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https://www.readbyqxmd.com/read/28529664/patient-specific-3d-models-aid-planning-for-triplane-proximal-femoral-osteotomy-in-slipped-capital-femoral-epiphysis
#1
L Cherkasskiy, J P Caffrey, A F Szewczyk, E Cory, J D Bomar, C L Farnsworth, M Jeffords, D R Wenger, R L Sah, V V Upasani
PURPOSE: Slipped capital femoral epiphysis (SCFE) can result in a complex three-dimensional (3D) deformity of the proximal femur. A three-plane proximal femoral osteotomy (TPFO) has been described to improve hip mechanics. The purpose of this study was to evaluate the benefits of using 3D print technology to aid in surgical planning. PATIENTS AND METHODS: Fifteen children treated with TPFO for symptomatic proximal femoral deformity due to SCFE were included in this study...
April 2017: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/28528863/cross-linking-of-a-biopolymer-peptide-co-assembling-system
#2
Karla E Inostroza-Brito, Estelle C Collin, Anna Poliniewicz, Sherif Elsharkawy, Alistair Rice, Armando E Del Río Hernández, Xin Xiao, José Rodríguez-Cabello, Alvaro Mata
The ability to guide molecular self-assembly at the nanoscale into complex macroscopic structures could enable the development of functional synthetic materials that exhibit properties of natural tissues such as hierarchy, adaptability, and self-healing. However, the stability and structural integrity of these kinds of materials remains a challenge for many practical applications. We have recently developed a dynamic biopolymer-peptide co-assembly system with the capacity to grow and undergo morphogenesis into complex shapes...
May 18, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28528229/sensitive-uhplc-ms-ms-quantitation-and-pharmacokinetic-comparisons-of-multiple-alkaloids-from-fuzi-beimu-and-single-herb-aqueous-extracts-following-oral-delivery-in-rats
#3
Yanyan Xu, Yamei Li, Pengjie Zhang, Bin Yang, Huanyu Wu, Xuejun Guo, Yubo Li, Yanjun Zhang
Aconiti Lateralis Radix Praeparata- Fritillariae Thunbergii bulbus, namely Fuzi- Beimu in Chinese, is a classic herb pair whose combined administration was prohibited according to the rule of "Eighteen antagonisms". However, incompatibility of Fuzi and Beimu has become controversial because of the application supported by many recorded ancient prescriptions and increasing modern researches and clinical practice. The present study aimed to investigate the pharmacokinetic differences of multiple alkaloids from Fuzi- Beimu and the single herb aqueous extracts following oral delivery in rats...
May 15, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28528147/variability-and-reproducibility-of-segmental%C3%A2-longitudinal-strain-measurement-a-report-from-the-eacvi-ase-strain-standardization-task%C3%A2-force
#4
Oana Mirea, Efstathios D Pagourelias, Jurgen Duchenne, Jan Bogaert, James D Thomas, Luigi P Badano, Jens-Uwe Voigt
OBJECTIVES: In this study, we compared left ventricular (LV) segmental strain measurements obtained with different ultrasound machines and post-processing software packages. BACKGROUND: Global longitudinal strain (GLS) has proven to be a reproducible and valuable tool in clinical practice. Data about the reproducibility and intervendor differences of segmental strain measurements, however, are missing. METHODS: We included 63 volunteers with cardiac magnetic resonance-proven infarct scar with segmental LV function ranging from normal to severely impaired...
May 12, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28528093/kinetic-and-thermodynamic-compensation-a-current-and-practical-review-for-foods
#5
REVIEW
Alfonso Garvín, Raquel Ibarz, Albert Ibarz
Kinetic and thermodynamic compensations have been reported in many chemical, physical, biological and food processes. Kinetic compensation can be found for any process and when it takes place, it gives information about the reaction mechanism and whether the reaction is controlled by enthalpy or entropy. It consists of the linear relationship between the logarithm of the frequency factor (lnk0) and the activation energy (Ea), both previously obtained from the Arrhenius equation for different values of an environmental variable (e...
June 2017: Food Research International
https://www.readbyqxmd.com/read/28528092/structural-strength-analysis-of-amorphous-trehalose-maltodextrin-systems
#6
V A Maidannyk, B Nurhadi, Y H Roos
Fundamental knowledge of physical state of materials gives practically important information for food, biological and pharmaceutical industry. Based on Williams-Landel-Ferry (WLF) equation, the strength concept was introduced. This concept provides a simple parameter, S, to express resistance of solids to flow above the glass transition temperature. To develop this approach, miscible trehalose-maltodextrin (0:100; 20:80; 40:60; 60:40; 80:20 and 100:0) systems with different ratios of components were used in the present study...
June 2017: Food Research International
https://www.readbyqxmd.com/read/28527448/estimating-thermodynamic-expectations-and-free-energies-in-expanded-ensemble-simulations-systematic-variance-reduction-through-conditioning
#7
Manuel Athènes, Pierre Terrier
Markov chain Monte Carlo methods are primarily used for sampling from a given probability distribution and estimating multi-dimensional integrals based on the information contained in the generated samples. Whenever it is possible, more accurate estimates are obtained by combining Monte Carlo integration and integration by numerical quadrature along particular coordinates. We show that this variance reduction technique, referred to as conditioning in probability theory, can be advantageously implemented in expanded ensemble simulations...
May 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28525655/genetic-parameters-and-path-analysis-in-cowpea-genotypes-grown-in-the-cerrado-pantanal-ecotone
#8
K V Lopes, P E Teodoro, F A Silva, M T Silva, R L Fernandes, T C Rodrigues, T C Faria, A M Corrêa
Estimating genetic parameters in plant breeding allows us to know the population potential for selecting and designing strategies that can maximize the achievement of superior genotypes. The objective of this study was to evaluate the genetic potential of a population of 20 cowpea genotypes by estimating genetic parameters and path analysis among the traits to guide the selection strategies. The trial was conducted in randomized block design with four replications. Its morphophysiological components, components of green grain production and dry grain yield were estimated from genetic use and correlations between the traits...
May 18, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28524885/ocular-surface-analysis-in-hematological-patients-before-and-after-allogeneic-hematopoietic-stem-cell-transplantation-implication-for-daily-clinical-practice
#9
G Giannaccare, F Bonifazi, M Sessa, E Dan, M Arpinati, M Fresina, G Bandini, M Cavo, P Versura, E C Campos
PurposeTo evaluate ocular surface parameters before and after hematopoietic stem cell transplantation (HSCT) and to correlate them with clinical and transplant variables.MethodsThis is a retrospective analysis of data from 93 patients affected by hematological malignancies undergoing HSCT. Values from Ocular Surface Disease Index, Schirmer test, Break-up Time, ocular surface staining, and Meibomian Gland Dysfunction score obtained before HSCT and 3-6 months after were retrieved from charts. Diagnosis and staging of dry eye (DE) disease was performed according to Dry Eye WorkShop criteria...
May 19, 2017: Eye
https://www.readbyqxmd.com/read/28524757/wood-smoke-exposure-of-portuguese-wildland-firefighters-dna-and-oxidative-damage-evaluation
#10
Ana Abreu, Carla Costa, Susana Pinho E Silva, Simone Morais, Maria do Carmo Pereira, Adília Fernandes, Vanessa Moraes de Andrade, João Paulo Teixeira, Solange Costa
Portugal is among the European Union countries most devastated by forest fires each year. In the last three decades, more than 3.8 million hectares of forest were burned. Wildland firefighters are exposed to a variety of hazards, including many toxic combustion products that may lead to deleterious health effects. Epidemiological studies showed a positive association between firefighting and several chronic diseases, including cancer. Results from biomonitoring studies in firefighters, particularly concerning genotoxicity evaluation, constitute a valuable tool for investigating important occupational hazards...
May 19, 2017: Journal of Toxicology and Environmental Health. Part A
https://www.readbyqxmd.com/read/28524112/optimal-fusion-estimation-with-multi-step-random-delays-and-losses-in-transmission
#11
Raquel Caballero-Águila, Aurora Hermoso-Carazo, Josefa Linares-Pérez
This paper is concerned with the optimal fusion estimation problem in networked stochastic systems with bounded random delays and packet dropouts, which unavoidably occur during the data transmission in the network. The measured outputs from each sensor are perturbed by random parameter matrices and white additive noises, which are cross-correlated between the different sensors. Least-squares fusion linear estimators including filter, predictor and fixed-point smoother, as well as the corresponding estimation error covariance matrices are designed via the innovation analysis approach...
May 18, 2017: Sensors
https://www.readbyqxmd.com/read/28524033/-procedural-analysis-of-acid-base-balance-disorder-case-serials-in-4-patents
#12
Chunyuan Ma, Guijie Wang
OBJECTIVE: To establish the standardization process of acid-base balance analysis, analyze cases of acid-base balance disorder with the aid of acid-base balance coordinate graph. METHODS: The acid-base balance theory were reviewed systematically on recent research progress, and the important concepts, definitions, formulas, parameters, regularity and inference in the analysis of acid-base balance were studied. The analysis of acid-base balance disordered processes and steps were figured...
May 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28523827/statistical-model-based-hplc-analytical-method-adjustment-strategy-to-adapt-to-different-sets-of-analytes-in-complicated-samples
#13
Binjun Yan, Xue Bai, Yunjie Sheng, Fanzhu Li
INTRODUCTION: On account of the complicated compositions of the products like traditional Chinese medicines (TCMs) and functional foods, it is a common practice to determine different sets of analytes in the same product for different purposes. OBJECTIVE: To efficiently develop the corresponding HPLC methods, a statistical model based analytical method adjustment (SMB-AMA) strategy was proposed. METHODS: In this strategy, the HPLC data acquired with design of experiments methodology were efficiently utilised to build the retention models for all the analytes and interferences shown in the chromatograms with multivariate statistical modelling methods...
May 19, 2017: Phytochemical Analysis: PCA
https://www.readbyqxmd.com/read/28523764/self-care-behaviors-in-heart-failure
#14
Agueda Maria Ruiz Zimmer Cavalcante, Camila Takao Lopes, Evelise Fadini Reis Brunori, Elizabeth Swanson, Sue Ann Moorhead, Maria Márcia Bachion, Alba Lucia Bottura Leite de Barros
OBJECTIVE: To identify self-care behaviors, instruments, techniques, parameters for the assessment of self-care behaviors in people with heart failure, compare these behaviors with the indicators of the Nursing Outcomes Classification outcome, Self Management: Cardiac Disease. METHOD: Integrative literature review performed in Lilacs, Medline, CINAHL, and Cochrane, including publications from 2009 to 2015. One thousand six hundred ninety-one articles were retrieved from the search, of which 165 were selected for analysis...
May 18, 2017: International Journal of Nursing Knowledge
https://www.readbyqxmd.com/read/28522866/femtosecond-laser-fabrication-of-anatase-tio2-micro-nanostructures-with-chemical-oxidation-and-annealing
#15
Ting Huang, Jinlong Lu, Xin Zhang, Rongshi Xiao, Wuxiong Yang, Qiang Wu
The fabrication of nanoporous anatase TiO2 on a microstructured Ti base is achieved through an innovative hybrid fabrication method involving femtosecond laser ablation coupled with H2O2 oxidation and annealing. The anatase TiO2 micro-nanostructures have superior photocatalytic degradation of methyl orange due to enhanced light harvesting capacity and surface area. The photodegradation efficiency increases by a maximum of 80% compared to the nanoporous anatase TiO2 fabricated through H2O2 oxidation and annealing only (without femtosecond laser ablation)...
May 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28522789/efficacy-of-camera-sleeve-in-conveyance-of-conduits
#16
R Saranga Bharathi
BACKGROUND: Esophageal substitutes need conveyance from the abdomen into the neck for restoration of alimentary continuity. Reports suggest that the use of plastic camera sleeve may prove advantageous in restoring conveyance. This study aims to evaluate the practicability of this approach, specifically, in laparoscopy-assisted surgeries. METHODS: The efficacy of camera sleeve in conduit transposition was prospectively evaluated over 2 years. The following parameters were assessed: success/failure; time taken; blood loss; adequacy of length of the conduit delivered into the neck; conduit orientation; ease of procedure through different routes; conduit damage; complications; and drawbacks...
February 28, 2017: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/28521789/a-comparative-evaluation-of-genome-assembly-reconciliation-tools
#17
Hind Alhakami, Hamid Mirebrahim, Stefano Lonardi
BACKGROUND: The majority of eukaryotic genomes are unfinished due to the algorithmic challenges of assembling them. A variety of assembly and scaffolding tools are available, but it is not always obvious which tool or parameters to use for a specific genome size and complexity. It is, therefore, common practice to produce multiple assemblies using different assemblers and parameters, then select the best one for public release. A more compelling approach would allow one to merge multiple assemblies with the intent of producing a higher quality consensus assembly, which is the objective of assembly reconciliation...
May 18, 2017: Genome Biology
https://www.readbyqxmd.com/read/28521231/development-of-an-x-shape-airlift-photobioreactor-for-increasing-algal-biomass-and-biodiesel-production
#18
Hoang-Minh Pham, Ho Seok Kwak, Min-Eui Hong, Jeewon Lee, Won Seok Chang, Sang Jun Sim
The aim of this work was to develop a high efficient photobioreactor for increasing biomass and lipid production in microalgae by assessment of the hydrodynamic properties and kLa which are important parameters for improving the algal cultivation efficiency. We designed three different photobioreactors (H-Shape, X-Shape and serial-column). Among them, X-Shape showed the highest hydrodynamic properties and kLa for algal cultivation. Thus, we evaluated the biomass and the lipid production in a 20L scale-up X-Shape photobioreactor...
May 8, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28518214/immune-monitoring-as-prerequisite-for-transplantation-tolerance-trials
#19
REVIEW
Katayoun Behnam Sani, Birgit Sawitzki
Ever since its first application in clinical medicine, scientists have urged to induce tolerance towards foreign allogeneic transplants and thus avoid rejection by the recipient's immune system. This would circumvent chronic use of immunosuppressive drugs (IS) and thus avoid development of IS-induced side effects, which are contributing to the still unsatisfactory long-term graft and patient survival after solid organ transplantation. Although manifold strategies of tolerance induction have been described in preclinical models, only three therapeutic approaches have been successfully utilized in a still small number of patients...
May 18, 2017: Clinical and Experimental Immunology
https://www.readbyqxmd.com/read/28518049/red-blood-cell-storage-time-and-transfusion-current-practice-concerns-and-future-perspectives
#20
REVIEW
María García-Roa, María Del Carmen Vicente-Ayuso, Alejandro M Bobes, Alexandra C Pedraza, Ataúlfo González-Fernández, María Paz Martín, Isabel Sáez, Jerard Seghatchian, Laura Gutiérrez
Red blood cells (RBCs) units are the most requested transfusion product worldwide. Indications for transfusion include symptomatic anaemia, acute sickle cell crisis, and acute blood loss of more than 30% of the blood volume, with the aim of restoring tissue oxygen delivery. However, stored RBCs from donors are not a qualitative equal product, and, in many ways, this is a matter of concern in the transfusion practice. Besides donor-to-donor variation, the storage time influences the RBC unit at the qualitative level, as RBCs age in the storage bag and are exposed to the so-called storage lesion...
May 2017: Blood Transfusion, Trasfusione del Sangue
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