICLE
Ahyoung Song, Kerrigan Sunday, Sheri P Silfies, Jennifer Mc Vendemia
Research suggests that structural and functional changes within the brain are associated with chronic low back pain, and these cortical alterations might contribute to impaired sensorimotor control of the trunk and hips in this population. However, linking sensorimotor brain changes with altered movement of the trunk and hips during task-based neuroimaging presents significant challenges. An MRI-safe pressure measurement system was developed to ensure proper task completion during neuroimaging by capturing movement patterns of the trunk (sensors under the lower back) and hips (sensors embedded in the foam roll under the knees)...
March 21, 2024: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://read.qxmd.com/read/38493893/short-term-clinical-and-radiographic-evaluation-of-patients-treated-with-expandable-and-static-interbody-spacers-following-lumbar-lateral-interbody-fusion
#26
JOURNAL ARTICLE
Yawara Eguchi, Noritaka Suzuki, Sumihisa Orita, Kazuhide Inage, Miyako Narita, Yasuhiro Shiga, Masahiro Inoue, Noriyasu Toshi, Soichiro Tokeshi, Kohei Okuyama, Shuhei Ohyama, Satoshi Maki, Yasuchika Aoki, Junichi Nakamura, Shigeo Hagiwara, Yuya Kawarai, Tsutomu Akazawa, Masao Koda, Hiroshi Takahashi, Seiji Ohtori
OBJECTIVE: The goal of this study was to evaluate, using computed tomography (CT) and magnetic resonance imaging (MRI), patients who underwent oblique lateral interbody fusion (OLIF) using either expandable or static interbody spacers. METHODS: Thirty-five patients with degenerative disc disease were surgically treated with one-level OLIF and were followed up for more than six months. The Static group consisted of 22 patients, and 13 patients were in the Expandable group...
March 15, 2024: World Neurosurgery
https://read.qxmd.com/read/38478495/are-clinically-unimportant-findings-qualified-as-benign-in-lumbar-spine-imaging-reports-a-content-analysis-of-plain-x-ray-ct-and-mri-reports
#27
JOURNAL ARTICLE
Caitlin Farmer, Romi Haas, Jason Wallis, Denise O'Connor, Rachelle Buchbinder
BACKGROUND: Lumbar spine diagnostic imaging reports may cause patient and clinician concern when clinically unimportant findings are not explicitly described as benign. Our primary aim was to determine the frequency that common, benign findings are reported in lumbar spine plain X-ray, computed tomography (CT) and magnetic resonance imaging (MRI) reports as either normal for age or likely clinically unimportant. METHODS: We obtained 600 random de-identified adult lumbar spine imaging reports (200 X-ray, 200 CT and 200 MRI) from a large radiology provider...
2024: PloS One
https://read.qxmd.com/read/38473083/advances-in-the-clinical-diagnostics-to-equine-back-pain-a-review-of-imaging-and-functional-modalities
#28
REVIEW
Natalia Domańska-Kruppa, Małgorzata Wierzbicka, Elżbieta Stefanik
Back pain is common in ridden horses. Back diseases in horses include Impinging Dorsal Spinous Processes, Ventral Spondylosis, Osteoarthritis of Articular Process, Intervertebral Discs Disease, Vertebral Fractures, Conformational Abnormalities, Desmopathy of the Supraspinous Ligament, Desmopathy of the Intraspinous Ligament, and Longissimus Muscle Strain. Back pain may also develop as a result of lameness (particularly hindlimb lameness). A poorly fitting saddle and an unbalanced rider are also considered important factors influencing the development of back pain in horses...
February 23, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38468846/disseminated-histoplasmosis-infection-diagnosed-by-metagenomic-next-generation-sequencing-a-case-report
#29
Lei Qiang, Xianghui Deng, Yong Yang, Zhigan Wang, Wei Gai
Histoplasmosis is an endemic disease caused by Histoplasma capsulatum . This systemic disease can affect various organs beyond the lungs, such as the liver, spleen, adrenal gland, and lymph nodes. The clinical symptoms can range from asymptomatic to severe, life-threatening conditions, depending on the state of the patient's immune system. This report describes a 40-year-old male who presented with reports of weight loss, low back pain, and progressively worsening movement disorder of the bilateral lower extremities for months...
2024: Infection and Drug Resistance
https://read.qxmd.com/read/38467047/oblique-anterior-column-realignment-with-a-mini-open-posterior-column-osteotomy-for-minimally-invasive-adult-spinal-deformity-correction-illustrative-case
#30
JOURNAL ARTICLE
Zach Pennington, Nolan J Brown, Seyedamirhossein Pishva, Hernán F J González, Martin H Pham
BACKGROUND: Adult spinal deformity (ASD) occurs from progressive anterior column collapse due to disc space desiccation, compression fractures, and autofusion across disc spaces. Anterior column realignment (ACR) is increasingly recognized as a powerful tool to address ASD by progressively lengthening the anterior column through the release of the anterior longitudinal ligament during lateral interbody approaches. Here, we describe the application of minimally invasive ACR through an oblique antepsoas corridor for deformity correction in a patient with adult degenerative scoliosis and significant sagittal imbalance...
March 11, 2024: J Neurosurg Case Lessons
https://read.qxmd.com/read/38465202/how-people-with-persistent-pain-experience-in-person-physiotherapy-blended-with-biopsychosocial-digital-health-a-qualitative-study-on-participants-experiences-with-back2action
#31
JOURNAL ARTICLE
E Y Poolman, L Vorstermans, M H Donker, L Bijker, M W Coppieters, P Cuijpers, G G M Scholten-Peeters, L M de Wit
BACKGROUND: A blended intervention consisting of in-person physiotherapy and psychologically-informed digital health, called Back2Action, was developed to optimise the management of people with persistent spinal pain who also have psychosocial risk factors associated with the development or maintenance of persistent pain. This study aimed to gain insights in how participants experienced this blended intervention. METHODS: A qualitative study using semi-structured interviews was conducted...
June 2024: Internet Interventions
https://read.qxmd.com/read/38463472/an-unusual-case-of-maxillary-first-molar-with-seven-canals-and-the-successful-surgical-recovery-of-a-separated-instrument
#32
Shubhangi Kadoo, Pallav Mahesh Patni, Pradeep Jain, Nikit Agrawal, Swadhin Raghuwanshi, Sanket Hans Pandey
This case report highlights the intricate anatomy of root canals and the challenges they pose for clinicians. A 26-year-old female patient presented to the department with a chief complaint of pain in her left upper back tooth region. After thorough clinical and radiographical examinations, the diagnosis of pulpal necrosis with symptomatic apical periodontitis in the maxillary left first molar was confirmed. An intraoperative cone-beam computed tomography was performed. The axial imaging unveiled that there were, two distal (DB1 and DB2) canals, two palatal (P1 and P2) canals, and three mesiobuccal (MB1, MB2, and MB3) canals...
February 2024: J Conserv Dent Endod
https://read.qxmd.com/read/38462827/magnetic-resonance-images-segmentation-of-multifidus-based-on-dense-unet-and-superpixel
#33
JOURNAL ARTICLE
Rui Xu, Xin Guo, Zimin Wang, Tingqiang Guan, Yue Zhou
BACKGROUND: Lumbar disc herniation (LDH) is a common clinical condition causing lower back and leg pain. Accurate segmentation of the lumbar discs is crucial for assessing and diagnosing LDH. Magnetic resonance imaging (MRI) can reveal the condition of articular cartilage. However, manual segmentation of MRI images is burdensome for physicians and needs to be more efficient. OBJECTIVE: In this study, we propose a method that combines UNet and superpixel segmentation to address the problem of loss of detailed information in the feature extraction phase, leading to poor segmentation results at object edges...
March 7, 2024: Current medical imaging
https://read.qxmd.com/read/38462073/the-first-reported-pulmonary-nocardiosis-caused-by-nocardia-gipuzkoensis-resisted-to-tmp-smz-in-an-immunocompetent-patient
#34
JOURNAL ARTICLE
Yishan Duan, Xiaoxia Zhang, Wen Deng, Suyan Wang, Jinrui Hu, Xiaohui Wang, Weimin Li, Bojiang Chen
BACKGROUND: . Nocardia gipuzkoensis was first described as a novel and distinct species in 2020 by Imen Nouioui and pulmonary nocardiosis associated with Nocardia gipuzkoensis was once reported in two bronchiectasis patients. Noteworthy, both reported Nocardia gipuzkoensis cases showed sensitivity to Trimethoprim/Sulfamethoxazol (TMP-SMZ), which are usually recommended for empirical therapy. METHODS: We reported the third case of Nocardia gipuzkoensis infection in a 16-year-old girl with chief complaints of cough, persistent chest and back pain...
March 8, 2024: Journal of Global Antimicrobial Resistance
https://read.qxmd.com/read/38459858/-surgical-treatment-for-ruptured-thoracoabdominal-aneurysm-following-descending-aortic-replacement-with-double-barrel-anastomosis
#35
JOURNAL ARTICLE
Shuichi Okada, Masahiko Ezure, Yutaka Hasegawa, Yasuyuki Yamada, Joji Hoshino, Hiroyuki Morishita, Masahiro Seki, Kazuki Tamura, Takashi Soda
A 75-year-old woman was diagnosed with type B acute aortic dissection 14 years ago and 3-channeled aortic dissection 7 years ago. She received total arch replacement 6 years ago and descending aortic replacement with double barrel anastomosis technique for distal anastomosis 5 years ago. Computed tomography( CT) revealed giant thyroid tumor and thoracoabdominal aortic aneurysm( 58 mm in diameter). She suffered from back pain during her follow-up period. CT revealed ruptured thoracoabdominal aortic aneurysm...
February 2024: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://read.qxmd.com/read/38452472/automated-entry-of-paper-based-patient-reported-outcomes-applying-deep-learning-to-the-japanese-orthopaedic-association-back-pain-evaluation-questionnaire
#36
JOURNAL ARTICLE
Kosuke Kita, Takahito Fujimori, Yuki Suzuki, Takashi Kaito, Shota Takenaka, Yuya Kanie, Masayuki Furuya, Tomohiro Wataya, Daiki Nishigaki, Junya Sato, Noriyuki Tomiyama, Seiji Okada, Shoji Kido
BACKGROUND: Health-related patient-reported outcomes (HR-PROs) are crucial for assessing the quality of life among individuals experiencing low back pain. However, manual data entry from paper forms, while convenient for patients, imposes a considerable tallying burden on collectors. In this study, we developed a deep learning (DL) model capable of automatically reading these paper forms. METHODS: We employed the Japanese Orthopaedic Association Back Pain Evaluation Questionnaire, a globally recognized assessment tool for low back pain...
February 19, 2024: Computers in Biology and Medicine
https://read.qxmd.com/read/38445259/esophageal-perforation-by-fish-bone-ingestion-causing-purulent-pericarditis
#37
Tamara Arruda, Vinícius Nina, Nilo Souza Filho, Aubyn Marath, João Pedro Abreu
A previously healthy 38-year-old woman presented with new-onset sudden chest pain radiating to the back, associated with cough, dyspnea, nausea, vomiting, and gastric fullness after eating a bony fish. A diagnosis of gastroesophageal reflux disease was made. After a week of progressive worsening of her symptoms, she was referred to the specialist hospital. There, computed tomography imaging strongly suggested that a likely fishbone had penetrated the esophagus into the mediastinal structures; it seemed to have produced a pneumopericardium...
March 2024: ACG Case Reports Journal
https://read.qxmd.com/read/38442912/early-clinical-and-radiological-evaluation-of-unilateral-biportal-endoscopic-unilateral-laminotomy-bilateral-decompression-in-degenerative-lumbar-spinal-stenosis-a-retrospective-study
#38
JOURNAL ARTICLE
Yin Jianjian, Tao Ma, Gongming Gao, Qi Chen, Luming Nong
PURPOSE: To evaluate changes in radiological parameters and clinical outcomes following unilateral biportal endoscopic unilateral laminotomy bilateral decompression for treatment of central lumbar spinal stenosis. METHODS: Forty-one central lumbar spinal stenosis patients who underwent unilateral biportal endoscopic unilateral laminotomy bilateral decompression (UBE ULBD) were enrolled from April 2021 to February 2023. Visual analog scale (VAS) back pain, VAS leg pain, Oswestry Disability Index (ODI) score and the modified MacNab criteria were assessed preoperatively, postoperatively...
March 5, 2024: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://read.qxmd.com/read/38440706/parenchymal-renal-rupture-due-to-an-obstructive-ureteric-calculus-in-an-incompletely-duplicated-renal-pelvis-and-ureter
#39
Moe Toyoshima, Daiki Ikarashi, Kie Sekiguchi, Tatsuya Kawamura, Arisa Machida, Takeshi Yamaguchi, Yumeka Arakawa, Akito Ito, Shigekatsu Maekawa, Wataru Obara
INTRODUCTION: Parenchymal renal rupture due to a ureteric calculus is extremely rare and an emergency. CASE PRESENTATION: A 54-year-old man was brought to the emergency room with left back pain without trauma. Computed tomography showed left parenchymal renal rupture with an incompletely duplicated renal pelvis, ureter, and an 11-mm ureteric calculus in the ureterovesical junction. A ureteral stent was placed, and the patient was treated conservatively as his vital signs were stable...
March 2024: IJU case reports
https://read.qxmd.com/read/38440020/staphylococcus-aureus-bacteremia-with-disseminated-multiple-foci-and-pyomyositis-in-an-immunocompetent-patient-a-case-report
#40
Ryohei Ono, Izumi Kitagawa
Pyomyositis is an uncommon primary infection of skeletal muscle resulting in muscle inflammation followed by pus formation. Pyomyositis is typically caused by Staphylococcus aureus (S. aureus), and most cases are associated with skin penetration and/or immunosuppressive conditions in tropical or even temperate climates. We report a previously healthy, immunocompetent 44-year-old man who presented with fever and right lower back pain. He had received an analgesic injection for his back pain 12 days prior to this visit...
February 2024: Curēus
keyword
keyword
43263
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.