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https://www.readbyqxmd.com/read/29769133/electroacupuncture-for-abdominal-pain-relief-in-patients-with-acute-pancreatitis-study-protocol-for-a-randomized-controlled-trial
#1
Dong Kee Jang, Chan Yung Jung, Kyung Ho Kim, Jun Kyu Lee
BACKGROUND: Previous studies have shown that electroacupuncture (EA) reduces the severity of acute pancreatitis. However, the effect of EA for pain relief in patients with acute pancreatitis has not been evaluated yet. The purpose of this study was to prove the efficacy of EA for pain relief in patients with acute pancreatitis compared with conventional treatment. METHODS: This study is a randomized, controlled, three-arm, parallel-group, multi-center trial. Patients diagnosed with acute pancreatitis are enrolled and randomly assigned to EA 1, EA 2, or a control group in a 1:1:1 ratio...
May 16, 2018: Trials
https://www.readbyqxmd.com/read/29758357/pharmacopuncture-with-scolopendra-subspinipes-suppresses-mechanical-allodynia-in-oxaliplatin-induced-neuropathic-mice-and-potentiates-clonidine-induced-anti-allodynia-without-hypotension-or-motor-impairment
#2
Seo-Yeon Yoon, Jeong-Yun Lee, Dae-Hyun Roh, Seog Bae Oh
Chemotherapy-induced neuropathic pain is a common dose-limiting side effect of anticancer drugs but lacks an effective treatment strategy. Scolopendra subspinipes (SS) has been used in traditional medicine to treat chronic neuronal diseases. Moreover, pharmacopuncture with SS (SSP) produces potent analgesia in humans and experimental animals. In this study, we examined the effect of SSP into the ST36 acupoint on oxaliplatin-induced mechanical allodynia in mice. Acupoint treatment with SSP (0.5%/20 μL) significantly reduced mechanical allodynia produced by a single oxaliplatin injection (10 mg/kg, i...
May 11, 2018: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29735975/efficacy-of-acupuncture-therapy-for-chemotherapy-related-cognitive-impairment-in-breast-cancer-patients
#3
Taishan Tong, Chunqin Pei, Jun Chen, Qing Lv, Fuquan Zhang, Zaohuo Cheng
BACKGROUND Chemotherapy can cause adverse effects such as chemotherapy-related cognitive impairment (CRCI). In this prospective study, the efficacy of traditional Chinese medicine acupuncture therapy in relieving CRCI and its impact on serum brain-derived neurotrophic factor (BDNF) are evaluated. MATERIAL AND METHODS Eighty patients were randomly divided into a treatment group and a control group with 40 patients in each group. The treatment group was treated at the following acupuncture points: Baihui (DU20), Sishencong (EX-HN1), Shenting (DU24), Zusanli (ST36), Taixi (K13), Dazhong (K14), and Juegu (GB39)...
May 8, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29722303/harnessing-migraines-for-neural-regeneration
#4
REVIEW
Jonathan M Borkum
The success of naturalistic or therapeutic neuroregeneration likely depends on an internal milieu that facilitates the survival, proliferation, migration, and differentiation of stem cells and their assimilation into neural networks. Migraine attacks are an integrated sequence of physiological processes that may protect the brain from oxidative stress by releasing growth factors, suppressing apoptosis, stimulating neurogenesis, encouraging mitochondrial biogenesis, reducing the production of oxidants, and upregulating antioxidant defenses...
April 2018: Neural Regeneration Research
https://www.readbyqxmd.com/read/29712933/effect-of-electroacupuncture-on-99m-tc-sodium-pertechnetate-uptake-and-extracellular-fluid-free-molecules-in-the-stomach-in-acupoint-st36-and-st39
#5
Rui Gao, Shan Gao, Jinteng Feng, Hongying Cui, Yanchao Cui, Junke Fu, Guangjian Zhang
Electroacupuncture (EA) is a therapeutic modality in which the electrical stimulation is integrated with concepts of acupuncture to treat diseases. This study was designed to evaluate the connection between the electro-acupuncture induced increase in Na99m TcO4 uptake in the stomach wall, and the ionic molecule levels in the extracellular fluid in the acupoints. Wistar rats were treated by 2 or 100 Hz EA at Zusanli (ST 36) and Xiajuxu (ST 39) bilaterally for 60 minutes. The accumulation of Na99m TcO4 in the gastric wall and the free ions, including Ca2+ , K+ , Na+ , and Cl- , in the acupoints were measured every 60 minutes...
April 30, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29712659/carbapenem-resistant-hypervirulent-klebsiella-pneumoniae-of-sequence-type-36
#6
Yu Feng, Yang Lu, Zhihong Yao, Zhiyong Zong
ST36 Klebsiella pneumoniae distributes worldwide. We found that a ST36 K. pneumoniae clinical isolate was carbapenem resistant, carried bla KPC-2 , had mucoid regulator gene rmpA and exhibited high virulence. The findings suggest the emergence of carbapenem-resistant hypervirulent K. pneumoniae of ST36 and surveillance on carbapenem-resistant hypervirulent K. pneumoniae is required.
April 30, 2018: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29707031/mast-cells-and-nerve-signal-conduction-in-acupuncture
#7
Na Yin, Hongwei Yang, Wei Yao, Ying Xia, Guanghong Ding
Nerve and mast cells are densely distributed around acupoints in connective tissue. To explore the internal relations between them in acupuncture effect, we examined dorsal root potential (DRP) response to acupuncture at Zusanli (ST36) under sodium cromoglicate (DSCG, a mast cell stabilizer) intervention in anesthetized Sprague-Dawley (SD) rats. We used single unit nerve recording techniques to collect nerve signals from DRP afferent nerves for a 45-minute period that includes 4 stages, that is, base, drug absorption, acupuncture, and recovery stages...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29703040/electro-acupuncture-attenuates-inflammatory-responses-and-intraabdominal-pressure-in-septic-patients-a-randomized-controlled-trial
#8
Jian-Biao Meng, Yan-Na Jiao, Xiu-Juan Xu, Zhi-Zhen Lai, Geng Zhang, Chun-Lian Ji, Ma-Hong Hu
BACKGROUND: A pathological increase in intraabdominal pressure (IAP) and inflammatory responses have negative effects on splanchnic, respiratory, cardiovascular, renal, and neurological function in septic patients with intestinal dysfunction. Electro-acupuncture (EA) has been evidenced to have a bidirectional neuron-endocrine-immune system regulating effect in patients with intestinal dysfunction. The purpose of current study was to evaluate the effects of EA at "Zusanli" (ST36) and "Shangjuxu" (ST37) on inflammatory responses and IAP in septic patients with intestinal dysfunction manifested syndrome of obstruction of the bowels Qi...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29692183/effects-of-moxibustion-on-the-levels-of-insulin-like-growth-factor-1-a-pilot-study
#9
Jaung-Geng Lin, Shinn-Zong Lin, Lih-Hwa Lin, Chun-Chang Wu, Wan-Ting Tsai, Horng-Jyh Harn, Li-Hui Su, Wen-Yu Ho, Che-Jui Hsieh, Tsung-Jung Ho
Moxibustion () is a traditional Chinese medicine therapy performed using Artemisia argyii. Zusanli (, ST36) is an acupoint in the stomach meridian, long associated in ancient Chinese medical practices with the extension of life span when moxibustion is applied to it. The aim of this study was to investigate changes in insulin-like growth factor 1 (IGF-1) levels after application of moxibustion to ST36. Four healthy men and women participated in this 28-day trial and were randomly divided into 2 groups. Group A received moxibustion treatment from days 1 to 14, while group B received moxibustion treatment from days 15 to 28...
January 1, 2018: Cell Transplantation
https://www.readbyqxmd.com/read/29669795/electroacupuncture-reduces-hypothalamic-and-medullary-expression-of-orexins-and-their-receptors-in-a-rat-model-of-chronic-obstructive-pulmonary-disease
#10
Xin-Fang Zhang, Qin Qin, Wen-Ye Geng, Chuan-Wei Jiang, Yong Liu, Xiao-Li Liu, Jing Li, Zi-Bing Liu
OBJECTIVES: Decreased lung function in chronic obstructive pulmonary disease (COPD) is correlated with abnormal excitability of the respiratory centre where orexin neuropeptides from the hypothalamus are responsible for regulating respiration. We hypothesised that improvements in pulmonary function with electroacupuncture (EA) may be related to orexins in a rat model of COPD. METHODS: The COPD model was established by cigarette smoke exposure and lipopolysaccharide injection...
April 18, 2018: Acupuncture in Medicine: Journal of the British Medical Acupuncture Society
https://www.readbyqxmd.com/read/29660431/electroacupuncture-ameliorates-poloxamer-407-induced-hyperlipidemia-through-suppressing-hepatic-srebp-2-expression-in-rats
#11
Mijung Yeom, Jinhee Park, Bombi Lee, Hyang Sook Lee, Hi-Joon Park, Ran Won, Hyejung Lee, Dae-Hyun Hahm
AIMS: Acupuncture, particularly electroacupuncture (EA) has been shown to have the lipid-lowering effects, but not completely investigated. The present study was aimed to examine whether EA could attenuate poloxamer-407 (P-407)-induced hyperlipidemia in the rats and to investigate its potential mechanisms. MAIN METHODS: Rats received P-407 (0.4 g/kg, i.p.) to induce hyperlipidemia. EA was performed at ST36 and ST40 acupoints a total of three times with 12 h-interval starting 1 h before the P-407 injection at 0...
April 13, 2018: Life Sciences
https://www.readbyqxmd.com/read/29629296/effects-of-acupuncture-in-postmenopausal-women-with-prehypertension-or-stage-1-hypertension-study-protocol-for-a-prospective-comparative-interventional-cohort-study
#12
Bok-Nam Seo, Ji-Eun Park, Young-Eun Kim, Kyung-Won Kang, In-Chan Seol, Sun-Mi Choi
Background: Hypertension is a major cause of cardiovascular disease and associated mortality, and postmenopausal women are at a high risk of hypertension. We aim to investigate the hypotensive effect and safety of acupuncture, focusing on postmenopausal women with prehypertension and stage 1 hypertension. In addition, we aim to investigate whether the effect of acupuncture treatment differed, depending on Sasang Constitution and cold-heat pattern. Methods: This study is designed as an intervention cohort study...
March 2018: Integrative Medicine Research
https://www.readbyqxmd.com/read/29626523/expression-of-genes-in-primo-vasculature-floating-in-lymphatic-endothelium-under-lipopolysaccharide-and-acupuncture-electric-stimulation
#13
Jun-Young Shin, Jong-Ok Ji, Da-Woon Choi, Sang-Heon Choi, Jong-Gu Choi, Min-Suk Rho, Ji Yoon Lee, Sang-Suk Lee
It is known that the existence of primo vascular system (PVS) including the primo nodes and vessels. However, it is poorly understood the relevant genes in the PVS system both patho- and physiologic condition. Here, we first examined the gene expression in primo vessels (PV) floating in lymphatic endothelium by isolation of PVS and lymphatic vessels (LV) containing PVS. To investigate therapeutic effects, both PV and LV containing PVS were isolated after lipopolysaccharides (LPS) injection and acupuncture electric stimulation (AES) at two acupoints of Joksamni (ST36) and Hapgok (LI04) following LPS...
April 4, 2018: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/29623942/combined-acupuncture-and-huangdisan-treatment-affects-behavior-and-synaptophysin-levels-in-the-hippocampus-of-senescence-accelerated-mouse-prone-8-after-neural-stem-cell-transplantation
#14
Chun-Lei Zhou, Lan Zhao, Hui-Yan Shi, Jian-Wei Liu, Jiang-Wei Shi, Bo-Hong Kan, Zhen Li, Jian-Chun Yu, Jing-Xian Han
Sanjiao acupuncture and HuangDiSan can promote the proliferation, migration and differentiation of exogenous neural stem cells in senescence-accelerated mouse prone 8 (SAMP8) mice and can improve learning and memory impairment and behavioral function in dementia-model mice. Thus, we sought to determine whether Sanjiao acupuncture and HuangDiSan can elevate the effect of neural stem cell transplantation in Alzheimer's disease model mice. Sanjiao acupuncture was used to stimulate Danzhong (CV17), Zhongwan (CV12), Qihai (CV6), bilateral Xuehai (SP10) and bilateral Zusanli (ST36) 15 days before and after implantation of neural stem cells (5 × 105 ) into the hippocampal dentate gyrus of SAMP8 mice...
March 2018: Neural Regeneration Research
https://www.readbyqxmd.com/read/29623933/electroacupuncture-and-moxibustion-promote-regeneration-of-injured-sciatic-nerve-through-schwann-cell-proliferation-and-nerve-growth-factor-secretion
#15
Lin-Na Hu, Jin-Xin Tian, Wei Gao, Jing Zhu, Fang-Fang Mou, Xiao-Chun Ye, Yu-Pu Liu, Ping-Ping Lu, Shui-Jin Shao, Hai-Dong Guo
Using electroacupuncture and moxibustion to treat peripheral nerve injury is highly efficient with low side effects. However, the electroacupuncture- and moxibustion-based mechanisms underlying nerve repair are still unclear. Here, in vivo and in vitro experiments uncovered one mechanism through which electroacupuncture and moxibustion affect regeneration after peripheral nerve injury. We first established rat models of sciatic nerve injury using neurotomy. Rats were treated with electroacupuncture or moxibustion at acupoints Huantiao (GB30) and Zusanli (ST36)...
March 2018: Neural Regeneration Research
https://www.readbyqxmd.com/read/29608997/the-beneficial-effects-of-electroacupuncture-at-pc6-acupoints-neiguan-on-myocardial-ischemia-in-asic3-mice
#16
Ying-Wang, Wan-Shuang Zhao, Di Li, Ya-Han Xu, Meng-di Li, Jin Chen, Zhi-Jun Kou, Qi-Ge Wang, Yi-Guo Chen, Nsoa Dimitri Joseph
This study aims to investigate the possible mechanisms of electroacupuncture (EA) at PC6 to improve myocardial ischemia (MI) by regulating the cardiac transient outward potassium current channel (Ito). According to the random number table, the mice were divided into 6 groups of 6 mice each: control group, MI group, PC6, LU7 (Lieque-point), ST36 (Zusanli-point), and nonacupoint group. Mice in the control group were injected with saline (20mg/kg, 24 hours interval), and the other ASIC3 -/- mice were injected subcutaneously twice with isoproterenol (ISO) (20mg/kg, 24 hours interval)...
March 30, 2018: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/29599809/electroacupuncture-at-st36-increases-bone-marrow-derived-interstitial-cells-of-cajal-via-the-sdf-1-cxcr4-and-mscf-kit-etv1-pathways-in-the-stomach-of-diabetic-mice
#17
Jiao Zhao, Jing An, Shi Liu
Background: The loss of interstitial cells of Cajal (ICC) is observed in diabetic gastroparesis. Electroacupuncture (EA) maintains ICC networks, but the effects and mechanisms of EA on ICC of bone marrow derivation in the stomach have not been investigated. Methods: C57BL/6 mice were randomized into six groups: control, diabetic (DM), bone marrow transplantation (BMT) + DM, BMT + DM + sham EA (SEA), BMT + DM + low-frequency EA (LEA), and BMT + DM + high-frequency (HEA)...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29551908/mast-cell-deficiency-attenuates-acupuncture-analgesia-for-mechanical-pain-using-c-kit-gene-mutant-rats
#18
Xiang Cui, Kun Liu, Dandan Xu, Youyou Zhang, Xun He, Hao Liu, Xinyan Gao, Bing Zhu
Background: Acupuncture therapy plays a pivotal role in pain relief, and increasing evidence demonstrates that mast cells (MCs) may mediate acupuncture analgesia. The present study aims to investigate the role of MCs in acupuncture analgesia using c-kit gene mutant-induced MC-deficient rats. Materials and methods: WsRC-Ws/Ws rats and their wild-type (WT) littermates (WsRC-+/+) were used. The number of MCs in skin of ST36 area was compared in two rats after immunofluorescence labeling...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29550358/parameter-specific-analgesic-effects-of-electroacupuncture-mediated-by-degree-of-regulation-trpv1-and-p2x3-in-inflammatory-pain-in-rats
#19
J Q Fang, J Y Du, J F Fang, T Xiao, X Q Le, N F Pan, J Yu, B Y Liu
AIMS: Observing the parameter-specific anti-hyperalgesic effects of EA with different stimulation times and frequencies on painful hyperalgesia mediated by the level of TRPV1 and P2X3 expression in DRG after CFA injection. MAIN METHODS: The model was induced by the injection of CFA in each rat's right hind paw. EA treatment was applied to the bilateral ST36 and BL60. Paw withdrawal threshold (PWT) and paw withdrawal latency (PWL) were tested with Von Frey filaments and the radiant heat source of the test instrument, respectively...
March 14, 2018: Life Sciences
https://www.readbyqxmd.com/read/29506572/efficacy-and-safety-of-electrical-moxibustion-for-knee-osteoarthritis-study-protocol-for-a-randomized-controlled-trial
#20
Ha-Ra Kang, Chan-Yung Jung, Seung-Deok Lee, Kyung-Ho Kim, Kap-Sung Kim, Eun-Jung Kim
BACKGROUND: Knee osteoarthritis (KOA) is a significant health issue because it causes pain and functional limitation. Many studies have reported that moxibustion, a treatment in traditional Korean medicine, is effective in treating KOA. However, conventional moxibustion produces smoke, harmful gases, and odors that can adversely affect the eyes, skin, and throat. It is also difficult to control the intensity of stimulation in conventional moxibustion. An electrical moxibustion device was developed to circumvent these problems, but there are few studies of that device...
March 5, 2018: Trials
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