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https://www.readbyqxmd.com/read/28811709/bone-marrow-derived-monocyte-infusion-improves-hepatic-fibrosis-by-decreasing-osteopontin-tgf-%C3%AE-1-il-13-and-oxidative-stress
#1
Veruska Cintia Alexandrino de Souza, Thiago Almeida Pereira, Valéria Wanderley Teixeira, Helotonio Carvalho, Maria Carolina Accioly Brelaz de Castro, Carolline Guimarães D'assunção, Andréia Ferreira de Barros, Camila Lima Carvalho, Virgínia Maria Barros de Lorena, Vláudia Maria Assis Costa, Álvaro Aguiar Coelho Teixeira, Regina Celia Bressan Queiroz Figueiredo, Sheilla Andrade de Oliveira
AIM: To evaluate the therapeutic effects of bone marrow-derived CD11b(+)CD14(+) monocytes in a murine model of chronic liver damage. METHODS: Chronic liver damage was induced in C57BL/6 mice by administration of carbon tetrachloride and ethanol for 6 mo. Bone marrow-derived monocytes isolated by immunomagnetic separation were used for therapy. The cell transplantation effects were evaluated by morphometry, biochemical assessment, immunohistochemistry and enzyme-linked immunosorbent assay...
July 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28810860/tartrate-resistant-acid-phosphate-as-biomarker-of-bone-turnover-over-the-lifespan-and-different-physiologic-stages-in-sheep
#2
José A Camassa, Camila C Diogo, João P A Bordelo, Marília de A Bonelli, Carlos A Viegas, Jorge T Azevedo, Nuno Dourado, Isabel R Dias
BACKGROUND: Currently, the best resources for assessment of bone tissue using imaging techniques are expensive and available in few medical facilities, thus serum or urinary bone turnover biomarkers could be useful as early indicators of prognosis. However, there is a wide range of variability in bone turnover markers due to several factors, such as different ages and metabolic stages, thus it is important to have as much data published on the subject as possible. The aim of this study was therefore to generate a reference range for alkaline phosphatase (ALP) and tartrate-resistant acid phosphatase (TRAP) and validate the already published data...
August 15, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28809924/species-delimitation-in-frogs-from-south-american-temperate-forests-the-case-of-eupsophus-a-taxonomically-complex-genus-with-high-phenotypic-variation
#3
Claudio Correa, Dayana Vásquez, Camila Castro-Carrasco, Álvaro Zúñiga-Reinoso, Juan Carlos Ortiz, R Eduardo Palma
One of the most characteristic and abundant amphibian taxa of South American temperate forests is Eupsophus. The ten currently recognized species of the genus have been divided in two species groups, roseus and vertebralis, but most of them, eight, belong to the roseus group. Recent phylogeographic and phylogenetic studies have suggested that species diversity of the roseus group could be underestimated. An examination of the literature shows that species of the roseus group exhibit high levels of variation in their external characteristics, particularly those used as diagnostic characters, which compromises their taxonomy and hinders their field recognition...
2017: PloS One
https://www.readbyqxmd.com/read/28808475/yacon-smallanthus-sonchifolius-leaf-extract-attenuates-hyperglycemia-and-skeletal-muscle-oxidative-stress-and-inflammation-in-diabetic-rats
#4
Klinsmann Carolo Dos Santos, Bianca Guerra Bueno, Luana Ferreira Pereira, Fabiane Valentini Francisqueti, Mariana Gobbo Braz, Lahis Fernandes Bincoleto, Lilian Xavier da Silva, Ana Lúcia A Ferreira, Ana Cláudia de Melo Stevanato Nakamune, C-Y Oliver Chen, Jeffrey B Blumberg, Camila Renata Corrêa
The effects of hydroethanolic extract of Yacon leaves (HEYL) on antioxidant, glycemic, and inflammatory biomarkers were tested in diabetic rats. Outcome parameters included glucose, insulin, interleukin-6 (IL-6), and hydrophilic antioxidant capacity (HAC) in serum and IL-6, HAC, malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) in soleus. The rats (10/group) were divided as follows: C, controls; C + Y, HEYL treated; DM, diabetic controls; and DM + Y, diabetic rats treated with HEYL...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28806995/robot-supported-assessment-of-balance-in-standing-and-walking
#5
REVIEW
Camila Shirota, Edwin van Asseldonk, Zlatko Matjačić, Heike Vallery, Pierre Barralon, Serena Maggioni, Jaap H Buurke, Jan F Veneman
Clinically useful and efficient assessment of balance during standing and walking is especially challenging in patients with neurological disorders. However, rehabilitation robots could facilitate assessment procedures and improve their clinical value. We present a short overview of balance assessment in clinical practice and in posturography. Based on this overview, we evaluate the potential use of robotic tools for such assessment. The novelty and assumed main benefits of using robots for assessment are their ability to assess 'severely affected' patients by providing assistance-as-needed, as well as to provide consistent perturbations during standing and walking while measuring the patient's reactions...
August 14, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28805508/corrigendum-to-effectiveness-of-a-multidimensional-web-based-intervention-program-to-change-brazilian-health-practitioners-attitudes-toward-the-lesbian-gay-bisexual-and-transgender-population
#6
Angelo Brandelli Costa, Paola Fagundes Pase, Eric Seger de Camargo, Camila Guaranha, Adriano Henrique Caetano, Daniel Kveller, Heitor Thomé da Rosa Filho, Ramiro Figueiredo Catelan, Silvia Helena Koller, Henrique Caetano Nardi
Corrigendum to: J Health Psychol DOI 10.1177/1359105316628748 Unfortunately, the online published article has an error in one of the analyses. On page 365, fifth paragraph, the corrected statistical report is (Δ 1.66, 95% CI [3.32, .01], t (305) = -1.98, p<.05), not (Δ 1.66, 95% CI [3.32, .01], t (305) = -1.66, p <.05). In spite of this correction, there is no change in the direction of the test and therefore in the interpretation of this result.
June 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28803852/dynamic-feet-distance-a-new-functional-assessment-during-treadmill-locomotion-in-normal-and-thoracic-spinal-cord-injured-rats
#7
Camila Cardoso Diogo, Luís Maltez da Costa, José Eduardo Pereira, Vítor Filipe, Pedro Alexandre Couto, Luís G Magalhães, Stefano Geuna, Paulo A Armada-da-Silva, Ana Colette Maurício, Artur Severo Varejão
Of all the detrimental effects of spinal cord injury (SCI), one of the most devastating is the disruption of the ability to perform functional movement. Very little is known on the recovery of hindlimb joint kinematics after clinically-relevant contusive thoracic lesion in experimental animal models. A new functional assessment instrument, the dynamic feet distance (DFD) was used to describe the distance between the two feet throughout the gait cycle in normal and affected rodents. The purpose of this investigation was the evaluation and characterization of the DFD during treadmill locomotion in normal and T9 contusion injured rats, using three-dimensional (3D) instrumented gait analysis...
August 10, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28803725/schistosomiasis-drugs-used-and-treatment-strategies
#8
REVIEW
Lidiany da Paixão Siqueira, Danilo Augusto Ferreira Fontesa, Cindy Siqueira Britto Aguilera, Taysa Renata Ribeiro Timoteo, Matheus Alves Angelos, Laysa Creusa Paes Barreto Barros Silva, Camila Gomes de Melo, Larissa Araújo Rolim, Rosali Maria Ferreira da Silva, Pedro José Rolim Neto
Neglected tropical diseases (NTDs) affect millions of people in different geographic regions, especially the poorest and most vulnerable. Currently NTDs are prevalent in 149 countries, seventeen of these neglected tropical parasitic diseases are classified as endemic. One of the most important of these diseases is schistosomiasis, also known as bilharzia, a disease caused by the genus Schistosoma. It presents several species, such as S. haematobium, S. japonicum and S. mansoni, the latter being responsible for parasitosis in Brazil...
August 10, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28802897/the-different-effects-of-lithium-and-tamoxifen-on-memory-formation-and-the-levels-of-neurotrophic-factors-in-the-brain-of-male-and-female-rats
#9
Samira S Valvassori, Cenita Borges, Roger B Varela, Daniela V Bavaresco, Guilherme Bianchini, Edemilson Mariot, Camila O Arent, Wilson R Resende, Josiane Budni, João Quevedo
Lithium (Li) is a mood-stabilizing drug used in the treatment of bipolar disorder (BD). Recently, preclinical studies have demonstrated the potential of tamoxifen (TMX) in the treatment of acute episodes of BD. However, the prolonged use of TMX for mood disorders treatment is controversial. In this study, we evaluated the effects of TMX or Li on cognitive behavior, as well as the levels of neurotrophic factors in the brain of male and female rats. Male and female Wistar rats received administrations of water (control group), TMX or Li via gavage for a period of 28 days; the rats were then subjected to the open-field test (to evaluate spontaneous locomotion), and the novel object recognition and step-down inhibitory avoidance tests (to evaluate cognition)...
August 9, 2017: Brain Research Bulletin
https://www.readbyqxmd.com/read/28802812/noninvasive-brain-stimulation-improves-hemispatial-neglect-after-stroke-a-systematic-review-and-meta-analysis
#10
REVIEW
Ana Paula S Salazar, Patrícia G Vaz, Ritchele R Marchese, Cinara Stein, Camila Pinto, Aline S Pagnussat
OBJECTIVE: To evaluate the effectiveness of noninvasive brain stimulation (NIBS) - repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) - on hemispatial neglect and performance in activities of daily living (ADL) after stroke. DATA SOURCES: MEDLINE (Pubmed), Embase, Cochrane CENTRAL, SCOPUS, Scielo and Physiotherapy Evidence Database (PEDro) were searched from database inception to December 2016. DATA SELECTION: Randomized controlled trials or crossover trials focused on determining the effects of tDCS or rTMS combined or not combined with other therapies for hemispatial neglect after stroke...
August 9, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28802387/sleep-quality-and-communication-aspects-in-children
#11
Camila de Castro Corrêa, Maria Renata José, Eduardo Carvalho Andrade, Mariza Ribeiro Feniman, Ana Paula Fukushiro, Giédre Berretin-Felix, Luciana Paula Maximino
OBJECTIVES: To correlate quality of life of children in terms of sleep, with their oral language skills, auditory processing and orofacial myofunctional aspects. METHODS: Nineteen children (12 males and seven females, in the mean age 9.26) undergoing otorhinolaryngological and speech evaluations participated in this study. The OSA-18 questionnaire was applied, followed by verbal and nonverbal sequential memory tests, dichotic digit test, nonverbal dichotic test and Sustained Auditory Attention Ability Test, related to auditory processing...
September 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28801774/bcl-2-antigen-expression-in-luminal-a-and-triple-negative-breast-cancer
#12
Carla Solange Escórcio-Dourado, Luana Mota Martins, Camila Maria Simplício-Revoredo, Fabiane Araújo Sampaio, Cléciton Braga Tavares, João Paulo da Silva-Sampaio, Umbelina Soares Borges, Francisco Adelton Alves-Ribeiro, Pedro Vitor Lopes-Costa, José Charles Lima-Dourado, Benedito Borges da Silva
Biomarkers for the prognosis of breast cancer have been routinely used in clinical practice, including the expression of hormone receptors, Ki-67 and HER-2. More recently, Bcl-2 has been recognized as an important prognostic factor in breast cancer, although controversies persist with respect to the significance of its expression. The aim of the present study was to evaluate Bcl-2 antigen expression in luminal A and triple-negative breast cancer. Sixty women with invasive ductal carcinoma were included in the study and divided into two groups: Group A (luminal A) and Group B (triple-negative), with 30 cases in each group...
August 11, 2017: Medical Oncology
https://www.readbyqxmd.com/read/28801728/arctium-minus-crude-extract-presents-antinociceptive-effect-in-a-mice-acute-gout-attack-model
#13
Susana Paula Moreira Fischer, Indiara Brusco, Camila Camponogara, Mariana Piana, Henrique Faccin, Luciana Assis Gobo, Leandro Machado de Carvalho, Sara Marchesan Oliveira
Gout is a disorder that triggers a severe inflammatory reaction which generates episodes of intense pain and discomfort to the patient. Arctium minus (Hill) Bernh. (Asteraceae) is known as "burdock" and displays anti-inflammatory, antinociceptive, against rheumatic pain and radical-scavenging activities. Species of the genus Arctium have been used in assistant therapy of gout and other inflammatory processes. We investigated the antinociceptive and anti-edematogenic effects of the crude extract of A. minus seeds in an acute gout attack model induced by intra-articular injection of monosodium urate (MSU) crystals in adult male Swiss mice (25-30 g)...
August 11, 2017: Inflammopharmacology
https://www.readbyqxmd.com/read/28798145/tnf-induces-neutrophil-adhesion-via-formin-dependent-cytoskeletal-reorganization-and-activation-of-%C3%AE-integrin-function
#14
Angélica Aparecida Antoniellis Silveira, Venina Marcela Dominical, Camila Bononi Almeida, Hanan Chweih, Wilson Alves Ferreira, Cristina Pontes Vicente, Fabio Trindade Maranhão Costa, Claudio C Werneck, Fernando Ferreira Costa, Nicola Conran
Although essential for inflammatory responses, leukocyte recruitment to blood vessel walls in response to inflammatory stimuli, such as TNF-α, can contribute to vascular occlusion in inflammatory diseases, including atherosclerosis. We aimed to further characterize the mechanisms by which TNF stimulates adhesive and morphologic alterations in neutrophils. Microfluidic and intravital assays confirmed the potent effect that TNF has on human and murine neutrophil adhesion and recruitment in vitro and in vivo, respectively...
August 10, 2017: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/28797621/influence-of-acute-myeloid-leukemia-progression-on-the-prognosis-of-831-patients-with-myelodysplastic-syndromes-from-the-argentine-database
#15
Alicia Enrico, Yesica Bestach, Maria Gabriela Flores, Jorge Arbelbide, Camila Serale, Viviana Novoa, Renée Crisp, María Marta Rivas, Irene Larripa, Carolina Belli
BACKGROUND: A large group of patients with myelodysplastic syndromes (MDS) will die of causes intrinsic to bone marrow failure. One third of patients will develop acute myeloid leukemia (AML), which is associated with an extremely poor outcome and a short survival. Our objectives were to analyze the prognostic variables and scoring systems in the attempt to determine the influence of progression on the overall survival of MDS patients. PATIENTS AND METHODS: We performed a retrospective analysis of 831 MDS patients, including those from the Argentine Registry...
June 23, 2017: Clinical Lymphoma, Myeloma & Leukemia
https://www.readbyqxmd.com/read/28795959/zika-virus-and-the-eye
#16
Bruno de Paula Freitas, Camila V Ventura, Mauricio Maia, Rubens Belfort
PURPOSE OF REVIEW: The aim of this study was to review the ocular findings related to the Zika virus (ZIKV) based on the main studies published to date, describe the patterns of the lesions and risk factors, and identify the public health implications and scientific importance of this emerging disease. RECENT FINDINGS: In most studies, the ZIKV seems related to congenital ocular lesions and most mothers reported mild symptoms during the first pregnancy trimester...
August 8, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28794984/seasonality-richness-and-prevalence-of-intestinal-parasites-of-three-neotropical-primates-alouatta-seniculus-ateles-hybridus-and-cebus-versicolor-in-a-fragmented-forest-in-colombia
#17
Silvia Rondón, Mario Ortiz, Cielo León, Nelson Galvis, Andrés Link, Camila González
Studies on parasites infecting non-human primates are essential to better understand the potential threat to humans of zoonoses transmission, particularly under the current processes of pervasive land use change and biodiversity loss. The natural ecosystems in the Middle Magdalena river basin in Colombia have suffered a dramatic reduction and transformation into pastures and agroindustrial monocultures, threatening their biodiversity, and probably affecting the dynamics between parasites and their hosts, as well as altering the disease transmission cycles between wild populations and humans...
December 2017: International Journal for Parasitology. Parasites and Wildlife
https://www.readbyqxmd.com/read/28793370/prevalence-of-tdp-43-proteinopathy-in-cognitively-normal-older-adults-systematic-review-and-meta-analysis
#18
Camila Nascimento, Ana Tereza Di Lorenzo Alho, Caroline Bazan Conceição Amaral, Renata Elane Paraizo Leite, Ricardo Nitrini, Wilson Jacob-Filho, Carlos Augusto Pasqualucci, Suvi Rosa Kastehelmi Hokkanen, Sally Hunter, Hannah Keage, Gabor G Kovacs, Lea Tenenholz Grinberg, Claudia Kimie Suemoto
OBJECTIVE: To perform a systematic review and meta-analysis on the prevalence of TDP-43 proteinopathy in cognitively normal older adults. METHODS: We systematically reviewed and performed a meta-analysis on the prevalence of TDP-43 proteinopathy in older adults with normal cognition, evaluated by the Mini-Mental State Examination or the Clinical Dementia Rating. We estimated the overall prevalence of TDP-43 using random-effect models, and stratified by age, sex, sample size, study quality, antibody used to assess TDP-43 aggregates, analyzed brain regions, Braak stage, CERAD score, hippocampal sclerosis, and geographic location...
August 9, 2017: Neuropathology and Applied Neurobiology
https://www.readbyqxmd.com/read/28793008/geo-environmental-zoning-using-physiographic-compartmentalization-a-proposal-for-supporting-sustainable-decision-making
#19
Claudia V S Corrêa, Fábio A G V Reis, Lucilia C Giordano, Adriano Bressane, Camila J Chaves, Ana Maria C DO Amaral, Hermes D Brito, Gerson A DE Medeiros
The geo-environmental zoning represents an important strategy in the territorial management. However, it requires a logical and structured procedure. Therefore, an approach using physiographic compartmentalization is proposed and applied as case study in a region covered by the topographic maps of São José dos Campos and Jacareí, Brazil. This region has great geological and geomorphological peculiarities, beyond being a place with large human interventions because of its quickly economic growth. The methodology is based on photointerpretation techniques and remote sensing in GIS environment...
August 7, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28792372/treatment-failure-of-bacterial-vaginosis-is-not-associated-with-higher-loads-of-atopobium-vaginae-and-gardnerella-vaginalis
#20
Carolina Sanitá Tafner Ferreira, Gilbert Gerard Donders, Cristina Maria Garcia de Lima Parada, Andrea da Rocha Tristão, Thaiz Fernandes, Márcia Guimarães da Silva, Camila Marconi
PURPOSE: Cervicovaginal Atopobium vaginae and Gardnerella vaginalis are strongly associated with bacterial vaginosis (BV) and are the main components of vaginal biofilms. The low efficacy of BV treatment with metronidazole may be due to the presence of such biofilms. Thus, the aim of this study was to compare the pretreatment cervicovaginal loads of A. vaginae and G. vaginalis for women who restored normal flora and those who persisted with BV after a full course of oral metronidazole...
August 10, 2017: Journal of Medical Microbiology
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