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Peter Olupot-Olupot, Emma I E Eregu, Ketty Naizuli, Julie Ikiror, Linda Acom, Kathy Burgoine
BACKGROUND: Congenital malaria is the direct infection of an infant with malaria parasites from their mother prior to or during birth. Neonatal malaria is due to an infective mosquito bite after birth. Neonatal and congenital malaria (NCM) are potentially life-threatening conditions that are believed to occur at relatively low rates in malaria endemic regions. However, recent reports suggest that the number of NCM cases is increasing, and its epidemiology remains poorly described. NCM can mimic other neonatal conditions and because it is thought to be rare, blood film examinations for malaria are not always routinely performed...
April 20, 2018: Malaria Journal
Ya-Qian Lan, Xiao-Li Wang, Long-Zhang Dong, Man Qiao, Yu-Jia Tang, Jiang Liu, Yafei Li, Shun-Li Li, Jia-Xin Su
Abundant bimetallic electrocatalysts for oxygen evolution reaction (OER) have been developed recently due to the superior performance. However, the in-depth understanding of the performance improvement in bimetallic electrocatalysts remains a huge challenge. Here, we designed and synthesized a series of stable metal-organic frameworks (MOFs: NNU-21~24) based on trinuclear metal carboxylate clusters and tridentate carboxylate ligands. The precise structures and excellent stability of MOFs contribute to the investigation of their OER performance...
April 16, 2018: Angewandte Chemie
Xue-Li Cao, Shuai-Lei Xie, Shun-Li Li, Long-Zhang Dong, Jiang Liu, Xi-Xi Liu, Wen-Bin Wang, Zhong-Min Su, Wei Guan, Ya-Qian Lan
Three new proton conductors with simple structures based on isolated olyoxometalate anions as well as protonated imidazole and benzimidazole, namely, NNU-6-8, have been successfully prepared by hydrothermal reaction. We could control the number of proton sources by selecting different types and changing the charges of POM anions. The single crystal sample of NNU-6 along a-axis shows a highest proton conductivity of 1.91×10-2  S cm-1 , which is two and three orders of magnitude higher than that of 2.42×10-4 and 8...
February 16, 2018: Chemistry: a European Journal
Victoria Payne, Mike Hall, Jacqui Prieto, Mark Johnson
BACKGROUND: Central line-associated bloodstream infections (CLABSIs) are associated with increased mortality, prolonged hospitalisation and increased healthcare costs. Care bundles have reduced CLABSIs in adult intensive care units (ICUs) but replication in paediatric ICUs has had inconsistent outcomes. A systematic review was performed to assess the evidence for the efficacy of care bundles in reducing CLABSIs in the neonatal unit (NNU). METHODS: MEDLINE, CINAHL and EMBASE were searched from January 2010 up to January 2017...
November 25, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
S Eldirdiri, J Lee, A Jack, A Wright, A Findlay, G Phillips
BACKGROUND: This report describes an outbreak of gentamicin-resistant, meticillin-resistant Staphylococcus aureus (GR MSSA) which occurred on a 21-bed neonatal unit (NNU) in Ninewells Hospital, Dundee, UK. METHODS: An outbreak investigation was triggered by two new GR MSSA isolates from babies admitted directly to the NNU who had acquired this organism during their stay. Data on MSSA cases and antibiograms of patient isolates were flagged as an alert, and microbiology records were trawled to detect previous cases...
April 2018: Journal of Hospital Infection
Suma Uday, Ardita Kongjonaj, Magda Aguiar, Ted Tulchinsky, Wolfgang Högler
BACKGROUND: Nutritional rickets is a growing global public health concern despite existing prevention programmes and health policies. We aimed to compare infant and childhood vitamin D supplementation policies, implementation strategies and practices across Europe and explore factors influencing adherence. METHODS: European Society for Paediatric Endocrinology Bone and Growth Plate Working Group members and other specialists completed a questionnaire on country-specific vitamin D supplementation policy and child health care programmes, socioeconomic factors, policy implementation strategies and adherence...
November 2017: Endocrine Connections
Susan Kerr, Caroline King, Rhona Hogg, Kerri McPherson, Janet Hanley, Maggie Brierton, Sean Ainsworth
BACKGROUND: Complications during pregnancy, childbirth and/or the postnatal period may result in the admission of a baby to a neonatal unit (NNU). While the survival and long-term prospects of high-risk infants are enhanced by admission, the enforced separation of the parent and child may have psychological consequences for both. There is a need to develop and evaluate interventions to help parents 'feel closer' to their infants in circumstances where they are physically separated from them...
July 11, 2017: BMC Pediatrics
M Veglia, A Cavallaro, A Papageorghiou, R Black, L Impey
OBJECTIVES: Although no clear evidence exists, many international guidelines advocate early term delivery of small for gestational age (SGA) fetuses. The aim of this study was to determine whether a protocol that included monitoring SGA fetuses beyond 37 weeks affected perinatal and maternal outcomes. METHODS: The impact of the introduction in 2014 of a protocol for management of SGA, which included risk stratification with surveillance and expectant management after 37 weeks for lower risk babies (Group 2), was compared with the previous strategy, which recommended delivery at around 37 weeks (Group 1)...
June 10, 2017: Ultrasound in Obstetrics & Gynecology
Qijiang Jin, Yingchun Xu, Neil Mattson, Xin Li, Bei Wang, Xiao Zhang, Hongwei Jiang, Xiaojing Liu, Yanjie Wang, Dongrui Yao
MicroRNAs (miRNAs) are endogenous non-coding RNAs with important regulatory functions in plant development and stress responses. However, their population abundance in lotus (Nelumbo nucifera Gaertn) has so far been poorly described, particularly in response to stresses. In this work, submergence-related miRNAs and their target genes were systematically identified, compared, and validated at the transcriptome-wide level using high-throughput sequencing data of small RNA, Mrna, and the degradome. A total of 128 known and 20 novel miRNAs were differentially expressed upon submergence...
2017: Frontiers in Plant Science
(no author information available yet)
Members of the union National Nurses United (NNU) gathered in 40 US cities (including New York, pictured) on the eve of president Donald Trump's inauguration, demanding that access to health care be safeguarded.
January 25, 2017: Nursing Standard
Silvia Gullino, Anthony Kaiser, Hammad Khan, Aisling Phillips, Alice Elwin, A D Edwards
AIM: Studies have explored how mothers and premature babies make the transition from a neonatal unit (NNU) to home, but little is known about how mothers cope with urban life with a vulnerable baby. This controlled trial investigated how first-time mothers with singleton preterm babies handled that experience in the first few months after discharge from a NNU, compared to the first-time mothers of healthy, singleton term-born infants. METHODS: This parent-led, qualitative study was carried out in London, UK, from 2013 to 2015 and used diaries and walking interviews with researchers...
December 17, 2016: Acta Paediatrica
Qijiang Jin, Xin Hu, Xin Li, Bei Wang, Yanjie Wang, Hongwei Jiang, Neil Mattson, Yingchun Xu
Trehalose-6-phosphate synthase (TPS) plays a key role in plant carbohydrate metabolism and the perception of carbohydrate availability. In the present work, the publicly available Nelumbo nucifera (lotus) genome sequence database was analyzed which led to identification of nine lotus TPS genes (NnTPS). It was found that at least two introns are included in the coding sequences of NnTPS genes. When the motif compositions were analyzed we found that NnTPS generally shared the similar motifs, implying that they have similar functions...
2016: Frontiers in Plant Science
Ogochukwu Chantelle Umadia, Dimuthu Vinayagam, Juan Gutierrez Henares, Asma Khalil
AIM: To identify the independent risk factors for PE development in twin pregnancies and explore the associated perinatal outcomes. METHODS: A retrospective cohort study of twin pregnancies was performed at St George's University Hospital, London. Maternal and neonatal data were obtained from the hospital's computerised database. The Chi-square test, Mann-Whitney U test and univariate and multiple-logistic regression analyses were performed. RESULTS: We identified a total of 1250 twin pregnancies who were under the care of SGH from 1999 to 2015...
August 2016: Journal of Maternal-fetal & Neonatal Medicine
Bing-Lei Hou, Dan Tian, Jiang Liu, Long-Zhang Dong, Shun-Li Li, Dong-Sheng Li, Ya-Qian Lan
A new metal-organic framework [Zn5 (hfipbb)4 (trz)2 (H2 O)2 ] (NNU-1) [H2 hfipbb = 4,4'-(hexafluoroisopropylidene)bis(benzoic acid), Htrz = 1H-1,2,3-triazole] was assembled by hydrothermal synthesis. Single-crystal X-ray diffraction analysis reveals that NNU-1 displays a twofold interpenetrating three-dimensional (3D) framework with a {424 ·64 }-bcu topology. Interestingly, the 3D framework contains a two-dimensional (2D) layered structure that consists of alternating left- and right-handed double helical chains...
October 17, 2016: Inorganic Chemistry
Marie-Josée Martel, Isabelle Milette, Linda Bell, Denise St-Cyr Tribble, Antoine Payot
BACKGROUND: Parents and their preterm infants (born between 32-37 weeks of gestation) are often overlooked by the healthcare system. And very little attention is given to the relationship parents develop with their infants in the neonatal unit (NNU). Specifically, very few studies focused on fathers and how they establish a relationship with their infants. However, we know that the father-infant relationship is extremely important for their future social development and more. PURPOSE: This article presents the results of a qualitative study of the establishment of the father-premature infant relationship in an NNU...
August 5, 2016: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
Jayanta Banerjee, Charanjit Kaur, Sridhar Ramaiah, Rahul Roy, Narendra Aladangady
BACKGROUND: Research on perinatal bereavement services is limited. The aim of the study was to compare the uptake of bereavement support services between two tertiary neonatal units (NNU), and to investigate influencing factors. METHOD: The medical and bereavement records of all neonatal deaths were studied from January 2006 to December 2011. Data collected included parent and baby characteristics, mode of death, consent for autopsy and bereavement follow-up. The categorical data were compared by chi-square or Fisher's exact test and continuous data by Wilcoxon signed-rank test; a multivariable regression analysis was performed using STATA 12...
June 29, 2016: BMC Palliative Care
Alexandra L Dibley, Tracy Rydin-Orwin, Jacqui Stedmon, Rudi Dallos
This article explores the feasibility of running "PremieStart," a nine-individual-session maternal-premature infant interaction program, within a neonatal unit (NNU) in England. Four mothers of premature infants completed seven sessions on the NNU and two at home. Mothers and NNU staff provided feedback on PremieStart. Measures of maternal-infant relationship, maternal well-being, and maternal reflective functioning were completed before and after intervention. Thematic analysis of mothers' feedback highlighted the emotional, but cathartic, experience of engaging with PremieStart...
July 2016: Infant Mental Health Journal
Mark Cordina, Sadia Bhatti, Marianna Fernandez, Argyro Syngelaki, Kypros H Nicolaides, Nikos A Kametas
OBJECTIVE: To examine the relationship between maternal haemoglobin concentration (Hb) at 27-29weeks' gestation and fetal growth restriction (FGR). DESIGN: This was a retrospective, case control study. SETTING: A University hospital in London, UK. POPULATION: Pregnant women attending for routine antenatal care at 27-29weeks of pregnancy. METHODS: Maternal Hb, measured routinely at 27-29weeks in pregnancies complicated by FGR (n=491) was compared to normal controls (n=491)...
October 2015: Pregnancy Hypertension
Àlbert Rafels-Ybern, Camille Stephan-Otto Attolini, Lluís Ribas de Pouplana
Nucleotide modifications in the anticodons of transfer RNAs (tRNA) play a central role in translation efficiency, fidelity, and regulation of translation, but, for most of these modifications, the details of their function remain unknown. The heterodimeric adenosine deaminases acting on tRNAs (ADAT2-ADAT3, or ADAT) are enzymes present in eukaryotes that convert adenine (A) to inosine (I) in the first anticodon base (position 34) by hydrolytic deamination. To explore the influence of ADAT activity on mammalian translation, we have characterized the human transcriptome and proteome in terms of frequency and distribution of ADAT-related codons...
July 29, 2015: International Journal of Molecular Sciences
N Valiño, G Giunta, D M Gallo, R Akolekar, K H Nicolaides
OBJECTIVE: To investigate the potential value of biophysical and biochemical markers at 35-37 weeks' gestation in the prediction of adverse perinatal outcome. METHODS: This was a screening study in 3953 singleton pregnancies at 35-37 weeks' gestation. Estimated fetal weight (EFW), uterine artery pulsatility index (UtA-PI), umbilical artery (UA)-PI, fetal middle cerebral artery (MCA)-PI, mean arterial pressure (MAP), serum placental growth factor (PlGF) and soluble fms-like tyrosine kinase-1 (sFlt-1) were measured...
February 2016: Ultrasound in Obstetrics & Gynecology
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