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https://www.readbyqxmd.com/read/28812344/in-vitro-bile-acid-binding-capacities-of-red-leaf-lettuce-and-cruciferous-vegetables
#1
Isabelle Yang, Guddadarangavvanahal Jayaprakasha, Bhimanagouda S Patil
In the present study, we tested the bile acid binding capacity of red leaf lettuce, red cabbage, red kale, green kale, and Brussels sprouts in vitro digestion process by simulating mouth, gastric, and intestinal digestion using six bile acids at physiological pH. Green and red kale exhibited significantly higher (86.5±2.9 and 89.7±0.9%) bile acid binding capacity compared with the other samples. Further, three different compositions of bile acids were tested to understand the effect on different health conditions...
August 16, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28800895/a-randomized-trial-of-a-web-based-platform-to-help-families-manage-dementia-related-behavioral-symptoms-the-wecareadvisor%C3%A2
#2
Laura N Gitlin, Helen J Kales, Katherine Marx, Barbara Stanislawski, Constantine Lyketsos
Dementia-related behavioral symptoms are challenging clinical features occurring across etiologies and disease progression. They are associated with increased healthcare utilization, nursing home placement, family upset and burden. Families typically manage behavioral symptoms without requisite knowledge, skills and guidance. We designed WeCareAdvisor™ as an easy-to-use, evidence-informed web-based platform. It provides families knowledge about dementia, daily tips, and a systematic approach to describe behaviors, investigate modifiable contributors, create treatment plans (WeCareAdvisor™ Prescription) consisting of management tips tailored to symptom presentation, and evaluate effectiveness...
August 8, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28799941/fluidized-glass-beads-reduce-fouling-in-a-novel-anaerobic-membrane-bioreactor
#3
B Düppenbecker, S Kale, M Engelhart, P Cornel
This study focuses on the use of fluidized glass beads as turbulence promoters in a laboratory-scale anaerobic membrane bioreactor treating municipal wastewater at 20 °C. The addition of fluidized glass beads into an external tubular ceramic membrane enabled the operation at low crossflow velocities of 0.053-0.073 m/s (mean fluxes between 5.5 and 9.7 L/(m(2)·h)) with runtimes >300 h. Glass beads with a diameter of 1.5 mm were more effective than smaller ones with a diameter of 0.8-1.2 mm. Increasing the bed voidage from 74 to 80% did not show any beneficial effect...
August 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28792988/-validity-of-information-on-birth-weight-for-studies-based-on-fetal-programming
#4
Gisele Almeida de Noronha, Pauline Lorena Kale, Tania Zdenka Guillén de Torres, Antonio Jose Leal Costa, Maria de Lourdes Tavares Cavalcanti, Moyses Szklo
Birth weight is essential information in fetal programming studies and is generally obtained retrospectively. In Brazil's Information System on Live Births (SINASC), birth weight is valid information but is not always accessible. The study aimed to establish an algorithm for the selection of the most reliable data source for birth weight in the absence of information in the SINASC database. In a cross-sectional study of 6-14-year-old schoolchildren in Niterói, Rio de Janeiro State, Brazil, in 2010, birth weight was collected through a self-completed questionnaire, interview, medical records from the Family Physician Program, and the SINASC database...
August 7, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28790167/chemoprotective-effects-of-butanol-fraction-of-buchholzia-coriacea-capparidaceae-against-type-2-diabetes-and-oxidative-stress-in-male-wistar-rats
#5
Amanda Chikaosolu Okolie, Oluwafemi Ezekiel Kale, Odutola Osilesi
Recent studies have shown that Type 2 diabetes (T2D) in rats can result through a synergy that link obesity to insulin resistance and β-cell dysfunction. This present study achieved T2D via high fructose (20%(w/v), p.o.), streptozotocin single dose (40 mg/kg, i.p.) (HFSTZ) in rats. Also, chemoprotective potential of butanol fraction of buchholzia coriacea (BFBC) was demonstrated. Control normal and diabetic untreated (HFSTZ-induced T2D) rats received carboxymethyl cellulose (1 mg/kg, p.o.). Diabetic rats received intragastric BFBC (20, 200, 400 mg/kg), glibenclamide (0...
August 8, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/28789779/management-of-blunt-cerebrovascular-injury-bcvi-in-the-multisystem-injury-patient-with-contraindications-to-immediate-anti-thrombotic-therapy
#6
Michelle K McNutt, A Cozette Kale, Ryan S Kitagawa, Ali H Turkmani, David W Fields, Sarah Baraniuk, Brijesh S Gill, Bryan A Cotton, Laura J Moore, Charles E Wade, Arthur Day, John B Holcomb
INTRODUCTION: Practice management guidelines for screening and treatment of patients with blunt cerebrovascular injury (BCVI) have been associated with a decreased risk of ischemic stroke. TREATMENT: of patients with BCVI and multisystem injuries that delays immediate antithrombotic therapy remains controversial. The purpose of this study was to determine the timing of BCVI treatment initiation, the incidence of stroke, and bleeding complications as a result of antithrombotic therapy in patients with isolated BCVI in comparison to those with BCVI complicated by multisystem injuries...
July 31, 2017: Injury
https://www.readbyqxmd.com/read/28764140/computed-tomographic-estimation-of-relationship-between-renal-volume-and-body-weight-of-an-individual
#7
Shweta Sudhakar Talhar, Jwalant E Waghmare, Lipika Paul, Sushilkumar Kale, Moreshwar R Shende
INTRODUCTION: Knowledge of normal range of size and volume of abdominal organs plays a vital role in clinical practices as various medical conditions affects the abdominal organs causing alteration in their dimensions. AIM: The present retrospective study was done to establish the normal range of renal volume in study population and to see the correlation between renal volume and body weight of an individual. MATERIALS AND METHODS: Computed tomographic evaluations of kidneys were performed on 140 kidneys of 70 individuals who had undergone abdominal CT scan for indications other than renal disease...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28762355/bismuth-subnitrate-iodoform-parafin-paste-used-in-the-management-of-inflammatory-follicular-cyst-report-of-two-cases
#8
Abdul Morawala, Dayanand Shirol, Yusuf Chunawala, Nupur Kanchan, Mayuri Kale
Dentigerous cyst or follicular cyst is a type of odontogenic cyst which encloses the crown of an unerupted tooth and is attached to the amelocemental junction and is the second most common odontogenic cyst contributing about 16.6% to 21.3% of all odontogenic cysts. Occurrence of Dentigerous cysts according to Shear is usually in 3rd and 4th decade in contrast to this finding Shibata et al showed that the age of discovery of the dentigerous cyst was generally 9-11 years. The treatment indicated for dentigerous cysts are surgical enucleation of the cyst, along with removal of the involved tooth; or the use of a marsupialization technique, which removes the cyst while preserving the developing tooth...
July 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28756482/epr-oximetry-of-cetuximab-treated-head-and-neck-tumours-in-a-mouse-model
#9
H Gustafsson, A Kale, A Dasu, A Lund, P-H Edqvist, K Roberg
Head and neck squamous cell carcinoma (HNSCC) tumours are associated with high mortality despite advances in therapy. The monoclonal antibody cetuximab (Erbitux(®)) has been approved for the treatment of advanced HNSCC. However, only a subset of HNSC patients receiving cetuximab actually responds to treatment, underlining the need for a means to tailor treatments of individual patients. The aim of the present study was to investigate the effect of cetuximab treatment on tumour growth, on tumour partial oxygen pressure as measured by LiPc electron paramagnetic resonance oximetry and on the expression of proteins involved in tumour growth, metabolism and hypoxia...
July 29, 2017: Cell Biochemistry and Biophysics
https://www.readbyqxmd.com/read/28755031/interspecies-differences-in-plasma-concentrations-of-25-hydroxyvitamin-d3-and-dermal-vitamin-d-synthesis-of-kiwi-apteryx-mantelli-tuatara-sphenodon-punctatus-and-new-zealand-sea-lions-phocarctos-hookeri
#10
Madhumita S Kale, Keren E Dittmer, Wendi D Roe, Brett D Gartrell
Vitamin D plays a central role in calcium homeostasis of most vertebrates, and is obtained in different species through diet, dermal synthesis, or a combination of both. The aim of this study was to determine the predominant routes of Vitamin D synthesis in three disparate species, brown kiwi (Apteryx mantelli), tuatara (Sphenodon punctatus), and New Zealand sea lions (Phocarctos hookeri). We surveyed plasma concentrations of 25-hydroxyvitamin D2 and D3, analysed environmental conditions and life history factors, and determined the ability of skin samples to synthesise Vitamin D3 on exposure to ultraviolet-B radiation...
July 28, 2017: Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology
https://www.readbyqxmd.com/read/28754817/multifaceted-role-of-btla-in-the-control-of-cd8-t-cell-fate-after-antigen-encounter
#11
Krit Ritthipichai, Cara Haymaker, Melisa Martinez-Paniagua, Andrew Aschenbrenner, Xiaohui Yi, Minying Zhang, Charuta Kale, Yared Hailemichael, Willem W Overwijk, Luis Vence, Jason Roszik, Navin Varadarajan, Roza Nurieva, Laszlo G Radvanyi, Patrick Hwu, Chantale Bernatchez
Adoptive T-cell therapy using autologous tumor-infiltrating lymphocytes (TIL) has shown an overall clinical response rate 40-50% in metastatic melanoma patients. BTLA (B-and-T lymphocyte attenuator) expression on transferred CD8(+) TIL was associated with better clinical outcome. The suppressive function of the ITIM and ITSM motifs of BTLA is well described. Here, we sought to determine the functional characteristics of the CD8(+)BTLA(+)TIL subset and define the contribution of the Grb2 motif of BTLA in T cell co-stimulation...
July 28, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28754586/distress-associated-with-dementia-related-psychosis-and-agitation-in-relation-to-healthcare-utilization-and-costs
#12
Donovan T Maust, Helen C Kales, Ryan J McCammon, Frederic C Blow, Amanda Leggett, Kenneth M Langa
OBJECTIVES: Explore the relationship between behavioral and psychological symptoms of dementia (BPSD; specifically, delusions, hallucinations, and agitation/aggression) and associated caregiver distress with emergency department (ED) utilization, inpatient hospitalization, and expenditures for direct medical care. DESIGN/SETTING/PARTICIPANTS: Retrospective cross-sectional cohort of participants with dementia (N = 332) and informants from the Aging, Demographics, and Memory Study, a nationally representative survey of U...
May 25, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28753935/influences-of-orally-taken-carotenoid-rich-curly-kale-extract-on-collagen-i-elastin-index-of-the-skin
#13
Martina C Meinke, Ceylan K Nowbary, Sabine Schanzer, Henning Vollert, Jürgen Lademann, Maxim E Darvin
Two differently designed, spatially resolved reflectance spectroscopy-based scanners and two-photon tomography were used for noninvasive in vivo determination of cutaneous carotenoids, and collagen I/elastin aging index of dermis, respectively, in the skin of 29 healthy female volunteers between 40 and 56 years of age. The volunteers received a supplement in the form of a carotenoid-rich natural curly kale extract containing 1650 µg of carotenoids in total (three capsules of 550 µg), once a day. Measurements were taken before, after 5 months and after 10 months of daily supplementation...
July 19, 2017: Nutrients
https://www.readbyqxmd.com/read/28749430/evaluation-of-the-nutritional-quality-of-chinese-kale-brassica-alboglabra-bailey-using-uhplc-quadrupole-orbitrap-ms-ms-based-metabolomics
#14
Ya-Qin Wang, Li-Ping Hu, Guang-Min Liu, De-Shuang Zhang, Hong-Ju He
Chinese kale (Brassica alboglabra Bailey) is a widely consumed vegetable which is rich in antioxidants and anticarcinogenic compounds. Herein, we used an untargeted ultra-high-performance liquid chromatography (UHPLC)-Quadrupole-Orbitrap MS/MS-based metabolomics strategy to study the nutrient profiles of Chinese kale. Seven Chinese kale cultivars and three different edible parts were evaluated, and amino acids, sugars, organic acids, glucosinolates and phenolic compounds were analysed simultaneously. We found that two cultivars, a purple-stem cultivar W1 and a yellow-flower cultivar Y1, had more health-promoting compounds than others...
July 27, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28749397/action-oriented-colour-coded-foot-length-calliper-for-primary-healthcare-workers-as-a-proxy-for-birth-weight-gestational-period
#15
Asha K Pratinidhi, Abhijit C Bagade, Satish V Kakade, Hemangi P Kale, Vinayak Y Kshirsagar, Rohini Babar, Shilpa Bagal
BACKGROUND & OBJECTIVES: Foot length of the newborn has a good correlation with the birth weight and is recommended to be used as a proxy measure. There can be variations in the measurement of foot length. A study was, therefore, carried out to develop a foot length calliper for accurate foot length measurement and to find cut-off values for birth weight and gestational age groups to be used by primary healthcare workers. METHODS: This study was undertaken on 645 apparently healthy newborn infants with known gestational age...
March 2017: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28735855/dementia-prevention-intervention-and-care
#16
REVIEW
Gill Livingston, Andrew Sommerlad, Vasiliki Orgeta, Sergi G Costafreda, Jonathan Huntley, David Ames, Clive Ballard, Sube Banerjee, Alistair Burns, Jiska Cohen-Mansfield, Claudia Cooper, Nick Fox, Laura N Gitlin, Robert Howard, Helen C Kales, Eric B Larson, Karen Ritchie, Kenneth Rockwood, Elizabeth L Sampson, Quincy Samus, Lon S Schneider, Geir Selbæk, Linda Teri, Naaheed Mukadam
No abstract text is available yet for this article.
July 19, 2017: Lancet
https://www.readbyqxmd.com/read/28730528/sulforaphane-promotes-mitochondrial-protection-in-sh-sy5y-cells-exposed-to-hydrogen-peroxide-by-an-nrf2-dependent-mechanism
#17
Marcos Roberto de Oliveira, Flávia de Bittencourt Brasil, Cristina Ribas Fürstenau
Sulforaphane (SFN; C6H11NOS2) is an isothiocyanate found in cruciferous vegetables, such as broccoli, kale, and radish. SFN exhibits antioxidant, anti-apoptotic, anti-tumor, and anti-inflammatory activities in different cell types. However, it was not previously demonstrated whether and how this natural compound would exert mitochondrial protection experimentally. Therefore, we investigated here the effects of a pretreatment (for 30 min) with SFN at 5 μM on mitochondria obtained from human neuroblastoma SH-SY5Y cells exposed to hydrogen peroxide (H2O2) at 300 μM for 24 h...
July 20, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28730203/growth-study-of-hierarchical-ag3po4-laco3oh-heterostructures-and-their-efficient-photocatalytic-activity-for-rhb-degradation
#18
Virendrakumar G Deonikar, Santosh S Patil, Mohaseen S Tamboli, Jalindar D Ambekar, Milind V Kulkarni, Rajendra P Panmand, Govind G Umarji, Manish D Shinde, Sunit B Rane, Nagegownivari R Munirathnam, Deepak R Patil, Bharat B Kale
We have demonstrated the synthesis of Ag3PO4/LaCO3OH (APO/LCO) heterostructured photocatalysts by an in situ wet chemical method. From pre-screening evaluations of photocatalysts with APO/(x wt% LCO) composites with mass ratios of x = 5, 10, 15, 20, 25 and 30 wt%, we found that the APO/LCO (20 wt%) exhibited a superior photocatalytic activity for organic pollutant remediation. Therefore, an optimised photocatalyst APO/LCO (20 wt%) is selected for the present study and we investigate the effect of a mixed solvent system (H2O:THF) on the morphology, which has a direct effect on the photocatalytic performance...
August 9, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28727377/laparoscopic-pectopexy-initial-experience-of-single-center-with-a-new-technique-for-apical-prolapse-surgery
#19
Ahmet Kale, Alper Biler, Hasan Terzi, Taner Usta, Ebru Kale
OBJECTIVE: To share our first experience with laparoscopic pectopexy, a new technique for apical prolapse surgery, and to evaluate the feasibility of this technique. MATERIALS AND METHODS: Seven patients with apical prolapse underwent surgery with laparoscopic pectopexy. The lateral parts of the iliopectineal ligament were used for a bilateral mesh fixation of the descended structures. The medical records of the patients were reviewed, and the short-term clinical outcomes were analyzed...
June 14, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28716471/clinical-significance-of-preoperative-serum-c-reactive-protein-in-oral-squamous-cell-carcinoma
#20
S Acharya, J Kale, K Hallikeri, V Anehosur, D Arnold
C-reactive protein (CRP) is an index of systemic inflammation. However, CRP is not usually assessed preoperatively. Hence the study intended to evaluate the preoperative serum CRP levels in oral squamous cell carcinoma (OSCC) patients and to analyse its relationship with the clinicopathologic characteristics. CRP values for 60 OSCCs and 30 healthy controls were evaluated using a CRP assessment kit and spectrophotometer. The Mann-Whitney U test, χ(2) test, receiver operating characteristic (ROC) curve analysis, and logistic regression were applied...
July 14, 2017: International Journal of Oral and Maxillofacial Surgery
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