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https://www.readbyqxmd.com/read/27907846/modelling-life-satisfaction-and-adjustment-to-trauma-in-children-exposed-to-ongoing-military-violence-an-exploratory-study-in-palestine
#1
Guido Veronese, Alessandro Pepe, Alaa Jaradah, Feda Al Muranak, Husam Hamdouna
Exposure to war and ongoing political violence increases mental health risks among children, especially in terms of posttraumatic stress disorder (PTSD), and depressive or somatic symptoms. However, an exclusive focus on negative functioning can lead to underestimating the coping abilities and natural potential for adjusting to trauma of war-affected children at different developmental phases. Using structural equation modelling, we tested the extent to which data gathered in a predominantly nonclinical sample of Palestinian children (N=1276) living in refugee camps supported a conceptual model in which the relationship between subjective wellbeing and the effects of trauma is mainly top-down in direction...
November 28, 2016: Child Abuse & Neglect
https://www.readbyqxmd.com/read/27903646/whole-transcriptome-sequencing-identified-a-distinct-subtype-of-acute-lymphoblastic-leukemia-with-predominant-genomic-abnormalities-of-ep300-and-crebbp
#2
Maoxiang Qian, Hui Zhang, Shirley Kow-Yin Kham, Shuguang Liu, Chuang Jiang, Xujie Zhao, Yi Lu, Charnise Goodings, Ting-Nien Lin, Ranran Zhang, Takaya Moriyama, Zhaohong Yin, Zhenhua Li, Thuan Chong Quah, Hany Ariffin, Ah Moy Tan, Shuhong Shen, Deepa Bhojwani, Shaoyan Hu, Suning Chen, Huyong Zheng, Ching-Hon Pui, Allen Eng-Juh Yeoh, Jun J Yang
Chromosomal translocations are a genomic hallmark of many hematologic malignancies. Often as initiating events, these structural abnormalities result in fusion proteins involving transcription factors important for hematopoietic differentiation and/or signaling molecules regulating cell proliferation and cell cycle. In contrast, epigenetic regulator genes are more frequently targeted by somatic sequence mutations, possibly as secondary events to further potentiate leukemogenesis. Through comprehensive whole transcriptome sequencing of 231 children with acute lymphoblastic leukemia (ALL), we identified 58 putative functional and predominant fusion genes in 54...
November 30, 2016: Genome Research
https://www.readbyqxmd.com/read/27887008/can-sluggish-cognitive-tempo-be-distinguished-from-adhd-inattention-in-very-young-children-evidence-from-a-sample-of-korean-preschool-children
#3
SoYean Lee, G Leonard Burns, Stephen P Becker
OBJECTIVE: This study evaluated whether sluggish cognitive tempo (SCT) is separable from ADHD-inattention (IN) and uniquely associated with internalizing dimensions in preschool children in South Korea. METHOD: Mothers of 172 preschool children (ages 4-6 years; 52% girls) rated children's SCT, ADHD-IN, ADHD-hyperactivity/impulsivity (HI), oppositional defiant disorder (ODD), aggression, emotional reactivity, anxiety/depression, somatic complaints, withdrawal, and sleep problems...
November 24, 2016: Journal of Attention Disorders
https://www.readbyqxmd.com/read/27885158/psychosocial-work-environment-in-school-and-students-somatic-health-complaints-an-analysis-of-buffering-resources
#4
Kristina Sonmark, Bitte Modin
AIM: This study explores the association between the psychosocial work environment in school and students' somatic health complaints. With its point of departure from the Demand-Control-Support (DCS) model, the aim was to examine how aspects of decision control and social support can moderate stress-related health implications of high psychological demands. METHODS: Data come from two cross-sectional waves of the Swedish version of Health Behaviour in School-aged Children (HBSC 2005/2006 and 2009/2010), which consists of a total of 9427 11-, 13- and 15-year-old students...
November 23, 2016: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/27883317/somatoform-disorders-a-pediatric-experience
#5
Nada Pop-Jordanova, Tatjana Zorcec
Somatization in children consists of the persistent experience and complaints of somatic distress that cannot be fully explained by a medical diagnosis. Working at the Psychophysiological Department at the University Clinic we are dealing with more than 100 children per year manifesting this kind of disorders. The aim of this article is to summarize some specific characteristics of the somatoform disorder in a group of 243 children, mean age 10.31 (± 2.75) years for both genders, selected randomly. The used psychometric instruments are: CBCL, EPQ for children, and MMPI-201 for mothers...
November 1, 2016: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://www.readbyqxmd.com/read/27876779/mutational-landscape-in-children-with-myelodysplastic-syndromes-is-distinct-from-adults-specific-somatic-drivers-and-novel-germline-variants
#6
V B Pastor, S Hirabayashi, A Karow, J Wehrle, E J Kozyra, R Nienhold, G Ruzaike, D Lebrecht, A Yoshimi, M Niewisch, T Ripperger, G Göhring, I Baumann, S Schwarz, B Strahm, C Flotho, R C Skoda, C M Niemeyer, M W Wlodarski
Leukemia accepted article preview online, 23 November 2016. doi:10.1038/leu.2016.342.
November 23, 2016: Leukemia: Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K
https://www.readbyqxmd.com/read/27876123/blm-germline-and-somatic-pkmyt1-and-ahcy-mutations-genetic-variations-beyond-mycn-and-prognosis-in-neuroblastoma
#7
E M Novak, N S Halley, T M Gimenez, A Rangel-Santos, A M P Azambuja, M Brumatti, P L Pereira, C S C Vince, R R Giorgi, I Bendit, L M Cristofani, V Odone-Filho
Neuroblastoma (NB) is the most common extra cranial solid tumor of childhood and often lethal in childhood. Clinical and biologic characteristics that are independently prognostic of outcome in NB are currently used for risk stratification to optimally the therapy. It includes age at diagnosis, International Neuroblastoma Staging System tumor histopathology and MYCN amplification. However, even in patients with theoretically good prognosis, such as localized tumor and non-amplified MYCN, either disease progress or recurrence may occur...
December 2016: Medical Hypotheses
https://www.readbyqxmd.com/read/27875321/the-impact-of-selected-environmental-behavioral-and-psychosocial-factors-on-schoolchildren-s-somatic-and-mental-health
#8
Diana Vondrova, Daniela Kapsdorfer, Lubica Argalasova, Katarina Hirosova, Martin Samohyl, Ludmila Sevcikova
Children develop rapidly and many exogenous determinants of health significantly affect their somatic and mental development. There is a subjective perception of cognitive load associated with the educational process. The aim of the study is to assess individual environmental, behavioral and psychosocial factors influencing physical health and to investigate the amount of mental load in children. We investigated 87 schoolchildren (47 girls and 40 boys) aged 10-12 years, who were attending primary school in Bratislava...
November 22, 2016: Reviews on Environmental Health
https://www.readbyqxmd.com/read/27866718/mutational-analysis-of-metastatic-lymph-nodes-from-papillary-thyroid-carcinoma-in-adult-and-pediatric-patients
#9
Alexander L Shifrin, Michele Fischer, Trevor Paul, Brian Erler, Katherine Gheysens, Prachi Baodhankar, Joanna W Song-Yang, Samantha Taylor, Venkata Arun Timmaraju, Arthur Topilow, Alidad Mireskandari, Gyanendra Kumar
BACKGROUND: Limited data are available on the analysis of somatic mutations in metastatic lymph nodes in adult and pediatric patients with papillary thyroid carcinomas. METHODS: A total of 92, microdissected, formalin-fixed, paraffin-embedded tissue specimens from 39 patients were analyzed for the presence of somatic mutations utilizing the ThyGenX next-generation sequencing test. RESULTS: Somatic mutations were detected in 67% of papillary thyroid carcinoma specimens...
November 17, 2016: Surgery
https://www.readbyqxmd.com/read/27865992/in-6-to-8-year-old-children-hair-cortisol-is-associated-with-body-mass-index-and-somatic-complaints-but-not-with-stress-health-related-quality-of-life-blood-pressure-retinal-vessel-diameters-and-cardiorespiratory-fitness
#10
Markus Gerber, Katharina Endes, Serge Brand, Christian Herrmann, Flora Colledge, Lars Donath, Oliver Faude, Uwe Pühse, Henner Hanssen, Lukas Zahner
OBJECTIVES: Hair cortisol measurement has become an increasingly accepted approach in endocrinology and biopsychology. However, while in adult research hair cortisol has been proposed as a relevant biomarker for chronic stress (and its adverse consequences), studies with children are scarce. Therefore, the goal of the present exploratory study was to examine the associations between hair cortisol concentrations (HCCs), stress, and a series of health-related outcomes in a sample of Swiss first grade schoolchildren...
November 9, 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/27865065/how-do-we-recognize-the-child-with-osas
#11
Koen F Joosten, Helena Larramona, Silvia Miano, Dick Van Waardenburg, Athanasios G Kaditis, Nele Vandenbussche, Refika Ersu
Obstructive sleep-disordered breathing includes a spectrum of clinical entities with variable severity ranging from primary snoring to obstructive sleep apnea syndrome (OSAS). The clinical suspicion for OSAS is most often raised by parental report of specific symptoms and/or abnormalities identified by the physical examination which predispose to upper airway obstruction (e.g., adenotonsillar hypertrophy, obesity, craniofacial abnormalities, neuromuscular disorders). Symptoms and signs of OSAS are classified into those directly related to the intermittent pharyngeal airway obstruction (e...
November 16, 2016: Pediatric Pulmonology
https://www.readbyqxmd.com/read/27846075/clinical-presentation-of-acute-gastroenteritis-in-children-with-functional-gastrointestinal-disorders
#12
Miguel Saps, Stijn Mintjens, Cenk K Pusatcioglu, Daniel M Cohen, Petra Sternberg
Visceral hypersensitivity (VH) and abnormal coping are common in children with functional abdominal pain disorders (FAPDs). Thus, it would be expected that children with VH would report more pain if their gut is acutely inflamed. Aims- Compare clinical symptoms and somatization of children with and without FAPDs at time of an episode of acute gastroenteritis (AGE). Seventy children with AGE and their parents completed the Rome III Diagnostic Questionnaire for Pediatric Functional GI Disorders and the Children's Somatization Inventory...
November 11, 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27845596/how-can-the-general-practitioner-support-adolescent-children-of-ill-or-substance-abusing-parents-a-qualitative-study-among-adolescents
#13
Frøydis Gullbrå, Tone Smith-Sivertsen, Anette Hauskov Graungaard, Guri Rortveit, Marit Hafting
OBJECTIVES: To explore significant experiences of adolescents as next of kin that the general practitioner (GP) should identify and recognize. DESIGN: Qualitative study with focus-group interviews. SUBJECTS AND SETTING: Three focus-group interviews were conducted with a total of 15 Norwegian adolescents each with an ill or substance-abusing parent. The participants were recruited from existing support groups. RESULTS: The adolescents' days were dominated by unpredictability in their family situation and their own exhausting efforts to keep up an ordinary youth life...
November 15, 2016: Scandinavian Journal of Primary Health Care
https://www.readbyqxmd.com/read/27830427/factors-associated-with-self-injurious-behaviors-in-children-with-autism-spectrum-disorder-findings-from-two-large-national-samples
#14
G N Soke, S A Rosenberg, R F Hamman, T Fingerlin, C R Rosenberg, L Carpenter, L C Lee, E Giarelli, L D Wiggins, M S Durkin, A Reynolds, C DiGuiseppi
In this study, we explored potential associations among self-injurious behaviors (SIB) and a diverse group of protective and risk factors in children with autism spectrum disorder from two databases: Autism and Developmental Disabilities Monitoring (ADDM) Network and the Autism Speaks-Autism Treatment Network (AS-ATN). The presence of SIB was determined from children's records in ADDM and a parent questionnaire in AS-ATN. We used multiple imputation to account for missing data and a non-linear mixed model with site as a random effect to test for associations...
November 9, 2016: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/27824311/-unmet-needs-in-the-recognition-and-treatment-of-childhood-depression
#15
Sandor Kalmar
In spite of the fact that the good mental health is indispensable condition of the development of sound personality, in the past years the somatic and mental state of our children did not improve. The author ascertains that there are several obstacles in the recognition, treatment and prevention of child-depression that causes a serious public health problem. He stresses the neurologic, neuropsychiatric, psychopathological and diagnostic deficiencies, and the low number of Child and Youth Dispensaries. He describes the situation of Hungarian Child and Youth Dispensaries network, and states positively that today the child-psychiatric services are not able to provide optimal provision for every depressive child...
September 2016: Neuropsychopharmacologia Hungarica
https://www.readbyqxmd.com/read/27821200/spousal-influences-on-health-and-well-being-of-older-kuwaiti-men-and-women
#16
Yagoub Y Al-Kandari, Douglas E Crews
The aim of the study was to determine the associations of the self-perceptions of health and social support among Kuwaitis who were 60 years old and older, who either were or were not currently living with a spouse. A sample of 1427 was selected (472 men and 955 women). Social Affairs nurses completed all interviews in the participants' homes. A single questionnaire was designed; SPSS (version 21) was used for data entry and analysis. Participants living with their spouse reported significantly greater social support, more frequent contact with others and greater strength of social relationships than those without a spouse...
November 8, 2016: Journal of Biosocial Science
https://www.readbyqxmd.com/read/27821069/ill-and-substance-abusing-parents-how-can-the-general-practitioner-help-their-children-a-qualitative-study
#17
Frøydis Gullbrå, Tone Smith-Sivertsen, Guri Rortveit, Norman Anderssen, Marit Hafting
BACKGROUND: Severe illness among parents may interfere with their parenting. Children having ill or substance-abusing parents are at risk of own health problems and psychosocial difficulties. The health care system should identify families in need of help and provide the help needed. For ill parents, it can be difficult to seek help and advices for their parenting. The aim of this study was to identify important factors for the general practitioner (GP) to bear in mind during encounters with ill and substance-abusing parents, to enable the GP to provide appropriate support for the children...
November 8, 2016: BMC Family Practice
https://www.readbyqxmd.com/read/27820980/can-improvised-somatic-dance-reduce-acute-pain-for-young-people-in-hospital
#18
Lisa Dowler
Aim This study explores the effects of improvised somatic dance (ISD) on children and young people experiencing acute pain following orthopaedic or cardiac surgery, or post-acquired brain injury. Methods The study involved 25 children and young people and adopted a mixed methods approach. This included a descriptive qualitative approach to help the participants and witnesses verbalise their experience of ISD, and pain scores were assessed before and after ISD using validated pain assessment tools. Data were analysed using descriptive statistical analysis...
November 8, 2016: Nursing Children and Young People
https://www.readbyqxmd.com/read/27815623/facilitating-mental-health-screening-of-war-torn-populations-using-mobile-applications
#19
Bahar Hashemi, Sara Ali, Rania Awaad, Laila Soudi, Lawrence Housel, Stephen J Sosebee
BACKGROUND: War-torn populations are often hard to screen for mental health disorders. Classical data collection approaches, such as paper-based, online, or SMS-operated, are either infeasible or lack accuracy due to a variety of challenges associated with dynamics and consequences of war. METHODS: In this paper, we introduce a novel approach for accurate and fast screening using free open-source software, Open Data Kit (ODK) mobile application. This approach was developed by the Palestine Children's Relief Fund (PCRF) to assess the mental health symptoms of 986 Palestinian children (age 6-18) in the aftermath of Israel's Operation Protective Edge (OPE) in 2014...
November 4, 2016: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/27806547/a-comparative-study-of-quality-of-life-in-infertile-and-fertile-women-referred-to-jahrom-infertility-clinics
#20
Razieh Parnian, Farzad Poorgholami, Nehle Parandavar, Safeih Jamali, Fatemeh Shakeri
INTRODUCTION: Infertility is a medical problem which influences all the dimensions of one's individual and social life and can expose him/her to psycho-physical, socio-economic, sexual and family challenges. This study was designed to compare the quality of life of fertile and infertile women. MATERIALS & METHODOLOGY: This is a case-control analytical study in which 180 fertile and infertile women (aged 18-42) participated. The infertile group consisted of women who had visited an infertility treatment clinic...
August 26, 2016: Global Journal of Health Science
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