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Dnyandeo Pawar, B V Bhaskara Rao, S N Kale
A porous graphene-coated optical fiber Fabry-Perot interferometer (G-FPI) and Fe3O4-graphene nanocomposite coated Fabry-Perot interferometer (FG-FPI) have been investigated and compared for the detection of ammonia gas at room temperature. The sensor probes were subjected to ammonia concentrations varying from 1.5 ppm to 150 ppm. An increased sensitivity was observed for FG-FPI (36 pm ppm-1) when compared with that of G-FPI (25 pm ppm-1). The observed sensor detection limits for FG-FPI and G-FPI were around 7 and 10 ppb, respectively...
March 21, 2018: Analyst
Dunja Šamec, Branimir Urlić, Branka Salopek-Sondi
Kale (Brassica oleracea var. acephala) is a cruciferous vegetable, characterized by leaves along the stem, which, in recent years, have gained a great popularity as a ´superfood´. Consequently, in a popular culture it is listed in many ´lists of the healthiest vegetables´. Without the doubt, a scientific evidence support the fact that cruciferous vegetables included in human diet can positively affect health and well-being, but remains unclear why kale is declared superior in comparison with other cruciferous...
March 20, 2018: Critical Reviews in Food Science and Nutrition
Donovan T Maust, H Myra Kim, Claire Chiang, Helen C Kales
Importance: The Centers for Medicare & Medicaid Services' National Partnership to Improve Dementia Care in Nursing Homes (hereafter referred to as the partnership) was established to improve the quality of care for patients with dementia, measured by the rate of antipsychotic prescribing. Objective: To determine the association of the partnership with trends in prescribing of antipsychotic and other psychotropic medication among older adults in long-term care...
March 17, 2018: JAMA Internal Medicine
Fabien Bernard, Sylvain Dumez, Sébastien Lemière, Anne Platel, Fabrice Nesslany, Annabelle Deram, Franck Vandenbulcke, Damien Cuny
Cadmium (Cd) is a highly toxic element for living organisms and is widespread in metal-contaminated soils. As organisms which can grow up on these polluted areas, plants have some protection mechanisms against Cd issues. Among the plant kingdom, the Brassicaceae family includes species which are known to be able to tolerate and accumulate Cd in their tissues. In this study, Brassica oleracea var. viridis cv "Prover" was exposed to a range of artificially Cd-contaminated soils (from 2.5 up to 20 mg kg-1 ) during 3, 10, and 56 days and the effects on life traits, photosynthesis activity, antioxidant enzymatic activities were studied...
March 15, 2018: Environmental Science and Pollution Research International
Theodore W Kurtz, Stephen E DiCarlo, Michal Pravenec, R Curtis Morris
High salt intake is one of the major dietary determinants of hypertension and cardiovascular disease in Japan and throughout the world. Although dietary salt restriction may be of clinical benefit in salt-sensitive individuals, many individuals may not wish, or be able to, reduce their intake of salt. Thus, identification of functional foods that can help protect against mechanistic abnormalities mediating salt-induced hypertension is an issue of considerable medical and scientific interest. According to the "vasodysfunction" theory of salt-induced hypertension, the hemodynamic abnormality initiating salt-induced increases in blood pressure usually involves subnormal vasodilation and abnormally increased vascular resistance in response to increased salt intake...
March 12, 2018: Journal of Cardiology
Courtney A Polenick, Helen C Kales, Kira S Birditt
Background: Greater feelings of purpose in life are associated with better health and may reduce the negative impact of chronic stress. Yet little is known about how purpose in life may buffer the negative effects of caregiving, a common chronic stressor in middle and later life. Methods: This cross-sectional study utilized a U.S. sample of 315 spousal caregivers and their partners with functional disability drawn from the 2011 National Health and Aging Trends Study and National Study of Caregiving to examine how both parties' perceptions of purpose in life are associated with caregivers' emotional and physical caregiving difficulties...
January 5, 2018: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
Tregei Starr, Timothy J Bauler, Preeti Malik-Kale, Olivia Steele-Mortimer
THP-1 cells differentiated with phorbol 12-myristate 13-acetate (PMA) are widely used as a model for function and biology of human macrophages. However, the conditions used for differentiation, particularly the concentration of PMA and the duration of treatment, vary widely. Here we compare several differentiation conditions and compare the ability of THP-1 macrophages to interact with the facultative intracellular pathogen Salmonella enterica serovar Typhimurium. The results show that THP-1 macrophages differentiated in high concentrations of PMA rapidly died following infection whereas those differentiated in low concentrations of PMA survived and were able to control the intracellular bacteria similar to primary human macrophages...
2018: PloS One
John R Horton, Xu Liu, Lizhen Wu, Kai Zhang, John Shanks, Xing Zhang, Ganesha Rai, Bryan T Mott, Daniel J Jansen, Stephen C Kales, Mark J Henderson, Katherine Pohida, Yuhong Fang, Xin Hu, Ajit Jadhav, David J Maloney, Matthew D Hall, Anton Simeonov, Haian Fu, Paula M Vertino, Qin Yan, Xiaodong Cheng
Isomers of chiral drugs can exhibit marked differences in biological activities. We studied the binding and inhibitory activities of 12 compounds against KDM5A. Among them are two pairs of enantiomers representing two distinct inhibitor chemotypes, namely (R)- and (S)-2-((2-chlorophenyl)(2-(piperidin-1-yl)ethoxy)methyl)-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid (compounds N51 and N52) and (R)- and (S)-N-(1-(3-isopropyl-1H-pyrazole-5-carbonyl)pyrrolidin-3-yl)cyclopropane-carboxamide (compounds N54 and N55)...
March 14, 2018: Journal of Medicinal Chemistry
Mohammad Akbari, Nasser Mahna, Katam Ramesh, Ali Bandehagh, Silvia Mazzuca
Pistachio, one of the important tree nuts, is cultivated in arid and semi-arid regions where salinity is the most common abiotic stress encountered by this tree. However, the mechanisms underlying salinity tolerance in this plant are not well understood. In the present study, five 1-year-old pistachio rootstocks (namely Akbari, Badami, Ghazvini, Kale-Ghouchi, and UCB-1) were treated with four saline water regimes (control, 8, 12, and 16 dS m-1 ) for 100 days. At high salinity level, all rootstocks showed decreased relative water content (RWC), total chlorophyll content (TCHC), and carotenoids in the leaf, while ascorbic acid (AsA) and total soluble proteins (TSP) were reduced in both leaf and root organs...
March 12, 2018: Protoplasma
Courtney A Polenick, Amanda N Leggett, Donovan T Maust, Helen C Kales
OBJECTIVE: Medical care tasks are commonly provided by spouses caring for persons living with dementia (PLWDs). These tasks reflect complex care demands that may interfere with sleep, yet their implications for caregivers' sleep outcomes are unknown. The authors evaluated the association between caregivers' medical/nursing tasks (keeping track of medications; managing tasks such as ostomy care, intravenous lines, or blood testing; giving shots/injections; and caring for skin wounds/sores) and care-related sleep disturbances...
February 1, 2018: American Journal of Geriatric Psychiatry
Robert D Kale, Muhammad F Sarwar, Andrew Sopchak
No abstract text is available yet for this article.
February 2, 2018: Journal of Cardiothoracic and Vascular Anesthesia
Ali Bayram, Mehmet Kalkan, Nuri Ünsal, Ahmet Kale, Bekir Küçük, Cemil Mutlu
OBJECTIVE: The aim of the present study was to investigate the influence of blindness on ocular vestibular evoked myogenic potentials (oVEMP) responses. METHODS: Thirty-one subjects with unilateral blindness (UB group) and 25 age and sex-matched healthy subjects (control group) were recruited for the present study. The oVEMP responses including latency, amplitude and amplitude asymmetry ratio (AR) were measured and compared between the blind side, the contralateral eye of the UB group and the control subjects...
March 3, 2018: American Journal of Otolaryngology
Esra Sinem Kemer Doğan, Fatma Yeşim Kırzıoğlu, Burak Doğan, Özlem Fentoğlu, Banu Kale, Süleyman Akif Çarsancaklı, Hikmet Orhan
BACKGROUND: Periodontal disease is shown to be aggravated by an increase in the count of metabolic risk factors. This study aims to evaluate the effects of metabolic risk factors on periodontal parameters and salivary oxidative stress markers related to menopausal status. METHODS: One hundred and seventy-six women were categorized according to menopausal status, either premenopause (Pre/M) (n = 86) or postmenopause (Post/M) (n = 90). The count of metabolic risk factors was evaluated...
March 2018: Journal of Periodontology
Katyelle Rafael, Ariella A Marchioro, Cristiane M Colli, Bruna T Tiyo, Fernanda F Evangelista, Renata C Bezagio, Ana L Falavigna-Guilherme
Background: In order to investigate the occurrence of Giardia duodenalis and its genotypes in vegetables that are consumed raw, we analyzed samples cultivated with organic or chemical fertilizer, sold in street markets and from community vegetable gardens in an urban area located in Southern Brazil. Methods: We analyzed 130 samples of vegetables such as crisp lettuce, regular lettuce, kale, chicory and rocket, from street markets, and 130 from community gardens...
March 6, 2018: Transactions of the Royal Society of Tropical Medicine and Hygiene
Mohd Nauman, R K Kale, Rana P Singh
BACKGROUND: Salix aegyptiaca is known for its medicinal properties mainly due to the presence of salicylate compounds. However, it also contains other beneficial phytochemicals such as gallic acid, quercetin, rutin and vanillin. The aim of the study was to examine the redox potential, antioxidant and anti-inflammatory activity of these phytochemicals along with acetylsalicylic acid. METHODS: The redox potential and antioxidant activity of gallic acid, quercetin, rutin, vanillin and acetylsalicylic acid were determined by oxidation-reduction potential electrode method and 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay, respectively...
March 7, 2018: BMC Complementary and Alternative Medicine
Eleuza R Machado, Iriani R Maldonade, Roberta F R Riquette, Vinícios S Mendes, Rodrigo Gurgel-Gonçalves, Veronica C Ginani
The consumption of raw vegetables is related to health benefits. However, these foods might be source of foodborne diseases. The objective of the present study was to perform a microbiological and parasitological evaluation of the leafy vegetables commercially sold in five regions of Brazil at public wholesale markets. The 12 types of leafy vegetables (144 samples) were curly lettuce, looseleaf lettuce, red lettuce, chives, coriander, kale, basil, arugula, parsley, iceberg lettuce, chicory, and bean sprouts...
April 2018: Journal of Food Protection
Ganesh V Sangle, Mohan Patil, Nitin J Deshmukh, Sushant A Shengule, Shantibhushan Kamble, Kiran Kumar Vuppalavanchu, Sushil Kale, Mirza Layeeq Ahmed Baig, Geetchandra Singh, Javed Shaikh, Jitendra Tripathi, P Aravindababu
PURPOSE: Sitagliptin, a dipeptidyl peptidase (DPP)-IV inhibitor approved for the treatment of type 2 diabetes, is reported to be more efficacious in Indian patients than non-Indian patient population. The objective of the study was to evaluate pharmacokinetic and pharmacodynamic (PK/PD) parameters of single-dose sitagliptin 100 mg (Januvia) in healthy Indian male participants. METHOD: In a randomised, single-dose, open-label, three-treatment, three-period, three-sequence, crossover bioavailability study, 18 healthy male participants received single-dose of sitagliptin under fasted and fed conditions...
March 6, 2018: European Journal of Clinical Pharmacology
Kamila Kasprzak, Tomasz Oniszczuk, Agnieszka Wójtowicz, Monika Waksmundzka-Hajnos, Marta Olech, Renata Nowak, Renata Polak, Anna Oniszczuk
Prohealth food contains specific components which have positive influence on the health and well-being of the consumer. An important position among bioactive compounds occurs for polyphenols. Many results have indicated that an increased intake of phenolic compounds may reduce the risk of cardiovascular diseases and type 2 diabetes. The objective of the study was production of extruded corn snacks with addition (0, 2, 4, 6, and 8%) of kale ( Brassica oleracea L. var. sabellica )-a polyphenol-rich plant. Afterwards, high-performance liquid chromatography-mass spectrometry (LC-ESI-MS/MS) and antioxidant activity analyses of snack extracts were performed...
2018: Journal of Analytical Methods in Chemistry
Sun Young Kim, Jai-Eok Park, Eun Ok Kim, Sue Ji Lim, Eui Jeong Nam, Ji Ho Yun, GyHye Yoo, Sang-Rok Oh, Hyoung Seok Kim, Chu Won Nho
A plant factory is a closed cultivation system that provides a consistent and modified environment for plant growth. We speculated that treatment of kale (Brassica oleracea) grown in a plant factory with NaCl, Na2 SeO3 , or both would increase the bioactive phytochemical levels including glucosinolates (GLSs) and isothiocyanates (ITCs), the key molecules in cancer prevention. The kale was harvested and analysed after treatment with NaCl and Na2 SeO3 alone or in combination for 1 or 2 weeks. Exposure to NaCl alone but not Na2 SeO3 increased plant root growth...
March 5, 2018: Scientific Reports
Sundar Tiwari, Nicholas Dickinson, David J Saville, Stephen D Wratten
The wheat bug, Nysius huttoni L. is an endemic New Zealand pest. The seedlings of forage brassicas are highly susceptible to direct feeding damage by this insect, and this can reduce plant establishment. Prophylactic use of pesticides is the usual practice for N. huttoni management. These practices have been linked to environmental pollution, biodiversity loss, and pollinator population declines in brassicas and other crops. Habitat management of the bug utilizing potential trap crops can be a better option for its management...
February 27, 2018: Journal of Economic Entomology
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