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parotid adenoma

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https://www.readbyqxmd.com/read/29691554/-retrospective-analysis-of-896-cases-of-parotid-gland-tumor
#1
Zhi-Guo Zhao, Dan Gao, Jin Wang, Li-Ping Zhang
PURPOSE: To review the clinical data of patients undergoing operation, in order to summarize the incidence, proportion, clinical examination and diagnostic methods of parotid tumors. METHODS: Eight hundred and ninty-six cases of parotid gland tumors were collected from 2008 January to 2015 July from department of oral and maxillofacial surgery in Shengjing Hospital of China Medical University. A retrospective study of the clinical data was carried out, including age, gender, tumor location, diagnostic methods and pathological results...
December 2017: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/29689463/submandibular-gland-pleomorphic-adenoma-histopathological-capsular-characteristics-and-correlation-with-the-surgical-outcome
#2
Konstantinos Mantsopoulos, Miguel Goncalves, Michael Koch, Heinrich Iro, Abbas Agaimy
Pleomorphic adenoma (PA) of the submandibular gland is known to have a very low recurrence rate. The aim of this study was to investigate the histopathological and capsular characteristics of submandibular gland PA, looking for any differences between submandibular PA and the reported data for PA of the parotid gland as possible explanation for its low recurrence rate. We reviewed 72 submandibular gland PAs resected at our center between 2000 and 2016. Patient age ranged from 14 to 77 years (mean, 47.2). At least follow (range, 12 to 170 months; mean, 82), none of the 72 patients developed a local recurrence...
April 18, 2018: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/29667889/journal-club-the-warthin-tumor-score-a-simple-and-reliable-method-to-distinguish-warthin-tumors-from-pleomorphic-adenomas-and-carcinomas
#3
Chih-Wei Wang, Yueng-Hsiang Chu, Deng-Yiv Chiu, Nieh Shin, Hsian-He Hsu, Jih-Chin Lee, Chun-Jung Juan
OBJECTIVE: The objective of this article is to propose a Warthin tumor (WT) score to distinguish WTs from other parotid tumors. MATERIALS AND METHODS: The study included 78 patients with 92 histologically proven parotid tumors, including 42 WTs, 30 pleomorphic adenomas (PMAs), and 20 carcinomas. Echo-planar DW images were acquired. The WT score, which comprised the mean apparent diffusion coefficient (ADCM ) and the SD of the ADC (ADCSD ) of tumors, patient age, and patient sex, was used to predict WTs...
April 18, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29659384/tumor-induced-osteomalacia-caused-by-a-parotid-basal-cell-adenoma-detected-by-68ga-dotanoc-pet-ct
#4
Qiao He, Zeqing Xu, Bing Zhang, Wanming Hu, Xiangsong Zhang
Tumor-induced osteomalacia is a rare paraneoplastic syndrome, usually caused by small benign mesenchymal tumors. The tumors most arise within the extremities, whereas occurrence within the parotid gland is quite rare. A 54-year-old woman who presented with bone pain and muscle weakness for 2 years was clinically suspected of having tumor-induced osteomalacia. A Ga-DOTANOC PET/CT was performed for localization of the causative tumor. The images demonstrated intense radiotracer accumulation in a soft tissue nodule in deep lobe of the right parotid gland...
April 13, 2018: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29656683/clinicopathologic-analysis-of-2736-salivary-gland-cases-over-a-11-year-period-in-southwest-china
#5
S Y Shen, W H Wang, R Liang, G Q Pan, Y M Qian
OBJECTIVE: To investigate the epidemiological and clinicopathological characteristics of salivary gland tumors in southwest China in order to provide data for clinical diagnosis and other similar research. METHODS: Between March 2007 and December 2017, 2736 patients with salivary gland tumors were recruited, the clinical and pathological data were retrospectively analyzed. RESULTS: A total of 2736 patients had a ratio of males to females of about 1...
April 14, 2018: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29651432/oxidative-stress-markers-patients-with-parotid-gland-tumors-a-pilot-study
#6
Pawel Sowa, Maciej Misiolek, Bartlomiej Pasinski, Grzegorz Bartosz, Miroslaw Soszynski, Monika Adamczyk-Sowa, Izabela Sadowska-Bartosz
Salivary gland tumors account for 3-6% of tumors of the head and neck. About 80% of salivary gland tumors occur in parotid glands. Oxidative stress (OS) is implicated in the origin, development, and whole-body effects of various tumors. There are no data on the occurrence of OS in the parotid gland tumors. The aim of this study was to ascertain if whole-body OS accompanies parotid gland tumors, based first of all on oxidative modifications of blood serum proteins and other markers of OS in the serum of the patients...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29599620/vanishing-parotid-tumors-on-mr-imaging
#7
Eiji Matsusue, Yoshio Fujihara, Eiken Matsuda, Yusuke Tokuyasu, Shu Nakamoto, Kazuhiko Nakamura, Toshihide Ogawa
Background: Of all parotid gland tumors, only oncocytoma has been reported to appear isointense to the parotid gland, namely vanishing, on fat-saturated T2 and T1 postcontrast gadolinium-enhanced magnetic resonance imaging (MRI). The purpose of this study was to evaluate vanishing of parotid tumors on conventional MRI with and/or without postcontrast gadolinium-enhancement and on diffusion weighted imaging (DWI). Methods: In 8 of 51 patients, ten parotid gland tumors had homogeneously enhanced lesions and were retrospectively analysed...
March 2018: Yonago Acta Medica
https://www.readbyqxmd.com/read/29549722/serum-levels-of-selected-adipocytokines-in-benign-and-malignant-parotid-gland-tumor-patients
#8
Pawel Sowa, Maciej Misiolek, Boguslawa Orecka, Eugeniusz Czecior, Monika Adamczyk-Sowa
OBJECTIVES: The aim of this study was to evaluate serum levels of adiponectin, leptin, visfatin and IL-6 in patients with pleomorphic adenoma, Warthin's tumor and acinic cell carcinoma of the parotid gland. MATERIALS AND METHODS: Venous blood samples were collected from 30 patients with pleomorphic adenoma, 21 patients with Warthin's tumor and 8 patients with acinic cell carcinoma. Serum adiponectin, leptin, visfatin, IL-6 and CRP concentrations were determined...
March 14, 2018: Cytokine
https://www.readbyqxmd.com/read/29549132/a-huge-pleomorphic-adenoma-of-the-submandibular-salivary-gland
#9
Ashutosh Rai, Sushil Sharma, Prabhat Shrivastava, Mangal Singh
The most common tumour of salivary gland is pleomorphic adenoma (PA). They are benign, painless, can grow into big tumours but usually do not affect nerves or lymph nodes. PA most commonly occurs in the parotid gland but it may involve submandibular, lingual and minor salivary glands also. They can attain giant proportions and weigh several kilograms. We report a giant PA arising in the submandibular gland and treated by complete surgical excision without any complication. A female patient presented with a tumour in the submandibular region and front of neck with a history of more than 18 years...
March 16, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29530428/partial-parotidectomy-under-local-anesthesia-for-benign-parotid-tumors-an-experience-of-50-cases
#10
Siu Hong Cheung, Wai Yin Wilson Kwan, Kwan Pok Tsui, Tam Lin Chow
PURPOSE: Benign parotid tumors are adequately treated with partial parotidectomy, which is often performed under general anesthesia (GA). We have reported our preliminary results on the feasibility to perform parotidectomy under local anesthesia (LA). We hereby present our accumulated experience of partial parotidectomy under LA to further consolidate its feasibility, efficacy and safety in a larger series. MATERIALS AND METHODS: Case series review was carried out using our own center patients' database...
March 2, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29526342/current-thinking-about-the-management-of-recurrent-pleomorphic-adenoma-of-the-parotid-a-structured-review
#11
REVIEW
A Kanatas, M W S Ho, T Mücke
Pleomorphic adenoma is the most common tumour of the parotid gland, and can recur after excision. Recurrent pleomorphic adenoma can be a challenge to treat, and has variable outcomes. The aim of this review was to summarise current thinking in its management, which may be helpful to clinical teams and could improve patients' health-related quality of life. We searched several online databases using the key terms pleomorphic adenoma, recurrent pleomorphic adenoma, parotid gland tumours, parotid surgery, radiotherapy and parotid pleomorphic adenoma, and parotid surgery outcomes...
March 8, 2018: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/29521047/expression-of-vegf%C3%A2-%C3%A2-%C3%A2-b-vegfr1-vegfr2-and-cd34-in-benign-and-malignant-tumors-of-parotid-glands
#12
Katarzyna J Błochowiak, Jerzy Sokalski, Magdalena B Bodnar, Dorota Trzybulska, Andrzej K Marszałek, Henryk Witmanowski
BACKGROUND: Vascular endothelial growth factor (VEGF) is an angiogenic factor and could be involved in the pathogenesis of salivary gland tumors. VEGF exerts its biological function by binding to its receptors, VEGFR1 and VEGFR2. An alternative splice variant of VEGF (VEGFxxxb) is an anti-angiogenic factor. Binding VEGF165b with VEGFR2 results in an impaired angiogenic response. The imbalance of VEGFxxx and VEGFxxxb isoforms can underpin pathological angiogenesis. OBJECTIVES: The purpose of this study was to evaluate and compare the expression of VEGF165b, VEGFR1, VEGFR2, and CD34 in benign and malignant parotid gland tumors and to explore the possible correlations between their expression and clinicopathological features of tumors...
January 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29494398/rank-and-rank-ligand-expression-in-parotid-gland-carcinomas
#13
Alessandro Franchi, Cecilia Taverna, Antonella Simoni, Monica Pepi, Giuditta Mannelli, Martina Fasolati, Oreste Gallo
Recently, it has been reported that deregulation of the receptor activator of NFkB ligand (RANKL)/RANK signaling axis results in salivary gland tumor development in a mouse transgenic model. The aim of this study was to ascertain RANKL and RANK protein expression in a series of primary parotid gland carcinomas and to correlate it with clinicopathologic parameters. Formalin-fixed paraffin-embedded tumor samples from 46 consecutive cases of parotid gland carcinoma were selected for this study. For comparison, we examined a group of 40 randomly chosen parotid gland adenomas, including 20 pleomorphic adenomas, 10 myoepitheliomas, and 10 Warthin tumors...
February 28, 2018: Applied Immunohistochemistry & Molecular Morphology: AIMM
https://www.readbyqxmd.com/read/29493727/syncope-caused-by-a-pleomorphic-adenoma-case-report-and-literature-review
#14
Anas Minkara, Reena Dhanda-Patil, Yash Patil
Pleomorphic adenomas are considered the most common salivary gland tumors, although they rarely occur in the parapharyngeal space. To the best of our knowledge, this is the first case report of a parapharyngeal parotid pleomorphic adenoma causing syncope. A 57-year-old man was admitted for left-sided blurred vision, left-sided weakness, dysarthria, lightheadedness, and syncope. Upon his admission, an electrocardiogram showed sinus bradycardia, and computed tomography of the neck with contrast showed a large parapharyngeal mass involving the prestyloid compartment, leading to compression of blood flow through the internal carotid artery...
January 2018: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29459898/parotid-quadrantectomy-is-a-safe-management-for-localized-pleomorphic-adenoma
#15
Osama Hussein, Khaled Abdel Wahab, Omar Hamdy, Mohammad Arafa, Emad-Eldeen Hamed, Shady Awny, Sameh Roshdy, Adel Denewer, Mahmoud Mosbah
Aim: Pleomorphic adenoma is the most common benign tumor of the parotid gland and is classically treated with superficial or total parotidectomy. Less radical surgeries have been proposed to minimize the risk of facial nerve injury. The oncological safety of these procedures remains controversial. We conducted this study to evaluate the safety of superficial hemi-lobectomy (quadrantectomy). Patients and methods: Retrospective analysis was conducted on the paraffin sections of archived superficial parotidectomy specimens from 11 male and 6 female patients (median age 33 years)...
2018: Frontiers in Surgery
https://www.readbyqxmd.com/read/29434491/usefulness-of-a-novel-ultrasonographic-classification-based-on-anechoic-area-patterns-for-differentiating-warthin-tumors-from-pleomorphic-adenomas-of-the-parotid-gland
#16
Eriko Matsuda, Takahiro Fukuhara, Ryohei Donishi, Katsuyuki Kawamoto, Yasuaki Hirooka, Hiromi Takeuchi
Background: Ultrasonographic homogeneity is an important differential finding between Warthin tumor and pleomorphic adenoma, two types of benign parotid gland tumors, with the former likely to be heterogeneous and the latter homogeneous. However, differences in the performance of ultrasound machines or the homogeneity cut-off level affect the judgment of ultrasonographic homogeneity. Therefore, in this study, we adopted a novel system for classifying the composition of tumors via ultrasonography, using anechoic area as a substitute for differences in homogeneity to differentiate between Warthin tumors and pleomorphic adenomas...
December 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/29430614/non-enhanced-mri-in-combination-with-color-doppler-flow-imaging-for-improving-diagnostic-accuracy-of-parotid-gland-lesions
#17
Wei Zhang, Zhichao Zuo, Ningbin Luo, Lianfeng Liu, Guanqiao Jin, Junjie Liu, Danke Su
PURPOSE: To determine the value of non-enhanced MRI in combination with color Doppler flow imaging (CDFI) for differentiating malignant parotid tumors from benign ones. METHODS: This retrospective study analyzed 51 parotid gland lesions (39 benign and 12 malignant) in 51 patients who underwent preoperative CDFI as well as non-enhanced MRI including T1 -weighted, T2 -weighted, and diffusion-weighted imaging (DWI). Degrees of intratumor vascularity were categorized into four grades basing on CDFI findings...
February 12, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29425058/a-multiparametric-analysis-combining-dce-mri-and-ivim-derived-parameters-to-improve-differentiation-of-parotid-tumors-a-pilot-study
#18
Francesca Patella, Giuseppe Franceschelli, Mario Petrillo, Mario Sansone, Roberta Fusco, Filippo Pesapane, Giovanni Pompili, Anna Maria Ierardi, Alberto Maria Saibene, Laura Moneghini, Federico Biglioli, Gianpaolo Carrafiello
AIM: To evaluate dynamic contrast-enhanced (DCE)-MRI and diffusion weighted (DW)-MRI diagnostic value to differentiate Warthin tumors (WT) by pleomorphic adenomas (PA). MATERIALS & METHODS: Seven WT and seven PA were examined. DCE- and  DW-MRI parameters were extracted from volumes of interest; volume of interest-based averages and standard deviations were calculated. Statistical analysis included: linear discriminant analysis, receiver operating characteristic curves, sensitivity and specificity...
February 9, 2018: Future Oncology
https://www.readbyqxmd.com/read/29403173/fine-needle-aspiration-cytology-of-basal-cell-adenoma-of-parotid-simulating-adenoid-cystic-carcinoma
#19
Subrata Pal, Palash Kr Mondal, Abhishek Sharma, Mrinal Sikder
Basal cell adenoma is a rare type of monomorphic salivary adenoma most commonly involving the parotid gland. Cytology of basal cell adenoma closely mimics many other benign and malignant basaloid neoplasms. Cytological features of membranous basal cell adenoma simulate adenoid cystic carcinoma in fine needle aspiration cytology (FNAC) smears. Here, we are presenting a rare case of cytodiagnosis of membranous basal cell adenoma of parotid gland in an elderly lady, which mimicked adenoid cystic carcinoma on FNAC...
January 2018: Journal of Cytology
https://www.readbyqxmd.com/read/29301803/extramedullary-plasmacytoma-rare-neoplasm-of-parotid-gland
#20
Sehrish Abrar, Nasir Ali, Bilal Mazhar Qureshi, Ahmed Nadeem Abbasi
A 45-year-old man presented with left-sided facial swelling. Initial excisional biopsy was done somewhere else without prior imaging and it came out to be pleomorphic adenoma; local imaging after biopsy showed mass over the left parotid gland with ipsilateral lymphadenopathy. On examination, there was a well-circumscribed mass with signs of left facial nerve palsy. He underwent left radical parotidectomy with ipsilateral modified radical neck dissection, and per operatively, it came out to be neoplastic lesion...
January 4, 2018: BMJ Case Reports
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