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https://www.readbyqxmd.com/read/28634662/hiv-stigma-and-substance-use-among-hiv-positive-russians-with-risky-drinking
#1
E Jennifer Edelman, Karsten Lunze, Debbie M Cheng, Dmitry A Lioznov, Emily Quinn, Natalia Gnatienko, Carly Bridden, Christine E Chaisson, Alexander Y Walley, Evgeny M Krupitsky, Anita Raj, Jeffrey H Samet
The link between HIV stigma with substance use is understudied. We characterized individuals with high HIV stigma and examined whether HIV stigma contributes to substance use among HIV-positive Russians reporting risky alcohol use. We analyzed data from HERMITAGE, a randomized controlled trial of 700 people living with HIV/AIDS (PLWHA) with past 6-month risky sex and risky alcohol use in St. Petersburg, Russia (2007-2011). Participants who were female and reported depressive symptoms and lower social support were more likely to endorse high HIV stigma (all p's < 0...
June 20, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28629395/early-experiences-from-one-of-the-first-treatment-programs-for-chronic-hepatitis-b-in-sub-saharan-africa
#2
Hanna Aberra, Hailemichael Desalegn, Nega Berhe, Girmay Medhin, Kathrine Stene-Johansen, Svein Gunnar Gundersen, Asgeir Johannessen
BACKGROUND: Treatment for chronic hepatitis B (CHB) is virtually absent in sub-Saharan Africa. Here we present early experiences from a pilot program for treatment of CHB in Ethiopia. METHODS: Adults (≥18 years) with CHB were included in a cohort study at St. Paul's Hospital Millennium Medical College, Addis Ababa, from February 2015. The baseline assessment included liver function tests, viral markers and transient elastography (Fibroscan 402, Echosense, France)...
June 19, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28628854/prevalence-and-predictors-of-hcv-among-a-cohort-of-opioid-treatment-patients-in-dar-es-salaam-tanzania
#3
Barrot H Lambdin, Jennifer Lorvick, Jessie K Mbwambo, John Rwegasha, Saria Hassan, Paula Lum, Alex H Kral
BACKGROUND: The government of Tanzania launched an opioid treatment program (OTP), using methadone, in Dar es Salaam in February of 2011. Hepatitis C virus (HCV) is a leading cause of morbidity and mortality globally, especially among people who inject drugs (PWID). We conducted a cross-sectional study among PWID engaged in OTP in Dar es Salaam to describe the prevalence and predictors of HCV antibody serostatus. METHODS: Routine programmatic data on patients enrolled in Muhimbili National Hospital's OTP clinic from February 2011 to January 2013 were utilized...
June 16, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28627965/role-of-angiopoietin-2-endoglin-and-placental-growth-factor-in-hiv-associated-preeclampsia
#4
Nokuzola Mbhele, Jagidesa Moodley, Thajasvarie Naicker
OBJECTIVE: The factors angiopoeitin-2 (Ang-2), endoglin (Eng), and placental growth factor (PlGF) have been implicated in the pathophysiology of preeclampsia (PE). This study assessed their serum levels in HIV-negative and HIV-positive pregnant normotensive and pre-eclamptic women. METHODS: Participants were recruited at the antenatal clinic, serum samples were evaluated using the Bioplex Human Cancer Biomarker (panel 2). RESULTS: Ang-2 and Eng levels were higher, whilst PlGF levels were lower in the PE compared with the normotensive group...
June 19, 2017: Hypertension in Pregnancy
https://www.readbyqxmd.com/read/28623554/-obesity-high-blood-pressure-hypercholesterolaemia-and-untreated-diabetes-in-hiv-infected-and-hiv-uninfected-adults-in-mbuji-mayi-democratic-republic-of-congo
#5
D Mukeba-Tshialala, J B Nachega, M Mutombo-Tshingwali, V Arendt, G Gilson, M Moutschen
Little is known about the major cardiovascular risk factors in HIV-infected as compared to the HIV-uninfected patients in the Democratic Republic of Congo (DR Congo). We determined the prevalence of hypertension, obesity (BMI ≥ 30 kg/m(2)), total cholesterol > 200 mg/dl, HDL-cholesterol ≤ 40 mg/dl, and glycemia > 126 mg/dl. We also calculated the average and/or median of total cholesterol, HDL-cholesterol, and glycemia among HIV-infected and HIV-uninfected patients. We conducted a cross-sectional study that enrolled 592 HIV-uninfected and 445 HIV-infected patients of whom 425 (95...
June 16, 2017: Bulletin de la Société de Pathologie Exotique
https://www.readbyqxmd.com/read/28617372/-characteristics-of-psychopathological-symptomatology-in-hiv-infection-schizophrenic-patients
#6
D A Polyanskiy, V V Kalinin
AIM: To study the psychopathological structure of psychotic syndromes in HIV-infected schizophrenic patients and in patients without HIV infection. MATERIAL AND METHODS: Forty HIV-infected patients, 23 women and 17 men, with confirmed diagnosis of schizophrenia were included in the study. The control group consisted of 40 patients without HIV infection, 23 women (48%) and 17 men (52%). The psychopathological state in all patients was assessed with the PANSS. Flow cytometry was used to measure immunological parameters in HIV-infected patients...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28612214/factors-associated-with-mood-disorder-diagnosis-among-a-population-based-cohort-of-men-and-women-living-with-and-without-hiv-in-british-columbia-between-1998-and-2012
#7
Kalysha Closson, Chuck Osborne, Danielle M Smith, Sarah Kesselring, Oghenowede Eyawo, Kiffer Card, Paul Sereda, Shahab Jabbari, Conrado Franco-Villalobos, Tareq Ahmed, Karyn Gabler, Thomas Patterson, Mark Hull, Julio S G Montaner, Robert S Hogg
Using data from the Comparison of Outcomes and Service Utilization Trends (COAST) study we examined factors associated with mood disorder diagnosis (MDD) among people living with HIV (PLHIV) and HIV-negative individuals in British Columbia, Canada. MDD cases were identified between 1998 and 2012 using International Classification of Disease 9 and 10 codes. A total of 491,796 individuals were included and 1552 (23.7%) and 60,097 (12.4%) cases of MDD were identified among the HIV-positive and HIV-negative populations, respectively...
June 13, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28610590/a-continuous-quality-improvement-intervention-to-improve-the-effectiveness-of-community-health-workers-providing-care-to-mothers-and-children-a-cluster-randomised-controlled-trial-in-south-africa
#8
Christiane Horwood, Lisa Butler, Pierre Barker, Sifiso Phakathi, Lyn Haskins, Merridy Grant, Ntokozo Mntambo, Nigel Rollins
BACKGROUND: Community health workers (CHWs) play key roles in delivering health programmes in many countries worldwide. CHW programmes can improve coverage of maternal and child health services for the most disadvantaged and remote communities, leading to substantial benefits for mothers and children. However, there is limited evidence of effective mentoring and supervision approaches for CHWs. METHODS: This is a cluster randomised controlled trial to investigate the effectiveness of a continuous quality improvement (CQI) intervention amongst CHWs providing home-based education and support to pregnant women and mothers...
June 13, 2017: Human Resources for Health
https://www.readbyqxmd.com/read/28605171/human-immunodeficiency-virus-care-cascade-among-sub-populations-in-rakai-uganda-an-observational-study
#9
Veena G Billioux, Larry W Chang, Steven J Reynolds, Gertrude Nakigozi, Joseph Ssekasanvu, Mary K Grabowski, Robert Ssekubugu, Fred Nalugoda, Godfrey Kigozi, Joseph Kagaayi, David Serwadda, Ronald H Gray, Maria J Wawer
INTRODUCTION: To assess progress towards the UNAIDS 90-90-90 initiative targets, we examined the HIV care cascade in the population-based Rakai Community Cohort Study (RCCS) in rural Uganda and examined differences between sub-groups. METHODS: Self-reports and clinical records were used to assess the proportion achieving each stage in the cascade. Statistical inference based on a χ(2) test for categorical variables and modified Poisson regression were used to estimate prevalence risk ratios (PRRs) and 95% confidence intervals (CI) for enrolment into care and initiating antiretroviral therapy (ART)...
June 5, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28604435/exchange-sex-and-hiv-infection-among-women-who-inject-drugs-20-us-cities-2009
#10
Lina M Nerlander, Kristen L Hess, Charles E Rose, Catlainn Sionean, Anna Thorson, Dita Broz, Gabriela Paz-Bailey
BACKGROUND: Women who inject drugs and who also exchange sex are at increased risk for HIV infection, but data on this population in the United States remain sparse. METHODS: This study assessed the prevalence of exchanging sex for money or drugs among women who inject drugs using data from the 2009 US National HIV Behavioral Surveillance (NHBS) system. Prevalence of being HIV-positive (testing positive in NHBS), HIV-positive-unaware (reporting being HIV-negative or unknown status but testing positive in NHBS), and risk behaviors and use of services were compared between women who did and did not exchange sex...
July 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28604427/health-care-use-and-hiv-related-behaviors-of-black-and-latina-transgender-women-in-3-us-metropolitan-areas-results-from-the-transgender-hiv-behavioral-survey
#11
Damian J Denson, Paige M Padgett, Nicole Pitts, Gabriela Paz-Bailey, Trista Bingham, Juli-Ann Carlos, Pamela McCann, Nikhil Prachand, Jan Risser, Teresa Finlayson
PURPOSE: HIV prevalence estimates among transgender women in the United States are high, particularly among racial/ethnic minorities. Despite increased HIV risk and evidence of racial disparities in HIV prevalence among transgender women, few data are available to inform HIV prevention efforts. METHODS: A transgender HIV-related behavioral survey conducted in 2009 in 3 US metropolitan areas (Chicago, Houston, and Los Angeles County), used respondent-driven sampling to recruit 227 black (n = 139) and Latina (n = 88) transgender women...
July 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28604240/the-influence-of-social-constructs-of-hegemonic-masculinity-and-sexual-behaviour-on-acceptability-of-vaginal-microbicides-in-zambia
#12
Oliver Mweemba, Rachael Dixey, Virginia Bond, Alan White
Vaginal microbicides are heralded as a woman's HIV prevention method. This study, conducted in a microbicide clinical trial setting in Zambia, explored how the social construction of masculinity and sexual behaviour influenced the acceptability of vaginal microbicides. The data were generated from 18 In-depth Interviews and 8 Focus Group Discussions. The data were analysed thematically. The study found that hegemonic masculinity influenced the use of vaginal microbicides positively and negatively, in multiple ways including: decision to initiate gel use, autonomous use of the gel, and consistent use of the gel...
June 12, 2017: Global Public Health
https://www.readbyqxmd.com/read/28600490/treating-tobacco-dependence-guidance-for-primary-care-on-life-saving-interventions-position-statement-of-the-ipcrg
#13
O C P Van Schayck, S Williams, V Barchilon, N Baxter, M Jawad, P A Katsaounou, B J Kirenga, C Panaitescu, K W I G Tsiligianni, N Zwar, A Ostrem
Tobacco smoking is the world's leading cause of premature death and disability. Global targets to reduce premature deaths by 25% by 2025 will require a substantial increase in the number of smokers making a quit attempt, and a significant improvement in the success rates of those attempts in low, middle and high income countries. In many countries the only place where the majority of smokers can access support to quit is primary care. There is strong evidence of cost-effective interventions in primary care yet many opportunities to put these into practice are missed...
June 9, 2017: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/28600331/does-maternal-hsv-2-coinfection-increase-mother-to-child-transmission-of-hiv-a-systematic-review
#14
REVIEW
Vishalini Sivarajah, Kevin Venus, Mark H Yudin, Kellie E Murphy, Steven A Morrison, Darrell Hs Tan
BACKGROUND: Reducing HIV mother-to-child transmission (MTCT) is critical to ending the HIV pandemic. Reports suggest that herpes simplex virus-2 (HSV-2), a common coinfection in HIV-infected individuals, is associated with increased MTCT, but results have been conflicting. We conducted a systematic review of observational studies to quantify the magnitude of this relationship (PROSPERO no. CRD42016043315). METHODS: We searched Medline (1981 to June week 3, 2016), EMBASE (1981 to week 26, 2016), relevant conferences (2013-2016) and bibliographies of identified studies for cohort and case-control studies enrolling HIV-positive women during pregnancy or peripartum that quantified the effect of HSV-2 infection on MTCT...
June 9, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28595298/lowered-rilpivirine-exposure-during-third-trimester-of-pregnancy-in-hiv-1-positive-women
#15
Stein Schalkwijk, Angela Colbers, Deborah Konopnicki, Andrea Gingelmaier, John Lambert, Marchina van der Ende, José Moltó, David Burger
Background: The use of antiretroviral therapy during pregnancy is important for control of maternal HIV disease and the prevention of perinatal HIV transmission. Physiological changes during pregnancy can reduce antiretroviral exposure. We studied the pharmacokinetics of rilpivirine 25 mg once daily (QD) in HIV-1-positive women during late pregnancy. Methods: We conducted a non-randomized, open-label, multi-centre, phase-IV study. HIV-positive pregnant women receiving rilpivirine 25 mg QD were included...
June 8, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28593404/association-between-depressive-symptom-patterns-and-clinical-profiles-among-persons-living-with-hiv
#16
N E Kelso-Chichetto, C N Okafor, R L Cook, A G Abraham, R Bolan, M Plankey
To describe patterns of depressive symptoms across 10-years by HIV status and to determine the associations between depressive symptom patterns, HIV status, and clinical profiles of persons living with HIV from the Multicenter AIDS Cohort Study (N = 980) and Women's Interagency HIV Study (N = 1744). Group-based trajectory models were used to identify depressive symptoms patterns between 2004 and 2013. Multinomial logistic regressions were conducted to determine associations of depression risk patterns. A 3-group model emerged among HIV-negative women (low: 58%; moderate: 31%; severe: 11%); 5-groups emerged among HIV-positive women (low: 28%; moderate: 31%; high: 25%; decreased: 7%; severe: 9%)...
June 7, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28590237/evaluation-of-self-collected-rectal-swabs-for-the-detection-of-bacteria-responsible-for-sexually-transmitted-infections-in-a-cohort-of-hiv-1-infected-patients
#17
Sophie Edouard, Catherine Tamalet, Hervé Tissot-Dupont, Philippe Colson, Amélie Ménard, Isabelle Ravaux, Catherine Dhiver, Christelle Tomei, Andreas Stein, Didier Raoult
PURPOSE: The standard approach to screening sexually transmitted infections (STIs) has often been restricted to urogenital specimens. Most current guidelines, however, also recommend testing extra-genital sites, including rectal locations, because asymptomatic rectal carriage of pathogens has often been reported. The aim of our study was to evaluate self-collected rectal swabs to screen bacterial STIs in HIV-infected patients in Marseille, France. METHODOLOGY: Between January 2014 and December 2015, 118 HIV-infected patients (93 males and 25 females) agreed to self-sample anal swabs for detection of bacterial STI...
June 8, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28588953/trends-and-level-of-control-of-hypertension-among-adults-attending-an-ambulatory-hiv-clinic-in-kampala-uganda-a-retrospective-study
#18
Robert Kalyesubula, Alex Kayongo, Fred Collins Semitala, Asaph Muhanguzi, Nehemiah Katantazi, Dieter Ayers, Jamie I Forrest, Edward J Mills
BACKGROUND: With an ageing HIV-positive population, sub-Saharan Africa is now facing a dual epidemic of communicable and non-communicable diseases (NCDs). This study aimed to assess trends in the prevalence of hypertension and factors associated with hypertension, among adults attending an ambulatory HIV clinic in Kampala, Uganda. METHODS: We conducted a retrospective chart review to identify patients with hypertension. We used a random number generator to select 400 patient charts from each year from 2009 to 2014...
November 2016: BMJ Global Health
https://www.readbyqxmd.com/read/28583150/prevalence-of-pregnancy-relevant-infections-in-a-rural-setting-of-ghana
#19
Fabian Völker, Paul Cooper, Oliver Bader, Angela Uy, Ortrud Zimmermann, Raimond Lugert, Uwe Groß
BACKGROUND: Although infectious diseases still account for a high burden of morbidity and mortality in sub-Saharan Africa, simultaneous investigations on multiple infections affecting maternal and child health are missing. METHODS: We conducted a cross-sectional, single-centre pilot study in a rural area of Ghana to assess the infectiological profile during pregnancy. Screening of 180 expectant mothers was done by vaginal swabs and serology to detect the most common pregnancy-relevant infections...
June 6, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28583021/relationships-matter-contraceptive-choices-among-hiv-positive-women-in-tanzania
#20
Tabitha Alexandria Njeri Nyanja, Charlotte Tulinius
Efforts to eliminate mother-to-child transmission of HIV in Tanzania are guided by a four-prong strategy advocated by the World Health Organization (WHO). Prong 2, prevention of unintended pregnancies among women living with HIV, has, however, received the least attention and contraceptive use to prevent unintended pregnancies remains low. This study explored the perceived barriers to the use of modern methods of contraception, and factors influencing contraceptive choice among HIV-positive women in urban Dar-es-Salaam, Tanzania...
June 6, 2017: African Journal of AIDS Research: AJAR
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