Mengqiang Gong, Zhi Li, Hua Xu, Bo Ma, Pengxia Gao, Lili Wang, Junkai Li, Qinglai Wu, Jianfeng Wu, Jianwei Xie
Amanita phalloides is one of the deadliest mushrooms worldwide, causing most fatal cases of mushroom poisoning. Among the poisonous substances of Amanita phalloides, amanitins are the most lethal toxins to humans. Currently, there are no specific antidotes available for managing amanitin poisoning and treatments are lack of efficacy. Amanitin mainly causes severe injuries to specific organs, such as the liver, stomach, and kidney, whereas the lung, heart, and brain are hardly affected. However, the molecular mechanism of this phenomenon remains not understood...
April 17, 2024: Food and Chemical Toxicology