keyword
MENU ▼
Read by QxMD icon Read
search

Sublingual gland

keyword
https://www.readbyqxmd.com/read/29332268/methylmercury-intoxication-promotes-metallothionein-response-and-cell-damage-in-salivary-glands-of-rats
#1
Leidiane Alencar de Oliveira Lima, Leonardo Oliveira Bittencourt, Bruna Puty, Rafael Monteiro Fernandes, Priscila Cunha Nascimento, Marcia Cristina Freitas Silva, Sérgio Melo Alves-Junior, João de Jesus Viana Pinheiro, Rafael Rodrigues Lima
Environmental and occupational mercury exposure is considered a major public health issue. Despite being well known that MeHg exposure causes adverse effects in several physiologic functions, MeHg effects on salivary glands still not completely elucidated. Here, we investigated the cellular MeHg-induced damage in the three major salivary glands (parotid, submandibular, and sublingual) of adult rats after chronic, systemic and low doses of MeHg exposure. Rats were exposed by 0.04 mg/kg/day over 60 days. After that, animals were euthanized and all three glands were collected...
January 14, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29283518/digestive-and-nondigestive-functions-of-rodents-salivary-glands
#2
V V Ivanova, I V Milto, I V Sukhodolo, O N Serebryakova, A V Buzenkova
Major salivary glands play a role not only in digestion, but also in regulation of other functions in rodents. In this review, we analyzed and summarized the data about the rodents' parotid, submandibular and sublingual salivary glands functions, which is not limited to the production of saliva and action of its hydrolytic enzymes on food in the oral cavity. In recent decades significantly expanded understanding of major salivary glands nondigestive functions. They are involved in excretion of metabolic products, maintaining fluid and electrolyte balance...
January 2017: Uspekhi Fiziologicheskikh Nauk
https://www.readbyqxmd.com/read/29219039/morphogenesis-and-mucus-production-of-epithelial-tissues-of-three-major-salivary-glands-of-embryonic-mouse-in-3d-culture
#3
Azusa Nakao, Takumi Inaba, Akiko Murakami-Sekimata, Hiroyuki Nogawa
Embryonic mouse submandibular epithelia initiate branching morphogenesis within two days when embedded in Matrigel and stimulated by members of the epidermal growth factor family. However, it is unknown whether the end buds further branch over longer culture periods, and whether saliva-producing cells differentiate there. In the present study, we cultivated three major (submandibular, sublingual and parotid) salivary epithelia from 13-day embryos for 14 days in mesenchyme-free cultures. All epithelia continued to grow and branch to form numerous acinus-like structures in medium supplemented with neuregulin 1, fibroblast growth factor 1, and insulintransferrin-sodium selenite...
December 2017: Zoological Science
https://www.readbyqxmd.com/read/29197149/cd29-is-highly-expressed-on-epithelial-myoepithelial-and-mesenchymal-stromal-cells-of-human-salivary-glands
#4
Padma Priya Togarrati, Nuntana Dinglasan, Shivani Desai, William R Ryan, Marcus O Muench
OBJECTIVE: The phenotype of the cells present in the ductal region of salivary glands have been well characterized. However, it is imperative to identify novel biomarkers that can identify different cell types present in other glandular components for the development of therapeutic strategies and diagnostics of salivary gland disorders and malignancies. Our study aimed at the characterization of the expression and distribution of various cell surface markers, especially with a focus on CD29 in human fetal as well as adult glands...
December 2, 2017: Oral Diseases
https://www.readbyqxmd.com/read/29183011/transoral-robotic-surgery-with-sialendoscopy-for-a-plunging-ranula
#5
Ryan M Carey, Benjamin L Hodnett, Christopher H Rassekh, Gregory S Weinstein
BACKGROUND/AIMS: Plunging ranulas are oral mucoceles that often cannot be visualized directly and thus can be challenging to diagnose and differentiate from other neck lesions. Surgery is the preferred treatment option, but the optimal approach requires careful consideration. METHODS: We report the case of a plunging ranula presenting as an isolated neck mass in a 33-year-old patient. This patient was treated with a novel transoral robotic surgery (TORS)-assisted approach aided by sialendoscopy...
November 29, 2017: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/29181608/immunolocalization-patterns-of-cytokeratins-during-salivary-acinar-cell-development-in-mice
#6
Nirpesh Adhikari, Sanjiv Neupane, Jiyeon Roh, Jong Hwa Jun, Jae-Kwang Jung, Wern-Joo Sohn, Jae-Young Kim, Ji-Youn Kim
Embryonic development of the mouse salivary glands begins with epithelial thickening and continues with sequential changes from the pre-bud to terminal bud stages. After birth, morphogenesis proceeds, and the glands develop into a highly branched epithelial structure that terminates with saliva-producing acinar cells at the adult stage. Acinar cells derived from the epithelium are differentiated into serous, mucous, and seromucous types. During differentiation, cytokeratins, intermediate filaments found in most epithelial cells, play vital roles...
November 27, 2017: Journal of Molecular Histology
https://www.readbyqxmd.com/read/29169627/cytomegalic-inclusion-disease-caused-by-cytomegalovirus-infection-in-the-salivary-glands-of%C3%A2-an-african-hedgehog-atelerix-arbiventris
#7
K Koyama, N Horiuchi, H Hasegawa, H Katano, E Oohashi, K Watanabe, Y Kobayashi
Cytomegalic inclusion disease (CID) in the salivary gland of African hedgehogs (Atelerix arbiventris) has been reported before, and is suspected to reflect a cytomegalovirus infection. However, a recent ultrastructural study reported that African hedgehog CID reflected oncocytic metaplasia, mimicking a cytomegalovirus infection. We examined the submandibular and sublingual salivary glands of a 1-year-old male African hedgehog. Histologically, there were multiple foci composed of cytomegalic cells with intranuclear inclusion bodies...
November 2017: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/29152292/concomitant-occurrence-of-primary-hyperparathyroidism-phpt-due-to-mediastinal-parathyroid-adenoma-and-sublingual-thyroid-gland-the-role-of-parathyroid-technetium-99m-mibi-scintigraphy
#8
Sara Choukry, Jaafar Benouhoud, Ghofrane Cherkaoui Salhi, Sara Taleb, Amal Guensi, Karim Choukry
The concomitant appearance of a sublingual thyroid and primary hyperparathyroidism due to parathyroid mediastinal adenoma is not common. This co-occurrence can lead to a misdiagnosis by morphological imaging methods alone. This case emphasizes the role of 99mTc-MIBI scintigraphy in the detection of parathyroid ectopic adenoma in a patient with an ectopic thyroid gland. This more accurate location of parathyroid scintigraphy is of great benefit to the surgeon for surgical excision.
November 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/29124004/papillary-cystadenocarcinoma-of-the-sublingual-gland
#9
Neil Giblett, Syed Farhan Ahsan, Ahmed Messahel
A 68-year-old Caucasian gentleman presented with a 6-month history of a left sided Level I/II neck swelling involving the floor of mouth. MRI revealed a large cystic lesion and histology confirmed a diagnosis of primary papillary cystadenocarcinoma of the sublingual gland. Papillary cystadenocarcinoma was first described in 1991 by the World Health Organisation [WHO], and is a rare malignant neoplasm characterised by cysts and papillary endo-cystic projections. Papillary cystadenocarcinoma arising from the sublingual glands is extremely rare and has the potential to metastasise to cervical lymph nodes...
September 2017: Journal of Oral Biology and Craniofacial Research
https://www.readbyqxmd.com/read/29051343/iodinated-contrast-agents-perturb-iodide-uptake-by-the-thyroid-independently-of-free-iodide
#10
Georges Vassaux, Colette Zwarthoed, Laurie Signetti, Julien Guglielmi, Catherine Compin, Jean-Marie Guigonis, Thierry Juhel, Olivier Humbert, Danielle Benisvy, Thierry Pourcher, Beatrice Cambien
The perturbation of thyroid iodide uptake is a well-documented side effect of the utilization of iodinated contrast media (ICM) administrated intravenously. This side effect is thought to be mediated by free iodide in ICM formulations but this hypothesis has never been formally demonstrated. The aim of the present paper is to assess the validity of this hypothesis. Methods: We used mass spectrometry analysis to quantify free-iodide contamination in ICM. Established cell lines expressing the Na/I symporter (NIS) were used to quantify the effect of ICM on iodide uptake...
October 19, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28974881/ectopic-salivary-gland-cyst-in-the-neck-association-with-congenital-plunging-ranula
#11
Nitin Pant, Ajay Kumar Verma, Tanvir Rashan Khan, Ashish Wakhlu
Congenital ranula is rare. We report a large, symptomatic, congenital plunging ranula associated with a salivary gland cyst in the neck. To the best of our knowledge, this is the first such reported case. Even though both the cysts had their origin from the sublingual gland, only the cervical cyst had a capsular covering. Herniation of a part of the immature sublingual gland anlage through a congenital mylohyoid defect, its separation, and subsequent maturation could explain this occurrence.
October 2017: Journal of Indian Association of Pediatric Surgeons
https://www.readbyqxmd.com/read/28969884/prognostic-factors-in-head-and-neck-mucoepidermoid-carcinoma-experience-at-a-single-institution-based-on-64-consecutive-patients-over-a-28-year-period
#12
M Granic, P Suton, D Mueller, I Cvrljevic, I Luksic
Mucoepidermoid carcinoma (MEC) is the most common malignancy of the salivary glands. The clinical behaviour of MEC is largely unpredictable, ranging from indolent tumour growth to highly aggressive metastatic spread. The objective of this study was to determine the clinicopathological predictors of recurrence and survival in patients with head and neck MEC. The medical records of 64 patients who underwent surgical treatment for head and neck MEC between 1982 and 2010 were reviewed. The main outcome measures were disease-free survival (DFS) and overall survival (OS)...
September 29, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28938886/congenital-hypothyroidism-due-to-ectopic-sublingual-thyroid-gland-in-prader-willi-syndrome-a-case-report
#13
Sarah Bocchini, Danilo Fintini, Graziano Grugni, Arianna Boiani, Alessio Convertino, Antonino Crinò
BACKGROUND: Thyroid gland disorders are variably associated with Prader-Willi syndrome (PWS). Many of the clinical features in newborns with PWS are similar to those found in congenital hypothyroidism (CH). CASE PRESENTATION: We report a case of a girl with CH and PWS. At the age of 9 months CH caused by an ectopic sublingual thyroid was diagnosed, and hormone replacement therapy was started. In spite of this treatment a decrease in growth velocity, weight excess and delayed development were observed...
September 22, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/28927048/mucoepidermoid-carcinoma-of-the-sublingual-gland-harboring-a-translocation-of-the-maml2-gene-a-case-report
#14
Kiminobu Sato, Jun Akiba, Ken Nakamura, Hideyuki Abe, Akihiko Kawahara, Takeichiro Aso, Hirohito Umeno, Hiroshi Harada, Hirohisa Yano
Among tumors of the major salivary glands, tumors in the sublingual gland are rare. Although mucoepidermoid carcinoma (MEC) represents a histological type of salivary gland tumor, it is occasionally difficult to diagnose due to its histological variation. The present study reports a case of MEC harboring a mastermind-like transcriptional coactivator 2 (MAML2) gene translocation in the sublingual gland. A 76-year-old Japanese woman with a mass in the left submandibular region was referred to Kurume University Hospital (Kurume, Japan)...
September 2017: Oncology Letters
https://www.readbyqxmd.com/read/28914590/canine-salivary-glands-analysis-of-rab-and-snare-protein-expression-and-snare-complex-formation-with-diverse-tissue-properties
#15
Hiroshi Gomi, Hiromi Osawa, Rie Uno, Tadashi Yasui, Masahiro Hosaka, Seiji Torii, Azuma Tsukise
The comparative structure and expression of salivary components and vesicular transport proteins in the canine major salivary glands were investigated. Histochemical analysis revealed that the morphology of the five major salivary glands-parotid, submandibular, polystomatic sublingual, monostomatic sublingual, and zygomatic glands-was greatly diverse. Immunoblot analysis revealed that expression levels of α-amylase and antimicrobial proteins, such as lysozyme, lactoperoxidase, and lactoferrin, differed among the different glands...
November 2017: Journal of Histochemistry and Cytochemistry: Official Journal of the Histochemistry Society
https://www.readbyqxmd.com/read/28903405/uptake-of-psma-ligands-in-normal-tissues-is-dependent-on-tumor-load-in-patients-with-prostate-cancer
#16
Florian C Gaertner, Khalil Halabi, Hojjat Ahmadzadehfar, Stefan Kürpig, Elisabeth Eppard, Charalambos Kotsikopoulos, Nikolaos Liakos, Ralph A Bundschuh, Holger Strunk, Markus Essler
Radioligand therapy (RLT) with Lu-177-labeled PSMA-ligands is a new therapy option for prostate cancer. Biodistribution in normal tissues is of interest for therapy planning. We evaluated if the biodistribution of Ga-68-PSMA-11 is influenced by tumor load. RESULTS: In patients with high tumor load, SUVmean was reduced to 61.5% in the lacrimal glands, to 56.6% in the parotid glands, to 63.7% in the submandibular glands, to 61.3% in the sublingual glands and to 55.4% in the kidneys (p < 0...
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28899226/adenoid-cystic-carcinoma-of-the-head-and-neck-a-retrospective-multicenter-study
#17
Shinji Takebayashi, Shogo Shinohara, Hisanobu Tamaki, Ichiro Tateya, Morimasa Kitamura, Masanobu Mizuta, Shinzo Tanaka, Tsuyoshi Kojima, Ryo Asato, Toshiki Maetani, Koji Ushiro, Yoshiharu Kitani, Kazuyuki Ichimaru, Keigo Honda, Koichiro Yamada, Koichi Omori
BACKGROUND: Adenoid cystic carcinoma of the head and neck (ACCHN) is rare and difficult to study effective treatment at one institute. Our aim is to identify prognostic factors for this disease by conducting a multicenter study at 11 institutions in Japan. METHODS: A retrospective multicenter study of ACCHN was performed. One hundred and three patients were identified between 2006 and 2015. The overall survival (OS) rate for all patients was calculated, and OS, locoregional control (LRC) rate, or no distant metastasis (NDM) rate was calculated for patients in that the surgery was performed without distant metastasis (DM)...
September 12, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28898113/interferon-regulatory-factor-6-is-necessary-for-salivary-glands-and-pancreas-development
#18
K A Metwalli, M A Do, K Nguyen, S Mallick, K Kin, N Farokhnia, G Jun, W D Fakhouri
Interferon regulatory factor 6 ( IRF6) acts as a tumor suppressor and controls cell differentiation in ectodermal and craniofacial tissues by regulating expression of target genes. Haploinsufficiency of IRF6 causes Van der Woude and popliteal pterygium syndrome, 2 syndromic forms of cleft lip and palate. Around 85% of patients with Van der Woude express pits on the lower lip that continuously or intermittently drain saliva, and patients with the common cleft lip and palate have a higher prevalence of dental caries and gingivitis...
September 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28891012/visualization-of-multiple-organ-amyloid-involvement-in-systemic-amyloidosis-using-11-c-pib-pet-imaging
#19
Naoki Ezawa, Nagaaki Katoh, Kazuhiro Oguchi, Tsuneaki Yoshinaga, Masahide Yazaki, Yoshiki Sekijima
PURPOSE: To investigate the utility of Pittsburgh compound B (PiB) positron emission tomography (PET) imaging for evaluating whole-body amyloid involvement in patients with systemic amyloidosis. METHODS: Whole-body (11)C-PiB PET was performed in seven patients with systemic immunoglobulin light-chain (AL) amyloidosis, seven patients with hereditary transthyretin (ATTRm) amyloidosis, one asymptomatic TTR mutation carrier and three healthy controls. The correlations between clinical organ involvement, radiological (11)C-PiB uptake and histopathological findings were analysed for each organ...
September 10, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28872990/plunging-ranula-occurring-without-its-oral-counterpart-a-case-report
#20
K Shah Arpan, Padmaja Ankur, K Thakkur Rahul
A ranula is a lesion that arises from mucin spillage from the sublingual or submandibular gland ducts, beneath the mucosa of the oral floor. A plunging or cervical ranula dissects the mylohyoid muscle and appears as a submandibular swelling. Rarely, a plunging ranula is encountered without its oral counterpart. Here, we report a rare case of a plunging ranula that occurred without its oral counterpart in a 11-year-old male patient. We have also discussed the pathogenesis and treatment options for the ranula...
2017: Journal of Clinical Pediatric Dentistry
keyword
keyword
4316
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"