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https://www.readbyqxmd.com/read/29352722/daily-intake-of-mucuna-pruriens-in-advanced-parkinson-s-disease-a-16-week-noninferiority-randomized-crossover-pilot-study
#1
Roberto Cilia, Janeth Laguna, Erica Cassani, Emanuele Cereda, Benedetta Raspini, Michela Barichella, Gianni Pezzoli
BACKGROUND: Thousands of individuals with Parkinson's disease (PD) in low-income countries have limited access to marketed levodopa preparations. Mucuna pruriens (MP), a levodopa-containing leguminous plant growing in tropical areas, may be a sustainable alternative therapy for indigent patients. Single-dose intake of MP proved noninferior to marketed levodopa preparations. METHODS: Fourteen PD patients with motor fluctuations and dyskinesias received MP powder (obtained from roasted seeds) and marketed levodopa/carbidopa (LD/CD) in a randomized order and crossover design over a 16-week period...
January 11, 2018: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29345745/comparison-of-flow-cytometric-methods-for-the-enumeration-of-residual-leucocytes-in-leucoreduced-blood-products-a-multicenter-study
#2
Yang Zeng, Michelle Dabay, Virginia George, Shalini Seetharaman, Monika de Arruda Indig, Sharon Graminske, Nicole Kimpel, Anna Schmidt, Amanda Boerner, Sarai Paradiso, Tatyana Delman, Yunyao Li, Viktoriya Litvak, Farzad Oreizy, Angela Chen, Maryam Saleminik, Fred Mosqueda, Anna Lin, Kevin Judge
The BD FACSVia™ System features novel designs in hardware, software, and instrument QC. We compared the performance of the BD FACSVia System using the BD Leucocount™ kit with the BD FACSCalibur™ flow cytometer. Leucoreduced platelet (PLT, n = 252) and red blood cell (RBC, n = 278) specimens were enrolled at four sites. Each specimen was stained in four tubes using the BD Leucocount kit reagents and acquired on the two systems. BD Leucocount Control cells (high and low) were used to evaluate the inter-site reproducibility on the BD FACSVia System at three sites over 20 days...
January 18, 2018: Cytometry. Part A: the Journal of the International Society for Analytical Cytology
https://www.readbyqxmd.com/read/29310690/street-level-workers-inadequate-knowledge-and-application-of-exemption-policies-in-burkina-faso-jeopardize-the-achievement-of-universal-health-coverage-evidence-from-a-cross-sectional-survey
#3
Valéry Ridde, Gerald Leppert, Hervé Hien, Paul Jacob Robyn, Manuela De Allegri
BACKGROUND: Street-level workers play a key role in public health policies in Africa, as they are often the ones to ensure their implementation. In Burkina Faso, the State formulated two different user-fee exemption policies for indigents, one for deliveries (2007), and one for primary healthcare (2009). The objective of this study was to measure and understand the determinants of street-level workers' knowledge and application of these exemption measures. METHODS: We used cross-sectional data collected between October 2013 and March 2014...
January 8, 2018: International Journal for Equity in Health
https://www.readbyqxmd.com/read/29297402/bridging-access-gaps-experienced-by-the-underserved-the-need-for-healthcare-providers-to-look-within-for-answers
#4
James K Elrod, John L Fortenberry
BACKGROUND: Health and medical providers dedicated to serving the poor face daunting challenges, with the most obvious one pertaining to the provision of services with little or no expectation of remuneration. This hardship often is overlooked by broad society as many view the delivery of healthcare services to indigent populations to be covered fully by government health insurance programs or other forms of public assistance. This, however, is only partially true and, even when reimbursements or similar payments are provided, they often fall short of covering the actual costs associated with rendering services...
December 13, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29297342/advancing-indigent-healthcare-services-through-adaptive-reuse-repurposing-abandoned-buildings-as-medical-clinics-for-disadvantaged-populations
#5
James K Elrod, John L Fortenberry
BACKGROUND: Challenges abound for healthcare providers engaged in initiatives directed toward disadvantaged populations, with financial constraints representing one of the most prominent hardships. Society's less fortunate typically lack the means to pay for healthcare services and even when they are covered by government health insurance programs, reimbursement shortcomings often occur, placing funding burdens on the shoulders of establishments dedicated to serving those of limited means...
December 13, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29288470/assessing-racial-disparities-in-hcv-infection-and-care-outcomes-in-a-southern-urban-population
#6
Keanan McGonigle, Tess Carley, Clarissa Hoff
OBJECTIVES: This study assessed racial disparities in access to healthcare services, hepatitis C virus (HCV) exposure, and retention in a treatment cascade in two indigent populations in an urban center in the Southern US. PARTICIPANTS/METHODS: Opt-in HCV antibody screening was offered at two large homeless centers and three residential substance abuse treatment centers (SATCs) in New Orleans, LA. Five hundred ninety-four participants experiencing homelessness and 342 residents of SATCs were assessed for previous access/perceived barriers to healthcare services and high-risk behaviors associated with HCV exposure...
December 29, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/29191142/forensic-experts-indigent-defendants-and-the-constitution
#7
Paul S Appelbaum
Over 30 years ago, the U.S. Supreme Court held that indigent defendants raising psychiatric issues are entitled to the assistance of a mental health expert. However, the exact dimensions of that assistance, and whether the expert must be assigned exclusively to assist the defense, have been in contention ever since. In its recent decision in McWilliams v. Dunn, the Court underscored that the state-funded expert must be available to consult with the defense, not merely to evaluate the defendant, but declined to opine on whether the defense is entitled to its own expert for the purpose...
December 1, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/29176100/utilization-and-cost-analysis-of-a-chronically-ill-newly-insured-indigent-population
#8
Jong-Deuk Baek, Robert L Seidman, Tracy L Finlayson
The Affordable Care Act expanded health insurance for low-income, uninsured individuals. Few longitudinal analyses have investigated how insurance expansion influences cost and utilization among adults with chronic conditions. This study conducted longitudinal analysis investigating time trends in utilization and cost among newly insured, chronically ill, low-income individuals using Generalized Estimating Equations models. For hospitalization, hospital outpatient services, emergency department (ED) visits, and primary care visits, two indicators were measured: the proportion of enrollees with services and the average number of visits among users...
2017: Journal of Health Care for the Poor and Underserved
https://www.readbyqxmd.com/read/29157568/providing-primary-care-using-an-interprofessional-collaborative-practice-model-what-clinicians-have-learned
#9
Cynthia S Selleck, Matthew Fifolt, Heidi Burkart, Jennifer Sandson Frank, William A Curry, Lisle S Hites
This article details a nurse-led, interprofessional collaborative practice (IPCP) model that was developed to provide primary care to a medically indigent population in Birmingham, Alabama. Funding to develop and implement this project came from a federal Nurse Education, Practice, Quality and Retention award to the University of Alabama at Birmingham (UAB) School of Nursing, with additional support coming from the UAB Hospital and Health System. The clinic is housed within a local community-based, non-profit organization and all services, including supplies and pharmaceuticals, are provided free of charge to this vulnerable population...
November 2017: Journal of Professional Nursing: Official Journal of the American Association of Colleges of Nursing
https://www.readbyqxmd.com/read/29143090/pattern-of-lower-intestinal-ostomies-in-a-low-income-country-case-of-southeast-of-niger-republic
#10
Harissou Adamou, Oumarou Habou, Ibrahim Amadou Magagi, Ousseini Adakal, Amadou Magagi, Maazou Halidou, Rachid Sani
BACKGROUND: Intestinal ostomies are common surgical procedures performed in visceral surgery as part of management for several gastrointestinal diseases. This study aims to report the socio-demographic characteristics, indications and prognosis of intestinal ostomies in low-income country. METHODS: This was a 4-year retrospective study (January 2013 to December 2016) at Zinder National Hospital (Niger). All patients with a digestive ostomy on an ileum or colic segment were included in the study...
November 15, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29131469/do-programs-for-aboriginal-and-torres-strait-islander-people-leaving-prison-meet-their-health-and-social-support-needs
#11
REVIEW
Penelope Abbott, Jane E Lloyd, Chandni Joshi, Kathy Malera-Bandjalan, Eileen Baldry, Elizabeth McEntyre, Juanita Sherwood, Jennifer Reath, Devon Indig, Mark F Harris
The objective of this review was to synthesise evidence on the health and social support needs of Aboriginal and Torres Strait Islander people leaving prison and on programs which aid successful community re-entry. A systematic literature review was undertaken of peer-reviewed and grey literature published between 2001 and 2013, focusing on the post-release needs of Aboriginal and Torres Strait Islander adults and pre- and post-release programs. Aboriginal and Torres Strait Islander people have high health and social support needs on leaving prison...
November 13, 2017: Australian Journal of Rural Health
https://www.readbyqxmd.com/read/29129738/timing-of-referral-and-characteristics-of-uninsured-medicaid-and-insured-patients-referred-to-the-outpatient-supportive-care-center-at-a-comprehensive-cancer-center
#12
Ahsan Azhar, Sriram Yennurajalingam, Aashraya Ramu, Haibo Zhang, Ali Haider, Janet L Williams, Seyedeh S Dibaj, Diane D Liu, Eduardo Bruera
CONTEXT: Low-income patients face barriers to palliative care access, which might negatively influence symptom management and advanced care planning. OBJECTIVE: Our aim was to compare time of referral and characteristics (level of symptom distress) among uninsured (indigent), low-insured (Medicaid), and insured patients presenting to our Supportive Care Center (SCC). METHODS: We conducted a retrospective review of randomly selected 100 indigent, 100 Medicaid and 300 insured outpatients referred during the same 5-year period...
November 9, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29051984/harnessing-advances-in-computer-simulation-to-inform-policy-and-planning-to-reduce-alcohol-related-harms
#13
Jo-An Atkinson, Dylan Knowles, John Wiggers, Michael Livingston, Robin Room, Ante Prodan, Geoff McDonnell, Eloise O'Donnell, Sandra Jones, Paul S Haber, David Muscatello, Nadine Ezard, Nghi Phung, Louise Freebairn, Devon Indig, Lucie Rychetnik, Jaithri Ananthapavan, Sonia Wutzke
OBJECTIVES: Alcohol misuse is a complex systemic problem. The aim of this study was to explore the feasibility of using a transparent and participatory agent-based modelling approach to develop a robust decision support tool to test alcohol policy scenarios before they are implemented in the real world. METHODS: A consortium of Australia's leading alcohol experts was engaged to collaboratively develop an agent-based model of alcohol consumption behaviour and related harms...
October 19, 2017: International Journal of Public Health
https://www.readbyqxmd.com/read/28993378/characterisation-of-the-rural-indigent-population-in-burkina-faso-a-screening-tool-for-setting-priority-healthcare-services-in-sub-saharan-africa
#14
Samiratou Ouédraogo, Valéry Ridde, Nicole Atchessi, Aurélia Souares, Jean-Louis Koulidiati, Quentin Stoeffler, Maria-Victoria Zunzunegui
BACKGROUND: In Africa, health research on indigent people has focused on how to target them for services, but little research has been conducted to identify the social groups that compose indigence. Our aim was to identify what makes someone indigent beyond being recognised by the community as needing a card for free healthcare. METHODS: We used data from a survey conducted to evaluate a state-led intervention for performance-based financing of health services in two districts of Burkina Faso...
October 8, 2017: BMJ Open
https://www.readbyqxmd.com/read/28970406/serving-with-pharmacy-students-reflections-from-a-medical-mission-team-leader-and-preceptor
#15
Dana A Brown
The medical mission field is an innovative setting for training and evaluating health care professional students. The motivating factor of serving indigent populations as a means of a humanitarian, or oftentimes a spiritual act, makes medical missions an attractive option for student participation. At the Gregory School of Pharmacy, medical mission teams are an integral part of the pharmacy program, including the opportunity for students to earn elective credit during their fourth year. This commentary provides five key elements to consider when serving with, training and evaluating pharmacy students from the perspective of a team leader and preceptor...
October 24, 2016: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/28957575/defining-social-work-within-holistic-public-defense-challenges-and-implications-for-practice
#16
Sarah Buchanan, Roger M Nooe
Social work has a history of forensic practice, but social work as an integral component of the holistic model of public defense is new and is creating a demand for better definition of roles and services. The intent of this article is to contribute to and encourage dialogue surrounding social work practice within the holistic public defense model. A brief overview of the indigent criminal defense system and its emerging models of defense practice is provided. Models of practice established by the Knox County Public Defender's Community Law Office are offered...
October 1, 2017: Social Work
https://www.readbyqxmd.com/read/28877934/identification-of-senescent-cell-surface-targetable-protein-dpp4
#17
Kyoung Mi Kim, Ji Heon Noh, Monica Bodogai, Jennifer L Martindale, Xiaoling Yang, Fred E Indig, Sandip K Basu, Kei Ohnuma, Chikao Morimoto, Peter F Johnson, Arya Biragyn, Kotb Abdelmohsen, Myriam Gorospe
Senescent cell accumulation in aging tissues is linked to age-associated diseases and declining function, prompting efforts to eliminate them. Mass spectrometry analysis revealed that DPP4 (dipeptidyl peptidase 4) was selectively expressed on the surface of senescent, but not proliferating, human diploid fibroblasts. Importantly, the differential presence of DPP4 allowed flow cytometry-mediated isolation of senescent cells using anti-DPP4 antibodies. Moreover, antibody-dependent cell-mediated cytotoxicity (ADCC) assays revealed that the cell surface DPP4 preferentially sensitized senescent, but not dividing, fibroblasts to cytotoxicity by natural killer cells...
August 1, 2017: Genes & Development
https://www.readbyqxmd.com/read/28831355/elizabeth-croll-asps-patient-of-courage-2016
#18
Arun K Gosain
Mrs. Elizabeth Croll was selected as an American Society of Plastic Surgeons (ASPS) Patient of Courage in 2016. During a boating accident that occurred within 1 month after graduating from Harvard Business School, she was struck by an oncoming boat and suffered severe facial trauma, resulting in an open skull injury with loss of her right eye. She has since undergone multiple reconstructive surgical procedures beginning in 1997 and continuing up to the month before she was awarded the ASPS Patient of Courage...
July 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28814837/simulating-clinical-trial-visits-yields-patient-insights-into-study-design-and-recruitment
#19
S Sam Lim, Alan J Kivitz, Doug McKinnell, M Edward Pierson, Faye S O'Brien
PURPOSE: We elicited patient experiences from clinical trial simulations to aid in future trial development and to improve patient recruitment and retention. PATIENTS AND METHODS: Two simulations of draft Phase II and Phase III anifrolumab studies for systemic lupus erythematosus (SLE)/lupus nephritis (LN) were performed involving African-American patients from Grady Hospital, an indigent care hospital in Atlanta, GA, USA, and white patients from Altoona Arthritis and Osteoporosis Center in Altoona, PA, USA...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/28811088/primary-prevention-aspirin-use-in-high-risk-patients-a-pharmacist-intervention-and-comparison-of-risk-stratification-tools
#20
Scott A Coon, Amie D Brooks, Stephen E Wolff
OBJECTIVES: The objectives of this project are 1) to describe aspirin use for primary prevention in an underserved, minority population; 2) to determine the impact of a pharmacist-led intervention on the prevalence of aspirin use for primary prevention; and 3) to compare aspirin indications based on Framingham Risk Score (FRS) and atherosclerotic cardiovascular disease (ASCVD) risk score. METHODS: Men and women age 45-79 and 55-79 years, respectively, without ASCVD were screened for aspirin use...
August 12, 2017: Journal of the American Pharmacists Association: JAPhA
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