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https://www.readbyqxmd.com/read/27932281/nutcracker-syndrome-a-rare-cause-of-left-flank-pain-that-can-also-manifest-as-unexplained-pelvic-pain
#1
Jean-Marie Berthelot, Frédéric Douane, Yves Maugars, Eric Frampas
Nutcracker syndrome (NCS) is symptomatic unilateral renal venous hypertension due to compression of the left renal vein between the superior mesenteric artery and aorta (anterior NCS) or between the aorta and spine (posterior NCS). The left ovarian or spermatic vein empties into the left renal vein and is an additional site of venostasis in about half the cases of NCS. The presenting symptom of NCS in about half the cases is atypical left flank pain suggesting a disorder of the lower ribs or thoracolumbar spinal junction, particularly as the pain worsens with standing and increased lumbar lordosis...
December 5, 2016: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/27932204/total-renal-denervation-reduces-sympathoexcitation-to-different-target-organs-in-a-model-of-chronic-kidney-disease
#2
REVIEW
Glaucia L Veiga, Erika E Nishi, Heder F Estrela, Gisele S Lincevicius, Guiomar N Gomes, Alex Y Simões Sato, Ruy R Campos, Cássia T Bergamaschi
It is known that increased sympathetic nerve activity in chronic kidney disease (CKD) progressively worsens kidney function and hypertension. We tested the hypothesis that total renal denervation contributes to reduce sympathetic activation to different beds and improves renal function in 5/6 nephrectomy model of CKD in male Wistar rats. After eight weeks of 5/6 nephrectomy surgery there was an increase in mean arterial pressure (CKD 179±22mmHg, n=6 vs. control animals 108±9; p<0.05, n=6) with no changes in heart rate (HR)...
December 1, 2016: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/27932191/iga-nephropathy-clinicopathologic-study-following-the-oxford-classification-progression-peculiarities-and-gender-related-differences
#3
Živile Riispere, Arvydas Laurinavičius, Anne Kuudeberg, Elviira Seppet, Kristin Sepp, Madis Ilmoja, Merike Luman, Külli Kõlvald, Asta Auerbach, Mai Ots-Rosenberg
BACKGROUND AND AIM: Immunoglobulin A nephropathy (IgAN) is the most frequent glomerular disease worldwide and one of the main causes of chronic kidney disease. We aimed to investigate clinicopathological correlations in IgAN patients by gender. MATERIALS AND METHODS: The study was based on a retrospective analysis of renal biopsy data and clinical manifestations of the disease. Consecutive 73 biopsy-proven IgAN cases of male (62%) and female (38%) patients were investigated...
November 22, 2016: Medicina
https://www.readbyqxmd.com/read/27932153/a-heartbreaking-renal-transplantation-is-norepinephrine-the-culprit-to-blame
#4
M G Vailas, S Vernadakis, K Kakavia, I Paizis, J Bokos, J Boletis, G Zavos
INTRODUCTION: Takotsubo cardiomyopathy (TCM), also known as "broken heart syndrome," "apical ballooning syndrome," and "stress-induced cardiomyopathy," was first described in Japanese patients in 1990 by Sato et al. TCM is an increasingly recognized syndrome characterized by transient and reversible systolic dysfunction of the apical and middle segments of the left ventricle. This syndrome resembles acute myocardial infarction in the absence of evident coronary artery occlusion. Herein, we present a case of a 51-year-old male who underwent his second deceased-donor renal transplantation for end-stage-renal-disease due to a work-related accident...
November 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27932116/surgical-complications-in-en-bloc-renal-transplantation
#5
M A Moreno de la Higuera Díaz, N Calvo Romero, I Pérez-Flores, M Calvo Arévalo, B Rodríguez Cubillo, A Shabaka, V López de la Manzanara, Á Gómez Vegas, J Blázquez Izquierdo, A I Sánchez-Fructuoso
En bloc pediatric transplantation (EBPT) began with the aim of increasing the donor pool due to the existing high demand for donors. At its inception, it was considered a type of suboptimal transplantation due to its association with a high incidence of vascular, urologic, and immunologic complications. The main objective of this study was to update information on EBPT with the largest case series that exists on a worldwide scale. In a retrospective study, the results obtained from brain-dead donors (BDDs; n = 770) were compared to those of EBPT (n = 100) from January 1990 to December 2012...
November 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27931569/relationship-between-immediate-resistive-index-measurement-after-renal-transplantation-and-renal-allograft-outcomes
#6
B P Mwipatayi, A E Suthananthan, R Daniel, M Rahmatzadeh, S D Thomas, M Phillips, V Vijayan
BACKGROUND: The arterial resistive index, also referred to as the resistive index (RI) or Pourcelot Index, is a measure of pulsatile blood flow. Previous studies have demonstrated the usefulness of the RI as a predictor of allograft outcomes based on RI measurement in the later stages after transplantation. However, there is little evidence of the predictive value of "immediate" RI measurement within 24 hours after transplantation. METHODS: We performed a retrospective cohort study of 305 adult renal transplants carried out between 2003 and 2013...
December 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27931542/risk-profile-and-in-hospital-prognosis-in-elderly-patients-presenting-for-acute-st-elevation-myocardial-infarction-in-the-tunisian-context
#7
Walid Jomaa, Sonia Hamdi, Imen Ben Ali, Mohamed A Azaiez, Aymen El Hraiech, Khaldoun Ben Hamda, Faouzi Maatouk
OBJECTIVES: Little is known about the risk profile and in-hospital prognosis of elderly patients presenting for ST-elevation myocardial infarction (STEMI) in Tunisia. We sought to determine in-hospital prognosis of elderly patients with STEMI in a Tunisian center. METHODS: The study was carried out on a retrospective registry enrolling 1403 patients presenting with STEMI in a Tunisian center between January 1998 and January 2013. Patients ≥75 years old were considered elderly...
November 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27929441/aortic-stiffness-as-a-surrogate-endpoint-to-micro-and-macrovascular-complications-in-patients-with-type-2-diabetes
#8
REVIEW
Claudia R L Cardoso, Gil F Salles
Increased aortic stiffness has been recognized as a predictor of adverse cardiovascular outcomes in some clinical conditions, such as in patients with arterial hypertension and end-stage renal disease, in population-based samples and, more recently, in type 2 diabetic patients. Patients with type 2 diabetes have higher aortic stiffness than non-diabetic individuals, and increased aortic stiffness has been correlated to the presence of micro- and macrovascular chronic diabetic complications. We aimed to review the current knowledge on the relationships between aortic stiffness and diabetic complications, their possible underlying physiopathological mechanisms, and their potential applications to clinical type 2 diabetes management...
December 6, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27928837/prenatal-diagnosis-of-idiopathic-infantile-arterial-calcification-without-fetal-hydrops
#9
Yan Yi, Tong Tong, Tao Liu, Qi Lin, Yi Xiong, Jinfeng Xu
Idiopathic infantile arterial calcification (IIAC) is a rare autosomal recessive disease that is characterized by extensive calcification of the internal elastic lamina and intimal proliferation of large- and medium-sized arteries, including the aortic, coronary, pulmonary, and iliac arteries. Most reported cases of IIAC were diagnosed in the neonatal periods. Prenatal diagnosis of this condition is extremely rare and is usually made in the third trimester when fetuses had nonimmune hydrops together with aortic and pulmonary calcification...
December 8, 2016: Echocardiography
https://www.readbyqxmd.com/read/27928736/antiplatelet-agents-in-hemodialysis
#10
REVIEW
Massimiliano Migliori, Vincenzo Cantaluppi, Alessia Scatena, Vincenzo Panichi
Patients affected by cardiovascular disease (CVD) are treated with antiplatelet agents (AA) and/or anticoagulant drugs, which are fundamental in the management of stroke, coronary atherosclerotic disease, peripheral vascular disease and atrial fibrillation. CVD is the most important cause of death in chronic renal failure (CRF). Death rates from myocardial infarction (MI) and from all other cardiac causes exceed those for the general population. Incidence of MI in CRF is triple that in the general population...
December 8, 2016: Journal of Nephrology
https://www.readbyqxmd.com/read/27928449/severe-asymptomatic-coronary-obstruction-in-chronic-hemodialysed-patient-a-case-report
#11
Voiculeț C, Zara O, Văcăroiu I, Bogeanu C, Tiron T, Turcu F, Aron G, Ciocâlteu A
Introduction. Arterial stiffness and vascular calcifications are independent predictors of cardiovascular morbidity and mortality in the chronic kidney disease (CKD) stage 5D population. According to the guidelines, patients on renal replacement therapy represent a very high cardiovascular risk class. Case report. We report the case of a 67-year-old hypertensive male patient, known with CKD stage 5D on hemodialysis (three times per week), secondary bone mineral disease, admitted for progressive right leg pain...
October 2016: Journal of Medicine and Life
https://www.readbyqxmd.com/read/27928064/3d-printing-guiding-stent-graft-fenestration-a-novel-technique-for-fenestration-in-endovascular-aneurysm-repair
#12
Jianhua Huang, Gan Li, Wei Wang, Keming Wu, Tianming Le
OBJECTIVE: To describe a novel approach, 3D printing guiding stent graft fenestration, for fenestration during endovascular aneurysm repair for juxtarenal abdominal aortic aneurysm. METHODS: A 69-year-old male with juxtarenal abdominal aortic aneurysm underwent endovascular aneurysm repair with "off the label" fenestrated stent graft. To precisely locate the fenestration position, we reconstructed a 3D digital abdominal aortic aneurysm model and created a skin template covering this abdominal aortic aneurysm model...
December 6, 2016: Vascular
https://www.readbyqxmd.com/read/27927653/knockdown-of-add3-impairs-the-myogenic-response-of-renal-afferent-arterioles-and-middle-cerebral-arteries
#13
Fan Fan, Mallikarjuna R Pabbidi, Ying Ge, Longyang Li, Shaoxun Wang, Paige N Mims, Richard J Roman
We have reported that the myogenic response of the renal afferent arteriole (Af-art) and middle cerebral artery (MCA), and autoregulation of renal and cerebral blood flow are impaired in Fawn Hood Hypertensive (FHH) rats. Transfer of a region of chromosome 1 containing gamma-adducin (Add3) from Brown Norway rats rescues the vascular dysfunction and the development of renal disease. To examine whether Add3 is a viable candidate gene altering renal and cerebral hemodynamics in FHH rats, we knocked down the expression of Add3 in rat Af-art and MCA cultured for 36-hours using a 27-mer Dicer-substrate short interfering RNA (DsiRNA)...
December 7, 2016: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/27927650/cellular-transport-of-l-arginine-determines-renal-medullary-blood-flow-in-control-rats-but-not-in-diabetic-rats-despite-enhanced-cellular-uptake-capacity
#14
Patrik Persson, Angelica Fasching, Tom Teerlink, Peter Hansell, Fredrik Palm
Diabetes mellitus is associated with decreased nitric oxide bioavailability thereby affecting renal blood flow regulation. Previous reports have demonstrated that cellular uptake of L-arginine is rate limiting for nitric oxide production, and that plasma L-arginine concentration is decreased in diabetes. We therefore investigated if regional renal blood flow regulation is affected by cellular L-arginine uptake in streptozotocin-induced diabetic rats. Rats were anesthetized with thiobutabarbital and left kidney was exposed...
December 7, 2016: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/27927648/renin-angiotensin-system-transgenic-mouse-model-recapitulates-pathophysiology-similar-to-human-preeclampsia-with-renal-injury-that-may-be-mediated-through-vegf
#15
J Morgan Denney, Cynthia E Bird, Annette Gendron-Fitzpatrick, Emmanuel Sampene, Ian M Bird, Dinesh M Shah
Using a transgenic cross, we evaluated features of preeclampsia, renal injury and the sFlt1/VEGF changes. Transgenic hAGT and hREN, or wild type (WT) C57Bl/6 mice were cross-bred: ♀hAGT x ♂hREN for preeclampsia (PRE) model and ♀WT x ♂WT for pregnant controls (WTP). Samples were collected for plasma VEGF, sFlt1 and urine albumin. Blood pressures (BP) were monitored by telemetry. Vascular reactivity was investigated by wire myography. Kidneys and placenta were immunostained for sFlt1 and VEGF. Eleven PRE and 9 WTP mice were compared...
December 7, 2016: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/27927497/acute-renal-infarction-after-lateral-lumbar-interbody-spinal-fusion-for%C3%A2-kyphoscoliosis
#16
Sanjeev J Suratwala, MaryAnne Cronin, Katelyn Kondra, Vincent Leone
STUDY DESIGN: Case report. OBJECTIVES: Case report of acute renal infarction following lateral interbody fusion with posterior instrumentation for adult lumbar kyphoscoliosis. SUMMARY OF BACKGROUND DATA: This is the first reported renal infarction following minimally invasive lateral interbody fusion and posterior spinal instrumentation. METHODS: We report a case of acute renal infarction in a 72-year-old woman following direct lateral interbody fusion (DLIF) with percutaneous pedicle screw and rod fixation from L1 to L5 for correction of kyphoscoliosis...
September 2016: Spine Deformity
https://www.readbyqxmd.com/read/27927204/different-effect-of-hypercholesterolemia-on-mortality-in-hemodialysis-patients-based-on-coronary-artery-disease-or-myocardial-infarction
#17
Yi-Chun Lin, Yen-Chung Lin, Hsi-Hsien Chen, Tzen-Wen Chen, Chih-Cheng Hsu, Chiung-Chi Peng, Mai-Szu Wu
BACKGROUND: Studies on the association of total cholesterol (TC) levels and mortality in hemodialysis (HD) patients demonstrated conflicting results. The differenct effect of Hypercholesterolemia on HD patients based on the presence of myocardial infarction (MI) or coronary artery disease (CAD) is unknown. METHODS: We analyzed data from the Taiwan Renal Registry Data System (TWRDS) between 2005 and 2012. Patients were divided into MI/CAD or non-MI/CAD group. The primary outcome was three-year mortality...
December 8, 2016: Lipids in Health and Disease
https://www.readbyqxmd.com/read/27926465/freestyle-stentless-bioprosthesis-for-aortic-valve-therapy-17-year-clinical-results
#18
Juergen Ennker, Markus Meilwes, Joern Pons-Kuehnemann, Bernd Niemann, Philippe Grieshaber, Ina C Ennker, Andreas Boening
BACKGROUND: Aortic valve replacement with stentless bioprostheses has been shown to produce lower aortic gradients than stented bioprostheses, thus facilitating left ventricular mass regression and preventing heart failure. We sought to determine the long-term results of stentless biological aortic valve replacement over a 17-year follow-up. METHODS: Between 1996 and 2012, 2551 patients underwent isolated aortic valve replacement with a stentless prosthesis (Medtronic Freestyle) at a single center...
November 2016: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/27925869/endovascular-management-of-infected-iliofemoral-pseudoaneurysms-a-systematic-review
#19
Konstantinos G Moulakakis, Vangelis G Alexiou, George S Sfyroeras, John Kakisis, Andreas Lazaris, Spyridon N Vasdekis, Elias N Brountzos, George Geroulakos
We conducted a systematic review regarding the efficacy and outcome of endovascular treatment of infected iliofemoral arterial pseudoaneurysms with covered stents. 35 cases were identified, including 5 own. 22 pseudoaneurysms were located in the femoral area and 13 in the iliac vessels. The most commonly reported complaints were pulsatile groin mass (40 %), sepsis (37.1 %), active bleeding (31.4 %), and groin infection with purulent discharge (17.1 %). S. aureus (65.7 %) and Streptococcus species (22.9 %) were the most common microbes isolated...
December 7, 2016: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/27921152/proximal-occlusion-of-medium-sized-vessels-with-the-penumbra-occlusion-device-a-study-of-safety-and-efficacy
#20
E Jambon, F Petitpierre, V Brizzi, V Dubuisson, Y Le Bras, N Grenier, F Cornelis
PURPOSE: To retrospectively investigate the safety and efficacy of hybrid proximal coiling of various medium-sized vessels (4 to 8 mm) using the Penumbra Occlusion Device (POD). MATERIALS AND METHODS: From October 2014 to February 2016, 37 proximal embolizations were performed with PODs in 36 patients (mean age: 50.8, range: 10-86; 29 male, 7 female). Vessel occlusions were achieved under fluoroscopic guidance using a 2.7 French microcatheter. Among the 36 vessels targeted, 16 were splenic arteries, 11 renal arteries, 4 mesenteric arteries, 3 arteriovenous fistulae, 1 iliac artery, and 1 gonadal vein...
December 5, 2016: Cardiovascular and Interventional Radiology
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