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https://www.readbyqxmd.com/read/28110176/the-management-of-hiv-in-pregnancy-a-10-year-experience
#1
Sonia F Raffe, Charlotte Savage, Louisa A Perry, Amie Patel, Tricia Keith, Richard Howell, Robert Bradley, Rob Bomont, Katy Fidler, Yvonne Gilleece
OBJECTIVE: The package of care to reduce HIV mother to child transmission (MTCT) has evolved significantly since trials of ante and intrapartum antiretroviral therapy (ART) in 1994. In the UK MTCT rate has fallen from 25.6% in the 1990s to 0.46%. We review the management of HIV in pregnancy in Brighton in the context of evolving guidelines. STUDY DESIGN: HIV, obstetric and neonatal notes of all HIV positive women, pregnant between 2003 and 2014, were reviewed. RESULTS: 97 pregnancies in 75 women were identified, resulting in 79 live births...
January 3, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28109290/characterizing-breast-conditions-at-an-open-access-breast-clinic-in-south-africa-a-model-that-is-more-than-cancer-care-for-a-resource-limited-setting
#2
Sarah Rayne, Naomi Lince-Deroche, Cheryl Hendrickson, Kate Shearer, Faith Moyo, Pam Michelow, Grace Rubin, Carol Benn, Cynthia Firnhaber
BACKGROUND: While most breast-related research focuses on cancer, presentation of symptomatic persons in non-screened environments requires understanding the spectrum of breast diseases so as to plan services in resource-constrained settings. This study presents the variety of breast disease managed at a government, open-access breast clinic in South Africa. METHODS: We performed a retrospective file review using a systematic random sample of patients 18 years and above presenting for breast care over a 14-month period...
January 21, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28108929/jaboya-sex-for-fish-a-qualitative-analysis-of-contextual-risk-factors-for-extramarital-partnerships-in-the-fishing-communities-in-western-kenya
#3
Zachary A Kwena, Chris A Shisanya, Elizabeth A Bukusi, Janet M Turan, Shari L Dworkin, Grace A Rota, Isaac J Mwanzo
Extramarital partnerships exacerbate high HIV prevalence rates in many communities in sub-Saharan Africa. We explored contextual risk factors and suggested interventions to reduce extramarital partnerships among couples in the fishing communities on Lake Victoria, Kenya. We conducted 12 focus group discussions with 9-10 participants each (N = 118) and 16 in-depth interviews (N = 16) with fishermen and their spouses. Couples who participated were consented and separated for simultaneous gender-matched discussions/interviews...
January 20, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/28107805/effectiveness-of-an-sms-based-maternal-mhealth-intervention-to-improve-clinical-outcomes-of-hiv-positive-pregnant-women
#4
Jesse Coleman, Kate C Bohlin, Anna Thorson, Vivian Black, Patricia Mechael, Josie Mangxaba, Jaran Eriksen
We conducted a retrospective study to investigate the effectiveness of an mHealth messaging intervention aiming to improve maternal health and HIV outcomes. Maternal health SMSs were sent to 235 HIV-infected pregnant women twice per week in pregnancy and continued until the infant's first birthday. The messages were timed to the stage of the pregnancy/infant age and covered maternal health and HIV-support information. Outcomes, measured as antenatal care (ANC) visits, birth outcomes and infant HIV testing, were compared to a control group of 586 HIV-infected pregnant women who received no SMS intervention...
January 20, 2017: AIDS Care
https://www.readbyqxmd.com/read/28107796/social-and-structural-factors-related-to-hiv-risk-among-truck-drivers-passing-through-the-iringa-region-of-tanzania
#5
Anjalee Kohli, Deanna Kerrigan, Heena Brahmbhatt, Samuel Likindikoki, Justin Beckham, Ard Mwampashi, Jessie Mbwambo, Caitlin E Kennedy
Truck drivers and their assistants have been identified as groups at higher risk for HIV infection. We sought to identify and describe the social and structural factors that may contribute to HIV risk among truck drivers who visit rest stops in Iringa, Tanzania, a region characterized by high levels of migration and mobility. This analysis was part of a comprehensive strategic assessment to examine HIV risk factors in Iringa. This analysis focuses on 11 in-depth interviews with truck drivers and a transport owner...
January 20, 2017: AIDS Care
https://www.readbyqxmd.com/read/28103834/depression-alcohol-use-and-intimate-partner-violence-among-outpatients-in-rural-uganda-vulnerabilities-for-hiv-stis-and-high-risk-sexual-behavior
#6
Susan M Kiene, Haruna Lule, Katelyn M Sileo, Kazi Priyanka Silmi, Rhoda K Wanyenze
BACKGROUND: Intimate partner violence (IPV), alcohol use, and depression are key vulnerabilities for HIV in Uganda, and taken together may have a synergistic effect on risk. Our objective was to investigate the associations between depression, IPV, and alcohol use and HIV-risk indicators among a sample of outpatients in rural Uganda, and the effect of co-occurrence of these factors on HIV-risk indicators. METHODS: In a structured interview we collected data on high-risk sexual behavior, depression symptoms, emotional and physical IPV, and alcohol use, as well as a blood sample for HIV and syphilis tests and a urine sample for chlamydia and gonorrhea tests from 325 male and female outpatients receiving provider-initiated HIV testing and counseling (PITC) at a public hospital outpatient clinic in rural Uganda...
January 19, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28102939/what-is-the-relationship-between-increased-access-to-haart-relationship-status-and-fertility-decisions-amongst-hiv-positive-women-a-literature-review-and-meta-analysis
#7
REVIEW
Abigail Burgess, Edward Purssell
AIMS AND OBJECTIVES: To investigate the relationship between fertility decisions, to have already had a child or to desire to have one in the future, and the prognostic factors of; access to antiretrovirals, the time since these became widely available (year of the study) and relationship status. BACKGROUND: There have been significant advances in the treatment of Human Immunodeficiency Virus (HIV) with the advent of antiretroviral therapy which has been used to successfully reduce the rate of mother to child transmission; leading researchers to hypothesise that HIV positive women may desire to have children more so now than in the past...
January 19, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28101813/a-multi-us-city-assessment-of-awareness-and-uptake-of-pre-exposure-prophylaxis-prep-for-hiv-prevention-among-black-men-and-transgender-women-who-have-sex-with-men
#8
Lisa A Eaton, Derrick D Matthews, Daniel D Driffin, Leigh Bukowski, Patrick A Wilson, Ron D Stall
The HIV epidemic among Black men and transgender women who have sex with men (BMTW) demands an urgent public health response. HIV point prevalence among this population ranges from 25 to 43%-a rate far exceeding any other group. Pre-exposure prophylaxis (PrEP) for HIV prevention is a very promising prevention tool; however, its full potential to slow the epidemic has yet to be realized. For the current study, random time-location sampling at Black Gay Pride Events was used to collect data from N = 1274 BMTW, from five US cities, reporting HIV-negative/unknown status...
January 18, 2017: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/28101036/anti-n-methyl-d-aspartate-receptor-encephalitis-in-hiv-infection
#9
Eunice Patarata, Vera Bernardino, Ana Martins, Rui Pereira, Conceição Loureiro, Maria Francisca Moraes-Fontes
Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a rare condition characterized by emotional and behavioral disturbances, dyskinesias, and extrapyramidal signs. It occurs in young women of reproductive age and is classically described as a paraneoplastic phenomenon. We present a 36-year-old, HIV-positive female who was admitted to the hospital in an acute confusional state, with a stiff posture, periods of motor agitation, and myoclonic jerks of the hands. Her mental state progressively deteriorated...
September 2016: Case Reports in Neurology
https://www.readbyqxmd.com/read/28100383/-hiv-antibody-detection-results-in-patients-seeking-medical-care-in-peking-union-medical-college-hospital-2003-2014
#10
X J Song, Z F Qiu, W Cao, J Xie, Z J Zhang, S X Xu, T S Li
Objective: To better understand the infection status of HIV in the patients seeking medical care in Peking Union Medical College Hospital. Methods: The HIV detection data of the patients in the hospital from 2003-2014 were collected for a statistical analysis with software SPSS 19.0. Results: A total of 715 421 patients were screened, and 1 012 (0.14%) patients were HIV positive, and HIV infection were confirmed in 776 (0.11%) patients by Western Blot testing. The detection rate of HIV infection increased from 0...
January 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28100068/prevalence-patterns-and-correlates-of-hiv-disclosure-among-tb-hiv-patients-initiating-antiretroviral-therapy-in-lesotho
#11
Eleanor Hayes-Larson, Yael Hirsch-Moverman, Suzue Saito, Koen Frederix, Blanche Pitt, Bridget Llang Maama, Andrea A Howard
Disclosure of HIV-positive status has important implications for patient outcomes and preventing HIV transmission, but has been understudied in TB-HIV patients. We assessed disclosure patterns and correlates of non-disclosure among adult TB-HIV patients initiating ART enrolled in the START Study, a mixed-methods cluster-randomized trial conducted in Lesotho, which evaluated a combination intervention package (CIP) versus standard of care. Interviewer-administered questionnaire data were analyzed to describe patterns of disclosure...
January 18, 2017: AIDS Care
https://www.readbyqxmd.com/read/28097617/rates-and-covariates-of-recent-sexual-and-physical-violence-against-hiv-infected-outpatient-drinkers-in-western-kenya
#12
Rebecca K Papas, Benson N Gakinya, Michael M Mwaniki, Hana Lee, Stella W Kiarie, Steve Martino, Michelle P Loxley, Alfred K Keter, Debra A Klein, John E Sidle, Joyce B Baliddawa, Stephen A Maisto
Victimization from physical and sexual violence presents global health challenges. Partner violence is higher in Kenya than Africa. Violence against drinkers and HIV-infected individuals is typically elevated, so dual vulnerabilities may further augment risk. Understanding violence risks can improve interventions. Participants were 614 HIV-infected outpatient drinkers in western Kenya enrolled in a randomized trial to reduce alcohol use. At baseline, past 90-day partner physical and sexual violence were examined descriptively and in gender-stratified regression models...
January 17, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28097445/pregnancy-outcomes-in-hiv-positive-women-a-retrospective-cohort-study
#13
Kholoud Arab, Andrea R Spence, Nicholas Czuzoj-Shulman, Haim A Abenhaim
PURPOSE: In the United States, an estimated 8500 HIV (human immunodeficiency virus) positive women gave birth in 2014. This rate appears to be increasing annually. Our objective is to examine obstetrical outcomes of pregnancy among HIV-positive women. METHODS: A population-based cohort study was conducted using the Nationwide Inpatient Sample database (2003-2011) from the United States. Pregnant HIV-positive women were identified and compared to pregnant women without HIV...
January 17, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28091842/squamous-cell-dysplasia-in-the-proximal-rectum-of-three-patients-treated-for-ulcerative-colitis-on-immunomodulators
#14
James G Connolly, Stephen E Goldstone
BACKGROUND: Anal canal high-grade squamous intraepithelial lesion (HSIL) is the precursor to anal cancer. Immunocompromised patients are at increased risk and disease is usually within 3 cm from the anal verge. High-resolution anoscopy (HRA) with an 8-cm anoscope is used to identify and guide cautery treatment of HSIL. PURPOSE: We report three patients with a long-term history of ulcerative colitis (UC) treated with systemic immunomodulators who developed proximally located rectal HSIL...
January 13, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28086933/self-collection-based-hpv-testing-for-cervical-cancer-screening-among-women-living-with-hiv-in-uganda-a-descriptive-analysis-of-knowledge-intentions-to-screen-and-factors-associated-with-hpv-positivity
#15
Sheona M Mitchell, Heather N Pedersen, Evelyn Eng Stime, Musa Sekikubo, Erin Moses, David Mwesigwa, Christine Biryabarema, Jan Christilaw, Josaphat K Byamugisha, Deborah M Money, Gina S Ogilvie
BACKGROUND: Women living with HIV (WHIV) are disproportionately impacted by cervical dysplasia and cancer. The burden is greatest in low-income countries where limited or no access to screening exists. The goal of this study was to describe knowledge and intentions of WHIV towards HPV self-collection for cervical cancer screening, and to report on factors related to HPV positivity among women who participated in testing. METHODS: A validated survey was administered to 87 HIV positive women attending the Kisenyi Health Unit aged 30-69 years old, and data was abstracted from chart review...
January 13, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28076637/a-five-year-review-of-vertical-hiv-transmission-in-a-specialized-service-cross-sectional-study
#16
Izabel Cristina Hoffmann, Wendel Mombaque Dos Santos, Stela Maris de Mello Padoin, Sonia Maria Oliveira de Barros
CONTEXT AND OBJECTIVE: Healthcare professionals need to instill the process of prevention, control and treatment of people infected with HIV into care practice. Through maintaining preventive treatment among HIV-infected pregnant women, it has been demonstrated that prophylactic antiretroviral therapy, scheduled cesarean section and the prohibition of breastfeeding significantly reduce vertical HIV transmission. This study aimed to assess the rates of vertical HIV transmission in a specialized service and identify the factors associated with it...
November 2016: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/28069056/determinants-of-fertility-desire-among-married-or-cohabiting-individuals-in-rakai-uganda-a-cross-sectional-study
#17
Joseph K B Matovu, Fredrick Makumbi, Rhoda K Wanyenze, David Serwadda
BACKGROUND: Recent trends in fertility rates indicate declines in total fertility rate (TFR) in some sub-Saharan African countries. However, countries such as Uganda continue to have a persistently high TFR partly attributed to strong preferences for large family sizes. We explored the factors that influence fertility desire among married or cohabiting individuals in Rakai, a rural district in southwestern Uganda. METHODS: This cross-sectional study of fertility desire (desire to have another child) was nested in a cluster-randomized demand-creation intervention trial for the promotion of couples' HIV counseling and testing uptake among married or cohabiting individuals that was conducted in Rakai district between March 1 and April 30, 2015...
January 10, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28068675/nutrition-habits-and-health-outcomes-of-breastfeeding-hiv-positive-mothers-in-the-dschang-health-district-west-region-cameroon
#18
Martin Sanou Sobze, Tsi Kien-Atsu, Bruna Djeunang Dongho, Jimmy Roger Fotso, Armand TiotsiaTsapi, Yannick Azeufack Ngueko, Sali Ben Bechir, Augusto Pana, Lucia Ercoli, Vittorio Colizzi, Gianluca Russo
BACKGROUND: Amongst the different at-risk periods for mother-to-child HIV transmission that is, during pregnancy, labor and delivery and breastfeeding, much care and attention needs to be given, not only to the child as concerns its feeding options, but also to the mother. The aim of this study was to determine the nutritional habits and health outcomes of HIV-positive breastfeeding mothers in the Dschang Health District, in the context of prevention of mother-to-child transmission (PMTCT) activities...
September 2016: Igiene e Sanità Pubblica
https://www.readbyqxmd.com/read/28064549/mother-to-child-transmission-of-human-immunodeficiency-virus-hiv-among-hiv-infected-pregnant-women-on-highly-active-anti-retroviral-therapy-with-premature-rupture-of-membranes-at-term
#19
George Uchenna Eleje, Emeka Stephen Edokwe, Joseph Ifeanyichukwu Ikechebelu, Chinyere Ukamaka Onubogu, Ebele Francesca Ugochukwu, Princeston Chukwuemeka Okam, Adaobi Maryann Ibekwe
PURPOSE: To determine mother-to-child transmission (MTCT) rate and associated risk factors of human immune-deficiency virus (HIV) among HIV-infected pregnant women with term premature rupture of membranes (PROM) in comparison with those without PROM at term. MATERIALS AND METHODS: All optimally managed HIV-positive pregnant women of Nnamdi Azikiwe University Teaching Hospital, on highly active anti-retroviral therapy (HAART) who had PROM at term were enrolled. Maternal HIV-1 viral load was not assessed...
January 8, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28060225/association-between-menopause-and-unprotected-sex-in-high-risk-hiv-positive-women-in-mombasa-kenya
#20
Marielle S Goyette, Kate S Wilson, Ruth Deya, Linnet N Masese, Juma Shafi, Barbra A Richardson, Kishorchandra Mandaliya, Walter Jaoko, R Scott McClelland
OBJECTIVE: Many HIV-positive women now live well beyond menopause. Postmenopausal women are no longer at risk for pregnancy, and some studies suggest they may use condoms less often than premenopausal women. This study tests the hypothesis that, in HIV-positive women who report trading sex for cash or in-kind payment, unprotected sex is more common at postmenopausal visits compared to premenopausal visits. DESIGN: Prospective cohort study of HIV-positive women ≥16 years old in Mombasa, Kenya...
December 30, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
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