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parotid adenoma

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https://www.readbyqxmd.com/read/29141486/recurrent-pleomorphic-adenoma-is-treatment-considerably-delayed-thus-affecting-surgical-morbidity
#1
Eran Glikson, Doron Sagiv, Jobran Mansour, Lev Bedrin, Yoav P Talmi, Eran E Alon
OBJECTIVE: To examine the incidence of late presentation of patients with recurrent pleomorphic adenoma (RPA) of the parotid gland. METHODS: This is a retrospective analysis of patients treated in our center. We examined patients demographics, disease characteristics, treatment, and outcome and as well as the time period length from the first discovery of a recurrent mass until seeking treatment at our clinic and its effect on morbidity. RESULTS: A total of 30 patients were included...
November 16, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29116049/pleomorphic-adenoma-the-results-of-a-retrospective-analysis-of-104-patients-treated-at-the-clinical-department-of-cranio-maxillofacial-surgery-clinic-of-otolaryngology-and-laryngologic-oncology-of-the-military-institute-of-medicine
#2
Michał Korba, Aldona Chloupek, Jarosław Dąbrowski, Tomasz Piętka, Wojciech Domański, Barbara Biernacka, Wojciech Leśniak
Pleomorphic adenoma, also known as tumor mixtus, is one of the most common types of benign neoplasm of the salivary gland, which presents as a slow growing, painless tumor. Major salivary glands are the typical localization of this neoplasm. It rarely undergoes malignant transformation, however may recur locally post resection. In this study, we present the results of a retrospective analysis of 104 patients treated at the Clinical Department of Cranio-Maxillofacial Surgery, Clinic of Otolaryngology and Laryngologic Oncology of the Military Institute of Medicine between 2004 and 2015 due to pleomorphic adenoma...
August 31, 2017: Otolaryngologia Polska
https://www.readbyqxmd.com/read/29112638/the-role-of-real-time-sonoelastography-in-the-differentiation-of-benign-from-malignant-parotid-gland-tumors
#3
Sumeyra Cortcu, Muzaffer Elmali, Asli Tanrivermis Sayit, Yuksel Terzi
OBJECTIVE: The aims of this study are to evaluate the utility of sonoelastography for parotid gland masses and to determine which cutoff strain ratio (SR) would be best for the differentiation between benign and malignant lesions. METHODS: From August 2015 to December 2016, 39 parotid gland masses were examined prospectively by ultrasonography and strain sonoelastography. Elastographic scores were determined by a 4-point scoring method. Interventional procedures were performed on all patients after sonographic examinations...
November 6, 2017: Ultrasound Quarterly
https://www.readbyqxmd.com/read/29097817/comparison-of-lymphatic-vessel-density-and-expression-of-vegf-c-and-vegf-d-lymphangiogenic-factors-in-warthin-s-tumours-and-oncocytic-adenomas
#4
Jiri Hoza, Richard Salzman, Tomas Bakaj, Ladislava Kucerova, Ivo Starek
OBJECTIVES: To compare the density of lymphatic vessels and VEGF-C and VEGF-D expression in Warthin's tumours (WTs) and oncocytic adenomas (OCAs). METHODS: Twenty three WTs and 13 OCAs of the parotid gland were analyzed. Lymphatic vessels were detected using the D2-40 antibody. For evaluation of the intratumour and peritumour lymphatic vessel density (iLVD and pLVD, respectively) the area of greatest vascularisation (hot spots) was chosen, using a ×40 field, and the number of vessels per square millimeter was counted in a ×200 field...
November 2, 2017: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
https://www.readbyqxmd.com/read/29095193/the-effectiveness-of-sternocleidomastoid-flap-versus-superficial-musculoaponeurotic-system-flap-for-the-prevention-of-frey-syndrome-and-facial-depressed-deformity-in-parotid-surgery-for-pleomorphic-adenoma
#5
Marco Manola, Luca Moscillo, Vittorio Simeon, Elena De Luca, Americo Mastella
The purpose of this study was to compare 2 types of reconstruction techniques: sternocleidomastoid (SCM) flap and superficial musculoaponeurotic system (SMAS) flap after partial parotidectomy (PP) for preventing Frey syndrome (FS) and concave facial depressed deformity. A total of 99 patients underwent PP for pleomorphic adenoma of the parotid gland. The patients were divided in 2 groups according to the dimension of the tumor: tumors less than 3 cm (group A, 47 patients) and tumors greater than or equal to 3 cm (group B, 52 patients)...
October 31, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29055657/correlation-between-computed-tomography-imaging-and-histopathology-in-pleomorphic-adenoma-of-parotid-gland
#6
Heejin Kim, So Young Kim, Yoon-Joong Kim, Jae-Mun Ko, Min Ji Park, Ji Hoon Kim, J Hun Hah, Tack-Kyun Kwon, Kwang Hyun Kim, Myung-Whun Sung
OBJECTIVE: The purpose of this study was to correlate the CT imaging features and histopathological findings of pleomorphic adenomas (PA), and also try to identify its clinical significance. METHODS: Totally 262 PAs in the parotid gland including 18 recurrent cases were retrospectively reviewed with preoperative CT and pathologic slides. Each pathologic slide was reviewed by two pathologists to calculate mean value of epithelial/mesenchymal component, and the results were correlated with features of CT scans...
October 18, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29038635/pleomorphic-adenoma-of-soft-palate-unusual-occurrence-of-the-major-tumor-in-minor-salivary-gland-a-case-report-and-literature-review
#7
Deepak Passi, Hari Ram, Shubha Ranjan Dutta, Laxman Revansidha Malkunje
Salivary gland tumours constitute about less than 4 % of all head and neck tumours. Pleomorphic adenoma, also called benign mixed tumour, is the most common tumour of the salivary glands. About 80-90 % of these tumours occur in the major salivary glands mainly parotid gland and 10 % of them occur in the minor salivary glands. The most common site for pleomorphic adenoma of the minor salivary glands is the palate, followed by the lips and the cheeks. Other rare sites include the floor of the mouth, tongue, tonsil, pharynx, retromolar area and the nasal cavity...
December 2017: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/29026716/benign-recurrent-pleomorphic-adenoma-of-the-parotid-gland-with-perineural-space-invasion
#8
EDITORIAL
Luca Roncati, Antonio Maiorana
No abstract text is available yet for this article.
September 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/28987676/value-of-diffusion-tensor-imaging-in-differentiating-malignant-from-benign-parotid-gland-tumors
#9
Koji Takumi, Yoshihiko Fukukura, Hiroto Hakamada, Junichi Ideue, Yuichi Kumagae, Takashi Yoshiura
PURPOSE: To evaluate whether diffusion tensor imaging (DTI) can be used to differentiate malignant parotid gland tumors from the benign ones. MATERIALS AND METHODS: The study population comprised 59 parotid gland tumors (24 Warthin's tumors, 19 pleomorphic adenomas, seven other benign tumors, and nine malignant tumors). Single-shot echo-planar DTI was performed with motion-probing gradients along 30 noncollinear directions (b=1000s/mm(2)) at 3.0T. Apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values for benign and malignant tumors were compared using the Mann-Whitney U test...
October 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28987229/controversies-in-oral-and-maxillofacial-oncology
#10
REVIEW
Jacob G Yetzer
Imaging studies are essential components of tumor diagnosis, staging, assessing tumor response to neoadjuvant and adjuvant therapies, and postoperative surveillance on completion of definitive treatment. Treatment of early stage clinically node negative oral cavity squamous cell carcinoma is controversial. Approximately 3% of all head and neck tumors arise within the parotid gland and most often within the superficial lobe, lateral to the facial nerve; about 80% are benign and most are pleomorphic adenoma. In patients with dry eyes failing multiple other treatment modalities and facing ongoing pain and loss of vision, microvascular transplant of the submandibular gland is a viable option...
November 2017: Oral and Maxillofacial Surgery Clinics of North America
https://www.readbyqxmd.com/read/28975191/extracapsular-dissection-vs-superficial-parotidectomy-of-benign-parotid-lesions-surgical-outcomes-and-cost-effectiveness-analysis
#11
Masanari G Kato, Evren Erkul, Shaun A Nguyen, Terry A Day, Joshua D Hornig, Eric J Lentsch, M Boyd Gillespie
Importance: The clinical implications of extracapsular dissection over superficial parotidectomy are controversial and limited in data on cost-effectiveness. Objective: To compare extracapsular dissection with superficial parotidectomy for benign parotid tumors with respect to surgical outcomes and cost-effectiveness. Design, Setting, and Participants: This was a retrospective medical record review and cost-effectiveness analysis performed from August 2012 to November 2015 at a tertiary care institution...
November 1, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28955679/polymorphous-low-grade-adenocarcinoma-of-the-parotid-in-a-teenager
#12
Divya Khosla, Shalini Verma, Nitin Gupta, Rajpal-S Punia, Gurbir Kaur, Awadhesh-K Pandey, Kislay Dimri
INTRODUCTION: Polymorphous low grade adenocarcinoma (PLGA) is a rare salivary gland neoplasm with an indolent course. It occurs primarily in the minor salivary glands but can rarely occur in the major salivary glands. It usually occurs in the fifth to seventh decades of life with female preponderance. CASE REPORT: A 16-year-old male presented with recurrent painless swelling in the right preauricular region and with a history of surgical intervention at the same site in the past...
September 2017: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28932028/cytological-spectrum-of-salivary-gland-lesions-and-their-correlation-with-epidemiological-parameters
#13
Vaneet Kaur Sandhu, Upender Sharma, Navtej Singh, Arun Puri
BACKGROUND: The role fine-needle aspiration (FNA) in the diagnosis of salivary gland lesions has evolved over the years. Although clinical and radiological parameters help to narrow the differential diagnosis the tissue diagnosis still remains the gold standard. MATERIALS AND METHODS: This study is from January 2013 to December 2015 in our Department of Pathology where 170 salivary gland lesions were aspirated. The aim of the present study was to analyze adequacy rate in relation to the size of lesion and to evaluate varied cytological spectrum of salivary gland lesions with emphasis on differential diagnosis and to correlate cytological diagnosis with age, gender and anatomical site...
May 2017: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/28913321/mixed-tumor-in-deep-lobe-and-versatility-of-acellular-dermal-matrix
#14
Jin Hwan Byun, Jung Soo Lim, Hye Kyung Lee
Frey's syndrome and infra-auricular depressed deformities are the ones of the most common complications that can occur after total parotidectomy. We report 1 case of pleomorphic adenoma occurred in the deep lobe that obtained good results from using acellular dermal matrix (ADM) after total parotidectomy. A 24-year-old man visited the hospital with oval shape mass in right mandibular angle which of 4 cm in size was found in the deep lobe of right parotid gland from Magnetic resonance imaging scanning and a pleomorphic adenoma was suspected...
June 2017: Arch Craniofac Surg
https://www.readbyqxmd.com/read/28900471/metastasizing-pleomorphic-adenoma-of-the-parotid-gland
#15
Javier Soteldo, Nathasha Aranaga
Salivary gland tumours are estimated to represent approximately 3% of all head and neck tumours. About 70-80% of these neoplasms occur in the major salivary glands, with the parotid gland being the most commonly affected site. The metastasizing pleomorphic adenoma (MPA) has histological characteristics of pleomorphic adenoma, but it has the capacity to generate local recurrences and distant metastases (mainly bones, lungs, and lymph nodes). Despite the fact that some authors consider it to be a benign neoplasia, the 2015 World Health Organisation (WHO) classification of head and neck tumours considers it to be malignant...
2017: Ecancermedicalscience
https://www.readbyqxmd.com/read/28878649/a-symptomatic-case-of-adenomatous-ductal-proliferation-hyperplasia-with-a-large-cystic-lesion
#16
Nobuhiko Seki, Norikazu Yamazaki, Tatsuru Ikeda, Hiroshi Hadara, Tetsuo Himi
Adenomatous ductal proliferation/hyperplasia (ADP/H) of the salivary gland, a rare asymptomatic nonneoplastic lesion that histopathologically resembles basal cell adenoma, is typically incidentally identified in resected specimens of other salivary diseases such as tumors and chronic sialadenitis. A 70-year-old male was referred to our hospital with a 9-month history of continuous swelling in the left parotid region. A physical examination revealed a soft mass in the left parotid gland, which was identified as a cystic mass by computed tomography...
May 2017: Case Reports in Oncology
https://www.readbyqxmd.com/read/28863883/clinicopathologic-and-surgical-study-of-pleomorphic-adenoma-of-the-parotid-gland-analysis-of-risk-factors-for-recurrence-and-facial-nerve-dysfunction
#17
Carlos A Espinosa, Álvaro Fernández-Valle, Paloma Lequerica-Fernández, Lucas de Villalaín, Juan Carlos de Vicente
PURPOSE: To determine whether clinicopathologic or surgical features are risk factors for recurrence and facial nerve dysfunction in pleomorphic adenoma (PA) of the parotid gland. PATIENTS AND METHODS: The records of 198 patients surgically treated for a PA of the parotid gland from 1999 through 2013 were retrospectively reviewed to identify patients who developed a tumor recurrence. The Fisher exact test and Mann-Whitney U test were used to analyze patient characteristics between recurrent and non-recurrent PAs...
August 3, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28844507/accuracy-of-fnac-and-ct-in-the-differentiation-of-benign-and-malignant-parotid-tumours-in-a-case-series
#18
Marina A Gavín-Clavero, Tomás Usón-Bouthelier, Úrsula M Jariod-Ferrer, Arancha Fernández-Larrañaga, Bianca Pantilie, Fernando Lobera-Molina, M Victoria Simón-Sanz, Bartolomé Nadal Cristóbal
INTRODUCTION: Parotid tumours, in addition to the wide variety of types, are histologically complex. Differentiating between benign and malignant tumours in preoperative diagnosis is important in deciding the type of surgery required. Fine needle aspiration cytology (FNAC) is a simple, quick, low-cost, low-invasive and well-tolerated tool used in the preoperative diagnosis of these tumours. MATERIAL AND METHODS: we calculated the sensitivity, specificity, predictive positive value (PPV) and negative predictive value (NPV) of FNAC and computed tomography (CT) in the differentiation of benign and malignant parotid tumours operated between 2010 to 2014 in the oral and maxillofacial surgery department of the University Hospital Miguel Servet...
August 24, 2017: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/28840842/chemokine-and-chemokine-receptor-patterns-in-patients-with-benign-and-malignant-salivary-gland-tumors-a-distinct-role-for-ccr7
#19
Mohammad Reza Haghshenas, Mohammad Javad Ashraf, Bijan Khademi, Abbas Ghaderi, Nasrollah Erfani, Mahboobeh Razmkhah
To explore the molecular mechanisms involved in pathophysiology of malignant and benign salivary gland tumors (SGTs), we investigated main tumor-inducing chemokines and chemokine receptors, CXCL12/CXCR4/ACKR3 (CXCR7), CXCR3/CXCL10, CCR5/CCL5, CCL21/CCR7, CCL2, CCR4, CXCR5, CCR6, and CXCL8 in tumor tissues. Parotid tissues were obtained from 30 patients with malignant and benign SGTs. Quantitative real-time polymerase chain reaction (qRT-PCR) was employed to determine the mRNA expression pattern of the mentioned chemokines/chemokine receptors and immunohistochemistry (IHC) was performed to verify the expression of CCR7...
March 1, 2017: European Cytokine Network
https://www.readbyqxmd.com/read/28739497/salivary-gland-epithelial-neoplasms-in-pediatric-population-a-single-institute-experience-with-a-focus-on-the-histologic-spectrum-and-clinical-outcome
#20
Bin Xu, Amandeep Aneja, Ronald Ghossein, Nora Katabi
Salivary gland epithelial neoplasms are rare in children and adolescents, with only a handful of large series having been published. A retrospective study was conducted for 57 cases in patients 20 years or younger. The tumors were located in the parotid (n=36), submandibular gland (n=7), and minor salivary glands (n=14). Nineteen (33%) tumors were pleomorphic adenoma, whereas the remaining (67%) were malignant. The histologic types of carcinomas were mucoepidermoid carcinoma (MEC, n=19, 33%), acinic cell carcinoma (n=7, 12%), adenoid cystic carcinoma (n=6, 11%), secretory carcinoma (mammary analogue) (SC, n=4, 7%), and myoepithelial carcinoma (n=2, 4%)...
September 2017: Human Pathology
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