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Paediatric intensive care

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https://www.readbyqxmd.com/read/28442215/-neopterin-levels-and-systemic-inflammatory-response-syndrome-in-pediatric-critically-ill-patients
#1
Raquel Gil-Gómez, Javier Blasco-Alonso, Pilar Sánchez-Yáñez, Vanessa Rosa-Camacho, Guillermo Milano Manso
INTRODUCTION: Neopterin and biopterin are sub-products of redox reactions, which act as cofactors of enzymes responsible for nitric oxide production. The hypothesis is presented that plasma neopterin and biopterin evolve differently during the first days in a critically ill child. METHODS: A single-centre prospective observational study was conducted on patients 7 days to 14 years admitted to our Paediatric Intensive Care Unit (PICU) and that met Systemic inflammatory response syndrome (SIRS) criteria...
April 22, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/28436613/paediatric-acute-care-highlights-from-the-paediatric-acute-care-advanced-paediatric-life-support-conference-adelaide-2016
#2
Stephen Ss Teo, Jacquie Schutz, Jane Stanford, Arjun Rao
The Paediatric Acute Care Conference (PACC) is an annual conference organised by Advanced Paediatric Life Support Australia to advance paediatric acute care topics for clinicians in pre-hospital medicine, EDs, acute paediatrics, intensive care and anaesthesia. The PACC 2016 was held at Glenelg, Adelaide, Australia. We provide a summary of some of the presentations.
April 24, 2017: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/28431900/-quality-of-initial-trauma-care-in-paediatrics
#3
Vicente Ibáñez Pradas, Rut Pérez Montejano
INTRODUCTION: Trauma care in Spain is not provided in specific centres, which means that health professionals have limited contact to trauma patients. After the setting up of a training program in paediatric trauma, the aim of this study was to evaluate the quality of the initial care provided to these patients before they were admitted to the paediatric intensive care unit (PICU) of a third level hospital (trauma centre), as an indirect measurement of the increase in the number of health professionals trained in trauma...
April 18, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/28428012/-retrospective-study-of-children-referred-from-paediatric-intensive-care-to-palliative-care-why-and-for-what
#4
Alberto García-Salido, Paula Santos-Herranz, Verónica Puertas-Martín, María Ángeles García-Teresa, Ricardo Martino-Alba, Ana Serrano-González
INTRODUCTION: The creation of paediatric palliative care units (PPCU) could optimise the management of children with palliative focus after admission to a paediatric intensive care unit (PICU). This study describes the clinical and epidemiological characteristics of children referred from PICU to the UCPP of the Autonomous Community of Madrid (CAM). The overall treatment, relapses, re-admissions, and deaths, if occurred, are described. PATIENTS AND METHOD: A retrospective review was performed using the medical records from children transferred from the CAM paediatric intensive care units to the paediatric palliative care unit (1 March 2008-31 January 2015)...
April 17, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/28421191/prospective-multicentre-study-on-the-epidemiology-and-current-therapeutic-management-of-severe-bronchiolitis-in-spain
#5
Jose C Flores-González, Juan Mayordomo-Colunga, Iolanda Jordan, Alicia Miras-Veiga, Cristina Montero-Valladares, Marta Olmedilla-Jodar, Andrés J Alcaraz-Romero, Miren Eizmendi-Bereciartua, Francisco Fernández-Carrión, Carmen Santiago-Gutierrez, Esther Aleo-Luján, Sonia Pérez-Quesada, Cristina Yun-Castilla, Carmen Martín, Álvaro Navarro-Mingorance, Concha Goñi-Orayen
Objective. To determine the epidemiology and therapeutic management of patients with severe acute bronchiolitis (AB) admitted to paediatric intensive care units (PICUs) in Spain. Design. Descriptive, prospective, multicentre study. Setting. Sixteen Spanish PICUs. Patients. Patients with severe AB who required admission to any of the participating PICUs over 1 year. Interventions. Both epidemiological variables and medical treatment received were recorded. Results. A total of 262 patients were recruited; 143 were male (54...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28417303/paediatric-in-patient-prescribing-errors-in-malaysia-a-cross-sectional-multicentre-study
#6
Teik Beng Khoo, Jing Wen Tan, Hoong Phak Ng, Chong Ming Choo, Intan Nor Chahaya Bt Abdul Shukor, Siao Hean Teh
Background There is a lack of large comprehensive studies in developing countries on paediatric in-patient prescribing errors in different settings. Objectives To determine the characteristics of in-patient prescribing errors among paediatric patients. Setting General paediatric wards, neonatal intensive care units and paediatric intensive care units in government hospitals in Malaysia. Methods This is a cross-sectional multicentre study involving 17 participating hospitals. Drug charts were reviewed in each ward to identify the prescribing errors...
April 17, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28416561/requirements-for-and-current-provision-of-rehabilitation-services-for-children-after-severe-acquired-brain-injury-in-the-uk-a-population-based-study
#7
Louise Hayes, Simon Shaw, Mark S Pearce, Rob J Forsyth
OBJECTIVES: Survival with brain injury is an outcome of severe illness that may be becoming more common. Provision for children in this situation has received little attention. We sought to estimate rates of severe paediatric acquired brain injury (ABI) requiring rehabilitation and to describe current provision of services for these children in the UK. METHODS: This study conducted an analysis of Hospital Episode Statistics data between April 2003 and March 2012, supplemented by a UK provider survey completed in 2015...
April 17, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28412958/supporting-parents-in-taking-care-of-their-infants-admitted-to-a-neonatal-intensive-care-unit-a-prospective-cohort-pilot-study
#8
Giuseppe De Bernardo, Maria Svelto, Maurizio Giordano, Desiree Sordino, Marina Riccitelli
BACKGROUND: Family-Centred Care (FCC) is recognized as an important component of all paediatric care, including neonatal care, although practical clinical guidelines to support this care model are still needed in Italy. The characteristics and services for families in Italian NICUs show a lack of organization and participation. METHODS: The first aim was to compare satisfaction and stress levels in two groups of parents: an FCC group and a non-FCC group (NFCC). The second aim was to evaluate body weight gain in the newborns enrolled...
April 17, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/28408466/-best-interests-in-paediatric-intensive-care-an-empirical-ethics-study
#9
Giles Birchley, Rachael Gooberman-Hill, Zuzana Deans, James Fraser, Richard Huxtable
OBJECTIVE: In English paediatric practice, English law requires that parents and clinicians agree the 'best interests' of children and, if this is not possible, that the courts decide. Court intervention is rare and the concept of best interests is ambiguous. We report qualitative research exploring how the best interests standard operates in practice, particularly with decisions related to planned non-treatment. We discuss results in the light of accounts of best interests in the medical ethics literature...
April 13, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28403414/a-national-survey-of-videolaryngoscopy-in-the-united-kingdom
#10
T M Cook, F E Kelly
Background.: There are increasing numbers of videolaryngoscopes marketed and increasing interest in the technology. The Difficult Airway Society's 2015 guidelines recommend that videolaryngoscopes should be immediately available at all times and that all anaesthetists should be trained and skilled in their use. Methods.: An electronic survey was sent to all UK National Health Service hospitals to examine availability, use, and attitudes to videolaryngoscopy, and closed in January 2014...
April 1, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28398658/challenges-of-paediatric-organ-donation
#11
REVIEW
Ben Gelbart
Paediatric organ donation represents a small fraction of overall organ donation in Australia and New Zealand and indeed world-wide. Many factors contribute to low donation rates including low paediatric intensive care mortality, consent rates and medical suitability relating to disease, age and size. In the past decade, the re-emergence of donation after circulatory death has changed the landscape for the paediatric population. This article reviews the current status and challenges of organ donation for the paediatric population...
April 11, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28382621/spironolactone-effect-on-potassium-supplementation-in-paediatric-cardiac-intensive-care-patients
#12
B S Moffett, T E Haworth, Y Wang, N Afonso, P A Checchia
WHAT IS KNOWN: Spironolactone is used in paediatric patients with heart disease, yet few data are available regarding the impact on potassium supplementation. OBJECTIVE: We sought to determine the effect of spironolactone on potassium supplementation in paediatric cardiac intensive care patients. METHODS: A retrospective, propensity matched cohort study was designed. Patients were included in the study if they received furosemide therapy in the cardiac intensive care unit at our institution...
April 5, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/28380408/haemodynamic-changes-with-paracetamol-in-critically-ill-children
#13
Samiran Ray, Thomas Brick, Sainath Raman, Paul J Birrell, Nigel J Klein, Mark J Peters
PURPOSE: Paracetamol has been associated with a reduction in blood pressure, especially in febrile, critically-ill adults. We hypothesised that blood pressure would fall following administration of paracetamol in critically-ill children and this effect would be greater during fever and among children with a high body surface area to weight ratio. METHODS: A 12-month prospective observational study of children (0-16years) admitted to paediatric intensive care, who underwent pulse contour analysis and received paracetamol concurrently...
March 30, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28366695/-streptococcus-pyogenes-infection-in-paediatrics-from-pharyngotonsillitis-to-invasive-infections
#14
David Espadas Maciá, Eva María Flor Macián, Rafael Borrás, Sandrine Poujois Gisbert, Juan Ignacio Muñoz Bonet
BACKGROUND: Streptococcus pyogenes or Group A Streptococci (GAS) cause many infections in infancy. Changes in its epidemiology have been described in recent years, including an increase in invasive infections (iGAS). METHODS: A retrospective-descriptive study was conducted on children less than 15 years old, with GAS infections, in particular iGAS, and their complications from February 2004-April 2014. RESULTS: A total of 2,192 positive cultures were obtained of which 92...
March 31, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/28359769/regular-in-situ-simulation-training-of-paediatric-medical-emergency-team-leads-to-sustained-improvements-in-hospital-response-to-deteriorating-patients-improved-outcomes-in-intensive-care-and-financial-savings
#15
Ulf Theilen, Laura Fraser, Patricia Jones, Paul Leonard, Dave Simpson
AIM OF THE STUDY: The introduction of a paediatric Medical Emergency Team (pMET) was accompanied by weekly in-situ simulation team training. Key ward staff participated in team training, focusing on recognition of the deteriorating child, teamwork and early involvement of senior staff. Following an earlier study [1], this investigation aimed to evaluate the long-term impact of ongoing regular team training on hospital response to deteriorating ward patients, patient outcome and financial implications...
March 28, 2017: Resuscitation
https://www.readbyqxmd.com/read/28357479/-differences-in-the-outcome-of-seriously-injured-children-depending-on-treatment-level
#16
Peter C Strohm, Jörn Zwingmann, Jörg Bayer, Mirjam V Neumann, Rolf Lefering, Hagen Schmal, Kilian Reising
INTRODUCTION: Many publications, mainly from other countries, suggest that the treatment of seriously injured children might be better in specialised paediatric trauma centres than in general trauma centres. Data from Germany are not available yet, but those from abroad were used for the recommendations made by the German Association for Trauma Surgery (DGU) on the topic of paediatric trauma in the "White Paper on Trauma Care". The goal of this study was to analyse whether the outcome of severely injured children is dependent on treatment level and on the availability of a paediatric surgeon based on the given data...
March 29, 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/28353318/high-flow-nasal-cannula-therapies-for-respiratory-management-in-pediatric-patients
#17
Gang Liu, Conghai Fan, Hongwei Wu
High flow nasal cannula (HFNC) oxygen therapy is a non-invasive form of respiratory support that is rapidly being taken up in paediatric intensive care units (PICU). For infants with bronchiolitis - who are the largest non-elective source of admissions to a PICU - there is some evidence that using HFNC therapy reduces the need for intubation and mechanical ventilation. The aim of this review article is is to explore, describe, critique and add to the evidence surrounding the use of HFNC therapy in the pediatric population for the management of respiratory distress...
March 27, 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/28348428/respiratory-syncytial-virus-infection-rates-with-limited-use-of-palivizumab-for-infants-born-at-29-to-31-6-7-weeks-gestational-age
#18
Brandi Newby, Todd Sorokan
BACKGROUND: Immunoprophylaxis with palivizumab can reduce respiratory syncytial virus (RSV) infections and hospitalizations. Criteria in British Columbia limit the use of palivizumab to infants born at 29 to 31+6/7 weeks gestational age, which differ from guidelines of the American Academy of Pediatrics (AAP) and the Canadian Paediatric Society (CPS). OBJECTIVE: To determine whether the limited use of palivizumab affected the frequency of hospital visits by RSV-positive infants (termed "RSV-positive hospital visits") who received approval for palivizumab and those who met the AAP/CPS criteria but did not receive approval for palivizumab...
January 2017: Canadian Journal of Hospital Pharmacy
https://www.readbyqxmd.com/read/28347624/efficacy-and-safety-of-normal-saline-instillation-and-paediatric-endotracheal-suction-an-integrative-review
#19
REVIEW
Jessica O'Leary, Marion L Mitchell, Marie Cooke, Andreas Schibler
OBJECTIVE: To synthesise research findings regarding the efficacy and safety of normal saline instillation (NSI) during endotracheal suction in the paediatric intensive care unit. DATA SOURCES: The Cochrane Library, PROSPERO, the National Health Service Centre for Reviews and Dissemination, PubMed and Cumulative Index to Nursing and Allied Health (CINAHL) databases were systematically searched. Subject headings included "suctioning, endotracheal", "suction", "sodium chloride", "normal saline" and "paediatrics"...
March 24, 2017: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
https://www.readbyqxmd.com/read/28344164/outbreak-of-brainstem-encephalitis-associated-with-enterovirus-a71-in-catalonia-spain-2016-a-clinical-observational-study-in-a-children-s-reference-centre-in-catalonia
#20
Dídac Casas-Alba, Mariona F de Sevilla, Ana Valero-Rello, Claudia Fortuny, Juan-José García-García, Carlos Ortez, Jordi Muchart, Thais Armangué, Iolanda Jordan, Carles Luaces, Irene Barrabeig, Rubén González-Sanz, María Cabrerizo, Carmen Muñoz-Almagro, Cristian Launes
OBJECTIVES: To describe the characteristics of an outbreak of brainstem encephalitis and encephalomyelitis related to enterovirus (EV) infection in Catalonia (Spain), a setting where these manifestations were uncommon. METHODS: Clinical and microbiological data from patients with neurological symptoms associated with EV detection admitted to a reference paediatric hospital between April and June 2016 were analysed. RESULTS: Fifty-seven patients were included...
March 23, 2017: Clinical Microbiology and Infection
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