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Surgery for movement disorders

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https://www.readbyqxmd.com/read/29473781/prediction-of-depression-and-anxiety-via-patient-assessed-tremor-severity-not-physician-reported-motor-symptom-severity-in-patients-with-parkinson-s-disease-or-essential-tremor-who-have-undergone-deep-brain-stimulation
#1
Rebecca L Achey, Erin Yamamoto, Daniel Sexton, Christine Hammer, Bryan S Lee, Robert S Butler, Nicolas R Thompson, Sean J Nagel, Andre G Machado, Darlene A Lobel
OBJECTIVE Deep brain stimulation (DBS) is an effective therapy for movement disorders such as idiopathic Parkinson's disease (PD) and essential tremor (ET). However, some patients who demonstrate benefit on objective motor function tests do not experience postoperative improvement in depression or anxiety, 2 important components of quality of life (QOL). Thus, to examine other possible explanations for the lack of a post-DBS correlation between improved objective motor function and decreased depression or anxiety, the authors investigated whether patient perceptions of motor symptom severity might contribute to disease-associated depression and anxiety...
February 23, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29473778/assessment-of-the-praxis-circuit-in-glioma-surgery-to-reduce-the-incidence-of-postoperative-and-long-term-apraxia-a-new-intraoperative-test
#2
Marco Rossi, Luca Fornia, Guglielmo Puglisi, Antonella Leonetti, Gianmarco Zuccon, Enrica Fava, Daniela Milani, Alessandra Casarotti, Marco Riva, Federico Pessina, Gabriella Cerri, Lorenzo Bello
OBJECTIVE Apraxia is a cognitive-motor deficit affecting the execution of skilled movements, termed praxis gestures, in the absence of primary sensory or motor disorders. In patients affected by stroke, apraxia is associated with lesions of the lateral parietofrontal stream, connecting the posterior parietal areas with the ventrolateral premotor area and subserving sensory-motor integration for the hand movements. In the neurosurgical literature to date, there are few reports regarding the incidence of apraxia after glioma surgery...
February 23, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29442369/spinal-cord-stimulation-therapy-for-gait-dysfunction-in-advanced-parkinson-s-disease-patients
#3
Olivia Samotus, Andrew Parrent, Mandar Jog
BACKGROUND: Benefits of dopaminergic therapy and deep brain stimulation are limited and unpredictable for axial symptoms in Parkinson's disease. Dorsal spinal cord stimulation may be a new therapeutic approach. The objective of this study was to investigate the therapeutic effect of spinal cord stimulation on gait including freezing of gait in advanced PD patients. METHODS: Five male PD participants with significant gait disturbances and freezing of gait underwent midthoracic spinal cord stimulation...
February 14, 2018: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/29427344/directional-communication-during-movement-execution-interferes-with-tremor-in-parkinson-s-disease
#4
Georgios Naros, Florian Grimm, Daniel Weiss, Alireza Gharabaghi
BACKGROUND: Both the cerebello-thalamo-cortical circuit and the basal ganglia/cortical motor loop have been postulated to be generators of tremor in PD. The recent suggestion that the basal ganglia trigger tremor episodes and the cerebello-thalamo-cortical circuitry modulates tremor amplitude combines both competing hypotheses. However, the role of the STN in tremor generation and the impact of proprioceptive feedback on tremor suppression during voluntary movements have not been considered in this model yet...
February 2018: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/29423886/paraplegic-patients-how-to-measure-balance-and-what-is-normal-or-functional
#5
REVIEW
Kaku Barkoh, Joshua W Lucas, Larry Lee, Patrick C Hsieh, Jeffrey C Wang, Kevin Rolfe
PURPOSE: To review the current understanding and data of sagittal balance and alignment considerations in paraplegic patients. METHODS: A PubMed literature search was conducted to identify all relevant articles relating to sagittal alignment and sagittal balance considerations in paraplegic and spinal cord injury patients. RESULTS: While there are numerous studies and publications on sagittal balance in the ambulatory patient with spinal deformity or complex spine disorders, there is paucity of the literature on "normal" sagittal balance in the paraplegic patients...
February 8, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29414403/postoperative-rehabilitation-after-deep-brain-stimulation-surgery-for-movement-disorders
#6
REVIEW
Niels Allert, Binith Cheeran, Günther Deuschl, Michael T Barbe, Ilona Csoti, Markus Ebke, Martin Glaser, Jun-Suk Kang, Stefan Kelm, Paul Krack, Julia Kroth, Ulrich Jobst, Markus Leisse, Antonio Oliviero, Peter Nikolaus Nolte, Johanna Quick-Weller, Martin Strothjohann, Gertrúd Tamás, Michael Werner, Muthuraman Muthuraman, Jens Volkmann, Alfonso Fasano, Sergiu Groppa
Deep brain stimulation (DBS) is a highly efficient, evidence-based therapy for a set of neurological and psychiatric conditions and especially movement disorders such as Parkinson's disease, essential tremor and dystonia. Recent developments have improved the DBS technology. However, no unequivocal algorithms for an optimized postoperative care exist so far. The aim of this review is to provide a synopsis of the current clinical practice and to propose guidelines for postoperative and rehabilitative care of patients who undergo DBS...
January 10, 2018: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29396058/stuttering-in-parkinson-s-disease-after-deep-brain-stimulation-a-note-on-dystonia-and-low-frequency-stimulation
#7
Marcelo D Mendonça, Raquel Barbosa, Alexandra Seromenho-Santos, Carla Reizinho, Paulo Bugalho
Stuttering, a speech fluency disorder, is a rare complication of Deep Brain Stimulation (DBS) in Parkinson's Disease (PD). We report a 61 years-old patient with PD, afflicted by severe On and Off dystonia, treated with Subthalamic Nucleus DBS that developed post-DBS stuttering while on 130 Hz stimulation. Stuttering reduction was noted when frequency was changed to 80 Hz, but the previously observed dystonia improvement was lost. There are no reports in literature on patients developing stuttering with low-frequency stimulation...
January 26, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29385927/preliminary-experience-with-a-transcranial-magnetic-resonance-guided-focused-ultrasound-surgery-system-integrated-with-a-1-5-t-mri-unit-in-a-series-of-patients-with-essential-tremor-and-parkinson-s-disease
#8
Domenico Gerardo Iacopino, Cesare Gagliardo, Antonella Giugno, Giuseppe Roberto Giammalva, Alessandro Napoli, Rosario Maugeri, Francesca Graziano, Francesca Valentino, Giuseppe Cosentino, Marco D'Amelio, Tommaso Vincenzo Bartolotta, Carlo Catalano, Brigida Fierro, Massimo Midiri, Roberto Lagalla
OBJECTIVE Transcranial magnetic resonance-guided focused ultrasound surgery (tcMRgFUS) is one of the emerging noninvasive technologies for the treatment of neurological disorders such as essential tremor (ET), idiopathic asymmetrical tremor-dominant Parkinson's disease (PD), and neuropathic pain. In this clinical series the authors present the preliminary results achieved with the world's first tcMRgFUS system integrated with a 1.5-T MRI unit. METHODS The authors describe the results of tcMRgFUS in a sample of patients with ET and with PD who underwent the procedure during the period from January 2015 to September 2017...
February 2018: Neurosurgical Focus
https://www.readbyqxmd.com/read/29362998/cancer-associated-retinopathy-after-surgery-for-breast-cancer-a-case-report-and-review-of-the-literature
#9
Mirei Kamei, Yutaka Fujitomi, Yoshiyuki Kondo, Toru Adachi, Kohei Shibata, Yohei Takumi, Miyuki Abe, Kenji Sugio
We herein report a 50-year-old Japanese woman with breast cancer who complained of blurred vision and central scotoma in her left eye on the 12th day after surgery. Subsequently, the sudden-onset binocular visual disorder progressed, and she was diagnosed with cancer-associated retinopathy (CAR) based on the clinical findings. Although her visual acuity temporarily improved following the start of adjuvant chemotherapy, reductions in her visual acuity progressed once again. After two courses of steroid pulse therapy initiated from the 59th day following the onset of CAR, although her visual field was still constricted, her binocular visual acuity improved from finger movement to 0...
January 23, 2018: Surgical Case Reports
https://www.readbyqxmd.com/read/29354738/inpatient-morbidity-after-spinal-deformity-surgery-in-patients-with-movement-disorders
#10
Rafael De la Garza Ramos, C Rory Goodwin, Amit Jain, Daniel Martinez-Ramirez, Isaac O Karikari, Daniel M Sciubba
Background: To investigate the inpatient perioperative morbidity rate of patients with movement disorders (MD) after spinal deformity surgery. Methods: The Nationwide Inpatient Sample database from 2002 to 2011 was queried to identify adult patients with MD who underwent spinal deformity surgery. Complication rates were compared between patients with MD and controls. A multiple logistic regression analysis was conducted to assess the effect of MD on outcome. Results: A total of 365 patients with MD (3...
December 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29332078/magnetic-resonance-guided-high-intensity-focused-ultrasound-for-treating-movement-disorders
#11
Young Goo Kim, Eun Jung Kweon, Won Seok Chang, Hyun Ho Jung, Jin Woo Chang
Transcranial magnetic resonance-guided focused ultrasound (MRgFUS) surgery has recently gained favor as a novel, noninvasive alternative to conventional neurosurgery. In contrast to traditional ablative interventions, transcranial MRgFUS surgery is entirely imaging-guided and uses continuous temperature measurements at the target and surrounding tissue taken in real-time. Unlike Gamma Knife radiosurgery, MRgFUS surgery can make a lesion immediately and does not use ionizing radiation. Moreover, since no metallic device is implanted, MR imaging-based diagnosis is not restricted throughout life...
2018: Progress in Neurological Surgery
https://www.readbyqxmd.com/read/29332075/patient-evaluation-and-selection-for-movement-disorders-surgery-the-changing-spectrum-of-indications
#12
Steffen Paschen, Günther Deuschl
This report summarizes the state-of-the-art and controversies around patient selection for deep brain stimulation (DBS) for various conditions. Parkinson's disease (PD): several class I studies have shown superiority of DBS over best medical treatment for advanced PD with fluctuations and further inclusion criteria. One class I study suggests that PD patients with early motor complications might gain more quality of life if operated within 3 years after the onset of fluctuations. The subthalamic nucleus (STN) is still the standard target...
2018: Progress in Neurological Surgery
https://www.readbyqxmd.com/read/29332072/medical-management-of-movement-disorders
#13
Marina Picillo, Renato P Munhoz
Pharmacological treatment is the cornerstone in the management of movement disorders. Although most available treatment options have no impact on the underlying process of each movement disorder, symptomatic therapies can significantly improve patient's quality of life and level of disability. Here, we review the current knowledge on clinical symptomatic management of Parkinson's disease (both early and advanced stages), essential tremor, dystonia, and chorea. Ideally, treatment should be carried out by specialists with reasonable experience in movement disorders, as it needs to be tailored for each patient depending on several appraisals, including but not limited to patients' needs, compliance issues, potential side effects, caregiver support, and presence of comorbidities...
2018: Progress in Neurological Surgery
https://www.readbyqxmd.com/read/29332069/the-history-of-movement-disorder-brain-surgery
#14
L Dade Lunsford, Ajay Niranjan
The first surgical procedures for abnormal movement disorders began in the 1930s, when surgeons first proposed ablative techniques of the caudate nucleus or transection of motor (pyramidal) pathways to reduce involuntary movements in patients with Parkinson's related tremor. During the 50-year interval between 1945 and 1995, the development of precise intracranial guiding devices, brain maps, and advanced imaging led to the refinement of appropriate deep brain targets affecting extrapyramidal pathways. Lesional surgery and subsequent neuroaugmentation using deep brain stimulation extended the role of deep brain surgery for a wider group of patients with tremor, rigidity, dyskinesia, and other involuntary movement disorders...
2018: Progress in Neurological Surgery
https://www.readbyqxmd.com/read/29316056/rechargeable-internal-pulse-generators-as-initial-neurostimulators-for-deep-brain-stimulation-in-patients-with-movement-disorders
#15
Martin Jakobs, Manja Kloß, Andreas Unterberg, Karl Kiening
INTRODUCTION: Rechargeable internal pulse generators (r-IPGs) for deep brain stimulation (DBS) promise a longer battery life and cost effectiveness compared to non-rechargeable IPGs. However, patients need to learn to check the battery capacity and perform the recharging process to ensure continuous therapy. METHODS: n = 35 consecutive adult patients with movement disorders that underwent DBS electrode placement with implantation of a r-IPG were assessed with a questionnaire...
January 8, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/29301132/optical-measurements-during-deep-brain-stimulation-lead-implantation-safety-aspects
#16
Peter Zsigmond, Simone Hemm-Ode, Karin Wårdell
BACKGROUND: Intracerebral hemorrhage (ICH) is the most feared complication in deep brain stimulation (DBS) surgery. The aim of the study was to evaluate patient safety and outcome using laser Doppler flowmetry (LDF) as guidance tool during DBS implantations. METHODS: An LDF probe adapted for the stereotactic system was used as guide for creation of the trajectory. The microcirculation along 83 preplanned trajectories was measured with the guide during DBS surgery for movement disorders...
January 5, 2018: Stereotactic and Functional Neurosurgery
https://www.readbyqxmd.com/read/29295486/adaptive-deep-brain-stimulation-adbs-for-tourette-syndrome
#17
Sara Marceglia, Manuela Rosa, Domenico Servello, Mauro Porta, Sergio Barbieri, Elena Moro, Alberto Priori
Deep brain stimulation (DBS) has emerged as a novel therapy for the treatment of several movement and neuropsychiatric disorders, and may also be suitable for the treatment of Tourette syndrome (TS). The main DBS targets used to date in patients with TS are located within the basal ganglia-thalamo-cortical circuit involved in the pathophysiology of this syndrome. They include the ventralis oralis/centromedian-parafascicular (Vo/CM-Pf) nucleus of the thalamus and the nucleus accumbens. Current DBS treatments deliver continuous electrical stimulation and are not designed to adapt to the patient's symptoms, thereby contributing to unwanted side effects...
December 23, 2017: Brain Sciences
https://www.readbyqxmd.com/read/29203153/focused-ultrasound-subthalamotomy-in-patients-with-asymmetric-parkinson-s-disease-a-pilot-study
#18
Raul Martínez-Fernández, Rafael Rodríguez-Rojas, Marta Del Álamo, Frida Hernández-Fernández, Jose A Pineda-Pardo, Michele Dileone, Fernando Alonso-Frech, Guglielmo Foffani, Ignacio Obeso, Carmen Gasca-Salas, Esther de Luis-Pastor, Lydia Vela, José A Obeso
BACKGROUND: Ablative neurosurgery has been used to treat Parkinson's disease for many decades. MRI-guided focused ultrasound allows focal lesions to be made in deep brain structures without skull incision. We investigated the safety and preliminary efficacy of unilateral subthalamotomy by focused ultrasound in Parkinson's disease. METHODS: This prospective, open-label pilot study was done at CINAC (Centro Integral de Neurociencias), University Hospital HM Puerta del Sur in Madrid, Spain...
December 1, 2017: Lancet Neurology
https://www.readbyqxmd.com/read/29201041/decoding-of-human-movements-based-on-deep-brain-local-field-potentials-using-ensemble-neural-networks
#19
Mohammad S Islam, Khondaker A Mamun, Hai Deng
Decoding neural activities related to voluntary and involuntary movements is fundamental to understanding human brain motor circuits and neuromotor disorders and can lead to the development of neuromotor prosthetic devices for neurorehabilitation. This study explores using recorded deep brain local field potentials (LFPs) for robust movement decoding of Parkinson's disease (PD) and Dystonia patients. The LFP data from voluntary movement activities such as left and right hand index finger clicking were recorded from patients who underwent surgeries for implantation of deep brain stimulation electrodes...
2017: Computational Intelligence and Neuroscience
https://www.readbyqxmd.com/read/29194808/the-changing-landscape-of-surgery-for-parkinson-s-disease
#20
REVIEW
Christopher S Lozano, Joseph Tam, Andres M Lozano
Neurosurgical interventions have been used to treat PD for over a century. We examined the changing landscape of surgery for PD to appraise the value of various procedures in the context of advances in our understanding and technology. We assessed the number of articles published on neurosurgical procedures for PD over time as an albeit imprecise surrogate for their usage level. We identified over 8,000 publications associated with PD surgery. Over half the publications were on DBS. The field of DBS for PD showed a rapid rise in articles, but is now in a steady state...
January 2018: Movement Disorders: Official Journal of the Movement Disorder Society
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