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https://www.readbyqxmd.com/read/28069562/effect-of-electroacupuncture-on-the-expression-of-agrin-and-acetylcholine-receptor-subtypes-in-rats-with-tibialis-anterior-muscular-atrophy-induced-by-sciatic-nerve-injection-injury
#1
Jianqi Yu, Meng Wang, Junying Liu, Xiaoming Zhang, Shengbo Yang
OBJECTIVE: To investigate the effects of electroacupuncture (EA) on mRNA and protein expression of agrin, acetylcholine receptor (AChR)-ε and AChR-γ in a rat model of tibialis anterior muscle atrophy induced by sciatic nerve injection injury, and to examine the underlying mechanism of action. METHODS: Fifty-four adult Sprague-Dawley rats were divided into four groups: healthy control group (CON, n=6); sciatic nerve injury group (SNI, n=24), comprising rats euthanased at 1, 2, 4 and 6 weeks, respectively, after penicillin injection-induced SNI (n=6 each); CON+EA group (n=12), comprising healthy rats euthanased at 4 and 6 weeks (after 2 and 4 weeks, respectively, of EA at GB30 and ST36); and SNI+EA group, comprising rats euthanased at 4 and 6 weeks (after 2 and 4 weeks, respectively, of EA)...
January 9, 2017: Acupuncture in Medicine: Journal of the British Medical Acupuncture Society
https://www.readbyqxmd.com/read/28069044/effect-of-transcutaneous-electrical-acupoint-stimulation-combined-with-palonosetron-on-chemotherapy-induced-nausea-and-vomiting-a-single-blind-randomized-controlled-trial
#2
Jing Xie, Lei-Hua Chen, Zhou-Yu Ning, Chen-Yue Zhang, Hao Chen, Zhen Chen, Zhi-Qiang Meng, Xiao-Yan Zhu
BACKGROUND: Chemotherapy-induced nausea and vomiting adversely affects the quality of life of patients who receive chemotherapy via intravenous infusion or transcatheter arterial chemoembolization (TACE). This study aimed to investigate the clinical effects of transcutaneous electrical acupoint stimulation (TEAS) on nausea and vomiting after TACE. METHODS: A total of 142 patients who received TACE with cisplatin for primary or metastatic liver cancer were assigned to the active-acupuncture (n = 72) or placebo-acupuncture (n = 70) groups using a covariate-adaptive randomization at a ratio of 1:1...
January 10, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28068994/spatiotemporal-changes-of-optical-signals-in-the-somatosensory-cortex-of-neuropathic-rats-after-electroacupuncture-stimulation
#3
Myeounghoon Cha, Younbyoung Chae, Sun Joon Bai, Bae Hwan Lee
BACKGROUND: Peripheral nerve injury causes physiological changes in primary afferent neurons. Neuropathic pain associated with peripheral nerve injuries may reflect changes in the excitability of the nervous system, including the spinothalamic tract. Current alternative medical research indicates that acupuncture stimulation has analgesic effects in various pain symptoms. However, activation changes in the somatosensory cortex of the brain by acupuncture stimulation remain poorly understood...
January 10, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28051128/electroacupuncture-treatment-partly-promotes-the-recovery-time-of-postoperative-ileus-by-activating-the-vagus-nerve-but-not-regulating-local-inflammation
#4
Jun-Fan Fang, Jian-Qiao Fang, Xiao-Mei Shao, Jun-Ying Du, Yi Liang, Wen Wang, Zhe Liu
Postoperative ileus (POI) after abdominal surgery significantly lowers the life quality of patients and increase hospital costs. However, few treatment strategies have successfully shortened the duration of POI. Electroacupuncture (EA) is a modern way of administering acupuncture and widely used in various gastrointestinal (GI) diseases in the world. Here, we studied the effect of EA on POI and its underlying mechanisms. Intestinal manipulation resulted in significant delays of GI transit, colonic transit and gastric emptying...
January 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28049463/coarse-needle-surface-potentiates-analgesic-effect-elicited-by-acupuncture-with-twirling-manipulation-in-rats-with-nociceptive-pain
#5
Sunoh Kwon, Yangseok Lee, Hi-Joon Park, Dae-Hyun Hahm
BACKGROUND: Biomechanical phenomenon called "needle grasp" through the winding of connective tissue has been proposed as an action mechanism of acupuncture manipulation. The aim of the present study is to verify whether the needle grasp force affects the pain-relieving activity of acupuncture in the tail-flick latency (TFL) and the rat paw formalin tests. METHODS: In order to make different roughness on the acupuncture needle surface, the needles with 0.2 mm-diameter were scratched using silicon carbide sandpapers with the grit numbers of 600 (mild coarse) and 200 (extra coarse)...
January 3, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28028627/effect-of-electroacupuncture-on-the-cervicospinal-p2x7-receptor-fractalkine-cx3cr1-signaling-pathway-in-a-rat-neck-incision-pain-model
#6
Y H Gao, C W Li, J Y Wang, L H Tan, C L Duanmu, X H Jing, X R Chang, J L Liu
Increasing evidence supports that acupuncture intervention is an effective approach for intraoperative and postoperative pain. Neuron-microglia crosstalk, mediated by the purinergic P2X7 receptor (R)/fractalkine/CX3CR1 cascade in the spinal cord dorsal horn, plays a pivotal role in pain processing. However, its involvement in the analgesic effect of electroacupuncture (EA) remains unclear. In this study, a rat neck-incision pain model was established by making a longitudinal incision along the midline of the neck and subsequent repeated mechanical stimulation...
December 27, 2016: Purinergic Signalling
https://www.readbyqxmd.com/read/27999821/effects-of-electroacupuncture-on-the-daily-rhythmicity-of-intestinal-movement-and-circadian-rhythmicity-of-colonic-per2-expression-in-rats-with-spinal-cord-injury
#7
Jie Cheng, Xueqiang Wang, Jiabao Guo, Yujie Yang, Wenyi Zhang, Bin Xie, Zhaojin Zhu, Yuemei Lu, Yi Zhu
Background. Spinal cord injury (SCI) leads to bowel dysfunction. Electroacupuncture (EA) may improve bowel function. Objective. To assess EA on daily rhythmicity of intestinal movement and circadian rhythmicity of colonic Per2 expression in rats with SCI. Methods. Rats were randomized to the sham, SCI, and SCI+EA groups. EA was performed at bilateral Zusanli point (ST36) during daytime (11:00-11:30) for 14 days following SCI. Intestinal transit and daily rhythmicity of intestinal movement were assessed. Circadian rhythmicity of colonic Per2 expression was assessed by real-time RT-PCR...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27979946/draft-genome-sequences-of-four-propionibacterium-acnes-strains-isolated-from-implant-related-infections
#8
Guillaume Ghislain Aubin, Stanimir Kambarev, Aurélie Guillouzouic, Didier Lepelletier, Pascale Bémer, Stéphane Corvec
Propionibacterium acnes was previously described as a potential implant-related pathogen. Here, we report the draft genome sequence of four P. acnes strains, isolated from spine material, hip arthroplasty, and knee arthroplasty infections in France belonging to different sequence types (ST18, ST27, and ST36).
December 15, 2016: Genome Announcements
https://www.readbyqxmd.com/read/27978835/activation-of-hippocampal-mek1-contributes-to-the-cumulative-antinociceptive-effect-of-electroacupuncture-in-neuropathic-pain-rats
#9
Yong-Hui Gao, Cheng-Wen Li, Jun-Ying Wang, Yu Kan, Lian-Hong Tan, Xiang-Hong Jing, Jun-Ling Liu
BACKGROUND: Electroacupuncture (EA) intervention can relieve a variety of pain; however, optimal EA protocols have not been clearly determined. In addition, although central mitogen-activated protein kinase kinase (MEK) signaling has been shown to be involved in the antinociceptive effect of acupuncture stimulation, its characteristics at different time-points of EA intervention have not been fully elucidated. Therefore, the present study investigated the relationship between the effects of different numbers of EA intervention sessions and the activation of MEK1 in the hippocampus and hypothalamus in a rat model of neuropathic pain...
December 15, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27966183/electro-acupuncture-at-acupoint-st36-ameliorates-inflammation-and-regulates-th1-th2-balance-in-delayed-type-hypersensitivity
#10
Zhigang Wang, Tao Chen, Man Long, Longyun Chen, Lei Wang, Nina Yin, Zebin Chen
Increasing evidence indicates anti-allergic and anti-inflammatory effects of electro-acupuncture (EA) therapy. However, its underlying mechanism on delayed-type hypersensitivity (DTH), a classic allergic inflammatory disease, still remains unclear. In this study, we aimed to explore the immunomodulatory mechanism of EA intervention in a mouse model of ovalbumin (OVA)-induced DTH. Mice were randomly divided into four groups: Control, OVA-DTH, DTH + EA, DTH + Sham. "Zusanli" acupoint (ST36) was used for DTH + EA, whereas a non-acupoint (localized 5 mm below the "Zusanli" acupoint) was selected for DTH + Sham...
December 13, 2016: Inflammation
https://www.readbyqxmd.com/read/27919312/lessons-from-an-outbreak-of-legionnaires-disease-on-a-hematology-oncology-unit
#11
Louise K Francois Watkins, Karrie-Ann E Toews, Aaron M Harris, Sherri Davidson, Stephanie Ayers-Millsap, Claressa E Lucas, Brian C Hubbard, Natalia A Kozak-Muiznieks, Edward Khan, Preeta K Kutty
OBJECTIVES To define the scope of an outbreak of Legionnaires' disease (LD), to identify the source, and to stop transmission. DESIGN AND SETTING Epidemiologic investigation of an LD outbreak among patients and a visitor exposed to a newly constructed hematology-oncology unit. METHODS An LD case was defined as radiographically confirmed pneumonia in a person with positive urinary antigen testing and/or respiratory culture for Legionella and exposure to the hematology-oncology unit after February 20, 2014. Cases were classified as definitely or probably healthcare-associated based on whether they were exposed to the unit for all or part of the incubation period (2-10 days)...
December 6, 2016: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/27902400/comparative-analysis-of-phenol-soluble-modulin-production-and-galleria-mellonella-killing-by-community-associated-and-healthcare-associated-meticillin-resistant-staphylococcusaureus-strains
#12
Eve Boakes, Helene Marbach, Steven Lynham, Malcolm Ward, Jonathan D Edgeworth, Jonathan A Otter
Community-associated meticillin-resistant Staphylococcus aureus (CA-MRSA) have emerged globally and have been associated with more severe disease than healthcare-associated MRSA (HA-MRSA). The purpose of this study was to determine whether laboratory measures of virulence can distinguish dominant CA-MRSA clones from HA-MRSA clones. We compared the production of phenol-soluble modulins (PSMs) and ability to kill Galleria mellonella caterpillars for a range of CA- and HA-MRSA strains. Twenty-two HA-MRSA strains [ST22-IV (EMRSA-15), ST36-II (EMRSA-16) and ST239-III] and 26 CA-MRSA strains [ST1-IV (PVL+ USA400), ST1-IV (PVL-), ST8-IV (USA300), ST22-IV (PVL+), ST30-IV, ST59-IV and ST80-IV] were analysed...
December 2016: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/27896621/distinct-roles-of-asic3-and-trpv1-receptors-in-electroacupuncture-induced-segmental-and-systemic-analgesia
#13
Juanjuan Xin, Yangshuai Su, Zhaokun Yang, Wei He, Hong Shi, Xiaoyu Wang, Ling Hu, Xiaochun Yu, Xianghong Jing, Bing Zhu
Previous studies have demonstrated the effects of different afferent fibers on electroacupuncture (EA)-induced analgesia. However, contributions of functional receptors expressed on afferent fibers to the EA analgesia remain unclear. This study investigates the roles of acid-sensing ion channel 3 (ASIC3) and transient receptor potential vanilloid 1 (TRPV1) receptors in EA-induced segmental and systemic analgesia. Effects of EA at acupoint ST36 with different intensities on the C-fiber reflex and mechanical and thermal pain thresholds were measured among the ASIC3(-/-), TRPV1(-/-), and C57BL/6 mice...
November 28, 2016: Frontiers of Medicine
https://www.readbyqxmd.com/read/27832623/comparing-the-effectiveness-of-electroacupuncture-with-different-grades-of-knee-osteoarthritis-a-prospective-study
#14
Li Qi, Yonggang Tang, Yong You, Fengling Qin, Lijuan Zhai, Hongxia Peng, Rongrong Nie
BACKGROUND: The electroacupuncture (EA) with different number of points significantly affected its efficacy on knee osteoarthritis (KOA), and the severity of KOA also influenced its response to treatments. Hence, we prospectively compared the clinical efficacy of EA on KOA with different severities. METHODS: A total of 132 KOA patients recruited from 181st Central Hospital of The Chinese People's Liberation Army between March 2014 and March 2015 were classified into 4 KOA stages according to Kellgren Lawrence grading scale...
2016: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/27821107/acupuncture-with-different-acupoint-combinations-for-chemotherapy-induced-nausea-and-vomiting-study-protocol-for-a-randomized-controlled-trial
#15
RANDOMIZED CONTROLLED TRIAL
Lili Gao, Bo Chen, Qiwen Zhang, Tianyi Zhao, Bo Li, Tao Sha, Jinxin Zou, Yongming Guo, Xingfang Pan, Yi Guo
BACKGROUND: Acupuncture is beneficial for controlling chemotherapy-induced nausea and vomiting (CINV). However, the effect of different acupoint combinations on controlling CINV remains unknown. This study aims to compare the effects of distal-proximal point association and local distribution point association on controlling CINV. METHODS/DESIGN: The study is a single-center, randomized controlled trial. A total of 240 participants will be randomly divided into four groups...
November 8, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27807402/more-than-deqi-spatial-patterns-of-acupuncture-induced-bodily-sensations
#16
Won-Mo Jung, Woosun Shim, Taehyung Lee, Hi-Joon Park, Yeonhee Ryu, Florian Beissner, Younbyoung Chae
Acupuncture uses needles to stimulate certain parts of the body, inducing a specific sensation, termed DeQi, which regard as essential for acupuncture's therapeutic effect. Here, we used the newly developed tool, bodily sensation mapping, to investigate the spatial configuration of acupuncture-induced sensations throughout the body. Twenty-five participants randomly received acupuncture stimulation or tactile stimulation using a von Frey filament at four different acupoints (HT7, PC6, ST36, and SP10) on the left side of the body...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27803655/sustained-effects-of-acupuncture-stimulation-investigated-with-centrality-mapping-analysis
#17
Xiangyu Long, Wenjing Huang, Vitaly Napadow, Fanrong Liang, Burkhard Pleger, Arno Villringer, Claudia M Witt, Till Nierhaus, Daniel Pach
: Acupuncture can have instant and sustained effects, however, its mechanisms of action are still unclear. Here, we investigated the sustained effect of acupuncture by evaluating centrality changes in resting-state functional magnetic resonance imaging after manually stimulating the acupuncture point ST36 at the lower leg or two control point locations (CP1 same dermatome, CP2 different dermatome). Data from a previously published experiment evaluating instant BOLD effects and S2-seed-based resting state connectivity was re-analyzed using eigenvector centrality mapping and degree centrality mapping...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27800006/the-effect-of-repeated-electroacupuncture-analgesia-on-neurotrophic-and-cytokine-factors-in-neuropathic-pain-rats
#18
Junying Wang, Yonghui Gao, Shuping Chen, Chenlin Duanmu, Jianliang Zhang, Xiumei Feng, Yaxia Yan, Junling Liu, Gerhard Litscher
Chronic pain is a common disability influencing quality of life. Results of previous studies showed that acupuncture has a cumulative analgesic effect, but the relationship with spinal cytokines neurotrophic factors released by astrocytes remains unknown. The present study was designed to observe the effect of electroacupuncture (EA) treatment on spinal cytokines neurotrophic factors in chronic neuropathic pain rats. The chronic neuropathic pain was established by chronic constrictive injury (CCI). EA treatment was applied at Zusanli (ST36) and Yanglingquan (GB34) (both bilateral) once a day, for 30 min...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27776494/moxibustion-treatment-for-diarrhea-predominant-irritable-bowel-syndrome-study-protocol-for-a-randomized-controlled-trial
#19
Chunhui Bao, Jingzhi Zhang, Jinmei Liu, Huirong Liu, Luyi Wu, Yin Shi, Jing Li, Zhihai Hu, Yongzheng Dong, Siyao Wang, Xiaoqing Zeng, Huangan Wu
BACKGROUND: Irritable bowel syndrome (IBS) is a worldwide disease with high morbidity. The effect of current treatment with Western medicine is not satisfactory. Although moxibustion treatment is widely used for gastrointestinal diseases, randomized controlled trials on the use of this treatment for IBS are limited. This study aims to evaluate the clinical efficacy and safety of moxibustion treatment in patients with diarrhea-predominant irritable bowel syndrome (IBS-D). METHODS/DESIGN: A multi-center, randomized, single-blind and placebo-controlled trial is employed...
October 24, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27775047/repetitive-electroacupuncture-attenuates-cold-induced-hypertension-through-enkephalin-in-the-rostral-ventral-lateral-medulla
#20
Min Li, Stephanie C Tjen-A-Looi, Zhi-Ling Guo, John C Longhurst
Acupuncture lowers blood pressure (BP) in hypertension, but mechanisms underlying its action are unclear. To simulate clinical studies, we performed electroacupuncture (EA) in unanesthetized rats with cold-induced hypertension (CIH) induced by six weeks of cold exposure (6 °C). EA (0.1 - 0.4 mA, 2 Hz) was applied at ST36-37 acupoints overlying the deep peroneal nerve for 30 min twice weekly for five weeks while sham-EA was conducted with the same procedures as EA except for no electrical stimulation...
October 24, 2016: Scientific Reports
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