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Martin Hoferichter, Philipp Klos, Javier Menéndez, Achim Schwenk
Searches for invisible Higgs decays at the Large Hadron Collider constrain dark matter Higgs-portal models, where dark matter interacts with the standard model fields via the Higgs boson. While these searches complement dark matter direct-detection experiments, a comparison of the two limits depends on the coupling of the Higgs boson to the nucleons forming the direct-detection nuclear target, typically parametrized in a single quantity f_{N}. We evaluate f_{N} using recent phenomenological and lattice-QCD calculations, and include for the first time the coupling of the Higgs boson to two nucleons via pion-exchange currents...
November 3, 2017: Physical Review Letters
Rebecca A Miksad, Amy P Abernethy
The role of real-world evidence (RWE) in regulatory, drug development, and healthcare decision-making is rapidly expanding. Recent advances have increased the complexity of cancer care and widened the gap between randomized clinical trial (RCT) results and the evidence needed for real-world clinical decisions. Instead of remaining invisible, data from the >95% of cancer patients treated outside of clinical trials can help fill this void.
December 6, 2017: Clinical Pharmacology and Therapeutics
Hee Jun Shin, Min-Cheol Lim, Kisang Park, Sae-Hyung Kim, Sung-Wook Choi, Gyeongsik Ok
We experimentally modulate the refractive index and the absorption coefficient of an SU-8 dry film in the terahertz region by UV light (362 nm) exposure with time dependency. Consequently, the refractive index of SU-8 film is increased by approximately 6% after UV light exposure. Moreover, the absorption coefficient also changes significantly. Using the reflective terahertz imaging technique, in addition, we can read security information printed by UV treatment on an SU-8 film that is transparent in the visible spectrum...
December 6, 2017: Sensors
Carolina Rodrigues da Costa Doria, Simone Athayde, Elineide E Marques, Maria Alice Leite Lima, Jynessa Dutka-Gianelli, Mauro Luis Ruffino, David Kaplan, Carlos E C Freitas, Victoria N Isaac
We analyze the invisibility of fisheries and inadequacy of fishers' participation in the process of hydropower development in the Amazon, focusing on gaps between legally mandated and actual outcomes. Using Ostrom's institutional design principles for assessing common-pool resource management, we selected five case studies from Brazilian Amazonian watersheds to conduct an exploratory comparative case-study analysis. We identify similar problems across basins, including deficiencies in the dam licensing process; critical data gaps; inadequate stakeholder participation; violation of human rights; neglect of fishers' knowledge; lack of organization and representation by fishers' groups; and lack of governmental structure and capacity to manage dam construction activities or support fishers after dam construction...
December 5, 2017: Ambio
André Pornon, Christophe Andalo, Monique Burrus, Nathalie Escaravage
Animal pollination, essential for both ecological services and ecosystem functioning, is threatened by ongoing global changes. New methodologies to decipher their effects on pollinator composition to ecosystem health are urgently required. We compare the main structural parameters of pollination networks based on DNA metabarcoding data with networks based on direct observations of insect visits to plants at three resolution levels. By detecting numerous additional hidden interactions, metabarcoding data largely alters the properties of the pollination networks compared to visit surveys...
December 4, 2017: Scientific Reports
D S Sayi, Surya Mohan, K Vinod Kumar
Fermented product of combination of five major substances obtained from cow, viz., urine, milk, ghee, curd, and dung, is known as Panchagavya. Its pro-agricultural and medicinal value has been traditionally known to Indian farmers from Vedic period. In this study, the proteolytic properties of Panchagavya were investigated using Skim Milk Agar (SMA) form, a commercially available Panchagavya product. Proteolytic bacteria, SNCK-3, was successfully isolated. Further identification using 16s rDNA sequencing revealed that SNCK-3 belonged to Acinetobacter spp...
December 1, 2017: Journal of Ayurveda and Integrative Medicine
Xiao He, Tianzhi Yang, Xingwei Zhang, Linzhi Wu, Xiao Qiao He
The camouflage phenomenon (invisibility or illusion) of thermodynamics has attracted great attentions and many experimental demonstrations have been achieved by virtue of simplified approaches or the scattering cancellation. However, all of the experiments conducted are limited in the invisibility of spheres or two-dimensional (2D) cylinders. An ellipsoid camouflage device with a homogenous and isotropic shell is firstly reported based on the idea of the neutral inclusion and a 2D elliptical thermal camouflage device is realized by a thin-layer cloak of homogeneous isotropic material firstly...
November 30, 2017: Scientific Reports
Song Yang, Jing Wu, Si Lei
RATIONALE AND OBJECTIVE: The computed tomography (CT) features of hepatic veno-occlusive disease (HVOD) could play a role in its diagnosis. We aimed to perform a meta-analysis of studies examining the CT features of HVOD. METHODS: Relevant studies published up to May 3, 2017 were searched in major electronic databases. The extracted data included the proportion of various CT features in patients with HVOD. The meta-analysis was conducted using R 3.3.3 with the "meta" package...
November 27, 2017: Academic Radiology
Mathias Grote
Microbial diversity has become a leitmotiv of contemporary microbiology, as epitomized in the concept of the microbiome, with significant consequences for the classification of microbes. In this paper, I contrast microbiology's current diversity ideal with its influential predecessor in the twentieth century, that of purity, as epitomized in Robert Koch's bacteriological culture methods. Purity and diversity, the two polar opposites with regard to making sense of the microbial world, have been operationalized in microbiological practice by tools such as the "clean" Petri dish versus the "dirty" Winogradsky column, the latter a container that mimics, in the laboratory, the natural environment that teems with diverse microbial life...
November 29, 2017: History and Philosophy of the Life Sciences
Junshan Lin, Dumiao Li, Jinwen Chen, Li Lin, Yali Xu
OBJECTIVE: Open inguinal hernia repair by Bianchi incision is a potential alternative technique for the treatment of IH. This study aims to retrospectively analyze boys with IH, who underwent open IH repair by Bianchi incision. METHODS: A total of 3300 boys (1-144 months) with IH from April 2007 to September 2015 were enrolled into this study. An open high scrotal incision (Bianchi incision) to ligate the processus proximal to the internal inguinal ring was performed in patients for IH repair...
November 29, 2017: Pediatric Surgery International
Jean K Marshall, Noel Tait, Jan van der Linden
INTRODUCTION: Avoiding tissue desiccation is a common recommendation to reduce postoperative complications following open abdominal surgery, although difficult to achieve delicately without damaging the peritoneal mesothelium. Insufflation of humidified-warm CO2 into the abdomen during open abdominal surgery is proposed as an invisible, effortless way to prevent desiccation. We hypothesized that desiccation during open abdominal surgery would cause loss of peritoneal mesothelium that would be prevented by insufflation of humidified-warm CO2...
December 2017: Journal of Surgical Research
Søren Roi Midtgaard, Tamim A Darwish, Martin Cramer Pedersen, Pie Huda, Andreas Haahr Larsen, Grethe Vestergaard Jensen, Søren Andreas Røssel Kynde, Nicholas Skar-Gislinge, Agnieszka Janina Zygadlo Nielsen, Claus Olesen, Mickael Blaise, Jerzy Józef Dorosz, Thor Seneca Thorsen, Raminta Venskutonytė, Christian Krintel, Jesper V Møller, Henrich Frielinghaus, Elliot Paul Gilbert, Anne Martel, Jette Sandholm Kastrup, Poul Erik Jensen, Poul Nissen, Lise Arleth
A novel and generally applicable method for determining structures of membrane proteins in solution via small-angle neutron scattering (SANS) is presented. Common detergents for solubilizing membrane proteins were synthesized in isotope-substituted versions for utilizing the intrinsic neutron scattering length difference between hydrogen and deuterium. Individual hydrogen/deuterium levels of the detergent head and tail groups were achieved such that the formed micelles became effectively invisible in heavy water (D2 O) when investigated by neutrons...
November 27, 2017: FEBS Journal
(no author information available yet)
No abstract text is available yet for this article.
December 2017: Journal of the American Academy of Child and Adolescent Psychiatry
Anna Gregory, Shylie Mackintosh, Saravana Kumar, Carol Grech
INTRODUCTION: Problems experienced by older people with complex needs to live at home have been reported in the literature. This qualitative study builds on previous research and investigates enduring issues older people face when interacting with healthcare services. AIM: To gain an in-depth understanding of what is involved in providing good quality health care for older people who need support to live at home. METHODOLOGICAL DESIGN: We adopted an interpretive descriptive approach and conducted semi-structured interviews with older people (n = 7), carers (n = 8) and key informants (n = 11)...
November 24, 2017: Scandinavian Journal of Caring Sciences
Frederick J Zimmerman
The ethical principle of autonomy is among the most fundamental in ethics, and it is particularly salient for those in public health, who must constantly balance the desire to improve health outcomes by changing behavior with respect for individual freedom. Although there are some areas in which there is a genuine tension between public health and autonomy-childhood vaccine mandates, for example-there are many more areas where not only is there no tension, but public health and autonomy come down to the same thing...
November 2017: Hastings Center Report
Johannes Wolf, Norman Haendel, Johannes Remmler, Carl Elias Kutzner, Thorsten Kaiser, Thomas Mothes
BACKGROUND: Antibodies against tissue transglutaminase (TTG) of isotype IgA (IgA-aTTG) represent reliable diagnostic markers to confirm or exclude celiac disease (CD). Hemolysis (HL) is an important pre-analytical factor. HL can be quantified as HL index (HI) correlating with the concentration of free hemoglobin. TTG is abundant in erythrocytes and released upon HL. In immunoassays, the released TTG may interfere with binding of IgA-aTTG to the coated TTG. METHODS: We selected 17 HL-free sera from children with biopsy-confirmed CD: 7 with low-positive (1-5 multiples of upper limit of normal [×ULN]), 5 with intermediate (5-10 × ULN) and 5 with high IgA-aTTG (10-15 × ULN)...
November 23, 2017: Journal of Clinical Laboratory Analysis
Jian Li, Shao-Ju Guo, Jing-Chao Zhang, Hong-Yan Wang, Kai Li, She-Hui Niu
OBJECTIVES: Large impacted or residual invisible common bile duct (CBD) stones after mechanical lithotripsy are challenging. We aimed to evaluate the feasibility and success rate of a new hybrid anchoring balloon-guided direct peroral cholangioscopy (POC) for these conditions, using an ultraslim endoscope. METHODS: Sixty-five patients with large or residual invisible CBD stones for direct POC from July 2012 to July 2016 were identified, including 6 cases in whom an additional interventional procedure was required...
November 23, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
Donna Carlyle
This paper discusses the merits of pluralism in practice. It argues for a wider recognition of creative and integrative approaches, such as those used in the field of children's geographies (involving places and spaces), as a way of unlocking practitioner potential and innovation. By re-thinking child and human development, viewing it as socially, culturally and philosophically bound, through the proposed concept of 'vectors of entanglements', the author seeks to demonstrate and encourage the application of hybrid approaches across multi-disciplinary fields...
2017: International Journal for the Advancement of Counseling
Shihan Sajeed, Carter Minshull, Nitin Jain, Vadim Makarov
A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper.
November 22, 2017: Scientific Reports
Alexander Baade, Claus von der Burchard, Meike Lawin, Stefan Koinzer, Benedikt Schmarbeck, Kerstin Schlott, Yoko Miura, Johann Roider, Reginald Birngruber, Ralf Brinkmann
Laser photocoagulation has been a treatment method for retinal diseases for decades. Recently, studies have demonstrated therapeutic benefits for subvisible effects. A treatment mode based on an automatic feedback algorithm to reliably generate subvisible and visible irradiations within a constant irradiation time is introduced. The method uses a site-individual adaptation of the laser power by monitoring the retinal temperature rise during the treatment using optoacoustics. This provides feedback to adjust the therapy laser power during the irradiation...
November 2017: Journal of Biomedical Optics
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