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https://www.readbyqxmd.com/read/28282245/live-with-the-disease-like-you-used-to-before-you-knew-you-were-infected-a-qualitative-study-among-10-year-survivors-living-with-hiv-in-haiti
#1
Samuel Pierre, Vanessa Riviera, Circee Phara Jean, Marie Jude Jean Louis, Lindsey K Reif, Patrice Severe, Vanessa Rouzier, Warren D Johnson, Jean W Pape, Daniel W Fitzgerald, Margaret L McNairy, Carla Boutin-Foster
In 2003, the Haitian Study Group on Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), a nonprofit organization, began administering antiretroviral therapy (ART) to its patients. This practice transformed HIV from a fatal disease to a more manageable chronic condition. However, relatively few studies focus on the experiences of survivors. This study provided a unique opportunity to interview patients who survived at least 10 years after being treated with ART at GHESKIO. The goal of the study was to elicit from patients their perspectives on what enabled them to survive with AIDS...
March 2017: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/28254516/relationship-between-teach-back-and-patient-centered-communication-in-primary-care-pediatric-encounters
#2
Adam Badaczewski, Laurie J Bauman, Arthur E Blank, Benard Dreyer, Mary Ann Abrams, Ruth E K Stein, Debra L Roter, Jobayer Hossain, Hal Byck, Iman Sharif
OBJECTIVE: We proposed and tested a theoretical framework for how use of Teach-back could influence communication during the pediatric clinical encounter. METHODS: Audio-taped pediatric primary care encounters with 44 children with asthma were coded using the Roter Interaction Analysis System to measure patient-centered communication and affective engagement of the parent. A newly created Teach-back Loop Score measured the extent to which Teach-back occurred during the clinical encounter; parental health literacy was measured by Newest Vital Sign...
February 24, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28230906/evaluation-of-skin-surface-as-an-alternative-source-of-reference-dna-samples-a-pilot-study
#3
Mohammed H Albujja, Abdul Aziz Bin Dukhyil, Abdul Rauf Chaudhary, Ahmed Ch Kassab, Ahmed M Refaat, Saranya Ramesh Babu, Mohammad K Okla, Sachil Kumar
An acceptable area for collecting DNA reference sample is a part of the forensic DNA analysis development. The aim of this study was to evaluate skin surface cells (SSC) as an alternate source of reference DNA sample. From each volunteer (n = 10), six samples from skin surface areas (forearm and fingertips) and two traditional samples (blood and buccal cells) were collected. Genomic DNA was extracted and quantified then genotyped using standard techniques. The highest DNA concentration of SSC samples was collected using the tape/forearm method of collection (2...
February 23, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28220852/transfer-of-monolayer-tmd-ws2-and-raman-study-of-substrate-effects
#4
Jerome T Mlack, Paul Masih Das, Gopinath Danda, Yung-Chien Chou, Carl H Naylor, Zhong Lin, Néstor Perea López, Tianyi Zhang, Mauricio Terrones, A T Charlie Johnson, Marija Drndić
A facile transfer process for transition metal dichalcogenide WS2 flakes is reported and the effect of the underlying substrate on the flake properties is investigated using Raman spectroscopy. The flakes are transferred from their growth substrate using polymethyl methacrylate (PMMA) and a wet etch to allow the user to transfer the flakes to a final substrate using a microscope and micromanipulator combined with semi-transparent Kapton tape. The substrates used range from insulators such as industry standard high-k dielectric HfO2 and "green polymer" parylene-C, to conducting chemical vapor deposition (CVD) grown graphene...
February 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28139863/role-of-intrinsic-sphincter-deficiency-with-and-without-urethral-hypomobility-on-the-outcome-of-tape-insertion
#5
Edyta Wlaźlak, Volker Viereck, Jacek Kociszewski, Andrzej Kuszka, Oliver Rautenberg, Claudia Walser, Grzegorz Surkont, Marianne Gamper, Mathias K Fehr
AIMS: Intrinsic sphincter deficiency (ISD) is a known risk factor for therapy failure after tension-free vaginal tape (TVT) insertion. The purpose of this study was to investigate if the severity of ISD alone or other factors such as urethral mobility and tape localization influence outcomes. METHODS: One hundred and nine women with urodynamically determined ISD, a TVT insertion, and a 6-month follow-up visit were included. Urethral length, mobility, and tape localization were evaluated by pelvic floor sonography...
January 31, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28139006/comparison-of-protocols-measuring-diffusion-and-partition-coefficients-in-the-stratum-corneum
#6
H Rothe, C Obringer, J Manwaring, C Avci, W Wargniez, J Eilstein, N Hewitt, R Cubberley, H Duplan, D Lange, C Jacques-Jamin, M Klaric, A Schepky, S Grégoire
Partition (K) and diffusion (D) coefficients are important to measure for the modelling of skin penetration of chemicals through the stratum corneum (SC). We compared the feasibility of three protocols for the testing of 50 chemicals in our main studies, using three cosmetics-relevant model chemicals with a wide range of logP values. Protocol 1: SC concentration-depth profile using tape-stripping (measures KSC/v and DSC /HSC(2) , where HSC is the SC thickness); Protocol 2A: incubation of isolated SC with chemical (direct measurement of KSC/v only) and Protocol 2B: diffusion through isolated SC mounted on a Franz cell (measures KSC/v and DSC /HSC(2) , and is based on Fick's laws)...
January 31, 2017: Journal of Applied Toxicology: JAT
https://www.readbyqxmd.com/read/28126662/on-chip-electrochemical-immunoassay-platform-for-specific-protein-biomarker-estimation-in-undiluted-serum-using-off-surface-membrane-matrix
#7
Sunil K Arya, Patthara Kongsuphol, Mi Kyoung Park
The manuscript presents a new biosensor platform using bioreceptors modified porous 2-dimensional (2D) membrane based off-surface matrix for on-chip electrochemical immunoassay. Antibody based bioreceptors modified 2D matrix of porous polycarbonate (PC) membrane with densely packed 20µm holes as off-surface matrix was incorporated in very close proximity of the sensor surface and integrated with fluidic system for reagent flow and incubation chamber. Covalent attachment of antibodies on 2D PC membrane based off-matrix was achieved using 4-fluoro-3-nitro-azidobenzene (FNAB) cross-linker...
May 15, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28105396/a-solution-doped-polymer-semiconductor-insulator-blend-for-thermoelectrics
#8
David Kiefer, Liyang Yu, Erik Fransson, Andrés Gómez, Daniel Primetzhofer, Aram Amassian, Mariano Campoy-Quiles, Christian Müller
Poly(ethylene oxide) is demonstrated to be a suitable matrix polymer for the solution-doped conjugated polymer poly(3-hexylthiophene). The polarity of the insulator combined with carefully chosen processing conditions permits the fabrication of tens of micrometer-thick films that feature a fine distribution of the F4TCNQ dopant:semiconductor complex. Changes in electrical conductivity from 0.1 to 0.3 S cm(-1) and Seebeck coefficient from 100 to 60 μV K(-1) upon addition of the insulator correlate with an increase in doping efficiency from 20% to 40% for heavily doped ternary blends...
January 2017: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://www.readbyqxmd.com/read/28074570/development-of-the-sbirt-checklist-for-observation-in-real-time-score
#9
Janice A Vendetti, Bonnie G McRee, Frances K Del Boca
BACKGROUND AND AIMS: Screening, Brief Intervention and Referral to Treatment (SBIRT) programs have been implemented widely in medical settings, with little attention focused on how well providers adhere to evidence-based service delivery in everyday practice. The purposes of this paper were to: (1) introduce a flexible, relatively simple methodology, the SBIRT Checklist for Observation in Real-time (SCORe), to assess adherence to evidence-based practice and provide preliminary evidence supporting its criterion validity; and (2) illustrate the feasibility and potential utility of the SCORe by analyzing observations of providers within four large-scale SBIRT programs in the United States...
February 2017: Addiction
https://www.readbyqxmd.com/read/28069155/communicating-with-patients-from-minority-backgrounds-individual-challenges-experienced-by-oncology-health-professionals
#10
Kaaren J Watts, Bettina Meiser, Elvira Zilliacus, Rajneesh Kaur, Mona Taouk, Afaf Girgis, Phyllis Butow, David Goldstein, Sandra Hale, Astrid Perry, Sanchia K Aranda, David W Kissane
PURPOSE: Oncology health professionals (HPs) are increasingly required to care for patients from minority backgrounds. Yet many HPs have not had formal training in how to communicate effectively in culturally diverse settings. More information is needed about the challenges that oncology HPs face in communicating with minority patients to inform the content of formal training programs. This qualitative study aimed to identify oncology nurses' and oncologists' individual experiences and challenges in communicating with patients from minority backgrounds...
February 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/28008987/a-bio-enabled-maximally-mild-layer-by-layer-kapton-surface-modification-approach-for-the-fabrication-of-all-inkjet-printed-flexible-electronic-devices
#11
Yunnan Fang, Jimmy G D Hester, Wenjing Su, Justin H Chow, Suresh K Sitaraman, Manos M Tentzeris
A bio-enabled, environmentally-friendly, and maximally mild layer-by-layer approach has been developed to surface modify inherently hydrophobic Kapton HN substrates to allow for great printability of both water- and organic solvent-based inks thus facilitating the full-inkjet-printing of flexible electronic devices. Different from the traditional Kapton surface modification approaches which are structure-compromising and use harsh conditions to target, and oxidize and/or remove part of, the surface polyimide of Kapton, the present Kapton surface modification approach targeted the surface electric charges borne by its additive particles, and was not only the first to utilize environmentally-friendly clinical biomolecules to build up a thin film of protamine-heparin complex on Kapton, but also the first to be conducted under minimally destructive and maximally mild conditions...
December 23, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27998691/influence-of-the-skin-barrier-on-the-penetration-of-topically-applied-dexamethasone-probed-by-soft-x-ray-spectromicroscopy
#12
K Yamamoto, A Klossek, R Flesch, F Rancan, M Weigand, I Bykova, M Bechtel, S Ahlberg, A Vogt, U Blume-Peytavi, P Schrade, S Bachmann, S Hedtrich, M Schäfer-Korting, E Rühl
The penetration of dexamethasone into human skin ex vivo is reported. X-ray microscopy is used for label-free probing of the drug and quantification of the local drug concentration with a spatial resolution reaching 70±5 nm. This is accomplished by selective probing the dexamethasone by X-ray absorption. Varying the penetration time between 10 min and 1000 min provides detailed information on the penetration process. In addition, the stratum corneum has been damaged by tape-stripping in order to determine the importance of this barrier regarding temporally resolved drug penetration profiles...
December 17, 2016: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/27956654/adapting-and-evaluating-a-rapid-low-cost-method-to-enumerate-flies-in-the-household-setting
#13
Marlene K Wolfe, Holly N Dentz, Beryl Achando, MaryAnne Mureithi, Tim Wolfe, Clair Null, Amy J Pickering
Diarrhea is a leading cause of death among children under 5 years of age worldwide. Flies are important vectors of diarrheal pathogens in settings lacking networked sanitation services. There is no standardized method for measuring fly density in households; many methods are cumbersome and unvalidated. We adapted a rapid, low-cost fly enumeration technique previously developed for industrial settings, the Scudder fly grill, for field use in household settings. We evaluated its performance in comparison to a sticky tape fly trapping method at latrine and food preparation areas among households in rural Kenya...
February 8, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27924913/thermal-alternating-polymer-nanocomposite-tapnc-coating-designed-to-prevent-aerodynamic-insect-fouling
#14
Ilker S Bayer, K Ghokulla Krishnan, Robert Robison, Eric Loth, Douglas H Berry, Thomas E Farrell, Jeffrey D Crouch
Insect residue adhesion to moving surfaces such as turbine blades and aircraft not only causes surface contamination problems but also increases drag on these surfaces. Insect fouling during takeoff, climb and landing can result in increased drag and fuel consumption for aircraft with laminar-flow surfaces. Hence, certain topographical and chemical features of non-wettable surfaces need to be designed properly for preventing insect residue accumulation on surfaces. In this work, we developed a superhydrophobic coating that is able to maintain negligible levels of insect residue after 100 high speed (50 m/s) insect impact events produced in a wind tunnel...
December 7, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27915190/gunshot-residue-and-brakepads-compositional-and-morphological-considerations-for-forensic-casework
#15
William Tucker, Nick Lucas, Kelsey E Seyfang, K Paul Kirkbride, Rachel S Popelka-Filcoff
Previous research has raised the possibility that automotive brake pads can produce particles that are both compositionally and morphologically similar to gunshot residue (GSR). These studies, published in the early 2000s, coincided with the reduction or removal of unnecessary sources of lead from the automotive industry. The question therefore arises whether modern brake pads might still be a relevant source of 'GSR-like' particles. In the present study, a total of 75 brake pads taken from a range of cars currently on the road in Adelaide, South Australia, were collected from service centres...
November 23, 2016: Forensic Science International
https://www.readbyqxmd.com/read/27897018/-ultrasound-comparison-of-adjustable-single-incision-ajust-and-transobturator-tapes-to-assess-post-operative-fixation-and-function-and-clinical-efficacy
#16
F Farhat, K Švabík, P Hubka, A Martan, J Mašata
OBJECTIVE: The aim of this study was to compare fixation and mobility of adjustable single-incision (Ajust) and standard transobturator midurethral sling (TVT-O) tapes based on postoperative ultrasound monitoring of the position of the tape at rest and at maximal Valsava (tape descent). The hypothesis was that fixation of SIMS Ajust is comparable to that achieved by the standard transobturator midurethral sling. SETTING: Gynecology and Obstetrics Department, GUH and 1st Charles University Prague; Gynecology and Obstetrics Department Masarykova nemocnice Ústí nad Labem...
2016: Ceská Gynekologie
https://www.readbyqxmd.com/read/27894032/clinical-outcomes-in-women-undergoing-laparoscopic-hysteropexy-a-systematic-review
#17
REVIEW
R Nair, K I Nikolopoulos, L S Claydon
OBJECTIVES: To systematically review the current evidence on the anatomic and functional outcomes in women undergoing laparoscopic hysteropexy. STUDY DESIGN: An electronic database search was undertaken (2000-2016). Keywords were: "laparoscopy", "hysteropexy", "cervicopexy", "uterine suspension", "uterosacral plication". References of identified studies as well as abstracts from conferences were considered. We restricted the search to humans, female patients and currently used surgical procedures...
January 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27864988/time-to-question-diabetes-self-management-support-for-arabic-speaking-migrants-exploring-a-new-model-of-care
#18
H Alzubaidi, K Mc Namara, C Browning
AIM: The objective of this study was to explore a new model for diabetes self-management support in Arabic-speaking migrants. METHODS: Two qualitative methods were used: face-to-face semi-structured individual interviews and focus groups. Interviews were audio-taped, transcribed verbatim and coded thematically. Arabic-speaking migrants with Type 2 diabetes were recruited from several primary, secondary and tertiary healthcare settings in metropolitan Melbourne, Australia...
November 16, 2016: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/27833118/enhanced-critical-current-in-p-doped-bafe2as2-thin-films-on-metal-substrates-arising-from-poorly-aligned-grain-boundaries
#19
Hikaru Sato, Hidenori Hiramatsu, Toshio Kamiya, Hideo Hosono
Thin films of the iron-based superconductor BaFe2(As1-xPx)2 (Ba122:P) were fabricated on polycrystalline metal-tape substrates with two kinds of in-plane grain boundary alignments (well aligned (4°) and poorly aligned (8°)) by pulsed laser deposition. The poorly aligned substrate is not applicable to cuprate-coated conductors because the in-plane alignment >4° results in exponential decay of the critical current density (Jc). The Ba122:P film exhibited higher Jc at 4 K when grown on the poorly aligned substrate than on the well-aligned substrate even though the crystallinity was poorer...
November 11, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27824369/proteomics-profiling-of-interactome-dynamics-by-colocalisation-analysis-cola
#20
Faraz K Mardakheh, Heba Z Sailem, Sandra Kümper, Christopher J Tape, Ryan R McCully, Angela Paul, Sara Anjomani-Virmouni, Claus Jørgensen, George Poulogiannis, Christopher J Marshall, Chris Bakal
Localisation and protein function are intimately linked in eukaryotes, as proteins are localised to specific compartments where they come into proximity of other functionally relevant proteins. Significant co-localisation of two proteins can therefore be indicative of their functional association. We here present COLA, a proteomics based strategy coupled with a bioinformatics framework to detect protein-protein co-localisations on a global scale. COLA reveals functional interactions by matching proteins with significant similarity in their subcellular localisation signatures...
December 20, 2016: Molecular BioSystems
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