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https://www.readbyqxmd.com/read/29909519/growth-performance-and-plasma-metabolites-in-juvenile-siberian-sturgeon-acipenser-baerii-brandt-1869-subjected-to-various-feeding-strategies-at-different-sizes
#1
Naghmeh Jafari, Bahram Falahatkar, Mir Masoud Sajjadi
The effect of various feeding strategies was evaluated on growth performance and biochemical parameters in two sizes of Siberian sturgeon (465.75 ± 11.18 and 250.40 ± 12 g) during 45 days. Fish were distributed into six experimental treatments including large fish with satiation feeding (LA), small fish with satiation feeding (SA), large fish with 50% satiation feeding (LR), small fish with 50% satiation feeding (SR), large starved fish (LS), and small starved fish (SS). Differences in final weight between LA and LR treatments were not noticeable, whereas SA and SR treatments showed significant differences...
June 16, 2018: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/29909269/can-uterocervical-angles-successfully-predict-induction-of-labor-in-nulliparous-women
#2
Emrah Dagdeviren, Berna Aslan Çetin, Begum Aydogan Mathyk, Nadiye Koroglu, Elif Goknur Topcu, Mehmet Aytac Yuksel
PURPOSE: Induction of labor is a common practice in obstetrics. In recent years, a newer ultrasonographic parameter called the uterocervical angle (UCA) has been identified as a predictive tool for births. Our purpose is to investigate the role of UCA in predicting successful induction of labor. METHODS: The nulliparous term pregnancies (n:150) were grouped into successful/failed inductions of labor based on their progress into the active phase of labor after the administration of prostaglandin E2 (dinoprostone)...
June 11, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29909091/clinical-and-pharmacogenetic-determinants-of-5-fluorouracyl-leucovorin-irinotecan-toxicity-results-of-the-petacc-3-trial
#3
Sabine Tejpar, Pu Yan, Hubert Piessevaux, Daniel Dietrich, Peter Brauchli, Dirk Klingbiel, Roberto Fiocca, Mauro Delorenzi, Fred Bosman, Arnaud D Roth
PURPOSE: Irinotecan (CPT-11) in combination with 5-fluorouracil (5FU) is widely used in the treatment of colorectal cancer. We assessed potential clinical variables that may predict toxicity and more specifically the role of UGT1A1 polymorphisms associated with irinotecan toxicity. We used data from the PETACC3 trial, which randomised patients in adjuvant setting to 6 months of leucovorin (LV) and 5FU (LV5/FU2) or LV5/FU2 + irinotecan. PATIENTS AND METHODS: Clinical and toxicity data were available for 2982 patients, DNA was available for 1200 (40%) of these patients...
June 14, 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29909084/clinical-outcomes-in-the-treatment-of-unilateral-condylar-fractures-a-cross-sectional-study
#4
A V J Rozeboom, L T Klumpert, M Koutris, L Dubois, C M Speksnijder, F Lobbezoo, J de Lange
The treatment of mandibular condyle fractures has been the subject of considerable discussion, especially whether open or closed treatment should be used. There is a need for practical,evidence-based guidelines, and both objective and subjective parameters should be measured. To date, fewstudies have considered clinically relevant subjective parameters. This study was performed to evaluate the outcomes of the treatment of condylar fractures using the Mandibular Function Impairment Questionnaire (MFIQ) and the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) and to compare the outcomes of open and the closed treatment...
June 13, 2018: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29908878/marked-prognostic-impact-of-minimal-lymphatic-tumor-spread-in-prostate-cancer
#5
Waldemar Wilczak, Corinna Wittmer, Till Clauditz, Sarah Minner, Stefan Steurer, Franziska Büscheck, Till Krech, Maximilian Lennartz, Luisa Harms, Diane Leleu, Marc Ahrens, Sebastian Ingwerth, Christian T Günther, Christina Koop, Ronald Simon, Frank Jacobsen, Maria C Tsourlakis, Viktoria Chirico, Doris Höflmayer, Eik Vettorazzi, Alexander Haese, Thomas Steuber, Georg Salomon, Uwe Michl, Lars Budäus, Derya Tilki, Imke Thederan, Christoph Fraune, Cosima Göbel, Marie-Christine Henrich, Manuela Juhnke, Katharina Möller, Ahmed Abdullah Bawahab, Ria Uhlig, Meike Adam, Sören Weidemann, Burkhard Beyer, Hartwig Huland, Markus Graefen, Guido Sauter, Thorsten Schlomm
BACKGROUND: Nodal metastasis (N1) is a strong prognostic parameter in prostate cancer; however, lymph node evaluation is always incomplete. OBJECTIVE: To study the prognostic value of lymphatic invasion (L1) and whether it might complement or even replace lymph node analysis in clinical practice. DESIGN, SETTING, AND PARTICIPANTS: Retrospective analysis of pathological and clinical data from 14 528 consecutive patients. INTERVENTION: Radical prostatectomy...
June 13, 2018: European Urology
https://www.readbyqxmd.com/read/29908775/insulin-resistance-is-associated-with-depression-risk-in-polycystic-ovary-syndrome
#6
Eleni A Greenwood, Lauri A Pasch, Marcelle I Cedars, Richard S Legro, Esther Eisenberg, Heather G Huddleston
OBJECTIVE: To test the hypothesis that insulin resistance is associated with depression risk in polycystic ovary syndrome (PCOS). DESIGN: Secondary analysis of data from a multicenter randomized trial. SETTING: Multicenter university-based clinical practices. PATIENT(S): Seven hundred thirty-eight women with PCOS by modified Rotterdam criteria seeking pregnancy enrolled in a randomized clinical trial comparing clomiphene citrate versus letrozole...
June 13, 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29908640/comparative-study-of-regenerative-effects-of-mesenchymal-stem-cells-derived-from-placental-amnion-chorion-and-umbilical-cord-on-dermal-wounds
#7
Juliane Ertl, Melanie Pichlsberger, Alexandru-Cristian Tuca, Paul Wurzer, Jakob Fuchs, Stefan H Geyer, Barbara Maurer-Gesek, Wolfgang J Weninger, Dagmar Pfeiffer, Vladimir Bubalo, Daryousch Parvizi, Lars-Peter Kamolz, Ingrid Lang
OBJECTIVE: Mesenchymal stem/stromal cells derived from human term placentas (PMSCs) are novel therapeutic agents and more topical than ever. Here we evaluated the effects of three types of PMSCs on wound healing in an in vivo mouse model: Amnion-derived MSCs (AMSCs), blood vessel-derived MSCs (BV-MSCs) from the chorionic plate and Wharton's jelly-derived MSCs (WJ-MSCs) from the umbilical cord. METHODS: We topically applied PMSCs onto skin wounds in mice using the dermal substitute Matriderm® as carrier and evaluated wound healing parameters...
May 2018: Placenta
https://www.readbyqxmd.com/read/29908616/primary-care-for-the-transgender-and-gender-nonconforming-patient
#8
REVIEW
Frederic M Ettner
All physicians are likely to encounter gender diverse patients, and some of these patients require medically necessary surgical procedures. It is optimal for surgeons to collaborate with other providers who interact with this patient population. Primary care physicians initiate treatment with consultation from mental health professionals and refer to surgeons when necessary. Best practices consist of preventative care, hormone therapy induction when indicated, monitoring of all health parameters, and continuing care medically and postoperatively...
July 2018: Clinics in Plastic Surgery
https://www.readbyqxmd.com/read/29908500/new-approach-for-point-pollution-source-identification-in-rivers-based-on-the-backward-probability-method
#9
Jiabiao Wang, Jianshi Zhao, Xiaohui Lei, Hao Wang
Pollution risk from the discharge of industrial waste or accidental spills during transportation poses a considerable threat to the security of rivers. The ability to quickly identify the pollution source is extremely important to enable emergency disposal of pollutants. This study proposes a new approach for point source identification of sudden water pollution in rivers, which aims to determine where (source location), when (release time) and how much pollutant (released mass) was introduced into the river...
June 13, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29908367/cell-proliferation-and-anti-apoptosis-essential-processes-for-recruitment-of-the-full-thermogenic-capacity-of-brown-adipose-tissue
#10
REVIEW
Jan Nedergaard, Yanling Wang, Barbara Cannon
In mice living under normal animal house conditions, the brown adipocytes in classical brown adipose tissue depots are already essentially fully differentiated: UCP1 mRNA and UCP1 protein levels are practically saturated. This means that any further recruitment - in response to cold exposure or any other browning agent - does not result in significant augmentation of these parameters. This may easily be construed to indicate that classical brown adipose tissue cannot be further recruited. However, this is far from the case: the capacity for further recruitment instead lies in the ability of the tissue to increase the number of brown-fat cells, a remarkable and highly controlled physiological recruitment process...
June 13, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29908062/validation-of-the-acuros-xb-dose-calculation-algorithm-versus-monte-carlo-for-clinical-treatment-plans
#11
Lone Hoffmann, Markus Alber, Matthias Söhn, Ulrik Vindelev Elstrøm
PURPOSE: The two distinct dose computation paradigms of Boltzmann Equation Solvers and Monte Carlo simulation both promise in principle maximum accuracy. In practice, clinically acceptable calculation times demand approximations and numerical short-cuts on one hand, and modelling the beam characteristics of a real linear accelerator to the required accuracy on the other. A thorough benchmark of both algorithm types therefore needs to start with beam modelling, and needs to include a number of clinically challenging treatment plans...
June 16, 2018: Medical Physics
https://www.readbyqxmd.com/read/29907287/low-cost-scholl-coupling-microporous-polymer-as-an-efficient-solid-phase-microextraction-coating-for-the-detection-of-light-aromatic-compounds
#12
Xintong Xie, Junhui Wang, Juan Zheng, Junlong Huang, Chuyi Ni, Jie Cheng, Zhengping Hao, Gangfeng Ouyang
A cost-effective microporous polymer was synthesized using cheap monomer and catalyst via one-step Scholl-coupling reaction, and its chemical, morphological characteristics and pore structure were investigated. The as-synthesized polymer with large surface area and narrow pore distribution (centered in 1.2 nm) was prepared as a fiber coating for solid-phase microextraction (SPME). Headspace SPME was used for the extraction of the light aromatic compounds, e.g. benzene, toluene, ethylbenzene, m-xylene, naphthalene and acenaphthene...
October 31, 2018: Analytica Chimica Acta
https://www.readbyqxmd.com/read/29907274/a-targeted-management-approach-to-cardiogenic-shock
#13
REVIEW
Mithun Chakravarthy, Masaki Tsukashita, Srinivas Murali
Cardiogenic shock is a clinical syndrome characterized by low cardiac output and sustained tissue hypoperfusion resulting in end-organ dysfunction and death. In-hospital mortality rates range from 50% to 60%. Urgent diagnosis, timely transfer to a tertiary or quaternary medical facility with critical care management capabilities and multidisciplinary shock teams is a must to increase survival. Aggressive, hemodynamically guided medical management with careful monitoring of clinical and hemodynamic parameters with timely use of appropriate mechanical circulatory support devices is often necessary...
July 2018: Critical Care Clinics
https://www.readbyqxmd.com/read/29906622/effects-of-dietary-soybean-lecithin-on-growth-performance-blood-chemistry-and-immunity-in-juvenile-stellate-sturgeon-acipenser-stellatus
#14
Fatemeh Jafari, Naser Agh, Farzaneh Noori, Amir Tokmechi, Enric Gisbert
An eleven weeks feeding trial was conducted to determine the effects of different levels of dietary soybean lecithin (SBL) on growth performance, blood chemistry and immunity in juvenile stellate sturgeon (Acipenser stellatus). Fish were fed seven isoproteic (44% crude protein) and isolipidic (17% crude fat) diets containing graded levels of SBL: 0 (control), 1, 2, 4, 6, 8 and 10%. Results showed that dietary SBL supplementation significantly improved the final body weight (BW) and weight gain (WG). Fish fed 6% SBL showed the highest BW and WG values in comparison to fish fed the control diet (P < 0...
June 12, 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29906519/towards-bend-contour-free-dislocation-imaging-via-diffraction-contrast-stem
#15
Yuanyuan Zhu, Colin Ophus, Mychailo B Toloczko, Danny J Edwards
Dislocation imaging using transmission electron microscopy (TEM) has been an invaluable tool for characterizing crystallographic defects in metals. Compared to conventional TEM imaging, diffraction contrast imaging scanning transmission electron microscopy (DCI STEM) with appropriate setting can provide better defect contrast with almost negligible bend contour artifacts, enabling more effective analysis of dislocation structures. Here, we investigated why STEM can suppresses bend contour, and how dislocation contrast behaves along with different STEM imaging parameters...
June 7, 2018: Ultramicroscopy
https://www.readbyqxmd.com/read/29906276/bias-due-to-differential-and-non-differential-disease-and-exposure-misclassification-in-studies-of-vaccine-effectiveness
#16
Tom De Smedt, Elizabeth Merrall, Denis Macina, Silvia Perez-Vilar, Nick Andrews, Kaatje Bollaerts
BACKGROUND: Studies of vaccine effectiveness (VE) rely on accurate identification of vaccination and cases of vaccine-preventable disease. In practice, diagnostic tests, clinical case definitions and vaccination records often present inaccuracies, leading to biased VE estimates. Previous studies investigated the impact of non-differential disease misclassification on VE estimation. METHODS: We explored, through simulation, the impact of non-differential and differential disease- and exposure misclassification when estimating VE using cohort, case-control, test-negative case-control and case-cohort designs...
2018: PloS One
https://www.readbyqxmd.com/read/29906270/effect-of-different-esthetic-post-core-materials-on-color-of-direct-composite-restorations-a-preliminary-clinical-study
#17
Buket Ayna, Berivan D Yılmaz, Bozan S Izol, Emrah Ayna, İbrahim Halil Tacir
BACKGROUND The purpose of this study was to determine the influence of 2 different esthetic post materials on the final color of direct-composite restorations by using a digital technique under in vivo conditions. MATERIAL AND METHODS We included 22 pulpless incisor teeth treated with conventionally cemented zirconia (n=11) and polyethylene fiber (n=11) posts in the study. Teeth were restored with a hybrid resin. The color of direct-composite restorations and contralateral control teeth was measured using a digital technique...
June 15, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29905545/-a-comparative-evaluation-of-the-effect-of-dentures-from-various-materials-on-the-oral-cavity-s-immunological-and-redox-dependent-homeostasis
#18
Z Nakudashvili, I Mgebrishvili, I Barbakadze, T Sanikidze
The purpose of our study was a comparative analysis of the effect of dentures from various materials on the immunological and redox-dependent homeostasis of the oral cavity. We studied 60 patients with removable dentures made based on plastics Prothyl Hot, Vertex BasiQ 20 (differing by polymerization regime) and elastic thermoplastic polymer Perflex Flexi Nylon. The control group consisted of 15 volunteers with a practically healthy oral cavity, who did not use dentures. Saliva collected on an empty stomach in a glass tube without the use of a stimulator before the establishment of a denture and 3 days and 1 month after...
May 2018: Georgian Medical News
https://www.readbyqxmd.com/read/29904634/dietary-walnuts-protect-against-obesity-driven-intestinal-stem-cell-decline-and-tumorigenesis
#19
Fangxia Guan, Tahmineh Tabrizian, Ardijana Novaj, Masako Nakanishi, Daniel W Rosenberg, Derek M Huffman
Obesity can negatively impact intestinal homeostasis, and increase colon cancer risk and related mortality. Thus, given the alarmingly high rates of obesity in the US and globally, it is critical to identify practical strategies that can break the obesity-cancer link. Walnuts have been increasingly recognized to mitigate cancer risk, and contain many bioactive constituents with antioxidant and anti-inflammatory properties that could potentially counteract pathways thought to be initiators of obesity-related cancer...
2018: Frontiers in Nutrition
https://www.readbyqxmd.com/read/29904336/magnitude-and-temporal-variability-of-inter-stimulus-eeg-modulate-the-linear-relationship-between-laser-evoked-potentials-and-fast-pain-perception
#20
Linling Li, Gan Huang, Qianqian Lin, Jia Liu, Shengli Zhang, Zhiguo Zhang
The level of pain perception is correlated with the magnitude of pain-evoked brain responses, such as laser-evoked potentials (LEP), across trials. The positive LEP-pain relationship lays the foundation for pain prediction based on single-trial LEP, but cross-individual pain prediction does not have a good performance because the LEP-pain relationship exhibits substantial cross-individual difference. In this study, we aim to explain the cross-individual difference in the LEP-pain relationship using inter-stimulus EEG (isEEG) features...
2018: Frontiers in Neuroscience
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