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Type B dissection

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https://www.readbyqxmd.com/read/29346780/prevention-of-aortic-dissection-suggests-a-diameter-shift-to-a-lower-aortic-size-threshold-for-intervention
#1
Ahmed M Mansour, Sven Peterss, Mohammad A Zafar, John A Rizzo, Hai Fang, Paris Charilaou, Bulat A Ziganshin, Umer M Darr, John A Elefteriades
BACKGROUND: Multiple studies have quantified the relationship between aortic size and risk of dissection. However, these studies estimated the risk of dissection without accounting for any increase in aortic size from the dissection process itself. OBJECTIVES: This study aims to compare aortic size before and after dissection and to evaluate the change in size consequent to the dissection itself. METHODS: Fifty-five consecutive patients (29 type A; 26 type B) with aortic dissection and incidental imaging studies prior to dissection were identified and compared to a control group of aneurysm patients (n = 205)...
January 19, 2018: Cardiology
https://www.readbyqxmd.com/read/29344872/a-laser-microdissection-liquid-chromatography-tandem-mass-spectrometry-workflow-for-post-mortem-analysis-of-brain-tissue
#2
David C Hondius, Jeroen J M Hoozemans, Annemieke J M Rozemuller, Ka Wan Li, August B Smit
Improved speed and sensitivity of mass spectrometry allow the simultaneous quantification of high numbers of proteins from increasingly smaller quantities of tissue sample. Quantitative data of the proteome is highly valuable for providing unbiased information on, for example, protein expression changes related to disease or identifying related biomarkers. In brain diseases the affected area can be small and pathogenic events can be related to a specific cell type in an otherwise heterogeneous tissue type. An emerging approach dedicated to analyzing this type of samples is laser micro-dissection (LMD) combined with LC-MS/MS into a single workflow...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29338980/prevalence-of-bovine-aortic-arch-variant-in-patients-with-aortic-dissection-and-its-implications-in-the-outcome-of-patients-with-acute-type-b-aortic-dissection
#3
Spyridon N Mylonas, Arthurs Barkans, Marius Ante, Jens Wippermann, Dietmar Böckler, Jan Sigge Brunkwall
OBJECTIVE/BACKGROUND: To investigate the prevalence of bovine arch (BA) among patients with type A and B aortic dissection, and to provide insight into the implication of this variation on the outcome of patients with acute or subacute type B aortic dissection (a/sTBAD). METHODS: This retrospective cohort analysis includes patients with a/sTBAD admitted between January 2006 and December 2016. Computed tomographic angiograms (CTAs) of patients referred because of type A aortic dissection were also re-evaluated with regard to the presence of BA...
January 12, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29334863/totally-percutaneous-fenestration-via-the-cheese-wire-technique-to-facilitate-endovascular-aneurysm-repair-in-chronic-aortic-dissection
#4
Jordan R Stern, Danielle E Cafasso, Darren B Schneider, Andrew J Meltzer
Here, we describe a totally percutaneous technique for longitudinal fenestration of a chronic dissection flap in the setting of endovascular aneurysm repair (EVAR), where the septum would otherwise preclude proper endograft sealing. This technique is demonstrated in a 65-year-old man with a history of open surgical repair of a Stanford type A aortic dissection, with a type B component that was managed nonoperatively. The patient developed aneurysmal degeneration of the infrarenal aorta during follow-up, and his anatomy was well suited for EVAR with the exception of a chronic dissection flap dividing the proximal seal zone...
January 1, 2018: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29331052/flow-pattern-analysis-in-type-b-aortic-dissection-patients-after-stent-grafting-repair-comparison-between-complete-and-incomplete-false-lumen-thrombosis
#5
Wan Naimah Wan Ab Naim, Poo Balan Ganesan, Zhonghua Sun, Jing Lei, Shirley Jansen, Shahrul Amry Hashim, Teik Kok Ho, Einly Lim
Endovascular stent graft repair has become a common treatment for complicated Stanford Type B aortic dissection in order to restore true lumen flow and induce false lumen thrombosis. Using computational fluid dynamics, this study reports the differences in flow patterns and wall shear stress distribution in complicated Stanford Type B aortic dissection patients after endovascular stent graft repair. Five patients were included in this study: two having more than 80% false lumen thrombosis (Group 1), while three others had less than 80% false lumen thrombosis (Group 2) within one year following endovascular repair...
January 13, 2018: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/29330354/the-res-complex-is-required-for-efficient-transformation-of-the-precatalytic-b-spliceosome-into-an-activated-bact-complex
#6
Penghui Bao, Cindy L Will, Henning Urlaub, Kum-Loong Boon, Reinhard Lührmann
The precise function of the trimeric retention and splicing (RES) complex in pre-mRNA splicing remains unclear. Here we dissected the role of RES during the assembly and activation of yeast spliceosomes. The efficiency of pre-mRNA splicing was significantly lower in the absence of the RES protein Snu17, and the recruitment of its binding partners, Pml1 (pre-mRNA leakage protein 1) and Bud13 (bud site selection protein 13), to the spliceosome was either abolished or substantially reduced. RES was not required for the assembly of spliceosomal B complexes, but its absence hindered efficient Bact complex formation...
January 12, 2018: Genes & Development
https://www.readbyqxmd.com/read/29325358/-correlation-between-of-aortic-dissection-onset-and-climate-change
#7
J T Qiu, L Zhang, X J Luo, J Yang, S Liu, W X Jiang, C T Yu
Objective: To explore the relationship between the incidence of aortic dissection and climate change. Methods: The characteristics of 345 acute aortic dissection patients came from Beijing in Department of Vascular Surgery, Fu Wai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College from January 2005 to December 2015 were analyzed, retrospectively. There were 266 male and 79 female patients with a mean age of (49±12) years. There were 209 cases of Stanford type A aortic dissection, and 136 cases of type B...
January 1, 2018: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/29322965/endovascular-strategies-for-management-of-intradural-vertebral-artery-dissecting-aneurysms
#8
Swati D Chinchure, Vijay Jaykrishnan, B P Krishna Prasad
OBJECTIVE: Endovascular treatment of vertebral intradural dissecting aneurysms is complex and requires different strategies for each case. The current study aims to classify these aneurysms for an easy selection of optimal strategies for endovascular therapy. MATERIALS AND METHODS: This study is a retrospective evaluation of 10 patients harbouring a vertebral intradural dissecting aneurysm (including 6 female and 4 male patients). The clinical, procedural, and angiographic data were evaluated...
January 2018: Neurology India
https://www.readbyqxmd.com/read/29313164/treatment-of-nonocclusive-mesenteric-ischemia-with-type-b-aortic-dissection-using-intra-arterial-catheterization-after-trauma-surgery-case-report
#9
Sho Fujiwara, Yuki Sekine, Ryuichi Nishimura, Kazuya Tadasa, Shukichi Miyazaki
BACKGROUND: Nonocclusive mesenteric ischemia (NOMI) is a mesenteric arterial spasm and intestinal ischemia. This disease is a highly lethal disease because diagnosis and decision of appropriate treatments are often difficult. Operations cannot resolve the spasms and may worsen the situation. However, the safety and effectiveness of catheterization for NOMI with aortic dissection (AD) have not yet been elucidated. Here, we report a successful case of early diagnosis and treatment of NOMI with type B AD involving the superior mesenteric artery (SMA) using the intra-arterial infusion of a vasodilator via the SMA...
January 8, 2018: Surgical Case Reports
https://www.readbyqxmd.com/read/29306626/mid-term-outcomes-of-endovascular-repair-of-ruptured-thoraco-abdominal-aortic-aneurysms-with-off-the-shelf-branched-stent-grafts
#10
Kiattisak Hongku, Björn Sonesson, Katarina Björses, Jan Holst, Timothy Resch, Nuno V Dias
OBJECTIVE: To assess the mid-term outcomes and feasibility of branched endovascular repair (b-EVAR) of ruptured thoracoabdominal aortic aneurysms (rTAAAs). METHODS: All patients undergoing b-EVAR of rTAAAs between 2011 and 2016 were included. Pre-, intra and postoperative imaging was reviewed to assess technical success, outcomes, and feasibility of b-EVAR in the emergent setting. RESULTS: Eleven emergency b-EVAR of rTAAAs (10 aneurysms and 1 chronic dissection) were performed using off-the-shelf (OTS) branched stentgrafts...
January 3, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29303142/type-a-intramural-hematoma-in-a-patient-with-acute-coronary-syndrome-mimicking-acute-type-a-aortic-dissection
#11
Ö Gülmez, B Saritas, I Isiklar
Intramural hematoma (IMH) of ascending aorta is a rare but potentially lethal form of acute aortic syndrome (AAS). It is characterized by a hematoma within the media layer of the aorta secondary to rupture of the vasa vasorum in the absence of an intimal tear. However, the theory of "micro-tear" which cannot be easily detected has been raised. It may stabilize, regress, or progress to rupture or dissection. Similar to Type A aortic dissection (AD), patients with IMH of ascending aorta, as well as patients with persistent pain, are treated urgent surgery...
November 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29300002/design-strategies-for-dynamic-closed-loop-optogenetic-neurocontrol-in-vivo
#12
Michael F Bolus, Adam A Willats, Clarissa J Whitmire, Christopher J Rozell, Garrett B Stanley
Controlling neural activity enables the possibility of manipulating sensory perception, cognitive processes, and body movement, in addition to providing a powerful framework for functionally disentangling the neural circuits that underlie these complex phenomena. Over the last decade, optogenetic stimulation has become an increasingly important and powerful tool for understanding neural circuit function, owing to the ability to target specific cell types and bidirectionally modulate neural activity. To date, most stimulation has been provided in open-loop or in an on/off closed-loop fashion, where previously-determined stimulation is triggered by an event...
January 4, 2018: Journal of Neural Engineering
https://www.readbyqxmd.com/read/29299457/the-impact-of-thoracic-endovascular-aortic-repair-on-long-term-survival-in-type-b-aortic-dissection
#13
EDITORIAL
Christos D Karkos, Ignacio Hernandez-Lahoz, Nikolaos Asaloumidis, Konstantinos O Papazoglou
No abstract text is available yet for this article.
December 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/29296700/il-33-il-25-and-tslp-induce-a-distinct-phenotypic-and-activation-profile-in-human-type-2-innate-lymphoid-cells
#14
Ana Camelo, Guglielmo Rosignoli, Yoichiro Ohne, Ross A Stewart, Catherine Overed-Sayer, Matthew A Sleeman, Richard D May
Innate lymphoid cells (ILCs) represent a distinct branch of the lymphoid lineage composed of 3 major subpopulations: ILC1, ILC2, and ILC3. ILCs are mainly described as tissue-resident cells but can be detected at low levels in human blood. However, unlike mouse ILCs, there is still no consistent methodology to purify and culture these cells that enables in-depth analysis of their intrinsic biology. Here, we describe defined culture conditions for ILC2s, which allowed us to dissect the roles of interleukin 2 (IL-2), IL-25, IL-33, and thymic stromal lymphopoietin (TSLP) individually, or in combination, in modulating ILC2 phenotype and function...
April 11, 2017: Blood Advances
https://www.readbyqxmd.com/read/29290819/identification-of-type-iv-collagen-exposure-as-a-molecular-imaging-target-for-early-detection-of-thoracic-aortic-dissection
#15
Ke Xu, Chen Xu, Yanzhenzi Zhang, Feiran Qi, Bingran Yu, Ping Li, Lixin Jia, Yulin Li, Fu-Jian Xu, Jie Du
Thoracic aortic dissection (TAD) is an aggressive and life-threatening vascular disease and there is no effective means of early diagnosis of dissection. Type IV collagen (Col-IV) is a major component of the sub-endothelial basement membrane, which is initially exposed followed by endothelial injury as early-stage event of TAD. So, we want to build a noninvasive diagnostic method to detect early dissection by identifying the exposed Col-IV via MRI. METHODS: Col-IV-targeted magnetic resonance/ fluorescence dual probe (Col-IV-DOTA-Gd-rhodamine B; CDR) was synthesized by amide reaction and coordination reaction...
2018: Theranostics
https://www.readbyqxmd.com/read/29277670/influence-of-timing-after-thoracic-endovascular-aortic-repair-for-acute-type-b-aortic-dissection
#16
Takeshi Miyairi, Hiroaki Miyata, Kiyoshi Chiba, Hiroshi Nishimaki, Yukihisa Ogawa, Noboru Motomura, Shinichi Takamoto
BACKGROUND: This study aimed to analyze the influence of the timing of intervention from presentation of symptoms to thoracic endovascular aortic repair (TEVAR) and its relation to major complications. Data were collected from the Japan Adult Cardiovascular Surgery Database. METHODS: We retrospectively analyzed the data of 680 patients who underwent TEVAR for acute and subacute type B dissection between January 2008 and January 2013. RESULTS: TEVAR for type B dissection was performed in 680 patients: 295 were performed within 24 hours of presentation of symptoms (hyperacute), 97 between 24 hours and 14 days (acute), and 288 between 14 days and 6 weeks (subacute)...
December 22, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29276106/natural-history-of-the-proximal-aorta-in-patients-with-descending-thoracic-aortic-disease
#17
Paul C Tang, Paul D DiMusto, Nilto C De Oliveira, Brooks L Rademacher, Jennifer L Philip, Shahab A Akhter, Charles W Acher
OBJECTIVE: This study investigated the growth and behavior of the ascending aorta in patients with descending thoracic aortic disease. METHODS: We examined 200 patients with descending thoracic aortic disease including acute type B dissection (n = 95), chronic type B dissection (n = 38), intramural hematoma (n = 23), and thoracoabdominal aortic aneurysms (n = 44). Images from computed tomography and magnetic resonance imaging were evaluated after three-dimensional reconstruction to examine the growth rate in those with >1 year of imaging follow-up (n = 108)...
December 21, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29258498/anatomical-variations-of-the-palmaris-longus-muscle-including-its-relation-to-the-median-nerve-a-proposal-for-a-new-classification
#18
Łukasz Olewnik, Grzegorz Wysiadecki, Michał Polguj, Michał Podgórski, Hubert Jezierski, Mirosław Topol
BACKGROUND: The palmaris longus (PL) muscle is characterised by high morphological diversity, and its tendon crosses the median nerve (MN) at different levels. Due to the fact that the palmaris longus tendon is routinely harvested for reconstruction of other tendons, knowledge of its morphological variations is clinically important. Therefore, the purpose of the study was to suggest a new morphological classification of the PL muscle and characterise the relationship of its tendon to the median nerve...
December 19, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29249788/-usefulness-of-thoracic-endovascular-aortic-repair-for-the-treatment-of-massive-hemoptysis-due-to-bronchiectasis-report-of-two-cases
#19
Akihiko Sasaki, Shuhei Nishijima, Hitoki Hashiguchi
Massive hemoptysis caused by bronchiectasis threatens life, so early bronchial arterial embolization (BAE) is needed. In case 1, a 80-year-old female complained of hemoptysis and back pain caused by bronchiectasis and Stanford type B aortic dissection. In case 2, a 78-year-old male had history of the surgery of descending thoracic aortic aneurysm and bronchiectasis combined with aortopulmonary fistula. Both cases in bronchiectasis with massive hemoptysis were difficult to perform BAE due to complicated with acute aortic dissection and aortopulmonary fistula...
December 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/29247114/protocol-for-the-robust-registry-of-type-b-aortic-dissection-with-the-utility-of-stent-graft-study-an-ambispective-multicentre-open-cohort-study
#20
Dan Rong, Yangyang Ge, Yan Xue, Feng Liu, Kai Lu, Peng Liu, Lei Zhang, Xiaohu Ge, Jianhang Miu, Linkun Zhong, Weidong Fan, Hongpeng Zhang, Xin Jia, Xiaohui Ma, Jiang Xiong, Xiaoping Liu, Wei Guo
INTRODUCTION: Thoracic endovascular aortic repair (TEVAR) is widely used for type B aortic dissection, although with satisfactory outcome in a limited proportion of patients. To better inform patient prognostication, the Registry Of type B aortic dissection with the Utility of STent graft (ROBUST) study aims to identify imaging-based predictors of post-TEVAR adverse outcomes up to 10-year follow-up. METHODS AND ANALYSIS: ROBUST is designed as an ambispective, multicentre, open cohort study...
December 14, 2017: BMJ Open
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