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Flushing in adults

Cheng Huang, Xiong-Wen Lv, Tao Xu, Ming-Ming Ni, Jia-Lu Xia, Shuang-Peng Cai, Qun Zhou, Xing Li, Yang Yang, Lei Zhang, Hong-Wei Yao, Xiao-Ming Meng, Hua Wang, Jun Li
BACKGROUND: An increase in alcohol consumption and related harmful effects has been reported among the elderly population in Asia. Of note, it is important to monitor patterns of alcohol use, and to establish a valid and reliable evaluation system when screening for risky consumption in this age group. OBJECTIVE: The aim of the current study was to evaluate the possible alcoholic liver disease (ALD) risk factors of a local population in elderly Chinese adults. METHODS: A questionnaire was sent to 3393 Chinese adults over 40 years old in Hefei...
August 12, 2017: Alcohol
Makiko Abe, Nitin Shivappa, Hidemi Ito, Isao Oze, Tetsuya Abe, Yasuhiro Shimizu, Yasuhisa Hasegawa, Chikako Kiyohara, Masatoshi Nomura, Yoshihiro Ogawa, James R Hebert, Keitaro Matsuo
Background: The inflammatory potential of diet that has been shown to be associated with cancer risk. We examined the association between dietary inflammatory potential as measured by the dietary inflammatory index (DII® ) and risk of upper aerodigestive tract cancers in a Japanese case-control study. Results: A positive association was observed between increasing DII scores and overall upper aerodigestive tract cancers, and across anatomic subsites. For upper aerodigestive tract cancers, the ORQ4vsQ1 = 1...
May 8, 2018: Oncotarget
Mohamed Tharwat, Mohamed M Elsaadany, Ahmed M Lashin, Ahmed R El-Nahas
PURPOSE: To evaluate the role of sildenafil in relieving ureteral stent symptoms. PATIENTS AND METHODS: A randomized controlled trial was conducted between March 2014 and November 2016. It included adult men who underwent unilateral ureteric stent after ureteroscopy. Patients who were taking PDE5-Is, alpha-blockers or anticholinergics, had contraindication to sildenafil or developed postoperative complications were not included. Eligible patients were randomized using sealed closed envelops to one of two groups (S and C)...
May 15, 2018: World Journal of Urology
Michael C Singer, Camille Parmesan
Global transport of organisms by humans provides novel resources to wild species, which often respond maladaptively. Native herbivorous insects have been killed feeding on toxic exotic plants, which acted as 'ecological traps'1-4 . We document a novel 'eco-evolutionary trap' stemming from the opposite effect; that is, high fitness on an exotic resource despite lack of adaptation to it. Plantago lanceolata was introduced to western North America by cattle-ranching. Feeding on this exotic plant released a large, isolated population of the native butterfly Euphydryas editha from a longstanding trade-off between maternal fecundity and offspring mortality...
May 2018: Nature
Martin J Gilbert, Michael J Samways
Scirtothrips aurantii Faure (Thysanoptera: Thripidae) is a major pest of citrus fruit in subtropical southern Africa. Population monitoring is an important aspect of S. aurantii control, but additional information is required on its phenology. Dispersal of mature larvae onto the soil surface from the tree canopy, and emergence of adults, were assessed using dispersal/emergence (D/E) traps in an untreated citrus orchard in South Africa. Overall, 90.7% of adult Thysanoptera emerging from soil / leaf litter beneath the citrus trees were S...
March 1, 2018: Journal of Insect Science
Canqing Yu, Yu Guo, Zheng Bian, Ling Yang, Iona Y Millwood, Robin G Walters, Yiping Chen, Yan Chen, Xi Zhang, Yulong Lei, Junshi Chen, Zhengming Chen, Jun Lv, Liming Li
Existing evidence remains inconclusive as to how the association between inactive ALDH2 and esophageal cancer (EC) depends on alcohol consumption. The study is based on the China Kadoorie Biobank cohort, with 10 years follow-up of 0.5 million adults aged 30-79 years. ALDH2 activity was assessed by both self-reported flushing response and Glu504Lys (rs671 G > A) polymorphism. Among both male and female participants who consumed alcohol less than weekly (n = 69,519; 211 EC cases), low active or inactive ALDH2 was not associated with increased EC risk [HRs (95% CIs): GA vs...
April 29, 2018: International Journal of Cancer. Journal International du Cancer
Raed Alroughani, Rajiv Das, Natasha Penner, Joe Pultz, Catherine Taylor, Satish Eraly
BACKGROUND: No therapies have been formally approved by the Food and Drug Administration for use in pediatric multiple sclerosis, a rare disease. OBJECTIVE: We evaluated the safety, efficacy, and pharmacokinetics of dimethyl fumarate in pediatric patients with multiple sclerosis. METHODS: FOCUS, a phase 2, multicenter study of patients aged 10 to 17 years with relapsing-remitting multiple sclerosis, comprised an eight-week baseline and 24-week treatment period; during treatment, patients received dimethyl fumarate (120 mg twice daily on days one to seven; 240 mg twice a day thereafter)...
June 2018: Pediatric Neurology
Heidi R Waite, Melinda J Donnelly, Linda J Walters
This study determined the quantity and diversity of microplastics in water and soft tissues of eastern oysters (Crassostrea virginica) and Atlantic mud crabs (Panopeus herbstii) in Mosquito Lagoon, a shallow, microtidal estuary along the east coast of central Florida. One-liter water samples had an average of 23.1 microplastic pieces (n = 15). Crabs (n = 90) had an average of 4.2 pieces in tissues/individual plus an average of 20.3 pieces/individual temporarily entangled in exposed surfaces and released within 5 days in tanks...
April 2018: Marine Pollution Bulletin
Sharon J Gardiner, Sarah Cl Metcalf, Paul Kl Chin, Matthew P Doogue, Simon C Dalton, Stephen T Chambers
AIMS: To evaluate an antimicrobial stewardship (AMS) initiative to change hospital prescribing practice for metronidazole. METHODS: In October 2015, the Canterbury District Health Board (CDHB) AMS committee changed advice for metronidazole to promote two times daily dosing for most indications, prioritisation of the oral route and avoidance of double anaerobic cover. Adoption of the initiative was facilitated via change in prescribing guidelines, education and ongoing pharmacy support...
April 13, 2018: New Zealand Medical Journal
Mathias B Forrester
INTRODUCTION: The Megalopyge opercularis caterpillar is covered with spines that break off and release venom on contact, resulting in severe pain, erythema, rash, and other adverse effects. In Texas, these caterpillars are abundant and of potential health threat. This study describes M opercularis caterpillar stings reported to Texas poison centers. METHODS: Cases were M opercularis caterpillar stings reported to Texas poison centers during 2000-2016. The distribution of stings was determined related to exposure circumstances and management...
June 2018: Wilderness & Environmental Medicine
Eric S Michel, Jonathan A Jenks, Kyle D Kaskie, Robert W Klaver, William F Jensen
Offspring survival is generally more variable than adult survival and may limit population growth. Although white-tailed deer neonate survival has been intensively investigated, recent work has emphasized how specific cover types influence neonate survival at local scales (single study area). These localized investigations have often led to inconsistences within the literature. Developing specific hypotheses describing the relationships among environmental, habitat, and landscape factors influencing white-tailed deer neonate survival at regional scales may allow for detection of generalized patterns...
2018: PloS One
Irene Bighelli, Mariasole Castellazzi, Andrea Cipriani, Francesca Girlanda, Giuseppe Guaiana, Markus Koesters, Giulia Turrini, Toshi A Furukawa, Corrado Barbui
BACKGROUND: Panic disorder is characterised by repeated, unexpected panic attacks, which represent a discrete period of fear or anxiety that has a rapid onset, reaches a peak within 10 minutes, and in which at least four of 13 characteristic symptoms are experienced, including racing heart, chest pain, sweating, shaking, dizziness, flushing, stomach churning, faintness and breathlessness. It is common in the general population with a lifetime prevalence of 1% to 4%. The treatment of panic disorder includes psychological and pharmacological interventions...
April 5, 2018: Cochrane Database of Systematic Reviews
Himanshu Adlakha, Ruchi Gupta, Romana Hassan, Jeffrey H Kern
BACKGROUND: Vasovagal syncope is the most common cause of syncope in children and adults, accounting for 50-66% of unexplained syncope. There are no studies establishing the relationship between syncope, baseline heart rate, and blood pressure. OBJECTIVE: To identify a possible association between baseline blood pressure and heart rate with syncope. DESIGN/METHODS: We conducted a questionnaire-based chart review study. A questionnaire was distributed to the guardian of children between eight and 18 years of age who attended the Pediatric Ambulatory Care Clinic at Flushing Hospital Medical Center...
January 28, 2018: Curēus
George A Fisher, Edward M Wolin, Nilani Liyanage, Susan Pitman Lowenthal, Beloo Mirakhur, Rodney F Pommier, Montaser Shaheen, Aaron I Vinik
OBJECTIVE: This ELECT prospective analysis examined lanreotide depot/autogel for carcinoid syndrome (CS) symptom control in patients with neuroendocrine tumors (NETs) who were responsive to prior octreotide (prior octreotide group) compared with patients who were naïve to prior somatostatin analogue treatment (de novo group). METHODS: Adults with histopathologically confirmed NET and stable CS (diarrhea and/or flushing) were randomized to subcutaneous (SC) lanreotide 120 mg or placebo every 4 weeks for 16 weeks...
March 2018: Endocrine Practice
Jeffrey L Jarvis, John Gonzales, Danny Johns, Lauren Sager
STUDY OBJECTIVE: Peri-intubation hypoxia is an important adverse event of out-of-hospital rapid sequence intubation. The aim of this project is to determine whether a clinical bundle encompassing positioning, apneic oxygenation, delayed sequence intubation, and goal-directed preoxygenation is associated with decreased peri-intubation hypoxia compared with standard out-of-hospital rapid sequence intubation. METHODS: We conducted a retrospective, before-after study using data from a suburban emergency medical services (EMS) system in central Texas...
March 9, 2018: Annals of Emergency Medicine
R Olivera, L N Moro, R Jordan, N Pallarols, A Guglielminetti, C Luzzani, S G Miriuka, G Vichera
Introduction: Cell plasticity is crucial in cloning to allow an efficient nuclear reprogramming and healthy offspring. Hence, cells with high plasticity, such as multipotent mesenchymal stem cells (MSCs), may be a promising alternative for horse cloning. In this study, we evaluated the use of bone marrow-MSCs (BM-MSCs) as nuclear donors in horse cloning, and we compared the in vitro and in vivo embryo development with respect to fibroblasts. Materials and methods: Zona-free nuclear transfer was performed using BM-MSCs (MSC group, n=3432) or adult fibroblasts (AF group, n=4527)...
2018: Stem Cells and Cloning: Advances and Applications
Munashe Livion Nyika, Doreen Mukona, Mathilda Zvinavashe
This descriptive survey identified factors contributing to phlebitis among 46 adult inpatients using a systematic random sample. The visual infusion phlebitis score was used for assessment. All participants had phlebitis, with stage 4 being most frequent. Factors identified were gender (males-91.7%); immunosuppression (human immunodeficiency virus-63.0%; diabetes-100%; immunosuppressive drugs-100%; absolute leucocyte count <1000 μL-100%); number of catheters inserted (>1-90.9%); site of catheterization (dorsum of wrist-100%); catheter dwell time (2-4 days-100%); catheter gauge (18-gauge-75%); catheter securement (unsecured/contaminated dressing-90%); regularity of catheter flushing (catheter never flushed-72...
March 2018: Journal of Infusion Nursing: the Official Publication of the Infusion Nurses Society
K W Langdon, R Schumann, L L Stelinski, M E Rogers
Neonicotinoids are a key group of insecticides used to manage Diaphorina citri Kuwayama (Hemiptera: Liviidae), in Florida citrus. Diaphorina citri is the vector of Candidatus Liberibacter asiaticus, the presumed causal agent of huanglongbing, a worldwide disease of citrus. A two-season field study was conducted to evaluate the effect of tree size and application rate on the expression of thiamethoxam in young citrus following application to the soil. D. citri adult and nymph abundance was also correlated with thiamethoxam titer in leaves...
April 2, 2018: Journal of Economic Entomology
Julie Harper, James Q Del Rosso, Ilia L Ferrusi
Rosacea is a chronic skin condition characterized by persistent central facial erythema. To explore the burden of illness of rosacea in US adults, a cross-sectional web-based survey was conducted. Participants answered questions on sociodemographics, clinical characteristics, bothersome symptoms, coping and avoidance behaviors, self-perceptions, and health care resource utilization, and completed 2 quality of life instruments, the 21-item rosacea-specific quality of life questionnaire (RosaQoL) and the 36-item Short Form Health Survey (SF-36)...
February 1, 2018: Journal of Drugs in Dermatology: JDD
Francisco Dávila, Anne Botteaux, David Bauman, Sarah Chérasse, Serge Aron
Bacteria can damage sperm and thus reduce the reproductive success of both males and females; selection should therefore favour the evolution of antimicrobial protection. Eusocial hymenopterans might be particularly affected by such bacterial infections because of their mating ecology. In both sexes, mating is restricted to a short window early in the adult stage; there are no further chances to mate later in life. Males die shortly after mating, but queens use the acquired sperm to fertilise their eggs for years, sometimes decades...
March 26, 2018: Journal of Experimental Biology
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