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https://www.readbyqxmd.com/read/28820309/advanced-cone-beam-ct-venous-angiographic-imaging
#1
Visish M Srinivasan, Gouthami Chintalapani, Edward A M Duckworth, Peter Kan
OBJECTIVE The evaluation of the venous neurovasculature, especially the dural venous sinuses, is most often performed using MR or CT venography. For further assessment, diagnostic cerebral angiography may be performed. Three-dimensional rotational angiography (3D-RA) can be applied to the venous system, producing 3D rotational venography (3D-RV) and cross-sectional reconstructions, which function as an adjunct to traditional 2D digital subtraction angiography. METHODS After querying the database of Baylor St...
August 18, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28816935/perimesencephalic-nonaneurysmal-subarachnoid-hemorrhage-caused-by-transverse-sinus-thrombosis-a-case-report-and-review-of-literature
#2
Fang-Wang Fu, Jie Rao, Yuan-Yuan Zheng, Liang Song, Wei Chen, Qi-Hui Zhou, Jian-Guang Yang, Jiang-Qiong Ke, Guo-Qing Zheng
RATIONALE: Perimesencephalic nonaneurysmal subarachnoid hemorrhage (PNSAH) is characterized by a pattern of extravasated blood restricted to the perimesencephalic cisterns, normal angiographic findings, and an excellent prognosis with an uneventful course and low risks of complication. The precise etiology of bleeding in patients with PNSAH has not yet been established. The most common hypothesis is that PNSAH is venous in origin. Intracranial venous hypertension has been considered as the pivotal factor in the pathogenesis of PNSAH...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28814594/concomitant-carotid-aplasia-and-basilar-artery-occlusion-in-a-child-with-phaces-syndrome
#3
Noel Delgado, Jason J Carroll, Philip M Meyers
We report a case of an 8-year-old girl with posterior fossa abnormalities, haemangioma, arterial lesions, cardiac abnormalities or coarctation of the aorta and eye abnormalities syndrome with right carotid aplasia and complete basilar occlusion. The patient initially presented at 2.5 weeks of age with a growing right facial haemangioma involving segments 1, 3 and 4. Initial MRI at 2.5 weeks of age revealed an extraconal right orbital haemangioma without posterior fossa abnormalities and MR angiography (MRA) 3 weeks later showed right internal carotid aplasia...
August 16, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28806383/subependymal-heterotopia-mimicking-mass-in-conventional-magnetic-resonance-imaging-demonstration-with-3t-advanced-neuroimages
#4
Filiz Aktas, Hayri Ogul
The authors reported a rare patient with large subependymal heterotopia mimicking cerebral neoplasia. A 22-year-old female was admitted with a history of right-sided paresthesia accompanied by progressive headache. Cerebral magnetic resonance (MR) imaging showed a large solid lesion in the left frontal lobe. Advanced MR images proved that the lesion was compatible with subependymal heterotopia. Large subependymal heterotopia may mimick cerebral neoplasia.
August 10, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28805936/characterizing-hypoxia-in-human-glioma-a-simultaneous-multimodal-mri-and-pet-study
#5
Christine Preibisch, Kuangyu Shi, Anne Kluge, Mathias Lukas, Benedikt Wiestler, Jens Göttler, Jens Gempt, Florian Ringel, Mohamed Al Jaberi, Jürgen Schlegel, Bernhard Meyer, Claus Zimmer, Thomas Pyka, Stefan Förster
Hypoxia plays an important role for the prognosis and therapy response of cancer. Thus, hypoxia imaging would be a valuable tool for pre-therapeutic assessment of tumor malignancy. However, there is no standard validated technique for clinical application available yet. Therefore, we performed a study in 12 patients with high-grade glioma, where we directly compared the two currently most promising techniques, namely the MR-based relative oxygen extraction fraction (MR-rOEF) and the PET hypoxia marker H-1-(3-[(18) F]-fluoro-2-hydroxypropyl)-2-nitroimidazole ([(18) F]-FMISO)...
August 14, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28802988/does-education-play-a-role-in-language-reorganization-after-surgery-in-drug-refractory-temporal-lobe-epilepsy-an-fmri-based-study
#6
Kapil Chaudhary, Bhargavi Ramanujam, S Senthil Kumaran, P Sarat Chandra, Ashima Nehra Wadhawan, Ajay Garg, Manjari Tripathi
OBJECTIVES: Patients with drug refractory epilepsy (DRE) and a high level of education may differ in their language recovery after surgery. Our aim was to determine whether there were differences in the extent of improvement and pattern of reorganization of language functions on functional magnetic resonance imaging (fMRI) after surgery to treat refractory temporal lobe epilepsy (TLE) between patients with more than 12 years of formal education versus those with a shorter period of regular schooling...
July 29, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28799861/absence-of-cortical-vein-opacification-is-associated-with-lack-of-intra-arterial-therapy-benefit-in-stroke
#7
Ivo G H Jansen, Annemieke B van Vuuren, Wim H van Zwam, Ido R van den Wijngaard, Olvert A Berkhemer, Hester F Lingsma, Cornelis H Slump, Robert J van Oostenbrugge, Kilian M Treurniet, Diederik W J Dippel, Marianne A A van Walderveen, Aad van der Lugt, Yvo B W E M Roos, Henk A Marquering, Charles B L M Majoie, René van den Berg
Purpose To assess the degree of cortical vein opacification in patients with internal carotid artery or middle cerebral artery (MCA) stroke and to evaluate the relationship with treatment benefit from intra-arterial therapy (IAT). Materials and Methods Written informed consent was obtained from all patients in the Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands. From the trial's database, all patients (recruited from December 2010 until March 2014) with baseline computed tomographic (CT) angiograms were retrospectively included...
August 11, 2017: Radiology
https://www.readbyqxmd.com/read/28796443/relative-cerebral-blood-volume-is-a-potential-biomarker-in-late-delayed-radiation-induced-brain-injury
#8
Ying Xie, Haiwei Huang, Junjie Guo, Dongxiao Zhou
PURPOSE: To assess whether relative cerebral blood volume (rCBV) can provide information to reliably evaluate the stages of late delayed radiation-induced brain injury. MATERIALS AND METHODS: Forty patients diagnosed with late delayed radiation-induced brain injury were enrolled. The patients were examined using a 1.5T magnetic resonance imaging (MRI) system equipped with an 8-channel head coil. An echo planar imaging (EPI) sequence was used in perfusion-weighted imaging (PWI)...
August 10, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28796397/clinical-evaluation-of-time-of-flight-mr-angiography-with-sparse-undersampling-and-iterative-reconstruction-for-cerebral-aneurysms
#9
Yasutaka Fushimi, Tomohisa Okada, Takayuki Kikuchi, Akira Yamamoto, Tsutomu Okada, Takayuki Yamamoto, Michaela Schmidt, Kazumichi Yoshida, Susumu Miyamoto, Kaori Togashi
Compressed sensing (CS) MRI has just been introduced to research areas as an innovative approach to accelerate MRI. CS is expected to achieve higher k-space undersampling by exploiting the underlying sparsity in an appropriate transform domain. MR angiography (MRA) provides high spatial resolution information on arteries; however, a relatively long acquisition time is necessary to cover a wide volume. Reduction of acquisition time by CS for time-of-flight (TOF) MR angiography (Sparse-TOF) is beneficial in clinical examinations; therefore, the clinical validity of Sparse-TOF needs to be investigated...
August 10, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28782410/non-invasive-methods-for-measuring-vascular-changes-in-neurovascular-headaches
#10
Henrik W Schytz, Faisal M Amin, Juliette Selb, David A Boas
Vascular changes during spontaneous headache attacks have been studied over the last 30 years. The interest in cerebral vessels in headache research was initially due to the hypothesis of cerebral vessels as the pain source. Here, we review the knowledge gained by measuring the cerebral vasculature during spontaneous primary headache attacks with the use of single photon emission tomography (SPECT), positron emission tomography (PET), magnetic resonance imaging (MRA) and transcranial Doppler (TCD). Furthermore, the use of near-infrared spectroscopy in headache research is reviewed...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28781924/cerebral-microhemorrhage-a-frequent-magnetic-resonance-imaging-finding-in-pediatric-patients-after-cardiopulmonary-bypass
#11
Paggie P C Kim, Benjamin W Nasman, Erica L Kinne, Udochukwu E Oyoyo, Daniel K Kido, J P Jacobson
OBJECTIVES: This study was undertaken to estimate the incidence and burden of cerebral microhemorrhage (CM) in patients with heart disease who underwent cardiopulmonary bypass (CPB), as detected on susceptibility-weighted imaging (SWI), a magnetic resonance (MR) sequence that is highly sensitive to hemorrhagic products. MATERIALS AND METHODS: With Institutional Review Board waiver of consent, MR imaging (MRI) of a cohort of 86 consecutive pediatric patients with heart failure who underwent heart transplantation evaluation were retrospectively reviewed for CM...
2017: Journal of Clinical Imaging Science
https://www.readbyqxmd.com/read/28777701/a-pet-mr-imaging-approach-for-the-integrated-assessment-of-chemotherapy-induced-brain-heart-and-bone-injuries-in-pediatric-cancer-survivors-a-pilot-study
#12
Ashok J Theruvath, Anat Ilivitzki, Anne Muehe, Johanna Theruvath, Praveen Gulaka, Christine Kim, Sandra Luna-Fineman, Kathleen M Sakamoto, Kristen W Yeom, Phillip Yang, Michael Moseley, Frandics Chan, Heike E Daldrup-Link
Purpose To develop a positron emission tomography (PET)/magnetic resonance (MR) imaging protocol for evaluation of the brain, heart, and joints of pediatric cancer survivors for chemotherapy-induced injuries in one session. Materials and Methods Three teams of experts in neuroimaging, cardiac imaging, and bone imaging were tasked to develop a 20-30-minute PET/MR imaging protocol for detection of chemotherapy-induced tissue injuries of the brain, heart, and bone. In an institutional review board-approved, HIPAA-compliant, prospective study from April to July 2016, 10 pediatric cancer survivors who completed chemotherapy underwent imaging of the brain, heart, and bone with a 3-T PET/MR imager...
August 4, 2017: Radiology
https://www.readbyqxmd.com/read/28776469/relationship-between-haemodynamic-impairment-and-collateral-blood-flow-in-carotid-artery-disease
#13
Nolan S Hartkamp, Esben T Petersen, Michael A Chappell, Thomas W Okell, Maarten Uyttenboogaart, Clark J Zeebregts, Reinoud Ph Bokkers
Collateral blood flow plays a pivotal role in steno-occlusive internal carotid artery (ICA) disease to prevent irreversible ischaemic damage. Our aim was to investigate the effect of carotid artery disease upon cerebral perfusion and cerebrovascular reactivity and whether haemodynamic impairment is influenced at brain tissue level by the existence of primary and/or secondary collateral. Eighty-eight patients with steno-occlusive ICA disease and 29 healthy controls underwent MR examination. The presence of collaterals was determined with time-of-flight, two-dimensional phase contrast MRA and territorial arterial spin labeling (ASL) imaging...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28776269/apparent-brain-temperature-imaging-with-multi-voxel-proton-magnetic-resonance-spectroscopy-compared-with-cerebral-blood-flow-and-metabolism-imaging-on-positron-emission-tomography-in-patients-with-unilateral-chronic-major-cerebral-artery-steno-occlusive-disease
#14
Takamasa Nanba, Hideaki Nishimoto, Yoshichika Yoshioka, Toshiyuki Murakami, Makoto Sasaki, Ikuko Uwano, Shunrou Fujiwara, Kazunori Terasaki, Kuniaki Ogasawara
PURPOSE: The purpose of the present study was to determine whether apparent brain temperature imaging using multi-voxel proton magnetic resonance (MR) spectroscopy correlates with cerebral blood flow (CBF) and metabolism imaging in the deep white matter of patients with unilateral chronic major cerebral artery steno-occlusive disease. METHODS: Apparent brain temperature and CBF and metabolism imaging were measured using proton MR spectroscopy and (15)O-positron emission tomography (PET), respectively, in 35 patients...
August 3, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28774792/macrophage-imaging-of-cerebral-aneurysms-with-ferumoxytol-an-exploratory-study-in-an-animal-model-and-in-patients
#15
Tomohiro Aoki, Makoto Saito, Hirokazu Koseki, Keiichi Tsuji, Atsushi Tsuji, Kiyoshi Murata, Hidetoshi Kasuya, Akio Morita, Shuh Narumiya, Kazuhiko Nozaki
OBJECTIVE: The purpose of this study is to assess the validity and feasibility of macrophage imaging using an ultrasmall superparamagnetic iron oxide nanoparticle, ferumoxytol, in the cerebral aneurysmal wall in an animal model and in humans. MATERIALS AND METHODS: Engulfment of ferumoxytol by primary culture of macrophages and RAW264.7 cells was assessed. Uptake of ferumoxytol was evaluated histologically in a cerebral aneurysmal model in rats. In an exploratory clinical study of magnetic resonance macrophage imaging, 17 unruptured aneurysms in 17 patients were imaged using thin-slice gapless magnetic resonance images of 2D-gradient-recalled echo (2D-GRE) and 3D-T1-fast-spin echo sequences on day 0 and of the same sequences with infusion of ferumoxytol 24 hours after the first imaging...
July 31, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28769870/altered-coupling-between-motion-related-activation-and-resting-state-brain-activity-in-the-ipsilesional-sensorimotor-cortex-after-cerebral-stroke
#16
Jianping Hu, Juan Du, Qiang Xu, Fang Yang, Fanyong Zeng, Xi-Jian Dai, Xiaoxue Liu, Guangming Lu, Zhiqiang Zhang
Functional connectivity maps using resting-state functional magnetic resonance imaging (rs-fMRI) can closely resemble task fMRI activation patterns, suggesting that resting-state brain activity may predict task-evoked activation or behavioral performance. However, this conclusion was mostly drawn upon a healthy population. It remains unclear whether the predictive ability of resting-state brain activity for task-evoked activation would change under different pathological conditions. This study investigated dynamic changes of coupling between patterns of resting-state functional connectivity (RSFC) and motion-related activation in different stages of cerebral stroke...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28762085/the-third-ventricle-roof-an-anatomical-study-using-constructive-interference-in-steady-state-magnetic-resonance-imaging
#17
Satoshi Tsutsumi, Hisato Ishii, Hideo Ono, Yukimasa Yasumoto
PURPOSE: The third ventricle roof in vivo has been infrequently explored. The aim of the present study was to delineate the neurovascular structures relevant to the third ventricle roof using magnetic resonance (MR) imaging. METHODS: A total of 78 patients were enrolled in the study. Following initial examinations with conventional MR sequences, the constructive interference in steady-state (CISS) sequence was performed in coronal sections on 67 patients and in sagittal sections on 11 patients...
July 31, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28760084/optimal-dilution-of-contrast-medium-for-quantitating-parenchymal-blood-volume-using-a-flat-panel-detector
#18
Takumi Kuriyama, Nobuyuki Sakai, Mikiya Beppu, Chiaki Sakai, Hirotoshi Imamura, Iwao Kojima, Katsuhiro Masago, Nobuyuki Katakami
Objective Similar to perfusion studies after acute ischemic stroke, measuring cerebral blood volume (CBV) via C-arm computed tomography before and after therapeutic interventions may help gauge subsequent revascularization. We tested serial dilutions of intra-arterial injectable contrast medium (CM) to determine the optimal CM concentration for quantifying parenchymal blood volume by flat-panel detector imaging (FD-PBV). Methods CM was diluted via saline power injector, instituting time delays for FD-PBV studies...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28752500/negative-impact-of-leukoaraiosis-on-the-incidence-of-brain-metastases-in-patients-with-lung-cancer
#19
Nakamasa Hayashi, Koichi Mitsuya, Yoko Nakasu, Tateaki Naito, Fumiharu Ohka, Toshiaki Takahashi
The embolization of cancer cells to cerebral vessels occurs early in the multi-step metastatic process. We aimed to determine whether the presence of leukoaraiosis (LA) before treatment would predict the development of brain metastases (BM) in patients with lung cancer. Between January 2014 and June 2015, 1007 patients underwent initial (i.e., prior to any chemotherapy) or routine magnetic resonance (MR) imaging of the brain and exhibited no evidence of BM. Of these, 189 underwent repeat MR imaging; 34 of 189 patients (18%) developed new BM, whereas 155 patients did not...
July 27, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28752220/a-patient-with-mitochondrial-disorder-due-to-a-novel-mutation-in-mrps22
#20
Mustafa Kılıç, Kader-Karli Oğuz, Esra Kılıç, Deniz Yüksel, Hüseyin Demirci, Mahmut Şamil Sağıroğlu, Didem Yücel-Yılmaz, Rıza Köksal Özgül
MRPS22 gene defect is a very rare newly discovered mitochondrial disorder. We report a 4-month-old severely affected male infant with MRPS22 mutation. Whole exome sequencing revealed a novel homozygous splicing mutation c.339 + 5 G > A in MRPS22 gene. He has mild dysmorphism, hypotonia, developmental delay but not hypertrophic cardiomyopathy and tubulopathy which differ from other majority of reported patients. Therefore, hypertrophic cardiomyopathy and tubulopathy may not be considered as constant features of MRPS22...
July 27, 2017: Metabolic Brain Disease
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