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https://www.readbyqxmd.com/read/28095413/one-month-global-longitudinal-strain-identifies-patients-who-will-develop-pacing-induced-left-ventricular-dysfunction-over-time-the-pacing-and-ventricular-dysfunction-pavd-study
#1
Fozia Zahir Ahmed, Manish Motwani, Colin Cunnington, Chun Shing Kwok, Catherine Fullwood, Delvac Oceandy, Alan Fitchet, Grahame Kevin Goode, Matthew Luckie, Amir Masood Zaidi, Rajdeep Khattar, Mamas Andreas Mamas
BACKGROUND: Predicting which individuals will have a decline in left ventricular (LV) function after pacemaker implantation remains an important challenge. We investigated whether LV global longitudinal strain (GLS), measured by 2D speckle tracking strain echocardiography, can identify patients at risk of pacing-induced left ventricular dysfunction (PIVD) or pacing-induced cardiomyopathy (PICMP). METHODS: Fifty-five patients with atrioventricular block and preserved LV function underwent dual-chamber pacemaker implantation and were followed with serial transthoracic echocardiography for 12 months for the development of PIVD (defined as a reduction in LV ejection fraction (LVEF) ≥5 percentage points at 12 months) or PICMP (reduction in LVEF to <45%)...
2017: PloS One
https://www.readbyqxmd.com/read/28087142/ultrastructural-characteristics-of-the-mature-spermatozoon-of-the-digenean-sclerodistomum-italicum-stossich-1893-hemiuroidea-sclerodistomidae-intestinal-parasite-of-hypocanthus-amia-teleostei-carangidae
#2
Papa Ibnou Ndiaye, Yann Quilichini, Adji Mama Marigo, Cheikh Tidiane Bâ, Vasyl V Tkach, Bernard Marchand
The mature spermatozoon of Sclerodistomum italicum is filiform, tapered at both ends and shows the following features: 2 axonemes of the 9+"1" pattern of the Trepaxonemata, mitochondrion, nucleus and parallel cortical microtubules. The specific features of the spermatozoon of S. italicum include the simultaneous presence of two types of extramembranous ornamentations, the presence of short cortical microtubules in the anterior part of the spermatozoon and the presence of only one bundle of cortical microtubules in the median part of the spermatozoon...
December 30, 2016: Tissue & Cell
https://www.readbyqxmd.com/read/28086814/intestinal-helminth-co-infection-and-associated-factors-among-tuberculosis-patients-in-arba-minch-ethiopia
#3
Getaneh Alemu, Mohammedaman Mama
BACKGROUND: Helminths affect the outcome of tuberculosis by shifting cell mediated immune response to humoral and by total suppression of the host immune system. On the reverse, Mycobacterium infection favors immune escape of helminths. Therefore assessing helminth co-infection rate and predisposing factors in tuberculosis patients is mandatory to set strategies for better case management. METHODS: Facility based cross-sectional study was conducted in Arba Minch to assess the prevalence and associated factors of intestinal helminths among pulmonary tuberculosis patients from January to August, 2016...
January 13, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28074617/soft-drink-intake-and-the-risk-of-metabolic-syndrome-a%C3%A2-systematic-review-and-meta-analysis
#4
REVIEW
Aditya Narain, Chun Shing Kwok, Mamas A Mamas
BACKGROUND: It is unclear whether consumption of sugar- or artificially sweetened beverages is independently associated with the development of metabolic syndrome. A systematic review and meta-analysis was performed to evaluate whether soft drink consumption is associated with the development of metabolic syndrome. METHODS: Medline and EMBASE were searched in November 2015 for studies which considered soft drink (sugar-sweetened beverage [SSB] and artificially sweetened beverage [ASB]) intake and risk of metabolic syndrome...
January 10, 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28056835/clinical-prediction-in-defined-populations-a-simulation-study-investigating-when-and-how-to-aggregate-existing-models
#5
Glen P Martin, Mamas A Mamas, Niels Peek, Iain Buchan, Matthew Sperrin
BACKGROUND: Clinical prediction models (CPMs) are increasingly deployed to support healthcare decisions but they are derived inconsistently, in part due to limited data. An emerging alternative is to aggregate existing CPMs developed for similar settings and outcomes. This simulation study aimed to investigate the impact of between-population-heterogeneity and sample size on aggregating existing CPMs in a defined population, compared with developing a model de novo. METHODS: Simulations were designed to mimic a scenario in which multiple CPMs for a binary outcome had been derived in distinct, heterogeneous populations, with potentially different predictors available in each...
January 6, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28035491/cancer-event-rate-and-mortality-with-thienopyridines-a-systematic-review-and-meta-analysis
#6
REVIEW
Rafail Angelos Kotronias, Chun Shing Kwok, Chun Wai Wong, Tim Kinnaird, Azfar Zaman, Mamas A Mamas
INTRODUCTION: Thienopyridines are a class of antiplatelet drugs widely used in cardiovascular disease prevention and treatment. A recent concern has come to light regarding the safety of thienopyridines because of the possible risk of malignancy. We therefore performed a systematic review and meta-analysis to evaluate the association between thienopyridine exposure and malignancy. METHODS: We searched the MEDLINE and EMBASE databases in March 2016 for studies that evaluated incident cancer and cancer mortality with and without exposure to thienopyridines...
December 29, 2016: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/28033738/the-production-effect-in-adults-with-dysarthria-improving-long-term-verbal-memory-by-vocal-production
#7
Michal Icht, Orly Bergerzon-Biton, Yaniv Mama
People show better memory for words read aloud relative to words read silently, the Production Effect (PE). Vocalisation at study makes the produced (aloud) words more distinct than the non-produced (silent) words, hence more memorable. Such encoding distinctiveness is related to the additional processing of aloud words that is later used during retrieval. This study investigated the PE in dysarthric adults, characterised by speech production difficulties. Their memory performance (recognition) was compared to a group of healthy adults...
December 29, 2016: Neuropsychological Rehabilitation
https://www.readbyqxmd.com/read/28029209/mortality-after-percutaneous-coronary-revascularization-prior-cardiovascular-risk-factor-control-and-improved-outcomes-in-patients-with-diabetes-mellitus
#8
Awsan Noman, Karthik Balasubramaniam, M Hafez A Alhous, Kelvin Lee, Peter Jesudason, Muhammad Rashid, Mamas A Mamas, Azfar G Zaman
OBJECTIVES: To assess the mortality in patients with diabetes mellitus (DM) following percutaneous coronary intervention (PCI) according to their insulin requirement and PCI setting (elective, urgent, and emergency). BACKGROUND: DM is a major risk factor to develop coronary artery disease (CAD). It is unclear if meticulous glycemic control and aggressive risk factor management in patients with DM has improved outcomes following PCI. METHODS: Retrospective analysis of prospectively collected data on 9,224 patients treated with PCI at a regional tertiary center between 2008 and 2011...
December 28, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28006892/a-novel-taqmama-assay-for-allelic-discrimination-of-immunoproteasome-subunit-psmb8-in-pediatric-patients
#9
Massimiliano Bergallo, Paola Montanari, Elisa Loiacono, Ilaria Galliano
BACKGROUND: A more recent improvement in MAMA was made when the allele selectivity of MAMA primers was combined with the 5' fluorogenic exonuclease (TaqMan) assay. This strategy referred to as TaqMAMA. METHODS: A SNP rs9357155 at the PSMB8 locus (GenBank access number NM_148919.3.) on chromosome 6 showing a C/T transition in position 32842071, has been chosen as model in this study. RESULTS: Tested assays have provided to be linear over two log10 of magnitude and have efficiencies close to the average of 80...
December 22, 2016: Minerva Pediatrica
https://www.readbyqxmd.com/read/28005548/cost-sharing-rates-increase-during-deep-recession-preliminary-data-from-greece
#10
Athanasios Gouvalas, Michael Igoumenidis, Mamas Theodorou, Kostas Athanasakis
BACKGROUND: Measures taken over the past four years in Greece to reduce pharmaceutical expenditure have led to significant price reductions for medicines, but have also changed patient cost-sharing rates for prescription drugs. This study attempts to capture the resulting increase in patients' out-of-pocket (OOP) expenses for prescription drugs during the 2011-2014 period. METHODS: The authors conducted a retrospective review of financial data derived from 39 883 prescriptions, dispensed at three randomly chosen pharmacies located in Lamia, central Greece...
May 28, 2016: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/27986755/impact-of-incomplete-percutaneous-revascularization-in-patients-with-multivessel-coronary-artery-disease-a-systematic-review-and-meta-analysis
#11
Vinayak Nagaraja, Sze-Yuan Ooi, James Nolan, Adrian Large, Mark De Belder, Peter Ludman, Rodrigo Bagur, Nick Curzen, Takashi Matsukage, Fuminobu Yoshimachi, Chun Shing Kwok, Colin Berry, Mamas A Mamas
BACKGROUND: Up to half of patients undergoing percutaneous coronary intervention have multivessel coronary artery disease (MVD) with conflicting data regarding optimal revascularization strategy in such patients. This paper assesses the evidence for complete revascularization (CR) versus incomplete revascularization in patients undergoing percutaneous coronary intervention, and its prognostic impact using meta-analysis. METHODS AND RESULTS: A search of PubMed, EMBASE, MEDLINE, Current Contents Connect, Google Scholar, Cochrane library, Science Direct, and Web of Science was conducted to identify the association of CR in patients with multivessel coronary artery disease undergoing percutaneous coronary intervention with major adverse cardiac events and mortality...
December 16, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27969692/tct-342-incomplete-revascularisation-and-12-month-mortality-in-octogenarians-undergoing-percutaneous-coronary-intervention-support-for-a-conservative-des-driven-strategy
#12
Silvio Fedele, Fairoz Belary Abdul, Nick Ossei-Gerning, Anirban Choudhury, James Cockburn, Richard Anthony Anderson, Mamas Mamas, Tim Kinnaird
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969678/tct-333-percutaneous-coronary-intervention-in-octogenarians-a-risk-scoring-system-to-predict-outcomes-in-the-elderly-on-behalf-of-the-british-cardiovascular-intervention-society-bcis-and-the-national-institute-for-cardiovascular-outcomes-research-nicor
#13
James Cockburn, David Hildick-Smith, Nick Curzen, Peter Ludman, Mamas Mamas, Mark de Belder, Adam De Belder
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969591/tct-252-the-incidence-determinants-and-outcomes-of-coronary-perforation-during-percutaneous-coronary-intervention-in-the-united-kingdom-between-2006-2013-an-analysis-of-527-121-cases-from-the-british-cardiovascular-intervention-society-database
#14
Tim Kinnaird, Chun Shing Kwok, Evan Kontopantelis, Ossei-Gerning Nick, Peter Ludman, Mark de Belder, Richard Anthony Anderson, Mamas Mamas
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27958761/delay-discounting-risk-taking-and-rejection-sensitivity-among-individuals-with-internet-and-video-gaming-disorders
#15
Aviv Weinstein, Hodaya Ben Abu, Ayelet Timor, Yaniv Mama
Background and aims There is a previous evidence for impulsivity in individuals with Internet and Video Gaming Disorders. The aim of this study was to examine whether Internet and video game addictions are associated with experiential delay discounting, risk-taking, and sensitivity to social rejection using computerized tasks and questionnaires. Methods Twenty participants (mean age 24, SD = 1.55) with high score on the Problematic Online Gaming Questionnaire (POGQ) were compared with 20 participants (mean age 24...
December 2016: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/27871241/prevalence-antimicrobial-susceptibility-patterns-and-associated-risk-factors-of-shigella-and-salmonella-among-food-handlers-in-arba-minch-university-south-ethiopia
#16
Mohammedaman Mama, Getaneh Alemu
BACKGROUND: The availability of safe food improves health of the people that contributes to productivity and provides an effective platform for development and poverty alleviation. On the other hand, unsafe food handling and processing can serve as a vehicle for the transmission of a variety of disease causing agents. The risk of food getting contaminated depends largely on the health status of the food handlers, their personal hygiene, knowledge and practice of food hygiene. Food borne diseases are therefore a public health problem in developed and developing countries which is also true for Ethiopia...
November 21, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27866164/relationship-between-anemia-and-mortality-outcomes-in-a-national-acute-coronary-syndrome-cohort-insights-from-the-uk-myocardial-ischemia-national-audit-project-registry
#17
Mamas A Mamas, Chun Shing Kwok, Evangelos Kontopantelis, Anthony A Fryer, Iain Buchan, Max O Bachmann, M Justin Zaman, Phyo K Myint
BACKGROUND: We aim to determine the prevalence of anemia in acute coronary syndrome (ACS) patients and compare their clinical characteristics, management, and clinical outcomes to those without anemia in an unselected national ACS cohort. METHODS AND RESULTS: The Myocardial Ischemia National Audit Project (MINAP) registry collects data on all adults admitted to hospital trusts in England and Wales with diagnosis of an ACS. We conducted a retrospective cohort study by analyzing patients in this registry between January 2006 and December 2010 and followed them up until August 2011...
November 19, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27863352/ultrafiltration-for-acute-decompensated-cardiac-failure-a-systematic-review-and-meta-analysis
#18
Chun Shing Kwok, Chun Wai Wong, Claire A Rushton, Fozia Ahmed, Colin Cunnington, Simon J Davies, Ashish Patwala, Mamas A Mamas, Duwarakan Satchithananda
BACKGROUND: Ultrafiltration is a method used to achieve diuresis in acute decompensated heart failure (ADHF) when there is diuretic resistance, but its efficacy in other settings is unclear. We therefore conducted a systematic review and meta-analysis to evaluate the use of ultrafiltration in ADHF. METHODS: We searched MEDLINE and EMBASE for studies that evaluated outcomes following filtration compared to diuretic therapy in ADHF. The outcomes of interest were body weight change, change in renal function, length of stay, frequency of rehospitalization, mortality and dependence on dialysis...
February 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/27855772/mandela-s-generation-99-years-old-and-still-thriving-and-surviving-this-is-the-story-of-mama-matlala
#19
Jocelyn Anstey Watkins
No abstract text is available yet for this article.
2016: Global Health Action
https://www.readbyqxmd.com/read/27855663/pre-pregnancy-community-based-intervention-for-couples-in-malaysia-application-of-intervention-mapping
#20
Shane A Norris, Julius Cheah Chee Ho, Aswir Abd Rashed, Vibeke Vinding, Jutta K H Skau, Regien Biesma, Jens Aagaard-Hansen, Mark Hanson, Priya Matzen
BACKGROUND: Malaysia is experiencing a nutrition transition with burgeoning obesity, particularly in women, and a growing prevalence of non-communicable disease. These health burdens have severe implications not only for adult health but also across generations. Pre-conception health promotion could address the intergenerational risk of metabolic disease. This paper describes the development of the "Jom Mama" intervention using Intervention Mapping (IM). The Jom Mama intervention aims to improve the health of young adult couples in Malaysia prior to conception...
November 17, 2016: BMC Public Health
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