John Diaz-Decaro, Evan Myers, Jacek Mucha, Monika Neumann, Witold Lewandowski, Magdalena Kaczanowska, Elvira Schmidt, Andrew Natenshon, Carla Talarico, Philip O Buck
OBJECTIVE: Cytomegalovirus (CMV) infection is typically asymptomatic in healthy individuals; however, certain populations are vulnerable to infection and may develop serious sequelae. CMV infection may also have a broad impact on humanistic outcomes, including patient health status and quality of life (QoL). We conducted a systematic literature review (SLR) to describe the global humanistic burden of CMV and congenital CMV (cCMV) infections across all age groups. METHODS: Medline, Embase, and LILACS were searched to identify studies on humanistic outcomes following CMV infection, including health status/QoL and any outcomes in domains such as auditory, cognitive ability, developmental status, intelligence, language, memory, mental health, motor performance, social communication, speech, and vocabulary...
March 20, 2023: Current Medical Research and Opinion