keyword
https://read.qxmd.com/read/38644486/comparative-analysis-of-ventricular-stiffness-across-species
#1
REVIEW
Yuu Usui, Akira Hanashima, Ken Hashimoto, Misaki Kimoto, Momoko Ohira, Satoshi Mohri
Investigating ventricular diastolic properties is crucial for understanding the physiological cardiac functions in organisms and unraveling the pathological mechanisms of cardiovascular disorders. Ventricular stiffness, a fundamental parameter that defines ventricular diastolic functions in chordates, is typically analyzed using the end-diastolic pressure-volume relationship (EDPVR). However, comparing ventricular stiffness accurately across chambers of varying maximum volume capacities has been a long-standing challenge...
April 2024: Physiological Reports
https://read.qxmd.com/read/38628553/%C3%AF-zhangixalusthaoae-sp-nov-a-new-green-treefrog-species-from-vietnam-anura-rhacophoridae
#2
JOURNAL ARTICLE
Tao Thien Nguyen, Huy Hoang Nguyen, Hoa Thi Ninh, Linh Tu Hoang Le, Hai Tuan Bui, Nikolai Orlov, Chung Van Hoang, Thomas Ziegler
We describe a new treefrog species from Lao Cai Province, northwestern Vietnam. The new species is assigned to the genus Zhangixalus based on a combination of the following morphological characters: (1) dorsum green, smooth; body size medium (SVL 30.1-32.2 in males); (2) fingers webbed; tips of digits expanded into large disks, bearing circum-marginal grooves; (3) absence of dermal folds along limbs; (4) absence of supracloacal fold and tarsal projection. The new species can be distinguished from its congeners by: (1) dorsal surface of the head and body green without spots; (2) axilla and groin cream with a black blotch; (3) ventral cream without spot; (4) chin creamy with grey marbling; anterior part of the thigh and ventral surface of tibia orange without spots; posterior parts of thigh orange with a large black blotch; (5) ventral side of webbing orange with some grey pattern (6) iris red-bronze, pupils black; (7) finger webbing formula I1¼-1¼II1-2III1-1IV, toe webbing formula I½-½II0-1½III¼-1¾IV1¾-½V...
2024: ZooKeys
https://read.qxmd.com/read/38616154/comparing-color-match-by-conventional-trial-and-error-method-with-maxillofacial-spectrophotometer-method-for-the-skin-of-indian-participants-a-subjective-and-objective-assessment
#3
JOURNAL ARTICLE
Sunayana A, Saumyendra Vikram Singh, Sunit Kumar Jurel, Lakshya Kumar, Atul Srivastava
STATEMENT OF PROBLEM: The comparative accuracy of different color-matching methods for maxillofacial prostheses is lacking. PURPOSE: This clinical study aimed to compare prosthesis color matching using the conventional trial and error method with that using the maxillofacial spectrophotometer method. MATERIAL AND METHODS: Fifty-four Indian participants were enrolled based on skin color and divided into Light, Medium, and Dark groups (n=18)...
April 13, 2024: Journal of Prosthetic Dentistry
https://read.qxmd.com/read/38588985/liver-lipidomics-analysis-revealed-the-protective-mechanism-of-zuogui-jiangtang-qinggan-formula-in-type-2-diabetes-mellitus-with-non-alcoholic-fatty-liver-disease
#4
JOURNAL ARTICLE
Min Zhou, Xiu Liu, Yongjun Wu, Qin Xiang, Rong Yu
ETHNOPHARMACOLOGICAL RELEVANCE: Hepatic steatosis, a hallmark of non-alcoholic fatty liver disease (NAFLD), represents a significant global health issue. Liver lipidomics has garnered increased focus recently, highlighting Traditional Chinese Medicine's (TCM) role in mitigating such conditions through lipid metabolism regulation. The Zuogui Jiangtang Qinggan Formula (ZGJTQGF), a longstanding TCM regimen for treating Type 2 Diabetes Mellitus (T2DM) with NAFLD, lacks a definitive mechanism for its lipid metabolism regulatory effects...
April 6, 2024: Journal of Ethnopharmacology
https://read.qxmd.com/read/38588984/xiaozhi-formula-attenuates-non-alcoholic-fatty-liver-disease-by-regulating-lipid-metabolism-via-activation-of-ampk-and-ppar-pathways
#5
JOURNAL ARTICLE
Liping You, Tao Wang, Wenxuan Li, Jinghao Zhang, Chao Zheng, Yanxi Zheng, Suyin Li, Zhi Shang, Jiacheng Lin, Fang Wang, Yihan Qian, Zhijia Zhou, Xiaoni Kong, Yueqiu Gao, Xuehua Sun
BACKGROUND: Xiaozhi formula (XZF) is a practical Chinese herbal formula for the treatment of non-alcoholic fatty liver disease (NAFLD), which possesses an authorized patent certificate issued by the State Intellectual Property Office of China (ZL202211392355.0). However, the underlying mechanism by which XZF treats NAFLD remains unclear. PURPOSE: This study aimed to explore the main component of XZF and its mechanism of action in NAFLD treatment. METHODS: UHPLC-Q-Orbitrap HRMS was used to identify the components of the XZF...
April 6, 2024: Journal of Ethnopharmacology
https://read.qxmd.com/read/38585587/sudan-black-poisoning-resulted-in-methemoglobinemia-in-a-baby-with-congenital-chyloperitoneum
#6
Helgi Padari, Karin Kipper, Imbi Eelmäe, Jekaterina Nerman, Mare Lintrop, Tuuli Metsvaht
Treatment of congenital chyloperitoneum is a challenge. Conservative methods may be ineffective. Preoperative visualization of the site of lymphatic leakage is crucial, but radiological imaging is technically complicated and may not provide sufficient information, especially in small patients. To ease the detection of lymphatic leakage during surgery, preoperative feeding with fat-rich formula with Sudan Black has been recommended. However, administration of Sudan Black may result in life-threatening methemoglobinemia and liver damage without any advantage of revealing leakage during surgery...
April 2024: Clinical Case Reports
https://read.qxmd.com/read/38575377/percutaneous-nephrostomy-as-a-procedure-in-the-treatment-of-urinary-tract-obstruction-experiences-in-the-university-clinic-of-urology-in-skopje
#7
JOURNAL ARTICLE
Aleksandar Trifunovski, Galina Severova, Ana Atanasova, Josif Janculev, Viktor Stankov, Sotir Stavridis, Skender Saidi, Aleksandra Gavrilovska Brzanov, Martina Ambardjieva, Sasho Dohchev
INTRODUCTION: Obstructive uropathy encompasses various urinary tract obstructions, leading to changes in urine flow, kidney pressure, and impaired kidney function. Predicting renal recovery from obstructive uropathy, can be challenging and necessitates treatment, as in percutaneous nephrostomy (PNS) drainage. The choice of drainage method depends on patient-specific factors and local expertise. According to the data for the Republic of North Macedonia, in the register of the European Renal Association, in the last few years, there has been an increase in the percentage of patients with obstructive nephropathy from 7...
March 1, 2024: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://read.qxmd.com/read/38573561/fundamental-aspects-of-the-molecular-topology-of-fuchsine-acid-dye-with-connection-numbers
#8
JOURNAL ARTICLE
Ali N A Koam, Ali Ahmad, Shahid Zaman, Ibtisam Masmali, Haleemah Ghazwani
Fuchsine acid serves as a supramolecular dye in Masson's trichrome stain, finding extensive applications in histology. It is also utilized with picric acid in Van Gieson's method to reveal red collagen fibers and in Masson's trichrome to highlight smooth muscle in contrast to collagen. Beyond these applications, it plays a crucial role in electronic fields and photonic devices as an organic semiconductor. Therefore, investigating and predicting the complex molecular structure of fuchsine acid becomes essential, serving as the foundation for understanding its physicochemical features...
April 4, 2024: European Physical Journal. E, Soft Matter
https://read.qxmd.com/read/38566602/adjustment-of-optical-absorption-in-phosphorene-through-electron-phonon-coupling-and-an-electric-field
#9
JOURNAL ARTICLE
Do C Hap, Le P Q Hung, Luong T Tung, Le T T Phuong, Tran Cong Phong
This study investigates the optical absorption of monolayer phosphorene, focusing on its response to the electron-phonon coupling (EPC) and an electric field. Using a tight-binding Hamiltonian model based on the Barišic-Labbe-Friedel-Su-Schrieffer-Heeger model and the Kubo formula, we calculate the electronic band structure and optical absorption characteristics. The anisotropic dispersion of carriers along armchair and zigzag directions leads to distinct optical responses. Positive and negative EPC effects increase and decrease hopping parameters, respectively, enlarging and reducing/closing the band gap...
April 3, 2024: Physical Chemistry Chemical Physics: PCCP
https://read.qxmd.com/read/38551833/unraveling-sources-of-emission-heterogeneity-in-silicon-vacancy-color-centers-with-cryo-cathodoluminescence-microscopy
#10
JOURNAL ARTICLE
Daniel K Angell, Shuo Li, Hendrik Utzat, Matti L S Thurston, Yin Liu, Jeremy Dahl, Robert Carlson, Zhi-Xun Shen, Nicholas Melosh, Robert Sinclair, Jennifer A Dionne
Diamond color centers have proven to be versatile quantum emitters and exquisite sensors of stress, temperature, electric and magnetic fields, and biochemical processes. Among color centers, the silicon-vacancy (SiV[Formula: see text]) defect exhibits high brightness, minimal phonon coupling, narrow optical linewidths, and high degrees of photon indistinguishability. Yet the creation of reliable and scalable SiV[Formula: see text]-based color centers has been hampered by heterogeneous emission, theorized to originate from surface imperfections, crystal lattice strain, defect symmetry, or other lattice impurities...
April 2, 2024: Proceedings of the National Academy of Sciences of the United States of America
https://read.qxmd.com/read/38535754/structure-and-morphology-of-red-pigments-based-on-sepiolite
#11
JOURNAL ARTICLE
I Carrillo, E Atanes-Sánchez, F Fernández-Martínez
Sepiolite is an important raw fibrous material. A method to prepare red pigments based on sepiolite through the thermal treatment of sepiolite with sulfur and sodium sulfide hydrate is reported. Sepiolite was heated until 800 °C in order to remove zeolitic water, the first coordinated water, the second coordinated water, and structural hydroxyls. Several [S/Na2 S]molar ratios in the range 0.5-7 were employed. The properties of these pigments were studied by different analytical techniques, such as colorimetric analysis, thermal analysis, Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction and scanning electron microscopy...
March 27, 2024: Dalton Transactions: An International Journal of Inorganic Chemistry
https://read.qxmd.com/read/38504539/mechanisms-of-dangua-fang-in-multi-target-and-multi-method-regulation-of-glycolipid-metabolism-based-on-phosphoproteomics
#12
JOURNAL ARTICLE
Heng Xianpei, Wang Zhita, L I Liang, Yang Liuqing, Huang Suping, Jin Lang, H E Weidong
OBJECTIVE: To explore the mechanism of Dangua Fang (, DGR) in multi-target and multi-method regulation of glycolipid metabolism based on phosphoproteomics. METHODS: Sprague-Dawley rats with normal glucose levels were randomly divided into three groups, including a conventional diet control group (Group A), high-fat-high-sugar diet model group (Group B), and DGR group (Group C, high-fat-high-sugar diet containing 20.5 g DGR). After 10 weeks of intervention, the fasting blood glucose (FBG), 2 h blood glucose [PBG; using the oral glucose tolerance test (OGTT)], hemoglobin A1c (HbA1c), plasma total cholesterol (TC), and triglycerides (TG) were tested, and the livers of rats were removed to calculate the liver index...
April 2024: Journal of Traditional Chinese Medicine
https://read.qxmd.com/read/38504436/clinical-efficacy-and-gut-microbiota-regulating-related-effect-of-si-jun-zi-decoction-in-postoperative-non-small-cell-lung-cancer-patients-a-prospective-observational-study
#13
JOURNAL ARTICLE
Yiyun He, Ao Qi, Yifeng Gu, Congmeng Zhang, Yichao Wang, Wenxiao Yang, Ling Bi, Yabin Gong, Lijing Jiao, Ling Xu
BACKGROUND: Postoperative non-small cell lung cancer (NSCLC) patients frequently encounter a deteriorated quality of life (QOL), disturbed immune response, and disordered homeostasis. Si-Jun-Zi Decoction (SJZD), a well-known traditional Chinese herbal formula, is frequently employed in clinical application for many years. Exploration is underway to investigate the potential therapeutic effect of SJZD for treating postoperative NSCLC. OBJECTIVE: To assess the efficacy of SJZD on QOLs, hematological parameters, and regulations of gut microbiota in postoperative NSCLC patients...
2024: Integrative Cancer Therapies
https://read.qxmd.com/read/38500195/kangxianling-formula-attenuates-renal-fibrosis-by-regulating-gut-microbiota
#14
JOURNAL ARTICLE
Pengyu Tao, Haiyan Liu, Guangjian Hou, Jianrao Lu, Yukun Xu
BACKGROUND: Renal fibrosis (RF) produced adverse effect on kidney function. Recently, intestinal dysbiosis is a key regulator that promotes the formation of renal fibrosis. This study will focus on exploring the protective mechanism of Kangxianling Formula (KXL) on renal fibrosis from the perspective of intestinal flora. METHODS: Unilateral Ureteral Obstruction (UUO) was used to construct rats' model with RF, and receive KXL formula intervention for 1 week...
March 18, 2024: European Journal of Medical Research
https://read.qxmd.com/read/38481550/hepatic-transcriptome-discloses-the-potential-targets-of-xuefu-zhuyu-decoction-ameliorating-non-alcoholic-fatty-liver-disease-induced-by-high-fat-diet
#15
JOURNAL ARTICLE
Hao Tang, Jun Wang, Yi Fang, Yixiao Yin, Wei Liu, Yiyang Hu, Jinghua Peng
BACKGROUND AND AIM: Xuefu Zhuyu decoction (XZD), a traditional Chinese medicinal formula, was firstly recorded in the Qing dynasty of ancient China and previously demonstrated to ameliorate hepatic steatosis. In the present study, the effects of XZD on non-alcoholic fatty liver disease (NAFLD) induced by high-fat diet (HFD) were evaluated in mice and the hepatic transcriptome was detected to disclose the potential mechanisms of XZD. EXPERIMENTAL PROCEDURE: The effects of XZD (low- and high-dosage) on NAFLD induced by HFD for 16 weeks were evaluated...
March 2024: Journal of Traditional and Complementary Medicine
https://read.qxmd.com/read/38480501/red-yeast-rice-and-statin-therapy-in-patients-with-hypercholesterolemia-and-the-comorbidities-a-retrospective-cohort-study-on-lipid-lowering-effects-and-cardiovascular-outcomes
#16
JOURNAL ARTICLE
Tun-Pin Hsueh, Wan-Ling Lin, Wen-Long Hu, Yu-Chiang Hung
Red yeast rice (RYR) is known for its lipid-lowering effects in patients with hypercholesterolemia; however, its comparative efficacy with statins and risk reduction remains uncertain. This retrospective study analyzed data from 337,104 patients with hyperlipidemia in the Chang Gung Research Database cohort, spanning from January 2016 to December 2021. Exclusion criteria were applied to ensure data completeness and compliance, including an age limit of [Formula: see text] years, absence of RYR or statin treatment, and a treatment duration of [Formula: see text] days...
March 14, 2024: American Journal of Chinese Medicine
https://read.qxmd.com/read/38479546/yunvjian-decoction-mitigates-hyperglycemia-in-rats-induced-by-a-high-fat-diet-and-streptozotocin-via-reducing-oxidative-stress-in-pancreatic-beta-cells
#17
JOURNAL ARTICLE
Jie Lv, Meng Su, Yansong Wang, Juan Yang, Yanni Liang, Lin Chen, Liyan Lei
ETHNOPHARMACOLOGICAL RELEVANCE: Yunvjian (YNJ), a traditional Chinese herbal formula first reported in Jing Yue Quan Shu, is commonly used in the clinical treatment of type 2 diabetes mellitus (T2DM). However, the mechanism by which YNJ affects T2DM remains unclear. AIM OF THE STUDY: This study aimed to assess the therapeutic effects of YNJ on T2DM and explore the potential mechanism involved. MATERIALS AND METHODS: High-performance liquid chromatography (HPLC) was used to identify the chemical compounds of YNJ...
March 11, 2024: Journal of Ethnopharmacology
https://read.qxmd.com/read/38474482/formulation-optimization-and-performance-prediction-of-red-mud-particle-adsorbents-based-on-neural-networks
#18
JOURNAL ARTICLE
Longjiang Li, Yalan Wang, Wenyuan Wang
Red mud (RM), a bauxite residue, contains hazardous radioactive wastes and alkaline material and poses severe surface water and groundwater contamination risks, necessitating recycling. Pretreated RM can be used to make adsorbents for water treatment. However, its performance is affected by many factors, resulting in a nonlinear correlation and coupling relationship. This study aimed to identify the best formula for an RM adsorbent using a mathematical model that examines the relationship between 11 formulation types (e...
February 22, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/38448355/microwave-disinfection-of-facial-silicone-prostheses-part-1-color-stability
#19
JOURNAL ARTICLE
Penchanok Santhaveesuk, Pensiri Saenthaveesuk, Julian Nathaniel Holland, Sudarat Kiat-Amnuay
STATEMENT OF PROBLEM: The choice of cleaning method is an important consideration for lengthening the serviceable time of facial prostheses as microbial organisms and biofilms could degrade facial prostheses and cause skin irritation. Whether microwave disinfection is a suitable cleaning method without degradation of the properties of a prosthesis is unclear. PURPOSE: The purpose of this in vitro study was to measure the color stability of 6 commonly used facial silicone elastomers after microwave disinfection over a simulated 1...
March 5, 2024: Journal of Prosthetic Dentistry
https://read.qxmd.com/read/38447467/fast-and-sustainable-planar-yeast-based-bioassay-for-endocrine-disruptors-in-complex-mixtures-start-of-cell-cultivation-to-result-within-one-day
#20
JOURNAL ARTICLE
Alisa Ronzheimer, Anne E Ringelmann, Gertrud E Morlock
High-performance thin-layer chromatography hyphenated with planar multiplex bioassays and high-resolution tandem mass spectrometry contributes to the non-target detection or even identification of active compounds in complex mixtures such as food, feed, cosmetics, commodities, and environmental samples. It can be used to discover previously unknown harmful or active substances in complex samples and to tentatively assign molecular formulas. This method is already faster than the commonly used in vitro assays along with liquid chromatographic separations, but overnight cell cultivation still prevents a planar bioassay from being performed within one day...
February 10, 2024: Talanta
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