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https://www.readbyqxmd.com/read/28511685/respectful-maternity-care-in-ethiopian-public-health-facilities
#1
Ephrem D Sheferaw, Eva Bazant, Hannah Gibson, Hone B Fenta, Firew Ayalew, Tsigereda B Belay, Maria M Worku, Aelaf E Kebebu, Sintayehu A Woldie, Young-Mi Kim, T van den Akker, Jelle Stekelenburg
BACKGROUND: Disrespect and abuse of women during institutional childbirth services is one of the deterrents to utilization of maternity care services in Ethiopia and other low- and middle-income countries. This paper describes the prevalence of respectful maternity care (RMC) and mistreatment of women in hospitals and health centers, and identifies factors associated with occurrence of RMC and mistreatment of women during institutional labor and childbirth services. METHODS: This study had a cross sectional study design...
May 16, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28448223/the-alerrt-%C3%A2-instrument-a-quantitative-measure-of-the-effort-required-to-compromise-prescription-opioid-abuse-deterrent-tablets
#2
Edward J Cone, August R Buchhalter, Karsten Lindhardt, Torben Elhauge, Jeffrey M Dayno
BACKGROUND: US FDA guidance recommends measuring the degree of effort needed to manipulate abuse-deterrent (AD) opioids. The ALERRT(®) instrument (PinneyAssociates; Bethesda, MD) uses visual analog scales to assess the labor, effort, and resources necessary to physically compromise AD product candidates in standardized settings. OBJECTIVE: Use the ALERRT(®) instrument for testing morphine abuse-deterrent, extended-release, injection-molded tablets (ADER-IMT) 60 and 100 mg and the comparators immediate-release (IR) morphine sulfate 30 mg and extended-release (ER) morphine sulfate 60 mg...
May 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28419074/arymo-er-a-new-abuse-deterrent-morphine-formulation
#3
(no author information available yet)
No abstract text is available yet for this article.
April 24, 2017: Medical Letter on Drugs and Therapeutics
https://www.readbyqxmd.com/read/28414990/medical-outcomes-associated-with-prescription-opioid-abuse-via-oral-and-non-oral-routes-of-administration
#4
Jody L Green, Becki Bucher Bartelson, M Claire Le Lait, Carl L Roland, Elizabeth T Masters, Jack Mardekian, J Elise Bailey, Richard C Dart
BACKGROUND: Prescription opioid abuse and misuse is a serious and growing public health issue. While the most common form of abuse is swallowing intact tablets/capsules, some abusers manipulate, or tamper with, these medications by altering the dosage form to allow for non-oral routes of administration (e.g., injection, inhalation) in order to achieve more rapid or enhanced psychoactive effects. Because administration of opioids via non-oral routes results in greater systemic availability and more rapid central nervous system penetration, we hypothesized that death and major medical outcomes occur more frequently with non-oral routes compared to oral route alone...
March 28, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28381914/pharmaceutical-approval-update
#5
Mary Choy
Abuse-deterrent hydrocodone bitartrate (Vantrela ER) for long-term opioid treatment; etelcalcetide (Parsabiv) for secondary hyperparathyroidism in patients with chronic kidney disease on hemodialysis; and deflazacort (Emflaza) for Duchenne muscular dystrophy.
April 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28351350/manifestations-and-drivers-of-mistreatment-of-women-during-childbirth-in-kenya-implications-for-measurement-and-developing-interventions
#6
Charlotte E Warren, Rebecca Njue, Charity Ndwiga, Timothy Abuya
BACKGROUND: Disrespect and abuse or mistreatment of women by health care providers in maternity settings has been identified as a key deterrent to women seeking delivery care. Mistreatment includes physical and verbal abuse, stigma and discrimination, a poor relationship between women and providers and policy and health systems challenges. This paper uses qualitative data to describe mistreatment of women in Kenya. METHODS: Data are drawn from implementation research conducted in 13 facilities and communities...
March 28, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28333577/abuse-deterrent-opioid-formulations-329
#7
Ryann O'Neill, Kimberly Lor, Jennifer Pruskowski
No abstract text is available yet for this article.
March 23, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28318019/corrigendum-the-effect-of-an-abuse-deterrent-opioid-formulation-oxycontin-on-opioid-abuse-related-outcomes-in-the-postmarketing-setting
#8
(no author information available yet)
No abstract text is available yet for this article.
April 2017: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28277802/oxycodone-extended-release-capsules-for-the-treatment-of-chronic-pain
#9
Sebastiano Mercadante
As a consequence of greater prescription opioid utilization, there has been the parallel increase in misuse, abuse, and overdose, which are serious risks. Associated new formulations may be safer. Areas covered: The introduction of abuse-deterrent opioid formulations and continuous programs to improve opioid prescribing practices may limit the opioid abuse and its consequences. Oxycodone extended release capsules are an extended-release (ER), microsphere-in-capsule abuse-deterrent-formulation designed to retain its extended-release properties following tampering or misuse (e...
March 10, 2017: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/28251526/management-of-patients-on-abuse-deterrent-opioids-in-the-ambulatory-surgery-setting
#10
REVIEW
Nalini Vadivelu, Daniel Chang, Leandro Lumermann, Thomas Suchy, Matthew M Burg, Manuel L Fontes
PURPOSE OF REVIEW: The use of prescription opioids for acute and chronic pain has become more prevalent than ever, and concurrent with the increased prescribing of opioids, there has been a steady increase in opioid abuse. Abuse is commonly associated with physical or chemical manipulation of the original opiate to provide more rapid onset of the active ingredient. RECENT FINDINGS: This growing national public health concern has led to the development of various abuse-deterring opioids with the intent of decreasing the diversion of opioids from their prescribed use...
February 2017: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/28243142/secular-trends-in-opioid-prescribing-in-the-usa
#11
Edmund J Pezalla, David Rosen, Jennifer G Erensen, J David Haddox, Tracy J Mayne
Opioid abuse and misuse in the USA is a public health crisis. The use of prescription opioid analgesics increased substantially from 2002 through 2010, then plateaued and began to decrease in 2011. This study examined prescriptions of branded and generic immediate- and extended-release opioid analgesics from 1992 to 2016. This was juxtaposed against state and federal policies designed to decrease overutilization and abuse, as well as the launch of new opioid products, including opioids with abuse-deterrent properties (OADPs)...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28162702/-457-effectiveness-of-hysingla-%C3%A2-er-a-once-daily-single-entity-hydrocodone-with-abuse-deterrent-properties-in-treating-chronic-nonmalignant-and-nonneuropathic-pain-in-patients-with-depression-and-anxiety
#12
S Lynch, L Taber, E He, R Shah
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28162693/-442-pharmacodynamic-data-assessing-the-abuse-potential-of-a-novel-abuse-deterrent-oxycodone-formulation-eli-200-compared-to-oxycodone-immediate-release-oral-intact-eli-200-and-placebo-in-healthy-non-dependent-recreational-opioid-users-following-intranasal
#13
B Setnik, K Schoedel, C Bartlett, C Dick, N Hakim, P Geoffroy
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28162691/-444-clinical-results-of-an-abuse-potential-study-with-remoxy-%C3%A2-an-abuse-deterrent-extended-release-product
#14
L Webster, N Friedmann
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28162680/-430-bioequivalence-and-food-effect-of-a-novel-abuse-deterrent-ad-extended-release-er-morphine-product-candidate-compared-with-a-currently-available-non-ad-er-morphine-product
#15
J Dayno, J Lawler, G Niebler, K Lindhardt
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28162673/-425-dissolution-studies-in-the-presence-of-alcohol-with-an%C3%A2-abuse-deterrent-extended-release-morphine-product-candidate
#16
T Elhauge, L Kristensen, J Dayno, K Lindhardt
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28162671/-422-pharmacodynamic-effects-from-a-category-3-intranasal-human-abuse-potential-study-of-an-abuse-deterrent-extended-release-morphine-product-candidate-in-nondependent-recreational-opioid-users
#17
L Webster, M Smith, J Lawler, K Lindhardt, J Dayno
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28162496/-263-a-model-to-quantify-potential-medical-events-avoided-and-cost-savings-from-abuse-deterrent-opioids
#18
A White, M Yenikomshian, M Carson, E Masters, C Roland
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28162368/-145-relative-abuse-of-abuse-deterrent-formulations-via-alternative-oral-routes
#19
S Butler, R Black, A Fleming
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/27983881/hysingla%C3%A2-er-a-once-daily-single-entity-hydrocodone-with-abuse-deterrent-properties-in-treating-chronic-nonmalignant-and-nonneuropathic-pain-in-patients-with-osteoarthritis
#20
MULTICENTER STUDY
Louise Taber, Stacy Baldridge, Ellie He, Steven R Ripa
OBJECTIVES: Osteoarthritis (OA)-related chronic pain is associated with physical and psychosocial impairment as well as poorer quality of life. There is limited literature on long-term opioid therapy in OA patients. This post hoc analysis of OA patients assessed the long-term safety and effectiveness of a once-daily, single-entity, extended-release formulation of hydrocodone (HYD) with abuse-deterrent properties for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which other treatment options are inadequate...
January 2017: Postgraduate Medicine
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