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MRA Cerebral

Mei-Ling Sharon Tai, Vijay K Sharma
BACKGROUND: Vascular complications are important causes of cerebral infarction in tuberculous meningitis (TBM).Transcranial Doppler ultrasonography (TCD) is a non-invasive tool that can provide real-time information about cerebral hemodynamics. However, the literature on the role of TCD in the diagnosis or monitoring of vasculopathy associated with TBM is scarce. We explored the role of TCD in the diagnosis and monitoring of TBM-related vasculopathy of the major intracranial arteries...
2016: PloS One
Yuki Shinohara, Ayumi Kato, Eijiro Yamashita, Toshihide Ogawa
BACKGROUND: To evaluate the detectability of arterial acute thrombus on R2* map by iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL) IQ compared with T2*-weighted imaging (T2*WI). METHODS: Twenty-six patients with acute cerebral infarction who underwent R2* map and T2*WI were reviewed. We performed visual assessment of each sequence regarding the visibility of susceptibility effect reflecting acute thrombus and quantitative evaluation of the thrombus on R2* map...
September 2016: Yonago Acta Medica
Daniel L Moellentin, Dale Stewart, James Barbour
A 39-year-old man presented with new onset right hemiparesis and aphasia within an hour of using approximately 120 mL lidocaine 4% topical solution intranasally. Lidocaine had been prescribed over a 3-week period for pain due to multiple debridements of the nasal septum. A total of 650 mL of 4% lidocaine (26 g) had been dispensed to the patient during this time. The patient had a significant history of drug abuse, including snorting crushed tablets. Otherwise he was a healthy man with no chronic diseases or conditions...
September 2016: Hospital Pharmacy
Yu-Ching Cheng, Hung-Chieh Chen, Chen-Hao Wu, Yi-Ying Wu, Ming-His Sun, Wen-Hsien Chen, Jyh-Wen Chai, Clayton Chi-Chang Chen
BACKGROUND: Traditional digital subtraction angiography (DSA) is currently the gold standard diagnostic method for the diagnosis and evaluation of cerebral arteriovenous malformation (AVM) and dural arteriovenous fistulas (dAVF). OBJECTIVES: The aim of this study was to analyze different less invasive magnetic resonance angiography (MRA) images, time-resolved MRA (TR-MRA) and three-dimensional time-of-flight MRA (3D TOF MRA) to identify their diagnostic accuracy and to determine which approach is most similar to DSA...
April 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
M Trolliet, A Sevely, J-F Albucher, N Nasr, C Hachon Lecamus, K Deiva, E Cheuret
Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by thunderclap headaches with diffuse segmental constriction of cerebral arteries that resolves spontaneously within 3 months. We report on a case of a 13-year-old boy presenting with acute severe headaches, triggered by physical exertion. His past medical history was uneventful. Moderate headache persisted between exacerbations for 4 weeks. He secondarily presented with signs of intracranial hypertension. Brain magnetic resonance angiography (MRA) revealed multifocal narrowing of the cerebral arteries...
September 14, 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
Angela E Rankine-Mullings, Courtney R Little, Marvin E Reid, Deanne P Soares, Carolyn Taylor-Bryan, Jennifer M Knight-Madden, Susan E Stuber, Asha V Badaloo, Karen Aldred, Margaret E Wisdom-Phipps, Teresa Latham, Russell E Ware
BACKGROUND: Cerebral vasculopathy in sickle cell anemia (SCA) begins in childhood and features intracranial arterial stenosis with high risk of ischemic stroke. Stroke risk can be reduced by transcranial doppler (TCD) screening and chronic transfusion therapy; however, this approach is impractical in many developing countries. Accumulating evidence supports the use of hydroxyurea for the prevention and treatment of cerebrovascular disease in children with SCA. Recently we reported that hydroxyurea significantly reduced the conversion from conditional TCD velocities to abnormal velocities; whether hydroxyurea can be used for children with newly diagnosed severe cerebrovascular disease in place of starting transfusion therapy remains unknown...
September 12, 2016: JMIR Research Protocols
Nitin Agarwal, Giulio Zuccoli, Geoffrey Murdoch, Brian T Jankowitz, Stephanie Greene
INTRODUCTION: Developmental venous anomalies (DVAs) are cited as the most common cerebral vascular malformations. Still, intracerebral hematomas are rarely thought to be caused by DVAs. In this report, the authors present a unique case of a DVA that hemorrhaged spontaneously, rather than hemorrhaging into a venous infarction following DVA thrombosis as has been more commonly reported. CLINICAL PRESENTATION: A 22-year-old previously healthy male presented to the emergency department with a severe headache, confusion, and progressive hemiparesis...
September 9, 2016: Neuroradiology Journal
Kerri A Nottage, Russell E Ware, Banu Aygun, Matthew Smeltzer, Guolian Kang, Joseph Moen, Winfred C Wang, Jane S Hankins, Kathleen J Helton
Silent cerebral infarction (SCI) is the most common neurological abnormality among children with sickle cell anaemia (SCA). The effect of hydroxycarbamide (also termed hydroxyurea) on the development and progression of SCI is unclear. We evaluated brain magnetic resonance imaging/angiography (MRI/MRA) in children with SCA receiving long-term hydroxycarbamide therapy. Fifty participants (median 9·4 years, range 1·1-17·3) enrolled in the Hydroxyurea Study of Long-Term Effects (HUSTLE; NCT00305175) underwent brain MRI/MRA and laboratory evaluations before hydroxycarbamide initiation and after 3 and 6 years of treatment to maximum tolerated dose...
October 2016: British Journal of Haematology
Yoichiro Ikushima, Takashi Hashido, Yoshiyuki Watanabe, Tsukasa Doi
PURPOSE: To quantitatively investigate in vitro the effects of flip angle (FA), receiver bandwidth (BW), echo time (TE), and magnetic field strength (FS) on image noise and artifacts induced by stent-assisted coiling on contrast-enhanced MR angiography (CE-MRA) images, as a first step towards optimization of imaging parameters. METHODS: A phantom simulating a cerebral aneurysm treated using stent-assisted coiling was filled with diluted gadolinium contrast medium, and MR angiography were obtained using varied parameters: FA (10°-60°), BW (164-780 Hz/pixel), and FS (1...
September 6, 2016: Magnetic Resonance in Medical Sciences: MRMS
Jiaxin Wang, Shifeng Zhao, Zifeng Liu, Yun Tian, Fuqing Duan, Yutong Pan
Cerebral vessel segmentation is essential and helpful for the clinical diagnosis and the related research. However, automatic segmentation of brain vessels remains challenging because of the variable vessel shape and high complex of vessel geometry. This study proposes a new active contour model (ACM) implemented by the level-set method for segmenting vessels from TOF-MRA data. The energy function of the new model, combining both region intensity and boundary information, is composed of two region terms, one boundary term and one penalty term...
2016: Computational and Mathematical Methods in Medicine
Ashish Kulhari, Ashley Rogers, Han Wang, Vishakhadatta Mathur Kumaraswamy, Wei Xiong, Michael DeGeorgia
BACKGROUND: Despite the common occurrence of hymenopteran stings worldwide, primary neurologic manifestations including stroke are rare. We report a case of a healthy male who developed a right middle cerebral artery (MCA) territory ischemic stroke after getting stung by a wasp. CASE REPORT: A 44-year-old man with hypertension presented to the hospital with sudden-onset left hemiparesis, left facial weakness, and dysarthria after being stung by a wasp. Magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA) scans of the brain revealed a right MCA territory infarct and a lack of flow in the distal right internal carotid artery and MCA...
October 2016: Journal of Emergency Medicine
Yorito Hattori, Jun-Ichiro Enmi, Satoshi Iguchi, Satoshi Saito, Yumi Yamamoto, Kazuyuki Nagatsuka, Hidehiro Iida, Masafumi Ihara
The bilateral common carotid artery stenosis (BCAS) mouse model, which replicates chronic cerebral hypoperfusion and white matter ischemic lesions, is considered to model some aspects of vascular cognitive impairment. Cerebral blood flow (CBF) changes in the brain surface post-BCAS have been demonstrated by laser speckle flowmetry, but CBF levels in the brain parenchyma remain unknown. Adult C57BL/6J male mice were subjected to BCAS using external microcoils. Brain magnetic resonance angiography (MRA) was conducted to visualize the intracranial main arteries while arterial spin labeling (ASL) was used to measure cortical and subcortical parenchymal CBF levels before and after BCAS...
2016: Scientific Reports
Jose Enrique Alonso Formento, Jose Luis Fernández Reyes, Blanca Mar Envid Lázaro, Teresa Fernández Letamendi, Ryth Yeste Martín, Francisco José Jódar Morente
Internal carotid artery dissection (ICAD) is a rare entity that either results from traumatic injury or can be spontaneously preceded or not by a minor trauma such as sporting activities. It represents a major cause of stroke in young patients. The diagnosis should be suspected with the combination of Horner's syndrome, headache or neck pain, and retinal or cerebral ischaemia. The confirmation is frequently made with a magnetic resonance angiography (MRA). Although anticoagulation with heparin followed by vitamin-K-antagonists is the most common treatment, there is no difference in efficacy of antiplatelet and anticoagulant drugs at preventing stroke and death in patients with symptomatic carotid dissection...
2016: Case Reports in Neurological Medicine
Qiang Zhang, Zhiqiang Zhang, Jiakang Yang, Qi Sun, Yongchun Luo, Tonghui Shan, Hao Zhang, Jingfeng Han, Chunyang Liang, Wenlong Pan, Chuanqi Gu, Gengsheng Mao, Ruxiang Xu
Digital subtracted angiography (DSA) remains the gold standard for diagnosis of cerebral vascular diseases and provides intraprocedural guidance. This practice involves extensive usage of x-ray and iodinated contrast medium, which can induce side effects. In this study, we examined the accuracy of 3-dimensional (3D) registration of magnetic resonance angiography (MRA) and DSA imaging for cerebral vessels, and tested the feasibility of using preprocedural MRA for real-time guidance during endovascular procedures...
August 2016: Medicine (Baltimore)
Yahya Guvenc, Adnan Demirci, Deniz Billur, Sevim Aydin, Ersin Ozeren, Pinar Bayram, Alper Dilli, Emre Cemal Gokce, Onur Yaman, Haydar Celik, Mete Karatay, Fatih Alagoz, Erkan Kaptanoglu
Background This study investigated the effect of Punica granatum L. (pomegranate) juice on the rabbit basilar artery in an experimental subarachnoid hemorrhage (SAH) model. Methods Eighteen adult male New Zealand white rabbits were randomly divided into three groups: a control group (n = 6), SAH group (n = 6), and SAH + treatment group (n = 6). Basilar artery diameter was measured with magnetic resonance angiography (MRA) in all groups at the beginning of the study. Experimental SAH was created by injecting autologous arterial blood into the cisterna magna...
August 10, 2016: Journal of Neurological Surgery. Part A, Central European Neurosurgery
Nolan S Hartkamp, J Hendrikse, Laurens J L De Cocker, Gert Jan de Borst, L Jaap Kappelle, Reinoud P H Bokkers
PURPOSE: Cerebral perfusion territories are known to vary widely among individuals. This may lead to misinterpretation of the symptomatic artery in patients with ischaemic stroke to a wrong assumption of the underlying aetiology being thromboembolic or hypoperfusion. The aim of the present study was to investigate such potential misinterpretation with territorial arterial spin labelling (T-ASL) by correlating infarct location with imaging of the perfusion territory of the carotid arteries or basilar artery...
October 2016: Journal of Neurology, Neurosurgery, and Psychiatry
Björn Reuter, Alexander Venus, Patrick Heiler, Lothar Schad, Anne Ebert, Michael G Hennerici, Saskia Grudzenski, Marc Fatar
BACKGROUND: Cerebral amyloid angiopathy (CAA) is characterized by extracellular deposition of amyloid β (Aβ) around cerebral arteries and capillaries and leads to an increased risk for vascular dementia, spontaneous lobar hemorrhage, convexal subarachnoid hemorrhage, and transient focal neurological episodes, which might be an indicator of imminent spontaneous intracerebral hemorrhage. In CAA cerebral microbleeds (cMBs) with a cortical/juxtacortical distribution are frequently observed in standard magnetic resonance imaging (MRI)...
2016: Frontiers in Aging Neuroscience
L A Kalashnikova, M V Dreval', L A Dobrynina, M V Krotenkova
Authors describe a 7-year-old boy, who developed a severe right-sided hemiparesis, aphasia, seizure, and confusion state during sport games. There was no headache. Allergic dermatitis in the past medical history and influenza vaccination 2 weeks before stroke were recorded. On the 12th day of disease, MRI of the brain revealed an acute infarction in the territory of left anterior and middle cerebral arteries with hemorrhagic transformation. MPA (15 day) showed occlusion of the left ACA and MCA. HR-MRI T1_db_fs weighted imaging (36 day) found intramural hematoma (IMH) in ACA and MCA with marked stenosis of the lumen...
2016: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
Catherine Amlie-Lefond, Dennis Shaw
The child presenting with possible sentinel transient ischemic event or stroke requires prompt diagnosis so that strategies to limit injury and prevent recurrent stroke can be instituted. Cerebral arteriopathy is a potent risk factor for arterial ischemic stroke in childhood. Though acute imaging study in the setting of possible stroke is often a head computed tomography, when possible magnetic resonance imaging (MRI) is recommended as the first-line study as confirmation and imaging evaluation of ischemic stroke will typically require MRI...
2016: Handbook of Clinical Neurology
Makoto Obara, Osamu Togao, Masami Yoneyama, Tomoyuki Okuaki, Shuhei Shibukawa, Hiroshi Honda, Marc Van Cauteren
PURPOSE: A new approach for intracranial MR angiography (MRA) is introduced, using acceleration-selective arterial spin labeling (AccASL). The aim of this study was to investigate the arterial visualization and venous suppression using AccASL. METHODS: Intracranial MRA images obtained by AccASL and time-of-flight (TOF) were compared in seven healthy volunteers and one patient with occlusion of the terminal portion of the left internal carotid artery. The volunteer images were assessed by measuring the contrast-to-noise ratio (CNR) between the middle cerebral artery (MCA) and white matter (WM) and between the confluence of sinuses and WM...
July 15, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
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