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Phantom limb pain PLP

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https://www.readbyqxmd.com/read/27887967/percutaneous-image-guided-cryoablation-for-the-treatment-of-phantom-limb-pain-in-amputees-a-pilot-study
#1
J David Prologo, Charles A Gilliland, Michael Miller, Paul Harkey, Jackie Knight, Darren Kies, C Matthew Hawkins, David Corn, David K Monson, Faramarz Edalat, Sean Dariushnia, Luke Brewster
PURPOSE: To prospectively evaluate percutaneous image-guided nerve cryoablation for treatment of refractory phantom limb pain (PLP) in a pilot cohort for purposes of deriving parameters to design a larger, randomized, parallel-armed, controlled trial. MATERIALS AND METHODS: From January 2015 to January 2016, 21 patients with refractory PLP underwent image-guided percutaneous cryoneurolysis procedures. Visual analog scale scores were documented at baseline and 7, 45, and 180 days after the procedure...
November 22, 2016: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/27834472/diagnosis-and-treatment-of-pain-in-plexopathy-radiculopathy-peripheral-neuropathy-and-phantom-limb-pain-evidence-and-recommendations-from-the-italian-consensus-conference-on-pain-on-neurorehabilitation
#2
Francesco Ferraro, Marco Jacopetti, Vincenza Spallone, Luca Padua, Marco Traballesi, Stefano Brunelli, Cristina Cantarella, Cristina Ciotti, Daniele Coraci, Elena Dalla Toffola, Silvia Mandrini, Giovanni Morone, Costanza Pazzaglia, Marcello Romano, Angelo Schenone, Rossella Togni, Stefano Tamburin
Pain may affect all aspects of social life and reduce the quality of life. Neuropathic pain (NP) is common in patients affected by plexopathy, radiculopathy, mononeuropathy, peripheral neuropathy. Phantom limb pain (PLP) is a painful sensation that is common after amputation, and its pathophysiological mechanisms involve changes in the peripheral and central nervous system. Given the lack of conclusive evidence and specific guidelines on these topics, the aim of the Italian Consensus Conference on Pain on Neurorehabilitation (ICCPN) was to collect evidence and offer recommendations to answer currently open questions on the assessment and treatment of NP associated with the above conditions and PLP...
November 11, 2016: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27813692/memantine-for-the-treatment-of-phantom-limb-pain-a-systematic-review
#3
Brittany M Loy, Rachel B Britt, Jamie N Brown
Phantom limb pain (PLP) occurs in up to 85% of patients who have undergone an amputation and remains difficult to treat. Memantine is a N-Methyl-d-aspartate receptor antagonist that has shown benefit in pain syndromes. The objective of this systematic review is to evaluate the evidence for the use of memantine in the treatment of acute and chronic PLP. MEDLINE (1956 to May 2016) and Embase (1957 to May 2016) were queried for articles that characterized the clinical outcomes of patient(s) treated with memantine for PLP...
November 4, 2016: Journal of Pain & Palliative Care Pharmacotherapy
https://www.readbyqxmd.com/read/27813030/the-effect-of-mirror-therapy-on-the-management-of-phantom-limb-pain
#4
Meltem Yıldırım, Nevin Kanan
OBJECTIVES: In the last two decades, mirror therapy has become a frequently used method of managing phantom limb pain (PLP). However, the role of nurses in mirror therapy has not yet been well defined. This study examined the effect of mirror therapy on the management of PLP, and discusses the importance of mirror therapy in the nursing care of amputee patients. METHODS: This quasi-experimental study was conducted in the pain management department of a university hospital and a prosthesis clinic in İstanbul, Turkey, with 15 amputee patients who had PLP...
July 2016: Aǧrı: Ağrı (Algoloji) Derneği'nin Yayın Organıdır, the Journal of the Turkish Society of Algology
https://www.readbyqxmd.com/read/27782861/acupuncture-for-the-treatment-of-phantom-limb-syndrome-in-lower-limb-amputees-a-randomised-controlled-feasibility-study
#5
Esmé G Trevelyan, Warren A Turner, Lynn Summerfield-Mann, Nicola Robinson
BACKGROUND: Post amputation, the complication of phantom limb pain (PLP) is prevalent and difficult to manage. This study aimed to determine whether it was feasible and acceptable to undertake a definitive multicentred randomised controlled trial assessing the effectiveness of acupuncture for treating lower limb amputees with PLP. METHODS: A mixed-methods embedded design, including a randomised controlled trial and semistructured interviews, was undertaken. A total of 15 participants with PLP were randomly assigned to receive either eight pragmatic Traditional Chinese Medicine acupuncture treatments and usual care or usual care alone over 4 weeks...
October 25, 2016: Trials
https://www.readbyqxmd.com/read/27780402/a-systematic-review-on-the-treatment-of-phantom-limb-pain-with-spinal-cord-stimulation
#6
Rohit Aiyer, Robert L Barkin, Anurag Bhatia, Semih Gungor
: Phantom limb pain (PLP) is a challenging chronic pain syndrome to treat with pharmacologic agents being first line of management. However, when these agents fail to provide pain relief, other interventions must be considered in a clinical setting. Spinal cord stimulation (SCS) has been shown to provide analgesia in PLP, and should be considered by clinicians. METHODS: This PRISMA systematic review analyzes the efficacy of SCS for treatment of PLP. RESULTS: After review of 12 studies, there are mixed results to base a conclusion on...
January 2017: Pain Management
https://www.readbyqxmd.com/read/27737513/pharmacologic-interventions-for-treating-phantom-limb-pain
#7
REVIEW
Maria Jenelyn M Alviar, Tom Hale, Monalisa Dungca
BACKGROUND: This is an updated version of the original Cochrane review published in Issue 12, 2011. Phantom limb pain (PLP) is pain that arises in the missing limb after amputation and can be severe, intractable, and disabling. Various medications have been studied in the treatment of phantom pain. There is currently uncertainty in the optimal pharmacologic management of PLP. OBJECTIVES: This review aimed to summarise the evidence of effectiveness of pharmacologic interventions in treating PLP...
October 14, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27676814/the-effects-of-mirror-therapy-on-pain-and-motor-control-of-phantom-limb-in-amputees-a-systematic-review
#8
Jessie Barbin, Vanessa Seetha, Jean-Marie Casillas, Jean Paysant, Dominic Perennou
OBJECTIVE: Phantom limb pain (PLP) is a major problem after limb amputation. Mirror therapy (MT) is a non-pharmacological treatment using representations of movement, the efficacy of which in reducing PLP remains to be clarified. Here, we present the first systematic review on MT efficacy in phantom limb pain (PLP) and phantom limb movement (PLM) in amputees (lower or upper limb). MATERIAL/PATIENTS AND METHODS: A search on MEDLINE, COCHRANE DATABASE and EMBASE, crossing the key words "phantom limb" and "mirror therapy" found studies which were read and analyzed according the PRISMA statement...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27582042/the-effects-of-graded-motor-imagery-and-its-components-on-phantom-limb-pain-and-disability-in-upper-and-lower-limb-amputees-a-systematic-review-protocol
#9
Katleho Limakatso, Lieselotte Corten, Romy Parker
BACKGROUND: Phantom limb pain (PLP) is characterized by the anatomical shifting of neighbouring somatosensory and motor areas into a deafferented cortical area of the brain contralateral to the amputated limb. It has been shown that maladaptive neuroplasticity is positively correlated to the perception of PLP in amputees. Recent studies support the use of graded motor imagery (GMI) and its component to alleviate the severity of PLP and disability. However, there is insufficient collective empirical evidence exploring the effectiveness of these treatment modalities in amputees with PLP...
2016: Systematic Reviews
https://www.readbyqxmd.com/read/27551416/perceptions-of-phantom-limb-pain-in-lower-limb-amputees-and-its-effect-on-quality-of-life-a-qualitative-study
#10
Esmé G Trevelyan, Warren A Turner, Nicola Robinson
BACKGROUND: Phantom limb pain (PLP) is a prevalent complication post-amputation. Currently, qualitative literature exploring the experience of PLP in amputees is sparse, and little is known about whether the educational needs of amputees are being met. OBJECTIVES: To explore lower limb amputees' descriptive lived experiences of PLP, to understand how PLP affects quality of life and to determine whether amputees feel they are provided with adequate information about PLP...
May 2016: British Journal of Pain
https://www.readbyqxmd.com/read/27383993/optimizing-rehabilitation-for-phantom-limb-pain-using-mirror-therapy-and-transcranial-direct-current-stimulation-a-randomized-double-blind-clinical-trial-study-protocol
#11
Camila Bonin Pinto, Faddi Ghassan Saleh Velez, Nadia Bolognini, David Crandell, Lotfi B Merabet, Felipe Fregni
BACKGROUND: Despite the multiple available pharmacological and behavioral therapies for the management of chronic phantom limb pain (PLP) in lower limb amputees, treatment for this condition is still a major challenge and the results are mixed. Given that PLP is associated with maladaptive brain plasticity, interventions that promote cortical reorganization such as non-invasive brain stimulation and behavioral methods including transcranial direct current stimulation (tDCS) and mirror therapy (MT), respectively, may prove to be beneficial to control pain in PLP...
2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27378656/restoring-movement-representation-and-alleviating-phantom-limb-pain-through-short-term-neurorehabilitation-with-a-virtual-reality-system
#12
M Osumi, A Ichinose, M Sumitani, N Wake, Y Sano, A Yozu, S Kumagaya, Y Kuniyoshi, S Morioka
BACKGROUND AND OBJECTIVE: We developed a quantitative method to measure movement representations of a phantom upper limb using a bimanual circle-line coordination task (BCT). We investigated whether short-term neurorehabilitation with a virtual reality (VR) system would restore voluntary movement representations and alleviate phantom limb pain (PLP). METHODS: Eight PLP patients were enrolled. In the BCT, they repeatedly drew vertical lines using the intact hand and intended to draw circles using the phantom limb...
July 5, 2016: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/27375755/phantom-limb-sensation-pls-and-phantom-limb-pain-plp-among-young-landmine-amputees
#13
Mahtab Poor Zamany Nejatkermany, Ehsan Modirian, Mohammadreza Soroush, Mehdi Masoumi, Maryam Hosseini
OBJECTIVE: To determine the frequency of phantom limb sensation (PLS) and phantom limb pain (PLP) in children and young adults suffering landmine-related amputation. MATERIALS & METHODS: All youths with amputation due to landmine explosions participated in this study. The proportions of patients with phantom limb sensation/pain, intensity and frequency of pain were reported. Chi square test was used to examine the relationship between variables. Comparison of PLP and PLS between upper and lower amputation was done by unpaired t-test...
2016: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/27260638/repetitive-transcranial-magnetic-stimulation-for-phantom-limb-pain-in-land-mine-victims-a-double-blinded-randomized-sham-controlled-trial
#14
Alejandra Malavera, Federico Arturo Silva, Felipe Fregni, Sandra Carrillo, Ronald G Garcia
UNLABELLED: We evaluated the effects of repetitive transcranial magnetic stimulation (rTMS) in the treatment of phantom limb pain (PLP) in land mine victims. Fifty-four patients with PLP were enrolled in a randomized, double-blinded, placebo-controlled, parallel group single-center trial. The intervention consisted of real or sham rTMS of M1 contralateral to the amputated leg. rTMS was given in series of 20 trains of 6-second duration (54-second intertrain, intensity 90% of motor threshold) at a stimulation rate of 10 Hz (1,200 pulses), 20 minutes per day, during 10 days...
August 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/27256539/the-effects-of-mirror-therapy-on-pain-and-motor-control-of-phantom-limb-in-amputees-a-systematic-review
#15
REVIEW
J Barbin, V Seetha, J M Casillas, J Paysant, D Pérennou
BACKGROUND AND OBJECTIVE: Phantom limb pain (PLP) is a major problem after limb amputation. Mirror therapy (MT) is a non-pharmacological treatment using representations of movement, the efficacy of which in reducing PLP remains to be clarified. Here, we present the first systematic review on MT efficacy in PLP and phantom limb movement (PLM) in amputees (lower or upper limb). METHODS: A search on Medline, Cochrane Database and Embase, crossing the keywords "Phantom Limb" and "Mirror Therapy" found studies which were read and analyzed according the PRISMA statement...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/26904856/-the-research-advances-of-the-pathomechanism-of-phantom-limb-pain-plp
#16
Qing-Qing Jin, Dan-Dan Tang, Wei-Wei Peng, Li Hu
Phantom limb pain (PLP) is a hallucination that the patient feels the existence off the limb after its loss and experiences somewhat pain of the missing limb. Such a pain normally appears in the distal end of the missing limb. Currently, the pathomechanism of PLP is still unclear, and the clinical research of PLP mainly relies on the subjective report of the patients and the psychophysical measurements. In this paper, we discuss extensively the pathomechanism of PLP, and summarize comprehensively the advanced methods for studying the pathomechanism of PLP...
October 2015: Sheng Li Ke Xue Jin Zhan [Progress in Physiology]
https://www.readbyqxmd.com/read/26812182/residual-limb-hyperhidrosis-and-rimabotulinumtoxinb-a-randomized-placebo-controlled-study
#17
Paul F Pasquina, Briana N Perry, Aimee L Alphonso, Sacha Finn, Kevin F Fitzpatrick, Jack W Tsao
OBJECTIVE: To investigate the use of rimabotulinumtoxinB (BoNT/B [Myobloc]) compared with placebo in treating hyperhidrosis in the residual limbs of individuals with amputation. DESIGN: Randomized, double-blind, placebo-controlled pilot study. SETTING: Military medical center. PARTICIPANTS: Male participants (N=9) with 11 major amputations of the lower limbs and who complained of excessive sweating in their residual limbs were enrolled in the study between September 24, 2008 to October 28, 2011...
May 2016: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/26802307/spinal-cord-stimulation-therapy-for-the-treatment-of-concomitant-phantom-limb-pain-and-critical-limb-ischemia
#18
Giovanni De Caridi, Mafalda Massara, Raffaele Serra, Claudia Risitano, Massimiliano Giardina, Ignazio Eduardo Acri, Pietro Volpe, Antonio David
Phantom limb pain (PLP) is a chronic condition experienced by about 80% of patients who have undergone amputation. In most patients, both the frequency and the intensity of pain attacks diminish with time, but severe pain persists in about 5-10%. Probably, factors in both the peripheral and central nervous system play a role in the occurrence and persistence of pain in the amputated lower limb. The classical treatment of PLP can be divided into pharmacologic, surgical, anesthetic, and psychological modalities...
April 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/26361601/successful-treatment-of-phantom-limb-pain-by-1-hz-repetitive-transcranial-magnetic-stimulation-over-affected-supplementary-motor-complex-a-case-report
#19
Jong-Hoo Lee, Jeong-Hyun Byun, Yu-Ri Choe, Seung-Kyu Lim, Ka-Young Lee, In-Sung Choi
A 37-year-old man with a right transfemoral amputation suffered from severe phantom limb pain (PLP). After targeting the affected supplementary motor complex (SMC) or primary motor cortex (PMC) using a neuro-navigation system with 800 stimuli of 1 Hz repetitive transcranial magnetic stimulation (rTMS) at 85% of resting motor threshold, the 1 Hz rTMS over SMC dramatically reduced his visual analog scale (VAS) of PLP from 7 to 0. However, the 1 Hz rTMS over PMC failed to reduce pain. To our knowledge, this is the first case report of a successfully treated severe PLP with a low frequency rTMS over SMC in affected hemisphere...
August 2015: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/26295728/telepain-management-of-phantom-limb-pain-using-mirror-therapy
#20
Ariana Gover-Chamlou, Jack W Tsao
BACKGROUND: In response to rising healthcare costs and the social and economic burden of outpatient rehabilitation services, telepain management has emerged as an exciting alternative method of clinical care. Patients with limb amputations who experience phantom limb pain (PLP) are typically treated unsuccessfully using medications, injections, or additional surgeries. Mirror therapy is a noninvasive, cost-effective alternative to current treatment options for PLP. PATIENTS AND METHODS: We report 2 patients who self-administered mirror therapy at home after receiving detailed instructions from a physician by e-mail...
August 21, 2015: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
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