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https://www.readbyqxmd.com/read/28108853/brain-metastasis-of-carcinoma-ex-pleomorphic-adenoma-of-the-parotid-gland-case-report-and-review-of-the-literature
#1
Ruth Lau, Alejandro Fernández-Coello, Noemí Vidal-Sarró, Dennis Céspedes, Angels Camins, Miren Taberna, Andreu Gabarrós
We present an extremely infrequent case of brain metastasis of a parotid tumor. To our knowledge, this is the second case reported of a brain metastasis of a malignant parotid tumor, carcinoma ex pleomorphic adenoma. Pleomorphic adenoma represents 60% of tumors of the parotid gland, and although it is a benign tumor, it can transform into carcinoma ex pleomorphic adenoma in 5% of cases, one of the most aggressive neoplasms of the salivary glands. We want to note the need for an accurate diagnostic. Thanks to aggressive surgical management, our patient survived more than 1½ years...
January 20, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28076460/the-accuracy-of-fine-needle-aspiration-cytology-for-diagnosis-of-parotid-gland-masses-a-clinicopathological-study-of-114-patients
#2
Jens Kristjan Gudmundsson, Aida Ajan, Jahan Abtahi
Objective: Fine-needle aspiration cytology is a valuable method for preoperative assessment of head and neck tumors. However, its accuracy in detection of salivary gland masses is controversial compared with other methods. The aim of this work was to evaluate the effectiveness and accuracy of fine-needle aspiration cytology (FNAC) in the diagnosis of parotid gland masses. Material and Methods: Over a 10-year period, 126 parotid gland masses were resected. Retrospective chart reviews of 114 patients were performed...
November 2016: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/27997063/investigation-of-arguments-against-properly-indicated-extracapsular-dissection-in-the-parotid-gland
#3
Konstantinos Mantsopoulos, Claudia Scherl, Heinrich Iro
BACKGROUND: The ideal extent of surgical intervention for benign parotid tumors remains a matter of controversy. The purpose of this study was to examine the existing arguments against extracapsular dissection and present our experience over the last 16 years. METHODS: A retrospective evaluation was carried out on the records of all patients who underwent extracapsular dissection for benign parotid tumors at a tertiary referral center between 2000 and 2015. RESULTS: A total of 1359 cases were included in the study...
December 20, 2016: Head & Neck
https://www.readbyqxmd.com/read/27976552/parotidectomy-outcomes-diagnosis-and-complications-on-pediatric-patients-twelve-years-of-experiences-in-a-tertiary-care-center
#4
Oğuz Kuşcu, Bahar Kayahan, Övsen Önay, Rıza Önder Günaydın, Mehmet Umut Akyol
The aim of this study is to evaluate parotid masses management in pediatric population. From June 2002 to December 2014, 13 patients under the age of 18 with parotid tumors were treated via surgery at Hacettepe University Department of Otorhinolaryngology. Information on patients' demographics, clinical and histopathologic tumor characteristics and treatment modalities with results was obtained from medical records, retrospectively. The age was ranging between 8-17 years. Ten (76.9%) patients had benign tumors and 8 (61...
2016: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/27925646/real-time-sonoelastography-of-parotid-gland-tumors
#5
Namık Kemal Altinbas, Ezgi Gundogdu Anamurluoglu, Ibrahim Ilker Oz, Cemal Yuce, Cemil Yagci, Evren Ustuner, Serdar Akyar
OBJECTIVES: We sought to determine the performance of real-time sonoelastography in the differential diagnosis of parotid gland tumors. METHODS: Between April, 2014, and June, 2015, 54 parotid gland masses were examined by ultrasound and strain sonoelastography in 46 patients. Real-time sonoelastography using the elasticity score (E-index), which gives an absolute value between 0 (softest) and 6 (hardest), was performed. Demographic characteristics, histopathologic examination, and difference in elasticity scores between benign and malignant masses were evaluated...
January 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/27874161/diffusion-weighted-magnetic-resonance-imaging-in-the-diagnosis-of-parotid-masses-preliminary-results
#6
Zeynel Yologlu, Hasan Aydin, Nalan A Alp, Bilgin K Aribas, Volkan Kizilgoz, Kemal Arda
To demonstrate the diagnostic potentials of MRI, diffusion weighted imaging (DWI), and apparent diffusion coefficient (ADC) mapping in the detection of parotid masses correlated to the histopathological results. Methods: Study design was retrospective. Fifteen patients with parotid gland masses were included as the study group and contralateral normal parotis glands of same patients were taken as the control group. Patients with bilateral parotid gland tumors were excluded, 7 right-sided and 8 left-sided parotid masses were included in the research...
December 2016: Saudi Medical Journal
https://www.readbyqxmd.com/read/27845594/diffusion-weighted-mri-for-differentiation-between-sialadenitis-and-pleomorphic-adenoma
#7
Guilherme T C Terra, Jefferson X D Oliveira, Adalsa Hernandez, Silvia V Lourenço, Emiko S Arita, Arthur R G Cortes
OBJECTIVES: The aim of this study was to compare apparent diffusion coefficient (ADC) values from diffusion-weighted MRI (DWI) among normal salivary glands, cases with sialadenitis and cases with pleomorphic adenoma of major salivary glands. METHODS: 22 patients (totalling 44 major salivary glands) diagnosed with either unilateral sialadenitis (on either parotid or submandibular gland) or parotid gland pleomorphic adenoma were selected. Contralateral non-affected glands (normal) were also analyzed...
January 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/27793123/invasive-myoepithelial-carcinoma-ex-pleomorphic-adenoma-of-the-major-salivary-gland-two-case-reports
#8
Takahiro Wakasaki, Marie Kubota, Yutaka Nakashima, Eri Tomonobe, Takenao Mihara, Junichi Fukushima
BACKGROUND: Myoepithelial carcinoma (MEC) is a rare salivary gland tumor. Its long-term prognosis remains unknown because of the paucity of reported cases with long-term follow-up. Although some case series exist, the clinical features of MEC vary considerably depending on the site of origin. Therefore, accumulation of these rare cases is important. CASE PRESENTATION: Case 1: An 89-year-old man presented with a 10-year history of a mass originating from the right parotid gland and involving the neck...
October 28, 2016: BMC Cancer
https://www.readbyqxmd.com/read/27769738/salivary-gland-tumours-in-a-northern-chinese-population-a-50-year-retrospective-study-of-7190-cases
#9
M Gao, Y Hao, M X Huang, D Q Ma, Y Chen, H Y Luo, Y Gao, Z Q Cao, X Peng, G Y Yu
The aims of this study were to investigate the epidemiological and clinical characteristics of epithelial salivary gland tumours in a northern Chinese population and to evaluate the current TNM classification system. A demographic and descriptive analysis of 7190 epithelial salivary gland tumours was performed. There were 4654 benign tumours and 2536 malignant tumours. The percentage of tumours located in the parotid, submandibular, sublingual, and minor salivary glands was 62.66%, 9.92%, 2.57%, and 24.85%, respectively; 22...
October 18, 2016: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27755404/carcinoma-ex-pleomorphic-adenoma-of-the-tongue-difficulty-in-diagnosis-between-metastasis-of-breast-cancer-and-salivary-tumor
#10
Yuki Sakamoto, Shuichi Fujita, Masaki Adachi, Hiroshi Sakamoto, Tomofumi Naruse, Souichi Yanamoto, Toru Ikeda, Masahiro Umeda
Carcinoma ex pleomorphic adenoma (CEPA) is a carcinoma that shows histologic evidence of arising in or from a benign pleomorphic adenoma. Carcinoma ex pleomorphic adenoma often occurs in parotid glands, but is extremely rarely in the tongue. A 53-year-old Japanese woman was referred to the Department of Oral and Maxillofacial Surgery, Nagasaki University Hospital, because of tumor of the right dorsum tongue. She had a history of surgery of breast cancer (invasive ductal carcinoma) and it was disseminated to the lung and bone...
October 14, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27755360/hemifacial-spasm-secondary-to-parotid-pleomorphic-adenoma-with-stylomastoid-foramen-extension
#11
Eliot J Martin, Matthew L Carlson, Eric J Moore, Ryan S Jackson
OBJECTIVE: To report hemifacial spasm (HFS) as a rare presenting symptom of a benign parotid neoplasm involving the stylomastoid foramen. METHODS: Case report with literature review. RESULTS: An 18-year-old woman presented with a 1-year history of a progressively enlarging right infra-auricular mass with new onset ipsilateral severe HFS. Clinical vetting unveiled a palpable 2 cm, firm, minimally mobile mass medial to the angle of the mandible...
January 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/27704717/extracapsular-dissection-versus-superficial-parotidectomy-in-benign-parotid-gland-tumors-the-vienna-medical-school-experience
#12
Lorenz Kadletz, Stefan Grasl, Matthäus C Grasl, Christos Perisanidis, Boban M Erovic
BACKGROUND: The purpose of this study was to evaluate the clinical outcome in patients with benign parotid gland tumors after extracapsular dissection or superficial parotidectomy (SP). METHODS: Eight hundred ninety-four patients with primary pleomorphic adenoma or Warthin's tumor were included from this study. Type and length of surgery, tumor size, resection margins, and complication rates were assessed. RESULTS: Three hundred ninety-five (44...
October 5, 2016: Head & Neck
https://www.readbyqxmd.com/read/27684860/pedunculated-carcinoma-ex-pleomorphic-adenoma-of-the-nasal-cavity-a-unique-case-report
#13
Po-Wu Liao, Yen-Lin Chen, Jeng-Wen Chen
BACKGROUND: A carcinoma ex pleomorphic adenoma (CXPA) is an epithelial malignancy arising in or from a benign pleomorphic salivary adenoma. The parotid gland is the most common location of CXPAs. Minor salivary gland CXPAs of the nasal cavity are exceedingly rare, with only 6 documented in the literature. METHODS AND RESULT: We present a 7th case: an unusual pedunculated intranasal CXPA, which had a favorable outcome after a wide endoscopic excision and the longest follow-up period reported to date...
September 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27672466/leiomyosarcoma-ex-pleomorphic-adenoma-of-the-parotid-gland-a-case-report-and-literature-review
#14
Michael Coulter, Jingxuan Liu, Mark Marzouk
There is only one previously reported incident in the English literature of sarcoma ex pleomorphic adenoma of the parotid and there are only 8 cases of primary parotid leiomyosarcoma. In our case, a 79-year-old female patient presented to our care with left preauricular pain, swelling, and facial weakness. After CT imaging, she underwent left total parotidectomy. A spindle cell lesion was identified intraoperatively and the facial nerve was sacrificed. Subsequent analysis of the lesion yielded a diagnosis of leiomyosarcoma ex pleomorphic adenoma...
2016: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/27663220/parapharyngeal-space-primary-tumours
#15
Gianluigi Grilli, Vanessa Suarez, María Gabriela Muñoz, María Costales, José Luis Llorente
INTRODUCTION AND OBJECTIVES: The aim of this study is to present our experience with the diagnostic and therapeutic approaches for parapharyngeal space tumours. PATIENTS AND METHOD: This study is a retrospective review of 90 patients diagnosed with tumours of the parapharyngeal space and treated surgically between 1984 and 2015. Patients whose tumours were not primary but invaded the parapharyngeal space expanding from another region, tumours originating in the deep lobe of the parotid gland and head and neck metastasis were excluded from this study...
September 20, 2016: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/27636248/characterization-of-parotid-tumors-with-dynamic-susceptibility-contrast-perfusion-weighted-magnetic-resonance-imaging-and-diffusion-weighted-mr-imaging
#16
Ahmed Abdel Khalek Abdel Razek, Sieza Samir, Germeen Albair Ashmalla
PURPOSE: To characterize parotid tumors with dynamic susceptibility contrast perfusion-weighted magnetic resonance (MR) imaging and diffusion-weighted MR imaging. MATERIAL AND METHODS: Prospective study was conducted upon 48 consecutive patients (27 men, 21 women; aged 15-75 years; mean, 45 years) with parotid tumors that underwent dynamic susceptibility contrast perfusion-weighted MR imaging was performed after bolus injection of gadopentate dimeglumine and diffusion-weighted MR imaging...
September 16, 2016: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/27627686/parotid-malignancies-are-not-homogenous-in-terms-of-their-presentation-on-dynamic-mri-a-preliminary-report
#17
Bogusław Mikaszewski, Karolina Markiet, Aneta Smugała, Dominik Stodulski, Edyta Szurowska, Czesław Stankiewicz
CONCLUSION: At least two groups of parotid malignancies exist, including one whose parameters of dynamic MRI closely resemble those of pleomorphic adenomas. Also tumors with long time to peak enhancement after administration of a contrast agent (Tpeak) and low washout rate (WR) should be considered malignant, especially single masses with concomitant lymphadenopathy located within the deep parotid lobe. OBJECTIVE: To verify if malignant tumors of the parotid are homogeneous in terms of parameters of preoperative dynamic MRI: Tpeak and WR...
September 14, 2016: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/27623207/high-grade-transformation-of-salivary-gland-acinic-cell-carcinoma-with-emphasis-on-histological-diagnosis-and-clinical-implications
#18
Danielle Bury, Mugtaba Dafalla, Shabada Ahmed, Henrik Hellquist
Acinic cell carcinoma (ACC) is commonly thought of as a low grade malignant salivary neoplasm, and possibly has the best prognosis of all salivary malignancies with a 10-year survival of almost 90%. High grade transformation (HGT) in these tumours is a relatively rare event but is increasingly being reported. HGT (formerly referred to as dedifferentiation) in acinic cell carcinoma has shown to drastically reduce the survival rates and its recognition is imperative as more aggressive clinical management is needed...
November 2016: Pathology, Research and Practice
https://www.readbyqxmd.com/read/27618707/autoimmune-glial-fibrillary-acidic-protein-astrocytopathy-a-novel-meningoencephalomyelitis
#19
Boyan Fang, Andrew McKeon, Shannon R Hinson, Thomas J Kryzer, Sean J Pittock, Allen J Aksamit, Vanda A Lennon
Importance: A novel astrocytic autoantibody has been identified as a biomarker of a relapsing autoimmune meningoencephalomyelitis that is immunotherapy responsive. Seropositivity distinguishes autoimmune glial fibrillary acidic protein (GFAP) meningoencephalomyelitis from disorders commonly considered in the differential diagnosis. Objective: To describe a novel IgG autoantibody found in serum or cerebrospinal fluid that is specific for a cytosolic intermediate filament protein of astrocytes...
September 12, 2016: JAMA Neurology
https://www.readbyqxmd.com/read/27601813/role-of-fine-needle-aspiration-cytology-in-the-diagnosis-of-major-salivary-gland-tumors-a-study-with-histological-and-clinical-correlation
#20
Archana Shetty, V Geethamani
INTRODUCTION: Neoplastic lesions of salivary glands present an interesting subject because of their histologic diversification. Complex features exhibited by them have aroused considerable speculations concerning their histogenesis and continues to hold the interest of clinicians and pathologists. Major salivary glands are superficial and have easy accessibility for fine-needle aspiration cytology (FNAC). These glands are generally not subjected to incisional or core needle biopsy, because of the possible risks of fistula formation and tumor seedling...
May 2016: Journal of Oral and Maxillofacial Pathology: JOMFP
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