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https://www.readbyqxmd.com/read/28934768/cutaneous-melanoma-an-audit-of-management-timeliness-against-new-zealand-guidelines
#1
Tess Brian, Brandon Adams, Michael Jameson
AIM: The New Zealand Ministry of Health's "Faster Cancer Treatment" programme aims for timely care for patients with cancer, including melanoma. Melanoma care guidelines detail investigation and treatment timeliness standards. This audit assesses compliance with these. METHOD: Patients admitted to Waikato Hospital for melanoma surgery during the year ending February 2016 were retrospectively identified. Time intervals between care events were calculated. Demographic, lesion, surgical and histopathological characteristics were analysed...
September 22, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/28934326/the-effect-of-electronic-health-record-software-design-on-resident-documentation-and-compliance-with-evidence-based-medicine
#2
Yasaira Rodriguez Torres, Jordan Huang, Melanie Mihlstin, Mark S Juzych, Heidi Kromrei, Frank S Hwang
This study aimed to determine the role of electronic health record software in resident education by evaluating documentation of 30 elements extracted from the American Academy of Ophthalmology Dry Eye Syndrome Preferred Practice Pattern. The Kresge Eye Institute transitioned to using electronic health record software in June 2013. We evaluated the charts of 331 patients examined in the resident ophthalmology clinic between September 1, 2011, and March 31, 2014, for an initial evaluation for dry eye syndrome...
2017: PloS One
https://www.readbyqxmd.com/read/28933336/bioavailability-of-oxycodone-after-administration-of-a-new-prolonged-release-once-daily-tablet-formulation-in-healthy-subjects-in-comparison-to-an-established-twice-daily-tablet%C3%A2
#3
Bernhard Scheidel, Martina A Maritz, Yves J Gschwind, Kerstin Steigerwald, Volker Guth, Peter Kovacs, Helene Rey
OBJECTIVE: To evaluate and to compare the bioavailability, the influence of food intake on the bioavailability, and the safety and tolerability of a newly-developed oxycodone once-daily (OOD) prolonged-release tablet with an established oxycodone twice-daily (OTD) prolonged-release tablet after single-dose administration under fasting or fed conditions as well as after multiple-dose administration. MATERIALS AND METHODS: Three single-center, open-label, randomized, balanced, two-treatment, two-period, two-sequence crossover studies were conducted...
September 21, 2017: International Journal of Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28933273/microsponge-embedded-tablet-for-sustained-delivery-of-nifedipine
#4
Indu Pal Kaur, Rakesh Tekade
BACKGROUND: Nifedipine is a potential therapeutic agent for the treatment of cardiovascular disturbances, although it suffers from short half-life (t1/2, 2 hr). OBJECTIVE: To address the problem, we first prepared nifedipine loaded sustained releases microsponges and then formulated tablets for effective clinical application and patient compliance. METHOD: Preparations of microsponges were carried out using different composition of nifedipine and polymer (1:1, 1:2 and 1:3 % molar ratio) using emulsion solvent diffusion technique...
September 21, 2017: Pharmaceutical Nanotechnology
https://www.readbyqxmd.com/read/28932728/laparoscopic-gastrojejunostomy-versus-duodenal-stenting-in-unresectable-gastric-cancer-with-gastric-outlet-obstruction
#5
Sa-Hong Min, Sang-Yong Son, Do-Hyun Jung, Chang-Min Lee, Sang-Hoon Ahn, Do Joong Park, Hyung-Ho Kim
PURPOSE: To compare the outcome between laparoscopic gastrojejunostomy (LapGJ) and duodenal stenting (DS) in terms of oral intake, nutritional status, patency duration, effect on chemotherapy and survival. METHODS: Medical records of 115 patients, who had LapGJ or duodenal stent placement between July 2005 and September 2015 in Seoul National University Bundang Hospital, have been reviewed retrospectively. Oral intake was measured with Gastric Outlet Obstruction Scoring System...
September 2017: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/28932494/nanotechnology-advancing-the-translational-respiratory-research
#6
Kamal Dua, Shakti Dhar Shukla, Terezinha de Jesus Andreoli Pinto, Philip Michael Hansbro
Considering the various limitations associated with the conventional dosage forms, nanotechnology is gaining increased attention in drug delivery particularly in respiratory medicine and research because of its advantages like targeting effects, improved pharmacotherapy, and patient compliance. This paper provides a quick snapshot about the recent trends and applications of nanotechnology to various translational and formulation scientists working on various respiratory diseases, which can help paving a new path in developing effective drug delivery system...
March 2017: Interventional Medicine & Applied Science
https://www.readbyqxmd.com/read/28932312/indicators-of-asthma-control-in-asthmatic-patients-are-they-related-to-depression
#7
Tarig H Merghani, Azza O Alawad
BACKGROUND: Many patients with chronic illnesses suffer from depression. A poorly controlled asthma that presents with repeated attacks of breathlessness is a recognised risk factor for bipolar disorders. On the other hand, depression can aggravate asthma symptoms. AIM: The aim of this study is to determine the indicators of the asthma control test (ACT) among the asthmatic patients who attend the outpatient clinic for follow-up and to investigate the relation between these indicators and clinical depression, using a standardised depression scale...
August 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28932161/the-efficacy-of-a-diabetic-educational-program-and-predictors-of-compliance-of-patients-with-noninsulin-dependent-type-2-diabetes-mellitus-in-al-khobar-saudi-arabia
#8
Fatma M Mokabel, Shadia F Aboulazm, Hanan E Hassan, Mona F Al-Qahtani, Seham F Alrashedi, Fatma A Zainuddin
BACKGROUND: The concept of detection and management of diabetes mellitus at primary health-care centers is justified and widely practised in Saudi Arabia. The objective of this study was to assess the efficacy of diabetic educational programs for noninsulin-dependent (type 2) diabetes mellitus patients, and to determine the predictors of compliance. MATERIALS AND METHODS: A longitudinal experimental research design was adopted for this study and conducted at the diabetic outpatient clinic of King Fahd Hospital of the University, Al Khobar, Kingdom of Saudi Arabia...
September 2017: Journal of Family & Community Medicine
https://www.readbyqxmd.com/read/28932091/randomized-clinical-trial-comparing-fixed-time-split-dosing-and-split-dosing-of-oral-picosulfate-regimen-for-bowel-preparation
#9
Jae Hyuck Jun, Koon Hee Han, Jong Kyu Park, Hyun Il Seo, Young Don Kim, Sang Jin Lee, Baek Gyu Jun, Min Sik Hwang, Yoon Kyoo Park, Myeong Jong Kim, Gab Jin Cheon
AIM: To compare the efficacy of fixed-time split dose and split dose of an oral sodium picosulfate for bowel preparation. METHODS: This is study was prospective, randomized controlled study performed at a single Institution (2013-058). A total of 204 subjects were assigned to receive one of two sodium picosulfate regimens (i.e., fixed-time split or split) prior to colonoscopy. Main outcome measurements were bowel preparation quality and subject tolerability. RESULTS: There was no statistical difference between the fixed-time split dose regimen group and the split dose regimen group (Ottawa score mean 2...
August 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28931943/vagus-nerve-stimulation-paired-with-tones-for-the-treatment-of-tinnitus-a-prospective-randomized-double-blind-controlled-pilot-study-in-humans
#10
Richard Tyler, Anthony Cacace, Christina Stocking, Brent Tarver, Navzer Engineer, Jeffrey Martin, Aniruddha Deshpande, Nancy Stecker, Melissa Pereira, Michael Kilgard, Chester Burress, David Pierce, Robert Rennaker, Sven Vanneste
The aim of the pilot study was to evaluate the effect of Vagus Nerve Stimulation (VNS) paired with sounds in chronic tinnitus patients. All participants were implanted and randomized to a paired VNS (n = 16) or control (n = 14) group. After 6 weeks of home therapy, all participants received paired VNS. The device was used on 96% of days with good compliance. After 6 weeks, the paired VNS group improved on the Tinnitus Handicap Inventory (THI) (p = 0.0012) compared to controls (p = 0.1561). The between-group difference was 10...
September 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28931356/menopause-a-complex-and-controversial-journey
#11
Salam Chalouhi
Menopause is defined as permanent cessation of menstrual periods, determined retrospectively after a woman has experienced 12 months of amenorrhea without any other obvious cause. Over the years, the discourse surrounding the Climacteric was mainly elicited as a "disease of the castrates", as opposed to the feminist views. There has been a large feminist contribution to both the debate of contraception and menopause in the last few years. Over the years, menopause has been treated in a uniform fashion, as a disease, excluding the different circumstances and lived experiences that patients go through during this sensitive period...
September 2017: Post Reproductive Health
https://www.readbyqxmd.com/read/28930780/splinting-after-ear-reconstruction-a-stepwise-and-inexpensive-workflow-protocol
#12
Herman Vercruysse, James I J Green, Gaynor Osman, Brigitte Harrison, Kana Miyagi, Neil W Bulstrode
BACKGROUND: Long-term postoperative splinting plays a role in the prevention of contracture of the grafted skin after a second-stage ear reconstruction. The scar retraction could lead to an unfavorable aesthetic outcome. Splinting could play a role to overcome or prevent the loss of projection and the obliteration of the sulcus. MATERIAL AND METHODS: We have defined the characteristics of an ideal long-term splint and present a stepwise clinical protocol for the fabrication of an ethylene-vinyl acetate splint...
September 19, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28929694/-methodological-quality-evaluation-of-randomized-controlled-trials-for-traditional-chinese-medicines-for-treatment-of-sub-health
#13
Jun Zhao, Xing Liao, Hui Zhao, Zhi-Geng Li, Nan-Yue Wang, Li-Min Wang
To evaluate the methodological quality of the randomized controlled trials(RCTs) for traditional Chinese medicines for treatment of sub-health, in order to provide a scientific basis for the improvement of clinical trials and systematic review. Such databases as CNKI, CBM, VIP, Wanfang, EMbase, Medline, Clinical Trials, Web of Science and Cochrane Library were searched for RCTS for traditional Chinese medicines for treatment of sub-health between the time of establishment and February 29, 2016. Cochrane Handbook 5...
November 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28929609/benchmarking-against-the-national-emergency-laparotomy-audit-recommendations
#14
Yiu Ming Ho, Julie Cappello, Ramin Kousary, Brian McGowan, Arkadiusz P Wysocki
BACKGROUND: The Royal College of Anaesthetists published the National Emergency Laparotomy Audit (NELA) to describe and compare inpatient care and outcomes of major emergency abdominal surgery in England and Wales in 2015 and 2016. The purpose of this article is to compare emergency abdominal surgical care and mortality in a regional hospital (Logan Hospital, Queensland, Australia) with NELA results. METHODS: Data were extracted from two databases. All deaths from May 2010 to April 2015 were reviewed and patients who had an emergency abdominal operation within 30 days of death were identified...
September 19, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28929402/characteristics-of-laws-requiring-physicians-to-report-patient-information-for-public-health-surveillance-notable-patterns-from-a-nevada-case-study
#15
Maxim Gakh, Brian Labus, Brittany Walker
Laws across the globe require healthcare providers to disclose patient health information to public health entities for surveillance and intervention purposes. Physicians play a unique role in such mandatory reporting regimes. However, research reveals consistent under-reporting and points to limited knowledge of mandates, perceived burdens of reporting, misaligned incentives and penalties, and a lack of streamlined processes as significant reporting barriers. These barriers suggest that how legal mandates are structured may impact compliance; yet little research systematically examines their characteristics...
September 19, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/28928768/the-effectiveness-of-personalized-bowel-preparation-using-a-smartphone-camera-application-a-randomized-pilot-study
#16
Jae Won Jung, Jongha Park, Gi Jung Jeon, Young Soo Moon, Sung Yuon Yang, Tae Oh Kim, Eui Tay Jung, Hee-Cheol Kim
BACKGROUND: We aimed to investigate the effectiveness of a smartphone application that analyzes and judges the optimal dosage of polyethylene glycol (PEG) for bowel preparation. METHODS: Patients were assigned to use the smartphone camera application (app group) or written instructions (non-app group). The smartphone camera application was programmed to analyze the bowel preparation quality and automatically determine the dosage of PEG from an analysis of stool images...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28928631/glaucoma-biological-trabecular-and-neuroretinal-pathology-with-perspectives-of-therapy-innovation-and-preventive-diagnosis
#17
REVIEW
Raffaele Nuzzi, Federico Tridico
Glaucoma is a common degenerative disease affecting retinal ganglion cells (RGC) and optic nerve axons, with progressive and chronic course. It is one of the most important reasons of social blindness in industrialized countries. Glaucoma can lead to the development of irreversible visual field loss, if not treated. Diagnosis may be difficult due to lack of symptoms in early stages of disease. In many cases, when patients arrive at clinical evaluation, a severe neuronal damage may have already occurred. In recent years, newer perspective in glaucoma treatment have emerged...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28928026/an-online-resource-to-promote-vocational-interests-among-job-seekers-with-multiple-sclerosis-a-randomized-controlled-trial-in-australia
#18
Diana Dorstyn, Rachel Roberts, Gregory Murphy, Ian Kneebone, Ashley Craig, Christine Migliorini
OBJECTIVE: To provide a preliminary evaluation of the effectiveness of an on-line resource for job-seekers with multiple sclerosis. DESIGN: Randomized controlled design. SETTING: Community-dwelling cohort in Australia. PARTICIPANTS: Forty-seven adults with relapsing-remitting or progressive MS accessed an email-delivered, 7-module resource - 'Work and MS' - over a 4-week period. Fifty wait-list control participants were offered the opportunity to access 'Work and MS' 4 weeks post-enrolment...
September 16, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28927491/effectiveness-of-intranasal-sodium-hyaluronate-in-mitigating-adverse-effects-of-nasal-continuous-positive-airway-pressure-therapy
#19
(no author information available yet)
BACKGROUND: Nasal continuous positive airway pressure (CPAP) in moderate-to-severe cases of obstructive sleep apnea cancause nasal discomfort and other undesirable problems. OBJECTIVE: The aim of our study was to test the effects of sodium hyaluronate on nasal problems that patients experienced in their daily lives, sleepiness, nasal resistance to airflow, nasal mucociliary clearance, changes in inflammatory markers, and compliance to CPAP in three groups of patients with obstructive sleep apnea syndrome on CPAP therapy...
September 19, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/28927481/a-system-wide-solution-to-antidote-stocking-in-emergency-departments-the-nova-scotia-antidote-program
#20
Nancy G Murphy, D Ruth Bona, Theresa A Hurley
OBJECTIVE: Inadequate stocking of essential antidotes in hospitals is an internationally documented problem. A concrete and sustainable system-wide solution for easy access to antidotes in emergency departments (EDs) was developed and implemented in Nova Scotia, Canada. METHODS: Antidote stocking guidelines and a systemwide antidote management strategy were established. A standardized collection of antidotes housed in highly visible containers in provincial EDs was implemented for timely access...
September 20, 2017: CJEM
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