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Hemangioendothelioma

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https://www.readbyqxmd.com/read/29142751/hepatic-epithelioid-hemangioendothelioma-with-metastasis-to-the-mesentery-of-the-small-intestine-a-case-report
#1
Daichi Nakamura, Yasushi Adachi, Yasuaki Nakashima, Noriko Sakaida, Hiroyuki Narahara, Ming Shi, Michihiko Tsubono, Susumu Ikehara
Epithelioid hemangioendothelioma (EHAE) is a vascular tumor which, due to its rarity, is often misdiagnosed as other hepatic tumors based on radiological characteristics. We herein report a case of EHAE in the liver and the mesentery of the small intestine. A 64-year-old asymptomatic woman was admitted to the hospital due to a hepatic tumor identified using computed tomography (CT). An enhanced CT scan revealed multiple tumors in the liver and a tumor in the mesentery. One of the hepatic tumors and the mesenteric tumor were resected and histologically examined...
November 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29137048/apatinib-for-the-treatment-of-pulmonary-epithelioid-hemangioendothelioma-a-case-report-and-literature-review
#2
Zhipeng Zheng, Hanying Wang, Hanliang Jiang, Enguo Chen, Jun Zhang, Xinyou Xie
RATIONALE: Pulmonary epithelioid hemangioendothelioma (P-EHE) is a rare tumor, with no established standard treatment. Overexpression of vascular endothelial growth factor receptor 2 (VEGFR-2) has been reported in some P-EHE patients. Apatinib, a new small molecule tyrosine kinase inhibitor that specifically targets VEGFR-2, has therapeutic benefits in some advanced tumors. However, its efficacy in P-EHE cases has not been reported. PATIENT CONCERNS: Herein, we presented a 44-year-old man with recurrent hemoptysis for approximately 9 years...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29136695/-metastatic-epithelioid-hemangioendothelioma-of-peritoneum-with-florid-mesothelial-hyperplasia-mimicking-malignant-mesothelioma-report-of-a-case
#3
M Zhao, L L Yu, Q L Tang, X L He
No abstract text is available yet for this article.
November 8, 2017: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/29136688/-characteristics-of-erg-fli-1-cd34-cd31-and-f%C3%A2-rag-expression-in-hepatic-malignant-vascular-tumors
#4
Z B Wang, X J An, J F Deng, J H Liu, H Y Shi
Objective: To investigate the expression of ERG, Fli-1, CD34, CD31 and factor Ⅷ-related antigen(FⅧRAg) in hepatic malignant vascular tumors. Methods: A retrospective analysis was conducted on 63 cases of primary hepatic malignant vascular tumors and 31 cases of hepatic other malignant spindle cell tumors collected during January 1986 to January 2014. EnVision method was used to detect the expression of ERG, Fli-1, CD34, CD31, FⅧRAg. Results: Sixty-three cases of malignant vascular tumors, including 24 cases of angiosarcoma, 38 cases of epithelioid hemangioendothelioma and 1 case of hepatic Kaposi's sarcoma...
November 8, 2017: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/29113263/artesunate-inhibits-proliferation-and-invasion-of-mouse-hemangioendothelioma-cells-in-vitro-and-of-tumor-growth-in-vivo
#5
Ning Wang, Hongxia Chen, Yinping Teng, Xionghui Ding, Huan Wu, Xianqing Jin
Artesunate has been demonstrated to be a novel potential antitumor agent in numerous studies. However, its efficacy in infantile hemangioma is unknown. The aim of the present study was to investigate the role of artesunate in the control of vascular tumor biological behavior and molecular mechanism using mouse hemangioendothelioma endothelial (EOMA) cells and a nude mouse model. Cell viability, apoptosis and invasion were determined by an MTT assay, flow cytometric analysis and Transwell invasion assay, respectively...
November 2017: Oncology Letters
https://www.readbyqxmd.com/read/29104110/pseudomyogenic-hemangioendothelioma-of-skin-bone-and-soft-tissue-a-clinicopathological-immunohistochemical-and-fluorescence-in-situ-hybridization-study
#6
Dinesh Pradhan, Karen Schoedel, Richard L McGough, Sarangarajan Ranganathan, Uma N M Rao
Pseudomyogenic hemangioendothelioma (PHE) is an uncommon neoplasm with propensity for local recurrence. The tumor mimics epithelioid hemangioendothelioma and epithelioid sarcoma, representing a possible diagnostic pitfall. We investigated the clinicopathological, immunohistochemical and fluorescence in situ hybridization features of PHEs. Eight cases of PHE were retrieved from our pathology archives. The clinical and outcome information was available in six patients. In six cases the tumors were located in the lower limb while the upper limb was involved in two cases...
November 2, 2017: Human Pathology
https://www.readbyqxmd.com/read/29054942/primary-hepatic-hemangioendothelioma-in-a-patient-with-budd-chiari-syndrome
#7
Preet Mukesh Shah, Vijay Waman Dhakre, Aabha Nagral
A 36-year-old woman was diagnosed with compensated cirrhosis of liver secondary to Budd-Chiari syndrome (BCS) and had undergone stenting of a thrombosed left hepatic vein. Eight months later, she presented with jaundice and right upper quadrant pain. CT revealed multiple focal lesions in the liver, which on biopsy proved to be hepatic hemangioendothelioma (HHE). Her liver disease and ascites progressively increased. Four months later, magnetic resonance cholangiopancreatography showed an advanced stage of HHE with infiltration of the common bile duct and vascular invasion with a blocked stent, with metastasis to the spleen and dorsolumbar vertebrae...
October 19, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29050802/episode-of-kasabach-merritt-phenomenon-following-japanese-encephalitis-vaccination-case-report
#8
Xiaojie Yue, Xiong Zhao, Yefeng Dai, Qiang Shu
Kasabach-Merritt phenomenon (KMP) is a rare potentially life-threatening consumptive coagulopathy characterized by thrombocytopenia and hypofibrinogenemia occurring associated with the vascular tumors kaposiform hemangioendothelioma (KHE) and tufted angioma (TA). A 10-month old male infant, diagnosed with KHE on his left leg, underwent a rapid increase of the lesion and severe thrombocytopenia, one day after the first dose of inactivated Japanese encephalitis (JE) vaccination. The episode of KMP was treated successfully by steroid...
October 16, 2017: Vaccine
https://www.readbyqxmd.com/read/29030282/epithelioid-hemangioendothelioma-an-uncommon-tumor-of-the-eyelid-a-case-report
#9
M A Ennouhi, A Guerrouani, A Moussaoui
Epithelioid hemangioendothelioma (EHE) is an infrequent vascular tumor that has an intermediate prognosis between the prognosis of the angioma and that of the angiosarcoma. Its evolution is characterized by a tendency to recurrence and metastases. EHE has been reported in locations such as: lungs, liver, bone and soft tissues. There are very few reports of cases involving the head and neck region. The occurrence of EHE in the orbital region and/or the eyelid is extremely rare. The authors report a case of EHE in the right upper eyelid...
October 11, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28989828/magnetic-resonance-imaging-of-primary-hepatic-malignancies-in-patients-with-and-without-chronic-liver-disease-a-pictorial-review
#10
REVIEW
Lauren F Alexander, Peter Harri, Brent Little, Courtney C Moreno, Pardeep K Mittal
Primary hepatic malignancies are less common than metastatic diseases, but a recognition of these lesions is important for diagnosis and treatment planning. Magnetic resonance imaging (MRI) provides the most imaging information to diagnose lesions noninvasively and to narrow differential diagnoses. This paper reviews the imaging findings of chronic liver disease and primary hepatic malignancies, including hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (CCA), epithelioid hemangioendothelioma, hepatic angiosarcoma, and primary hepatic lymphoma...
August 4, 2017: Curēus
https://www.readbyqxmd.com/read/28982854/clinicopathological-characteristics-of-ovarian-sclerosing-stromal-tumor-with-an-emphasis-on-tfe3-overexpression
#11
Cheol Keun Park, Hyun-Soo Kim
A sclerosing stromal tumor is a very rare benign sex cord-stromal tumor of the ovary. Because its clinical presentation and imaging findings are similar to those of borderline or malignant epithelial tumors and other sex cord-stromal tumors, accurate preoperative clinical diagnosis can be difficult. The aim of this study was to analyze the clinicopathological characteristics of SSTs and examine the immunohistochemical expression TFE3, which has not been studied in SSTs. Our study cohort consisted of 9 patients diagnosed as having SST; the median age was 36 years...
October 2017: Anticancer Research
https://www.readbyqxmd.com/read/28972580/composite-hemangioendothelioma-with-neuroendocrine-marker-expression-an-aggressive-variant
#12
Kyle D Perry, Alyaa Al-Lbraheemi, Brian P Rubin, Jin Jen, Hongzheng Ren, Jin Sung Jang, Asha Nair, Jaime Davila, Stefan Pambuccian, Andrew Horvai, William Sukov, Henry D Tazelaar, Andrew L Folpe
This corrects the article DOI: 10.1038/modpathol.2017.83.
October 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28969747/primary-pleural-epitheliod-hemangioendothelioma-with-lung-involvement
#13
Saima Siraj, Saima Akhter, Nadeem Rizvi
The authors report a case of 50-year man who presented with 2-year history of dry cough, right sided chest pain, and shortness of breath. Chest X-ray revealed right-sided pleural effusion and left-sided opacity. Pleuroscopic pleural biopsy confirmed the diagnosis of primary pleural epitheliod hemangioendothelioma (EHE) with peripheral lung parenchymal invasion. Chest drain was inserted; and significant amount of fluid was drained, but lung failed to expand after 72 hours. Patient was planned for video assisted thoracoscopy (VATS) and also discussed with oncology department for chemotherapy; but he refused any further treatment, and left home against medical advice with chest drain in place...
September 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28943201/-diagnostic-challenges-on-breast-needle-core-biopsies-case-6-epithelioid-hemangioendothelioma
#14
Noëlle Weingertner
No abstract text is available yet for this article.
October 2017: Annales de Pathologie
https://www.readbyqxmd.com/read/28906349/intestinal-obstruction-due-to-kaposiform-hemangioendothelioma-in-a-1-month-old-infant-a-case-report
#15
Joong Kee Youn, Shin-Hoo Park, Ji-Won Han, Chaeyoun Oh, Hyun-Young Kim, Sung-Eun Jung
RATIONALE: Kaposiform hemangioendothelioma (KHE) is an aggressive vascular tumor, mainly occurring in infants and young children and previously reported cases were mainly cutaneous or visceral form. Intestinal kaposiform hemangioma was first reported in 2012. Intestinal type KHE showed better prognosis if the lesion was limited in the gastrointestinal tract and coagulopathy was not accompanied. Since the number of reported cases is small, further study for treatment options and prognosis need to be done...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28898344/-lung-epithelioid-hemangioendothelioma-report-of-one-case
#16
Manuel Quiroz, Álvaro Undurraga, Rafael Moya, Cristina Fernández, Katiuska Bezares, Virginia Linacre
Epithelioid hemangioendothelioma is a multifocal tumor that rarely metastasizes. It is difficult to diagnose, most often it is an incidental finding in young asymptomatic women. The radiologic pattern is heterogeneous. Histologic confirmation of Weibel-Palade bodies or immunohistochemistry based on specific tumor markers such as factor VIII and CD34 are the most important finding to confirm the diagnosis. We report a 21 years old woman Presenting with cough and dyspnea. A chest X ray was suggestive of tuberculosis...
May 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28884037/new-insights-about-pulmonary-epithelioid-hemangioendothelioma-review-of-the-literature-and-two-case-reports
#17
Romeu Duarte Mesquita, Marta Sousa, Carmen Trinidad, Eugénia Pinto, Iosu Antón Badiola
Pulmonary epithelioid hemangioendothelioma (PEH) is a rare neoplasm of vascular origin. There are three different major imaging patterns identified in thoracic manifestation of epithelioid hemangioendothelioma: (1) multiple pulmonary nodules; (2) multiple pulmonary reticulonodular opacities; and (3) diffuse infiltrative pleural thickening. Radiographically, presence of bilateral multiple nodules is the most common pattern of presentation. The diagnosis is made on the basis of histopathological findings and confirmed by positive immunohistochemistry staining...
2017: Case Reports in Radiology
https://www.readbyqxmd.com/read/28881518/-refractory-kaposiform-hemangioendothelioma-with-kasabach-merritt-syndrome-clinical-analysis-of-10-cases
#18
G L Zhang, Y Gao, Y Liu, F Gu, W Su, Q Qin, J Y Chen, H H Zhang, J Yang, X Y Liu
Objective: To analyze the clinical value of sirolimus plus prednisone for the treatment of the refractory kaposiform hemangioendothelioma(RKHE) and Kasabach-Merritt syndrome(KMS). Method: Clinical retrospective analysis was carried out for 10 patients recruited in Children's Hospital Affiliated to Capital Institute of Paediatrics from January 2014 to January 2017 who were non responders to or relapsers after the treatment of propranolol, prednisone, pingyangmycin and lauromacrogol(5 cases RKHE, 5 cases RKHE plus KMS, age ranged from 6 days to 9 years); patients were treated with sirolimus at the dosage of 0...
September 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28879422/differentiating-primary-hepatic-angiosarcomas-from-hemangiomatosis-and-epithelioid-hemangioendotheliomas-using-gadoxetic-acid-enhanced-and-diffusion-weighted-mr-imaging
#19
Jung Wook Seo, Seong Hyun Kim, Ah Yeong Kim, Woo Kyoung Jeong, Ji Young Woo, Won Jeong Park
OBJECTIVES: To assess the value of gadoxetic acid-enhanced and diffusion-weighted (DW) magnetic resonance (MR) imaging for differentiating primary hepatic angiosarcomas from hemangiomatosis and epithelioid hemangioendotheliomas (EHEs). METHODS: We reviewed MR images of seven patients with pathologically determined hepatic angiosarcomas, 11 patients with hemangiomatosis, and five patients with EHEs. Two radiologists assessed morphologic features, signal intensity (SI), enhancement patterns, and the presence of diffusion restriction by consensus and compared between angiosarcoma vs hemangiomatosis and angiosarcoma vs EHEs...
November 2017: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/28872546/68ga-dota-tate-pet-ct-for-molecular-imaging-of-somatostatin-receptor-expression-in-metastasizing-epithelioid-hemangioendothelioma-comparison-with-18f-fdg
#20
Thorsten Derlin, Katja Hueper, Bisharah Soudah
Epithelioid hemangioendothelioma (EHE) is a rare tumor originating from vascular endothelial or pre-endothelial cells. It has the potential to metastasize. We present the case of a 51-year-old woman with metastasizing EHE who underwent both F-FDG and Ga-DOTA-TATE PET/CT for staging of disease and for evaluation of targeted radionuclide therapy potential. On Ga-DOTA-TATE PET scans, intense tracer accumulation was observed in metastases. Besides the increased glucose metabolism in EHE, this case highlights the potential of Ga-DOTA-TATE PET/CT for restaging of EHE and the option of targeted radionuclide therapy in this entity...
September 1, 2017: Clinical Nuclear Medicine
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