Philipp Hemmann, Lisa Kloppenburg, Regina Breinbauer, Sabrina Ehnert, Gunnar Blumenstock, Marie K Reumann, Felix Erne, Johann Jazewitsch, Tobias Schwarz, Heiko Baumgartner, Tina Histing, Mika Rollmann, Andreas K Nüssler
Early and reliable detection of infection is vital for successful treatment. Serum markers such as C-reactive protein (CRP) and procalcitonin (PCT) are known to increase with a time lag. Azurocidin 1 (AZU1) has emerged as a promising marker for septic patients, but its diagnostic value in orthopedic and trauma patients remains unexplored. Between July 2020 and August 2023, all patients necessitating inpatient treatment for periprosthetic joint infection (PJI), peri-implant infection (II), soft tissue infection, chronic osteomyelitis, septic arthrodesis, bone non-union with and without infection were enrolled...
2024: EXCLI Journal