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Shun Nishino, Masanori Nishimura, Yujiro Asada, Atsushi Yamashita, Yoshisato Shibata
BACKGROUND: Aortic regurgitation (AR) associated with detachment of the aortic valve commissure is extremely rare. We present a case of progressively worsening severe chronic AR due to detachment of the aortic valve commissure during hospitalization that was confirmed with multimodality imaging. CASE SUMMARY: A 50-year-old male with Marfan syndrome visited our hospital to receive treatment for cholelithiasis. Pre-operative examination revealed severe AR and aortic root aneurysm...
April 2024: European Heart Journal. Case Reports
#2
Dylan Hengst, Daniel Kandah, Ravinder Dervesh, Michael Ellerman, Justin Ugwu, Jennifer Goerbig-Campbell, Dwayne Campbell
Eosinophilic myocarditis (EM) is a rare but potentially fatal complication of sustained eosinophilia that is characterized by eosinophilic infiltration into myocardial tissue. There are various etiologies of EM that can be classified into general categories: reactive, clonal, and idiopathic. We present a case of EM caused by chronic eosinophilic leukemia, a rare myeloproliferative neoplasm that frequently presents with sustained peripheral eosinophilia. This case displays several serious complications of EM, including recurrent ventricular tachycardia storm, cardiogenic shock, and mural thrombus formation despite anticoagulation...
March 2024: Curēus
#3
JOURNAL ARTICLE
Amanda Pereira da Cruz, Gloria Martins, Camila Marinelli Martins, Victoria Marques, Samantha Christovam, Denise Battaglini, Chiara Robba, Paolo Pelosi, Patricia Rieken Macedo Rocco, Fernanda Ferreira Cruz, Cynthia Dos Santos Samary, Pedro Leme Silva
BACKGROUND: Non-invasive respiratory support (conventional oxygen therapy [COT], non-invasive ventilation [NIV], high-flow nasal oxygen [HFNO], and NIV alternated with HFNO [NIV + HFNO] may reduce the need for invasive mechanical ventilation (IMV) in patients with COVID-19. The outcome of patients treated non-invasively depends on clinical severity at admission. We assessed the need for IMV according to NIV, HFNO, and NIV + HFNO in patients with COVID-19 according to disease severity and evaluated in-hospital survival rates and hospital and intensive care unit (ICU) lengths of stay...
April 22, 2024: European Journal of Medical Research
#4
JOURNAL ARTICLE
Yinong Chen, Shuai Zhang, Xin Lu, Wanmu Xie, Chen Wang, Zhenguo Zhai
BACKGROUND: Patients with congenital myopathies may experience respiratory involvement, resulting in restrictive ventilatory dysfunction and respiratory failure. Pulmonary hypertension (PH) associated with this condition has never been reported in congenital ryanodine receptor type 1(RYR1)-related myopathy. CASE PRESENTATION: A 47-year-old woman was admitted with progressively exacerbated chest tightness and difficulty in neck flexion. She was born prematurely at week 28...
April 22, 2024: BMC Pulmonary Medicine
#5
JOURNAL ARTICLE
Amirreza Sajjadieh Khajouei, Pedram Payandeh, Sayed Ali Emami, Manizheh Danesh
INTRODUCTION: Anomalous origin of the right coronary artery from the left sinus of Valsalva (R-ACAOS) is a relatively rare condition that can potentially lead to devastating outcomes. The current study aims to investigate the cardiac-related disorders among patients with incidental R-ACAOS diagnosis through computed tomography angiography (CTA). METHODS: The current cross-sectional study has been conducted on 50 patients diagnosed with R-ACAOS who underwent CTA...
April 20, 2024: International Journal of Cardiology
#6
JOURNAL ARTICLE
Abel A Pavía-López, José A Magaña-Serrano, José A Cigarroa-López, Adolfo Chávez-Mendoza, José L Mayorga-Butrón, Diego Araiza-Garaygordobil, Juan B Ivey-Miranda, Gustavo F Méndez-Machado, Héctor González-Godínez, Luisa F Aguilera-Mora, Antonio Jordán-Ríos, Luis Olmos-Domínguez, Marcos J Olalde-Román, Emma M Miranda-Malpica, Zuilma Vázquez-Ortiz, Jorge Rayo-Chávez, Alexandra A Mendoza, Manlio F Márquez-Murillo, Sergio A Chávez-Leal, Amada Álvarez-San Gabriel, Marissa A Silva-García, Alex D Pacheco-Bouthiller, Jorge A Aldrete-Velazco, Carlos A Guizar-Sánchez, Efraín Gaxiola-López, Arturo Guerra-López, Lourdes Figueiras-Graillet, Gustavo Sánchez-Miranda, Genaro H Mendoza-Zavala, Moisés Aceves-García, Adolfo Chávez-Negrete, Marisol Arroyo-Hernández, Bertha B Montaño-Velázquez, Luis F Romero-Moreno, María M Baquero-Hoyos, Liliana Velasco-Hidalgo, Ana L Rodríguez-Lozano, Nancy E Aguilar-Gómez, Mario Rodríguez-Vega, Jorge E Cossío-Aranda
Chronic heart failure continues to be one of the main causes of impairment in the functioning and quality of life of people who suffer from it, as well as one of the main causes of mortality in our country and around the world. Mexico has a high prevalence of risk factors for developing heart failure, such as high blood pressure, diabetes, and obesity, which makes it essential to have an evidence-based document that provides recommendations to health professionals involved in the diagnosis and treatment of these patients...
2024: Archivos de Cardiología de México
#7
JOURNAL ARTICLE
Omar Elkattawy, Keanaan Malke, David Mothy, Aaron Tran, Sherif Elkattawy, Sayeeda Rab, Ammar Zidat, Omar Mohamed, Fayez Shamoon
Introduction Pre-eclampsia is a pregnancy-associated multisystem disorder; in rare cases, it can be complicated by arrhythmias such as ventricular tachycardia (VT). The purpose of this study was to determine the prevalence and predictors of VT among patients admitted with pre-eclampsia as well as to analyze the independent association of VT with in-hospital outcomes in this population. Methods Data were obtained from the National Inpatient Sample from January 2016 to December 2019. Patients with a primary diagnosis of pre-eclampsia were selected using International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM) codes...
March 2024: Curēus
#8
Arno A van de Bovenkamp, Deborah N Kalkman, Marcel A M Beijk, Mariëlle C van de Veerdonk
BACKGROUND: We present a case of a pregnant patient with recurrent angina, in which her symptoms were initially attributed to coronary artery spasm. However, during follow-up, she was diagnosed as having pheochromocytoma, a rare neuroendocrine tumour. CASE SUMMARY: The 35-year-old patient was admitted to the hospital because of chest pain and elevated cardiac troponins after the use of MDMA. Physical examination, electrocardiogram, echocardiography, coronary angiogram, and cardiac MRI were normal...
April 2024: European Heart Journal. Case Reports
#9
JOURNAL ARTICLE
Jean-Sébastien Hulot, Philip Janiak, Philippe Boutinaud, Pierre Boutouyrie, Frédérique Chézalviel-Guilbert, Jean-Joseph Christophe, Ariel Cohen, Thibaud Damy, Juliette Djadi-Prat, Hüseyin Firat, Pierre-Yves Hervé, Richard Isnard, Guillaume Jondeau, Elie Mousseaux, Mathieu Pernot, Pierre Prot, Benoit Tyl, Gilles Soulat, Damien Logeart
BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous syndrome that is poorly defined, reflecting an incomplete understanding of its pathophysiology. AIM: To redefine the phenotypic spectrum of HFpEF. METHODS: The PACIFIC-PRESERVED study is a prospective multicentre cohort study designed to perform multidimensional deep phenotyping of patients diagnosed with HFpEF (left ventricular ejection fraction≥50%), patients with heart failure with reduced ejection fraction (left ventricular ejection fraction≤40%) and subjects without overt heart failure (3:2:1 ratio)...
April 12, 2024: Archives of Cardiovascular Diseases
#10
JOURNAL ARTICLE
Inki Moon, Su Yeong Park, Dongon Kim, Minae Park, Sojeong Park, Seong Soon Kwon, Min Gyu Kong, Hyun Woo Park, Hyung Oh Choi, Jon Suh, Yoon Haeng Cho, Nae Hee Lee, Hye-Sun Seo
BACKGROUND: Regarding the pathophysiology of renal infarction (RI), cardioembolic causes could have large proportion. However, there are notable variations in prevalence of atrial fibrillation (AF) among patients with RI across different studies, ranging from 17 to 65%. The primary objective of this study is to analyze the incidence of AF in patients with RI. METHODS: This nationwide retrospective cohort study enrolled 5200 patients with RI from the Korean National Institute of Health Services database spanning the years 2013 to 2019...
April 19, 2024: International Journal of Cardiology
#11
JOURNAL ARTICLE
Peng Hu, Zhedong Wan, Qianhui Sun, Peng Teng, Liang Ma
BACKGROUND: Sinus of Valsalva aneurysm (SVA) is a rare cardiac anomaly which can be congenital or acquired. Patients with SVA are commonly asymptomatic when the occupying effect of SVA is insignificant, while ruptured SVA usually causes severe symptoms including heart failure and myocardial ischemia. CASE PRESENTATION: We present an unusual case of a 64-year-old female manifesting with exertional dyspnea as well as angina pectoris for three months. Echocardiography and cardiac computed tomographic angiography confirmed unruptured left-coronary and non-coronary SVAs...
April 20, 2024: Journal of Cardiothoracic Surgery
#12
JOURNAL ARTICLE
Matteo Landolfo, Francesco Spannella, Federico Giulietti, Chiara Di Pentima, Piero Giordano, Elisabetta Borioni, Laura Landi, Mirko Di Rosa, Roberta Galeazzi, Riccardo Sarzani
AIM: Diagnosing and classifying heart failure (HF) in the oldest-old patients has technical and interpretation issues, especially in the acute setting. We assessed the usefulness of both N-terminal pro-brain natriuretic peptide (NT-proBNP) and lung ultrasound (LUS) for confirming HF diagnosis and predicting, among hospitalized HF patients, those with reduced ejection fraction (HFrEF). METHODS: We performed a cross-sectional study on 148 consecutive patients aged ≥ 80 years admitted to our Internal Medicine and Geriatrics ward with at least one symptom/sign compatible with HF and NT-proBNP ≥ 125 pg/mL...
April 20, 2024: BMC Geriatrics
#13
JOURNAL ARTICLE
Yuqi Hong, Ziting Gao, Hongye Wei, Yajing Wei, Ziyi Qiu, Jun Xiao, Wuqing Huang
PURPOSE: The effect of obesity on the development of heart failure (HF) has received attention, and this study intends to further explore the bidirectional association between body size or composition and HF by using Mendelian Randomization (MR) approach. DESIGN: We performed a two-sample bidirectional MR study to investigate the association between body size or composition and the risk of HF using aggregated data from genome-wide association studies. Univariable MR analysis was used to investigate the causal relationship, and multivariable MR analysis was used to explore the mediating role of general and central obesity in the relationship between body size or composition and HF...
April 18, 2024: International Journal of Cardiology
#14
JOURNAL ARTICLE
S Shao, H Liao, S Zhou, Y Li, H Yu, X Dai, Q Zhu, Y Hua, C Wang, K Zhou
OBJECTIVES: To uncover the clinical course of fetal isolated non-immune mediated second-degree AVB and determine the factors associated with the spontaneous recovery for fetal non-immune second-degree atrioventricular block (AVB). METHODS: A total of 20 fetuses with isolated, non-immune mediated second-degree AVB were prospectively recruited between 2014 and 2022. These fetuses were divided into the spontaneous recovery group (n=12) and the non-spontaneous recovery group (n=8)...
April 20, 2024: Ultrasound in Obstetrics & Gynecology
#15
JOURNAL ARTICLE
Peng Xiao, Jinchao Chen, Peize Wu, Weifei Zhang, Zepeng Sun, Jian Ma, Hongmei Li
N-Terminal pro-B-type natriuretic peptide (NT-proBNP) is a pivotal biomarker for the diagnosis and prognosis of heart failure (HF). However, no SI-traceable certified reference material (CRM) or reference measurement procedure (RMP) is available for this biomarker, and so clinical testing results obtained in different laboratories cannot be traced to a higher-order standard, leading to incomparable measurements. Protein hydrolysis and protein cleavage isotope dilution mass spectrometry (AAA-IDMS and PepA-IDMS) were used to develop a CRM...
April 20, 2024: Analytical and Bioanalytical Chemistry
#16
REVIEW
Zhihua Liu, Xi Zhao
Cardiovascular diseases (CVD) represent one of the most considerable global health threats, owing to their high incidence and mortality rates. Despite the ongoing advancements in detection, prevention, treatment, and prognosis of CVD, which have resulted in a decline in both incidence and mortality rates, CVD remains a major public health concern. Therefore, novel diagnostic biomarkers and therapeutic interventions are imperative to minimise the risk of CVD. Non-coding RNAs (ncRNAs) have recently gained increasing attention, with PIWI-interacting RNAs (piRNAs) emerging as a class of small ncRNAs traditionally recognised for their role in silencing transposons within cells...
April 7, 2024: Biochemical and Biophysical Research Communications
#17
JOURNAL ARTICLE
Ding Wu, Xiao-Ming Yi, Hui-Xian Wei, Ke-Xin Zhang, Chang-Jie Shi, Xiu-Quan Shi, Zhen-Yu Xu, Dian Fu
OBJECTIVE: To investigate the clinical effect and safety of transurethral 1470 nm semiconductor laser vaporization and cutting in the treatment of super high age and high risk benign prostatic hyperplasia. METHODS: The clinical data of 38 patients with super-high-risk prostate who underwent transurethral surgery in our hospital from April 2016 to December 2017 were retrospectively analyzed. All patients had obvious progressive dysuria. The diagnosis of benign prostatic hyperplasia was confirmed by urinary color Doppler ultrasound, anal finger examination, PSA, prostate biopsy, etc...
September 2023: Zhonghua Nan Ke Xue, National Journal of Andrology
#18
Stefano Guarracini, Pierluigi Di Sebastiano, Fabio Francesco Di Mola, Raffaella Di Renzo, Lorenzo Mazzocchetti, Antonio M Calafiore, Michele Di Mauro
A 74-year-old man with advanced heart failure was admitted to the hospital with a diagnosis of colorectal cancer, and he underwent surgery. To maintain stable hemodynamics, the Impella CP device was used. The patient was weaned from the device shortly after surgery, and he had an uneventful postoperative course. This case may pave the way for non-procrastinating surgery in patients with poorly stable hemodynamics.
2024: Frontiers in Cardiovascular Medicine
#19
Linda Massoud, Katarina Westling, Marie Fischer, Emil Najjar
BACKGROUND: Following infection with severe acute respiratory syndrome coronavirus, a post-infectious multisystem inflammatory syndrome in adults (MIS-A) has been identified. It affects multiple organ systems and can lead to multi-organic failure. CASE SUMMARY: This case report describes a patient with MIS-A with significant cardiac involvement including peri-myocarditis, pulmonary hypertension, right-sided heart failure, tricuspid regurgitation, and cardiogenic shock...
December 2023: European Heart Journal. Case Reports
#20
REVIEW
Megan Wilson, Abdullah Al-Hamid, Ismail Abbas, Jason Birkett, Iftikhar Khan, Matthew Harper, Dhiya Al-Jumeily Obe, Sulaf Assi
AIMS: To perform a systematic review of studies that sought to identify diagnostic biomarkers for the diagnosis of cardiovascular diseases (CVDs) and diabetes mellitus (DM), which could be used in low- and middle-income countries (LMICs) where there is a lack of diagnostic equipment, treatments and training. MATERIALS AND METHODS: Papers were sourced from six databases: the British Nursing Index, Google Scholar, PubMed, Sage, Science Direct and Scopus. Articles published between January 2002 and January 2023 were systematically reviewed by three reviewers and appropriate search terms and inclusion/exclusion criteria were applied...
April 18, 2024: Diabetes, Obesity & Metabolism
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