keyword
https://read.qxmd.com/read/38536727/increasing-reciprocal-social-interactions-between-children-who-use-augmentative-and-alternative-communication-and-peers-using-a-collaborative-learning-framework
#1
JOURNAL ARTICLE
Jamie B Boster, Tori Cordone, Hailey Blosser
PURPOSE: Children with complex communication needs who rely on augmentative and alternative communication (AAC) strategies to express themselves face significant difficulties interaction with peers. This study sought to design, implement, and evaluate a collaborative photography intervention designed to increase reciprocal social interaction between children who use AAC and their same-age peers. METHOD: A single-subject, withdrawal design (ABAB) was used to explore the functional relationship between engagement in a collaborative photography intervention and the frequency of reciprocal social interactions between children who use AAC and their same-age peers...
March 27, 2024: American Journal of Speech-language Pathology
https://read.qxmd.com/read/38535373/mapping-and-characterization-of-target-site-resistance-to-cyclic-ketoenol-insecticides-in-cabbage-whiteflies-aleyrodes-proletella-hemiptera-aleyrodidae
#2
JOURNAL ARTICLE
Viola Müller, Frank Maiwald, Gudrun Lange, Ralf Nauen
Cabbage whitefly, Aleyrodes proletella L., is an invasive hemipteran pest of cruciferous plants, particularly field brassica crops. Its importance has been increased over the last decade, particularly in European countries. The control of cabbage whiteflies largely relies on the application of synthetic insecticides, including tetronic and tetramic acid derivatives such as spiromesifen and spirotetramat (cyclic ketoenol insecticides), acting as insect growth regulators targeting acetyl-CoA carboxylase (ACC)...
March 6, 2024: Insects
https://read.qxmd.com/read/38535294/the-research-progress-on-the-interaction-between-mammalian-gut-microbiota-and-the-host-s-metabolism-homeostasis-during-hibernation
#3
REVIEW
Zhepei Zhang, Fengcheng Song, Linjuan Wang, Zhengrong Yuan
Hibernating mammals confront seasonal and harsh environmental shifts, prompting a cycle of pre-hibernation feeding and subsequent winter fasting. These adaptive practices induce diverse physiological adjustments within the animal's body. With the gut microbiota's metabolic activity being heavily reliant on the host's diet, this cycle's primary impact is on this microbial community. When the structure and composition of the gut microbiota changes, corresponding alterations in the interactions occur between these microorganisms and their host...
February 21, 2024: Metabolites
https://read.qxmd.com/read/38534763/unveiling-the-ovarian-cell-characteristics-and-molecular-mechanism-of-prolificacy-in-goats-via-single-nucleus-transcriptomics-data-analysis
#4
JOURNAL ARTICLE
Sanbao Zhang, Yirong Wei, Xiaotong Gao, Ying Song, Yanna Huang, Qinyang Jiang
Increases in litter size, which are influenced by ovulation, are responsible for between 74% and 96% of the economic value of genetic progress, which influences selection. For the selection and breeding of highly prolific goats, genetic mechanisms underlying variations in litter size should be elucidated. Here, we used single-nucleus RNA sequencing to analyze 44,605 single nuclei from the ovaries of polytocous and monotocous goats during the follicular phase. Utilizing known reference marker genes, we identified 10 ovarian cell types characterized by distinct gene expression profiles, transcription factor networks, and reciprocal interaction signatures...
March 11, 2024: Current Issues in Molecular Biology
https://read.qxmd.com/read/38533662/neural-circuits-underlying-reciprocal-cardiometabolic-crosstalk-2023-arthur-c-corcoran-memorial-lecture
#5
REVIEW
Kamal Rahmouni
The interplay of various body systems, encompassing those that govern cardiovascular and metabolic functions, has evolved alongside the development of multicellular organisms. This evolutionary process is essential for the coordination and maintenance of homeostasis and overall health by facilitating the adaptation of the organism to internal and external cues. Disruption of these complex interactions contributes to the development and progression of pathologies that involve multiple organs. Obesity-associated cardiovascular risks, such as hypertension, highlight the significant influence that metabolic processes exert on the cardiovascular system...
March 27, 2024: Hypertension
https://read.qxmd.com/read/38532924/high-energy-electron-diffraction-instrument-with-tunable-camera-length
#6
JOURNAL ARTICLE
P Denham, Y Yang, V Guo, A Fisher, X Shen, T Xu, R J England, R K Li, P Musumeci
Ultrafast electron diffraction (UED) stands as a powerful technique for real-time observation of structural dynamics at the atomic level. In recent years, the use of MeV electrons from radio frequency guns has been widely adopted to take advantage of the relativistic suppression of the space charge effects that otherwise limit the temporal resolution of the technique. Nevertheless, there is not a clear choice for the optimal energy for a UED instrument. Scaling to beam energies higher than a few MeV does pose significant technical challenges, mainly related to the inherent increase in diffraction camera length associated with the smaller Bragg angles...
March 2024: Structural Dynamics (Melville, N.Y.)
https://read.qxmd.com/read/38532410/wnt5a-%C3%AE-catenin-mediated-epithelial-mesenchymal-transition-a-key-driver-of-subretinal-fibrosis-in-neovascular-age-related-macular-degeneration
#7
JOURNAL ARTICLE
Dandan Liu, Jingxiao Du, Hai Xie, Haibin Tian, Lixia Lu, Chaoyang Zhang, Guo-Tong Xu, Jingfa Zhang
BACKGROUND: Neovascular age-related macular degeneration (nAMD), accounts for up to 90% of AMD-associated vision loss, ultimately resulting in the formation of fibrotic scar in the macular region. The pathogenesis of subretinal fibrosis in nAMD involves the process of epithelial-mesenchymal transition (EMT) occurring in retinal pigment epithelium (RPE). Here, we aim to investigate the underlying mechanisms involved in the Wnt signaling during the EMT of RPE cells and in the pathological process of subretinal fibrosis secondary to nAMD...
March 26, 2024: Journal of Neuroinflammation
https://read.qxmd.com/read/38532014/dip-ms-ultra-deep-interaction-proteomics-for-the-deconvolution-of-protein-complexes
#8
JOURNAL ARTICLE
Fabian Frommelt, Andrea Fossati, Federico Uliana, Fabian Wendt, Peng Xue, Moritz Heusel, Bernd Wollscheid, Ruedi Aebersold, Rodolfo Ciuffa, Matthias Gstaiger
Most proteins are organized in macromolecular assemblies, which represent key functional units regulating and catalyzing most cellular processes. Affinity purification of the protein of interest combined with liquid chromatography coupled to tandem mass spectrometry (AP-MS) represents the method of choice to identify interacting proteins. The composition of complex isoforms concurrently present in the AP sample can, however, not be resolved from a single AP-MS experiment but requires computational inference from multiple time- and resource-intensive reciprocal AP-MS experiments...
March 26, 2024: Nature Methods
https://read.qxmd.com/read/38530327/the-spiraling-cognitive-emotional-brain-combinatorial-reciprocal-and-reentrant-macro-organization
#9
JOURNAL ARTICLE
Luiz Pessoa
This article proposes a framework for understanding the macro-scale organization of anatomical pathways in the mammalian brain. The architecture supports flexible behavioral decisions across a spectrum of spatio-temporal scales. The proposal emphasizes the combinatorial, reciprocal, and reentrant connectivity-called CRR neuroarchitecture-between cortical, BG, thalamic, amygdala, hypothalamic, and brainstem circuits. Thalamic nuclei, especially midline/intralaminar nuclei, are proposed to act as hubs routing the flow of signals between noncortical areas and pFC...
March 22, 2024: Journal of Cognitive Neuroscience
https://read.qxmd.com/read/38529525/a-socioemotional-network-perspective-on-momentary-experiences-of-family-conflict-in-young-adults
#10
JOURNAL ARTICLE
Xinyi Wang, Amanda L McGowan, Gregory M Fosco, Emily B Falk, Dani S Bassett, David M Lydon-Staley
Family conflict is an established predictor of psychopathology in youth. Traditional approaches focus on between-family differences in conflict. Daily fluctuations in conflict within families might also impact psychopathology, but more research is needed to understand how and why. Using 21 days of daily diary data and 6-times a day experience-sampling data (N = 77 participants; mean age = 21.18, SD = 1.75; 63 women, 14 men), we captured day-to-day and within-day fluctuations in family conflict, anger, anxiety, and sadness...
March 26, 2024: Family Process
https://read.qxmd.com/read/38528090/enhanced-dye-removal-using-montmorillonite-modified-with-graphene-quantum-dots-in-sustainable-salep-nanocomposite-hydrogel
#11
JOURNAL ARTICLE
Kolsum Mohammad Sharifi, Ahmad Poursattar Marjani, Peyman Gozali Balkanloo
This research investigated the utilization of graphene quantum dot/montmorillonite (GQD/MMT) as an effective nanofiller in a hydrogel composed of salep biopolymer. The semi-IPN hydrogel was synthesized using salep as the substrate, acrylamide (AAm) as the monomer, ammonium persulfate (APS) as an initiator in free radical polymerization, and N,N'-methylenebisacrylamide (MBA) as a cross-linking agent. The hydrogels were applied to remove safranin (SA), methylene blue (MB), crystal violet (CV), methyl green (MG), congo red (CR), and malachite green (MG) dyes from the water...
March 25, 2024: Scientific Reports
https://read.qxmd.com/read/38527649/variation-in-the-effectiveness-of-reinforcement-and-nonreinforcement-in-generating-different-conditioned-behaviors
#12
JOURNAL ARTICLE
Victor Navarro, Dominic M Dwyer, Robert C Honey
Rat autoshaping procedures generate two readily measurable conditioned responses: During lever presentations that have previously signaled food, rats approach the food well (called goal-tracking) and interact with the lever itself (called sign-tracking). We investigated how reinforced and nonreinforced trials affect the overall and temporal distributions of these two responses across 10-second lever presentations. In two experiments, reinforced trials generated more goal-tracking than sign-tracking, and nonreinforced trials resulted in a larger reduction in goal-tracking than sign-tracking...
March 23, 2024: Neurobiology of Learning and Memory
https://read.qxmd.com/read/38527204/ligand-induced-protein-transition-state-stabilization-switches-the-binding-pathway-from-conformational-selection-to-induced-fit
#13
JOURNAL ARTICLE
Olof Stenström, Carl Diehl, Kristofer Modig, Mikael Akke
Protein-ligand complex formation is fundamental to biological function. A central question is whether proteins spontaneously adopt binding-competent conformations to which ligands bind conformational selection (CS) or whether ligands induce the binding-competent conformation induced fit (IF). Here, we resolve the CS and IF binding pathways by characterizing protein conformational dynamics over a wide range of ligand concentrations using NMR relaxation dispersion. We determined the relative flux through the two pathways using a four-state binding model that includes both CS and IF...
April 2, 2024: Proceedings of the National Academy of Sciences of the United States of America
https://read.qxmd.com/read/38525753/moderating-effect-of-muscular-strength-in-the-association-between-cardiovascular-events-and-depressive-symptoms-in-middle-aged-and-older-adults-a-cross-sectional-study
#14
JOURNAL ARTICLE
Diogo Veiga, Miguel Peralta, Élvio R Gouveia, Marcelo de Maio Nascimento, Laura Carvalho, Jorge Encantado, Adilson Marques
BACKGROUND: Depression and cardiovascular diseases are two main health conditions contributing to the global disease burden. Several studies indicate a reciprocal association between them. It is still unclear how changes in overall muscle strength may impact this association. This study aimed to analyse how muscular strength moderates the relationship between cardiovascular events and depressive symptoms among middle-aged and older adults. METHODS: Wave 8 of the population-based Survey of Health, Ageing, and Retirement in Europe (2019/2020) cross-sectional data, which included 41,666 participants (17,986 men) with a mean age of 70...
March 12, 2024: Geriatrics
https://read.qxmd.com/read/38525454/objective-assessment-of-fatigue-among-aviation-personnel-using-a-bio-mathematical-model-an-experimental-study
#15
JOURNAL ARTICLE
Sudhanshu Shekhar Mohapatra, Biswajit Sinha, Niraj Kumar Tripathy, Devdeep Ghosh
BACKGROUND: There are many subjective and objective tools to detect, assess, and quantify fatigue. This study is a novice attempt to assess the occupational fatigue among the aviation personnel employing a computerized work-rest schedule tool integrated with actigraphy. METHODS: Thirty-eight aviation personnel were assessed for their sleep by using an actigraphy device. A work-rest scheduling software program called Fatigue Avoidance Scheduling Tool (FAST) was used to obtain fatigue parameters like Fatigue Risk Time (FRT), Fatigue Free Time (FFT), and Fatigue Free Occupational Time (FFOT)...
2024: Medical Journal, Armed Forces India
https://read.qxmd.com/read/38524962/development-and-content-validation-of-a-measure-to-assess-the-parent-child-social-emotional-reciprocity-of-children-with-asd
#16
JOURNAL ARTICLE
Asmita Nayak, Rooplekha Khuntia
BACKGROUND: As no scales are currently available to assess the social-emotional reciprocity (SER) between children with autism spectrum disorder (ASD) and their parents, we aimed to develop a questionnaire for this. METHODS: Both quantitative and qualitative techniques were used for content validation. All stages of this study used purposive sampling to choose various groups of experts, mental health professionals, and parents of children with ASD to participate in the development, judgment-quantifying, and pretest stages...
January 2024: Indian Journal of Psychological Medicine
https://read.qxmd.com/read/38524683/lake-water-chemistry-and-local-adaptation-shape-nacl-toxicity-in-daphnia-ambigua
#17
JOURNAL ARTICLE
Mary A Rogalski, Elizabeth S Baker, Clara M Benadon, Christoph Tatgenhorst, Brady R Nichols
The increasing application of road deicing agents (e.g., NaCl) has caused widespread salinization of freshwater environments. Chronic exposure to toxic NaCl levels can impact freshwater biota at genome to ecosystem scales, yet the degree of harm caused by road salt pollution is likely to vary among habitats and populations. The background ion chemistry of freshwater environments may strongly impact NaCl toxicity, with greater harm occurring in ion-poor, soft water conditions. In addition, populations exposed to salinization may evolve increased NaCl tolerance...
March 2024: Evolutionary Applications
https://read.qxmd.com/read/38524571/a-social-network-analysis-of-college-students-online-learning-during-the-epidemic-era-a-triadic-reciprocal-determinism-perspective
#18
REVIEW
Jun Chai, Jian-Hong Ye
The way in which college students learn online has dramatically altered due to the COVID-19 pandemic. Using the triadic reciprocal determinism (TRD) theory, this study aimed to identify the key factors influencing college students' online learning experience through sentiment analysis, text mining, and social network analysis (SNA). Macro- and micro-level parsing was conducted on the SNA model, which was divided into core, mantle, and shell layers to determine the most influential factors in the core layer...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38524561/exploration-of-therapeutic-models-for-psycho-cardiology-from-cardiac-to-psychological-rehabilitation
#19
REVIEW
Yu Ren, Huilin Tang, Liwei Zhang, Chenfei Ying, Hua Luo
The prevalence and mortality of cardiovascular disease are relatively high. Currently, depression has been proven to be an independent risk factor for the occurrence and poor prognosis of cardiovascular disease. Psycho-cardiovascular comorbidity, as a reciprocal cause and effect, affects each other, leading to the deterioration of clinical prognosis and forming a vicious circle. Coronary artery disease comorbidity with depression is a common disease in psycho-cardiology medicine. This paper expounds on the exploration of the treatment model of psycho-cardiology from the aspects of epidemiological characteristics, comorbidity mechanism, screening, diagnosis, and treatment...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38524538/impact-of-the-addition-of-dexmedetomidine-to-patient-controlled-intravenous-analgesia-on-postoperative-pain-sleep-interaction-cycle-and-delirium-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#20
JOURNAL ARTICLE
Wenjie Xu, Yuxiang Zheng, Qing Wang, Zizheng Suo, Lingling Fang, Jing Yang, Shuai Li, Peng Li, Xixi Jia, Xiaoyan Liu, Hui Zheng, Cheng Ni
BACKGROUND: The reciprocal nexus between sleep and pain is well-documented, with the deleterious impact of operative trauma potentially playing a pivotal role in the dysregulation of this interplay, which could significantly contribute to the manifestation of postoperative delirium (POD). Studies have investigated the effect of adding dexmedetomidine (DEX) to patient-controlled intravenous analgesia (PCIA) pumps on postoperative pain-sleep interaction cycle and POD, but conclusions remained uncertain...
March 30, 2024: Heliyon
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