Ashuvinee Elangovan, Emily A Bossart, Ahmed Basudan, Nilgun Tasdemir, Osama Shiraz Shah, Kai Ding, Carolin Meier, Tanya Heim, Carola Neumann, Shireen Attaran, Lauren Brown, Jagmohan Hooda, Lori Miller, Tiantong Liu, Shannon L Puhalla, Grzegorz Gurda, Peter C Lucas, Priscilla F McAuliffe, Jennifer M Atkinson, Adrian V Lee, Steffi Oesterreich
UNLABELLED: Breast cancer is categorized by the molecular and histologic presentation of the tumor, with the major histologic subtypes being No Special Type (NST) and Invasive Lobular Carcinoma (ILC). ILC are characterized by growth in a single file discohesive manner with stromal infiltration attributed to their hallmark pathognomonic loss of E-cadherin ( CDH1 ). Few ILC cell line models are available to researchers. Here we report the successful establishment and characterization of a novel ILC cell line, WCRC-25, from a metastatic pleural effusion from a postmenopausal Caucasian woman with metastatic ILC...
September 17, 2023: bioRxiv