Shiori Kumagai, Erika Watanabe, Naoko Hayashi, Yuuri Kimura, Takehiro Kamiya, Ayumi Nagashima, Kazutaka Ushio, Genki Imaizumi, Juhyun Kim, Keijiro Munakata, Takahiro Umezawa, Shigehisa Hirose, Koji Kasai, Toru Fujiwara, Michael F Romero, Akira Kato
Marine teleosts ingest large amounts of seawater containing various ions, including 0.4 mM boric acid, which can accumulate at toxic levels in the body. However, the molecular mechanisms by which marine teleosts absorb and excrete boric acid are not well understood. Aquaporins (Aqps) are homologous to the nodulin-like intrinsic protein (NIP) family of plant boric acid channels. To investigate the potential roles of Aqps on boric acid transport across the plasma membrane in marine teleosts, we analyzed the function of Aqps of Japanese pufferfish (Takifugu rubripes) expressed in Xenopus laevis oocytes...
March 2023: Physiological Reports