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https://www.readbyqxmd.com/read/28328925/a-source-controlled-data-center-network-model
#1
Yang Yu, Mangui Liang, Zhe Wang
The construction of data center network by applying SDN technology has become a hot research topic. The SDN architecture has innovatively separated the control plane from the data plane which makes the network more software-oriented and agile. Moreover, it provides virtual multi-tenancy, effective scheduling resources and centralized control strategies to meet the demand for cloud computing data center. However, the explosion of network information is facing severe challenges for SDN controller. The flow storage and lookup mechanisms based on TCAM device have led to the restriction of scalability, high cost and energy consumption...
2017: PloS One
https://www.readbyqxmd.com/read/28328490/the-coming-gray-tide-wanted-health-innovations-for-an-increasingly-older-population
#2
Leslie Mertz
The human population is getting older, and technology will play a key role in addressing the pressures this aging will place on healthcare systems. According to the 2015 United Nations' World Population Ageing report [1], the number of people worldwide 60 and older will increase from one in eight in 2015 to one in six by 2030 and to one in five by 2050; in Europe and "Northern America" (mainly the United States and Canada), those 60 and older will make up 25% of the population by 2030, and in Asia and Latin America, the number is predicted to be 17%...
March 2017: IEEE Pulse
https://www.readbyqxmd.com/read/28327993/stepwise-distributed-open-innovation-contests-for-software-development-acceleration-of-genome-wide-association-analysis
#3
Andrew Hill, Po-Ru Loh, Ragu B Bharadwaj, Pascal Pons, Jingbo Shang, Eva Guinan, Karim Lakhani, Iain Kilty, Scott A Jelinsky
BACKGROUND: The association of differing genotypes with disease related phenotypic traits offers great potential to both help identify new therapeutic targets and support stratification of patients who would gain the greatest benefit from specific drug classes. Development of low cost genotyping and sequencing has made collecting large scale genotyping data routine in population and therapeutic intervention studies. In addition, a range of new technologies are being used to capture numerous new and complex phenotypic descriptors...
February 28, 2017: GigaScience
https://www.readbyqxmd.com/read/28326723/-current-dental-implant-design-and-its-clinical-importance
#4
Lin Ye
The development of clinical implant dentistry was intensively affected by dental implant design improvement and innovation, which brought about new concept, even milestone-like changes of clinical protocol. The current improvements of dental implant design and their clinical importance could be highlighted as followings: 1) The implant apical design influences the implant preliminary stability in immediate implant. The apical 3-5 mm design of implant makes implant stable in immediate implant, because this part would be screwed into alveolar bone through fresh socket, the other part of implant could not be tightly screwed in the socket because of smaller implant diameter...
February 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28326490/virtual-reality-educational-tool-for-human-anatomy
#5
Santiago González Izard, Juan A Juanes Méndez, Pablo Ruisoto Palomera
Virtual Reality is becoming widespread in our society within very different areas, from industry to entertainment. It has many advantages in education as well, since it allows visualizing almost any object or going anywhere in a unique way. We will be focusing on medical education, and more specifically anatomy, where its use is especially interesting because it allows studying any structure of the human body by placing the user inside each one. By allowing virtual immersion in a body structure such as the interior of the cranium, stereoscopic vision goggles make these innovative teaching technologies a powerful tool for training in all areas of health sciences...
May 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28325248/bridging-innovation-and-outreach-to-overcome-global-gaps-in-radiation-oncology-through-information-and-communication-tools-trainee-advancement-engaging-industry-attention-to-ethical-challenges-and-political-advocacy
#6
REVIEW
Luqman Dad, Trevor J Royce, Zachary Morris, Meena Moran, Todd Pawlicki, Deepak Khuntia, Patricia Hardenbergh, Bernard Cummings, Nina Mayr, Kenneth Hu
An evolving paradigm in global outreach in radiation oncology has been the implementation of a more region-specific, needs-based approach to help close the gap in radiation services to low- and middle-income countries through the use of innovative tools in information and communication technology. This report highlights 4 information and communication technology tools in action today: (1) the NCCN Framework for Resource Stratification of NCCN guidelines, (2) ASTRO e-Contouring, (3) i.treatsafely.org, and (4) ChartRounds...
April 2017: Seminars in Radiation Oncology
https://www.readbyqxmd.com/read/28325246/challenges-and-prospects-for-providing-radiation-oncology-services-in-africa
#7
REVIEW
Onyinye Balogun, Danielle Rodin, Wilfred Ngwa, Surbhi Grover, John Longo
There are considerable challenges to meeting the demands of the impending cancer crisis in Africa. These include a rising incidence of cancer and cancer-related deaths, equipment and maintenance costs, and deficits in human resources and training. Addressing these issues would be crucial to tackling the increasing burden of cancer on the continent. Innovations in technology and collaborative efforts within the global oncology community have created promising solutions for establishing quality cancer care in Africa and eradicating the massive disparities that currently exist...
April 2017: Seminars in Radiation Oncology
https://www.readbyqxmd.com/read/28325242/radiation-oncology-in-india-challenges-and-opportunities
#8
REVIEW
Surbhi Grover, Shivakumar Gudi, Ajeet Kumar Gandhi, Priya M Puri, Adam C Olson, Danielle Rodin, Onyi Balogun, Preet K Dhillon, Daya Nand Sharma, Goura Kishor Rath, Shyam Kishore Shrivastava, Akila N Viswanathan, Umesh Mahantshetty
Rising cancer incidence and mortality in India emphasize the need to address the increasing burden of this disease and the stark inequities in access to radiotherapy and other essential medical treatments. State-of-the-art technology is available within the private sector and a few hospitals in the public sector, but 75% of patients in the public sector in India do not have access to timely radiotherapy. This inequity in access to radiotherapy in the public sector is amplified in rural areas, where most of India׳s population lives...
April 2017: Seminars in Radiation Oncology
https://www.readbyqxmd.com/read/28325241/radiation-oncology-in-the-developing-economies-of-central-and-eastern-europe
#9
REVIEW
Natia Esiashvili
Eastern Europe is represented by 22 countries of significant variability in population density and degree of economic development. They have been affected by past geopolitical isolation due to their association with the "Soviet Block." Currently, all Eastern European countries except Slovenia are low- or middle-income level and 10 of them are part of European Union. Health care systems in Central and Eastern Europe have been influenced by the legacy of centralized soviet-era governance; however, most countries, particularly in European Union zone, have gone through health care reforms directed toward modernizing infrastructure and staffing...
April 2017: Seminars in Radiation Oncology
https://www.readbyqxmd.com/read/28323588/virtual-reality-applications-for-stress-management-training-in-the-military
#10
Federica Pallavicini, Luca Argenton, Nicola Toniazzi, Luciana Aceti, Fabrizia Mantovani
INTRODUCTION: Stress Management Training programs are increasingly being adopted in the military field for resilience empowerment and primary stress prevention. In the last several years, advanced technologies (virtual reality in particular) have been integrated in order to develop more innovative and effective stress training programs for military personnel, including soldiers, pilots, and other aircrew professionals. This systematic review describes experimental studies that have been conducted in recent years to test the effectiveness of virtual reality-based Stress Management Training programs developed for military personnel...
December 1, 2016: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28323152/loop-mediated-isothermal-amplification-lamp-a-novel-rapid-detection-platform-for-pathogens
#11
REVIEW
Yanmei Li, Penghui Fan, Shishui Zhou, Li Zhang
Foodborne bacterial infections and diseases have been considered to be a major threat for public health in the worldwide. Increased incidence of human diseases caused by foodborne pathogens have been correlated with growing world population and mobility. Loop-mediated isothermal amplification (LAMP) has been regarded as an innovative gene amplification technology and emerged as an alternative to PCR-based methodologies in both clinical laboratory and food safety testing. Nowadays, LAMP has been applied to detection and identification on pathogens from microbial diseases, as it showed significant advantage in high sensitivity, specificity and rapidity...
March 17, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28323098/an-innovative-method-for-the-preparation-of-high-api-loaded-hollow-spherical-granules-for-use-in-controlled-release-formulation
#12
Takumi Asada, Mitsuaki Kobiki, Yasushi Ochiai, Yasunori Iwao, Shigeru Itai
The aim of this study was to prepare controlled-release (CR) granules with suitable particle strength, flowability, particle size distribution (PSD) and density characteristics for blending with other excipients. We also wanted these CR granules to contain large quantities of active pharmaceutical ingredient (API). A high shear mixer was used to mix an API with various polymers at various feed ratios, and the resulting granulated materials were sprayed with solvent. The wet granules were dried using a fluidized bed dryer to give CR granules...
March 18, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28321561/ethics-and-epistemology-in-big-data-research
#13
Wendy Lipworth, Paul H Mason, Ian Kerridge, John P A Ioannidis
Biomedical innovation and translation are increasingly emphasizing research using "big data." The hope is that big data methods will both speed up research and make its results more applicable to "real-world" patients and health services. While big data research has been embraced by scientists, politicians, industry, and the public, numerous ethical, organizational, and technical/methodological concerns have also been raised. With respect to technical and methodological concerns, there is a view that these will be resolved through sophisticated information technologies, predictive algorithms, and data analysis techniques...
March 20, 2017: Journal of Bioethical Inquiry
https://www.readbyqxmd.com/read/28321265/introducing-the-bone-screw-fastener-for-improved-screw-fixation-in-orthopedic-surgery-a-revolutionary-paradigm-shift
#14
Philip F Stahel, Nicholas A Alfonso, Corey Henderson, Todd Baldini
BACKGROUND: Conventional screws used for fracture fixation in orthopedic surgery continue to rely on the historic buttress thread design. While buttress screws generally provide solid resistance against unidirectional axial loading forces, their design suffers from several limitations, as the buttress thread does not adequately resist multiaxial forces. Furthermore, the buttress screw is prone to stripping at the bone-screw interface and can cause microfracturing of the surrounding bone due to its thread design...
2017: Patient Safety in Surgery
https://www.readbyqxmd.com/read/28320774/3d-bioprint-me-a-socioethical-view-of-bioprinting-human-organs-and-tissues
#15
Niki Vermeulen, Gill Haddow, Tirion Seymour, Alan Faulkner-Jones, Wenmiao Shu
In this article, we review the extant social science and ethical literature on three-dimensional (3D) bioprinting. 3D bioprinting has the potential to be a 'game-changer', printing human organs on demand, no longer necessitating the need for living or deceased human donation or animal transplantation. Although the technology is not yet at the level required to bioprint an entire organ, 3D bioprinting may have a variety of other mid-term and short-term benefits that also have positive ethical consequences, for example, creating alternatives to animal testing, filling a therapeutic need for minors and avoiding species boundary crossing...
March 20, 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/28319764/electrofluid-hydrolysis-enhances-the-production-of-fermentable-sugars-from-corncob-via-in-reverse-phase-induced-voltage
#16
Fengfeng Wu, Yamei Jin, Dandan Li, Yuyi Zhou, Lunan Guo, Mengyue Zhang, Xueming Xu, Na Yang
To improve the economic value of lignocellulosic biomasses, an innovative electrofluidic technology has been applied to the efficient hydrolysis of corncob. The system combines fluidic reactors and induced voltages via magnetoelectric coupling effect. The excitation voltage had a positive impact on reducing sugar content (RSC). But, the increase of voltage frequency at 400-700Hz caused a slight decline of the RSC. Higher temperature limits the electrical effect on the hydrolysis at 70-80°C. The energy efficiency increased under the addition of metallic ions and series of in-phase induced voltage to promote hydrolysis...
March 4, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28319742/biochar-provides-a-safe-and-value-added-solution-for-hyperaccumulating-plant-disposal-a-case-study-of-phytolacca-acinosa-roxb-phytolaccaceae
#17
Shengsen Wang, Bin Gao, Yuncong Li, Yong Sik Ok, Chaofeng Shen, Shengguo Xue
In this work, an innovative approach using biochar technology for hyperaccumulator disposal was developed and evaluated. The heavy metal enriched P. acinosa biomass (PBM) was pyrolyzed to produce biochar (PBC). Both PBM and PBC were characterized with X-ray diffraction (XRD) for crystal phases, scanning electron microscopy (SEM) for surface topography, and analyzed for elemental composition and mobility. The results revealed that whewellite, a dominant crystal form in biomass, was decomposed to calcite after pyrolysis...
February 27, 2017: Chemosphere
https://www.readbyqxmd.com/read/28319050/extracellular-matrix-proteomics-identifies-molecular-signature-of-symptomatic-carotid-plaques
#18
Sarah R Langley, Karin Willeit, Athanasios Didangelos, Ljubica Perisic Matic, Philipp Skroblin, Javier Barallobre-Barreiro, Mariette Lengquist, Gregor Rungger, Alexander Kapustin, Ludmilla Kedenko, Chris Molenaar, Ruifang Lu, Temo Barwari, Gonca Suna, Xiaoke Yin, Bernhard Iglseder, Bernhard Paulweber, Peter Willeit, Joseph Shalhoub, Gerard Pasterkamp, Alun H Davies, Claudia Monaco, Ulf Hedin, Catherine M Shanahan, Johann Willeit, Stefan Kiechl, Manuel Mayr
BACKGROUND: The identification of patients with high-risk atherosclerotic plaques prior to the manifestation of clinical events remains challenging. Recent findings question histology- and imaging-based definitions of the "vulnerable plaque," necessitating an improved approach for predicting onset of symptoms. METHODS: We performed a proteomics comparison of the vascular extracellular matrix and associated molecules in human carotid endarterectomy specimens from 6 symptomatic versus 6 asymptomatic patients to identify a protein signature for high-risk atherosclerotic plaques...
March 20, 2017: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28318400/new-frontiers-in-fibers-innovative-and-emerging-research-on-the-gut-microbiome-and-bone-health
#19
Taylor C Wallace, Massimo Marzorati, Lisa Spence, Connie M Weaver, Patricia S Williamson
The complex interactions between the diet, gut microbiome, and host characteristics that provide a functional benefit to the host are an area of great interest and current exploration in the nutrition and health science community. New technologies are available to assess mechanisms that may explain these functional benefits to the host. One emerging functional benefit from changes in the gut microbiome is increased calcium absorption, increased calcium retention, and improved indices of bone health. Prebiotic fibers enhance microbial fermentation in the gut, providing an ecological advantage to specific nonpathogenic bacteria that have the ability to modify an individual's metabolic potential...
March 20, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28316942/piezosurgery-a-boon-for-modern-periodontics
#20
REVIEW
Mathai Thomas, Uttam Akula, Kranti K R Ealla, Nirosha Gajjada
Dentistry has undergone significant advancement and has seen several changing concepts over a decade. One such novel innovation is piezosurgery. Piezoelectric bone surgery or otherwise known as piezosurgery is a novel technique invented by Professor Vercellotti in 1988 to overcome the limitations of traditional instrumentation in oral bone surgery by modifying and improving conventional ultrasound technology. It is a promising, meticulous, and soft tissue sparing system for bone cutting based on low frequency ultrasonic microvibrations...
January 2017: Journal of International Society of Preventive & Community Dentistry
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