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https://www.readbyqxmd.com/read/29912226/-make-a-point-on-left-ventricular-noncompaction
#1
Francesco Negri, Antonio De Luca, Gaetano Morea, Matteo Dal Ferro, Giorgio Faganello, Giancarlo Vitrella, Mario Chiatto, Bruno Pinamonti, Giovanni Donato Aquaro, Gianfranco Sinagra
Hypertrabeculation is a feature of the left ventricle that, by itself, does not coincide with left ventricular non compaction (LVNC), which represents a specific cardiomyopathy. Nowadays, in the absence of gold standard diagnostic criteria, the clinician must integrate imaging aspects together with medical history. The family inheritance for LVNC, presence of neuromuscular disorders, symptoms or signs of heart failure, thromboembolic events, unexplained syncope, pathological findings at rest ECG, Holter ECG, stress test, systolic/diastolic dysfunction at rest echocardiogram, late gadolinium enhancement at cardiac magnetic resonance, and identification of specific mutations are all considered features useful for the diagnosis...
June 2018: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/29912225/-when-and-how-to-investigate-myocardial-viability-in-clinical-practice
#2
Elena Giulia Milano, Tobias Andreas Fuchs, Alice Niero, Estefania De Garate, Anna Baritussio, Chiara Bucciarelli-Ducci
The assessment of myocardial viability is a crucial step in the work-up of patients with coronary artery disease and left ventricular (LV) systolic dysfunction. Myocardial revascularization should be considered in patients with viable myocardium and LV systolic dysfunction, since this could improve LV function and outcomes.Noninvasive imaging plays a key role in the study of viability and different modalities are currently available, including cardiac magnetic resonance, stress echocardiography and nuclear imaging...
June 2018: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/29912207/improved-registration-of-3d-ct-angiography-with-x-ray-fluoroscopy-for-image-fusion-during-transcatheter-aortic-valve-implantation
#3
Ina Vernikouskaya, Wolfgang Rottbauer, Julia Seeger, Birgid Gonska, Jochen Wöhrle, Volker Rasche
The fusion of 3D anatomical models derived from high-fidelity pre-interventional computed tomography angiography (CTA), and x-ray (XR) fluoroscopy to facilitate anatomical guidance is of huge interest for complex cardiac interventions like TAVI procedures with cerebral protection. Co-registration of CTA and XR has been introduced either based on additional intraoperative non-/contrast-enhanced cone-beam computed tomography (CBCT) or two separate aortograms. With the related increase of radiation exposure and/or contrast agent (CA) dose, a potential additional risk for the patient is introduced...
June 3, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29912202/suppression-of-pro-fibrotic-signaling-potentiates-factor-mediated-reprogramming-of-mouse-embryonic-fibroblasts-into-induced-cardiomyocytes
#4
Andrew S Riching, Yuanbiao Zhao, Yingqiong Cao, Pilar Londono, Hongyan Xu, Kunhua Song
Trans-differentiation of one somatic cell type into another has enormous potential to model and treat human diseases. Previous studies have shown that mouse embryonic, dermal, and cardiac fibroblasts can be reprogrammed into functional induced-cardiomyocyte-like cells (iCMs) through overexpression of cardiogenic transcription factors including GATA4, Hand2, Mef2c, and Tbx5 both in vitro and in vivo. However, these previous studies have shown relatively low efficiency. In order to restore heart function following injury, mechanisms governing cardiac reprogramming must be elucidated to increase efficiency and maturation of iCMs...
June 3, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29912019/left-atrial-strain-measurement-and-clinical-application
#5
Jonathan Buggey, Brian D Hoit
PURPOSE OF REVIEW: To summarize recent literature on the use of left atrial strain in the diagnosis and management of patients with heart failure. RECENT FINDINGS: Left atrial dysfunction is a hallmark of diastolic dysfunction and heart failure, in particular, heart failure with preserved ejection fraction (HFpEF). Recently, myocardial deformation analysis via strain and strain rate measurements have been applied to the left atrium. These measurements have been shown to aid in the diagnosis of heart failure and be accurate predictors of cardiac pressures, diastolic dysfunction, exercise performance, and clinical outcomes such as cardiac hospitalizations and mortality...
June 14, 2018: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/29911765/computed-tomography-image-of-a-mediastinal-mass-producing-cardiac-tamponade
#6
Adi Guy, Corey Saperia, Mohammed S Yassin, Howard Amital
No abstract text is available yet for this article.
June 2018: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29911451/effect-of-well-controlled-gestational-diabetes-on-left-ventricular-diastolic-dysfunction-in-neonates
#7
Yazdan Ghandi, Danial Habibi, Khadijeh Nasri, Saeed Alinejad, Hassan Taherahmad, Ali Arjmand Shabestari, Ali Nematinejad
BACKGROUND: There are some evidences supporting the relation between gestational diabetes mellitus (GDM) and diastolic dysfunction. The aim of our study was to investigate the effect of well-controlled GDM on morphological and functional myocardium. MATERIALS AND METHODS: We designed a prospective cross-sectional study to evaluate left ventricular (LV) diastolic function of 60 neonates born from mothers with well-controlled GDM (case group) on days of 3-5 after birth...
June 17, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29911392/remote-ischaemic-conditioning-for-myocardial-infarction-or-elective-pci-systematic-review-and-meta-analyses-of-randomised-trials
#8
Paul M Haller, Kris G Vargas, Maria C Haller, Edita Piackova, Johann Wojta, Mariann Gyöngyösi, Bernard J Gersh, Attila Kiss, Bruno K Podesser, Kurt Huber
BACKGROUND: The efficacy of remote ischaemic conditioning in clinical trials of ST-segment elevation myocardial infarction (STEMI) or elective percutaneous coronary intervention is controversial. We aimed to systematically review and meta-analyse whether remote ischaemic conditioning reduces myocardial damage in those patients. METHODS: We searched PubMed, Embase and Web of Science from inception until December 2017 for randomised clinical trials evaluating remote ischaemic conditioning versus a control group...
June 1, 2018: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29910585/a-huge-morgagni-hernia-with-compression-of-the-right-ventricle
#9
Paolo Ciancarella, Fabio Fazzari, Valentina Montano, Marco Guglielmo, Gianluca Pontone
A 21 year old male with no relevant medical history presented to our Institution for further assessments of a right paracardiac mass founded on a chest X-ray. Chest computed tomography revealed a wide median defect of the diaphragm at the level of xiphoid process of the sternum, with the herniation of omental fat tissue in the mediastinum. Cardiac magnetic resonance confirmed the presence of a huge hernia originating from the foramen of Morgagni (sterno-costal hiatus), displacing the heart leftwards and posteriorly and compressing the right ventricle (RV), giving to it a tubular shape...
April 2018: Journal of the Saudi Heart Association
https://www.readbyqxmd.com/read/29910577/status-of-f-18-fluorodeoxyglucose-uptake-in-normal-and-hibernating-myocardium-after-glucose-and-insulin-loading
#10
Ismet Sarikaya, A H Elgazzar, M A Alfeeli, P N Sharma, A Sarikaya
Objective: F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) has been increasingly used in myocardial viability imaging. In routine PET viability studies, oral glucose and intravenous insulin loading is commonly utilized. In an optimal study, glucose and insulin loading is expected to cause FDG uptake both in hibernating and normal myocardium. However, in routine studies it is not uncommon to see absent or reduced FDG uptake in normal myocardium. In this retrospective study we further analyzed our PET viability images to evaluate FDG uptake status in myocardium under the oral glucose and intravenous insulin loading protocol that we use in our hospital...
April 2018: Journal of the Saudi Heart Association
https://www.readbyqxmd.com/read/29910551/aortocaval-fistula-presenting-as-type-2-acute-myocardial-infarction-in-a-patient-with-severe-arteriopathy
#11
Vivekanand Rajendran, Krishnaswamy Sundararajan, Alice Sawka
Aortocaval fistulas (ACFs) are rare with varied etiologies. Symptoms can be acute or delayed with predominant manifestations being high output cardiac failure. Acute coronary syndrome due to ACF has not been widely reported. We present a case of a 68-year-old male who presented with signs and symptoms suggestive of acute coronary syndrome. This was confirmed by electrocardiogram changes and a rise in cardiac enzymes. A large abdominal aortic aneurysm was diagnosed initially by imaging without evidence of leak or rupture...
May 2018: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/29910055/arterioventricular-interaction-after-coarctation-repair
#12
Elles J Dijkema, Martijn G Slieker, Tim Leiner, Heynric B Grotenhuis
BACKGROUND: Hypertension is common in patients with coarctation of the aorta (CoA), even after successful repair. Increased aortic stiffness has been implicated in the pathology of CoA-associated hypertension. This study aimed to investigate aortic vascular function and its relationship with hypertension in well-repaired CoA-patients at long-term follow-up. Furthermore, we assessed the additive effect of hypertension to adverse arterioventricular coupling associated with increased aortic stiffness...
July 2018: American Heart Journal
https://www.readbyqxmd.com/read/29910007/a-novel-cardiac-hybrid-imaging-using-real-time-transthoracic-echocardiography-and-contrast-enhanced-multi-detector-computed-tomography-chain-of-the-technological-and-scholarly-developments
#13
EDITORIAL
https://www.readbyqxmd.com/read/29909774/cardiovascular-magnetic-resonance-assessment-of-acute-cardiovascular-effects-of-voluntary-apnoea-in-elite-divers
#14
L Eichhorn, J Doerner, J A Luetkens, J M Lunkenheimer, R C Dolscheid-Pommerich, F Erdfelder, R Fimmers, J Nadal, B Stoffel-Wagner, H H Schild, A Hoeft, B Zur, C P Naehle
BACKGROUND: Prolonged breath holding results in hypoxemia and hypercapnia. Compensatory mechanisms help maintain adequate oxygen supply to hypoxia sensitive organs, but burden the cardiovascular system. The aim was to investigate human compensatory mechanisms and their effects on the cardiovascular system with regard to cardiac function and morphology, blood flow redistribution, serum biomarkers of the adrenergic system and myocardial injury markers following prolonged apnoea. METHODS: Seventeen elite apnoea divers performed maximal breath-hold during cardiovascular magnetic resonance imaging (CMR)...
June 18, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29909107/comparative-utilization-and-temporal-trends-in-cardiac-stress-testing-in-u-s-medicare-beneficiaries-with-and-without-chronic-kidney-disease
#15
Charles A Herzog, Tanya Natwick, Shuling Li, David M Charytan
OBJECTIVES: The authors aimed to analyze temporal trends in cardiac stress testing in U.S. Medicare beneficiaries from 2008 to 2012, types of stress testing, and comparative utilization related to the presence and severity of chronic kidney disease (CKD). BACKGROUND: A long-held perception depicts patients with CKD as being treated less intensively for cardiovascular disease than nonrenal patients. We wondered whether use of diagnostic testing for ischemic heart disease is affected by the presence of CKD...
June 8, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29908832/cardiac-resynchronization-therapy-guided-by-cardiac-magnetic-resonance-imaging-a-prospective-single-centre-randomized-study-cmr-crt
#16
Radka Kočková, Kamil Sedláček, Dan Wichterle, Viktor Šikula, Jaroslav Tintěra, Helena Jansová, Alena Pravečková, Renata Langová, Lukáš Krýže, Wael El-Husseini, Markéta Segeťová, Josef Kautzner
BACKGROUND: Cardiac resynchronization therapy (CRT) improves symptoms of heart failure (HF), morbidity and mortality in selected population. The aim of the study was to investigate the impact of cardiac magnetic resonance (CMR)-guided left ventricular (LV) lead placement on clinical outcomes and LV reverse remodelling in CRT recipients. METHODS: Patients with CRT indication were randomized for CMR-guided (CMR group) or electrophysiologically guided (EP group) LV lead placement between 2011 and 2014...
June 6, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29908289/decreased-contractility-and-altered-responses-to-inotropic-agents-in-myocytes-from-tachypacing-induced-heart-failure-canines
#17
BaoXi Gao, Yusheng Qu, Weston Sutherland, Ray W Chui, Kim Hoagland, Hugo M Vargas
Contractility measurements using primary isolated cardiac myocytes (CM) have commonly been used in understanding the physiology and pharmacology of cellular mechanics. In the majority of studies, CM from healthy animals were used, and fewer studies were performed with CM from diseased hearts. To better understand the translational value of contractility on the cellular level of a diseased animal model, myocytes were isolated from left ventricles of a tachypacing-induced heart failure (HF) canine model, and their contractility was measured by recording sarcomere shortening using an image-based IonOptix video system...
June 13, 2018: Journal of Pharmacological and Toxicological Methods
https://www.readbyqxmd.com/read/29908190/transcatheter-aortic-valve-replacement-in-a-patient-with-dextrocardia-and-situs-inversus-totalis
#18
Gregory Pattakos, Michael Chrissoheris, Antonios Halapas, Konstantinos Papadopoulos, Panagiota Kourkoveli, Nikolaos Bouboulis, Stratis Pattakos, Konstantinos Spargias
This report presents the case of an 82 year old male with known dextrocardia and situs inversus totalis who developed increasing dyspnea on exertion and was diagnosed with severe aortic stenosis. Transcatheter aortic valve replacement was decided upon requiring deviation from standard techniques for patients with normal anatomy and left-sided aortic arch. We describe two technical differences required for patients with dextrocardia and right-sided aortic arch which facilitate transcatheter aortic valve replacement in this patient group...
June 13, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29907933/the-effect-of-time-of-flight-and-point-spread-function-modeling-on-82-rb-myocardial-perfusion-imaging-of-obese-patients
#19
Paul K R Dasari, Judson P Jones, Michael E Casey, Yuanyuan Liang, Vasken Dilsizian, Mark F Smith
BACKGROUND: The effect of time-of-flight (TOF) and point spread function (PSF) modeling in image reconstruction has not been well studied for cardiac PET. This study assesses their separate and combined influence on 82 Rb myocardial perfusion imaging in obese patients. METHODS: Thirty-six obese patients underwent rest-stress 82 Rb cardiac PET. Images were reconstructed with and without TOF and PSF modeling. Perfusion was quantitatively compared using the AHA 17-segment model for patients grouped by BMI, cross-sectional body area in the scanner field of view, gender, and left ventricular myocardial volume...
June 15, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29907457/what-may-the-future-hold-for-sports-cardiology
#20
REVIEW
André La Gerche, Aaron Baggish, Hein Heidbuchel, Benjamin D Levine, Dhrubo Rakhit
The field of sports cardiology has advanced significantly over recent times. It has incorporated clinical and research advances in cardiac imaging, electrophysiology and exercise physiology to enable better diagnostic and therapeutic management of our patients. One important endeavour has been to try and better differentiate athletic cardiac remodelling from inherited cardiomyopathies and other pathologies. Whilst our diagnostic tools have improved, there have also been errors resulting from assumptions that the pathological traits observed in the general population would be generalisable to athletic populations...
June 6, 2018: Heart, Lung & Circulation
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