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https://www.readbyqxmd.com/read/27746792/genome-wide-identification-and-evolution-analysis-of-trehalose-6-phosphate-synthase-gene-family-in-nelumbo-nucifera
#1
Qijiang Jin, Xin Hu, Xin Li, Bei Wang, Yanjie Wang, Hongwei Jiang, Neil Mattson, Yingchun Xu
Trehalose-6-phosphate synthase (TPS) plays a key role in plant carbohydrate metabolism and the perception of carbohydrate availability. In the present work, the publicly available Nelumbo nucifera (lotus) genome sequence database was analyzed which led to identification of nine lotus TPS genes (NnTPS). It was found that at least two introns are included in the coding sequences of NnTPS genes. When the motif compositions were analyzed we found that NnTPS generally shared the similar motifs, implying that they have similar functions...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27680796/c5-preeclampsia-in-twin-pregnancies
#2
Ogochukwu Chantelle Umadia, Dimuthu Vinayagam, Juan Gutierrez Henares, Asma Khalil
AIM: To identify the independent risk factors for PE development in twin pregnancies and explore the associated perinatal outcomes. METHODS: A retrospective cohort study of twin pregnancies was performed at St George's University Hospital, London. Maternal and neonatal data were obtained from the hospital's computerised database. The Chi-square test, Mann-Whitney U test and univariate and multiple-logistic regression analyses were performed. RESULTS: We identified a total of 1250 twin pregnancies who were under the care of SGH from 1999 to 2015...
August 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27676235/a-water-stable-metal-organic-framework-for-highly-sensitive-and-selective-sensing-of-fe-3-ion
#3
Bing-Lei Hou, Dan Tian, Jiang Liu, Long-Zhang Dong, Shun-Li Li, Dong-Sheng Li, Ya-Qian Lan
A new metal-organic framework [Zn5(hfipbb)4(trz)2(H2O)2] (NNU-1) [H2hfipbb = 4,4'-(hexafluoroisopropylidene)bis(benzoic acid), Htrz = 1H-1,2,3-triazole] was assembled by hydrothermal synthesis. Single-crystal X-ray diffraction analysis reveals that NNU-1 displays a twofold interpenetrating three-dimensional (3D) framework with a {4(24)·6(4)}-bcu topology. Interestingly, the 3D framework contains a two-dimensional (2D) layered structure that consists of alternating left- and right-handed double helical chains...
October 17, 2016: Inorganic Chemistry
https://www.readbyqxmd.com/read/27501070/establishment-of-the-relationship-between-fathers-and-premature-infants-in-neonatal-units
#4
Marie-Josée Martel, Isabelle Milette, Linda Bell, Denise St-Cyr Tribble, Antoine Payot
BACKGROUND: Parents and their preterm infants (born between 32-37 weeks of gestation) are often overlooked by the healthcare system. And very little attention is given to the relationship parents develop with their infants in the neonatal unit (NNU). Specifically, very few studies focused on fathers and how they establish a relationship with their infants. However, we know that the father-infant relationship is extremely important for their future social development and more. PURPOSE: This article presents the results of a qualitative study of the establishment of the father-premature infant relationship in an NNU...
August 5, 2016: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/27357123/factors-influencing-the-uptake-of-neonatal-bereavement-support-services-findings-from-two-tertiary-neonatal-centres-in-the-uk
#5
Jayanta Banerjee, Charanjit Kaur, Sridhar Ramaiah, Rahul Roy, Narendra Aladangady
BACKGROUND: Research on perinatal bereavement services is limited. The aim of the study was to compare the uptake of bereavement support services between two tertiary neonatal units (NNU), and to investigate influencing factors. METHOD: The medical and bereavement records of all neonatal deaths were studied from January 2006 to December 2011. Data collected included parent and baby characteristics, mode of death, consent for autopsy and bereavement follow-up. The categorical data were compared by chi-square or Fisher's exact test and continuous data by Wilcoxon signed-rank test; a multivariable regression analysis was performed using STATA 12...
2016: BMC Palliative Care
https://www.readbyqxmd.com/read/27348583/the-feasibility-of-using-premiestart-a-mother-premature-infant-interaction-program-on-a-neonatal-unit-in-england
#6
Alexandra L Dibley, Tracy Rydin-Orwin, Jacqui Stedmon, Rudi Dallos
This article explores the feasibility of running "PremieStart," a nine-individual-session maternal-premature infant interaction program, within a neonatal unit (NNU) in England. Four mothers of premature infants completed seven sessions on the NNU and two at home. Mothers and NNU staff provided feedback on PremieStart. Measures of maternal-infant relationship, maternal well-being, and maternal reflective functioning were completed before and after intervention. Thematic analysis of mothers' feedback highlighted the emotional, but cathartic, experience of engaging with PremieStart...
July 2016: Infant Mental Health Journal
https://www.readbyqxmd.com/read/26597751/association-between-maternal-haemoglobin-at-27-29weeks-gestation-and-intrauterine-growth-restriction
#7
Mark Cordina, Sadia Bhatti, Marianna Fernandez, Argyro Syngelaki, Kypros H Nicolaides, Nikos A Kametas
OBJECTIVE: To examine the relationship between maternal haemoglobin concentration (Hb) at 27-29weeks' gestation and fetal growth restriction (FGR). DESIGN: This was a retrospective, case control study. SETTING: A University hospital in London, UK. POPULATION: Pregnant women attending for routine antenatal care at 27-29weeks of pregnancy. METHODS: Maternal Hb, measured routinely at 27-29weeks in pregnancies complicated by FGR (n=491) was compared to normal controls (n=491)...
October 2015: Pregnancy Hypertension
https://www.readbyqxmd.com/read/26230688/distribution-of-adat-dependent-codons-in-the-human-transcriptome
#8
Àlbert Rafels-Ybern, Camille Stephan-Otto Attolini, Lluís Ribas de Pouplana
Nucleotide modifications in the anticodons of transfer RNAs (tRNA) play a central role in translation efficiency, fidelity, and regulation of translation, but, for most of these modifications, the details of their function remain unknown. The heterodimeric adenosine deaminases acting on tRNAs (ADAT2-ADAT3, or ADAT) are enzymes present in eukaryotes that convert adenine (A) to inosine (I) in the first anticodon base (position 34) by hydrolytic deamination. To explore the influence of ADAT activity on mammalian translation, we have characterized the human transcriptome and proteome in terms of frequency and distribution of ADAT-related codons...
2015: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/26224608/biophysical-and-biochemical-markers-at-35-37-weeks-gestation-in-the-prediction-of-adverse-perinatal-outcome
#9
N Valiño, G Giunta, D M Gallo, R Akolekar, K H Nicolaides
OBJECTIVE: To investigate the potential value of biophysical and biochemical markers at 35-37 weeks' gestation in the prediction of adverse perinatal outcome. METHODS: This was a screening study in 3953 singleton pregnancies at 35-37 weeks' gestation. Estimated fetal weight (EFW), uterine artery pulsatility index (UtA-PI), umbilical artery (UA)-PI, fetal middle cerebral artery (MCA)-PI, mean arterial pressure (MAP), serum placental growth factor (PlGF) and soluble fms-like tyrosine kinase-1 (sFlt-1) were measured...
February 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/26094952/biophysical-and-biochemical-markers-at-30-34-weeks-gestation-in-the-prediction-of-adverse-perinatal-outcome
#10
N Valiño, G Giunta, D M Gallo, R Akolekar, K H Nicolaides
OBJECTIVE: To investigate the potential value of biophysical and biochemical markers at 30-34 weeks' gestation in the prediction of adverse perinatal outcome. METHODS: This was a screening study in 8268 singleton pregnancies at 30-34 weeks' gestation. Estimated fetal weight (EFW), uterine artery (UtA) pulsatility index (PI), umbilical artery (UA) PI, fetal middle cerebral artery (MCA) PI, mean arterial pressure (MAP), serum placental growth factor (PlGF) and soluble fms-like tyrosine kinase-1 (sFlt-1) were measured...
February 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/25834169/neonatal-outcomes-and-delivery-of-care-for-infants-born-late-preterm-or-moderately-preterm-a-prospective-population-based-study
#11
Elaine M Boyle, Samantha Johnson, Bradley Manktelow, Sarah E Seaton, Elizabeth S Draper, Lucy K Smith, Jon Dorling, Neil Marlow, Stavros Petrou, David J Field
OBJECTIVE: To describe neonatal outcomes and explore variation in delivery of care for infants born late (34-36  weeks) and moderately (32-33 weeks) preterm (LMPT). DESIGN/SETTING: Prospective population-based study comprising births in four major maternity centres, one midwifery-led unit and at home between September 2009 and December 2010. Data were obtained from maternal and neonatal records. PARTICIPANTS: All LMPT infants were eligible...
November 2015: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/25779696/umbilical-and-fetal-middle-cerebral-artery-doppler-at-35-37-weeks-gestation-in-the-prediction-of-adverse-perinatal-outcome
#12
R Akolekar, A Syngelaki, D M Gallo, L C Poon, K H Nicolaides
OBJECTIVE: To investigate the potential value of cerebroplacental ratio (CPR) at 36 weeks' gestation in the prediction of adverse perinatal outcome. METHODS: This was a screening study in 6178 singleton pregnancies at 35-37 weeks' gestation. Umbilical artery (UA) and fetal middle cerebral artery (MCA) pulsatility index (PI) were measured and the values were converted to multiples of the median (MoM) after adjustment from variables in maternal characteristics and medical history that affect the measurements...
July 2015: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/25684172/umbilical-and-fetal-middle-cerebral-artery-doppler-at-30-34-weeks-gestation-in-the-prediction-of-adverse-perinatal-outcome
#13
S Bakalis, R Akolekar, D M Gallo, L C Poon, K H Nicolaides
OBJECTIVE: To investigate the potential value of cerebroplacental ratio (CPR) at 30-34 weeks' gestation in the prediction of adverse perinatal outcome. METHODS: This was a screening study in 30 780 singleton pregnancies at 30-34 weeks' gestation. Umbilical artery (UA) and fetal middle cerebral artery (MCA) pulsatility index (PI) were measured and the values were converted to multiples of the median (MoM) after adjustment from variables in maternal characteristics and medical history that affect the measurements...
April 2015: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/25446667/is-fetal-cerebroplacental-ratio-an-independent-predictor-of-intrapartum-fetal-compromise-and-neonatal-unit-admission
#14
Asma A Khalil, José Morales-Rosello, Maddalena Morlando, Hasina Hannan, Amar Bhide, Aris Papageorghiou, Basky Thilaganathan
OBJECTIVE: We sought to evaluate the association between fetal cerebroplacental ratio (CPR) and intrapartum fetal compromise and admission to the neonatal unit (NNU) in term pregnancies. STUDY DESIGN: This was a retrospective cohort study in a single tertiary referral center over a 14-year period from 2000 through 2013. The umbilical artery pulsatility index, middle cerebral artery pulsatility index, and CPR were recorded within 2 weeks of delivery. The birthweight (BW) values were converted into centiles and Doppler parameters converted into multiples of median (MoM), adjusting for gestational age using reference ranges...
July 2015: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/25146223/survey-of-neonatal-unit-outbreaks-in-north-london-identifying-causes-and-risk-factors
#15
K Williams, S Hopkins, D Turbitt, C Seng, B Cookson, B C Patel, R J Manuel
BACKGROUND: This survey was undertaken after a number of neonatal unit (NNU) outbreaks were reported to the North London health protection teams (HPTs). AIM: To determine the diversity of the outbreaks, ascertain potential sources and contributing factors, and identify the investigative procedures followed and control measures implemented. METHODS: Using a structured questionnaire, information from the HPT database was collected for all NNU outbreaks reported between January 2010 and February 2011...
November 2014: Journal of Hospital Infection
https://www.readbyqxmd.com/read/24797124/biomarkers-to-decide-red-blood-cell-transfusion-in-newborn-infants
#16
REVIEW
Jayanta Banerjee, Narendra Aladangady
Almost 90% of extremely low birthweight infants receive red blood cell (RBC) transfusion during their stay in the neonatal unit (NNU). Currently most NNUs use a combination of clinical signs and laboratory findings such as hemoglobin (Hb), hematocrit (Hct), and cardiorespiratory or ventilation status to decide the need for RBC transfusion. Various other laboratory (lactate, reticulocyte count, RBC volume) and bedside measurements (near infrared spectroscopy and Doppler ultrasound scan) have been investigated to identify a suitable trigger for RBC transfusion in newborn infants...
October 2014: Transfusion
https://www.readbyqxmd.com/read/24646619/the-impact-of-routine-predischarge-pulse-oximetry-screening-in-a-regional-neonatal-unit
#17
Anju Singh, Shree Vishna Rasiah, Andrew K Ewer
OBJECTIVES: (i) To evaluate the impact of routine early pulse oximetry screening on the rate of unexpected neonatal unit (NNU) admissions and the need for echocardiography. (ii) To review the outcomes of babies admitted as a result of a positive pulse oximetry screening test. DESIGN: Retrospective review over a 40-month period. SETTING: Level 3 NNU. PATIENTS: All babies admitted as a result of positive pulse oximetry screening...
July 2014: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/24372811/risk-factors-for-mortality-among-human-immunodeficiency-virus-exposed-and-unexposed-infants-admitted-to-a-neonatal-intensive-care-unit-in-botswana
#18
Rebecca M Zash, Olubunmi Ajose-Popoola, Ketil Stordal, Sajini Souda, Anthony Ogwu, Scott Dryden-Peterson, Kathleen Powis, Shahin Lockman, Joe Makhema, Max Essex, Roger L Shapiro
AIM: Newborns admitted to neonatal units (NNUs) in resource-limited settings face a high risk of mortality, but the epidemiology of these deaths is poorly understood. We describe risk factors for NNU mortality in an area with high prevalence of human immunodeficiency virus (HIV). METHODS: We performed a prospective cohort study of infants admitted to the NNU at a public referral hospital in Gaborone, Botswana. The primary outcome was neonatal death, defined as death within 28 days of a live delivery...
March 2014: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/24111635/cervical-il-6-and-pigfbp-1-and-the-prediction-of-neonatal-outcome-in-symptomatic-preterm-labour
#19
Maia Brik, Marta Aguar, Ana Valiente, Alfredo Perales
OBJECTIVE: To evaluate the use of cervical Interleukin 6 (IL-6) and phosphorylated Insulin Growth Binding Protein 1 (pIGFBP1) in the prediction of adverse neonatal outcome. METHODS: Prospective observational study including women between 24 and 34 weeks of gestation. One hundred and twelve cervical samples for IL-6 and pIFBP1 were taken. Neonatal outcome variables were birth weight, Apgar scores at 1st/5th minute, gestational age at delivery, admission to neonatal unit (NNU) and to neonatal intensive care unit (NICU), composite neonatal morbidity (NCM) and neonatal mortality...
August 2014: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/23964826/pediatric-pressure-injuries-does-modifying-a-tool-alter-the-risk-assessment-outcome
#20
Paul Leonard, Astrid Hill, Kylie Moon, Sally Lima
The aim of this study was to determine whether assessing patient risk of developing pressure injuries in Pediatric Intensive Care (PICU) and Neonatal Units (NNU) using a modification of the Glamorgan Scale (mGS) would alter the risk identification when compared to the Glamorgan Scale (GS). Prospective data were collected from a convenience sample of patients admitted to PICU or NNU during a 2-month period. The patients' pressure injury risk score using both instruments was collected by observing patients, reviewing patient records, and clarifying information with bedside nurses...
December 2013: Issues in Comprehensive Pediatric Nursing
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