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https://www.readbyqxmd.com/read/28904636/the-orthopaedic-management-of-lower-limb-deformity-in-hypophosphataemic-rickets
#1
A Horn, J Wright, D Bockenhauer, W Van't Hoff, D M Eastwood
BACKGROUND: Many patients with X-linked hypophosphataemic rickets (X-LHPR) demonstrate significant lower limb deformity despite optimal medical management. This study evaluates the use of guided growth by means of hemi-epiphysiodesis to address coronal plane deformity in the skeletally immature child. METHODS: Since 2005, 24 patients with X-LHPR have been referred to our orthopaedic unit for evaluation. All patients had standardised long leg radiographs that were analysed sequentially before and after surgery if any was performed...
August 1, 2017: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/28865049/exercise-therapy-for-treatment-of-supraspinatus-tears-does-not-alter-glenohumeral-kinematics-during-internal-external-rotation-with-the-arm-at-the-side
#2
Gerald A Ferrer, R Matthew Miller, Jason P Zlotnicki, Scott Tashman, James J Irrgang, Volker Musahl, Richard E Debski
PURPOSE: Rotator cuff tears are a significant clinical problem, with exercise therapy being a common treatment option for patients. Failure rates of exercise therapy may be due to the failure to improve glenohumeral kinematics. Tears involving the supraspinatus may result in altered glenohumeral kinematics and joint instability for internal/external rotation with the arm at the side because not all muscles used to stabilize the glenohumeral joint are functioning normally. The objective of the study is to assess in vivo glenohumeral kinematic changes for internal/external rotation motions with the arm at the side of patients with a symptomatic full-thickness supraspinatus tear before and after a 12-week exercise therapy programme...
September 1, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28844582/outcomes-of-isolated-radial-osteotomy-for-volar-distal-radioulnar-joint-instability-following-radial-malunion-in-children
#3
Ashley Miller, Nina Lightdale-Miric, Emily Eismann, Preston Carr, Kevin James Little
PURPOSE: The radius bone has a slight dorsoradial bow that allows for full forearm pronosupination around the ulna. However, radial malunion can lead to reversal of the radial bow and subsequent volar instability of the distal radioulnar joint (DRUJ), predominantly in supination. This study assessed the outcomes of corrective radial osteotomy for volar DRUJ instability after radial malunion in children. METHODS: The charts of 7 children (2 boys and 5 girls) treated with corrective radial osteotomy for volar DRUJ instability after a radius fracture or deformity were reviewed...
August 23, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28844198/medial-external-fixation-for-staged-treatment-of-closed-calcaneus-fractures-surgical-technique-and-case-series
#4
Michael Githens, Joshua Shatsky, Julie Agel, Richard J Bransford, Stephen K Benirschke
The derangement in calcaneal morphology after a fracture can be significant and is often associated with severe soft tissue envelop problems. Medial calcaneal external fixation is useful for early restoration of calcaneal morphology and the corresponding soft tissue envelop. When performed in a stepwise fashion, external fixation can successfully restore normal calcaneal height, length, width, and coronal plane alignment. For severely displaced joint depression and broken tongue-type calcaneus fractures where open treatment is the preferred strategy, early external fixation restores the normal soft tissue tension, allows a stable environment for soft tissue recovery, and facilitates the definitive operation by restoring and maintaining overall calcaneal architecture...
September 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28842365/spinal-deformity-changes-in-children-with-long-term-vertical-expandable-prosthetic-titanium-rib-veptr-treatment
#5
Andrea S Gantner, Lena Braunschweig, Konstantinos Tsaknakis, Heiko M Lorenz, Anna K Hell
BACKGROUND CONTEXT: In several studies, vertical expandable prosthetic titanium rib (VEPTR) implants have shown good scoliosis control in children with the longest reported follow-up (f/u) of 3.6 years. For growing rods, recent studies suggest a decreased efficiency of correction starting just after that time. To our knowledge, no long-term results of children with VEPTR treatment are available. PURPOSE: To evaluate spinal deformity in scoliotic children and to investigate correction potential of VEPTR implants at several time points of treatment, particularly after long-term f/u...
August 22, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28753160/-fat-grafting-in-the-hollow-upper-eyelids-and-volumetric-upper-blepharoplasty
#6
Mariano E Ramil
BACKGROUND: Periorbital volume loss creates a shadow frame, where traditional excisional blepharoplasties may aggravate the situation. Divergence in filling treatments establishes a demand for simple and reproducible techniques to achieve consistent results. Here, the author's hollow upper eyelid evaluation and treatment approach are presented. METHODS: A retrospective photographic analysis was conducted for 32 women who underwent fat grafting on the hollow upper eyelids between 2012 and 2016...
July 27, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28727466/ceramic-veneers-with-gingiva-shaded-porcelain-to-replace-lost-interdental-papillae-a-case-report
#7
Stephen J Chu, Adam J Mieleszko
With implant-supported reconstructions, gingiva-shaded pink-colored restorative materials serve as an option for replacing both hard and soft tissues cosmetically. This article presents a case report describing restorative treatment for a patient who requested individual crowns and veneers after she had had multiple surgical interventions to replace a failing implant tooth No. 9. In addition to replacement of the implant prosthesis, this case involved restorative papillae reconstruction that was performed to treat interdental recession that had occurred after the surgeries...
July 2017: Compendium of Continuing Education in Dentistry
https://www.readbyqxmd.com/read/28697086/use-of-volar-plate-for-indirect-coronal-plane-reduction-in-an-intraarticular-distal-radius-fracture
#8
Rebecca Senehi, Tyani D Luo, Alejandro Marquez-Lara, Arun Aneja, Hoyt R Beard, Eben A Carroll
Management of intraarticular distal radius fractures requires precise reconstruction of the articular surface to optimize outcomes. Treatment goals also include restoration of alignment, rotation, and angulation in both the coronal and sagittal planes of the metaphyseal component of these fractures. Surgical management with open reduction and internal fixation with a volar plate is often the preferred method of open treatment. However, a variety of different techniques have been described, and the preferred technique may be determined on an individual basis by the fracture characteristics, patient-dependent factors, or surgeon experience...
August 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28692925/role-of-the-adjunctive-antimicrobial-photodynamic-therapy-to-periodontal-treatment-at-plasmatic-oxidative-stress-and-vascular-behavior
#9
L M Barin, R C S Barcelos, L T Vey, F M Pillusky, V M Palma, K Z Kantorski, M E Bürger, R M Maciel, C C Danesi
BACKGROUND: To evaluate for the first time in vivo the effects of methylene blue (MB) photosensitizer dissolved in ethanol in antimicrobial photodynamic therapy (aPDT) as adjuvant periodontal treatment, at plasmatic oxidative stress and vascular behavior in rat model. METHODS: Wistar rats were divided into negative control (NC, no periodontitis) and positive control (PC, with periodontitis, without any treatment). The other groups had periodontitis and were treated with scaling and root planing (SRP); SRP+aPDT+MB dissolved in water (aPDT I); SRP+aPDT+MB dissolved in ethanol (aPDT II)...
June 28, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28621288/photodvnamic-therapy-in-endodontics
#10
Zahed Mohammadi, Hamid Jafarzadeh, Sousan Shalavi, Jun-Ichiro Kinoshita
Commonly used irrigants do not always eradicate the entire microbial flora in infected root canals. Therefore, several other strategies, such as photodynamic therapy (PDT) have been developed. Photoactivated disinfection is based on the interaction of a photosensitive antibacterial agent and a light source. It uses a nontoxic dye named photosensitizer (PS) and low-intensity visible light. In oxygen presentation, these combine to produce some cytotoxic species. The PS molecules attach to bacteria membrane. Irradiation with a specific wavelength of the light may lead to the production of singlet oxygen, resulting in rupture of the microbial cell wall...
June 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28587977/combination-of-straight-and-tilted-implants-for-supporting-screw-retained-dental-prostheses-in-atrophic-posterior-maxillae-a-2-year-prospective-study
#11
Juan-Carlos Casar-Espinosa, Raquel Castillo-Oyagüe, María Ángeles Serrera-Figallo, Roberto Garrido-Serrano, Christopher D Lynch, Manuel Menéndez-Collar, Daniel Torres-Lagares, José-Luis Gutiérrez-Pérez
OBJECTIVES: To evaluate the two-year survival rate (SR) and marginal bone loss (MBL) of fixed dental prostheses (FDPs) supported by straight (S) and tilted (T) implants under the influence of diverse study variables. METHODS: A prospective investigation comprising 21 patients provided with a total of 27 maxillary screw-retained restorations fixed to 70 dental implants was developed. Two groups of implants were considered depending on their inclination with respect to the occlusal plane: Group 1 (S, n=37): straight/axial implants and Group 2 (T, n=33): tilted/angled fixations...
June 3, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28507175/a-mutation-in-the-bhlh-domain-of-the-spch-transcription-factor-uncovers-a-br-dependent-mechanism-for-stomatal-development
#12
Alberto de Marcos, Anaxi Houbaert, Magdalena Triviño, Dolores Delgado, Mar Martín-Trillo, Eugenia Russinova, Carmen Fenoll, Montaña Mena
The asymmetric cell divisions necessary for stomatal lineage initiation and progression in Arabidopsis (Arabidopsis thaliana) require the function of the basic helix-loop-helix (bHLH) transcription factor SPEECHLESS (SPCH). Mutants lacking SPCH do not produce stomata or lineages. Here, we isolated a new spch-5 allele carrying a point mutation in the bHLH domain that displayed normal growth, but had an extremely low number of sometimes clustered stomata in the leaves, whereas the hypocotyls did not have any stomata...
June 2017: Plant Physiology
https://www.readbyqxmd.com/read/28506773/antimicrobial-photodynamic-therapy-with-photosensitizer-in-ethanol-improves-oxidative-status-and-gingival-collagen-in-a-short-term-in-periodontitis
#13
Fernanda Maia Pillusky, Raquel Cristine Silva Barcelos, Luciana Taschetto Vey, Luisa Machado Barin, Victor de Mello Palma, Roberto Marinho Maciel, Karla Zanini Kantorski, Marilise Escobar Bürger, Cristiane Cademartori Danesi
BACKGROUND: This study evaluated the antimicrobial photodynamic therapy (aPDT) effects using the methylene blue (MB) in ethanol 20% on systemic oxidative status and collagen content from gingiva of rats with periodontitis. METHODS: Rats were divided into five experimental groups: NC (negative control; no periodontitis); PC (positive control; periodontitis without any treatment); SRP (periodontitis and scaling and root planing), aPDT I (periodontitis and SRP+aPDT+MB solubilized in water), and aPDT II (periodontitis and SRP+aPDT+MB solubilized in ethanol 20%)...
September 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28450925/therapeutic-effect-of-apocynin-through-antioxidant-activity-and-suppression-of-apoptosis-and-inflammation-after-spinal-cord-injury
#14
Yijun Sun, Futai Gong, Jichao Yin, Xiaoyan Wang, Xiangyang Wang, Qing Sun, Zhiqiang Zhu, Xiaoqiang Su, Jie Zheng, Li Liu, Yang Li, Xinglv Hu, Jia Li
Spinal cord injury (SCI) is a devastating condition affecting hundreds of thousands of people worldwide annually. SCI results in activation of the inflammatory response and apoptosis, and generates oxidative stress, which has deleterious effects on the recovery of motor function. Apocynin, an inhibitor of NADPH oxidase, has been demonstrated to improve neuronal functional recovery in rat models of SCI. However, the efficacy of apocynin treatment post-SCI has not been investigated. The aim of this study was to observe the effects of apocynin on the repair of acute spinal cord damage in rats and to examine the potential beneficial effects...
March 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28428911/early-rehabilitation-of-distal-radius-fractures-stabilized-by-volar-locking-plate-a-prospective-randomized-pilot-study
#15
Stefan Quadlbauer, Christoph Pezzei, Josef Jurkowitsch, Brigitta Kolmayr, Tina Keuchel, Daniel Simon, Thomas Hausner, Martin Leixnering
Background Distal radius fractures are very common and an increased incidence of 50% is estimated by 2030. Therefore, both operative and postsurgical treatment remains pertinent. Main aim in treating intra-articular fractures is to restore the articular surface by internal fixation and early mobilization (EM). Questions/Purposes The purpose of this study was to compare functional results between EM immediately after surgery and 5 weeks of immobilization (IM). Patients and Methods In a randomized prospective study, 30 patients with an isolated distal radius fracture were treated by open reduction and internal fixation using a single volar locking plate excluding bone graft...
May 2017: Journal of Wrist Surgery
https://www.readbyqxmd.com/read/28395943/computer-assisted-planning-and-patient-specific-guides-for-the-treatment-of-midshaft-clavicle-malunions
#16
Lazaros Vlachopoulos, Andreas Schweizer, Dominik C Meyer, Christian Gerber, Philipp Fürnstahl
BACKGROUND: The surgical treatment of malunions after midshaft clavicle fractures is associated with a number of potential complications and the surgical procedure is challenging. However, with appropriate and meticulous preoperative surgical planning, the surgical correction yields satisfactory results. The purpose of this study was to provide a guideline and detailed overview for the computer-assisted planning and 3-dimensional (3D) correction of malunions of the clavicle. METHODS: The 3D bone surface models of the pathologic and contralateral sides were created on the basis of computed tomography data...
August 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28394871/triplanar-humeral-osteotomy-for-restoration-of-midline-function-in-patients-with-brachial-plexus-birth-palsy
#17
John D Jennings, Dustin A Greenhill, Scott H Kozin, Dan A Zlotolow
Brachial plexus birth palsy resolves spontaneously in a majority of patients, however, others may have serious permanent dysfunction. Although nerve transfers or grafts are early options for treatment, many children have residual deficits or present too late for such procedures. In these patients, rotational osteotomy of the humerus may restore improved function and motion. Unfortunately, traditional humeral osteotomies only provide correction in a single plane, therefore appropriate correction of the typical residual deformity is incomplete...
June 2017: Techniques in Hand & Upper Extremity Surgery
https://www.readbyqxmd.com/read/28224442/report-of-the-primary-outcomes-for-gait-mechanics-in-men-of-the-acl-sports-trial-secondary-prevention-with-and-without-perturbation-training-does-not-restore-gait-symmetry-in-men-1-or-2-years-after-acl-reconstruction
#18
Jacob John Capin, Ryan Zarzycki, Amelia Arundale, Kathleen Cummer, Lynn Snyder-Mackler
BACKGROUND: Movement asymmetries during walking are common after anterior cruciate ligament (ACL) injury and reconstruction and may influence the early development of posttraumatic osteoarthritis. Preoperative neuromuscular training (like perturbation training, which is neuromuscular training requiring selective muscle activation in response to surface perturbations) improves gait asymmetries and functional outcomes among people who are ACL-deficient, but the effect of postoperative perturbation training on gait mechanics after ACL reconstruction is unknown...
February 21, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28058731/improved-intercostal-hifu-ablation-using-a-phased-array-transducer-based-on-fermat-s-spiral-and-voronoi-tessellation-a-numerical-evaluation
#19
Pascal Ramaekers, Mario Ries, Chrit T W Moonen, Martijn de Greef
PURPOSE: A major complication for abdominal High Intensity Focused Ultrasound (HIFU) applications is the obstruction of the acoustic beam path by the thoracic cage, which absorbs and reflects the ultrasonic energy leading to undesired overheating of healthy tissues in the pre-focal area. Prior work has investigated the determination of optimized transducer apodization laws, which allow for a reduced rib exposure whilst (partially) restoring focal point intensity through power compensation...
March 2017: Medical Physics
https://www.readbyqxmd.com/read/28025026/hyperdynamic-right-heart-function-in-graves-hyperthyroidism-measured-by-echocardiography-normalises-on-restoration-of-euthyroidism
#20
Stephanie L Teasdale, Warrick J Inder, Michael Stowasser, Tony Stanton
BACKGROUND: Graves' hyperthyroidism commonly causes tachycardia and may result in pulmonary hypertension and high output cardiac failure. There is limited information regarding the effect of treatment on cardiac function measured using modern echocardiographic techniques. METHODS: Eight individuals with Graves' hyperthyroidism, aged 22-64 years, underwent comprehensive transthoracic echocardiography at three time points: before treatment, two weeks after commencement of carbimazole, and at six months or more when euthyroid...
November 19, 2016: Heart, Lung & Circulation
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