Che-Sheng Chu, Fu-Chi Yang, Ping-Tao Tseng, Brendon Stubbs, Aarsland Dag, Andre F Carvalho, Trevor Thompson, Yu-Kang Tu, Ta-Chuan Yeh, Dian-Jeng Li, Chia-Kuang Tsai, Tien-Yu Chen, Manabu Ikeda, Chih-Sung Liang, Kuan-Pin Su
INTRODUCTION: We investigated the efficacy and acceptability of pharmacotherapy for dementia with Lewy bodies (DLB) while simultaneously considering the neuropsychiatric symptoms (NPS), cognitive function, motor symptoms, and acceptability. METHODS: Electronic databases were searched from inception through June 5, 2019, for randomized controlled trials (RCTs) and open-label trials (OLTs) in patients with DLB. We performed a pairwise conventional meta-analysis (PWMA) and network meta-analysis (NMA) within a frequentist framework...
September 2021: Archives of Gerontology and Geriatrics