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https://www.readbyqxmd.com/read/29130619/a-feasibility-study-of-transaxillary-tavi-with-the-lotus-valve
#1
Sagar N Doshi, Sudhakar George, Chun Shing Kwok, Anthony Mechery, Mamas Mamas, Peter F Ludman, Jonathan N Townend, Moninder Bhabra
OBJECTIVES: To assess the feasibility of axillary transcatheter aortic valve implantation (TAVI) using the Lotus valve. BACKGROUND: TAVI is used to treat patients with severe aortic stenosis, with transfemoral (TF) access being the safest and most widely used route. In patients unsuitable for this, there are reports that the axillary artery may be safest alternative access route. The Lotus device is a fully retrievable 2nd generation transcatheter heart valve which is licensed for femoral and transaortic access...
November 11, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29124371/rare-earth-and-precious-elements-in-the-urban-sewage-sludge-and-lake-surface-sediments-under-anthropogenic-influence-in-the-republic-of-benin
#2
Arouna Yessoufou, Binessi Edouard Ifon, Fidèle Suanon, Biaou Dimon, Qian Sun, Comlan Achille Dedjiho, Daouda Mama, Chang-Ping Yu
Nowadays, sewage sludge and water bodies are subjected to heavy pollution due to rapid population growth and urbanization. Heavy metal pollution represents one of the main challenges threatening our environment and the ecosystem. The present work aims to evaluate the contamination state of the sewage sludge and lake sediments in the Republic of Benin. Twenty metallic elements including 15 rare earth elements (Eu, Sb, Cs, Nd, Pr, Gd, La, Ce, Tb, Sm, Dy, Ho, Eu, Yb, and Lu) and five precious elements (Ag, Au, Pd, Pt, and Ru) were investigated using inductive plasma-mass spectrometry...
November 9, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29123976/advanced-glycation-end-products-reduce-the-calcium-transient-in-cardiomyocytes-by-increasing-production-of-reactive-oxygen-species-and-nitric-oxide
#3
Zeinab Hegab, Tamer M A Mohamed, Nicholas Stafford, Mamas Mamas, Elizabeth J Cartwright, Delvac Oceandy
Advanced glycation end products (AGE) are central to the development of cardiovascular complications associated with diabetes mellitus. AGE may alter cellular function through cross-linking of cellular proteins or by activating the AGE receptor (RAGE). However, the signalling molecules involved during AGE stimulation in cardiomyocytes remain unclear. Here, we investigated the effects of AGE treatment on intracellular calcium homeostasis of isolated cardiomyocytes and studied the activation of signalling molecules involved in this process...
November 2017: FEBS Open Bio
https://www.readbyqxmd.com/read/29101851/structure-antioxidative-potency-and-potential-scavenging-of-oh-and-ooh-of-phenylethyl-3-4-dihydroxyhydrocinnamate-in-protic-and-aprotic-media-dft-study
#4
Olivier Holtomo, Mama Nsangou, Jean Jules Fifen, Ousmanou Motapon
DFT methods including B3LYP, B3PW91 and M05-2x associated to 6-31+G(d,p) were used for the structural and antioxidant potency studies of phenylethyl-3,4-dihydroxy-hydrocinnamate (PDH). Solvents were employed according to their protric and aprotic character. So, calculated structures agree with the experimental data. O4H4 is propitious to scavenge radicals whatever the medium except in water where O3H3 and O4H4 are competitive. The explicit solvents of dichloromethane (DCM) and water present a disparity of OH bond dissociation enthalpy and free energy (BDE and BDFE)...
October 28, 2017: Journal of Molecular Graphics & Modelling
https://www.readbyqxmd.com/read/29080997/long-term-use-of-angiotensin-converting-enzyme-inhibitors-protects-against-bone-loss-in-african-american-elderly-men
#5
Nahid Rianon, Catherine G Ambrose, Hannah Pervin, Melissa Garcia, Scherezade K Mama, Ann V Schwartz, Brendan Lee, Tamara Harris
Greater bone mineral density was observed after treating hypertension using angiotensin-converting enzyme inhibitor (ACEi). We report decreased rate of bone loss in hypertensive black men using ACEi for 9 years. There may be a gender- and race-specific effect of ACEi in the prevention of age-associated bone loss. PURPOSE: There is evidence of bone mass preservation in patients receiving ACEis, commonly used to treat hypertension. However, limitations of previous studies include being cross-sectional or only including a short-term follow-up of patients using ACEi and including patients with diabetes, which affects bone metabolism...
October 28, 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/29058578/temporal-dynamic-of-malaria-in-a-suburban-area-along-the-niger-river
#6
Mahamadou Soumana Sissoko, Kourane Sissoko, Bourama Kamate, Yacouba Samake, Siaka Goita, Abdoulaye Dabo, Mama Yena, Nadine Dessay, Renaud Piarroux, Ogobara K Doumbo, Jean Gaudart
BACKGROUND: Even if rainfall and temperature are factors classically associated to malaria, little is known about other meteorological factors, their variability and combinations related to malaria, in association with river height variations. Furthermore, in suburban area, urbanization and growing population density should be assessed in relation to these environmental factors. The aim of this study was to assess the impact of combined environmental, meteorological and hydrological factors on malaria incidence through time in the context of urbanization...
October 23, 2017: Malaria Journal
https://www.readbyqxmd.com/read/29042426/relative-survival-after-transcatheter-aortic-valve-implantation-how-do-patients-undergoing-transcatheter-aortic-valve-implantation-fare-relative-to-the-general-population
#7
Glen P Martin, Matthew Sperrin, William Hulme, Peter F Ludman, Mark A de Belder, William D Toff, Oras Alabas, Neil E Moat, Sagar N Doshi, Iain Buchan, John E Deanfield, Chris P Gale, Mamas A Mamas
BACKGROUND: Transcatheter aortic valve implantation (TAVI) is indicated for patients with aortic stenosis who are intermediate-high surgical risk. Although all-cause mortality rates after TAVI are established, survival attributable to the procedure is unclear because of competing causes of mortality. The aim was to report relative survival (RS) after TAVI, which accounts for background mortality risks in a matched general population. METHODS AND RESULTS: National cohort data (n=6420) from the 2007 to 2014 UK TAVI registry were matched by age, sex, and year to mortality rates for England and Wales (population, 57...
October 17, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29032131/association-between-type-2-diabetes-and-all-cause-hospitalization-and-mortality-in-the-uk-general-heart-failure-population-stratification-by-diabetic-glycemic-control-and-medication%C3%A2-intensification
#8
Claire A Lawson, Peter W Jones, Lucy Teece, Sandra B Dunbar, Petar M Seferovic, Kamlesh Khunti, Mamas Mamas, Umesh T Kadam
OBJECTIVES: This study sought to investigate in the general heart failure (HF) population, whether the associations between type 2 diabetes (T2D) and risk of hospitalization and death, are modified by changing glycemic or drug treatment intensity. BACKGROUND: In the general HF population, T2D confers a higher risk of poor outcomes, but whether this risk is modified by the diabetes status is unknown. METHODS: A nested case-control study in an incident HF database cohort (2002 to 2014) comparing patients with T2D with those without, for risk of all-cause first hospitalization and death...
October 4, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28974150/production-on-hold-delaying-vocal-production-enhances-the-production-effect-in-free-recall
#9
Yaniv Mama, Michal Icht
The Production Effect (PE) represents superior memory for produced (read aloud) relative to non-produced (silently read) items. Another method of improving memory is taking a test on the study material - the Testing Effect. We evaluated the combined influence of both effects on free recall memory, using delayed vocal production, in which study words were vocally produced only after their disappearance. Such procedure involves an initial instant test since participants had to vocally retrieve the words (rather than read them aloud)...
October 3, 2017: Memory
https://www.readbyqxmd.com/read/28971537/editorial-navigating-the-rough-seas-of-anemia-caught-between-the-devil-and-the-deep-blue-sea
#10
EDITORIAL
Mamas A Mamas, Sunil V Rao
No abstract text is available yet for this article.
October 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/28965096/effect-of-weekend-admission-on-process-of-care-and-clinical-outcomes-for-the-management-of-acute-coronary-syndromes-a-retrospective-analysis-of-three-uk-centres
#11
Glen P Martin, Tim Kinnaird, Matthew Sperrin, Richard Anderson, Amr Gamal, Avais Jabbar, Chun Shing Kwok, Diane Barker, Grant Heatlie, Azfar G Zaman, Mamas A Mamas
OBJECTIVES: The effect of weekend versus weekday admission following acute coronary syndrome (ACS) on process of care and mortality remains controversial. This study aimed to investigate the 'weekend-effect' on outcomes using a multicentre dataset of patients with ST elevation myocardial infarction (STEMI) and non-ST elevation myocardial infarction/unstable angina (NSTEMI/UA). DESIGN: This retrospective observational study used propensity score (PS) stratification to adjust estimates of weekend effect for observed confounding...
September 29, 2017: BMJ Open
https://www.readbyqxmd.com/read/28952883/stand-by-your-stroop-standing-up-enhances-selective-attention-and-cognitive-control
#12
David Rosenbaum, Yaniv Mama, Daniel Algom
No abstract text is available yet for this article.
September 1, 2017: Psychological Science
https://www.readbyqxmd.com/read/28948047/electrochemical-sensor-based-on-low-silica-x-zeolite-modified-carbon-paste-for-carbaryl-determination
#13
Fatima Ezzahra Salih, Brahim Achiou, Mohamed Ouammou, Jamal Bennazha, Aicha Ouarzane, Saad Alami Younssi, Mama El Rhazi
A new and simple approach for carbaryl determination in natural sample was proposed using Low Silica X (LSX) zeolite modified carbon paste electrode. LSX zeolite with a porous structure was incorporated into carbon paste electrode in the appropriate portion. The prepared electrode was then characterized using scanning electron microscopy, cyclic voltammetry and electrochemical impedance spectroscopy. Various experimental parameters as the zeolite amounts, pH, accumulation time, and differential pulse voltammetric parameters were optimized...
November 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/28945130/pharmacokinetics-and-selected-pharmacodynamics-of-trazodone-following-intravenous-and-oral-administration-to-horses-undergoing-fitness-training
#14
Heather K Knych, Khursheed R Mama, Eugene P Steffey, Scott D Stanley, Philip H Kass
OBJECTIVE To measure concentrations of trazodone and its major metabolite in plasma and urine after administration to healthy horses and concurrently assess selected physiologic and behavioral effects of the drug. ANIMALS 11 Thoroughbred horses enrolled in a fitness training program. PROCEDURES In a pilot investigation, 4 horses received trazodone IV (n = 2) or orally (2) to select a dose for the full study; 1 horse received a vehicle control treatment IV. For the full study, trazodone was initially administered IV (1...
October 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28943379/investigating-heterogeneity-of-effects-and-associations-using-interaction-terms
#15
Evangelos Kontopantelis, Matthew Sperrin, Mamas Mamas, Iain Buchan
Effect heterogeneity, the variability of an association or exposure across subgroups, usually warrants further investigation. The aim of this deeper analysis is to identify effect modifiers (or moderators) and quantify their relationship with the exposure. We explain why it is better to harness interaction effects within a single analytic model than to use separate models to analyse each subgroup. Using examples, we demonstrate a practical approach to modelling and interpretation with interaction terms from various measurement scales (categorical by categorical; categorical by continuous; and continuous by continuous)...
September 21, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28927187/impact-of-co-morbid-burden-on-mortality-in-patients-with-coronary-heart-disease-heart-failure-and-cerebrovascular-accident-a-systematic-review-and-meta-analysis
#16
Muhammad Rashid, Chun Shing Kwok, Chris P Gale, Patrick Doherty, Ivan Olier, Matthew Sperrin, Evangelos Kontopantelis, George Peat, Mamas A Mamas
Aims: We sought to investigate the prognostic impact of co-morbid burden as defined by the Charlson Co-morbidity Index (CCI) in patients with a range of prevalent cardiovascular diseases. Methods and results: We searched MEDLINE and EMBASE to identify studies that evaluated the impact of CCI on mortality in patients with cardiovascular disease. A random-effects meta-analysis was undertaken to evaluate the impact of CCI on mortality in patients with coronary heart disease (CHD), heart failure (HF), and cerebrovascular accident (CVA)...
January 1, 2017: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/28923695/the-effect-of-pre-procedure-sublingual-nitroglycerin-on-radial-artery-diameter-and-allen-s-test-outcome-relevance-to-transradial-catheterization
#17
Aun-Yeong Chong, Ted Lo, Sudhakar George, Karim Ratib, Mamas Mamas, James Nolan
BACKGROUND: The radial artery is increasingly used for cardiac procedures, but is a relatively small vessel that is prone to spasm when instrumented. Intra-arterial nitroglycerine has been shown to reduce radial spasm but first requires arterial access. We investigated the effect of pre-procedure sublingual nitroglycerin (NTG) on the diameter of the radial artery in a large cohort of patients. METHODS: 305 subjects underwent ultrasound measurement of their radial and ulnar arteries in both arms before and after the administration of 800μg of sublingual NTG...
July 29, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28917753/nuclear-forensics-investigation-of-morphological-signatures-in-the-thermal-decomposition-of-uranyl-peroxide
#18
Ian J Schwerdt, Adam Olsen, Robert Lusk, Sean Heffernan, Michael Klosterman, Bryce Collins, Sean Martinson, Trenton Kirkham, Luther W McDonald
The analytical techniques typically utilized in a nuclear forensic investigation often provide limited information regarding the process history and production conditions of interdicted nuclear material. In this study, scanning electron microscopy (SEM) analysis of the surface morphology of amorphous-UO3 samples calcined at 250, 300, 350, 400, and 450°C from uranyl peroxide was performed to determine if the morphology was indicative of the synthesis route and thermal history for the samples. Thermogravimetic analysis-mass spectrometry (TGA-MS) and differential scanning calorimetry (DSC) were used to correlate transitions in the calcined material to morphological transformations...
January 1, 2018: Talanta
https://www.readbyqxmd.com/read/28916604/coronary-perforation-complicating-percutaneous-coronary-intervention-in-patients-with-a-history-of-coronary-artery-bypass-surgery-an-analysis-of-309-perforation-cases-from-the-british-cardiovascular-intervention-society-database
#19
Tim Kinnaird, Richard Anderson, Nick Ossei-Gerning, James Cockburn, Alex Sirker, Peter Ludman, Mark de Belder, Thomas W Johnson, Samuel Copt, Azfar Zaman, Mamas A Mamas
BACKGROUND: The evidence base for coronary perforation (CP) occurring during percutaneous coronary intervention in patients with a history of coronary artery bypass surgery (PCI-CABG) is limited and the long-term effects unclear. Using a national PCI database, the incidence, predictors, and outcomes of CP during PCI-CABG were defined. METHODS AND RESULTS: Data were analyzed on all PCI-CABG procedures performed in England and Wales between 2005 and 2013. Multivariate logistic regressions and propensity scores were used to identify predictors of CP and its association with outcomes...
September 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28885419/competency-based-objectives-in-global-underserved-women-s-health-for-medical-trainees
#20
Chi Chiung Grace Chen, Anne Dougherty, Sara Whetstone, Saifuddin T Mama, Margaret Larkins-Pettigrew, Susan P Raine, Amy M Autry
The Association of Professors of Gynecology and Obstetrics Committee on Global Health developed an inclusive definition of global women's health and competency-based objectives that reflected work internationally, as well as with U.S. vulnerable and underserved populations, such as refugee and immigrant populations or those who would otherwise have compromised access to health care. The knowledge, skill, and attitude-based competencies required to fulfill each learning objective were mapped to the Accreditation Council for Graduate Medical Education Outcomes Project's educational domains and the Consortium of Universities for Global Health competency domains...
October 2017: Obstetrics and Gynecology
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