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https://www.readbyqxmd.com/read/29781677/community-health-workers-in-lesotho-experiences-of-health-promotion-activities
#1
Thato Seutloali, Lizeka Napoles, Nomonde Bam
BACKGROUND: Lesotho adopted primary health care in 1979, and community health workers (CHWs) were included in the programme to focus on health promotion, particularly to reach people in underserved rural areas. Although the CHW programme has been successful, the heavy burden of disease because of HIV and/or AIDS and tuberculosis shifted resources from health promotion to home-based care. AIM: The study explored the lived experience of CHWs in conducting health promotion activities in Lesotho...
February 27, 2018: African Journal of Primary Health Care & Family Medicine
https://www.readbyqxmd.com/read/29780677/the-2016-southeastern-us-drought-an-extreme-departure-from-centennial-wetting-and-cooling
#2
A Park Williams, Benjamin I Cook, Jason E Smerdon, Daniel A Bishop, Richard Seager, Justin S Mankin
The fall 2016 drought in the southeastern United States (SE US) appeared exceptional based on its widespread impacts, but the current monitoring framework that only extends from 1979-present does not readily facilitate evaluation of soil-moisture anomalies in a centennial context. A new method to extend monthly gridded soil-moisture estimates back to 1895 is developed, indicating that since 1895, October-November 2016 soil moisture (0-200 cm) in the SE US was likely the second lowest on record, behind 1954...
October 27, 2017: Journal of Geophysical Research. Atmospheres: JGR
https://www.readbyqxmd.com/read/29777601/-informed-consent-something-unresolved-in-the-penitentiary-setting
#3
Julio García Guerrero
INTRODUCTION: The exercise of Informed Consent within the penitentiary environment contradicts the ordinary exercise of the same towards the rest of the population. METHODOLOGY: review of legal regulations and constitutional doctrine on IC. Review of the judicial outcomes when a prisoner refuses medical treatment. RESULTS: Normative on IC (Ley 41/2002 y Convenio de Oviedo, Spanish legal framework): with the exception of cases in which IC cannot be taken or under the risk of causong damage to third parties, competent and capable persons can decide over their life and health, and such decisions need to be respected...
May 2018: Cuadernos de Bioética: Revista Oficial de la Asociación Española de Bioética y Ética Médica
https://www.readbyqxmd.com/read/29777447/integra-%C3%A2-dermal-regeneration-template-and-split-thickness-skin-grafting-a-therapy-approach-to-correct-aplasia-cutis-congenita-and-epidermolysis-bullosa-in-carmi-syndrome
#4
Julian Trah, Christina Has, Ingrid Hausser, Heinz Kutzner, Konrad Reinshagen, Ingo Königs
The association of junctional epidermolysis bullosa with pyloric atresia (JEB-PA) and aplasia cutis congenita (ACC) was described by El Shafie et al. (J Pediatr Surg 14(4):446-449, 1979) and Carmi et al. (Am J Med Genet 11:319-328, 1982). Most patients die in the first weeks of life, and no curative treatment options are available so far. We describe a patient with JEB-PA and ACC (OMIM # 226730) who was treated for extensive areas of ACC by Integra® -Dermal Regeneration Template and split-thickness skin grafting (STSG)...
May 18, 2018: Dermatology and Therapy
https://www.readbyqxmd.com/read/29776115/electroclinic-effect-in-the-chiral-lamellar-%C3%AE-phase-of-a-lyotropic-liquid-crystal
#5
Marc D Harjung, Frank Giesselmann
In thermotropic chiral Sm-A^{*} phases, an electric field along the smectic layers breaks the D_{∞} symmetry of the Sm-A^{*} phase and induces a tilt of the liquid crystal director. This so-called electroclinic effect (ECE) was first reported by Garoff and Meyer in 1977 and attracted substantial scientific and technological interest due to its linear and submicrosecond electro-optic response [S. Garoff and R. B. Meyer, Phys. Rev. A 19, 338 (1979)0556-279110.1103/PhysRevA.19.338]. We now report the observation of an ECE in the pretransitional regime from a lyotropic chiral lamellar L_{α}^{*} phase into a lyo-Sm-C^{*} phase, the lyotropic analog to the thermotropic Sm-C^{*} phase which was recently discovered by Bruckner et al...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29773783/cholesteryl-ester-storage-disease-fatal-outcome-without-causal-therapy-in-a-female-patient-with-the-preventable-sequelae-of-progressive-liver-disease-after-many-years-of-mild-symptoms
#6
Ali Canbay, Meike N Müller, Stathis Philippou, Guido Gerken, Andreas Tromm
BACKGROUND Cholesteryl ester storage disease (CESD), also known as lysosomal acid lipase deficiency (LAL-D), is a rare autosomal-recessive inheritable lysosomal storage disease. Since 2015, a causal treatment with sebelipase alfa, which replaces the missing LAL enzyme, has been approved. We report a fatal course of LAL-D in a female patient. CASE REPORT In 1979, CESD was first diagnosed in a 13-year-old female with marked hepatomegaly. At that time, no specific treatment for CESD was available and the spontaneous course of the disease had to be awaited...
May 18, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29770176/the-top-50-most-cited-articles-on-total-ankle-arthroplasty-a-bibliometric-analysis
#7
Azeem Tariq Malik, Shahryar Noordin
Total Ankle Arthroplasty (TAA) is a relatively new and evolving field in Foot and Ankle surgery. We conducted a citation analysis to identify the characteristics of the top 50 most cited articles on total ankle arthroplasty. Using the Web of Science database and the search strategy total ankle arthroplasty OR total ankle replacement , we identified 2445 articles. After filtering for relevant articles, the top 50 cited articles on total ankle arthroplasty were retrieved for descriptive and statistical analysis...
March 29, 2018: Orthopedic Reviews
https://www.readbyqxmd.com/read/29770057/aids-in-canada-surveillance-report-2016
#8
L Jonah, A C Bourgeois, M Edmunds, A Awan, O Varsaneux, W Siu
Background: Although there continues to be a global epidemic of people living with human immunodeficiency virus (HIV) there has been a decrease in the number of people dying of acquired immunodeficiency syndrome (AIDS), largely due to successful treatment with antiretroviral therapy. Objective: To provide a descriptive overview of the reported cases of AIDS in Canada by identifying trends by geographic location, sex, age group and mortality. While the descriptive analysis focuses on the year 2016, results are presented for reported cases from the beginning of national AIDS surveillance in 1979...
December 7, 2017: Canada Communicable Disease Report, Relevé des Maladies Transmissibles Au Canada
https://www.readbyqxmd.com/read/29765262/a-new-notomastus-annelida-capitellidae-species-from-korean-waters-with-genetic-comparison-based-on-three-gene-markers
#9
Man-Ki Jeong, Ho Young Soh, Jin Hee Wi, Hae-Lip Suh
Notomastus koreanus sp. n. , collected from the sublittoral muddy bottom of Korean waters, is described as a new species. The Korean new species closely resembles N. torquatus Hutchings & Rainer, 1979 in the chaetal arrangement and the details of abdominal segments, but differs in the position of genital pores and the absence of eyes. DNA sequences (mtCOI, 16S rRNA, and histone H3) of the new species were compared with all the available sequences of Notomastus species in the GenBank database. Three genes showed significant genetic differences between the new species and its congeners (COI: 51...
2018: ZooKeys
https://www.readbyqxmd.com/read/29756089/the-international-association-for-the-study-of-pain-definition-of-pain-as-valid-in-2018-as-in-1979-but-in-need-of-regularly-updated-footnotes
#10
Rolf-Detlef Treede
Milton Cohen, John Quintner, and Simon van Rysewyk proposed a revision of the IASP definition of pain of 1979. This commentary summarizes, why this proposal is useful for guiding assessment of pain, but not its definition.
March 2018: Pain Reports (Baltimore, Md.)
https://www.readbyqxmd.com/read/29756088/situating-pain-in-a-more-helpful-place
#11
Mike Osborn
Milton Cohen et al. proposed a revision of the IASP definition of pain of 1979. This commentary summarizes, why this redefinition is necessary, appropriate, and timely.
March 2018: Pain Reports (Baltimore, Md.)
https://www.readbyqxmd.com/read/29752678/the-number-weight-illusion
#12
Wolf Schwarz, Dennis Reike
When objects are manually lifted to compare their weight, then smaller objects are judged to be heavier than larger objects of the same physical weights: the classical size-weight illusion (Gregory, 2004). It is also well established that increasing numerical magnitude is strongly associated with increasing physical size: the number-size congruency effect e.g., (Besner & Coltheart Neuropsychologia, 17, 467-472 1979); Henik & Tzelgov Memory & Cognition, 10, 389-395 1982). The present study investigates the question suggested by combining these two classical effects: if smaller numbers are associated with smaller size, and objects of smaller size appear heavier, then are numbered objects (balls) of equal weight and size also judged as heavier when they carry smaller numbers? We present two experiments testing this hypothesis for weight comparisons of numbered (1 to 9) balls of equal size and weight, and report results which largely conform to an interpretation in terms of a new "number-weight illusion"...
May 11, 2018: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/29751440/impact-of-forest-maintenance-on-water-shortages-hydrologic-modeling-and-effects-of-climate-change
#13
Pingping Luo, Meimei Zhou, Hongzhang Deng, Jiqiang Lyu, Wenqiang Cao, Kaoru Takara, Daniel Nover, S Geoffrey Schladow
The importance of water quantity for domestic and industrial water supply, agriculture, and the economy more broadly has led to the development of many water quantity assessment methods. In this study, surface flow and soil water in the forested upper reaches of the Yoshino River are compared using a distributed hydrological model with Forest Maintenance Module under two scenarios; before and after forest maintenance. We also examine the impact of forest maintenance on these variables during extreme droughts...
February 15, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29746277/skin-paddles-improve-muscle-flap-salvage-rates-after-microvascular-compromise-in-lower-extremity-reconstruction
#14
John T Stranix, Adam Jacoby, Z-Hye Lee, Lavinia Anzai, Pierre B Saadeh, Vishal Thanik, Jamie P Levine
PURPOSE: Free tissue transfer after lower extremity trauma is associated with notoriously high complication rates. Theoretically, the inclusion of a cutaneous paddle on muscle free flaps may improve clinical flap monitoring. The effect of skin paddle presence on muscle free flap salvage outcomes after take-back was examined. METHODS: Retrospective query of our institutional free-flap registry (1979-2016) identified 362 muscle-based flaps performed for soft tissue coverage after below-knee trauma...
April 30, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29745346/orodispersible-films-a-systematic-patent-review
#15
Ashwini Deshpande, Chaitrali Gijare
BACKGROUND: In Recent years, oral film technology is aimed by the research groups. Oral film technology (OFT) has gained much attention among all the oral drug delivery systems. Fast dissolving film, fast disintegrating film and orodispersible film are some alternative words for this dosage form. Without a need of liquid for administration this dosage form dissolves in the mouth. Typically, fast dissolving film dissolves from 1 to 30 seconds. OBJECTIVE: At the root of this originality, many researchers patented their work on the aspect of orodispersible films using different drugs, polymers, excipients and employing methods of preparation...
May 8, 2018: Recent Patents on Drug Delivery & Formulation
https://www.readbyqxmd.com/read/29743167/characterising-the-adipose-inflammatory-microenvironment-in-male-breast-cancer
#16
Tom Lees, Angharad Cullinane, Alexandra Condon, Abeer M Shaaban, Matthew Humphries, Valerie Speirs
Male breast cancer (MBC) incidence seems to parallel global increases in obesity. The stromal microenvironment contributes to carcinogenesis, yet the role of adipocytes in this is understudied in MBC. We identified 4 cohorts of male breast tissues diagnosed when obesity was rare (archival cohort) and more common (contemporary cohort). We examined the microenvironment of archival and contemporary cohorts of MBC, diagnosed 1940 - 1970 and 1998 - 2006, respectively, with 2 cohorts of, archival and contemporary gynaecomastia, diagnosed 1940 - 1979 and 1996 - 2011, respectively serving as controls...
May 9, 2018: Endocrine-related Cancer
https://www.readbyqxmd.com/read/29742929/trends-in-the-quality-of-work-presented-at-the-society-of-british-neurological-surgeons-meetings-1975-to-2010
#17
John M Pallot, Halima Choonara, Elliot Gerrard, Kanna K Gnanalingham, Benjamin M Davies
BACKGROUND: The quality of scientific publications in clinical journals is well studied but the quality of work presented at medical conferences less so. AIMS: To describe trends in the quality of presentations at the Society of British Neurological Surgeons [SBNS] conference between 1975 and 2010 and the factors associated with higher quality work in order to consider what might improve publication rates. METHODS: Analysis was conducted in 5-year time periods (i...
May 9, 2018: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/29740430/multilayer-control-of-b-cell-activation-by-the-b-cell-antigen-receptor-following-themes-initiated-with-bill-paul
#18
REVIEW
Anthony L DeFranco
This article describes the work I did in Bill Paul's lab as a postdoctoral fellow between 1979 and 1983, and to a lesser extent puts that work in the context of other work on B cell activation and antibody responses that was going on in Bill's lab at that time and shortly beforehand, including the discovery of interleukin 4. In addition, this work describes the subsequent and continuing work in my own lab following-up on themes I began during my time working directly with Bill. A particular emphasis was on understanding the biochemical mechanisms of signaling by the B cell antigen receptor (BCR) to the interior of the B cell...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29737158/hexabromocyclododecane-hbcdd-flame-retardant-in-top-predator-fish-across-canada-and-its-36-year-temporal-trends-for-lake-ontario
#19
Guanyong Su, Daryl McGoldrick, Mandi G Clark, Marlene Evans, Melissa Gledhill, Christine Garron, Alain Armellin, Sean Backus, Robert J Letcher
Hexabromocyclododecane (HBCDD) is a high concern environmental pollutant due to its persistent, bioaccumulative and toxic properties. The spatial distribution of HBCDD was investigated in top predator fish (Lake Trout, Walleye or Brook Trout) collected in 2013 (n=165) from nineteen sampling sites and in 2015 (n=145) from twenty sites across Canada. HBCDD was measurable in at least one sample at each sampling site regardless of sampling year with the exception of Walleye from the south basin of Lake Winnipeg (2013)...
May 8, 2018: Environmental Science & Technology
https://www.readbyqxmd.com/read/29736421/exquisite-response-to-intravenous-immunoglobulin-in-susac-syndrome-during-pregnancy
#20
Enrique Gomez-Figueroa, Sofia Garcia-Trejo, Raul Anwar Garcia-Santos, Gerardo Quiñones-Pesqueira, Juan Manuel Calleja-Castillo
Introduction: From its initial report on two female patients in 1979 by J.O. Susac, Susac syndrome (SuS) or SICRET (small infarctions of cochlear, retinal and encephalic tissue) has persisted as an elusive entity. To date the available evidence for its treatment is based on case reports and case series. The largest systematic review described only 304 reported cases since the 1970s. Here we presented the first reported case to our knowledge in Mexican population and the unusual presentation in a pregnant patient...
March 2018: ENeurologicalSci
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