keyword
https://read.qxmd.com/read/38223949/-intracranial-dural-sinus-hypodensity-as-a-sign-of-acute-thrombosis-an-unusually-atypical-radiological-manifestation
#21
E Ruiz-Castellano, J I Cortés-García, A J Láinez-Ramos Bossini
No abstract text is available yet for this article.
January 16, 2024: Revista de Neurologia
https://read.qxmd.com/read/38188061/illusory-motion-and-vection-induced-by-a-printed-static-image-under-flickering-ambient-light-at-rates-up-to-100%C3%A2-hz
#22
JOURNAL ARTICLE
Tomoaki Kozaki, Takeharu Seno, Akiyoshi Kitaoka
Visual motion signals can produce self-motion perception known as vection in observers. Vection can be generated by illusory motions in the form of global expantion in still images as well as by visual motion signals. The perception of vection can be enhanced by flickering images at a rate of 5 Hz. This study examined the illusory motion and vection induced by a printed static image under flickering ambient light at rates up to 100 Hz. The perception of illusory motion and vection were enhanced by flickering ambient lights at 50, 75, and 100 Hz...
2024: I-Perception
https://read.qxmd.com/read/38160013/peptide-l13s-derived-from-the-brn2-pou-domain-reduces-metastasis-in-vivo-and-inhibits-cell-migration-and-invasion-in-vitro
#23
JOURNAL ARTICLE
Maria Carolina Mariano Cesar, Renato Arruda Mortara, Victória Santos Souza, Vitoria Rodrigues Guimaraes Alves, Thaysa Paschoalin, Marco Antonio Soufen, Guilherme Mendes DE Freitas, Fernanda Fernandes Miranda DA Cunha, Dayane Batista Tada, Andrey Senos Dobroff, Denise Costa Arruda
BACKGROUND/AIM: The Brain-Specific Homeobox/POU Domain Protein 2 (BRN2) transcription factor supports melanoma progression by regulating the expression of several genes involved in cell migration and invasion. We hypothesized that a peptide designed based on the POU domain of BRN2 could block the BRN2 transcription activity and, consequently, reduce metastasis. MATERIALS AND METHODS: Cell viability was accessed by Trypan Blue exclusion dye assay and xCelligence platform...
January 2024: Anticancer Research
https://read.qxmd.com/read/38136504/biodiversity-and-constrained-information-dynamics-in-ecosystems-a-framework-for-living-systems
#24
JOURNAL ARTICLE
Kazufumi Hosoda, Shigeto Seno, Rikuto Kamiura, Naomi Murakami, Michio Kondoh
The increase in ecosystem biodiversity can be perceived as one of the universal processes converting energy into information across a wide range of living systems. This study delves into the dynamics of living systems, highlighting the distinction between ex post adaptation, typically associated with natural selection, and its proactive counterpart, ex ante adaptability. Through coalescence experiments using synthetic ecosystems, we (i) quantified ecosystem stability, (ii) identified correlations between some biodiversity indexes and the stability, (iii) proposed a mechanism for increasing biodiversity through moderate inter-ecosystem interactions, and (iv) inferred that the information carrier of ecosystems is species composition, or merged genomic information...
December 5, 2023: Entropy
https://read.qxmd.com/read/38109137/-descripci%C3%A3-n-angiogr%C3%A3-fica-de-los-aspectos-anat%C3%A3-micos-y-cl%C3%A3-nicos-de-la-arteria-interventricular-anterior-en-un-grupo-de-personas-colombianas
#25
JOURNAL ARTICLE
Gustavo Pabón, Valentina Patiño, Guillermo Rivera
UNLABELLED: Introducción. La arteria interventricular anterior se origina en la coronaria izquierda, irriga la cara anterior de los ventrículos, el ápex y el tabique interventricular; es la segunda arteria más relevante del corazón. OBJETIVO: Describir las características anatómicas y clínicas de la arteria interventricular anterior mediante angiografía. Materiales y métodos. Se realizó un estudio descriptivo con 200 reportes angiográficos de personas colombianas; se valoraron el origen, el trayecto y la permeabilidad de la arteria interventricular anterior, así como la dominancia coronaria...
December 1, 2023: Biomédica: Revista del Instituto Nacional de Salud
https://read.qxmd.com/read/38074128/case-report-severe-respiratory-failure-caused-by-licorice
#26
Hiroaki Taniguchi, Takero Terayama, Nobuaki Kiriu, Hiroshi Kato, Soichiro Seno, Yasumasa Sekine, Yoshihiro Tanaka, Tetsuro Kiyozumi
Licorice, one of the most commonly used herbs, can cause hypokalemia, metabolic alkalosis, and apparent mineralocorticoid excess, also known as pseudoaldosteronism. Herein, we present a case of diaphragmatic dysfunction caused by licorice administration. An 80-year-old woman who had been taking dietary supplements and following a restricted diet for approximately 6 months was brought to the emergency department with impaired consciousness. Chronic respiratory acidosis was observed, and hypertension and hypokalemia became more prominent during hospitalization...
2023: Frontiers in Pharmacology
https://read.qxmd.com/read/38032964/transperitoneal-vs-extraperitoneal-radical-cystectomy-a-systematic-review-and-meta-analysis
#27
JOURNAL ARTICLE
Kevin Leonardo, Hendy Mirza, Doddy Hami Seno, Nugroho Purnomo, Andika Afriansyah, Moammar Andar Roemare Siregar
BACKGROUND: One of the most complex surgeries including radical cystectomy (RC) has a high rate of morbidity. The standard approach for the muscle-invasive bladder is conventional transperitoneal radical cystectomy. However, the procedure is associated with significant morbidities like ileus, urinary leak, bleeding, and infection. The aim of this study is to compare the transperitoneal RC approach with the extraperitoneal RC approach in the treatment of bladder cancer patients. The outcomes of this study are Operative time, Estimated Blood Loss, Hospital Stay, Post-Operative Ileus, Infection, and Major Complication (Clavien-Dindo Grade 3-5)...
2023: PloS One
https://read.qxmd.com/read/38013866/bilateral-trauma-case-conferences-an-approach-to-global-surgery-equity-through-a-virtual-education-exchange
#28
JOURNAL ARTICLE
Manisha B Bhatia, Beryl Munda, Philip Okoth, Kyle L Carpenter, Peter Jenkins, Connie H Keung, JoAnna L Hunter-Squires, Seno I Saruni, Clark J Simons
PURPOSE: With increased interest in international surgical experiences, many residency programs have integrated global surgery into their training curricula. For surgical trainees in low- and middle-income countries (LMICs), physical exchange can be costly, and laws in high-income countries (HICs) prevent LMIC trainees from practicing surgery while on visiting rotations. To enrich the educational experience of trainees in both settings, we established a monthly virtual trauma conference between surgery training programs...
2023: Global Surg Educ
https://read.qxmd.com/read/38001886/active-matrix-metalloproteinase-8-ammp-8-versus-total-mmp-8-in-periodontal-and-peri-implant-disease-point-of-care-diagnostics
#29
JOURNAL ARTICLE
Ismo T Räisänen, Nur Rahman Ahmad Seno Aji, Dimitra Sakellari, Andreas Grigoriadis, Iina Rantala, Tommi Pätilä, Pia Heikkilä, Shipra Gupta, Timo Sorsa
Active matrix metalloproteinase-8 (aMMP-8) is a promising biomarker candidate for the modern periodontal and peri-implant disease diagnostics utilizing the chairside/point-of-care oral fluid technologies. These rapid biomarker analysis technologies utilize gingival crevicular fluid (GCF), peri-implant sulcular fluid (PISF), or mouth rinse as the oral fluid matrices that can be collected patient-friendly and non-invasively without causing bacteremia. aMMP-8, but not total or latent proMMP-8, has been shown to be a relevant biomarker to be implemented to the latest 2017 classification system of periodontitis and peri-implantitis...
October 25, 2023: Biomedicines
https://read.qxmd.com/read/37991171/medical-records-as-screening-tools-for-child-death-review-in-japan
#30
JOURNAL ARTICLE
Atsushi Numaguchi, Akira Ishii, Jun Natsume, Shinji Saitoh, Yasuhiro Aoki, Tetsushi Yoshikawa, Ichiro Isobe, Akihisa Okumura, Hiroshi Seno, Yoshiyuki Takahashi
BACKGROUND: Although many child death review (CDR) systems have been developed in Japan, the optimal system is still being identified. The aim of this study is to identify the etiologies of child deaths and to propose a screening method for initiating the CDR process in Japan. METHODS: Clinical medical records (CMRs) in hospitals and autopsy records were surveyed for cases of deaths of children aged less than 15 years between 2014 and 2016 in Aichi Prefecture, Japan...
2023: Pediatrics International: Official Journal of the Japan Pediatric Society
https://read.qxmd.com/read/37989470/synthetic-model-ecosystem-of-12-cryopreservable-microbial-species-allowing-for-a-noninvasive-approach
#31
JOURNAL ARTICLE
Kazufumi Hosoda, Shigeto Seno, Naomi Murakami, Hideo Matsuda, Yutaka Osada, Rikuto Kamiura, Michio Kondoh
Simultaneous understanding of both population and ecosystem dynamics is crucial in an era marked by the degradation of ecosystem services. Experimental ecosystems are a powerful tool for understanding these dynamics; however, they often face technical challenges, typically falling into two categories: "complex but with limited replicability microcosms" and "highly replicable but overly simplistic microcosms." Herein, we present a high-throughput synthetic microcosm system comprising 12 functionally and phylogenetically diverse microbial species...
November 19, 2023: Bio Systems
https://read.qxmd.com/read/37970696/characteristics-of-the-patients-consulted-with-emergency-medicine-physicians-at-a-large-scale-covid-19-vaccination-center-prospective-observational-study
#32
JOURNAL ARTICLE
Soichiro Seno, Takashi Nagata, Kazuo Imai, Takeshi Abe, Shintaro Yamada, Hitomi Tsunashima, Seigo Yamada, Akihito Hagihara, Daizoh Saitoh, Takashi Nishiyama
OBJECTIVE: We aimed to clarify the characteristics of patients consulted by the medical staff with emergency medicine (EM) physicians after vaccination and EM physicians transferred to an outside hospital. DESIGN: The Japanese Self-Defense Force established a large-scale coronavirus disease 2019 (COVID-19) vaccination center. Overall, 1,306,928 citizens received the Moderna vaccine, which targeted the first and second vaccinations between May 24, 2021 and November 30, 2021...
January 2023: American Journal of Disaster Medicine
https://read.qxmd.com/read/37959498/material-extrusion-to-manufacture-carbide-based-advanced-cutting-tools
#33
JOURNAL ARTICLE
Gonçalo Oliveira, Ana Senos, Cristina Fernandes, Daniel Figueiredo, Teresa Vieira
Material extrusion (MEX) allows for the production of advanced cutting tools with new internal cooling systems, which are suitable for new machining equipment. To produce cutting tools via this process, hardmetal and cermet feedstock must be prepared for the extrusion of 3D printing filaments. After shaping the 3D object (green), debinding and sintering must be performed to achieve densification. Defects and microstructural heterogeneities were studied according to the powder material. The present study shows that, although MEX is a viable solution for hardmetals, it needs to produce homogeneous filaments for cermets...
October 27, 2023: Materials
https://read.qxmd.com/read/37951297/single-nucleotide-polymorphisms-of-the-mefv-gene-e148q-are-highly-associated-with-disease-phenotype-in-crohn-s-disease
#34
JOURNAL ARTICLE
Satoshi Yamada, Yusuke Honzawa, Shuji Yamamoto, Minoru Matsuura, Hiroki Kitamoto, Makoto Okabe, Nobuyuki Kakiuchi, Takahiko Toyonaga, Taku Kobayashi, Toshifumi Hibi, Hiroshi Seno, Hiroshi Nakase
BACKGROUND: Single nucleotide polymorphisms (SNPs) of the MEFV gene may modify inflammatory bowel disease (IBD) activity. The prevalence of MEFV gene SNPs in IBD patients and their involvement in IBD pathophysiology remains unclear. METHODS: We analyzed 12 MEFV gene SNPs in peripheral leukocytes of Japanese IBD patients (Crohn's disease [CD]: 69 patients, ulcerative colitis: 32 patients) by polymerase chain reaction using next-generation DNA sequencing and evaluated their prevalence and association with the disease characteristics...
November 10, 2023: Inflammatory Bowel Diseases
https://read.qxmd.com/read/37950802/sporadic-gastric-juvenile-polyposis-with-a-novel-smad4-nonsense-mutation-in-a-mosaic-pattern
#35
JOURNAL ARTICLE
Sho Matsuyama, Akihisa Fukuda, Atsushi Matsumoto, Hidetaka Eguchi, Taro Ueo, Masaya Ohana, Hiroshi Seno
A 50-year-old female was diagnosed with gastric hyperplastic polyps 7 years before and was followed up at another hospital. She was referred to our hospital because of the growth of gastric polyps and progression of anemia. She had no family history of polyposis. The polyps were observed only in the stomach, increased in size and number, and the erythematous edema got worse. Endoscopic mucosal resection (EMR) of the gastric polyp was performed. Pathologically, the gastric polyp was hamartomatous polyp, and the intervening mucosa between polyps showed no atypical structure without inflammation...
November 11, 2023: Clinical Journal of Gastroenterology
https://read.qxmd.com/read/37941619/a-large-growing-occipital-meningocele-with-dandy-walker-syndrome-a-case-report-and-review-of-the-literature
#36
Shirabe Matsumoto, Shinji Iwata, Atsuko Harada, Hikaru Imon, Toshimoto Seno, Hideaki Watanabe, Takeharu Kunieda
BACKGROUND: Dandy-Walker syndrome (DWS) is a well-known developmental anomaly. An occipital meningocele (OMC) is recognized as a malformation that is relatively often associated with DWS, but the association of DWS with OMC has been reported in approximately 40 cases. We present herein a rare clinical course of DWS with OMC, in which the sac was small at birth and became progressively larger. CASE DESCRIPTION: A 5-day-old baby boy was referred to our hospital due to OMC...
2023: Surgical Neurology International
https://read.qxmd.com/read/37935250/tumor-suppressive-activity-of-ahr-in-environmental-arsenic-induced-carcinogenesis
#37
JOURNAL ARTICLE
Ziwei Wang, Yao Fu, Akimasa Seno, Zhuoyue Bi, Aashna S Pawar, Haoyan Ji, Bandar Saeed Almutairy, Yiran Qiu, Wenxuan Zhang, Chitra Thakur, Fei Chen
The aryl hydrocarbon receptor (AHR) is a highly conserved pleiotropic transcription factor that senses environmental pollutants, microbial products, and endogenous ligands. The transcriptional targets of AHR include phase I and phase II detoxification enzymes, as well as numerous signaling molecules that affect a wide spectrum of biological and biochemical processes in a manner of cellular context-dependent. In this review, we systematically assess the latest discoveries of AHR in carcinogenesis with an emphasis on its tumor suppressor-like property that represses the expression of genes in oncogenic signaling pathways...
November 5, 2023: Toxicology and Applied Pharmacology
https://read.qxmd.com/read/37924516/super-enhancer-driven-expression-of-bahcc1-promotes-melanoma-cell-proliferation-and-genome-stability
#38
JOURNAL ARTICLE
Pietro Berico, Maguelone Nogaret, Max Cigrang, Antonin Lallement, Fatemeh Vand-Rajabpour, Amanda Flores-Yanke, Giovanni Gambi, Guillaume Davidson, Leane Seno, Julian Obid, Bujamin H Vokshi, Stephanie Le Gras, Gabrielle Mengus, Tao Ye, Carlos Fernandez Cordero, Mélanie Dalmasso, Emmanuel Compe, Corine Bertolotto, Eva Hernando, Irwin Davidson, Frédéric Coin
Super-enhancers (SEs) are stretches of enhancers ensuring a high level of expression of key genes associated with cell function. The identification of cancer-specific SE-driven genes is a powerful means for the development of innovative therapeutic strategies. Here, we identify a MITF/SOX10/TFIIH-dependent SE promoting the expression of BAHCC1 in a broad panel of melanoma cells. BAHCC1 is highly expressed in metastatic melanoma and is required for tumor engraftment, growth, and dissemination. Integrative genomics analyses reveal that BAHCC1 is a transcriptional regulator controlling expression of E2F/KLF-dependent cell-cycle and DNA-repair genes...
November 2, 2023: Cell Reports
https://read.qxmd.com/read/37901237/immunotherapy-with-sting-and-tlr9-agonists-promotes-synergistic-therapeutic-efficacy-with-suppressed-cancer-associated-fibroblasts-in-colon-carcinoma
#39
JOURNAL ARTICLE
Sare Hajiabadi, Soodeh Alidadi, Zohreh Montakhab Farahi, Mohammad M Ghahramani Seno, Hamidreza Farzin, Alireza Haghparast
The innate immune sensing of nucleic acids using effective immunoadjuvants is critical for increasing protective immune responses against cancer. Stimulators of interferon genes (STING) and toll-like receptor 9 (TLR9) agonists are considered promising candidates in several preclinical tumor models with the potential to be used in clinical settings. However, the effects of such treatment on tumor stroma are currently unknown. In this study, we investigated the immunotherapeutic effects of ADU-S100 as a STING agonist and CpG ODN1826 as a TLR9 agonist in a preclinical model of colon carcinoma...
2023: Frontiers in Immunology
https://read.qxmd.com/read/37877876/transperitoneal-versus-extraperitoneal-approach-for-laparoscopic-and-robot-assisted-radical-prostatectomy-a-systematic-review-and-meta-analysis
#40
JOURNAL ARTICLE
Stefanus Purnomo, Agus Rizal Ardy Hariandy Hamid, Moammar Andar Roemare Siregar, Andika Afriansyah, Hendy Mirza, Doddy Hami Seno, Nugroho Purnomo
To conduct a comparative analysis of outcomes from 2 different surgical approaches, transperitoneal radical prostatectomy (TP-RP) and extraperitoneal radical prostatectomy (EP-RP) in minimally invasive surgery. A comprehensive search was conducted up to September 2022 using 5 online databases, namely PubMed, Cochrane, Scopus, EMBASE, and Science Direct. Studies were screened per the eligibility criteria, and outcomes included operative duration, estimated blood loss (EBL), hospital stay, operative complication, and positive surgical margin...
September 2023: Urol Res Pract
keyword
keyword
4321
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.