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Saloua Berdai Chaouni, Liesbeth De Donder
The number of older Moroccan migrants reaching the age of high risk for dementia is increasing in Belgium. Yet no study has been performed to explore how Moroccan families facing dementia experience and manage the condition. The study employed a qualitative design using semi-structured interviews with 12 informal and 13 formal caregivers to answer this research question. Findings indicate that the experience of dementia includes several invisible realities that challenge the informal and formal caregivers: (1) the invisibility of dementia as a condition; (2) the invisible subtleties of the informal care execution; (3) the invisibility and inaccessibility of care services as explanation for these family's non-use of available services; and (4) the overlooking of culture, migration and religion as invisible influencers of the overall dementia experience...
January 1, 2018: Dementia
Wyona M Freysteinson, Susan Mellott, Tania Celia, Jinlan Du, Marilyn Goff, Tana Plescher, Zoheb Allam
The researchers were invited to a transitional home for homeless women veterans to help veterans with body image issues. Convenience sampling was used to recruit 12 veterans who perceived they had a physical difference due to military service. Data were obtained in focus groups where the veterans were invited to share stories. Ricoeur's hermeneutic phenomenology guided the study. The research team learned early in the data collection stage that 11 of the 12 participants suffered military sexual trauma (MST)...
April 12, 2018: Issues in Mental Health Nursing
Xin Guo, Xue-Mei Wang, Shuai Wei, Shou-Jun Xiao
Design rules for DNA nanotechnology have been mostly learnt from using linear single stranded (ss) DNAs as the source materials. For example, a typical DAO (Double crossover, Antiparallel, Odd half turns) tile for assembling two-dimensional (2D) lattices is built by only two linear ss-oligonucleotide scaffold strands, like two ropes making a square knot. We demonstrate here a new type of coupled DAO (cDAO) tiles and their 2D lattices using small circular ss-oligonucleotides as scaffold strands and linear ss-oligonucleotides as staple strands...
April 12, 2018: Chembiochem: a European Journal of Chemical Biology
Rosemary Aldrich
No abstract text is available yet for this article.
April 16, 2018: Medical Journal of Australia
Paul Willis, Kathryn Almack, Trish Hafford-Letchfield, Paul Simpson, Barbara Billings, Naresh Mall
Background : Older lesbian, gay, bisexual and trans (LGBT) residents are often invisible in long-term care settings. This article presents findings from a community-based action research project, which attempted to address this invisibility through co-produced research with LGBT community members. Particular Question: What conditions enable co-produced research to emerge in long-term residential care settings for older people? Aims of Project: To analyse outcomes and challenges of action-oriented, co-produced research in the given context...
April 7, 2018: International Journal of Environmental Research and Public Health
Koen A Marijt, Elien M Doorduijn, Thorbald van Hall
T-cell based immunotherapies through checkpoint blockade or adoptive transfer are effective treatments for a wide range of cancers like melanomas and lung carcinomas that harbor a high mutational load. The HLA class I and class II (HLA-I and HLA-II) presented neoantigens arise from genetic mutations in the cancerous cells and are ideal non-self targets for the T cell-based treatments. Although some cancer patients responded with complete regression, many others are irresponsive to checkpoint blockade treatments, or relapse after initial success...
April 4, 2018: Molecular Immunology
Susan T Crowley, Katherine Murphy
Just as the "New Deal" aimed to elevate the "forgotten man" of the Great Depression through governmental relief and reform, so does the Department of Veterans Affairs (VA) health care system aim to improve the health of veterans with the invisible illness of chronic kidney disease through a concerted series of health care delivery reforms. Augmenting its primary care platform with advances in informatics and health service delivery initiatives targeting kidney disease, the VA is changing how nephrology care is provided to veterans with the goal of optimized population kidney health...
April 4, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
Shenhao Dai, Klaus Dieterich, Marie Jaeger, Bernard Wuyam, Pierre-Simon Jouk, Dominic Pérennou
OBJECTIVE: To understand the disability of adults with arthrogryposis multiplex congenita (AMC), a rare disease spectrum characterized by at least 2 joint contractures at birth in different body areas. METHODS: This is a retrospective analysis of data for unselected persons with AMC referred to the French center for adults with AMC from 2010 to 2016. All underwent a pluriprofessional systematic and comprehensive investigation of deficits, activity limitation, and participation restriction according to the International Classification of Functioning, Disability and Health and genetic analysis when indicated...
April 6, 2018: Neurology
Marc M Lauffs, Oh-Hyeon Choung, Haluk Öğmen, Michael H Herzog
Unconscious visual stimuli can affect conscious perception: For example, an invisible prime can affect responses to a subsequent target. The invisible interpretation of an ambiguous figure can have similar effects. Invisibility in these situations is typically explained by stimulus-suppression in early, retinotopic brain areas. We have previously argued that invisibility is closely linked to Gestalt ("object") organization principles. For example, motion is typically perceived in non-retinotopic, object-centered, and not in retinotopic coordinates...
April 4, 2018: Consciousness and Cognition
Shanon Peter
No abstract text is available yet for this article.
April 2, 2018: American Journal of Medicine
Chen Xie, Xu Zhen, Qingqing Miao, Yan Lyu, Kanyi Pu
Detection of metastatic tumor tissues is crucial for cancer therapy; however, fluorescence agents that allow to do share the disadvantage of low signal-to-background ratio due to tissue autofluorescence. The development of amphiphilic poly(p-phenylenevinylene) derivatives that can self-assemble into the nanoagent (SPPVN) in biological solutions and emit near-infrared afterglow luminescence after cessation of light irradiation for ultrasensitive imaging of metastatic tumors in living mice is herein reported...
April 2, 2018: Advanced Materials
Q Chen, H Du, C Wang, J L Tang, R F Wu
Objective: To explore the human papilomavirus (HPV) genotypes and epithelial thickness of invisible cervical intraepithelial neoplasia Ⅲ (CIN Ⅲ) under colposcopy. Methods: One hundred and sixty-nine biopsies from 93 patients with a final diagnosis of CIN Ⅲ were extracted from the Shenzhen cervical cancer screening trial Ⅱ (SHENCCAST Ⅱ) . The SHENCCAST Ⅱ was conducted from 2009 to 2010. All the cervical blocks from these patients were re-cut and placed on 6 slides, i.e. sandwich model, with the top and bottom sections being stained with HE, the top second be processed for other studies, 3 sections for HPV genotypes by matrix-assisted laser desorption ionization-time of flight-mass spectrometry (MALDI-TOF-MS) assay...
March 25, 2018: Zhonghua Fu Chan Ke za Zhi
Jiacheng Chen, Yifan Chen, Ying Liu
The relationship between consciousness and feature binding has long been a topic of debate. Although they may be associated, there is growing evidence supporting the notion that feature binding and visual consciousness can be separated to some degree. In our study, we manipulated the visibility of priming stimuli, which consisted of color-motion features, and then measured the effects of those manipulations on reporting of cued targets' direction of rotation. A priming effect was observed even when the priming stimuli were invisible, implying that the color-motion features of the prime could bind unconsciously...
March 28, 2018: Neuroscience Letters
Amithavikram R Hathibelagal, Beatrix Feigl, Andrew J Zele
This study investigated how invisible extrinsic temporal white noise that correlates with the activity of one of the three [magnocellular (MC), parvocellular (PC), or koniocellular (KC)] post-receptoral pathways alters mesopic rod signaling. A four-primary photostimulator provided independent control of the rod and three cone photoreceptor excitations. The rod contributions to the three post-receptoral pathways were estimated by perceptually matching a 20% contrast rod pulse by independently varying the LMS (MC pathway), +L-M (PC pathway), and S-cone (KC pathway) excitations...
April 1, 2018: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
Lodd Mahendra
The trend of clinical orthodontics has shown a palpable shift from conventional braces to innovative technologies like invisible aligners. Aligners are sequences of clear trays worn by patients to straighten their teeth. They were envisaged for the main purpose of esthetics, mainly directed toward self-conscious teenagers who otherwise would shy away from essential correction of malocclusion.
March 1, 2018: Journal of Contemporary Dental Practice
Hailey M Brown, Scott B Biering, Allen Zhu, Jayoung Choi, Seungmin Hwang
A hallmark of positive-sense RNA viruses is the formation of membranous shelters for safe replication in the cytoplasm. Once considered invisible to the immune system, these viral shelters are now found to be antagonized through the cooperation of autophagy proteins and anti-microbial GTPases. This coordinated effort of autophagy proteins guiding GTPases functions against not only the shelters of viruses but also cytoplasmic vacuoles containing bacteria or protozoa, suggesting a broad immune-defense mechanism against disparate vacuolar pathogens...
March 30, 2018: BioEssays: News and Reviews in Molecular, Cellular and Developmental Biology
A M Bakker, G H E J Vijgen, N G Hartwig, G A Tramper-Stranders
Acute lobar nephritis (ALN) is a focal interstitial bacterial infection of the renal parenchyma. ALN is described as a midpoint between an acute pyelonephritis and renal abscess. ALN is underdiagnosed in children due to both non-specific symptoms and negative urinalysis/bacteriuria laboratory findings. The gold standard for diagnosis of ALN is CT scanning, however MRI can be considered to avoid radiation exposure. Diagnosing ALN is relevant, because it requires prolonged antibiotic treatment. Insufficient antibiotic treatment could cause renal scarring and subsequent hypertension or renal failure...
2018: Nederlands Tijdschrift Voor Geneeskunde
Paula T Ross, Monica L Lypson
BACKGROUND: Veterans have unique experiences that warrant special consideration in health care. Unfortunately, training in veteran-centred care has not been a clear focus of medical education, and only a very small proportion of medical schools include military cultural competency in their curricula. METHODS: We conducted an 80-minute focus group with six US veterans. Open-ended questions were used to elicit their perceptions of the health care that they receive, and how it can be improved...
March 30, 2018: Clinical Teacher
Jiachao Liu, Susannah M Dorfman, Feng Zhu, Jie Li, Yonggang Wang, Dongzhou Zhang, Yuming Xiao, Wenli Bi, E Ercan Alp
Heterogeneity in Earth's mantle is a record of chemical and dynamic processes over Earth's history. The geophysical signatures of heterogeneity can only be interpreted with quantitative constraints on effects of major elements such as iron on physical properties including density, compressibility, and electrical conductivity. However, deconvolution of the effects of multiple valence and spin states of iron in bridgmanite (Bdg), the most abundant mineral in the lower mantle, has been challenging. Here we show through a study of a ferric-iron-only (Mg0...
March 29, 2018: Nature Communications
Eui Jin Hwang, Hyungjin Kim, Chang Min Park, Soon Ho Yoon, Hyun-Ju Lim, Jin Mo Goo
OBJECTIVE: To evaluate the impact of nodule visibility during real-time fluoroscopy and other biopsy-related variables on the diagnostic accuracy and complication rates of cone-beam computed tomography (CBCT) virtual navigation (VN)-guided percutaneous transthoracic needle biopsies (PTNBs) of small (≤ 1cm) pulmonary nodules. METHODS: Patients (99 males and 114 females; age, 62.1 ± 11.1 years) who underwent CBCT VN-guided biopsies for lung nodules ≤ 1 cm were retrospectively reviewed...
March 29, 2018: British Journal of Radiology
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